|
Name |
Accession |
Description |
Interval |
E-value |
| LamB |
smart00281 |
Laminin B domain; |
245-370 |
3.33e-41 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 147.41 E-value: 3.33e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 245 RLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVD--RGGRHPSAHDVILEGAGLRITAPLMplGKTLPCGLTK-TYTFRLNE 321
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDgrRGGTHVSAPDVILEGNGLRISHPAE--GPPLPDELTTvEVRFREEN 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 157419140 322 HPSNNWSPQLSYfEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARP 370
Cdd:smart00281 79 WQYYGGRPVTRE-DLMMVLANLTAILIRATYSQQMAGsRLSDVSLEVAVP 127
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
250-380 |
3.30e-37 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 136.25 E-value: 3.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 250 YFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAH---DVILEGAGLRITAPLMPLGKTLPcGLTKTYTFRLNEHpsnN 326
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNsepDVILEGNGLRLSYSSPDQPPPDP-GQEQTYSVRLHEE---N 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 327 W----SPQLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARP-VSGAPAPWVE 380
Cdd:pfam00052 77 WrdsdGAPVSREDFMMVLANLTAILIRATYSTGSGQvSLSNVSLDSAVPgGSGPPASWVE 136
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
614-1104 |
5.39e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 73.61 E-value: 5.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 614 NQVKIQMdqFMQQLQ-RMEALISKAQggdgvvpdTELEGRMQQAEQAlqdilrdaqisEGASRSLGLQLA----KVRSQE 688
Cdd:pfam15921 254 SQNKIEL--LLQQHQdRIEQLISEHE--------VEITGLTEKASSA-----------RSQANSIQSQLEiiqeQARNQN 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 689 NSYQSRLDDLKMTVERVRA----LGSQYQNRVRDTHRlitqmQLSLAESEASLGNTNipaSDHYVGPNGF------KSLA 758
Cdd:pfam15921 313 SMYMRQLSDLESTVSQLRSelreAKRMYEDKIEELEK-----QLVLANSELTEARTE---RDQFSQESGNlddqlqKLLA 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 759 QEATRLAESHVESASN-------------MEQLTRETEDYSK--QALSLVRKALHEGVgSGSGSPDGAVVQGLVEKLEKT 823
Cdd:pfam15921 385 DLHKREKELSLEKEQNkrlwdrdtgnsitIDHLRRELDDRNMevQRLEALLKAMKSEC-QGQMERQMAAIQGKNESLEKV 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 824 KSLAQQL--TREATQAEIEADRSYQHSLRlldsvSRLQGVSDQSFQVEEAKR-IKQKADSLSSLVTR------HMDEFKR 894
Cdd:pfam15921 464 SSLTAQLesTKEMLRKVVEELTAKKMTLE-----SSERTVSDLTASLQEKERaIEATNAEITKLRSRvdlklqELQHLKN 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 895 TQKNLGNWKEEAQQL-LQngKSGREKSDQLLSRA--NLAKSRAQEALSMGnatfyeveSILKNLREFDLQVDNRKAEAEE 971
Cdd:pfam15921 539 EGDHLRNVQTECEALkLQ--MAEKDKVIEILRQQieNMTQLVGQHGRTAG--------AMQVEKAQLEKEINDRRLELQE 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 972 aMKRLsyisqkvsdaSDKTQQAERALGSAAADAQRAK----NGAGEALEISSEIEQEIGSLNLEANVTadgalamEKGLA 1047
Cdd:pfam15921 609 -FKIL----------KDKKDAKIRELEARVSDLELEKvklvNAGSERLRAVKDIKQERDQLLNEVKTS-------RNELN 670
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 1048 SLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNagvtiqdTLNTLDG 1104
Cdd:pfam15921 671 SLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRN-------TLKSMEG 720
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
83-127 |
4.00e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 61.99 E-value: 4.00e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 157419140 83 PCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAG 127
Cdd:cd00055 1 PCDCNGHGSLSGQCDpGTGQCECKPNTTGRRCDRCAPGYYGLPSQG 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
84-128 |
1.03e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.40 E-value: 1.03e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 157419140 84 CNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGC 128
Cdd:smart00180 1 CDCDPGGSASGTCDpDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
139-184 |
2.38e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 59.67 E-value: 2.38e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 157419140 139 CDCDPAGIAGP-CDA--GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGC 184
Cdd:pfam00053 1 CDCNPHGSLSDtCDPetGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
84-123 |
2.55e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 59.67 E-value: 2.55e-11
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 157419140 84 CNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHML 123
Cdd:pfam00053 1 CDCNPHGSLSDTCDpETGQCLCKPGVTGRHCDRCKPGYYGL 41
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
516-565 |
2.68e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.59 E-value: 2.68e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 157419140 516 PCQCNNNvdPSASGNCDRLTGRCLkCIHNTAGIYCDQCKAGYFGDPLAPN 565
Cdd:cd00055 1 PCDCNGH--GSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGG 47
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
139-184 |
1.13e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 1.13e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 157419140 139 CDCDPAGIAGP-CDA--GRCVCKPAVTGERCDRCRSGYYnldGGNPEGC 184
Cdd:smart00180 1 CDCDPGGSASGtCDPdtGQCECKPNVTGRRCDRCAPGYY---GDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
517-564 |
1.39e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 54.67 E-value: 1.39e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 157419140 517 CQCNNNVdpSASGNCDRLTGRCLkCIHNTAGIYCDQCKAGYFGDPLAP 564
Cdd:pfam00053 1 CDCNPHG--SLSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDP 45
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
647-1064 |
6.08e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 6.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 647 TELEGRMQ----QAEQA-----LQDILRDAQISEGAS--RSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNR 715
Cdd:COG1196 196 GELERQLEplerQAEKAeryreLKEELKELEAELLLLklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 716 VRDTHRLITQMQLSLAESEASLGNTNipasdhyvgpNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK 795
Cdd:COG1196 276 LEELELELEEAQAEEYELLAELARLE----------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 796 ALHEgvgsgsgspdGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSvsrlqgvsdqsfQVEEAKRIK 875
Cdd:COG1196 346 LEEA----------EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA------------AAELAAQLE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 876 QKADSLSSLVTRhmdefkrtqknLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
Cdd:COG1196 404 ELEEAEEALLER-----------LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGsaaADAQRAKNGAGeALEISSEIEQEigslnlEANVT 1035
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL---LAGLRGLAGAV-AVLIGVEAAYE------AALEA 542
|
410 420
....*....|....*....|....*....
gi 157419140 1036 ADGALAMEKGLASLKSEMREVEGELERKE 1064
Cdd:COG1196 543 ALAAALQNIVVEDDEVAAAAIEYLKAAKA 571
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
139-185 |
7.24e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.74 E-value: 7.24e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 157419140 139 CDCDPAGIAGP-CDA--GRCVCKPAVTGERCDRCRSGYYNLDgGNPEGCT 185
Cdd:cd00055 2 CDCNGHGSLSGqCDPgtGQCECKPNTTGRRCDRCAPGYYGLP-SQGGGCQ 50
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
816-1082 |
5.08e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 5.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 816 LVEKLEKTKSLAQQLTREATQAEIEADRsYQHSLRLLDSvsRLQGVSDQ-SFQVEEAKRIKQKADSLSSLVTRHMDEFKR 894
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEE-LEEELEQLRK--ELEELSRQiSALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 895 TQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANlaksRAQEALSMGNATFYEVESILKNLREFDLQVDNRKA----EAE 970
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELTLLNEEAANLRERLEslerRIA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 971 EAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEanvtadgalamekgLASLK 1050
Cdd:TIGR02168 835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE--------------LEELS 900
|
250 260 270
....*....|....*....|....*....|....*
gi 157419140 1051 SEMREVE---GELERKELEFDTNMDAVQMVITEAQ 1082
Cdd:TIGR02168 901 EELRELEskrSELRRELEELREKLAQLELRLEGLE 935
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
517-561 |
1.32e-07 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 48.85 E-value: 1.32e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 157419140 517 CQCNnnVDPSASGNCDRLTGRCLkCIHNTAGIYCDQCKAGYFGDP 561
Cdd:smart00180 1 CDCD--PGGSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDG 42
|
|
| growth_prot_Scy |
NF041483 |
polarized growth protein Scy; |
760-1106 |
2.81e-07 |
|
polarized growth protein Scy;
Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 55.22 E-value: 2.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 760 EATRLAESHV-ESASNMEQLTRETEdysKQALSLVRKALHEGvgsgsgspDGAVVQGLVEKLEKTKSLAQQLTREATQAE 838
Cdd:NF041483 138 ERRQTVESHVnENVAWAEQLRARTE---SQARRLLDESRAEA--------EQALAAARAEAERLAEEARQRLGSEAESAR 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 839 IEAD----RSYQHSLRLLDSVS-RLQGVSDQSFQ-----VEEAKRIKQKADSLSSLVTRHMDEFKR--------TQKNLG 900
Cdd:NF041483 207 AEAEailrRARKDAERLLNAAStQAQEATDHAEQlrsstAAESDQARRQAAELSRAAEQRMQEAEEalrearaeAEKVVA 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 901 NWKEEAQQLLQNGKSGREKsdqllsRANLAKSR----AQEALSMGNATFYEVESILKNLREfdlQVDNRKAEAEEAmKRL 976
Cdd:NF041483 287 EAKEAAAKQLASAESANEQ------RTRTAKEEiarlVGEATKEAEALKAEAEQALADARA---EAEKLVAEAAEK-ART 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 977 SYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALE-ISSEIEQEIGSLNLEANVTADGAlameKGLA-------- 1047
Cdd:NF041483 357 VAAEDTAAQLAKAARTAEEVLTKASEDAKATTRAAAEEAErIRREAEAEADRLRGEAADQAEQL----KGAAkddtkeyr 432
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157419140 1048 ----SLKSEMREVEGELERKELEfdtnmdavqmVITEAQKVDTRAKNAGVT-IQDTLNTLDGLL 1106
Cdd:NF041483 433 aktvELQEEARRLRGEAEQLRAE----------AVAEGERIRGEARREAVQqIEEAARTAEELL 486
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
669-1099 |
2.01e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 52.27 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 669 ISEGASRSLGLQLAK----VRSQENSYQSRLDDLKMTVERVRALGSQYQnrvrDTHRLITqmqlslaESeaslgnTNIPA 744
Cdd:PRK04863 209 ISSAITRSLRDYLLPensgVRKAFQDMEAALRENRMTLEAIRVTQSDRD----LFKHLIT-------ES------TNYVA 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 745 SDHYVGPNGFKSLAQEATRL--------------AESHVESASNMEQLTRE----TEDY--SKQALSLVRKAL--HEGVG 802
Cdd:PRK04863 272 ADYMRHANERRVHLEEALELrrelytsrrqlaaeQYRLVEMARELAELNEAesdlEQDYqaASDHLNLVQTALrqQEKIE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 803 SGSGSpdgavVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLR----LLDSVSRLQGVSDQSFQVEEAKRIKQKA 878
Cdd:PRK04863 352 RYQAD-----LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDElksqLADYQQALDVQQTRAIQYQQAVQALERA 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 879 DSLSSLvtrhmDEFkrTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVE-SILKNL-R 956
Cdd:PRK04863 427 KQLCGL-----PDL--TADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSrSEAWDVaR 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 957 EFDLQVDNRKAEAEeamkRLSYISQKVSDA---SDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEAN 1033
Cdd:PRK04863 500 ELLRRLREQRHLAE----QLQQLRMRLSELeqrLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVS 575
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157419140 1034 VTADGALAMEKGLASLKSEMRevegELERKELEFDTNMDAVQMVitEAQKVDTRAKNAGVT--IQDTL 1099
Cdd:PRK04863 576 EARERRMALRQQLEQLQARIQ----RLAARAPAWLAAQDALARL--REQSGEEFEDSQDVTeyMQQLL 637
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
461-509 |
2.03e-06 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 45.81 E-value: 2.03e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 157419140 461 PCPCHNGFSCSVMPETEEVVCNnCPPGVTGARCELCADGYFGDPFGEHG 509
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
572-604 |
1.13e-05 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 43.50 E-value: 1.13e-05
10 20 30
....*....|....*....|....*....|....
