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Conserved domains on  [gi|157886259|gb|ABV91641|]
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RNA-dependent RNA polymerase, partial [Hantaanvirus CGAa2]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bunya_RdRp super family cl20265
Bunyavirus RNA dependent RNA polymerase; The bunyaviruses are enveloped viruses with a genome ...
 3-131 6.20e-46

Bunyavirus RNA dependent RNA polymerase; The bunyaviruses are enveloped viruses with a genome consisting of 3 ssRNA segments (called L, M and S). The nucleocapsid protein is encode on the small (S) genomic RNA. The L segment codes for an RNA polymerase. This family contains the RNA dependent RNA polymerase on the L segment.


The actual alignment was detected with superfamily member pfam04196:

Pssm-ID: 282102  Cd Length: 739  Bit Score: 158.02  E-value: 6.20e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157886259    3 FRTVTSMLHNGLPNNKLKNCVIDALKQV-YKTDFFMSRKLRNYIDNMESLDPHIKQFLDFFPDGHHGEVKGNWLQGNLNK 81
Cdd:pfam04196 451 YKYFFLIALLPILYPKEKFLGLYLLCNYmSKTDLLPSDILLNLVDQKYYGRYDIIFWMTNGLNKNFVEVKRNWLQGNLNY 530

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 157886259   82 CSSLFGVAMSLLFKQVWNNLFPELD--CFFEFAHHSDDALFIYGYLEPVDDG 131
Cdd:pfam04196 531 TSSLVHSCAMEVYKEFLKRAIKLLDgsCLVNSIVHSDDSQTSISIPCHVDDK 582
 
Name Accession Description Interval E-value
Bunya_RdRp pfam04196
Bunyavirus RNA dependent RNA polymerase; The bunyaviruses are enveloped viruses with a genome ...
 3-131 6.20e-46

Bunyavirus RNA dependent RNA polymerase; The bunyaviruses are enveloped viruses with a genome consisting of 3 ssRNA segments (called L, M and S). The nucleocapsid protein is encode on the small (S) genomic RNA. The L segment codes for an RNA polymerase. This family contains the RNA dependent RNA polymerase on the L segment.


Pssm-ID: 282102  Cd Length: 739  Bit Score: 158.02  E-value: 6.20e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157886259    3 FRTVTSMLHNGLPNNKLKNCVIDALKQV-YKTDFFMSRKLRNYIDNMESLDPHIKQFLDFFPDGHHGEVKGNWLQGNLNK 81
Cdd:pfam04196 451 YKYFFLIALLPILYPKEKFLGLYLLCNYmSKTDLLPSDILLNLVDQKYYGRYDIIFWMTNGLNKNFVEVKRNWLQGNLNY 530

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 157886259   82 CSSLFGVAMSLLFKQVWNNLFPELD--CFFEFAHHSDDALFIYGYLEPVDDG 131
Cdd:pfam04196 531 TSSLVHSCAMEVYKEFLKRAIKLLDgsCLVNSIVHSDDSQTSISIPCHVDDK 582
 
Name Accession Description Interval E-value
Bunya_RdRp pfam04196
Bunyavirus RNA dependent RNA polymerase; The bunyaviruses are enveloped viruses with a genome ...
 3-131 6.20e-46

Bunyavirus RNA dependent RNA polymerase; The bunyaviruses are enveloped viruses with a genome consisting of 3 ssRNA segments (called L, M and S). The nucleocapsid protein is encode on the small (S) genomic RNA. The L segment codes for an RNA polymerase. This family contains the RNA dependent RNA polymerase on the L segment.


Pssm-ID: 282102  Cd Length: 739  Bit Score: 158.02  E-value: 6.20e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157886259    3 FRTVTSMLHNGLPNNKLKNCVIDALKQV-YKTDFFMSRKLRNYIDNMESLDPHIKQFLDFFPDGHHGEVKGNWLQGNLNK 81
Cdd:pfam04196 451 YKYFFLIALLPILYPKEKFLGLYLLCNYmSKTDLLPSDILLNLVDQKYYGRYDIIFWMTNGLNKNFVEVKRNWLQGNLNY 530

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 157886259   82 CSSLFGVAMSLLFKQVWNNLFPELD--CFFEFAHHSDDALFIYGYLEPVDDG 131
Cdd:pfam04196 531 TSSLVHSCAMEVYKEFLKRAIKLLDgsCLVNSIVHSDDSQTSISIPCHVDDK 582
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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