|
Name |
Accession |
Description |
Interval |
E-value |
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
57-887 |
0e+00 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 917.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVEKWWHQRIKEQAS-KISEaDKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPA 135
Cdd:COG0495 8 KEIEKKWQKYWEENGTfKADE-DSSKPKYYVLDMFPYPSGRLHMGHVRNYTIGDVVARYKRMQGYNVLHPMGWDAFGLPA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 136 ENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVL 215
Cdd:COG0495 87 ENAAIKNGVHPAEWTYENIANMRRQLKRLGLSYDWSREIATCDPEYYKWTQWIFLQLYEKGLAYRKEAPVNWCPVDQTVL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 216 ANEQVDEhGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEW-YGIKGMQAHWIGDCVGCHLDFTLKvhgqATGE 294
Cdd:COG0495 167 ANEQVID-GRCWRCGAPVEKKELPQWFLKITDYADELLDDLDKLDGWpEKVKTMQRNWIGRSEGAEVDFPVE----GSDE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 295 KLTAYTATPEAIYGTSHVAISPSHRLLH--GHSSLKEAL--------------RMALVPGKD-CLTPVMAVNMLTQQEVP 357
Cdd:COG0495 242 KITVFTTRPDTLFGATFMVLAPEHPLVKelATPEQNAAVaafieeakkkseieRTSETKEKTgVFTGLYAINPLTGEKIP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 358 V-------------VILA-------------KADLEgsldskIgIPSTSSEDTILAQTLGLAYSEvietlpDGTerLSSS 411
Cdd:COG0495 322 IwiadyvlmdygtgAVMAvpahdqrdfefakKYGLP------I-KQVIAPEDGDDPDILEEAYTG------DGV--LINS 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 412 AEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKG 491
Cdd:COG0495 387 GEFDGLDSEEAKEAIIEWLEEKGLGKRKVNYRLRDWLISRQRYWGEPIPIIHCEDCGVVPVPEDQLPVELPEDVDFDPTG 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 492 GPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYA 571
Cdd:COG0495 467 GSPLARAPEWVNVTCPKCGGPARRETDTMDTFVDSSWYYLRYTDPHNDEAPFDPEAANYWLPVDQYIGGIEHAILHLLYA 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 572 RFFSHFCHDQKMVKHREPFHKLLAQGLIkgqtfrlpsgqylqrEEVDLTGSVpvhaktkeklEVTWEKMSKSKHNGVDPE 651
Cdd:COG0495 547 RFFTKVLRDLGLVSFDEPFKRLLTQGMV---------------LEVGKDGVV----------IGGIEKMSKSKGNVVDPD 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 652 EVVEQYGIDTIRLYILFAAPPEKDILWDvkTDALPGVLRWQQRLWtlttRFIEARASGKSPQPQLLSNKEKAEARKLwey 731
Cdd:COG0495 602 EIIEKYGADTLRLFEMFAGPPERDLEWS--DSGVEGAYRFLNRVW----RLVVDEAEALKLDVADLSEADKELRRAL--- 672
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 732 kNSVISQVTTHFtEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLalvprklc 811
Cdd:COG0495 673 -HKTIKKVTEDI-ERLRFNTAIAALMELVNALYKAKDSGEADRAVLREALETLVLLLAPFAPHIAEELWERL-------- 742
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1565200264 812 AHytwDASVLLQAWPAVDPEFLQQpEVVQMAVLINNKACGKIPVPQQVarDQDKVHEFVLQSELGVRLLQGRSIKK 887
Cdd:COG0495 743 GH---EGSVADAPWPEADEAALVE-DEVTIVVQVNGKVRGKIEVPADA--SKEELEAAALADEKVQKFLEGKTIRK 812
|
|
| leuS_bact |
TIGR00396 |
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases ... |
59-901 |
0e+00 |
|
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both eubacterial and mitochondrial leucyl-tRNA synthetases. It generates higher scores for some valyl-tRNA synthetases than for any archaeal or eukaryotic cytosolic leucyl-tRNA synthetase. Note that the enzyme from Aquifex aeolicus is split into alpha and beta chains; neither chain is long enough to score above the trusted cutoff, but the alpha chain scores well above the noise cutoff. The beta chain must be found by a model and search designed for partial length matches. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273057 [Multi-domain] Cd Length: 842 Bit Score: 846.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 59 VEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENA 138
Cdd:TIGR00396 6 IEEKWQQKWDENKTFKVTDDSSKPKYYILSMFPYPSGALHMGHVRNYTITDVLSRYYRMKGYNVLHPIGWDAFGLPAENA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 139 AVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANE 218
Cdd:TIGR00396 86 AIKRGIHPAKWTYENIANMKKQLQALGFSYDWDREIATCDPEYYKWTQWIFLELFEKGLAYVKEADVNWCPNDGTVLANE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 219 QVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWY-GIKGMQAHWIGDCVGCHLDFTLKVHgqatGEKLT 297
Cdd:TIGR00396 166 QVDSDGRSWRGDTPVEKKELKQWFLKITAYAEELLNDLEELDHWPeSVKEMQRNWIGKSEGVEITFKIADH----DEKIT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 298 AYTATPEAIYGTSHVAISPSHRL--------------LHGHSSLKEALRMALVPGKD-CLTPVMAVNMLTQQEVPVVILA 362
Cdd:TIGR00396 242 VFTTRPDTIFGVTYLALAPEHPLvekaaennpkvaafIKKILNKTVAERTKATKEKKgVDTGIKAIHPLTGEKIPIWVAN 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 363 KADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPD---------GTERLSSSAEFTGMTRQDAFLALTQKARGK 433
Cdd:TIGR00396 322 YVLMEYGTGAVMGVPAHDERDFEFAQKYGLPIKPVIDPAEKdlsltaaytEDGVLVNSGEFNGLNSSEARNAIIDMLEKE 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 434 RVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAA 513
Cdd:TIGR00396 402 GKGKRKVNYRLRDWGFSRQRYWGEPIPIIHCEDGGVVPVPEEDLPVILPEDVVYDGDGGSPLSRIPEWVNVTCPSCGKPA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 514 KRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKL 593
Cdd:TIGR00396 482 LRETDTMDTFAGSSWYYLRYLDPKNTDGPFDKEKAEYWLPVDLYIGGIEHAILHLLYARFFHKFLRDIGYVNTKEPFKKL 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 594 LAQGLIKGQTFRlPSGQyLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPE 673
Cdd:TIGR00396 562 INQGMVLGFYYP-PNGK-VPADVLTERDEKGKDKAGGELVYVGYEKMSKSKGNGIDPQEIVESYGADALRLFIMFMGPIA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 674 KDILWDvkTDALPGVLRWQQRLWTLTTRfIEARASGKSPQPQLLSNKEKAEARKLweykNSVISQVTTHFTEDFSLNSAI 753
Cdd:TIGR00396 640 ASLEWN--ESGLEGARRFLDRVWNLVYE-ITGELDAASLTVTALEEAQKELRRDV----HKFLKKVTEDLEKRESFNTAI 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 754 SQLMGLSNALSQASQSVILhspefEDALCALMVMAAPLAPHVTSEIWAGLALVPrklcahYTWDAsvllQAWPAVDPEFL 833
Cdd:TIGR00396 713 SAMMELLNKLYKAKKEALM-----LEYLKGFVTVLSPFAPHLAEELWEKLGSEP------FIIDN----AKWPVVDETAL 777
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1565200264 834 QQPEvVQMAVLINNKACGKIPVPQQVarDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPrTALINFLV 901
Cdd:TIGR00396 778 VEDK-TLIVVQVNGKFRAKITVPKDA--DEEQVEELAKQDPEVKKYLENKTIKKVIYVP-GKLVNFVI 841
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
76-892 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 596.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 76 EADKSKPKFYVLSMFPYPSGK-LHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNI 154
Cdd:PLN02563 104 DVDTSKPKFYVLDMFPYPSGAgLHVGHPEGYTATDILARYKRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKITTLKNI 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 155 KHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEhGCSWRSGAKVE 234
Cdd:PLN02563 184 ARFRSQLKSLGFSYDWDREISTTEPEYYKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVD-GLSERGGHPVI 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 235 QKYLRQWFIKTTAYAKAMQDALADLpEW-YGIKGMQAHWIGDCVGCHLDF-TLKVHGQATGEKLTAYTATPEAIYGTSHV 312
