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Conserved domains on  [gi|158431146]
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Chain B, Slit Homolog 2 Protein N-product

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
15-164 4.42e-14

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.35  E-value: 4.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  15 IVDCRGKGLTEIPTNLPE--TITEIRLEQNTIKVIPPgAFSPYKKLRRIDLSNNQISELaPDAFQGLRSLNSLVLYGNKI 92
Cdd:COG4886  140 ELDLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQL 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  93 TELPKSLfeglfslqlllLNANKIN*LRVD--------AFQDLHNLNLLSLYDNKLQTIakGTFSPLRAIQTMHLAQNPF 164
Cdd:COG4886  218 TDLPEPL-----------ANLTNLETLDLSnnqltdlpELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQL 284
PCC super family cl28216
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 135-198 8.55e-06

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


The actual alignment was detected with superfamily member TIGR00864:

Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 46.23  E-value: 8.55e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 158431146   135 LYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIET---SGARCTSPRRLANK 198
Cdd:TIGR00864    2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpEAALCAGPGALAGQ 68
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
15-164 4.42e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.35  E-value: 4.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  15 IVDCRGKGLTEIPTNLPE--TITEIRLEQNTIKVIPPgAFSPYKKLRRIDLSNNQISELaPDAFQGLRSLNSLVLYGNKI 92
Cdd:COG4886  140 ELDLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQL 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  93 TELPKSLfeglfslqlllLNANKIN*LRVD--------AFQDLHNLNLLSLYDNKLQTIakGTFSPLRAIQTMHLAQNPF 164
Cdd:COG4886  218 TDLPEPL-----------ANLTNLETLDLSnnqltdlpELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQL 284
LRR_8 pfam13855
Leucine rich repeat;
35-92 9.45e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 58.30  E-value: 9.45e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 158431146   35 TEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI 92
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
19-99 7.51e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.01  E-value: 7.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  19 RGKGLTEIPTNLPETITEIRLEQNTIKVIP---PGAfspykkLRRIDLSNNQISELAPDAFQGLRSLNslvLYGNKITEL 95
Cdd:PRK15370 228 NSNQLTSIPATLPDTIQEMELSINRITELPerlPSA------LQSLDLFHNKISCLPENLPEELRYLS---VYDNSIRTL 298


                 ....
gi 158431146  96 PKSL 99
Cdd:PRK15370 299 PAHL 302
LRRNT smart00013
Leucine rich repeat N-terminal domain;
4-36 2.93e-07

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 45.39  E-value: 2.93e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 158431146     4 HCPAACTCSNNIVDCRGKGLTEIPTNLPETITE 36
Cdd:smart00013   1 ACPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 135-198 8.55e-06

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 46.23  E-value: 8.55e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 158431146   135 LYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIET---SGARCTSPRRLANK 198
Cdd:TIGR00864    2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpEAALCAGPGALAGQ 68
LRRCT smart00082
Leucine rich repeat C-terminal domain;
162-192 2.28e-05

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 40.49  E-value: 2.28e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 158431146   162 NPFICDCHLKWLADYLHTNPI--ETSGARCTSP 192
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHlqDPVDLRCASP 33
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
15-164 4.42e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.35  E-value: 4.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  15 IVDCRGKGLTEIPTNLPE--TITEIRLEQNTIKVIPPgAFSPYKKLRRIDLSNNQISELaPDAFQGLRSLNSLVLYGNKI 92
Cdd:COG4886  140 ELDLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQL 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  93 TELPKSLfeglfslqlllLNANKIN*LRVD--------AFQDLHNLNLLSLYDNKLQTIakGTFSPLRAIQTMHLAQNPF 164
Cdd:COG4886  218 TDLPEPL-----------ANLTNLETLDLSnnqltdlpELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQL 284
LRR_8 pfam13855
Leucine rich repeat;
35-92 9.45e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 58.30  E-value: 9.45e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 158431146   35 TEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI 92
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
51-162 7.94e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 57.64  E-value: 7.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  51 AFSPYKKLRRIDLSNNQISELaPDAFQGLRSLNSLVLYGNKITELPKSLFEgLFSLQLLLLNANKIN*LRvDAFQDLHNL 130
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGN-LTNLKSLDLSNNQLTDLP-EELGNLTNL 184

