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Conserved domains on  [gi|1561507034|gb|QAT79822|]
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RepR [Cloning vector pDW12]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PriCT_1 super family cl07362
Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of ...
 266-329 4.34e-08

Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of primases.


The actual alignment was detected with superfamily member pfam08708:

Pssm-ID: 447340  Cd Length: 64  Bit Score: 49.99  E-value: 4.34e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1561507034 266 VSRGDGMLGRNNTLLTLCLAGYSSGWTERDAYDYADQWNSGQREPLSDREVQRIVHSAFSGKYQ 329
Cdd:pfam08708   1 TLGPVASGGRNNALFRLAGALARRGIDRESVLALLHALNSNLEPPLDESEVEKTVKSVYRYVYA 64
HTH_ARSR super family cl46857
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 394-449 8.61e-04

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


The actual alignment was detected with superfamily member pfam02082:

Pssm-ID: 481197 [Multi-domain]  Cd Length: 131  Bit Score: 39.46  E-value: 8.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1561507034 394 QITTRELRAQLGISSQMLTRVLHYVAELNLLKVVRklGRNGGLSLA------TLRMVGRTVQ 449
Cdd:pfam02082  23 PVTSEEIAERQNISPVYLEKILAKLRKAGLVESVR--GAGGGYRLArppeeiTLLDVVRAVE 82
 
Name Accession Description Interval E-value
PriCT_1 pfam08708
Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of ...
 266-329 4.34e-08

Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of primases.


Pssm-ID: 430166  Cd Length: 64  Bit Score: 49.99  E-value: 4.34e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1561507034 266 VSRGDGMLGRNNTLLTLCLAGYSSGWTERDAYDYADQWNSGQREPLSDREVQRIVHSAFSGKYQ 329
Cdd:pfam08708   1 TLGPVASGGRNNALFRLAGALARRGIDRESVLALLHALNSNLEPPLDESEVEKTVKSVYRYVYA 64
Rrf2 pfam02082
Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur ...
 394-449 8.61e-04

Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 396591 [Multi-domain]  Cd Length: 131  Bit Score: 39.46  E-value: 8.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1561507034 394 QITTRELRAQLGISSQMLTRVLHYVAELNLLKVVRklGRNGGLSLA------TLRMVGRTVQ 449
Cdd:pfam02082  23 PVTSEEIAERQNISPVYLEKILAKLRKAGLVESVR--GAGGGYRLArppeeiTLLDVVRAVE 82
PriCT_1 smart00942
Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of ...
 274-325 1.15e-03

Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of primases.


Pssm-ID: 214926  Cd Length: 66  Bit Score: 37.31  E-value: 1.15e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1561507034  274 GRNNTLLTL-CLAGYSSGWTERDAYDYADQWNSG-QREPLSDREVQRIVHSAFS 325
Cdd:smart00942   9 NRNNTLFRLaGRLLRRGYVDEEEAYALLLAANSAnCNPPLPERELEKTAESAYR 62
 
Name Accession Description Interval E-value
PriCT_1 pfam08708
Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of ...
 266-329 4.34e-08

Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of primases.


Pssm-ID: 430166  Cd Length: 64  Bit Score: 49.99  E-value: 4.34e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1561507034 266 VSRGDGMLGRNNTLLTLCLAGYSSGWTERDAYDYADQWNSGQREPLSDREVQRIVHSAFSGKYQ 329
Cdd:pfam08708   1 TLGPVASGGRNNALFRLAGALARRGIDRESVLALLHALNSNLEPPLDESEVEKTVKSVYRYVYA 64
Rrf2 pfam02082
Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur ...
 394-449 8.61e-04

Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 396591 [Multi-domain]  Cd Length: 131  Bit Score: 39.46  E-value: 8.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1561507034 394 QITTRELRAQLGISSQMLTRVLHYVAELNLLKVVRklGRNGGLSLA------TLRMVGRTVQ 449
Cdd:pfam02082  23 PVTSEEIAERQNISPVYLEKILAKLRKAGLVESVR--GAGGGYRLArppeeiTLLDVVRAVE 82
PriCT_1 smart00942
Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of ...
 274-325 1.15e-03

Primase C terminal 1 (PriCT-1); This alpha helical domain is found at the C terminal of primases.


Pssm-ID: 214926  Cd Length: 66  Bit Score: 37.31  E-value: 1.15e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1561507034  274 GRNNTLLTL-CLAGYSSGWTERDAYDYADQWNSG-QREPLSDREVQRIVHSAFS 325
Cdd:smart00942   9 NRNNTLFRLaGRLLRRGYVDEEEAYALLLAANSAnCNPPLPERELEKTAESAYR 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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