|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP1A |
NF038272 |
streptococcal penicillin-binding protein PBP1A; PBP1a is a bifunctional enzyme of cell wall ... |
27-652 |
0e+00 |
|
streptococcal penicillin-binding protein PBP1A; PBP1a is a bifunctional enzyme of cell wall biosynthesis, performing both polymerization of GlcNAc-MurNAc chains (glycosyltransfer, GT) and peptide cross-linking (transpeptidation, TP).
Pssm-ID: 439572 [Multi-domain] Cd Length: 657 Bit Score: 639.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 27 KRYAKYTILTLATLGVVGALGGAGVFAYYASSAPKITNSALVGTSQTQLLDADGNVFYTTGS-KREMAKQSEIPKEMRMA 105
Cdd:NF038272 5 LKILKYLAIALLSLFILAIVIGGLLFAYYVSSAPKLSESKLVATTSSKIYDSNNNLIADLGSeKRENVTADEIPTDLVNA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 106 VVSIEDRRFYKHHGVDPRRILGAAFANFTGSSLglQGGSTLTQQLIKLTAFSTAASDQTIKRKAQEAWLALKLEKEYSKN 185
Cdd:NF038272 85 ITSIEDHRFFNHRGVDVYRILGAALNNLTSSST--QGGSTLDQQLIKLAYFSTSTSDQTLKRKAQEAWLALQLERKYTKQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 186 QILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQ 265
Cdd:NF038272 163 EILTFYINKVYMGNGNYGMQTAAKSYYGKDLKDLSLAQLALLAGMPQAPNQYDPYTNPEAAQERRNLVLSEMYEEKYITK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 266 AQAKKYMALPVTDGLMTTHPSSSTqdeeAKVDDAYIMSTLAEIK-KLGYDVNKDGLTVQTNLNQKVQDRAYAIGNTADYV 344
Cdd:NF038272 243 EQYDQAVATPVTDGLQPLKSTSSY----PAYMDNYLKEVIEQVEeETGYDILTTGMKVYTNVDPDAQKRLWDIYNTDEYV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 345 NWKDDDMQVGMTVTDPNNGKVIAQLGGRNLT--ALQGTNRATNTVRSSGSTAKPIVDYGPAVENLGW-STNHLVLDTPYT 421
Cdd:NF038272 319 YYPDDELQVASTVVDVTNGKVIAQLGSRHQDsnVSFGTNQAVETDRDWGSTMKPITDYAPAIENGVYtSTAASINDSPYN 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 422 YPGTNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFLKKLGIDIPanEMVGSSAIGIN---------V 492
Cdd:NF038272 399 WPGTSTPVYNWDRRYYGNMTIQTAIQQSRNVPAVKALEAVGLDKAKSFLNGLGINYP--EMHYSNAISSNtsssdkkygA 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 493 STEQEAAAYAAFANGGTYYKPQYISKITEQSGVVKDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAkminTNAY----SQ 568
Cdd:NF038272 477 SSEKMAAAYAAFANGGTYYKPQYVNKIVFSDGTTKEFSNKGTRAMKETTAYMMTDMMKTVLTYGTG----TNAAisgvYQ 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 569 AGKTGVVGYED------------GADVPDGAAHDTWFTGFTKSASISVWTGYDRPNEPghylAEGEEQYVALHAYKALMD 636
Cdd:NF038272 553 AGKTGTSNYTDdelakieketglYNSSVGTMAPDENFVGYTPKYSMAVWTGYKNRLTP----IYGDGLKVATDVYRSMMS 628
|
650
....*....|....*.
