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Conserved domains on  [gi|1570863970|gb|RYT67443|]
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PH domain-containing protein [Blautia obeum]

Protein Classification

PH domain-containing protein( domain architecture ID 10508669)

bacterial Pleckstrin homology (bPH) domain-containing protein may be involved in protein-protein interactions

CATH:  2.30.29.50
Gene Ontology:  GO:0005515
PubMed:  15493994|22728242|19913036
SCOP:  3000134

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
bPH_2 pfam03703
Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies ...
 16-93 3.08e-21

Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.


:

Pssm-ID: 427450 [Multi-domain]  Cd Length: 78  Bit Score: 80.72  E-value: 3.08e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570863970  16 WTFTTYTVTDEFISIDSGLLNKVENDCYMYKVIDVRLETTLMERILGIGTIHCFTGDVTDPDLKLQHIKNAKEIKDFI 93
Cdd:pfam03703   1 YRATGYTITDRRVVVRSGILGRKRVDIPLERIQDVSLSQSPLQRRLGLGTIVIDTAGGSGVRLPLRDVPDAEELREWL 78
 
Name Accession Description Interval E-value
bPH_2 pfam03703
Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies ...
 16-93 3.08e-21

Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.


Pssm-ID: 427450 [Multi-domain]  Cd Length: 78  Bit Score: 80.72  E-value: 3.08e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570863970  16 WTFTTYTVTDEFISIDSGLLNKVENDCYMYKVIDVRLETTLMERILGIGTIHCFTGDVTDPDLKLQHIKNAKEIKDFI 93
Cdd:pfam03703   1 YRATGYTITDRRVVVRSGILGRKRVDIPLERIQDVSLSQSPLQRRLGLGTIVIDTAGGSGVRLPLRDVPDAEELREWL 78
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 14-101 2.26e-13

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 65.11  E-value: 2.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570863970  14 LPWTFTTYTVTDEFISIDSGLLNKVENDCYMYKVIDVRLETTLMERILGIGTIHCFT--GDVTDPDLKLQHIKNAKEIKD 91
Cdd:COG3428    61 LRWRTTRYRITDDRLIVRSGVLSRKRREIPLDRIQSVDVSQPLLHRLFGLGTVRIETagGGESEVELDALSVPEAERLRR 140

                          90
                  ....*....|
gi 1570863970  92 FILKQSEQER 101
Cdd:COG3428   141 LLLERAAGAA 150
PRK12999 PRK12999
pyruvate carboxylase; Reviewed
 21-91 7.00e-04

pyruvate carboxylase; Reviewed


Pssm-ID: 237263 [Multi-domain]  Cd Length: 1146  Bit Score: 38.20  E-value: 7.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570863970   21 YT-----VTDEFI--SIDSGL--------LNKVENdcyMYKVIDVRLETT-LMErilgiGTIhCFTGDVTDPDLK---LQ 81
Cdd:PRK12999   621 YTnypdnVVRAFVreAAAAGIdvfrifdsLNWVEN---MRVAIDAVRETGkIAE-----AAI-CYTGDILDPARAkydLD 691

                           90
                   ....*....|.
gi 1570863970   82 HIKN-AKEIKD 91
Cdd:PRK12999   692 YYVDlAKELEK 702
 
Name Accession Description Interval E-value
bPH_2 pfam03703
Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies ...
 16-93 3.08e-21

Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.


Pssm-ID: 427450 [Multi-domain]  Cd Length: 78  Bit Score: 80.72  E-value: 3.08e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1570863970  16 WTFTTYTVTDEFISIDSGLLNKVENDCYMYKVIDVRLETTLMERILGIGTIHCFTGDVTDPDLKLQHIKNAKEIKDFI 93
Cdd:pfam03703   1 YRATGYTITDRRVVVRSGILGRKRVDIPLERIQDVSLSQSPLQRRLGLGTIVIDTAGGSGVRLPLRDVPDAEELREWL 78
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 14-101 2.26e-13

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 65.11  E-value: 2.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570863970  14 LPWTFTTYTVTDEFISIDSGLLNKVENDCYMYKVIDVRLETTLMERILGIGTIHCFT--GDVTDPDLKLQHIKNAKEIKD 91
Cdd:COG3428    61 LRWRTTRYRITDDRLIVRSGVLSRKRREIPLDRIQSVDVSQPLLHRLFGLGTVRIETagGGESEVELDALSVPEAERLRR 140

                          90
                  ....*....|
gi 1570863970  92 FILKQSEQER 101
Cdd:COG3428   141 LLLERAAGAA 150
PRK12999 PRK12999
pyruvate carboxylase; Reviewed
 21-91 7.00e-04

pyruvate carboxylase; Reviewed


Pssm-ID: 237263 [Multi-domain]  Cd Length: 1146  Bit Score: 38.20  E-value: 7.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570863970   21 YT-----VTDEFI--SIDSGL--------LNKVENdcyMYKVIDVRLETT-LMErilgiGTIhCFTGDVTDPDLK---LQ 81
Cdd:PRK12999   621 YTnypdnVVRAFVreAAAAGIdvfrifdsLNWVEN---MRVAIDAVRETGkIAE-----AAI-CYTGDILDPARAkydLD 691

                           90
                   ....*....|.
gi 1570863970   82 HIKN-AKEIKD 91
Cdd:PRK12999   692 YYVDlAKELEK 702
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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