gi 157419140 572 ACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
Cdd:cd00055 1 PCDCNGHGSLSGQCdPGTGQCECKPNTTGRRCDR 34
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
462-508 |
1.25e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 43.45 E-value: 1.25e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 157419140 462 CPCHNGFSCSVMPETEEVVCNnCPPGVTGARCELCADGYFGDPFGEH 508
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
573-604 |
4.12e-05 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 41.96 E-value: 4.12e-05
10 20 30
....*....|....*....|....*....|...
gi 157419140 573 CNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
Cdd:pfam00053 1 CDCNPHGSLSDTCdPETGQCLCKPGVTGRHCDR 33
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
573-604 |
8.57e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 41.14 E-value: 8.57e-05
10 20 30
....*....|....*....|....*....|...
gi 157419140 573 CNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEH 604
Cdd:smart00180 1 CDCDPGGSASGTCDPDtGQCECKPNVTGRRCDR 33
|
|
| growth_prot_Scy |
NF041483 |
polarized growth protein Scy; |
821-1091 |
2.30e-04 |
|
polarized growth protein Scy;
Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 45.59 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 821 EKTKSLAQQLTREATQAEIEADR---------------------SYQ-HSLRLLDSVSRLQGVSDQ--SFQVEEAKRIKQ 876
Cdd:NF041483 386 ATTRAAAEEAERIRREAEAEADRlrgeaadqaeqlkgaakddtkEYRaKTVELQEEARRLRGEAEQlrAEAVAEGERIRG 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 877 KAdslSSLVTRHMDEFKRTQKN-LGNWKEEAQQLLQNGKSGREK-SDQLLSRAN---------LAKSRAQ------EALS 939
Cdd:NF041483 466 EA---RREAVQQIEEAARTAEElLTKAKADADELRSTATAESERvRTEAIERATtlrrqaeetLERTRAEaerlraEAEE 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 940 MGNATFYEVESILKNLR-EFDLQVDNRKAEAEEAMKRLSyisqkvSDASDKTQQAERALGSAAADAQRAKNGAGEALE-- 1016
Cdd:NF041483 543 QAEEVRAAAERAARELReETERAIAARQAEAAEELTRLH------TEAEERLTAAEEALADARAEAERIRREAAEETErl 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 1017 ----------ISSEIEQEIGSLNLEANVTADGALAMEKGLA-SLKSemrEVEGELERKELEFDTNMDAVQM-VITEAQKV 1084
Cdd:NF041483 617 rteaaerirtLQAQAEQEAERLRTEAAADASAARAEGENVAvRLRS---EAAAEAERLKSEAQESADRVRAeAAAAAERV 693
|
....*..
gi 157419140 1085 DTRAKNA 1091
Cdd:NF041483 694 GTEAAEA 700
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
484-509 |
3.56e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 36.56 E-value: 3.56e-03
10 20
....*....|....*....|....*.
gi 157419140 484 CPPGVTGARCELCADGYFGDPFGEHG 509
Cdd:pfam00053 22 CKPGVTGRHCDRCKPGYYGLPSDPPQ 47
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
891-1109 |
3.97e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 40.12 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 891 EFKRTQKNLGNWKEEAQQLLQNGKSGREKSdqllsranlaksraqealsmgnatfyEVESILKNLREFDLQVDNRK---- 966
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLE--------------------------SVEALLKKHEALEAELAAHEerve 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 967 ---AEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLN-LEANVTADGALAM 1042
Cdd:cd00176 58 alnELGEQLIEEGHPDAEEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEeKEAALASEDLGKD 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 1043 EKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAgvTIQDTLNTLDGLLHLM 1109
Cdd:cd00176 138 LESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEE--KLEELNERWEELLELA 202
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
28-78 |
7.56e-03 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 35.79 E-value: 7.56e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 157419140 28 CDCNG---KSRQCifdrelHRQTGngfRCLnCNDNTDGIHCEKCKNGFYRHRER 78
Cdd:cd00055 2 CDCNGhgsLSGQC------DPGTG---QCE-CKPNTTGRRCDRCAPGYYGLPSQ 45
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
28-86 |
8.47e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 35.41 E-value: 8.47e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157419140 28 CDCNG---KSRQCifdrelHRQTGngfRCLnCNDNTDGIHCEKCKNGFYRHRerdRCLPCNC 86
Cdd:pfam00053 1 CDCNPhgsLSDTC------DPETG---QCL-CKPGVTGRHCDRCKPGYYGLP---SDPPQGC 49
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LamB |
smart00281 |
Laminin B domain; |
245-370 |
3.33e-41 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 147.41 E-value: 3.33e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 245 RLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVD--RGGRHPSAHDVILEGAGLRITAPLMplGKTLPCGLTK-TYTFRLNE 321
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDgrRGGTHVSAPDVILEGNGLRISHPAE--GPPLPDELTTvEVRFREEN 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 157419140 322 HPSNNWSPQLSYfEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARP 370
Cdd:smart00281 79 WQYYGGRPVTRE-DLMMVLANLTAILIRATYSQQMAGsRLSDVSLEVAVP 127
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
250-380 |
3.30e-37 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 136.25 E-value: 3.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 250 YFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAH---DVILEGAGLRITAPLMPLGKTLPcGLTKTYTFRLNEHpsnN 326
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNsepDVILEGNGLRLSYSSPDQPPPDP-GQEQTYSVRLHEE---N 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 327 W----SPQLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARP-VSGAPAPWVE 380
Cdd:pfam00052 77 WrdsdGAPVSREDFMMVLANLTAILIRATYSTGSGQvSLSNVSLDSAVPgGSGPPASWVE 136
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
614-1104 |
5.39e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 73.61 E-value: 5.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 614 NQVKIQMdqFMQQLQ-RMEALISKAQggdgvvpdTELEGRMQQAEQAlqdilrdaqisEGASRSLGLQLA----KVRSQE 688
Cdd:pfam15921 254 SQNKIEL--LLQQHQdRIEQLISEHE--------VEITGLTEKASSA-----------RSQANSIQSQLEiiqeQARNQN 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 689 NSYQSRLDDLKMTVERVRA----LGSQYQNRVRDTHRlitqmQLSLAESEASLGNTNipaSDHYVGPNGF------KSLA 758
Cdd:pfam15921 313 SMYMRQLSDLESTVSQLRSelreAKRMYEDKIEELEK-----QLVLANSELTEARTE---RDQFSQESGNlddqlqKLLA 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 759 QEATRLAESHVESASN-------------MEQLTRETEDYSK--QALSLVRKALHEGVgSGSGSPDGAVVQGLVEKLEKT 823
Cdd:pfam15921 385 DLHKREKELSLEKEQNkrlwdrdtgnsitIDHLRRELDDRNMevQRLEALLKAMKSEC-QGQMERQMAAIQGKNESLEKV 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 824 KSLAQQL--TREATQAEIEADRSYQHSLRlldsvSRLQGVSDQSFQVEEAKR-IKQKADSLSSLVTR------HMDEFKR 894
Cdd:pfam15921 464 SSLTAQLesTKEMLRKVVEELTAKKMTLE-----SSERTVSDLTASLQEKERaIEATNAEITKLRSRvdlklqELQHLKN 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 895 TQKNLGNWKEEAQQL-LQngKSGREKSDQLLSRA--NLAKSRAQEALSMGnatfyeveSILKNLREFDLQVDNRKAEAEE 971
Cdd:pfam15921 539 EGDHLRNVQTECEALkLQ--MAEKDKVIEILRQQieNMTQLVGQHGRTAG--------AMQVEKAQLEKEINDRRLELQE 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 972 aMKRLsyisqkvsdaSDKTQQAERALGSAAADAQRAK----NGAGEALEISSEIEQEIGSLNLEANVTadgalamEKGLA 1047
Cdd:pfam15921 609 -FKIL----------KDKKDAKIRELEARVSDLELEKvklvNAGSERLRAVKDIKQERDQLLNEVKTS-------RNELN 670
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 1048 SLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNagvtiqdTLNTLDG 1104
Cdd:pfam15921 671 SLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRN-------TLKSMEG 720
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
83-127 |
4.00e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 61.99 E-value: 4.00e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 157419140 83 PCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAG 127
Cdd:cd00055 1 PCDCNGHGSLSGQCDpGTGQCECKPNTTGRRCDRCAPGYYGLPSQG 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
84-128 |
1.03e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.40 E-value: 1.03e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 157419140 84 CNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGC 128
Cdd:smart00180 1 CDCDPGGSASGTCDpDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
139-184 |
2.38e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 59.67 E-value: 2.38e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 157419140 139 CDCDPAGIAGP-CDA--GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGC 184
Cdd:pfam00053 1 CDCNPHGSLSDtCDPetGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
84-123 |
2.55e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 59.67 E-value: 2.55e-11
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 157419140 84 CNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHML 123
Cdd:pfam00053 1 CDCNPHGSLSDTCDpETGQCLCKPGVTGRHCDRCKPGYYGL 41
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
516-565 |
2.68e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.59 E-value: 2.68e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 157419140 516 PCQCNNNvdPSASGNCDRLTGRCLkCIHNTAGIYCDQCKAGYFGDPLAPN 565
Cdd:cd00055 1 PCDCNGH--GSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGG 47
