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Conserved domains on  [gi|1574942|gb|AAB17510|]
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ribosomal protein L23a [Homo sapiens]

Protein Classification

uL23 family ribosomal protein( domain architecture ID 11488238)

uL23 family ribosomal protein is a component of the large ribosomal subunit.

Gene Ontology:  GO:0006412|GO:1904841|GO:0003735
PubMed:  8428950|8177742|24524803

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00191 PTZ00191
60S ribosomal protein L23a; Provisional
 36-156 1.24e-57

60S ribosomal protein L23a; Provisional


:

Pssm-ID: 185507 [Multi-domain]  Cd Length: 145  Bit Score: 176.43  E-value: 1.24e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    36 KKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIINFPLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKK 115
Cdd:PTZ00191  25 KKRKVRTSVRFFRPKTLRLPKKPKYPRRVKPASKKLDKYSIIKYPLTTEKAMKKIEDNNTLVFIVDQRANKTQIKKAVEK 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 1574942   116 LYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII 156
Cdd:PTZ00191 105 LYDVKVVKVNTLITPDGLKKAYIRLSPDVDALDVANKIGII 145
 
Name Accession Description Interval E-value
PTZ00191 PTZ00191
60S ribosomal protein L23a; Provisional
 36-156 1.24e-57

60S ribosomal protein L23a; Provisional


Pssm-ID: 185507 [Multi-domain]  Cd Length: 145  Bit Score: 176.43  E-value: 1.24e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    36 KKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIINFPLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKK 115
Cdd:PTZ00191  25 KKRKVRTSVRFFRPKTLRLPKKPKYPRRVKPASKKLDKYSIIKYPLTTEKAMKKIEDNNTLVFIVDQRANKTQIKKAVEK 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 1574942   116 LYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII 156
Cdd:PTZ00191 105 LYDVKVVKVNTLITPDGLKKAYIRLSPDVDALDVANKIGII 145
uL23_arch TIGR03636
ribosomal protein uL23, archaeal form; This model describes the archaeal ribosomal protein ...
 80-156 5.85e-31

ribosomal protein uL23, archaeal form; This model describes the archaeal ribosomal protein L23P and rigorously excludes the bacterial counterpart L23. In order to capture every known instance of archaeal L23P, the trusted cutoff is set lower than a few of the highest scoring eukaryotic cytosolic ribosomal counterparts. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274692  Cd Length: 77  Bit Score: 106.53  E-value: 5.85e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1574942     80 PLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII 156
Cdd:TIGR03636   1 PLVTEKAMNLIEKENKLTFIVDRRATKGDIKRAVEKLFDVKVEKVNTLITPRGEKKAYVKLAEEYSAEEIASRLGVF 77
Ribosomal_L23eN pfam03939
Ribosomal protein L23, N-terminal domain; The N-terminal domain appears to be specific to the ...
 31-66 1.45e-18

Ribosomal protein L23, N-terminal domain; The N-terminal domain appears to be specific to the eukaryotic ribosomal proteins L25, L23, and L23a.


Pssm-ID: 461099 [Multi-domain]  Cd Length: 50  Bit Score: 74.13  E-value: 1.45e-18
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1574942     31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAP 66
Cdd:pfam03939  15 GVHSHKKKKIRTSVTFHRPKTLRLARQPKYPRKSVP 50
RplW COG0089
Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L23 ...
 80-145 1.42e-16

Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L23 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439859  Cd Length: 88  Bit Score: 70.10  E-value: 1.42e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1574942   80 PLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRP-------------DGEKKAYVRLAPDYD 145
Cdd:COG0089   3 PVITEKSTALAEKNNKYTFEVAPDANKTEIKKAVEKLFGVKVEKVNTLNVKgkkkrfgrrvgkrSDWKKAIVTLAEGQK 81
 
Name Accession Description Interval E-value
PTZ00191 PTZ00191
60S ribosomal protein L23a; Provisional
 36-156 1.24e-57

60S ribosomal protein L23a; Provisional


Pssm-ID: 185507 [Multi-domain]  Cd Length: 145  Bit Score: 176.43  E-value: 1.24e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    36 KKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIINFPLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKK 115
Cdd:PTZ00191  25 KKRKVRTSVRFFRPKTLRLPKKPKYPRRVKPASKKLDKYSIIKYPLTTEKAMKKIEDNNTLVFIVDQRANKTQIKKAVEK 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 1574942   116 LYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII 156
Cdd:PTZ00191 105 LYDVKVVKVNTLITPDGLKKAYIRLSPDVDALDVANKIGII 145
PRK14548 PRK14548
50S ribosomal protein L23P; Provisional
 74-156 2.83e-34