Cdd:PLN02563 263 RKPMRQWMLKITAYADRLLEDLDDL-DWpESIKEMQRNWIGRSEGAELDFsVLDGEGKERDEKITVYTTRPDTLFGATYL 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 313 AISPSHRLLHGHSSL--KEAL--------------RMALVPGKD-CLTPVMAVNMLTQQEVPVVIlakAD-LEGSLDSK- 373
Cdd:PLN02563 342 VVAPEHPLLSSLTTAeqKEAVeeyvdaasrksdleRTELQKEKTgVFTGSYAINPATGEAIPIWV---ADyVLGSYGTGa 418
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 374 -IGIPSTSSEDTILAQTLGLAYSEVIETlPDGTER------------LSSSA---EFTGMTRQDAFLALTQKARGKRVGG 437
Cdd:PLN02563 419 iMAVPAHDTRDFEFAQKFDLPIKWVVKP-ADGNEDdaekaytgegviVNSSSsglDINGLSSKEAAKKVIEWLEETGNGK 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 438 DVTSDKLKDWLISRQRYWGTPIPIVHcPVCGPTPVPL--EDLPVTLPNIASF--TGKGGPPLAMASEWVNCSCPRCKGAA 513
Cdd:PLN02563 498 KKVNYKLRDWLFARQRYWGEPIPVVF-LEDSGEPVPVpeSDLPLTLPELDDFtpTGTGEPPLAKAVSWVNTVDPSSGKPA 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 514 KRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKL 593
Cdd:PLN02563 577 RRETNTMPQWAGSCWYYLRFMDPKNSNALVDKEKEKYWMPVDLYVGGAEHAVLHLLYARFWHKVLYDIGVVSTKEPFQCL 656
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 594 LAQGLIKGQ----TFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWE-----------------KMSKSKHNGVDPEE 652
Cdd:PLN02563 657 VNQGMILGEveytAFKDSDGEYVSADTADRLGELQQEKIPEEKVIKSGDsfvlkddpsirliarahKMSKSRGNVVNPDD 736
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 653 VVEQYGIDTIRLYILFAAPPEKDILWdvKTDALPGVLRWQQRLWTLttrFIEARASGKSPQPQLLSNKEKAEARKLWEYk 732
Cdd:PLN02563 737 VVSEYGADSLRLYEMFMGPLRDSKTW--STSGVEGVHRFLGRTWRL---VVGAPLPDGSFRDGTVVTDEEPSLEQLRLL- 810
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 733 NSVISQVTTHfTEDFSLNSAISQLMGLSNALSQASQsvilhSPefEDALCALMVMAAPLAPHVTSEIWaglalvprKLCA 812
Cdd:PLN02563 811 HKCIAKVTEE-IESTRFNTAISAMMEFTNAAYKWDK-----VP--REAIEPFVLLLSPYAPHLAEELW--------FRLG 874
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 813 HytwDASVLLQAWPAVDPEFLQQPEVVqMAVLINNKACGKIPVPqqVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSP 892
Cdd:PLN02563 875 H---SNSLAYEPWPEANPSYLVDDTVV-LPVQINGKTRGTIEVE--EGCSEDDAFALASQDEKLSKYLDGKEIKKRIYVP 948
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
83-678 |
4.73e-134 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 403.55 E-value: 4.73e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 83 KFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLD 162
Cdd:cd00812 1 KFYILVMFPYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAENAAIKIGRDPEDWTEYNIKKMKEQLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 163 RLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDpvdqtvlaneqvdehgcswrsgakveqKYLRQWF 242
Cdd:cd00812 81 RMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWC---------------------------KLLDQWF 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 243 IKT--TAYAKAMQDALADLPEWY-GIKGMQAHWIGdcvgchldftlkvhgqatgekltaytatpeaiygtshvaispshr 319
Cdd:cd00812 134 LKYseTEWKEKLLKDLEKLDGWPeEVRAMQENWIG--------------------------------------------- 168
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 320 llhghsslkealrmalvpgkdcltpvmavnmltqqevpvvilakadlegsldskigipstssedtilaqtlglaysevie 399
Cdd:cd00812 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 400 tlpdgterlsssaeftgmtrqdaflaltqkargkrvggdvtsdklkdwlISRQRYWGTPIPIvhcpvcgptpvpledlpv 479
Cdd:cd00812 169 -------------------------------------------------CSRQRYWGTPIPW------------------ 181
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 480 tlpniasftgkggpplamasewvncscprckgaakreTDTMDTFVDSAWYYFRYTDPHNPHSP------FNTAVADYWMP 553
Cdd:cd00812 182 -------------------------------------TDTMESLSDSTWYYARYTDAHNLEQPyegdleFDREEFEYWYP 224
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 554 VDLYIGGKEHAVMHLFYARFFSHFCHDQKMVkHREPFHKLLAQGLIKGQTfrlpsgqylqreevdltgsvpvhaktkekl 633
Cdd:cd00812 225 VDIYIGGKEHAPNHLLYSRFNHKALFDEGLV-TDEPPKGLIVQGMVLLEG------------------------------ 273
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 1565200264 634 evtwEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILW 678
Cdd:cd00812 274 ----EKMSKSKGNVVTPDEAIKKYGADAARLYILFAAPPDADFDW 314
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
57-846 |
2.14e-61 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 224.17 E-value: 2.14e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAE 136
Cdd:TIGR00422 8 HEVEKKWYKKWEKSGFFKPDGNSNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTDHAGIATQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 137 nAAVERNLHPQS-----------------WTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAY 199
Cdd:TIGR00422 88 -VKVEKKLGAEGktkhdlgreefrekiweWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVRLYEKGLIY 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 200 QKEALVNWDPVDQTVLANEQVDEHgcswrsgaKVEQKYlrqWFIKttaYakamqdALADLPEwygikgmqahwigdcvgc 279
Cdd:TIGR00422 167 RGEYLVNWDPKLNTAISDIEVEYK--------EVKGKL---YYIR---Y------PLANGSK------------------ 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 280 hldftlkvhgqatgEKLTAYTATPEAIYGTSHVAISPS---HRLLHGhsslKEalrmalvpgkdcltpvmAVNMLTQQEV 356
Cdd:TIGR00422 209 --------------DYLVVATTRPETMFGDTAVAVHPEderYKHLIG----KK-----------------VILPLTGRKI 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 357 PVVILAKADLE-GSLDSKIgIPSTSSEDTILAQTLGLaysEVIETLPDGTERLSSSAEFTGMTRQDA------------F 423
Cdd:TIGR00422 254 PIIADEYVDMEfGTGAVKV-TPAHDFNDYEWGKRHNL---EFINILDEDGLLNENAGKYQGLTRFEArkkivedlkeegL 329
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 424 L---------------------------------ALTQKARGKRVGGDVT-------------SDKLKDWLISRQRYWGT 457
Cdd:TIGR00422 330 LvkiephthnvgtcwrsgtvvepllskqwfvkveKLADKALEAAEEGEIKfvpkrmekrylnwLRNIKDWCISRQLIWGH 409
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 458 PIPIVHCPVCGPTPVPLEDLPVTLPNiasftgKGGPplamASEWvncscprckgaaKRETDTMDTFVDSAWYYFRYTDPH 537
Cdd:TIGR00422 410 RIPVWYCKECGEVYVAKEEPLPDDKT------NTGP----SVEL------------EQDTDVLDTWFSSSLWPFSTLGWP 467
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 538 NphspFNTAVADYWmPVDLYIGGKEHAVMHLFYARFFSHFCHDQKmvkhrePFHKLLAQGLIKGQTFRlpsgqylqreev 617
Cdd:TIGR00422 468 D----ETKDLKKFY-PTDLLVTGYDIIFFWVARMIFRSLALTGQV------PFKEVYIHGLVRDEQGR------------ 524
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 618 dltgsvpvhaktkeklevtweKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTdaLPGVLRWQQRLWT 697
Cdd:TIGR00422 525 ---------------------KMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPGDDINFDWKR--VESARNFLNKLWN 581
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 698 lTTRFIEARASGKSPQPQLLSNKEKAEaRKLWEYKNSVISQVTTHFtEDFSLNSAIS--------------------QLM 757
Cdd:TIGR00422 582 -ASRFVLMNLSDDLELSGGEEKLSLAD-RWILSKLNRTIKEVRKAL-DKYRFAEAAKalyefiwndfcdwyielvkyRLY 658
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 758 GLSNALSQASQSVILHspefedALCALMVMAAPLAPHVTSEIWAGLAlvprklcahyTWDASVLLQAWPAVDPEFLQQPE 837
Cdd:TIGR00422 659 NGNEAEKKAARDTLYY------VLDKALRLLHPFMPFITEEIWQHFK----------EGADSIMLQSYPVVDAEFVDEEA 722
|
....*....