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
614-1075 |
7.37e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 63.60 E-value: 7.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 614 NQVKIQMDQFMQQLQRMEALISKAQggdgvvpdTELEGRMQQAEQALQdilrdaqiseGASRSLglqlAKVRSQENSYQS 693
Cdd:pfam15921 415 DHLRRELDDRNMEVQRLEALLKAMK--------SECQGQMERQMAAIQ----------GKNESL----EKVSSLTAQLES 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 694 RLDDLKMTVERVRALGSQYQNrvrdTHRLITQMQLSLAESEASLGNTNIPA----SDHYVGPNGFKSLAQEATRLaeSHV 769
Cdd:pfam15921 473 TKEMLRKVVEELTAKKMTLES----SERTVSDLTASLQEKERAIEATNAEItklrSRVDLKLQELQHLKNEGDHL--RNV 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 770 ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSgSGSPDGAVvqgLVEKLEKTKSLAQQlTREATQAEIEADRSyQHSL 849
Cdd:pfam15921 547 QTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-HGRTAGAM---QVEKAQLEKEINDR-RLELQEFKILKDKK-DAKI 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 850 RLLDS------VSRLQGVSDQSFQVEEAKRIKQKADSLsslvtrhMDEFKRTQKNLGNWKEEAQQLLQNGksgREKSDQL 923
Cdd:pfam15921 621 RELEArvsdleLEKVKLVNAGSERLRAVKDIKQERDQL-------LNEVKTSRNELNSLSEDYEVLKRNF---RNKSEEM 690
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 924 LSRANLAKSRAQEALSmgnatfyEVESILKNLREFDlQVDNRKAEAEEAM-KRLSYISQKVSDASDKTQQAERALGSAAA 1002
Cdd:pfam15921 691 ETTTNKLKMQLKSAQS-------ELEQTRNTLKSME-GSDGHAMKVAMGMqKQITAKRGQIDALQSKIQFLEEAMTNANK 762
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157419140 1003 DAQRAKngagealEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
Cdd:pfam15921 763 EKHFLK-------EEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
139-184 |
1.13e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 1.13e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 157419140 139 CDCDPAGIAGP-CDA--GRCVCKPAVTGERCDRCRSGYYnldGGNPEGC 184
Cdd:smart00180 1 CDCDPGGSASGtCDPdtGQCECKPNVTGRRCDRCAPGYY---GDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
517-564 |
1.39e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 54.67 E-value: 1.39e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 157419140 517 CQCNNNVdpSASGNCDRLTGRCLkCIHNTAGIYCDQCKAGYFGDPLAP 564
Cdd:pfam00053 1 CDCNPHG--SLSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDP 45
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
647-1064 |
6.08e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 6.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 647 TELEGRMQ----QAEQA-----LQDILRDAQISEGAS--RSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNR 715
Cdd:COG1196 196 GELERQLEplerQAEKAeryreLKEELKELEAELLLLklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 716 VRDTHRLITQMQLSLAESEASLGNTNipasdhyvgpNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK 795
Cdd:COG1196 276 LEELELELEEAQAEEYELLAELARLE----------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 796 ALHEgvgsgsgspdGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSvsrlqgvsdqsfQVEEAKRIK 875
Cdd:COG1196 346 LEEA----------EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA------------AAELAAQLE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 876 QKADSLSSLVTRhmdefkrtqknLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
Cdd:COG1196 404 ELEEAEEALLER-----------LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGsaaADAQRAKNGAGeALEISSEIEQEigslnlEANVT 1035
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL---LAGLRGLAGAV-AVLIGVEAAYE------AALEA 542
|
410 420
....*....|....*....|....*....
gi 157419140 1036 ADGALAMEKGLASLKSEMREVEGELERKE 1064
Cdd:COG1196 543 ALAAALQNIVVEDDEVAAAAIEYLKAAKA 571
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
139-185 |
7.24e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.74 E-value: 7.24e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 157419140 139 CDCDPAGIAGP-CDA--GRCVCKPAVTGERCDRCRSGYYNLDgGNPEGCT 185
Cdd:cd00055 2 CDCNGHGSLSGqCDPgtGQCECKPNTTGRRCDRCAPGYYGLP-SQGGGCQ 50
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
816-1082 |
5.08e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 5.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 816 LVEKLEKTKSLAQQLTREATQAEIEADRsYQHSLRLLDSvsRLQGVSDQ-SFQVEEAKRIKQKADSLSSLVTRHMDEFKR 894
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEE-LEEELEQLRK--ELEELSRQiSALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 895 TQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANlaksRAQEALSMGNATFYEVESILKNLREFDLQVDNRKA----EAE 970
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELTLLNEEAANLRERLEslerRIA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 971 EAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEanvtadgalamekgLASLK 1050
Cdd:TIGR02168 835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE--------------LEELS 900
|
250 260 270
....*....|....*....|....*....|....*
gi 157419140 1051 SEMREVE---GELERKELEFDTNMDAVQMVITEAQ 1082
Cdd:TIGR02168 901 EELRELEskrSELRRELEELREKLAQLELRLEGLE 935
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
648-1099 |
1.10e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.93 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDILRDAQISEGASRSLGL--QLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDthrlITQ 725
Cdd:COG4717 99 ELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPERLEELEERLEELRELEEELEELEAE----LAE 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 726 MQLSLAESEASLGNTNipasdhyvgPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEgvgsgs 805
Cdd:COG4717 175 LQEELEELLEQLSLAT---------EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA------ 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 806 gspdgavvqglvEKLEKTKSLAQQLTREATQAEIEADrsyqhSLRLLDSVSRLQGVsdqsfqveeakrikqkADSLSSLV 885
Cdd:COG4717 240 ------------ALEERLKEARLLLLIAAALLALLGL-----GGSLLSLILTIAGV----------------LFLVLGLL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 886 TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSR----ANLAKSRAQEALSMGNATFYEVESILKNLREFDLQ 961
Cdd:COG4717 287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAlglpPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 962 V---------DNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAleissEIEQEIGSLNLEA 1032
Cdd:COG4717 367 EleqeiaallAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE-----ELEEELEELEEEL 441
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157419140 1033 NVTADGALAMEKGLASLKSEMREVE--GELERKELEFDTnmdaVQMVITEAQKVDTRAKNAGVTIQDTL 1099
Cdd:COG4717 442 EELEEELEELREELAELEAELEQLEedGELAELLQELEE----LKAELRELAEEWAALKLALELLEEAR 506
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
752-1039 |
1.17e-07 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 55.73 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 752 NGFKSL--AQEATRLAESHVESASNMEQLTRETEDYSKQaLSLVRKALHEGVGSGSGSpdgavVQGLVEKLEKTKSLAQQ 829
Cdd:COG5185 347 QGQESLteNLEAIKEEIENIVGEVELSKSSEELDSFKDT-IESTKESLDEIPQNQRGY-----AQEILATLEDTLKAADR 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 830 lTREATQAEIE-ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSlvtrhmdefkRTQKNLGNWKEEAQQ 908
Cdd:COG5185 421 -QIEELQRQIEqATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINR----------SVRSKKEDLNEELTQ 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 909 LLQNGKSGREKSDQLlsRANLAKSraqealsmgnatfyeVESILKNLREFDLQVDNRKAEAEEAMKRLsyISQKVSDASD 988
Cdd:COG5185 490 IESRVSTLKATLEKL--RAKLERQ---------------LEGVRSKLDQVAESLKDFMRARGYAHILA--LENLIPASEL 550
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 157419140 989 KTQQAERALGSAAADAQRAKNGAGEALEIsseieqeIGSLNLEANVTADGA 1039
Cdd:COG5185 551 IQASNAKTDGQAANLRTAVIDELTQYLST-------IESQQAREDPIPDQA 594
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
517-561 |
1.32e-07 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 48.85 E-value: 1.32e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 157419140 517 CQCNnnVDPSASGNCDRLTGRCLkCIHNTAGIYCDQCKAGYFGDP 561
Cdd:smart00180 1 CDCD--PGGSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDG 42
|
|
| growth_prot_Scy |
NF041483 |
polarized growth protein Scy; |
760-1106 |
2.81e-07 |
|
polarized growth protein Scy;
Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 55.22 E-value: 2.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 760 EATRLAESHV-ESASNMEQLTRETEdysKQALSLVRKALHEGvgsgsgspDGAVVQGLVEKLEKTKSLAQQLTREATQAE 838
Cdd:NF041483 138 ERRQTVESHVnENVAWAEQLRARTE---SQARRLLDESRAEA--------EQALAAARAEAERLAEEARQRLGSEAESAR 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 839 IEAD----RSYQHSLRLLDSVS-RLQGVSDQSFQ-----VEEAKRIKQKADSLSSLVTRHMDEFKR--------TQKNLG 900
Cdd:NF041483 207 AEAEailrRARKDAERLLNAAStQAQEATDHAEQlrsstAAESDQARRQAAELSRAAEQRMQEAEEalrearaeAEKVVA 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 901 NWKEEAQQLLQNGKSGREKsdqllsRANLAKSR----AQEALSMGNATFYEVESILKNLREfdlQVDNRKAEAEEAmKRL 976
