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Conserved domains on  [gi|157384908|ref|YP_001481136|]
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NADH dehydrogenase subunit 3 (mitochondrion) [Phallusia mammillata]

Protein Classification

NADH dehydrogenase subunit 3( domain architecture ID 10009625)

NADH dehydrogenase subunit 3 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 1-124 7.24e-27

NADH dehydrogenase subunit 3; Provisional


:

Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 95.73  E-value: 7.24e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908   1 MLFTLYFFSVCLIVGALGYLGssstkglyGHYKRLVISGGDKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILI 80
Cdd:MTH00203   1 MNLIMLFFLIALLLSLILLFI--------AFWLPKVNPDGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIAL 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 157384908  81 IIPMVVTGAEGYEALsawgLGKSFFLVVVSMAAYYEVMGGVVSF 124
Cdd:MTH00203  73 LLPLPWSNQLSSLSL----LLAFLFLILLTLGLIYEWLQGGLEW 112
 
Name Accession Description Interval E-value
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 1-124 7.24e-27

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 95.73  E-value: 7.24e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908   1 MLFTLYFFSVCLIVGALGYLGssstkglyGHYKRLVISGGDKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILI 80
Cdd:MTH00203   1 MNLIMLFFLIALLLSLILLFI--------AFWLPKVNPDGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIAL 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 157384908  81 IIPMVVTGAEGYEALsawgLGKSFFLVVVSMAAYYEVMGGVVSF 124
Cdd:MTH00203  73 LLPLPWSNQLSSLSL----LLAFLFLILLTLGLIYEWLQGGLEW 112
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
42-116 8.05e-08

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 46.65  E-value: 8.05e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157384908   42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTgaegYEALSAWGLGKSF-FLVVVSMAAYYE 116
Cdd:pfam00507  16 KLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVEVVFLFPWAVS----FRELGWFGFVEMLiFIAILLVGLVYA 87
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 42-115 8.06e-05

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 38.95  E-value: 8.06e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157384908  42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTgaegYEALSAWGLGKSFFLVVVSMAAYY 115
Cdd:COG0838   38 KLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVEVVFLFPWAVV----FRELGWFGLIEMLVFIAILLVGLI 107
 
Name Accession Description Interval E-value
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 1-124 7.24e-27

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 95.73  E-value: 7.24e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908   1 MLFTLYFFSVCLIVGALGYLGssstkglyGHYKRLVISGGDKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILI 80
Cdd:MTH00203   1 MNLIMLFFLIALLLSLILLFI--------AFWLPKVNPDGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIAL 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 157384908  81 IIPMVVTGAEGYEALsawgLGKSFFLVVVSMAAYYEVMGGVVSF 124
Cdd:MTH00203  73 LLPLPWSNQLSSLSL----LLAFLFLILLTLGLIYEWLQGGLEW 112
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
42-116 8.05e-08

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 46.65  E-value: 8.05e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157384908   42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTgaegYEALSAWGLGKSF-FLVVVSMAAYYE 116
Cdd:pfam00507  16 KLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVEVVFLFPWAVS----FRELGWFGFVEMLiFIAILLVGLVYA 87
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 41-84 1.40e-07

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 46.47  E-value: 1.40e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPM 84
Cdd:MTH00106  32 EKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPL 75
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 42-116 1.90e-07

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 45.92  E-value: 1.90e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384908  42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTgaEGYEALSAWGLGKSFFLVVVSMAAYYE 116
Cdd:MTH00161  33 KSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFI--FKTSNMMSWLITSSFFILILLLGLYYE 105
ND3 MTH00148
NADH dehydrogenase subunit 3; Provisional
 1-120 3.80e-07

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214433 [Multi-domain]  Cd Length: 117  Bit Score: 45.23  E-value: 3.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908   1 MLFTLYFFSVCLIVG-ALGYLGSSSTKglyghykrLVISGGDKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEIL 79
Cdd:MTH00148   1 MLSILLSLLFALILSpVLLLLGLVLSK--------RSYSDREKSSPFECGFDPISSARSPFSLRFFLLAILFLVFDVEIV 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 157384908  80 IIIPMVVTGAEGYealSAWGLGKSF-FLVVVSMAAYYEVMGG 120
Cdd:MTH00148  73 LLFPVLQSLGSSF---SVWSLTSLFiFLLILILGLFHEWNEG 111
ND3 MTH00042
NADH dehydrogenase subunit 3; Validated
 1-84 4.75e-07

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 177117 [Multi-domain]  Cd Length: 116  Bit Score: 44.97  E-value: 4.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908   1 MLFTLYFFSVCLIVgalgylgsSSTKGLYGHYKRLVISGGDKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILI 80
Cdd:MTH00042   1 MTNLIFFLLIILIL--------TSLLLLAGHFLPSRSPDLEKSSPYECGFDPLNSARLPFSFRFFLVAILFLLFDLEIAL 72