                         90       100       110
                 ....*....|....*....|....*....|..
gi 158431146 131 NLLSLYDNKLQTIAKgTFSPLRAIQTMHLAQN 162
Cdd:COG4886  185 KELDLSNNQITDLPE-PLGNLTNLEELDLSGN 215
LRR_8 pfam13855
Leucine rich repeat;
112-164 2.21e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 2.21e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 158431146  112 NANKIN*LRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPF 164
Cdd:pfam13855   9 SNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
57-140 3.06e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 3.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146   57 KLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKslfeglfslqllllnankin*lrvDAFQDLHNLNLLSLY 136
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSP------------------------GAFSGLPSLRYLDLS 57


                  ....
gi 158431146  137 DNKL 140
Cdd:pfam13855  58 GNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
19-99 7.51e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.01  E-value: 7.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  19 RGKGLTEIPTNLPETITEIRLEQNTIKVIP---PGAfspykkLRRIDLSNNQISELAPDAFQGLRSLNslvLYGNKITEL 95
Cdd:PRK15370 228 NSNQLTSIPATLPDTIQEMELSINRITELPerlPSA------LQSLDLFHNKISCLPENLPEELRYLS---VYDNSIRTL 298


                 ....
gi 158431146  96 PKSL 99
Cdd:PRK15370 299 PAHL 302
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
22-143 1.67e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 51.24  E-value: 1.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  22 GLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKL------------------RRIDLSNNQISELA---PDAFQglr 80
Cdd:PRK15370 189 GLTTIPACIPEQITTLILDNNELKSLPENLQGNIKTLyansnqltsipatlpdtiQEMELSINRITELPerlPSALQ--- 265

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158431146  81 slnSLVLYGNKITELPKSLFEGlfslqllllnankin*lrvdafqdlhnLNLLSLYDNKLQTI 143
Cdd:PRK15370 266 ---SLDLFHNKISCLPENLPEE---------------------------LRYLSVYDNSIRTL 298
LRRNT smart00013
Leucine rich repeat N-terminal domain;
4-36 2.93e-07

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 45.39  E-value: 2.93e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 158431146     4 HCPAACTCSNNIVDCRGKGLTEIPTNLPETITE 36
Cdd:smart00013   1 ACPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 5-31 3.07e-06

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 42.61  E-value: 3.07e-06
                          10        20
                  ....*....|....*....|....*..
gi 158431146    5 CPAACTCSNNIVDCRGKGLTEIPTNLP 31
Cdd:pfam01462   2 CPVPCHCSATVVNCSDRGLTAVPRDLP 28
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 135-198 8.55e-06

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 46.23  E-value: 8.55e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 158431146   135 LYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIET---SGARCTSPRRLANK 198
Cdd:TIGR00864    2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpEAALCAGPGALAGQ 68
LRRCT smart00082
Leucine rich repeat C-terminal domain;
162-192 2.28e-05

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 40.49  E-value: 2.28e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 158431146   162 NPFICDCHLKWLADYLHTNPI--ETSGARCTSP 192
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHlqDPVDLRCASP 33
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
11-96 6.60e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 40.15  E-value: 6.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  11 CSNN---IVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPpgAFSPykKLRRIDLSNNQISELaPDAFQGLRSLNslvL 87
Cdd:PRK15387 198 CLNNgnaVLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLP--ALPP--ELRTLEVSGNQLTSL-PVLPPGLLELS---I 269