Cdd:NF041483 287 EAKEAAAKQLASAESANEQ------RTRTAKEEiarlVGEATKEAEALKAEAEQALADARA---EAEKLVAEAAEK-ART 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 977 SYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALE-ISSEIEQEIGSLNLEANVTADGAlameKGLA-------- 1047
Cdd:NF041483 357 VAAEDTAAQLAKAARTAEEVLTKASEDAKATTRAAAEEAErIRREAEAEADRLRGEAADQAEQL----KGAAkddtkeyr 432
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157419140 1048 ----SLKSEMREVEGELERKELEfdtnmdavqmVITEAQKVDTRAKNAGVT-IQDTLNTLDGLL 1106
Cdd:NF041483 433 aktvELQEEARRLRGEAEQLRAE----------AVAEGERIRGEARREAVQqIEEAARTAEELL 486
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
648-1036 |
2.99e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 54.14 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDILRDAQISEgasRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ 727
Cdd:COG4372 17 GLRPKTGILIAALSEQLRKALFEL---DKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 728 LSLAESEASLgntnipasdhyvgpngfKSLAQEATRLAEShvesasnMEQLTREtedysKQALSLVRKALHEGVgsgsgs 807
Cdd:COG4372 94 AELAQAQEEL-----------------ESLQEEAEELQEE-------LEELQKE-----RQDLEQQRKQLEAQI------ 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 808 pdGAVVQGLVEKLEKTKSLAQQLTReaTQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTR 887
Cdd:COG4372 139 --AELQSEIAEREEELKELEEQLES--LQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPR 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 888 HMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFD----LQVD 963
Cdd:COG4372 215 ELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEaleeAALE 294
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157419140 964 NRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAAD--AQRAKNGAGEALEISSEIEQEIGSLNLEANVTA 1036
Cdd:COG4372 295 LKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAIllAELADLLQLLLVGLLDNDVLELLSKGAEAGVAD 369
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
816-1089 |
4.60e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 4.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 816 LVEKLEKTKSLAQQLTRE---------ATQAEIEADRSYQHSL--RLLDSVSRLQG-VSDQSFQVEEAKRIKQKADSLSs 883
Cdd:TIGR02168 237 LREELEELQEELKEAEEEleeltaelqELEEKLEELRLEVSELeeEIEELQKELYAlANEISRLEQQKQILRERLANLE- 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 884 lvtrhmDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEAlsmgNATFYEVESILKNLREFDLQVD 963
Cdd:TIGR02168 316 ------RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL----EAELEELESRLEELEEQLETLR 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 964 NRKAEAEE----AMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAkngagEALEISSEIEQEigslnleanvtadga 1039
Cdd:TIGR02168 386 SKVAQLELqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-----ELKELQAELEEL--------------- 445
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 157419140 1040 lamEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAK 1089
Cdd:TIGR02168 446 ---EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
828-1091 |
8.00e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 8.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 828 QQLTREATQAEiEAdRSYQHSLRLLDSvsRLQGVSDQSFQvEEAKRIKQKADSLSSLvtrhmdefkrtqknlgnwKEEAQ 907
Cdd:COG1196 203 EPLERQAEKAE-RY-RELKEELKELEA--ELLLLKLRELE-AELEELEAELEELEAE------------------LEELE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 908 QLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLsyiSQKVSDAS 987
Cdd:COG1196 260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL---EEELEELE 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 988 DKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEF 1067
Cdd:COG1196 337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416
|
250 260
....*....|....*....|....
gi 157419140 1068 DTNMDAVQMVITEAQKVDTRAKNA 1091
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEE 440
|
|
| PspA_IM30 |
pfam04012 |
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ... |
851-1062 |
1.41e-06 |
|
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 50.45 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 851 LLDSVSRL--QGVSDQSFQVEEAKRIKQKAdslsslvTRHMdefkrtQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRAN 928
Cdd:pfam04012 1 IFKRLGRLvrANIHEGLDKAEDPEKMLEQA-------IRDM------QSELVKARQALAQTIARQKQLERRLEQQTEQAK 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 929 LAKSRAQEALSMGN-----ATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQ----QAERALGS 999
Cdd:pfam04012 68 KLEEKAQAALTKGNeelarEALAEKKSLEKQAEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNllkaRLKAAKAQ 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 1000 AAADAQRAKNGAGEALEISSEIEQEIgsLNLEANVTADGALAMEKGL----ASLKSEMREVEGELER 1062
Cdd:pfam04012 148 EAVQTSLGSLSTSSATDSFERIEEKI--EEREARADAAAELASAVDLdaklEQAGIQMEVSEDVLAR 212
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
669-1099 |
2.01e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 52.27 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 669 ISEGASRSLGLQLAK----VRSQENSYQSRLDDLKMTVERVRALGSQYQnrvrDTHRLITqmqlslaESeaslgnTNIPA 744
Cdd:PRK04863 209 ISSAITRSLRDYLLPensgVRKAFQDMEAALRENRMTLEAIRVTQSDRD----LFKHLIT-------ES------TNYVA 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 745 SDHYVGPNGFKSLAQEATRL--------------AESHVESASNMEQLTRE----TEDY--SKQALSLVRKAL--HEGVG 802
Cdd:PRK04863 272 ADYMRHANERRVHLEEALELrrelytsrrqlaaeQYRLVEMARELAELNEAesdlEQDYqaASDHLNLVQTALrqQEKIE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 803 SGSGSpdgavVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLR----LLDSVSRLQGVSDQSFQVEEAKRIKQKA 878
Cdd:PRK04863 352 RYQAD-----LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDElksqLADYQQALDVQQTRAIQYQQAVQALERA 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 879 DSLSSLvtrhmDEFkrTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVE-SILKNL-R 956
Cdd:PRK04863 427 KQLCGL-----PDL--TADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSrSEAWDVaR 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 957 EFDLQVDNRKAEAEeamkRLSYISQKVSDA---SDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEAN 1033
Cdd:PRK04863 500 ELLRRLREQRHLAE----QLQQLRMRLSELeqrLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVS 575
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157419140 1034 VTADGALAMEKGLASLKSEMRevegELERKELEFDTNMDAVQMVitEAQKVDTRAKNAGVT--IQDTL 1099
Cdd:PRK04863 576 EARERRMALRQQLEQLQARIQ----RLAARAPAWLAAQDALARL--REQSGEEFEDSQDVTeyMQQLL 637
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
461-509 |
2.03e-06 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 45.81 E-value: 2.03e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 157419140 461 PCPCHNGFSCSVMPETEEVVCNnCPPGVTGARCELCADGYFGDPFGEHG 509
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
648-996 |
2.24e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.98 E-value: 2.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDiLRDAQisegasRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ 727
Cdd:TIGR02168 688 ELEEKIAELEKALAE-LRKEL------EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 728 LSLAESEAslgntnipasdhyvgpngfkSLAQEATRLAESHVESASNMEQLTRETEDYS--KQALSLVRKALHEgvgsgs 805
Cdd:TIGR02168 761 AEIEELEE--------------------RLEEAEEELAEAEAEIEELEAQIEQLKEELKalREALDELRAELTL------ 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 806 gspdgavvqgLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGV--------SDQSFQVEEAKRIKQK 877
Cdd:TIGR02168 815 ----------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieeleeliEELESELEALLNERAS 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLRE 957
Cdd:TIGR02168 885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 157419140 958 FDLQVDNRK-------------------AEAEEAMKRLSYISQKVSDASDKTQQAERA 996
Cdd:TIGR02168 965 DDEEEARRRlkrlenkikelgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
|
|
| DUF4175 |
pfam13779 |
Domain of unknown function (DUF4175); |
755-1065 |
7.16e-06 |
|
Domain of unknown function (DUF4175);
Pssm-ID: 463981 [Multi-domain] Cd Length: 833 Bit Score: 50.37 E-value: 7.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 755 KSLAQEATRLA---ESHVESASNMEQLTRETEDYSKQA---LSLvRKALHEGVGSGSGSPDGAVVQGLVEklektksLAQ 828
Cdd:pfam13779 406 RALIEQRRRLAldrENRPRVARALDALTLAPEEFGPDAgvyLGL-RSALARLELARSDEALDEVADLLWE-------LAL 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 829 QLT-REATQAEIEADRSYQhslRLLDSVSRlqGVSDqsfqvEEakrIKQKADSLSSLVTRHMDEFKRTQKNLGNwkEEAQ 907
Cdd:pfam13779 478 RIEdGDLSDAERRLRAAQE---RLSEALER--GASD-----EE---IAKLMQELREALDDYMQALAEQAQQNPQ--DLQQ 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 908 QLLQNGKSGREKS-DQLLSR-ANLAKS----RAQEALSmgnatfyEVESILKNLR--EFDLQVDNRKAEAEEAMKRLSYI 979
Cdd:pfam13779 543 PDDPNAQEMTQQDlQRMLDRiEELARSgrraEAQQMLS-------QLQQMLENLQagQPQQQQQQGQSEMQQAMDELGDL 615
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 980 SQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGAL-----AMEKGLASLKSEMR 1054
Cdd:pfam13779 616 LREQQQLLDETFRQLQQQGGQQQGQPGQQGQQGQGQQPGQGGQQPGAQMPPQGGAEALGDLaerqqALRRRLEELQDELK 695
|
330
....*....|.