gi 1565200264 838 VVQMAVLIN 846
Cdd:TIGR00422 723 EKAFELLKE 731
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
46-831 |
8.62e-57 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 210.05 E-value: 8.62e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 46 KWTKEYTLqtrKDVEKWWHQR-IKEQASKISEADKsKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVIN 124
Cdd:PRK13208 5 ELPKKYDP---EELEEKWQKIwEEEGTYKFDPDER-KPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 125 PMGWDAFGLPAEnAAVERNL----HPQS----------WTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFI 190
Cdd:PRK13208 81 PQGWDDNGLPTE-RKVEKYYgirkDDISreefielcreLTDEDEKKFRELWRRLGLSVDWSLEYQTISPEYRRISQKSFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 191 KLYEAGLAYQKEALVNWDPVDQTVLaneqvdehgcswrsgAKVEQKYLrqwfIKTTAYAkamqdaladlpewygikgmqa 270
Cdd:PRK13208 160 DLYKKGLIYRAEAPVLWCPRCETAI---------------AQAEVEYR----EREGKLN--------------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 271 hwigdcvgcHLDFTLKvhgqaTGEKLTAYTATPEAIYGTSHVAISPS---HRLLHGhsslkealRMALVPgkdcltpvma 347
Cdd:PRK13208 200 ---------YIKFPVE-----DGEEIEIATTRPELLPACVAVVVHPDderYKHLVG--------KTAIVP---------- 247
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 348 vnmLTQQEVPVVILAKADLE-GS---------------------LDSKIGIpstsSED---TILAQTL-GL----AYSEV 397
Cdd:PRK13208 248 ---LFGVEVPILADPLVDPDfGTgavmictfgdktdvtwwrelnLPTRIII----DEDgrmTEAAGKLaGLtieeARKKI 320
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 398 IETLPDG-----TERLSSSA----------EFTgMTRQ---------DAFLALTQKAR------GKR----VGGdvtsdk 443
Cdd:PRK13208 321 VEDLKSGgllgkQEPIKHNVkfcercdtplEIL-VTRQwfikvldlkEELLERGKEINwypehmRVRlenwIEG------ 393
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 444 LK-DWLISRQRYWGTPIPIVHCPVCGPTPVPLE-DLPVTlPNiasftgKGGPPLamasewvnCSCPRC-KGAAKRETDTM 520
Cdd:PRK13208 394 LNwDWCISRQRYFGTPIPVWYCKDCGHPILPDEeDLPVD-PT------KDEPPG--------YKCPQCgSPGFEGETDVM 458
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 521 DTFVDS---AWYYFRYTDPHNPHSP-FntavadywmPVDLYIGGkehavmH------LFYARFFSHFCHDQKmvkhrePF 590
Cdd:PRK13208 459 DTWATSsitPLIVTGWERDEDLFEKvF---------PMDLRPQG------HdiirtwLFYTILRAYLLTGKL------PW 517
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 591 HKLLAQGLIKGqtfrlPSGqylqreevdltgsvpvhaktkeklevtwEKMSKSKHNGVDPEEVVEQYGIDTIRLYILfAA 670
Cdd:PRK13208 518 KNIMISGMVLD-----PDG----------------------------KKMSKSKGNVVTPEELLEKYGADAVRYWAA-SA 563
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 671 PPEKDILWDVKTdaLPGVLRWQQRLWTLtTRFIEARASGKSPQPQLLSNK-EKAEARKLweykNSVISQVTTHFtEDFSL 749
Cdd:PRK13208 564 RLGSDTPFDEKQ--VKIGRRLLTKLWNA-SRFVLHFSADPEPDKAEVLEPlDRWILAKL----AKVVEKATEAL-ENYDF 635
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 750 NSAISQLM--------------------GLSNALSQASQSVILHSpefedALCALMVMAAPLAPHVTSEIWaglalvprk 809
Cdd:PRK13208 636 AKALEEIEsffwhvfcddylelvksrayGEDEEEEQKSARYTLYT-----VLDTLLRLLAPFLPFITEEVW--------- 701
|
890 900
....*....|....*....|..
gi 1565200264 810 lcaHYTWDASVLLQAWPAVDPE 831
Cdd:PRK13208 702 ---SWLYGGSVHRASWPEPDEE 720
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
82-678 |
1.21e-51 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 185.91 E-value: 1.21e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 82 PKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAaVERNL----------------- 144
Cdd:cd00817 1 PVFVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVV-VEKKLgiegktrhdlgreefle 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 145 HPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVdehg 224
Cdd:cd00817 80 KCWEWKEESGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 225 cSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD-LPEWYgikgmqahwigdcvgchldftlkvhgqatgekltaytatp 303
Cdd:cd00817 156 -CSRSGDVIEPLLKPQWFVKVKDLAKKALEAVKEgDIKFV---------------------------------------- 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 304 eaiygtshvaisPSHrllhghsslkealrmalvpgkdcltpvmavnmltqqevpvvilAKADLEGSLDSkigipstssed 383
Cdd:cd00817 195 ------------PER-------------------------------------------MEKRYENWLEN----------- 208
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 384 tilaqtlglaysevietlpdgterlsssaeftgmtrqdaflaltqkargkrvggdvtsdkLKDWLISRQRYWGTPIPIVH 463
Cdd:cd00817 209 ------------------------------------------------------------IRDWCISRQLWWGHRIPAWY 228
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 464 CPVCGP-TPVPLEDLPVTLPniasftgkggpplamasewVNCSCPRCKGAA-KRETDTMDTFVDSA-WyyfrytdphnPH 540
Cdd:cd00817 229 CKDGGHwVVAREEDEAIDKA-------------------APEACVPCGGEElKQDEDVLDTWFSSSlW----------PF 279
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 541 S----PFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKmvkhrePFHKLLAQGLIKGQtfrlpsgqylqree 616
Cdd:cd00817 280 StlgwPEETKDLKKFYPTSLLVTGHDIIFFWVARMIMRGLKLTGKL------PFKEVYLHGLVRDE-------------- 339
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1565200264 617 vdltgsvpvhaktkeklevTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILW 678
Cdd:cd00817 340 -------------------DGRKMSKSLGNVIDPLDVIDGYGADALRFTLASAATQGRDINL 382
|
|
| ileS |
TIGR00392 |
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ... |
61-833 |
2.39e-35 |
|
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ligase and is particularly closely related to the valyl tRNA synthetase. This model may recognize IleS from every species, including eukaryotic cytosolic and mitochondrial forms. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273054 [Multi-domain] Cd Length: 861 Bit Score: 144.82 E-value: 2.39e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 61 KWWHQRIKEqasKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAaV 140
Cdd:TIGR00392 18 FWQENDIFE---KVKKLNKGKPEFIFHDGPPYANGSIHLGHALNKILKDIILRYKTMQGFNVTRKPGWDTHGLPIEHK-V 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 141 ERNLHPQS------------------WTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKE 202
Cdd:TIGR00392 94 EKKLGISGkkeissleieefrekcreFALKQIEEQREQFQRLGVWGDWENPYKTMDPSYEESQWWLFKEAHEKGLLYRGL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 203 ALVNWDPVDQTVLANEQVDEHGCSWR-----------------SGAKVEQKYLRQWfiKTTAYAKAMQDALADLPEW-YG 264
Cdd:TIGR00392 174 KPVYWSPRCRTALAEAEVEYKENYKDvkdpsiyvkfpvkkdkkTYLKVKLSSLLIW--TTTPWTLPSNLAIAVHPDFeYA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 265 ---IKGMQAHWIG-----DCVGCHLDFTLKVHGQATGEKLTAYTATP------EAIYGTSHVAISPSHRLL--------- 321
Cdd:TIGR00392 252 lvqDNTKVEYFILakklvEKLYNKAGSDYEIIKTFKGSDLEGLEYEHplydfvSQLKEGAPVVIGGDHVTTedgtgivht 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 322 ---HGhsslKEALRMALVPGKDCLTPVMAVNMLTQQEVP----VVILAKADLEGSLDSKIgipstssedTILAQTLGLAY 394
Cdd:TIGR00392 332 apgHG----EEDYEIGKKYGLEVLSPVDEKGVYTEGVNDfqgrFVKDADKDIIKANKIII---------EQLKDKGLLLK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 395 SEVIE------------TLPDGTERLsssaeFTGMTR-QDAFLALTQK-----ARGK-RVGGDVTSdkLKDWLISRQRYW 455
Cdd:TIGR00392 399 AEKIThsyphcwrtktpVIYRATEQW-----FIKTKDiKDQMLEQIKKvnwvpEWGEgRFGNWLEN--RPDWCISRQRYW 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 456 GTPIPIVHCPVCGpTPVPLEDLPvTLPNIASFTGKGGPPLAMASE---WVNCSCPRCkGAAKRETDTMDTFVDS--AWYY 530
Cdd:TIGR00392 472 GIPIPIWYCEDTG-EPIVVGSIE-ELIELIELKGIDAWFEDLHRDfldKITLKSGDG-GEYRRVPDVLDVWFDSgsMPYA 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 531 FRytdphnpHSPFNTAVADYWMPVDLYIGGkehavmhlfyarffshfcHDQkmvkHREPFHKLLAQGLIkgqtfrlpsgq 610
Cdd:TIGR00392 549 SI-------HYPFENEKFKEVFPADFILEG------------------SDQ----TRGWFYSSLAIGTA----------- 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 611 ylqreevdLTGSVP-----VHAKTkekLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPpekdilWD---VKT 682
Cdd:TIGR00392 589 --------LFGQAPyknviTHGFT---LDEKGRKMSKSLGNVVDPLKVINKYGADILRLYVASSDP------WEdlrFSD 651
