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Conserved domains on  [gi|157804750|gb|ABV80014|]
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AprB, partial [Thiocapsa pendens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
aprB super family cl31164
adenosine phosphosulphate reductase, beta subunit; During dissimilatory sulfate reduction and ...
 1-98 6.48e-45

adenosine phosphosulphate reductase, beta subunit; During dissimilatory sulfate reduction and sulfur oxidation, adenylylsulfate (APS) reductase catalyzes reversibly the two-electron reduction of APS to sulfite and AMP. Found in several bacterial lineages and in Archaeoglobales, APS reductase is a heterodimer composed of an alpha subunit containing a noncovalently bound FAD, and a beta subunit containing two [4Fe-4S] clusters. Described by this model is the beta subunit of APS reductase, sharing common evolutionary origin with other iron-sulfur cluster-binding proteins. [Central intermediary metabolism, Sulfur metabolism]


The actual alignment was detected with superfamily member TIGR02060:

Pssm-ID: 131115 [Multi-domain]  Cd Length: 132  Bit Score: 142.43  E-value: 6.48e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157804750    1 LMKLDNDgsetghAMKAFNQEPEQCWECYSCVKICPQQAIECRHYADVVPMGASVQPLRGTDSIMWTIKFRNGNMKRFKF 80
Cdd:TIGR02060  29 LMHLDTE------IMKAYNIEPDMCWECYSCVKACPQGAIDVRGYADFAPLGGSCRPMRDEEKIMWTVKFRNGKVMRFKF 102

                          90
                  ....*....|....*...
gi 157804750   81 PIRTTPEGSIDPYGSKPE 98
Cdd:TIGR02060 103 PIRTTPWGSITPFEGVPE 120
 
Name Accession Description Interval E-value
aprB TIGR02060
adenosine phosphosulphate reductase, beta subunit; During dissimilatory sulfate reduction and ...
 1-98 6.48e-45

adenosine phosphosulphate reductase, beta subunit; During dissimilatory sulfate reduction and sulfur oxidation, adenylylsulfate (APS) reductase catalyzes reversibly the two-electron reduction of APS to sulfite and AMP. Found in several bacterial lineages and in Archaeoglobales, APS reductase is a heterodimer composed of an alpha subunit containing a noncovalently bound FAD, and a beta subunit containing two [4Fe-4S] clusters. Described by this model is the beta subunit of APS reductase, sharing common evolutionary origin with other iron-sulfur cluster-binding proteins. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 131115 [Multi-domain]  Cd Length: 132  Bit Score: 142.43  E-value: 6.48e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157804750    1 LMKLDNDgsetghAMKAFNQEPEQCWECYSCVKICPQQAIECRHYADVVPMGASVQPLRGTDSIMWTIKFRNGNMKRFKF 80
Cdd:TIGR02060  29 LMHLDTE------IMKAYNIEPDMCWECYSCVKACPQGAIDVRGYADFAPLGGSCRPMRDEEKIMWTVKFRNGKVMRFKF 102

                          90
                  ....*....|....*...
gi 157804750   81 PIRTTPEGSIDPYGSKPE 98
Cdd:TIGR02060 103 PIRTTPWGSITPFEGVPE 120
APS-reductase_C pfam12139
Adenosine-5'-phosphosulfate reductase beta subunit; This family of proteins is found in ...
 43-98 3.48e-34

Adenosine-5'-phosphosulfate reductase beta subunit; This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 112 to 142 amino acids in length. This family is found in association with pfam00037, and has a conserved FPIRTT sequence motif. The whole beta subunit has the enzymic properties of EC:1.8.99.2.