gi 157419140 1055 EVEGELERKEL 1065
Cdd:pfam13779 696 ELGGKEPGQAL 706
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
572-604 |
1.13e-05 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 43.50 E-value: 1.13e-05
10 20 30
....*....|....*....|....*....|....
gi 157419140 572 ACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
Cdd:cd00055 1 PCDCNGHGSLSGQCdPGTGQCECKPNTTGRRCDR 34
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
614-1067 |
1.14e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 614 NQVKIQMDQFMQQLQRMEALISkAQGGDGVvpdTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQS 693
Cdd:COG4913 312 ERLEARLDALREELDELEAQIR-GNGGDRL---EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 694 RLDDLKMTVERVRAlgsQYQNRVRDTHRLITQMQLSLAESE---ASL--GNTNIPASDHYVgpngfKSLAQEATRLAESH 768
Cdd:COG4913 388 EAAALLEALEEELE---ALEEALAEAEAALRDLRRELRELEaeiASLerRKSNIPARLLAL-----RDALAEALGLDEAE 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 769 V----------------ESAsnMEQLTR--------ETEDYsKQALSLVRkALH-------EGVGSGSGSPDGAVV--QG 815
Cdd:COG4913 460 LpfvgelievrpeeerwRGA--IERVLGgfaltllvPPEHY-AAALRWVN-RLHlrgrlvyERVRTGLPDPERPRLdpDS 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 816 LVEKLEKTKSLAqqltREATQAEIEADRSYqhslRLLDSVSRLQGVS-------------------DQSFQVEE------ 870
Cdd:COG4913 536 LAGKLDFKPHPF----RAWLEAELGRRFDY----VCVDSPEELRRHPraitragqvkgngtrhekdDRRRIRSRyvlgfd 607
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 871 -AKRIKQKADSLSSLvTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQ-----EALSMGNAT 944
Cdd:COG4913 608 nRAKLAALEAELAEL-EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAEleaelERLDASSDD 686
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 945 fyevesiLKNLREfdlQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAknGAGEALEISSEIEQE 1024
Cdd:COG4913 687 -------LAALEE---QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA--EDLARLELRALLEER 754
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 157419140 1025 IGSLNLEAnVTADGALAMEKGLASLKSEMREVEGELERKELEF 1067
Cdd:COG4913 755 FAAALGDA-VERELRENLEERIDALRARLNRAEEELERAMRAF 796
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
462-508 |
1.25e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 43.45 E-value: 1.25e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 157419140 462 CPCHNGFSCSVMPETEEVVCNnCPPGVTGARCELCADGYFGDPFGEH 508
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| TNFRSF4 |
cd13406 |
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134 or OXO40; ... |
437-517 |
1.35e-05 |
|
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134 or OXO40; TNFRSF4 (also known as OX40, ACT35, CD134, IMD16, TXGP1L) activates NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. It also promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. It is primarily expressed on activated CD4+ and CD8+ T cells, where it is transiently expressed and upregulated on the most recently antigen-activated T cells within inflammatory lesions. This makes it an attractive target to modulate immune responses, i.e. TNFRSF4 (OX40) blocking agents to inhibit adverse inflammation or agonists to enhance immune responses. An artificially created biologic fusion protein, OX40-immunoglobulin (OX40-Ig), prevents OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Some single nucleotide polymorphisms (SNPs) of its natural ligand OX40 ligand (OX40L, CD252), which is also found on activated T cells, have been associated with systemic lupus erythematosus.
Pssm-ID: 276911 [Multi-domain] Cd Length: 142 Bit Score: 46.24 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPE----TEEVVCnNCPPGVT-------GARCELCADGYFGDpf 505
Cdd:cd13406 31 TQDTVCSPCEPGFYNEAVNYEPCKPCTQCNQRSGSEEKQkctkTSDTVC-RCRPGTQpldsykpGVDCVPCPPGHFSR-- 107
|
90
....*....|..
gi 157419140 506 GEHGPVRPCQPC 517
Cdd:cd13406 108 GDNQACKPWTNC 119
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
648-1066 |
2.64e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.52 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDILRdaQISEGAS--RSLGLQLAKVRSQensYQsRLDDLKMTVERVRALGSQYQNRVRDTHRLITQ 725
Cdd:PRK03918 190 NIEELIKEKEKELEEVLR--EINEISSelPELREELEKLEKE---VK-ELEELKEEIEELEKELESLEGSKRKLEEKIRE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 726 MQLSLAESEASLgntnipasdhyvgpngfKSLAQEATRLAESHvESASNMEQLTRETEDYsKQALSLVRKALhegvgsGS 805
Cdd:PRK03918 264 LEERIEELKKEI-----------------EELEEKVKELKELK-EKAEEYIKLSEFYEEY-LDELREIEKRL------SR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 806 GSPDGAVVQGLVEKLEKTKSLAQQLTREATQ-----AEIEAD-RSYQHSLRLLDSVSRLQgvsdQSFQVEEAKRIKQKAD 879
Cdd:PRK03918 319 LEEEINGIEERIKELEEKEERLEELKKKLKElekrlEELEERhELYEEAKAKKEELERLK----KRLTGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 880 SLSSLVTRHMDEFKRTQKNLGNWKEEAQQL------LQNGKS-----GREKSDQllSRANL-AKSRAqealsmgnatfyE 947
Cdd:PRK03918 395 ELEKAKEEIEEEISKITARIGELKKEIKELkkaieeLKKAKGkcpvcGRELTEE--HRKELlEEYTA------------E 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 948 VESILKNLREFDLQVDNRKAEAEEAMKRLSYISQ--KVSDASDKTQQAERALGS-AAADAQRAKNGAGEALEISSEIEQE 1024
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGE 540
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 157419140 1025 IGSLNLEANVTADgalaMEKGLASLKSEMREVEGELER--KELE 1066
Cdd:PRK03918 541 IKSLKKELEKLEE----LKKKLAELEKKLDELEEELAEllKELE 580
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
890-1061 |
3.42e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.59 E-value: 3.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 890 DEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEA 969
Cdd:COG4372 45 EELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKER 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 970 EEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAgEALEIS------SEIEQEIGSLNLEANVTADGALAME 1043
Cdd:COG4372 125 QDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEEL-AALEQElqalseAEAEQALDELLKEANRNAEKEEELA 203
|
170
....*....|....*...
gi 157419140 1044 KGLASLKSEMREVEGELE 1061
Cdd:COG4372 204 EAEKLIESLPRELAEELL 221
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
648-1087 |
3.96e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.01 E-value: 3.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ 727
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 728 LSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVgsgsgS 807
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL-----A 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 808 PDGAVVQGLVEKLEKT------KSLAQQLTREATQAE--IEADRSyqhslRLLDSVSRLQGVSDQSFQVEEAKRIKQKAD 879
Cdd:COG1196 524 GAVAVLIGVEAAYEAAleaalaAALQNIVVEDDEVAAaaIEYLKA-----AKAGRATFLPLDKIRARAALAAALARGAIG 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 880 SLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRAnLAKSRAQEALSMGNATFYEVESILKNLREFd 959
Cdd:COG1196 599 AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL-REVTLEGEGGSAGGSLTGGSRRELLAALLE- 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 960 lqvdnRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNgAGEALEISSEIEQEIGSLNLEANVTADGA 1039
Cdd:COG1196 677 -----AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAEREELLEELLEEEELLEE 750
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 157419140 1040 LAMEKGLASLKSEmrEVEGELERKELEFDT----NMDAvqmvITEAQKVDTR 1087
Cdd:COG1196 751 EALEELPEPPDLE--ELERELERLEREIEAlgpvNLLA----IEEYEELEER 796
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
573-604 |
4.12e-05 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 41.96 E-value: 4.12e-05
10 20 30
....*....|....*....|....*....|...