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 683 DALPGVLRWQQRLWTLTTRFIEARAS--GKSPQPQLLSNKEKAEARKLWEYK-NSVISQVTTHFtEDFSLNSAISQLMG- 758
Cdd:TIGR00392 652 EILKQVVEKYRKIRWNTYRFLLTYANldKFDPLFNSVAVEKFPEEDRWILSRlNSLVEEVNEAL-EKYNFHKVLRALQDf 730
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 759 ----LSN----------------ALSQASQSVILHspefedALCALMVMAAPLAPHVTSEIWAGLALVPRKlcahytwdA 818
Cdd:TIGR00392 731 iveeLSNwyiriirdrlyceakdNDKRAAQTTLYY------ALLTLVRLLAPFLPHTAEEIYQNLPGGEEE--------E 796
|
890
....*....|....*
gi 1565200264 819 SVLLQAWPAVDPEFL 833
Cdd:TIGR00392 797 SVHLNLWPEVDEEFI 811
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
61-679 |
2.40e-33 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 136.77 E-value: 2.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 61 KWWhqrIKEQASKIS-EADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAEnAA 139
Cdd:pfam00133 4 EFW---DEQGYFKPElEKRKGKPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTE-QV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 140 VERNLHPQ------------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQK 201
Cdd:pfam00133 80 VEKKLGIKekktrhkygreefrekcrEWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 202 EALVNWDPVDQTVLANeqvdehgcswrsgAKVEQKylrqwfikttayakamqdaladlpewygikgmqahwigDCVGCHL 281
Cdd:pfam00133 160 KKLVNWSPALNTALSN-------------LEVEYK--------------------------------------DVKGPSI 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 282 DFTLKVHGQAtGEKLTAYTATPEAIYGTSHVAISP------SHRLLHGHSSLKEALRMALVPGKDCLTP-------VMAV 348
Cdd:pfam00133 189 HVAFPLADDE-GASLVIWTTTPWTLPGNTAVAVNPefdyviTGEGYILAEALLKSLYKKGTDKKILEDFrgkelegKEAI 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 349 NMLTQQEVPVVILAKADLE-GSLDSKIGiPSTSSEDTILAQTLGLaysEVIETL-PDGTERlSSSAEFTGMTRQDAFLAL 426
Cdd:pfam00133 268 HPFVNREIPIITDDYVDMEfGTGAVHIA-PAHGENDYEVGQRHNL---EVINPVdDDGTFT-EEAPDFQGVYRFDARKKI 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 427 TQ--KARGKRVGGD-------------------------VTSDKLK-----------------------------DWLIS 450
Cdd:pfam00133 343 VEllTEKGLLLKIEpfthsypfcwrsgtpiipratpqwfVRMDELAdqaleavekvqfvpksgekryfnwlaniqDWCIS 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 451 RQRYWGTPIPI--------VHCPVCGPTPVPLEDLPVTlpNIASFTGKGGPPLAMAsewvncscprcKGAAKRETDTMDT 522
Cdd:pfam00133 423 RQRWWGHPIPAwvskdteeVVCRGELFELVAGRFEEEG--SIKWLHREAKDKLGYG-----------KGTLEQDEDVLDT 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 523 FVDSA-WYYfrytdpHNPHSPFNTAVA-DYWMPVDLYIGGKEhavMHLFYarFFSHFCHDQKMVKhREPFHKLLAQGLIk 600
Cdd:pfam00133 490 WFSSGsWPF------STLGWPFVNTEEfKKFFPADMLLEGSD---QTRGW--FYRMIMLSTALTG-SVPFKNVLVHGLV- 556
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1565200264 601 gqtfRLPSGQylqreevdltgsvpvhaktkeklevtweKMSKSKHNGVDPEEVVEQYGIDTIRLYILFaAPPEKDILWD 679
Cdd:pfam00133 557 ----RDEQGR----------------------------KMSKSLGNVIDPLDVIDKYGADALRLWLAN-SDYGRDINLS 602
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
83-678 |
4.05e-32 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 127.53 E-value: 4.05e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 83 KFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAA-------------VERNLHPQSW 149
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAerkggrkkktiwiEEFREDPKEF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 150 TQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEalvnwdpvdqtvlaneqvdehgcswRS 229
Cdd:cd00668 81 VEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGT-------------------------HP 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 230 GAKVEqkylrQWFIKTTAYAKAMQDAL---ADLPEWYgikgmqahwigdcvgchldftlkvhgqatgekltaytatpeai 306
Cdd:cd00668 136 VRITE-----QWFFDMPKFKEKLLKALrrgKIVPEHV------------------------------------------- 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 307 ygtshvaispshrllhghsslkealrmalvpgkdcltpvmavnmltqqevpvvilaKADLEGSLDSkigipstssedtil 386
Cdd:cd00668 168 --------------------------------------------------------KNRMEAWLES-------------- 177
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 387 aqtlglaysevietlpdgterlsssaeftgmtrqdaflaltqkargkrvggdvtsdkLKDWLISRQRYWGTPIPivhcpv 466
Cdd:cd00668 178 ---------------------------------------------------------LLDWAISRQRYWGTPLP------ 194
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 467 cgptpvpledlpvtlpniasftgkggpplamasewvncscprckgaakreTDTMDTFVDSAWYYFRYTdphnpHSPFNTA 546
Cdd:cd00668 195 --------------------------------------------------EDVFDVWFDSGIGPLGSL-----GYPEEKE 219
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 547 VADYWMPVDLYIGGKEHAVMHLfyarFFSHFCHdqKMVKHREPFHKLLAQGLIKGqtfrlPSGQylqreevdltgsvpvh 626
Cdd:cd00668 220 WFKDSYPADWHLIGKDILRGWA----NFWITML--VALFGEIPPKNLLVHGFVLD-----EGGQ---------------- 272
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1565200264 627 aktkeklevtweKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILW 678
Cdd:cd00668 273 ------------KMSKSKGNVIDPSDVVEKYGADALRYYLTSLAPYGDDIRL 312
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
57-845 |
1.42e-30 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 129.84 E-value: 1.42e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVEKWWHQRIKEQasKISEADKSKPKFYVLsMFPYP--SGKLHMGHVRVYTISDTIARFQKMRGMQVInpmgWdafgLP 134
Cdd:PRK05729 12 KEVEAKWYQKWEEK--GYFKPDDNSKKPFSI-VIPPPnvTGSLHMGHALNNTLQDILIRYKRMQGYNTL----W----LP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 135 -------AENAAVERNLHPQS-----------------WTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFI 190
Cdd:PRK05729 81 gtdhagiATQMVVERQLAAEGksrhdlgrekflekvweWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 191 KLYEAGLAYQKEALVNWDPVDQTVLANEQVdEHgcswrsgAKVEQKYlrqWFIKttayakamqdaladlpewYGIKGmqa 270
Cdd:PRK05729 161 RLYEKGLIYRGKRLVNWDPKLQTALSDLEV-EY-------KEVKGKL---WHIR------------------YPLAD--- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 271 hwigdcvgchldftlkvhgqaTGEKLTAYTATPEAIYGTSHVAISPS-HRLLHghsslkealrmaLVpGKDCLTPvmavn 349
Cdd:PRK05729 209 ---------------------GSDYLVVATTRPETMLGDTAVAVNPEdERYKH------------LI-GKTVILP----- 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 350 mLTQQEVPVVILAKADLE---GSLdsKIgipsTSSEDT---ILAQTLGLaysEVIETL-PDGTerLSSSA-EFTGMTRQD 421
Cdd:PRK05729 250 -LVGREIPIIADEYVDPEfgtGAV--KI----TPAHDPndfEVGKRHNL---PMINIMdEDGT--INENPgEYQGLDRFE 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 422 A------------------------------------------FLA---LTQKARGKRVGGDVT-------------SDK 443
Cdd:PRK05729 318 ArkaivadleelgllvkiephthsvghsdrsgvviepylsdqwFVKmkpLAKPALEAVENGEIKfvperwektyfhwMEN 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 444 LKDWLISRQRYWGTPIPIVHCP----VCGPTPVpledlpvtlpniasftgkggpplamasewvncsCPRCKGAAKRETDT 519
Cdd:PRK05729 398 IQDWCISRQLWWGHRIPAWYDEdgevYVGREEP---------------------------------EAREKALLTQDEDV 444
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 520 MDTFVDSA-WyyfrytdphnPHS----PFNTAVADYWMPVDLYIGGkehavmH--LFY--AR--FFSHFCHDQKmvkhre 588
Cdd:PRK05729 445 LDTWFSSAlW----------PFStlgwPEKTEDLKRFYPTSVLVTG------FdiIFFwvARmiMMGLHFTGQV------ 502
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 589 PFHKLLAQGLI---KGQtfrlpsgqylqreevdltgsvpvhaktkeklevtweKMSKSKHNGVDPEEVVEQYGIDTIRLY 665
Cdd:PRK05729 503 PFKDVYIHGLVrdeQGR------------------------------------KMSKSKGNVIDPLDLIDKYGADALRFT 546
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 666 ILFAAPPEKDILWDVKtdalpgvlRWQQ------RLWTlTTRFIEARASGKSPQPQLLSNKEKAEAR----KLweykNSV 735
Cdd:PRK05729 547 LAALASPGRDIRFDEE--------RVEGyrnfanKLWN-ASRFVLMNLEGADVGELPDPEELSLADRwilsRL----NRT 613
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 736 ISQVTTHFtEDFSLNSAISQLMG-----------------LSNALSQASQSVILHspefedALCALMVMAAPLAPHVTSE 798
Cdd:PRK05729 614 VAEVTEAL-DKYRFDEAARALYEfiwnefcdwylelakpvLQEAAKRATRATLAY------VLEQILRLLHPFMPFITEE 686
|
890 900 910 920
....*....|....*....|....*....|....*....|....*..
