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Conserved domains on  [gi|1582935350|gb|TBH14755|]
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hypothetical protein ETP66_11665 [Thermus thermamylovorans]

Protein Classification

COG4634 family protein( domain architecture ID 10008645)

COG4634 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4634 COG4634
Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component [General ...
 1-113 1.80e-16

Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component [General function prediction only];


:

Pssm-ID: 443672  Cd Length: 113  Bit Score: 69.13  E-value: 1.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1582935350   1 MKLLLDENVERALFLGLKRRhpGLDVVRVVDVGLGGRSDAEVLEWAAREGRVLVS--RDHATLSaeaARRieeGRPMSGL 78
Cdd:COG4634     1 MKFLLDENLSPRLVEWLREA--GHDVLHVRDLGLPGASDEEILEYARREGRIIVTkdKDFGELL---ALS---GAPPPGI 72

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1582935350  79 ILLRRG-VGVGRILEDLELLLTAARPGELENAILYL 113
Cdd:COG4634    73 ILLRLGnLSPEELAELLRRVLERIEEFLLEGALIVV 108
 
Name Accession Description Interval E-value
COG4634 COG4634
Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component [General ...
 1-113 1.80e-16

Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component [General function prediction only];


Pssm-ID: 443672  Cd Length: 113  Bit Score: 69.13  E-value: 1.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1582935350   1 MKLLLDENVERALFLGLKRRhpGLDVVRVVDVGLGGRSDAEVLEWAAREGRVLVS--RDHATLSaeaARRieeGRPMSGL 78
Cdd:COG4634     1 MKFLLDENLSPRLVEWLREA--GHDVLHVRDLGLPGASDEEILEYARREGRIIVTkdKDFGELL---ALS---GAPPPGI 72

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1582935350  79 ILLRRG-VGVGRILEDLELLLTAARPGELENAILYL 113
Cdd:COG4634    73 ILLRLGnLSPEELAELLRRVLERIEEFLLEGALIVV 108
DUF5615 pfam18480
Domain of unknown function (DUF5615); This is a domain of unknown function found in potential ...
 1-84 7.94e-15

Domain of unknown function (DUF5615); This is a domain of unknown function found in potential toxin-antitoxin system component.


Pssm-ID: 465782  Cd Length: 77  Bit Score: 63.69  E-value: 7.94e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1582935350   1 MKLLLDENVERALflGLKRRHPGLDVVRVVDVGLGGRSDAEVLEWAAREGRVLVSRDhatlsAEAARRIEEGRPMSGLIL 80
Cdd:pfam18480   1 MKLLADENLSPRL--VELLRDLGHDVLHVRELGLPGASDEEILEYAKEEGRIIVTKD-----KDFGELHLLGGPPPGVIL 73


                  ....
gi 1582935350  81 LRRG 84
Cdd:pfam18480  74 LRLG 77
 
Name Accession Description Interval E-value
COG4634 COG4634
Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component [General ...
 1-113 1.80e-16

Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component [General function prediction only];


Pssm-ID: 443672  Cd Length: 113  Bit Score: 69.13  E-value: 1.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1582935350   1 MKLLLDENVERALFLGLKRRhpGLDVVRVVDVGLGGRSDAEVLEWAAREGRVLVS--RDHATLSaeaARRieeGRPMSGL 78
Cdd:COG4634     1 MKFLLDENLSPRLVEWLREA--GHDVLHVRDLGLPGASDEEILEYARREGRIIVTkdKDFGELL---ALS---GAPPPGI 72

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1582935350  79 ILLRRG-VGVGRILEDLELLLTAARPGELENAILYL 113
Cdd:COG4634    73 ILLRLGnLSPEELAELLRRVLERIEEFLLEGALIVV 108
DUF5615 pfam18480
Domain of unknown function (DUF5615); This is a domain of unknown function found in potential ...
 1-84 7.94e-15

Domain of unknown function (DUF5615); This is a domain of unknown function found in potential toxin-antitoxin system component.


Pssm-ID: 465782  Cd Length: 77  Bit Score: 63.69  E-value: 7.94e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1582935350   1 MKLLLDENVERALflGLKRRHPGLDVVRVVDVGLGGRSDAEVLEWAAREGRVLVSRDhatlsAEAARRIEEGRPMSGLIL 80
Cdd:pfam18480   1 MKLLADENLSPRL--VELLRDLGHDVLHVRELGLPGASDEEILEYAKEEGRIIVTKD-----KDFGELHLLGGPPPGVIL 73


                  ....
gi 1582935350  81 LRRG 84
Cdd:pfam18480  74 LRLG 77
PIN_10 pfam18478
PIN like domain; This is a bacterial domain of unknown function suggested to resemble PIN like ...
 1-68 1.68e-03

PIN like domain; This is a bacterial domain of unknown function suggested to resemble PIN like domains.


Pssm-ID: 436531  Cd Length: 83  Bit Score: 34.95  E-value: 1.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1582935350   1 MKLLLDENVERALFLGLKRRHP-GLDVVRVVDVGLGGRSDAEVLEWAAREGRVLVSRDHATLSAEAARR 68
Cdd:pfam18478   1 MKFFLDENLPPALAKALRALFAeGHEVVHLRDHFAAGTPDEEWIPALAEGGWVVLTKDRRIRKRPAERA 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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