                 ....
gi 157384908  81 IIPM 84
Cdd:MTH00042  73 LFPL 76
ND3 MTH00069
NADH dehydrogenase subunit 3; Provisional
 41-83 6.86e-06

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177141 [Multi-domain]  Cd Length: 114  Bit Score: 41.90  E-value: 6.86e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIP 83
Cdd:MTH00069  31 EKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLP 73
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 42-115 8.06e-05

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 38.95  E-value: 8.06e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157384908  42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTgaegYEALSAWGLGKSFFLVVVSMAAYY 115
Cdd:COG0838   38 KLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVEVVFLFPWAVV----FRELGWFGLIEMLVFIAILLVGLI 107
ND3 MTH00136
NADH dehydrogenase subunit 3; Provisional
 42-84 8.51e-05

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177194 [Multi-domain]  Cd Length: 116  Bit Score: 39.13  E-value: 8.51e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 157384908  42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPM 84
Cdd:MTH00136  34 KLSPYECGFDPLGSARLPFSLRFFLVAILFLLFDLEIALLLPL 76
ND3 MTH00018
NADH dehydrogenase subunit 3; Validated
 41-121 9.74e-05

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164592 [Multi-domain]  Cd Length: 113  Bit Score: 38.89  E-value: 9.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTgaegYEALSAWGLGKSF-FLVVVSMAAYYE-VM 118
Cdd:MTH00018  32 EKVSAYECGFDPFGFPGRPFSIRFFLIGILFLIFDLEISFLFPWCVL----YNQIAPFGFWTMVgFLFILTLGLIYEwIK 107


                 ...
gi 157384908 119 GGV 121
Cdd:MTH00018 108 GGL 110
ND3 MTH00113
NADH dehydrogenase subunit 3; Provisional
 41-84 1.11e-04

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177175 [Multi-domain]  Cd Length: 114  Bit Score: 38.71  E-value: 1.11e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPM 84
Cdd:MTH00113  32 EKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPL 75
ND3 MTH00012
NADH dehydrogenase subunit 3; Validated
 41-116 2.67e-04

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164588 [Multi-domain]  Cd Length: 117  Bit Score: 37.92  E-value: 2.67e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTGAEGYEALSAwgLGKSFFLVVVSMAAYYE 116
Cdd:MTH00012  34 EKTSPFECGFDPHKTARIPFSLRFFLLAIIFIVFDIEIVLLMPVPTILMTSTSKTVV--YTSILFLLILVIGLIHE 107
ND3 MTH00030
NADH dehydrogenase subunit 3; Provisional
 41-120 3.75e-04

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 164603 [Multi-domain]  Cd Length: 123  Bit Score: 37.60  E-value: 3.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTGAEgYEALSAWGLGKsfFLVVVSMAAYYEVMGG 120
Cdd:MTH00030  42 EKSSIYECGFDPFGKIRTPFTIKFVLVGILFMIFDIEISFLFPWSIVFNQ-LNLFSFWIVYT--FLIVLAIGLAYEWIKG 118
ND3 MTH00055
NADH dehydrogenase subunit 3; Provisional
 41-87 1.01e-03

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177128 [Multi-domain]  Cd Length: 118  Bit Score: 36.23  E-value: 1.01e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 157384908  41 DKGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVT 87
Cdd:MTH00055  37 EKVSVYECGFDPFESSRIPFSVRFFLVGILFLIFDLEISFLFPWCVV 83
ND3 MTH00202
NADH dehydrogenase subunit 3; Provisional
 42-116 3.32e-03

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214455 [Multi-domain]  Cd Length: 117  Bit Score: 34.97  E-value: 3.32e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157384908  42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVTGAEGYealSAWG-LGKSFFLVVVSMAAYYE 116
Cdd:MTH00202  35 KSSPFECGFDPKESARLPFSMRFFLLAVIFLVFDIEIALLLPLPLVLKSSW---SKGGlLGGTIFLLILIGGLIHE 107
PRK08489 PRK08489
NAD(P)H-quinone oxidoreductase subunit 3;
42-109 5.57e-03

NAD(P)H-quinone oxidoreductase subunit 3;


Pssm-ID: 181448 [Multi-domain]  Cd Length: 129  Bit Score: 34.26  E-value: 5.57e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157384908  42 KGSSYECGFVdMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVVtgaeGYEALSAWGLGKSFFLVVV 109
Cdd:PRK08489  47 KLAIYECGPE-PVKQPNRISSHFYIMALLFILFDVEIVFMFPWAV----DFKLLGLFGLIEMLLFIVL 109
ND3 MTH00092
NADH dehydrogenase subunit 3; Provisional
 42-86 7.43e-03

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177155  Cd Length: 111  Bit Score: 33.71  E-value: 7.43e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 157384908  42 KGSSYECGFVDMNESMNTYTMQFYIIGLSFMLFDLEILIIIPMVV 86
Cdd:MTH00092  34 KVSSFECGFESVGKIQNSFSIHFFKIMLMFVIFDLEIVMFLGLLV 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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