gi 157419140 573 CNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
Cdd:pfam00053 1 CDCNPHGSLSDTCdPETGQCLCKPGVTGRHCDR 33
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
809-1100 |
4.63e-05 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 47.30 E-value: 4.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 809 DGAVVQGLVEKLEKTKSLAQQLTreaTQAEIEADrsyqhslrllDSVSRLQGVSDQSFQ-VEEAKRIKQKADslsslvtr 887
Cdd:pfam05262 179 DKKVVEALREDNEKGVNFRRDMT---DLKERESQ----------EDAKRAQQLKEELDKkQIDADKAQQKAD-------- 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 888 hmdefkRTQKNLGNWKEEAQQLLQNGKSGREKSDqllsranlaKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKA 967
Cdd:pfam05262 238 ------FAQDNADKQRDEVRQKQQEAKNLPKPAD---------TSSPKEDKQVAENQKREIEKAQIEIKKNDEEALKAKD 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 968 EAEEAMKRLSYISQKvsDASDKTQQAERALGSAAADAQRAKNgAGEAlEISSEIEQEIGSLN--LEANVTADGALAMEKG 1045
Cdd:pfam05262 303 HKAFDLKQESKASEK--EAEDKELEAQKKREPVAEDLQKTKP-QVEA-QPTSLNEDAIDSSNpvYGLKVVDPITNLSELV 378
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157419140 1046 LASLKSEMREVEGELE--RKELEFDTNMDAVQMVITEA----QKVDTRAKNAGVTIQDTLN 1100
Cdd:pfam05262 379 LIDLKTEVRLRESAQQtiRRRGLYEREKDLVAIAITSGnaklQLVDIDLKNLEVIKESNFE 439
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
614-1093 |
4.63e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.66 E-value: 4.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 614 NQVKIQMDQFMQQLQRMEALISKAQggdgvvpDTELEGRMQQAEQALQDILRDAQIS----EGASRSLGLQLAKVRSQEN 689
Cdd:TIGR00618 362 EVATSIREISCQQHTLTQHIHTLQQ-------QKTTLTQKLQSLCKELDILQREQATidtrTSAFRDLQGQLAHAKKQQE 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 690 SYQSRLDDLKMTVE------------------RVRALGSQYQN------RVRDTHRLITQMQLSLAESEASL-GNTNIPA 744
Cdd:TIGR00618 435 LQQRYAELCAAAITctaqceklekihlqesaqSLKEREQQLQTkeqihlQETRKKAVVLARLLELQEEPCPLcGSCIHPN 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 745 SDHYV----GPN------GFKSLAQEATRLAESHVESASNMEQLTR-----ETEDYSKQALSLVRKALHEGVgSGSGSPD 809
Cdd:TIGR00618 515 PARQDidnpGPLtrrmqrGEQTYAQLETSEEDVYHQLTSERKQRASlkeqmQEIQQSFSILTQCDNRSKEDI-PNLQNIT 593
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 810 GAVVQGLVEKLEKTKSLAQQLTREATQAEIEA--------DRSYQHSLRL-LDSVSRLQGVSDQSFQVEEAKRIKQKADS 880
Cdd:TIGR00618 594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdlqdvrlhLQQCSQELALkLTALHALQLTLTQERVREHALSIRVLPKE 673
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 881 LSSLVTRHMDEFKRTQKNLGNWKEEAQQ---LLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLRE 957
Cdd:TIGR00618 674 LLASRQLALQKMQSEKEQLTYWKEMLAQcqtLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQAR 753
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 958 FDLQ-VDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALgsaAADAQRAKngagealEISSEIEQEIGSLNLEANVTA 1036
Cdd:TIGR00618 754 TVLKaRTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLR---EEDTHLLK-------TLEAEIGQEIPSDEDILNLQC 823
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 1037 DgalAMEKGLASLKSEMRE---VEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGV 1093
Cdd:TIGR00618 824 E---TLVQEEEQFLSRLEEksaTLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNG 880
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
573-604 |
8.57e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 41.14 E-value: 8.57e-05
10 20 30
....*....|....*....|....*....|...
gi 157419140 573 CNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCEH 604
Cdd:smart00180 1 CDCDPGGSASGTCDPDtGQCECKPNVTGRRCDR 33
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
813-1039 |
2.02e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 813 VQGLVEKLEKTKSLAQQLTRE--ATQAEIEAD--------RSYQHSLRLLDSVSRLqgVSDQSFQ--VEEAKRIKQKADS 880
Cdd:COG3883 53 YNELQAELEALQAEIDKLQAEiaEAEAEIEERreelgeraRALYRSGGSVSYLDVL--LGSESFSdfLDRLSALSKIADA 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 881 LSSLvtrhMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSmgnatfyEVESILKNLREFDL 960
Cdd:COG3883 131 DADL----LEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLA-------QLSAEEAAAEAQLA 199
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157419140 961 QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGA 1039
Cdd:COG3883 200 ELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAA 278
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
720-1000 |
2.09e-04 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 44.33 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 720 HRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALhe 799
Cdd:pfam06008 15 YKINYNLENLTKQLQEYLSPENAHKIQIEILEKELSSLAQETEELQKKATQTLAKAQQVNAESERTLGHAKELAEAIK-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 800 gvgsgsgspdgAVVQGLVEKLEKTKSLAQQL------TREATQAEIeadrsyQHSLRLLDSvsrlqgvSDQSFQVEEAKR 873
Cdd:pfam06008 93 -----------NLIDNIKEINEKVATLGENDfalpssDLSRMLAEA------QRMLGEIRS-------RDFGTQLQNAEA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 874 IKQKADSLsslvtrhmdeFKRTQKNLGNWKEEAQQLLQNGKSG-REKSDQL-----LSRANLAKSRAQEALSMGNAtfye 947
Cdd:pfam06008 149 ELKAAQDL----------LSRIQTWFQSPQEENKALANALRDSlAEYEAKLsdlreLLREAAAKTRDANRLNLANQ---- 214
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 157419140 948 vesilKNLREFdlqvdNRKAEAEEAMKRLsyISQKVSDASDKTQQAERALGSA 1000
Cdd:pfam06008 215 -----ANLREF-----QRKKEEVSEQKNQ--LEETLKTARDSLDAANLLLQEI 255
|
|
| growth_prot_Scy |
NF041483 |
polarized growth protein Scy; |
821-1091 |
2.30e-04 |
|
polarized growth protein Scy;
Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 45.59 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 821 EKTKSLAQQLTREATQAEIEADR---------------------SYQ-HSLRLLDSVSRLQGVSDQ--SFQVEEAKRIKQ 876
Cdd:NF041483 386 ATTRAAAEEAERIRREAEAEADRlrgeaadqaeqlkgaakddtkEYRaKTVELQEEARRLRGEAEQlrAEAVAEGERIRG 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 877 KAdslSSLVTRHMDEFKRTQKN-LGNWKEEAQQLLQNGKSGREK-SDQLLSRAN---------LAKSRAQ------EALS 939
Cdd:NF041483 466 EA---RREAVQQIEEAARTAEElLTKAKADADELRSTATAESERvRTEAIERATtlrrqaeetLERTRAEaerlraEAEE 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 940 MGNATFYEVESILKNLR-EFDLQVDNRKAEAEEAMKRLSyisqkvSDASDKTQQAERALGSAAADAQRAKNGAGEALE-- 1016
Cdd:NF041483 543 QAEEVRAAAERAARELReETERAIAARQAEAAEELTRLH------TEAEERLTAAEEALADARAEAERIRREAAEETErl 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 1017 ----------ISSEIEQEIGSLNLEANVTADGALAMEKGLA-SLKSemrEVEGELERKELEFDTNMDAVQM-VITEAQKV 1084
Cdd:NF041483 617 rteaaerirtLQAQAEQEAERLRTEAAADASAARAEGENVAvRLRS---EAAAEAERLKSEAQESADRVRAeAAAAAERV 693
|
....*..
gi 157419140 1085 DTRAKNA 1091
Cdd:NF041483 694 GTEAAEA 700
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
648-859 |
2.45e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.39 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDILRDAQISEGASRSLGL--QLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRD--THRLI 723
Cdd:COG3206 186 ELRKELEEAEAALEEFRQKNGLVDLSEEAKLLlqQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEllQSPVI 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 724 TQMQLSLAESEAslgntnipasdhyvgpngfkSLAQEATRLAESHVEsasnMEQLTRETEDYSKQALSLVRKALHEGVGS 803
Cdd:COG3206 266 QQLRAQLAELEA--------------------ELAELSARYTPNHPD----VIALRAQIAALRAQLQQEAQRILASLEAE 321
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 157419140 804 GSGSpdGAVVQGLVEKLEKTKSLAQQLTR-EATQAEIEadRSYQHSLRLLDS-VSRLQ 859
Cdd:COG3206 322 LEAL--QAREASLQAQLAQLEARLAELPElEAELRRLE--REVEVARELYESlLQRLE 375
|
|
| PspA |
COG1842 |
Phage shock protein A [Transcription, Signal transduction mechanisms]; |
904-1062 |
2.95e-04 |
|
Phage shock protein A [Transcription, Signal transduction mechanisms];
Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 43.28 E-value: 2.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 904 EEAQQLLQNGKSG------REKS-----DQLLSRANLAKSRAQEALSMGNatfyevESI----LKNLREFDLQVDNRKAE 968
Cdd:COG1842 33 RDMEEDLVEARQAlaqviaNQKRlerqlEELEAEAEKWEEKARLALEKGR------EDLareaLERKAELEAQAEALEAQ 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 969 AEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAK--------------NGAGEALEissEIEQEIgsLNLEANV 1034
Cdd:COG1842 107 LAQLEEQVEKLKEALRQLESKLEELKAKKDTLKARAKAAKaqekvnealsgidsDDATSALE---RMEEKI--EEMEARA 181
|
170 180 190
....*....|....*....|....*....|..