50S ribosomal protein L23P; Provisional


Pssm-ID: 237750  Cd Length: 84  Bit Score: 114.95  E-value: 2.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    74 YAIINFPLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKI 153
Cdd:PRK14548   2 YSIIKYPLVTEKAMNLIEKENKLTFIVDRRATKPDIKRAVEELFDVKVEKVNTLITPKGEKKAYVKLAEEYDAEEIASRL 81


                 ...
gi 1574942   154 GII 156
Cdd:PRK14548  82 GVF 84
uL23_arch TIGR03636
ribosomal protein uL23, archaeal form; This model describes the archaeal ribosomal protein ...
 80-156 5.85e-31

ribosomal protein uL23, archaeal form; This model describes the archaeal ribosomal protein L23P and rigorously excludes the bacterial counterpart L23. In order to capture every known instance of archaeal L23P, the trusted cutoff is set lower than a few of the highest scoring eukaryotic cytosolic ribosomal counterparts. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274692  Cd Length: 77  Bit Score: 106.53  E-value: 5.85e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1574942     80 PLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII 156
Cdd:TIGR03636   1 PLVTEKAMNLIEKENKLTFIVDRRATKGDIKRAVEKLFDVKVEKVNTLITPRGEKKAYVKLAEEYSAEEIASRLGVF 77
Ribosomal_L23eN pfam03939
Ribosomal protein L23, N-terminal domain; The N-terminal domain appears to be specific to the ...
 31-66 1.45e-18

Ribosomal protein L23, N-terminal domain; The N-terminal domain appears to be specific to the eukaryotic ribosomal proteins L25, L23, and L23a.


Pssm-ID: 461099 [Multi-domain]  Cd Length: 50  Bit Score: 74.13  E-value: 1.45e-18
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1574942     31 GVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAP 66
Cdd:pfam03939  15 GVHSHKKKKIRTSVTFHRPKTLRLARQPKYPRKSVP 50
RplW COG0089
Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L23 ...
 80-145 1.42e-16

Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L23 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439859  Cd Length: 88  Bit Score: 70.10  E-value: 1.42e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1574942   80 PLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRP-------------DGEKKAYVRLAPDYD 145
Cdd:COG0089   3 PVITEKSTALAEKNNKYTFEVAPDANKTEIKKAVEKLFGVKVEKVNTLNVKgkkkrfgrrvgkrSDWKKAIVTLAEGQK 81
rplW PRK05738
50S ribosomal protein L23; Reviewed
 74-143 2.08e-16

50S ribosomal protein L23; Reviewed


Pssm-ID: 235586  Cd Length: 92  Bit Score: 69.73  E-value: 2.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    74 YAIINFPLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRP-------------DGEKKAYVRL 140
Cdd:PRK05738   1 YDVIKRPVITEKSTLLMEKQNKYVFEVAPDATKPEIKAAVEKLFGVKVESVNTLNVKgktkrfgrrigkrSDWKKAIVTL 80


                 ...
gi 1574942   141 APD 143
Cdd:PRK05738  81 AEG 83
Ribosomal_L23 pfam00276
Ribosomal protein L23;
80-145 2.10e-16

Ribosomal protein L23;


Pssm-ID: 459743  Cd Length: 86  Bit Score: 69.39  E-value: 2.10e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1574942     80 PLTTESAMKKIEDNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLI-------------RPDGEKKAYVRLAPDYD 145
Cdd:pfam00276   6 PVITEKSTALMEKNNKYTFEVDPDANKTEIKKAVEKLFGVKVEKVNTLNvkgkvkrfgrfvgRRSDWKKAIVTLAEGQK 84
rplW PRK12280
50S ribosomal protein L23; Reviewed
 71-145 2.17e-08

50S ribosomal protein L23; Reviewed


Pssm-ID: 237035 [Multi-domain]  Cd Length: 158  Bit Score: 50.14  E-value: 2.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    71 LDHYAIINFPLTTESAMKKIEDNnTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRP-------------DGEKKAY 137
Cdd:PRK12280   1 MNINEVIKKPILTEKSYSLMSKN-VYTFKVDRRANKIEIKKAVEFIFKVKVLKVNIFNVDkkpkrlgrfpgftNSYKKAY 79


                 ....*...
gi 1574942   138 VRLAPDYD 145
Cdd:PRK12280  80 VTLAEGYS 87
rpl23 CHL00030
ribosomal protein L23
 76-144 7.05e-05

ribosomal protein L23


Pssm-ID: 176971  Cd Length: 93  Bit Score: 39.52  E-value: 7.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1574942    76 IINFPLTTESAMKKIEdNNTLVFIVDVKANKHQISQAVKKLYDIDVAKVNTLIRPDGE-------------KKAYVRLAP 142
Cdd:CHL00030   3 GIKYPVFTDKSIRLLE-KNQYTFDVDSGSTKTEIKHWIELFFGVKVIAVNSHRLPRKKrrmgpimghkmhyKRMIITLQP 81


                 ..
gi 1574942   143 DY 144
Cdd:CHL00030  82 GY 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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