gi 1561270575 637 YvMSGGDDGSDWTMPD 652
Cdd:NF038272 629 Y-LTEGSGSEDWTMPS 643
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
52-657 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 559.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 52 FAYYASSAPKITNSALVGTSQT-QLLDADGNVFYTTGS-KREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAA 129
Cdd:COG0744 34 VALYVADLPDPEELEDLALPQTsTIYDRDGTLIATLGDeNREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 130 FANFTGSSlGLQGGSTLTQQLIKLTAFSTaasDQTIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAE 209
Cdd:COG0744 114 VANLTAGG-VVQGGSTITQQLVKNLFLSN---ERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQ 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 210 YYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQAQAKKYMALPVTdgLMTTHPSSST 289
Cdd:COG0744 190 YYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLT--LVPPPNGAAA 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 290 QDEEAKVDdaYIMSTLAEikKLGYD-VNKDGLTVQTNLNQKVQDRAYAIGNtADYVNWKDDDMQVGMTVTDPNNGKVIAQ 368
Cdd:COG0744 268 GKYPYFVD--YVRRELEE--LLGEDdLYRGGLKIYTTLDPKLQKAAEKAVK-NVLPEGKPGGLQAALVVVDPKTGEVLAM 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 369 LGGRNLTAlQGTNRATNTVRSSGSTAKPIVdYGPAVENlGWSTNHLVLDTPYTYPGTNIQPNDWDHKFMGSMTMRNALAQ 448
Cdd:COG0744 343 VGGRDYGK-SQFNRATQAKRQPGSTFKPFV-YAAALEQ-GYTPATTVDDEPVTFPGGGWSPKNYDGRYRGPVTLREALAN 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 449 SRNLPAIRTLQEVGYTKSLEFLKKLGIDIPANEmVGSSAIG-INVSTEQEAAAYAAFANGGTYYKPQYISKITEQSG-VV 526
Cdd:COG0744 420 SLNTPAVRLAQEVGLDKVVDTARRLGITSPLDP-NPSLALGtSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGkVL 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 527 KDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAKMINTNAYSQAGKTGVVgyEDgadvpdgaAHDTWFTGFTKSASISVWT 606
Cdd:COG0744 499 YEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTT--ND--------NRDAWFVGYTPQLVTAVWV 568
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1561270575 607 GYDRpNEPGHYLAEGeeqYVALHAYKALMDYVMSGGdDGSDWTMPDTVRQV 657
Cdd:COG0744 569 GNDD-NSPMGYVTGG---SLPAPIWRDFMEAALEGL-PVEDFPKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
89-641 |
2.06e-168 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 496.40 E-value: 2.06e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 89 KREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTGSSlGLQGGSTLTQQLIKLTAFStaaSDQTIKRK 168
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGR-VLEGGSTITQQLAKNLYLT---NERTITRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 169 AQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKA 248
Cdd:TIGR02074 77 IQEALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 249 RRDEVLEAMAQNNVITQAQAKKYMALPVTDGLMtthpsssTQDEEAKVDDAYIMSTLAEI-KKLGYDVNKDGLTVQTNLN 327
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQ-------TKKSEQYKAPYFVDYVIQELeEEYGEELYTGGLKIYTTLD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 328 QKVQDRAYAIGNTADYVNWKDD--DMQVGMTVTDPNNGKVIAQLGGRNLTAlQGTNRATNTVRSSGSTAKPIVdYGPAVE 405
Cdd:TIGR02074 230 LDAQKAAEKVLNTGLRVAGRRDgdDLQAALVAIDPDTGAVRALVGGRDYGK-SQFNRATQAKRQPGSTFKPFV-YAAALE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 406 NlGWSTNHLVLDTPYTYPG-TNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFLKKLGIDIPANeMVG 484
Cdd:TIGR02074 308 K-GLTPATIVNDEPITYNGnGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLD-PVL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 485 SSAIG-INVSTEQEAAAYAAFANGGTYYKPQYISKITEQSG-VVKDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAKMIN 562
Cdd:TIGR02074 386 SLALGtVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGkVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSAR 465
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1561270575 563 TNAYSQAGKTGVVGYedgadvpdgaAHDTWFTGFTKSASISVWTGYDRPNEPGHylaEGEEQYVALHAYKALMDYVMSG 641
Cdd:TIGR02074 466 LPGRPVAGKTGTTQN----------WRDAWFVGYTPYYVTAVWVGYDDKKTLGK---SGTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
79-258 |
4.47e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 262.07 E-value: 4.47e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 79 DGNVFYTTGS-KREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTGSSLGlQGGSTLTQQLIKLTAFS 157
Cdd:pfam00912 1 DGTLLAELGEeNREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIV-QGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 158 TaasDQTIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGY 237
Cdd:pfam00912 80 P---ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRY 156
|
170 180
....*....|....*....|.
gi 1561270575 238 DPYVNPKGAKARRDEVLEAMA 258
Cdd:pfam00912 157 NPLRNPERAKRRRNLVLDRMV 177
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
87-614 |
1.09e-53 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 199.61 E-value: 1.09e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 87 GSKREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTgSSLGLQGGSTLTQQLIKlTAFSTaaSDQTIK 166
Cdd:PRK09506 208 GEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLT-AGRTVQGGSTLTQQLVK-NLFLS--NERSLW 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 167 RKAQEAWLALKLEKEYSKNQILTLYMNKVYMG----NGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVN 242
Cdd:PRK09506 284 RKANEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRN 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 243 PKGAKARRDEVLEAMAQNNVITQAQAKKYMALPV----TDGLMTTHPssstqdeeakvddAYIMSTLAEIK-KLGYDVNK 317
Cdd:PRK09506 364 PKLALERRNLVLRLLQQQQIIDQELYDMLSARPLgvqpKGGVISPQP-------------AFMQMVRQELQaKLGDKVKD 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 318 -DGLTVQTNLNQKVQD---RAYAIGNTADYVNWKDDDMQVGMTVTDPNNGKVIAQLGGRNlTALQGTNRATNTVRSSGST 393
Cdd:PRK09506 431 lSGVKIFTTLDPVSQDaaeKAVEEGIPALKKQRKLSDLETAMVVVDRFSGEVRAMVGGSE-PQFAGYNRAMQARRSIGSL 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 394 AKPIVDYGPAVENLGWSTNHLVLDTPYTYP---GTNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFL 470
Cdd:PRK09506 510 AKPATYLTALSQPDKYRLNTWIADAPISLRqpnGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTW 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 471 KKLGidIPANEM--VGSSAIG-INVSTEQEAAAYAAFANGGTYYKPQYI-SKITEQSGVVKDYKAEGSTAMKSSTAFMLT 546
Cdd:PRK09506 590 IKLG--VPKDQLnpVPAMLLGaLNLTPIEVAQAFQTIASGGNRAPLSALrSVIAEDGKVLYQSFPQAERAVPAQAAYLTL 667
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 547 NMMKSVITDSYAKMINTN--AYSQAGKTGVVgyedgadvpdGAAHDTWFTGFTKSASISVWTGYDRpNEP 614
Cdd:PRK09506 668 YTMQQVVQRGTGRQLGAKypNLHLAGKTGTT----------NDLVDSWFAGIDGKEVTITWVGRDN-NQP 726
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP1A |
NF038272 |
streptococcal penicillin-binding protein PBP1A; PBP1a is a bifunctional enzyme of cell wall ... |
27-652 |
0e+00 |
|
streptococcal penicillin-binding protein PBP1A; PBP1a is a bifunctional enzyme of cell wall biosynthesis, performing both polymerization of GlcNAc-MurNAc chains (glycosyltransfer, GT) and peptide cross-linking (transpeptidation, TP).