gi 1565200264 799 IWAGLalvprklcAHYTWDASVLLQAWPAVDPEFLQQPEvVQMAVLI 845
Cdd:PRK05729 687 LWQKL--------APLGIEESIMLAPWPEADEAIDEAAE-AEFEWLK 724
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
57-846 |
2.24e-29 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 125.93 E-value: 2.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVEKWWHQR-IKEQASKiSEADKSKPKFYVlsMFPYP--SGKLHMGHVRVYTISDTIARFQKMRGmqvinpmgWDAFGL 133
Cdd:COG0525 10 KEVEAKWYQYwEENGYFK-ADPDSDKEPFTI--VIPPPnvTGSLHMGHALNNTLQDILIRYKRMQG--------YNTLWQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 134 P-------AENAAVERNLHPQ-----------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLF 189
Cdd:COG0525 79 PgtdhagiATQAVVERQLAEEgksrhdlgrekflervwEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 190 IKLYEAGLAYQKEALVNWDPVDQTVLANEQVdEHgcswrsgaKVEQKYLrqWFIKttayakamqdaladlpewYGIKGMQ 269
Cdd:COG0525 159 VRLYEKGLIYRGKRLVNWDPKLKTALSDLEV-EH--------EEVKGHL--WHIR------------------YPLADGS 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 270 AHwigdcvgchldftLKVhgqatgekltaytAT--PEAIYGTSHVAISPS-----HrlLHGhsslkealRMALVPgkdcl 342
Cdd:COG0525 210 GY-------------IVV-------------ATtrPETMLGDTAVAVHPEderykH--LIG--------KTVILP----- 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 343 tpvmavnmLTQQEVPVVILAKADLE---GSLdsKIgipsTSSEDT---ILAQTLGLaysEVIETL-PDGTerLSSSA-EF 414
Cdd:COG0525 249 --------LVGREIPIIADEYVDPEfgtGAV--KI----TPAHDPndfEVGKRHNL---PMINILdEDGT--INENAgKY 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 415 TGMTRQDA------------------------------------------FLA---LTQKARgKRV-GGDVT-------- 440
Cdd:COG0525 310 RGLDRFEArkaivadleelgllvkvephkhsvghsdrsgtviepylsdqwFVKmkpLAKPAI-EAVeDGEIKfvperwek 388
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 441 -----SDKLKDWLISRQRYWGTPIPIVHCPvCGPTPVPLEDLPVtlpniasftgkggpplamasewvncsCPRCKGAA-K 514
Cdd:COG0525 389 tyfhwMENIRDWCISRQLWWGHRIPAWYCP-DGEVYVARTEPEA--------------------------CAKAGSVNlT 441
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 515 RETDTMDTFVDSA-WyyfrytdphnPHS----PFNTAVADYWMPVDLYIGGKEhavmHLFY--AR--FFS-HFchdqkmv 584
Cdd:COG0525 442 QDEDVLDTWFSSAlW----------PFStlgwPEKTEDLKYFYPTSVLVTGFD----IIFFwvARmiMMGlHF------- 500
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 585 KHREPFHKLLAQGLI---KGQtfrlpsgqylqreevdltgsvpvhaktkeklevtweKMSKSKHNGVDPEEVVEQYGIDT 661
Cdd:COG0525 501 TGEVPFKDVYIHGLVrdeQGR------------------------------------KMSKSKGNVIDPLDLIDKYGADA 544
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 662 IRLYILFAAPPEKDILWDVKtdalpgvlRWQQ------RLWTlTTRFIEARASGKSPQPQLLSNKEKAEAR----KLwey 731
Cdd:COG0525 545 LRFTLAALASPGRDIKFDEE--------RVEGyrnfanKLWN-ASRFVLMNLEGFDPGLDPDPEELSLADRwilsRL--- 612
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 732 kNSVISQVTTHFtEDFSLNSAIS--------------------QLMGLSNALSQASQSVILHspefedALCALMVMAAPL 791
Cdd:COG0525 613 -NKTIAEVTEAL-EKYRFDEAAQalydfvwnefcdwylelakpRLYGGDEAAKRETRATLVY------VLEQILRLLHPF 684
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*
gi 1565200264 792 APHVTSEIWAGLALVPRklcahytwDASVLLQAWPAVDPEFLQQPEVVQMAVLIN 846
Cdd:COG0525 685 MPFITEEIWQKLPPRKE--------GESIMLAPWPEADEELIDEEAEAEFEWLKE 731
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
57-845 |
9.60e-28 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 120.96 E-value: 9.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVEKWWHQ-RIKEqasKISEADKSKPKFYvlsmF----PYPSGKLHMGHVRVYTISDTIARFQKMRGMQVI-NPmGWDA 130
Cdd:COG0060 23 PEILKFWEEnDIYE---KSREARAGRPKFV----LhdgpPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPyVP-GWDC 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 131 FGLPAENAaVERNLHPQ-----------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYK--WtqYLFIK 191
Cdd:COG0060 95 HGLPIELK-VEKELGIKkkdiekvgiaefrekcrEYALKYVDEQREDFKRLGVWGDWDNPYLTMDPEYEEsiW--WALKK 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 192 LYEAGLAYQKEALVNWDPVDQTVLANeqvdehgcswrsgAKVEqkYlrqwfiK----TTAYAK-AMQDALADLPEwygik 266
Cdd:COG0060 172 LYEKGLLYKGLKPVPWCPRCGTALAE-------------AEVE--Y------KdvtsPSIYVKfPVKDEKALLLL----- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 267 gmqahwigdcvgchldftlkvhgqaTGEKLTAYTATP-------------EAIYgtSHVAISPSHRLLhghsslkealrM 333
Cdd:COG0060 226 -------------------------EDAYLVIWTTTPwtlpanlavavhpDIDY--VLVEVTGGERLI-----------L 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 334 AlvpgKDCLTPVMAVNMLTQQEVpvviLAK---ADLEG-------------------------SLDSKIGI----PSTSS 381
Cdd:COG0060 268 A----EALVEAVLKELGIEDYEV----LATfkgAELEGlryehpfyyvvgydrahpvilgdyvTTEDGTGIvhtaPGHGE 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 382 EDTILAQTLGLaysEVIETL-PDG--TERLSssaEFTGMTRQDAFLALTQ--KARGK----------------------- 433
Cdd:COG0060 340 DDFEVGKKYGL---PVLNPVdDDGrfTEEAP---LFAGLFVKDANPAIIEdlKERGAllarekithsyphcwrcktpliy 413
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 434 --------RVggdvtsDKLK-----------------------------DWLISRQRYWGTPIPIVHCPVCGpTPVPLED 476
Cdd:COG0060 414 ratpqwfiSM------DKLRdraleaiekvnwipewgegrfgnmlenrpDWCISRQRYWGVPIPIWVCEDCG-ELHRTEE 486
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 477 LpvtlpnIAS----FTGKGgpplamASEWVN-----------CSCPRCKGAAKRETDTMDTFVDS--AWYyfrytdphnp 539
Cdd:COG0060 487 V------IGSvaelLEEEG------ADAWFEldlhrpfldetLKCPKCGGTMRRVPDVLDVWFDSgsMHF---------- 544
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 540 hspfntAV----ADYWMPVDLYIGGkehavmhlfyarffshfcHDQkmvkHREPFHKLLAQGLIkgqtfrlpsgqylqre 615
Cdd:COG0060 545 ------AVlenrEELHFPADFYLEG------------------SDQ----TRGWFYSSLLTSTA---------------- 580
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 616 evdLTGSVP-----VH-----AKTKeklevtweKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPE-----KDILWDV 680
Cdd:COG0060 581 ---LFGRAPyknvlTHgfvldEDGR--------KMSKSLGNVVDPQEVIDKYGADILRLWVASSDYWGdlrfsDEILKEV 649
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 681 KTdalpgVLRwqqRLWTlTTRFIEARASGKSPQPQLLSNKEKAE------ARkLweykNSVISQVTTHFtEDFSLNSAIS 754
Cdd:COG0060 650 RD-----VYR---RLRN-TYRFLLANLDDFDPAEDAVPYEDLPEldrwilSR-L----NELIKEVTEAY-DNYDFHRAYR 714
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 755 QLMG-LSNALS---------------------QASQSVILHspefedALCALMVMAAPLAPHVTSEIWAGLalvPRKLca 812
Cdd:COG0060 715 ALHNfCVEDLSnwyldiskdrlyteaadsldrRAAQTTLYE------VLETLVRLLAPILPFTAEEIWQNL---PGEA-- 783
|
970 980 990
....*....|....*....|....*....|...
