pheromone receptor mating-type A2, partial [Microbotryum violaceum]
Protein Classification
7tmD_STE3 domain-containing protein( domain architecture ID 11606510)
7tmD_STE3 domain-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| 7tmD_STE3 | cd14966 | fungal a-factor pheromone receptor STE3, member of the class D family of seven-transmembrane G ... |
8-245 | 1.84e-83 | ||||
fungal a-factor pheromone receptor STE3, member of the class D family of seven-transmembrane G protein-coupled receptors; This subfamily represents the a-factor pheromone receptor encoded by the STE3 gene, which is required for pheromone sensing and mating in haploid cells of the yeast Saccharomyces cerevisiae. The STE3-encoded seven-transmembrane domain receptor is a member of the class D GPCRs. Class D receptors are composed of two major subfamilies: Ste2 and Ste3. These two GPCRs (Ste2 and Ste3) sense the polypeptide mating pheromones, alpha-factor and a-factor, which activate a G protein-coupled receptors on the surface of the opposite yeast-mating haploid-types (MATa and MAT-alpha), respectively. Activation of these receptors by pheromones leads to activation of the mitogen-activated protein kinase (MAPK) signal transduction cascades, G1 cell cycle arrest, and polarized cell growth in the direction of the partner cell (a process called shmooing), which ultimately induces cell-cell fusion and the formation of a diploid zygote. Like all GPCRs, these pheromone mating factor receptors possess the same basic architecture of seven-transmembrane (7TM) domains and share common signaling mechanisms; however, there is no significant sequence similarity either between Ste2 and Ste3, or between these two receptors and the other 7TM GPCRs. Thus, STE2 and STE3 represent phylogenetically distinct groups. : Pssm-ID: 320097 Cd Length: 259 Bit Score: 252.42 E-value: 1.84e-83
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| Name | Accession | Description | Interval | E-value | |||||
| 7tmD_STE3 | cd14966 | fungal a-factor pheromone receptor STE3, member of the class D family of seven-transmembrane G ... |
8-245 | 1.84e-83 | |||||
fungal a-factor pheromone receptor STE3, member of the class D family of seven-transmembrane G protein-coupled receptors; This subfamily represents the a-factor pheromone receptor encoded by the STE3 gene, which is required for pheromone sensing and mating in haploid cells of the yeast Saccharomyces cerevisiae. The STE3-encoded seven-transmembrane domain receptor is a member of the class D GPCRs. Class D receptors are composed of two major subfamilies: Ste2 and Ste3. These two GPCRs (Ste2 and Ste3) sense the polypeptide mating pheromones, alpha-factor and a-factor, which activate a G protein-coupled receptors on the surface of the opposite yeast-mating haploid-types (MATa and MAT-alpha), respectively. Activation of these receptors by pheromones leads to activation of the mitogen-activated protein kinase (MAPK) signal transduction cascades, G1 cell cycle arrest, and polarized cell growth in the direction of the partner cell (a process called shmooing), which ultimately induces cell-cell fusion and the formation of a diploid zygote. Like all GPCRs, these pheromone mating factor receptors possess the same basic architecture of seven-transmembrane (7TM) domains and share common signaling mechanisms; however, there is no significant sequence similarity either between Ste2 and Ste3, or between these two receptors and the other 7TM GPCRs. Thus, STE2 and STE3 represent phylogenetically distinct groups. Pssm-ID: 320097 Cd Length: 259 Bit Score: 252.42 E-value: 1.84e-83
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| STE3 | pfam02076 | Pheromone A receptor; |
10-266 | 1.82e-79 | |||||
Pheromone A receptor; Pssm-ID: 460437 Cd Length: 292 Bit Score: 243.23 E-value: 1.82e-79
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| Name | Accession | Description | Interval | E-value | |||||
| 7tmD_STE3 | cd14966 | fungal a-factor pheromone receptor STE3, member of the class D family of seven-transmembrane G ... |
8-245 | 1.84e-83 | |||||
fungal a-factor pheromone receptor STE3, member of the class D family of seven-transmembrane G protein-coupled receptors; This subfamily represents the a-factor pheromone receptor encoded by the STE3 gene, which is required for pheromone sensing and mating in haploid cells of the yeast Saccharomyces cerevisiae. The STE3-encoded seven-transmembrane domain receptor is a member of the class D GPCRs. Class D receptors are composed of two major subfamilies: Ste2 and Ste3. These two GPCRs (Ste2 and Ste3) sense the polypeptide mating pheromones, alpha-factor and a-factor, which activate a G protein-coupled receptors on the surface of the opposite yeast-mating haploid-types (MATa and MAT-alpha), respectively. Activation of these receptors by pheromones leads to activation of the mitogen-activated protein kinase (MAPK) signal transduction cascades, G1 cell cycle arrest, and polarized cell growth in the direction of the partner cell (a process called shmooing), which ultimately induces cell-cell fusion and the formation of a diploid zygote. Like all GPCRs, these pheromone mating factor receptors possess the same basic architecture of seven-transmembrane (7TM) domains and share common signaling mechanisms; however, there is no significant sequence similarity either between Ste2 and Ste3, or between these two receptors and the other 7TM GPCRs. Thus, STE2 and STE3 represent phylogenetically distinct groups. Pssm-ID: 320097 Cd Length: 259 Bit Score: 252.42 E-value: 1.84e-83
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| STE3 | pfam02076 | Pheromone A receptor; |
10-266 | 1.82e-79 | |||||
Pheromone A receptor; Pssm-ID: 460437 Cd Length: 292 Bit Score: 243.23 E-value: 1.82e-79
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