gi 157419140 1035 TADGALAMEKGL----ASLKSEMrEVEGELER 1062
Cdd:COG1842 182 EAAAELAAGDSLddelAELEADS-EVEDELAA 212
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
825-1057 |
3.02e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 825 SLAQQLTREATQAEIEADRsyQHSLRLLDSVSRLQgvSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKE 904
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQ--QEIAELEKELAALK--KEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 905 EAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFdlqVDNRKAEAEEAMKRLSYISQKVS 984
Cdd:COG4942 91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL---APARREQAEELRADLAELAALRA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157419140 985 DASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVE 1057
Cdd:COG4942 168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
913-1066 |
3.06e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 3.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 913 GKSGREKSDQLLSRANLAKSRAQEAlsmgnatfyEVESiLKNLREFdLQVDNRKAEaeeamKRLSYISQKVSDASDKTQQ 992
Cdd:TIGR02169 657 GGSRAPRGGILFSRSEPAELQRLRE---------RLEG-LKRELSS-LQSELRRIE-----NRLDELSQELSDASRKIGE 720
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157419140 993 AERALGSAAADAQRAKngagealEISSEIEQEIGSLnleanvtadgalamEKGLASLKSEMREVEGELERKELE 1066
Cdd:TIGR02169 721 IEKEIEQLEQEEEKLK-------ERLEELEEDLSSL--------------EQEIENVKSELKELEARIEELEED 773
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
648-1083 |
3.16e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 3.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 648 ELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ 727
Cdd:COG1196 327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 728 LSLAESEASLgntnipasdhyvgpngfKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVR--KALHEGVGSGS 805
Cdd:COG1196 407 EAEEALLERL-----------------ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEeeEALLELLAELL 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 806 GSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLV 885
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 886 TRHMDEFKRTQknlgnwkeEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDN- 964
Cdd:COG1196 550 NIVVEDDEVAA--------AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDt 621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 965 ---------RKAEAEEAMKRLSY------------------ISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEI 1017
Cdd:COG1196 622 llgrtlvaaRLEAALRRAVTLAGrlrevtlegeggsaggslTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157419140 1018 SSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQK 1083
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
646-1111 |
4.82e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.26 E-value: 4.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 646 DTELEGRMQQAEQALQDIlrDAQIS------EGASRSLGlQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQnRVRDT 719
Cdd:PRK02224 201 EKDLHERLNGLESELAEL--DEEIEryeeqrEQARETRD-EADEVLEEHEERREELETLEAEIEDLRETIAETE-REREE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 720 HRLITQMQLSLAESEASlgntnipASDHYVGPNGFKSLAQEA------------TRLAESHVESASNMEQLTRETEDYSK 787
Cdd:PRK02224 277 LAEEVRDLRERLEELEE-------ERDDLLAEAGLDDADAEAvearreeledrdEELRDRLEECRVAAQAHNEEAESLRE 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 788 QALSLVRKA--LHEGVGSgsgspDGAVVQGLVEKLEKTKSlaqqlTREATQAEIEADRSyqhslRLLDSVSRLQGVSDQS 865
Cdd:PRK02224 350 DADDLEERAeeLREEAAE-----LESELEEAREAVEDRRE-----EIEELEEEIEELRE-----RFGDAPVDLGNAEDFL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 866 FQVEEAK-RIKQKADSLSSlvtrhmdefkrTQKNLGNWKEEAQQLLQNGK------------------SGREKSDQLlsR 926
Cdd:PRK02224 415 EELREERdELREREAELEA-----------TLRTARERVEEAEALLEAGKcpecgqpvegsphvetieEDRERVEEL--E 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 927 ANLAKSRAQ--------EALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALG 998
Cdd:PRK02224 482 AELEDLEEEveeveerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 999 SAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAME---------KGLASLKSEMREVEGEL-ERK-ELEF 1067
Cdd:PRK02224 562 EAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDeierlrekrEALAELNDERRERLAEKrERKrELEA 641
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 157419140 1068 DTNMDAVQmvitEAQKVDTRAKNAGVTIQDTLNTL----DGLLHLMGM 1111
Cdd:PRK02224 642 EFDEARIE----EAREDKERAEEYLEQVEEKLDELreerDDLQAEIGA 685
|
|
| PspA |
COG1842 |
Phage shock protein A [Transcription, Signal transduction mechanisms]; |
816-1053 |
5.82e-04 |
|
Phage shock protein A [Transcription, Signal transduction mechanisms];
Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 42.50 E-value: 5.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 816 LVEKLEKTKSLAQQLTREATQAEIEADRsyqhslrlldSVSRLQGvsdqsfqveEAKRIKQKADSLsslvtrhmdefkrt 895
Cdd:COG1842 17 LLDKAEDPEKMLDQAIRDMEEDLVEARQ----------ALAQVIA---------NQKRLERQLEEL-------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 896 QKNLGNWKEEAQQLLQngkSGREKsdqlLSRANLAKSRAQEALSMGNATFYE-----VESILKNLREFDLQVDNRKAEAE 970
Cdd:COG1842 64 EAEAEKWEEKARLALE---KGRED----LAREALERKAELEAQAEALEAQLAqleeqVEKLKEALRQLESKLEELKAKKD 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 971 EAMKRlsyisQKVSDASDKTQQAERALGSAAA-----------DAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADga 1039
Cdd:COG1842 137 TLKAR-----AKAAKAQEKVNEALSGIDSDDAtsalermeekiEEMEARAEAAAELAAGDSLDDELAELEADSEVEDE-- 209
|
250
....*....|....
gi 157419140 1040 lamekgLASLKSEM 1053
Cdd:COG1842 210 ------LAALKAKM 217
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
652-1102 |
6.52e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.88 E-value: 6.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 652 RMQQAEQALQDILRDAQISEGASRSLGL---------QLAKVRSQENSyqsRLDDLKmtveRVRALGSQYQNRVRDTHRL 722
Cdd:TIGR00606 462 ELQQLEGSSDRILELDQELRKAERELSKaeknsltetLKKEVKSLQNE---KADLDR----KLRKLDQEMEQLNHHTTTR 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 723 iTQMqLSLAESEAS----LGNTNIPASDHYVGPNGF---------------KSLAQEATRLAESHVESAS---NMEQLTR 780
Cdd:TIGR00606 535 -TQM-EMLTKDKMDkdeqIRKIKSRHSDELTSLLGYfpnkkqledwlhsksKEINQTRDRLAKLNKELASleqNKNHINN 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 781 ETEDYSKQALSLVRKaLHEGVGSGSGSPDgavVQGLVEKLEKT-KSLA-------------QQLTREATQAEIEADRSYQ 846
Cdd:TIGR00606 613 ELESKEEQLSSYEDK-LFDVCGSQDEESD---LERLKEEIEKSsKQRAmlagatavysqfiTQLTDENQSCCPVCQRVFQ 688
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 847 HSLRLLDSVSRLQGVS----DQSFQVE-EAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQL---LQNGKSGRE 918
Cdd:TIGR00606 689 TEAELQEFISDLQSKLrlapDKLKSTEsELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVnrdIQRLKNDIE 768
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 919 KSDQLLSRANLAKSRAQEALSmgNATFyeVESILKNLREFDLQVDNRKAEAEEAMKRLSYisQKVSDASDKTQQAERALG 998
Cdd:TIGR00606 769 EQETLLGTIMPEEESAKVCLT--DVTI--MERFQMELKDVERKIAQQAAKLQGSDLDRTV--QQVNQEKQEKQHELDTVV 842
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 999 SAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVI 1078
Cdd:TIGR00606 843 SKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQ 922
|
490 500
....*....|....*....|....
gi 157419140 1079 TEAQKVDTRAKNAGVTIQDTLNTL 1102
Cdd:TIGR00606 923 QEKEELISSKETSNKKAQDKVNDI 946
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
619-1064 |
7.22e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.88 E-value: 7.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 619 QMDQFMQQLQRMEAlISKAQGGDGVVPDTELEGRMQQAEQALQdiLRDAQISEGAsrslglQLAKVRSQENSYQSRLDDL 698
Cdd:TIGR00606 180 SATRYIKALETLRQ-VRQTQGQKVQEHQMELKYLKQYKEKACE--IRDQITSKEA------QLESSREIVKSYENELDPL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 699 KmtvERVRALgsqyQNRVRDTHRLITQMQlSLAESEASLGNTNIPASDHYVGPngFKSLAQEATRLAESHVESASNMEQ- 777
Cdd:TIGR00606 251 K---NRLKEI----EHNLSKIMKLDNEIK-ALKSRKKQMEKDNSELELKMEKV--FQGTDEQLNDLYHNHQRTVREKERe 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 778 ---LTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQglvEKLEKTKSLAQQLtreATQAEIEADRSYQHSLRLLDS 854
Cdd:TIGR00606 321 lvdCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQ---EHIRARDSLIQSL---ATRLELDGFERGPFSERQIKN 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 855 VSRLQgvsdQSFQVEEAKRIKQKADSLSS---LVTRHMDEFKRTQKNLGNWKE--------EAQQL------LQNGKSGr 917
Cdd:TIGR00606 395 FHTLV----IERQEDEAKTAAQLCADLQSkerLKQEQADEIRDEKKGLGRTIElkkeilekKQEELkfvikeLQQLEGS- 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 918 ekSDQLLSRAN-LAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMkrlsyiSQKVSDASDKTQQAERA 996
Cdd:TIGR00606 470 --SDRILELDQeLRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEM------EQLNHHTTTRTQMEMLT 541
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 997 LGSAAADAQRAKNGAGEALEISS---------EIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKE 1064
Cdd:TIGR00606 542 KDKMDKDEQIRKIKSRHSDELTSllgyfpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKE 618
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
816-1028 |
7.84e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 7.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 816 LVEKLEKTKSLAQ--QLTREATQAEIEADRsyqhsLRLLDSVSRLQgvsdqsFQVEEAKRIKQKADSLSSLVTRHMDEFK 893
Cdd:COG4913 244 LEDAREQIELLEPirELAERYAAARERLAE-----LEYLRAALRLW------FAQRRLELLEAELEELRAELARLEAELE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 894 RTQKNLGNWKEEA----QQLLQNGksGREKSD--QLLSRANLAKSRAQEALsmgnatfyevESILKNLREFDLQVDNRKA 967
Cdd:COG4913 313 RLEARLDALREELdeleAQIRGNG--GDRLEQleREIERLERELEERERRR----------ARLEALLAALGLPLPASAE 380
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157419140 968 EAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNgagealeissEIEQEIGSL 1028
Cdd:COG4913 381 EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR----------ELEAEIASL 431
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
757-1068 |
1.14e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 757 LAQEATRL--AESHVESASNMEQLTRETEDYSKQALSLVRKALHEgvgsgsgspdgAVV---QGLVEKLEktkSLAQQLT 831
Cdd:COG3096 838 LAALRQRRseLERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQ-----------ANLladETLADRLE---ELREELD 903
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 832 rEATQAEIEADRSYQHSLRLLDSVSRLQgvSD-QSF-----QVEEAK----RIKQKADSLSSLVTR--HMdefkrtqknl 899
Cdd:COG3096 904 -AAQEAQAFIQQHGKALAQLEPLVAVLQ--SDpEQFeqlqaDYLQAKeqqrRLKQQIFALSEVVQRrpHF---------- 970
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 900 gNWKEEAQQLLQNgksgREKSDQL---LSRANLAKSRAQEALSMGNATFYEVESILKNLREfdlQVDNRKAEAEEAMKRL 976
Cdd:COG3096 971 -SYEDAVGLLGEN----SDLNEKLrarLEQAEEARREAREQLRQAQAQYSQYNQVLASLKS---SRDAKQQTLQELEQEL 1042
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 977 SYISQKVSDASDKTQQAERalgsaaadaqrakngagealeisSEIEQEIGSLNLEANvtadgalAMEKGLASLKSEMREV 1056
Cdd:COG3096 1043 EELGVQADAEAEERARIRR-----------------------DELHEELSQNRSRRS-------QLEKQLTRCEAEMDSL 1092
|
330
....*....|..