gi 1565200264 813 hytwDASVLLQAWPAVDPEFLQQPEVVQMAVLI 845
Cdd:COG0060 784 ----EESVHLADWPEVDEELIDEELEAKWDLVR 812
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
678-803 |
9.89e-27 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 105.38 E-value: 9.89e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 678 WDvkTDALPGVLRWQQRLWTLTTRFIEARASGKSPqpqllsNKEKAEARKLWEYKNSVISQVTTHFtEDFSLNSAISQLM 757
Cdd:cd07958 1 WS--DSGVEGAYRFLNRVWRLVTELAEALAAPAAA------AELSEEDKELRRKLHKTIKKVTEDI-ERLRFNTAIAALM 71
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1565200264 758 GLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGL 803
Cdd:cd07958 72 ELVNALYKYKKKDAQHAAVLREALETLVLLLAPFAPHIAEELWEEL 117
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
57-829 |
1.27e-24 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 110.85 E-value: 1.27e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVEKWWHQRIKEQAS-KISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLpA 135
Cdd:PRK14900 22 REVEARWYPFWQERGYfHGDEHDRTRPPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPGTDHAGI-A 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 136 ENAAVERNLHPQ------------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGL 197
Cdd:PRK14900 101 TQMIVEKELKKTekksrhdlgreaflervwAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFVRLHEEGL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 198 AYQKEALVNWDPVDQTVLANEQVdEH-----GCSWRSGAKVEQKyLRQWFIKTTAYAKAMQD-ALADLPEwygikgmqAH 271
Cdd:PRK14900 181 IYREKKLINWCPDCRTALSDLEV-EHeeahqGELWSFAYPLADG-SGEIVVATTRPETMLGDtAVAVHPL--------DP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 272 WIGDCVGCHLdfTLKVHGQATGEKLTAYTATPEaiYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDC-LT----PVM 346
Cdd:PRK14900 251 RYMALHGKKV--RHPITGRTFPIVADAILVDPK--FGTGAVKVTPAHDFNDFEVGKRHGLEMITVIGPDGrMTaeagPLA 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 347 AVNML-TQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPdgteRLSSSAEFTGMTR------ 419
Cdd:PRK14900 327 GLDRFeARKEVKRLLAEQGLDRGAKPHVLPLGRCQRSATILEPLLSDQWYVRIEPLA----RPAIEAVEQGRTRfipeqw 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 420 QDAFLALTQkargkrvggdvtsdKLKDWLISRQRYWGTPIPIVHCPVCGPTpvpledlpvtlpniasftgkggpplaMAS 499
Cdd:PRK14900 403 TNTYMAWMR--------------NIHDWCISRQLWWGHQIPAWYCPDGHVT--------------------------VAR 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 500 EwVNCSCPRCKGAAKRE-TDTMDTFVDSAWYYFRYTDphnphSPFNTAVADYWMPVDLYIGGkeHAVMHLFYARFFS--- 575
Cdd:PRK14900 443 E-TPEACSTCGKAELRQdEDVLDTWFSSGLWPFSTMG-----WPEQTDTLRTFYPTSVMETG--HDIIFFWVARMMMmgl 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 576 HFCHDQkmvkhrePFHkllaqglikgqtfrlpsgqylqreevdltgSVPVHAKTKEKlevTWEKMSKSKHNGVDPEEVVE 655
Cdd:PRK14900 515 HFMGEV-------PFR------------------------------TVYLHPMVRDE---KGQKMSKTKGNVIDPLVITE 554
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 656 QYGIDTIRLYILFAAPPEKDIlwDVKTDALPGVLRWQQRLW-------------------------TLTTRFIEARAsgk 710
Cdd:PRK14900 555 QYGADALRFTLAALTAQGRDI--KLAKERIEGYRAFANKLWnasrfalmnlsgyqergedparlarTPADRWILARL--- 629
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 711 spQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTeDFSLNSAISQLMGLSNALSQASQSVILHSpefedaLCALMVMAAP 790
Cdd:PRK14900 630 --QRAVNETVEALEAFRFNDAANAVYAFVWHELC-DWYIELAKEALASEDPEARRSVQAVLVHC------LQTSYRLLHP 700
|
810 820 830
....*....|....*....|....*....|....*....
gi 1565200264 791 LAPHVTSEIWAGLalvpRKLCAHYTWDASVLLQAWPAVD 829
Cdd:PRK14900 701 FMPFITEELWHVL----RAQVGASAWADSVLAAEYPRKG 735
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
82-262 |
1.06e-22 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 103.27 E-value: 1.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 82 PKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQL 161
Cdd:COG0143 1 KKFLVTTAIPYANGPPHIGHLYTYIPADILARYQRLRGHDVLFVTGTDEHGTKIELAAEKEGITPQELVDRIHAEFKELF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 162 DRLGLcfSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLA------------NEQVDEHGC---- 225
Cdd:COG0143 81 EKLGI--SFDNFIRTTSPEHKELVQEIFQRLYDNGDIYKGEYEGWYCPECERFLPdryvegtcpkcgAEDAYGDQCencg 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1565200264 226 ------------SWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEW 262
Cdd:COG0143 159 atleptelinprSAISGAPPELREEEHYFFRLSKYQDRLLEWIEENPDI 207
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
83-216 |
2.18e-22 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 99.14 E-value: 2.18e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 83 KFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLD 162
Cdd:cd00814 1 KVLITTALPYVNGVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEEEGVTPQELCDKYHEIFKDLFK 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1565200264 163 RLGlcFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLA 216
Cdd:cd00814 81 WLN--ISFDYFIRTTSPRHKEIVQEFFKKLYENGYIYEGEYEGLYCVSCERFLP 132
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
82-676 |
3.42e-20 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 93.07 E-value: 3.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 82 PKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAEnAAVERNL----------------- 144
Cdd:cd00818 1 PEFVFHDGPPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIE-LKVEKELgisgkkdiekmgiaefn 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 145 -HPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWdPvdqtvlaneqvdeh 223
Cdd:cd00818 80 aKCREFALRYVDEQEEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW-P-------------- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 224 gcswrsgakVEQKYLRQWFIKTTAYAKAMQDALadlpewygikgMQAHWIgdcvgchldftlkvhgqatgekltaytatP 303
Cdd:cd00818 145 ---------LIYRATPQWFIRVTKIKDRLLEAN-----------DKVNWI-----------------------------P 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 304 EAIYgtshvaispsHRLLhghsslkealrmalvpgkdcltpvmavNMLtqqevpvvilakadlegsldskigipstssed 383
Cdd:cd00818 176 EWVK----------NRFG---------------------------NWL-------------------------------- 186
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 384 tilaqtlglaysevietlpdgterlsssaeftgmtrqdaflaltqkargkrvggdvtsDKLKDWLISRQRYWGTPIPIVH 463
Cdd:cd00818 187 ----------------------------------------------------------ENRRDWCISRQRYWGTPIPVWY 208
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 464 CPVCGPTPVpledlpvtlpniasftgkggpplamasewvncscprckgaaKRETDTMDTFVDS--AWYYFRytdphnpHS 541
Cdd:cd00818 209 CEDCGEVLV-----------------------------------------RRVPDVLDVWFDSgsMPYAQL-------HY 240
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 542 PFNTAVADYWMPVDLYIGGkehavmhlfyarffshfcHDQkmvkHREPFHKLLAQGLIkgqtfrlpsgqylqreevdLTG 621
Cdd:cd00818 241 PFENEDFEELFPADFILEG------------------SDQ----TRGWFYSLLLLSTA-------------------LFG 279
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 622 SVP-----VHAKTkekLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDI 676
Cdd:cd00818 280 KAPyknviVHGFV---LDEDGRKMSKSLGNYVDPQEVVDKYGADALRLWVASSDVYAEDL 336
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
84-221 |
2.42e-19 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 91.20 E-value: 2.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 84 FYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDR 163
Cdd:pfam09334 1 ILVTTALPYANGPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAEKEGITPEELVDRYHEIHREDFKK 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1565200264 164 LGLcfSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVD 221
Cdd:pfam09334 81 FNI--SFDDYGRTTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDERFLPDRYVE 136
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
83-262 |
3.18e-18 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 88.79 E-value: 3.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 83 KFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLD 162
Cdd:PRK11893 2 KFYITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFFLTGTDEHGQKIQRKAEEAGISPQELADRNSAAFKRLWE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 163 RLGlcFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEAL--------VNWDPvdqtvlaNEQVDEHGCSWRSGAKVE 234
Cdd:PRK11893 82 ALN--ISYDDFIRTTDPRHKEAVQEIFQRLLANGDIYLGKYEgwycvrceEFYTE-------SELIEDGYRCPPTGAPVE 152
|
170 180
....*....|....*....|....*...