Pssm-ID: 432356  Cd Length: 82  Bit Score: 113.65  E-value: 3.48e-34
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 157804750   43 RHYADVVPMGASVQPLRGTDSIMWTIKFRNGNMKRFKFPIRTTPEGSIDPYGSKPE 98
Cdd:pfam12139   2 RGYADFVPLGASVVPLRGSEDIMWTVKFRNGKVKRFKFPIRTTPEGSAIPLAGFPE 57
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 2-47 5.52e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 41.23  E-value: 5.52e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 157804750   2 MKLDNDGsetghaMKAFNQEPEQCWECYSCVKICPQQAIECRHYAD 47
Cdd:COG1146   25 LELDEEG------KKALVINPEECIGCGACELVCPVGAITVEDDEP 64
 
Name Accession Description Interval E-value
aprB TIGR02060
adenosine phosphosulphate reductase, beta subunit; During dissimilatory sulfate reduction and ...
 1-98 6.48e-45

adenosine phosphosulphate reductase, beta subunit; During dissimilatory sulfate reduction and sulfur oxidation, adenylylsulfate (APS) reductase catalyzes reversibly the two-electron reduction of APS to sulfite and AMP. Found in several bacterial lineages and in Archaeoglobales, APS reductase is a heterodimer composed of an alpha subunit containing a noncovalently bound FAD, and a beta subunit containing two [4Fe-4S] clusters. Described by this model is the beta subunit of APS reductase, sharing common evolutionary origin with other iron-sulfur cluster-binding proteins. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 131115 [Multi-domain]  Cd Length: 132  Bit Score: 142.43  E-value: 6.48e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157804750    1 LMKLDNDgsetghAMKAFNQEPEQCWECYSCVKICPQQAIECRHYADVVPMGASVQPLRGTDSIMWTIKFRNGNMKRFKF 80
Cdd:TIGR02060  29 LMHLDTE------IMKAYNIEPDMCWECYSCVKACPQGAIDVRGYADFAPLGGSCRPMRDEEKIMWTVKFRNGKVMRFKF 102

                          90
                  ....*....|....*...
gi 157804750   81 PIRTTPEGSIDPYGSKPE 98
Cdd:TIGR02060 103 PIRTTPWGSITPFEGVPE 120
APS-reductase_C pfam12139
Adenosine-5'-phosphosulfate reductase beta subunit; This family of proteins is found in ...
 43-98 3.48e-34

Adenosine-5'-phosphosulfate reductase beta subunit; This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 112 to 142 amino acids in length. This family is found in association with pfam00037, and has a conserved FPIRTT sequence motif. The whole beta subunit has the enzymic properties of EC:1.8.99.2.


Pssm-ID: 432356  Cd Length: 82  Bit Score: 113.65  E-value: 3.48e-34
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 157804750   43 RHYADVVPMGASVQPLRGTDSIMWTIKFRNGNMKRFKFPIRTTPEGSIDPYGSKPE 98
Cdd:pfam12139   2 RGYADFVPLGASVVPLRGSEDIMWTVKFRNGKVKRFKFPIRTTPEGSAIPLAGFPE 57
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 2-47 5.52e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 41.23  E-value: 5.52e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 157804750   2 MKLDNDGsetghaMKAFNQEPEQCWECYSCVKICPQQAIECRHYAD 47
Cdd:COG1146   25 LELDEEG------KKALVINPEECIGCGACELVCPVGAITVEDDEP 64
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 22-41 7.78e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 38.49  E-value: 7.78e-05
                         10        20
                 ....*....|....*....|
gi 157804750  22 PEQCWECYSCVKICPQQAIE 41
Cdd:COG4231   50 PDLCIGCGSCVQVCPVDAIK 69
Fer4_9 pfam13187
4Fe-4S dicluster domain;
17-40 8.25e-04

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 35.22  E-value: 8.25e-04
                          10        20
                  ....*....|....*....|....
gi 157804750   17 AFNQEPEQCWECYSCVKICPQQAI 40
Cdd:pfam13187  27 RGDIAGLACIGCGACVDACPRGAI 50
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
22-41 6.21e-03

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 33.17  E-value: 6.21e-03
                         10        20
                 ....*....|....*....|
gi 157804750  22 PEQCWECYSCVKICPQQAIE 41
Cdd:COG2768   39 PEKCIGCGACIEVCPVGAIK 58
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 22-41 9.40e-03

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 32.78  E-value: 9.40e-03
                         10        20
                 ....*....|....*....|
gi 157804750  22 PEQCWECYSCVKICPQQAIE 41
Cdd:COG1149   40 PDLCTGCGACVGVCPTGAIT 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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