gi 157419140 1057 EGELerKELEFD 1068
Cdd:COG3096 1093 QKRL--RKAERD 1102
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
818-1066 |
1.25e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 42.21 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 818 EKLEKTKSLAQQLtreatqAEIEADRSyqhslRLLDSVSRLQGVSDQSFqvEEAKRIKQKADSLSSLvtrhMDEFKRTQK 897
Cdd:COG1340 47 ELNAQVKELREEA------QELREKRD-----ELNEKVKELKEERDELN--EKLNELREELDELRKE----LAELNKAGG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 898 NLGNWKEEAQQL---LQNGKSGREKSDQLLSRANLAKSRAQEAlsmgnatfyevesilKNLREFDLQVDNRKAEAEEAMK 974
Cdd:COG1340 110 SIDKLRKEIERLewrQQTEVLSPEEEKELVEKIKELEKELEKA---------------KKALEKNEKLKELRAELKELRK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 975 RLSYISQKVSDASDKTQQAERALGSA--AADAQRAkngagEALEISSEIE---QEIGSLNLEANVTADGALAMEKGLASL 1049
Cdd:COG1340 175 EAEEIHKKIKELAEEAQELHEEMIELykEADELRK-----EADELHKEIVeaqEKADELHEEIIELQKELRELRKELKKL 249
|
250
....*....|....*..
gi 157419140 1050 KSEMREVEGELERKELE 1066
Cdd:COG1340 250 RKKQRALKREKEKEELE 266
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
755-1057 |
1.59e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.63 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 755 KSLAQEATRlaesHVESASNMEQLT-RE---TEDYskQA----LSLVRKAL--HEGVGSGSgspdgAVVQGLVEKLEK-- 822
Cdd:COG3096 299 RQLAEEQYR----LVEMARELEELSaREsdlEQDY--QAasdhLNLVQTALrqQEKIERYQ-----EDLEELTERLEEqe 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 823 --TKSLAQQLTR---EATQAEIEADR------SYQhslRLLDSVSRLQGVSDQSFQ-VEEAKRIKQKADslsslvtrhmd 890
Cdd:COG3096 368 evVEEAAEQLAEaeaRLEAAEEEVDSlksqlaDYQ---QALDVQQTRAIQYQQAVQaLEKARALCGLPD----------- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 891 efkRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVE---------SILKNLREFDLQ 961
Cdd:COG3096 434 ---LTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVErsqawqtarELLRRYRSQQAL 510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 962 VDnrkaeaeeamkRLSYISQKVSDASDKTQQAERALGSAAADAQRAK---NGAGEALEISSEIEQEIGSLNLEANVTADG 1038
Cdd:COG3096 511 AQ-----------RLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGqqlDAAEELEELLAELEAQLEELEEQAAEAVEQ 579
|
330
....*....|....*....
gi 157419140 1039 ALAMEKGLASLKSEMREVE 1057
Cdd:COG3096 580 RSELRQQLEQLRARIKELA 598
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
980-1076 |
2.13e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 980 SQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGE 1059
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90
....*....|....*..
gi 157419140 1060 LERKELEFDTNMDAVQM 1076
Cdd:COG4942 99 LEAQKEELAELLRALYR 115
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
921-1106 |
3.04e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 3.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 921 DQLLSRANLAKSRAQEALSmgnatfyEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSA 1000
Cdd:COG1196 235 RELEAELEELEAELEELEA-------ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 1001 AADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
Cdd:COG1196 308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387
|
170 180
....*....|....*....|....*.
gi 157419140 1081 AQKVDTRAKNAGVTIQDTLNTLDGLL 1106
Cdd:COG1196 388 LLEALRAAAELAAQLEELEEAEEALL 413
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
947-1068 |
3.30e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.04 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 947 EVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKngagEALEissEIEQEIG 1026
Cdd:COG4372 53 ELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQ----EELE---ELQKERQ 125
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 157419140 1027 SLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFD 1068
Cdd:COG4372 126 DLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELA 167
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
870-1091 |
3.37e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 870 EAKRIKQKADSLSSlvtrHMDEFKRTQKNLGNWKEEAQQLLQNgksgREKSDQLlsRANLAKSRAQEALSMGnATFYEVE 949
Cdd:COG4913 219 EEPDTFEAADALVE----HFDDLERAHEALEDAREQIELLEPI----RELAERY--AAARERLAELEYLRAA-LRLWFAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 950 silknlREFDLqVDNRKAEAEEAMKRLSyisQKVSDASDKTQQAERALgsAAADAQRAKNGaGEALEissEIEQEIGSLN 1029
Cdd:COG4913 288 ------RRLEL-LEAELEELRAELARLE---AELERLEARLDALREEL--DELEAQIRGNG-GDRLE---QLEREIERLE 351
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157419140 1030 LEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNA 1091
Cdd:COG4913 352 RELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
484-509 |
3.56e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 36.56 E-value: 3.56e-03
10 20
....*....|....*....|....*.
gi 157419140 484 CPPGVTGARCELCADGYFGDPFGEHG 509
Cdd:pfam00053 22 CKPGVTGRHCDRCKPGYYGLPSDPPQ 47
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
663-1033 |
3.66e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 41.16 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 663 ILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNI 742
Cdd:COG0840 2 LILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 743 PASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEK 822
Cdd:COG0840 82 LALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 823 TKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSS------LVTRHMDEFKRTQ 896
Cdd:COG0840 162 ALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEgdltvrIDVDSKDEIGQLA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 897 KNLGNWKEEAQQLLQNGKSG----REKSDQLLSRANLAKSRAQEALSmgnatfyEVESILknlrefdlqvdnrkAEAEEA 972
Cdd:COG0840 242 DAFNRMIENLRELVGQVRESaeqvASASEELAASAEELAAGAEEQAA-------SLEETA--------------AAMEEL 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157419140 973 MKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEAN 1033
Cdd:COG0840 301 SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQ 361
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
891-1109 |
3.97e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 40.12 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 891 EFKRTQKNLGNWKEEAQQLLQNGKSGREKSdqllsranlaksraqealsmgnatfyEVESILKNLREFDLQVDNRK---- 966
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLE--------------------------SVEALLKKHEALEAELAAHEerve 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 967 ---AEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLN-LEANVTADGALAM 1042
Cdd:cd00176 58 alnELGEQLIEEGHPDAEEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEeKEAALASEDLGKD 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 1043 EKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAgvTIQDTLNTLDGLLHLM 1109
Cdd:cd00176 138 LESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEE--KLEELNERWEELLELA 202
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
757-1093 |
4.01e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 4.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 757 LAQEATRL--AESHVESASNMEQLTRETEDYSKQALSLVRKALhegvgsgsgsPDGAV--VQGLVEKLEKtksLAQQLTR 832
Cdd:PRK04863 839 LRQLNRRRveLERALADHESQEQQQRSQLEQAKEGLSALNRLL----------PRLNLlaDETLADRVEE---IREQLDE 905
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 833 eATQAEIEADRsYQHSLRLLDS-VSRLQgvSDQS------FQVEEAK----RIKQKADSLSSLVTRhmdefkrtqKNLGN 901
Cdd:PRK04863 906 -AEEAKRFVQQ-HGNALAQLEPiVSVLQ--SDPEqfeqlkQDYQQAQqtqrDAKQQAFALTEVVQR---------RAHFS 972
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 902 WkEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLR-EFDLQVDNRKaEAEEAMKRLSYis 980
Cdd:PRK04863 973 Y-EDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKsSYDAKRQMLQ-ELKQELQDLGV-- 1048
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 981 qkvsdasdktqqaeralgsaaadaqRAKNGAGEALEI-SSEIEQeigslNLEANVTADGALamEKGLASLKSEMREVEGE 1059
Cdd:PRK04863 1049 -------------------------PADSGAEERARArRDELHA-----RLSANRSRRNQL--EKQLTFCEAEMDNLTKK 1096
|
330 340 350
....*....|....*....|....*....|....
gi 157419140 1060 LERKELEFDTNMDAVQMVITEAQKVDTRAKNAGV 1093
Cdd:PRK04863 1097 LRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGV 1130
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
947-1083 |
4.75e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 4.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157419140 947 EVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL---EISSeIEQ 1023
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnkEYEA-LQK 96
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157419140 1024 EIGSLNLEANVTADGAL-------AMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQK 1083
Cdd:COG1579 97 EIESLKRRISDLEDEILelmerieELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
28-78 |
7.56e-03 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 35.79 E-value: 7.56e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 157419140 28 CDCNG---KSRQCifdrelHRQTGngfRCLnCNDNTDGIHCEKCKNGFYRHRER 78
Cdd:cd00055 2 CDCNGhgsLSGQC------DPGTG---QCE-CKPNTTGRRCDRCAPGYYGLPSQ 45
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
28-86 |
8.47e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 35.41 E-value: 8.47e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157419140 28 CDCNG---KSRQCifdrelHRQTGngfRCLnCNDNTDGIHCEKCKNGFYRHRerdRCLPCNC 86
Cdd:pfam00053 1 CDCNPhgsLSDTC------DPETG---QCL-CKPGVTGRHCDRCKPGYYGLP---SDPPQGC 49
|
|
| |