gi 1565200264 235 QKYLRQWFIKTTAYAKAMQDALADLPEW 262
Cdd:PRK11893 153 WVEEESYFFRLSKYQDKLLELYEANPDF 180
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
97-223 |
3.98e-17 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 86.46 E-value: 3.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 97 LHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLP----AENAA--------VERNLH--PQSWTQS-----NI--- 154
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAFHVTGTPilgiAERIArgdpetieLYKSLYgiPEEELEKfkdpeYIvey 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1565200264 155 --KHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVlaneqVDEH 223
Cdd:PRK12300 81 fsEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNP-----VGDH 146
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
57-221 |
4.18e-17 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 86.60 E-value: 4.18e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 57 KDVE----KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFG 132
Cdd:PTZ00419 31 KEVEsgwyEWWEKSGFFKPAEDAKSLNSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDETLWVPGTDHAG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 133 LpAENAAVERNLHPQS------------------WTQ---SNIKhmrKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIK 191
Cdd:PTZ00419 111 I-ATQVVVEKKLMKEEnktrhdlgreeflkkvweWKDkhgNNIC---NQLRRLGSSLDWSREVFTMDEQRSKAVKEAFVR 186
|
170 180 190
....*....|....*....|....*....|
gi 1565200264 192 LYEAGLAYQKEALVNWDPVDQTVLANEQVD 221
Cdd:PTZ00419 187 LYEDGLIYRDTRLVNWCCYLKTAISDIEVE 216
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
59-221 |
3.23e-14 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 77.25 E-value: 3.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 59 VEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLpAENA 138
Cdd:PLN02381 105 VEKSWYAWWEKSGYFGADAKSSKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPGVDHAGI-ATQV 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 139 AVERNLHPQ------------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQ 200
Cdd:PLN02381 184 VVEKKLMRErhltrhdigreefvsevwKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLIYR 263
|
170 180
....*....|....*....|.
gi 1565200264 201 KEALVNWDPVDQTVLANEQVD 221
Cdd:PLN02381 264 DIRLVNWDCTLRTAISDVEVD 284
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
48-837 |
1.87e-13 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 74.81 E-value: 1.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 48 TKEYTLQtrkdveKWWHQRikEQASKISEADKSKPkFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMG 127
Cdd:PLN02843 7 TREPEIQ------KLWEEN--QVYKRVSDRNNGES-FTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 128 WDAFGLPAE-------NAAVERNLHP-------QSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLY 193
Cdd:PLN02843 78 WDCHGLPIElkvlqslDQEARKELTPiklrakaAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 194 EAGLAYQKEALVNWDPVDQTVLANEQVDehgcsWRSGAKVEQKYLrqwFIKTTAYAKAMQDALADLpewygIKGMQ-AHW 272
Cdd:PLN02843 158 LNGYIYRGRKPVHWSPSSRTALAEAELE-----YPEGHVSKSIYV---AFPVVSPSETSPEELEEF-----LPGLSlAIW 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 273 ----------IGDCVGCHLDFTLkVHGQATGEKLTAYTATPEAIYGtsHVAISPSHRLLHGHSSLKEALR---------M 333
Cdd:PLN02843 225 tttpwtmpanAAVAVNDKLQYSV-VEVQSFSEDESTSGGNKKKRPG--NVLKEQQKLFLIVATDLVPALEakwgvklvvL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 334 ALVPGKDcLTPVMAVNMLTQQEVPVVI-------------LAKADLEGSLD----SKIGIPSTSSED-----TILA---- 387
Cdd:PLN02843 302 KTFPGSD-LEGCRYIHPLYNRESPVVIggdyittesgtglVHTAPGHGQEDyitgLKYGLPLLSPVDdagkfTEEAgqfs 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 388 --QTLGLAYSEVIETLPD---------------------------GTERLSSSAE-FtgmtRQDAFLALTQ----KARG- 432
Cdd:PLN02843 381 glSVLGEGNAAVVEALDEagsllmeeayghkypydwrtkkptifrATEQWFASVEgF----RQAALDAIDKvkwiPAQGe 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 433 KRVGGDVTSDklKDWLISRQRYWGTPIPIVHCPvcgPTPVPLEDlPVTLPNIASFTGKGG-------------PPL--AM 497
Cdd:PLN02843 457 NRIRAMVSGR--SDWCISRQRTWGVPIPVFYHV---ETKEPLMN-EETIAHVKSIVAQKGsdawwymdvedllPEKyrDK 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 498 ASEWVncscprckgaakRETDTMDTFVDS--AWyyfrytdphnphSPFNTAVADYWMPVDLYIGGKehavmhlfyarffs 575
Cdd:PLN02843 531 ASDYE------------KGTDTMDVWFDSgsSW------------AGVLGSREGLSYPADLYLEGS-------------- 572
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 576 hfchDQkmvkHREPFH-KLLAQGLIKGQTfrlPSGQYLQReevdltGSVpvhaktkekLEVTWEKMSKSKHNGVDPEEVV 654
Cdd:PLN02843 573 ----DQ----HRGWFQsSLLTSVATKGKA---PYKSVLTH------GFV---------LDEKGFKMSKSLGNVVDPRLVI 626
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 655 E---------QYGIDTIRLYILFAappekdilwDVKTDALPGVLRWQQ-----RLWTLTTRFI-----EARASGKSPQPQ 715
Cdd:PLN02843 627 EggknqkqepAYGADVLRLWVASV---------DYTGDVLIGPQILKQmsdiyRKLRGTLRYLlgnlhDWKPDNAVPYED 697
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 716 L----------LSNKEKAEARKLWEYKNSVISQVTTHFT----EDFSLNSAISQLM--GLSNALSQASQSVILHspefed 779
Cdd:PLN02843 698 LpsidkyalfqLENVVNEIEESYDNYQFFKIFQILQRFTivdlSNFYLDVAKDRLYvgGTTSFTRRSCQTVLAA------ 771
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*...
gi 1565200264 780 ALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAhytwdASVLLQAWPAVDPEFLQQPE 837
Cdd:PLN02843 772 HLLSLLRAIAPILPHLAEDAWQNLPFQEDGSAA-----ESVFEAGWPTPNEEWLSFPA 824
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
49-461 |
5.97e-13 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 73.05 E-value: 5.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 49 KEYTLQTRKDVEKWWhqriKEQASKISEADKSKPKFyVLSMfPYP--SGKLHMGHVRVYTISDTIARFQKMRGMQVINPM 126
Cdd:PLN02943 59 KSFDFTSEERIYNWW----ESQGYFKPNFDRGGDPF-VIPM-PPPnvTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIP 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 127 GWDAFGLpAENAAVERNLHPQ-----------------SWTQSNIKHMRKQLDRLGLCFSWDREITTcLPDYYKWTQY-L 188
Cdd:PLN02943 133 GTDHAGI-ATQLVVEKMLASEgikrtdlgrdeftkrvwEWKEKYGGTITNQIKRLGASCDWSRERFT-LDEQLSRAVVeA 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 189 FIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEhgcSWRSGAKVEQKYlrqwfikttayakamqdaladlpewygikgm 268
Cdd:PLN02943 211 FVRLHEKGLIYQGSYMVNWSPNLQTAVSDLEVEY---SEEPGTLYYIKY------------------------------- 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 269 qahwigdcvgchldftlKVHGQaTGEKLTAYTATPEAIYGTSHVAISPSHRLLHghsslKEALRMALVPgkdcltpvmav 348
Cdd:PLN02943 257 -----------------RVAGG-SEDFLTIATTRPETLFGDVAIAVNPEDDRYS-----KYIGKMAIVP----------- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 349 nMLTQQEVPVVILAKADLE-GSLDSKIgIPSTSSEDTILAQTLGLAYSEVIETlpDGT-------------ERLSSSAEF 414
Cdd:PLN02943 303 -MTYGRHVPIIADRYVDKDfGTGVLKI-SPGHDHNDYLLARKLGLPILNVMNK--DGTlnevaglywfearEKLWSDLEE 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 415 TGMT--RQDAFLALTQKARGKRVGGDVTSDK--------------------------------------LKDWLISRQRY 454
Cdd:PLN02943 379 TGLAvkKEPHTLRVPRSQRGGEVIEPLVSKQwfvtmeplaekalkavengeltiiperfekiynhwlsnIKDWCISRQLW 458
|
....*..