                 ....*....
gi 158431146  88 YGNKITELP 96
Cdd:PRK15387 270 FSNPLTHLP 278
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 29-99 8.23e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.83  E-value: 8.23e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 158431146  29 NLPEtITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT-ELPKSL 99
Cdd:PLN00113 497 SLSE-LMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNL 567
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 56-181 1.96e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 38.62  E-value: 1.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  56 KKLRRIDLSNNQIS-----ELApDAFQGLRSLNSLVLYGNKITE-----LPKSLfEGLFSLQLLLLNANKIN*LRVDAFQ 125
Cdd:COG5238  236 KSLTTLDLSNNQIGdegviALA-EALKNNTTVETLYLSGNQIGAegaiaLAKAL-QGNTTLTSLDLSVNRIGDEGAIALA 313

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158431146 126 DL----HNLNLLSLYDNKLQTI-AKGTFSPL---RAIQTMHLAQNPfICDCHLKWLADYLHTNP 181
Cdd:COG5238  314 EGlqgnKTLHTLNLAYNGIGAQgAIALAKALqenTTLHSLDLSDNQ-IGDEGAIALAKYLEGNT 376
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
 21-102 2.26e-03

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 36.75  E-value: 2.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146   21 KGLTEIptNLPETITEIR--------LE----QNTIKVIPPGAFSPYKKLRRIDLSNNqISELAPDAFQGLrSLNSLVLy 88
Cdd:pfam13306  34 TSLKSI--TLPSSLTSIGsyafyncsLTsitiPSSLTSIGEYAFSNCSNLKSITLPSN-LTSIGSYAFSNC-SLKSITI- 108

                          90
                  ....*....|....
gi 158431146   89 GNKITELPKSLFEG 102
Cdd:pfam13306 109 PSSVTTIGSYAFSN 122
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 56-140 2.90e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 38.29  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  56 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT-ELPKSLfEGLFSLQLLLLNANKIN*LRVDAFQDLHNLNLLS 134
Cdd:PLN00113 475 KRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDEL-SSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLD 553


                 ....*.
gi 158431146 135 LYDNKL 140
Cdd:PLN00113 554 LSQNQL 559
LRR smart00370
Leucine-rich repeats, outliers;
57-78 3.66e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 33.86  E-value: 3.66e-03
                           10        20
                   ....*....|....*....|..
gi 158431146    57 KLRRIDLSNNQISELAPDAFQG 78
Cdd:smart00370   3 NLRELDLSNNQLSSLPPGAFQG 24
LRR_TYP smart00369
Leucine-rich repeats, typical (most populated) subfamily;
57-78 3.66e-03

Leucine-rich repeats, typical (most populated) subfamily;


Pssm-ID: 197687 [Multi-domain]  Cd Length: 24  Bit Score: 33.86  E-value: 3.66e-03
                           10        20
                   ....*....|....*....|..
gi 158431146    57 KLRRIDLSNNQISELAPDAFQG 78
Cdd:smart00369   3 NLRELDLSNNQLSSLPPGAFQG 24
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
6-165 6.85e-03

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 36.98  E-value: 6.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146   6 PAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAfsPyKKLRRIDLSNNQISELAPDAFQGLRSLNsl 85
Cdd:PRK15370 236 PATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENL--P-EELRYLSVYDNSIRTLPAHLPSGITHLN-- 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158431146  86 vLYGNKITELPKSLFEGlfsLQLLLLNANKIN*LRVDAFQDLHNlnlLSLYDNKLqTIAKGTFSPlrAIQTMHLAQNPFI 165
Cdd:PRK15370 311 -VQSNSLTALPETLPPG---LKTLEAGENALTSLPASLPPELQV---LDVSKNQI-TVLPETLPP--TITTLDVSRNALT 380
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 56-96 7.73e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 33.37  E-value: 7.73e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 158431146   56 KKLRRIDLSNNQISELapDAFQGLRSLNSLVLYGN-KITELP 96
Cdd:pfam12799   1 PNLEVLDLSNNQITDI--PPLAKLPNLETLDLSGNnKITDLS 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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