gi 1565200264 455 WGTPIPI 461
Cdd:PLN02943 459 WGHRIPV 465
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
79-196 |
1.38e-11 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 68.29 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 79 KSKPKFYVLSMFPYPSGKLHMGHVrvYT--ISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKH 156
Cdd:PRK12267 1 MMKKTFYITTPIYYPNGKPHIGHA--YTtiAADALARYKRLQGYDVFFLTGTDEHGQKIQQAAEKAGKTPQEYVDEISAG 78
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1565200264 157 MRKQLDRLGLcfSWDREITTCLPDYYKWTQYLFIKLYEAG 196
Cdd:PRK12267 79 FKELWKKLDI--SYDKFIRTTDERHKKVVQKIFEKLYEQG 116
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
733-849 |
1.06e-10 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 60.49 E-value: 1.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 733 NSVISQVTTHFtEDFSLNSAISQLM-GLSNALS----QASQSVILHSPEFEDA-------LCALMVMAAPLAPHVTSEIW 800
Cdd:pfam08264 9 NKLIKEVTEAY-ENYRFNTAAQALYeFFWNDLSdwylELIKDRLYGEEPDSRAqttlyevLETLLRLLAPFMPFITEELW 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1565200264 801 AGLalvprklcahytwdaSVLLQAWPAV----DPEFLQQPEVVQMAVLINNKA 849
Cdd:pfam08264 88 QKE---------------SIHLAPWPEDaeleEAELEEAFELRQEIVQAIRKL 125
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
91-216 |
5.30e-10 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 63.25 E-value: 5.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 91 PYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTqSNIKHMRKQ-LDRLGLCF- 168
Cdd:PRK00133 11 PYANGPIHLGHLVEYIQADIWVRYQRMRGHEVLFVCADDAHGTPIMLKAEKEGITPEELI-ARYHAEHKRdFAGFGISFd 89
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1565200264 169 SWDReitTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLA 216
Cdd:PRK00133 90 NYGS---THSEENRELAQEIYLKLKENGYIYEKTIEQLYDPEKGMFLP 134
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
271-430 |
4.70e-09 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 56.79 E-value: 4.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 271 HWIGDCVGCHLDFtlKVHGqaTGEKLTAYTATPEAIYGTSHVAISPSHRL--------------LHGHSSLKEALRMALV 336
Cdd:pfam13603 2 NWIGRSEGAEITF--PVEG--TDEKIEVFTTRPDTLMGVTFVALAPEHPLveklaeknpevaafIEECKNTSEIERTSET 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 337 PGKD-CLTPVMAVNMLTQQEVPVVIlakAD---LEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIE------TLPDGTE 406
Cdd:pfam13603 78 KEKEgVFTGLYAIHPITGEKIPIWI---ANfvlMEYGTGAVMAVPAHDQRDFEFAKKYNLPIKPVIQpedgdlDLDIMTE 154
|
170 180 190
....*....|....*....|....*....|
gi 1565200264 407 ------RLSSSAEFTGMTRQDAFLALTQKA 430
Cdd:pfam13603 155 ayteegILVNSGEFDGLDSEEAKEAIIKKL 184
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
68-200 |
5.23e-08 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 57.04 E-value: 5.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 68 KEQASKiseaDKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENaAVERNLhpq 147
Cdd:PLN02882 28 KTQLKR----TEGLPEYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGWDCHGLPVEY-EIDKKL--- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 148 swtqsNIKHmRKQLDRLGL------CFS--------WDREITTC-----LPDYYK----------WtqYLFIKLYEAGLA 198
Cdd:PLN02882 100 -----GIKR-RDDVLKMGIdkyneeCRSivtryskeWEKTVTRTgrwidFENDYKtmdpkfmesvW--WVFKQLFEKGLV 171
|
..
gi 1565200264 199 YQ 200
Cdd:PLN02882 172 YK 173
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
445-667 |
2.48e-07 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 54.97 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 445 KDWLISRQRYWGTPIPI-----VHCPVCGPTPVPLEDLPvTLPNIASF-------------TGKGGPPLAMASEWVNCsc 506
Cdd:PTZ00427 569 KDWCISRNRYWGTPIPIwadekMETVICVESIKHLEELS-GVKNINDLhrhfidhieiknpKGKTYPKLKRIPEVFDC-- 645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 507 prckgaakretdtmdtfvdsaWYYFRYTDPHNPHSPFNTAVADYW--MPVDLYIGGKEHAVMHLFYARFFSHFCHDqkmv 584
Cdd:PTZ00427 646 ---------------------WFESGSMPYAKVHYPFSTEKEDFHkiFPADFIAEGLDQTRGWFYTLLVISTLLFD---- 700
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 585 khREPFHKLLAQGLIkgqtfrlpsgqylqreevdltgsvpvhaktkekLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRL 664
Cdd:PTZ00427 701 --KAPFKNLICNGLV---------------------------------LASDGKKMSKRLKNYPDPLYILDKYGADSLRL 745
|
...
gi 1565200264 665 YIL 667
Cdd:PTZ00427 746 YLI 748
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
638-671 |
2.62e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 54.42 E-value: 2.62e-07
10 20 30
....*....|....*....|....*....|....
gi 1565200264 638 EKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAP 671
Cdd:PRK12267 298 GKMSKSKGNVVDPEELVDRYGLDALRYYLLREVP 331
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
53-139 |
4.16e-06 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 50.84 E-value: 4.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 53 LQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFG 132
Cdd:PLN02959 16 LEIEVAVQKWWEEEKVFEAEAGDEPPKPGEKFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRLRGANVLLPFAFHCTG 95
|
....*..
gi 1565200264 133 LPAENAA 139
Cdd:PLN02959 96 MPIKASA 102
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
445-667 |
9.28e-06 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 49.72 E-value: 9.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 445 KDWLISRQRYWGTPIPIVHCP-----VCGPTPVPLEDLP--------------VTLPniaSFTGKGGPPLamasewvncs 505
Cdd:PLN02882 465 RDWAVSRSRFWGTPLPIWISDdgeevVVIGSIAELEKLSgvkvtdlhrhfidhITIP---SSRGPEFGVL---------- 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 506 cprckgaaKRETDTMDTFVDSAWYYFRYTdphnpHSPFNTavadywmpvdlyiggKEhavmhLFYARFFSHF---CHDQK 582
Cdd:PLN02882 532 --------RRVDDVFDCWFESGSMPYAYI-----HYPFEN---------------KE-----LFEKNFPADFvaeGLDQT 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 583 mvkhREPFHKL--LAQGLIKGQTFRlpsgqylqreEVDLTGSVpvhaktkekLEVTWEKMSKSKHNGVDPEEVVEQYGID 660
Cdd:PLN02882 579 ----RGWFYTLmvLSTALFDKPAFK----------NLICNGLV---------LAEDGKKMSKSLKNYPDPNEVIDKYGAD 635
|
....*..
gi 1565200264 661 TIRLYIL 667
Cdd:PLN02882 636 ALRLYLI 642
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
98-202 |
1.40e-04 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 45.48 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 98 HMGHVRVYTISDTIARFQKMRGMQV------------INpmgwdafglpaeNAAVERNLHPQSWTQSNIKHMRKQLDRLG 165
Cdd:COG0215 37 HIGHARTFVVFDVLRRYLRYLGYKVtyvrnitdvddkII------------KRAAEEGESIWELAERYIAAFHEDMDALG 104
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1565200264 166 lcfswdreittCL-PDYY-KWTQYL-----FIK-LYEAGLAYQKE 202
Cdd:COG0215 105 -----------VLpPDIEpRATEHIpemieLIErLIEKGHAYEAD 138
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
589-824 |
3.37e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 44.37 E-value: 3.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 589 PFHKLLAQGLIKGQTFRLPSgqylqreevdltgSVPVHaktkEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILF 668
Cdd:PRK00133 296 YFHTLFWPAMLEGAGYRLPT-------------NVFAH----GFLTVEGAKMSKSRGTFIWARTYLDHLDPDYLRYYLAA 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 669 AAPP-EKDIL--WD-----VKTDaLPGVL-----RwqqrlwTLTtrFIEARASGKSPqpqllsnkEKAEARKLWEYKNSV 735
Cdd:PRK00133 359 KLPEtIDDLDfnWEdfqqrVNSE-LVGKVvnfasR------TAG--FINKRFDGKLP--------DALADPELLEEFEAA 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 736 ISQVTTHFtEDFSLNSAISQLMGLS---NALSQASQ--SVILHSPEFEDALC--------ALMVMAAPLAPHVTSEIWAG 802
Cdd:PRK00133 422 AEKIAEAY-EAREFRKALREIMALAdfaNKYVDDNEpwKLAKQDGERLQAVCsvglnlfrALAIYLKPVLPELAERAEAF 500
|
250 260
....*....|....*....|..
gi 1565200264 803 LALVPrklcahYTWDASVLLQA 824
Cdd:PRK00133 501 LNLEE------LTWDDAQQPLA 516
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
70-273 |
1.95e-03 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 42.01 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 70 QASKISEADKskpkFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQS- 148
Cdd:PLN02224 61 QESTVDEADT----FVLTTPLYYVNAPPHMGSAYTTIAADSIARFQRLLGKKVIFITGTDEHGEKIATSAAANGRNPPEh 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1565200264 149 --WTQSNIKHMRKQLDrlglcFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQK--EAL--VNWDPVDQtvlANEQVDE 222
Cdd:PLN02224 137 cdIISQSYRTLWKDLD-----IAYDKFIRTTDPKHEAIVKEFYARVFANGDIYRAdyEGLycVNCEEYKD---EKELLEN 208
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1565200264 223 HGCSWRSGAKVEQKYlRQWFIKTTAYAKAMQDALADLPEW----YGIKGMQAhWI 273
Cdd:PLN02224 209 NCCPVHQMPCVARKE-DNYFFALSKYQKPLEDILAQNPRFvqpsYRLNEVQS-WI 261
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
638-667 |
2.17e-03 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 41.63 E-value: 2.17e-03
10 20 30
....*....|....*....|....*....|
gi 1565200264 638 EKMSKSKHNGVDPEEVVEQYGIDTIRLYIL 667
Cdd:COG0215 264 EKMSKSLGNFFTVRDLLKKYDPEVLRFFLL 293
|
|
| |