Pssm-ID: 439572 [Multi-domain] Cd Length: 657 Bit Score: 639.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 27 KRYAKYTILTLATLGVVGALGGAGVFAYYASSAPKITNSALVGTSQTQLLDADGNVFYTTGS-KREMAKQSEIPKEMRMA 105
Cdd:NF038272 5 LKILKYLAIALLSLFILAIVIGGLLFAYYVSSAPKLSESKLVATTSSKIYDSNNNLIADLGSeKRENVTADEIPTDLVNA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 106 VVSIEDRRFYKHHGVDPRRILGAAFANFTGSSLglQGGSTLTQQLIKLTAFSTAASDQTIKRKAQEAWLALKLEKEYSKN 185
Cdd:NF038272 85 ITSIEDHRFFNHRGVDVYRILGAALNNLTSSST--QGGSTLDQQLIKLAYFSTSTSDQTLKRKAQEAWLALQLERKYTKQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 186 QILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQ 265
Cdd:NF038272 163 EILTFYINKVYMGNGNYGMQTAAKSYYGKDLKDLSLAQLALLAGMPQAPNQYDPYTNPEAAQERRNLVLSEMYEEKYITK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 266 AQAKKYMALPVTDGLMTTHPSSSTqdeeAKVDDAYIMSTLAEIK-KLGYDVNKDGLTVQTNLNQKVQDRAYAIGNTADYV 344
Cdd:NF038272 243 EQYDQAVATPVTDGLQPLKSTSSY----PAYMDNYLKEVIEQVEeETGYDILTTGMKVYTNVDPDAQKRLWDIYNTDEYV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 345 NWKDDDMQVGMTVTDPNNGKVIAQLGGRNLT--ALQGTNRATNTVRSSGSTAKPIVDYGPAVENLGW-STNHLVLDTPYT 421
Cdd:NF038272 319 YYPDDELQVASTVVDVTNGKVIAQLGSRHQDsnVSFGTNQAVETDRDWGSTMKPITDYAPAIENGVYtSTAASINDSPYN 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 422 YPGTNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFLKKLGIDIPanEMVGSSAIGIN---------V 492
Cdd:NF038272 399 WPGTSTPVYNWDRRYYGNMTIQTAIQQSRNVPAVKALEAVGLDKAKSFLNGLGINYP--EMHYSNAISSNtsssdkkygA 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 493 STEQEAAAYAAFANGGTYYKPQYISKITEQSGVVKDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAkminTNAY----SQ 568
Cdd:NF038272 477 SSEKMAAAYAAFANGGTYYKPQYVNKIVFSDGTTKEFSNKGTRAMKETTAYMMTDMMKTVLTYGTG----TNAAisgvYQ 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 569 AGKTGVVGYED------------GADVPDGAAHDTWFTGFTKSASISVWTGYDRPNEPghylAEGEEQYVALHAYKALMD 636
Cdd:NF038272 553 AGKTGTSNYTDdelakieketglYNSSVGTMAPDENFVGYTPKYSMAVWTGYKNRLTP----IYGDGLKVATDVYRSMMS 628
|
650
....*....|....*.
gi 1561270575 637 YvMSGGDDGSDWTMPD 652
Cdd:NF038272 629 Y-LTEGSGSEDWTMPS 643
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
52-657 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 559.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 52 FAYYASSAPKITNSALVGTSQT-QLLDADGNVFYTTGS-KREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAA 129
Cdd:COG0744 34 VALYVADLPDPEELEDLALPQTsTIYDRDGTLIATLGDeNREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 130 FANFTGSSlGLQGGSTLTQQLIKLTAFSTaasDQTIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAE 209
Cdd:COG0744 114 VANLTAGG-VVQGGSTITQQLVKNLFLSN---ERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQ 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 210 YYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQAQAKKYMALPVTdgLMTTHPSSST 289
Cdd:COG0744 190 YYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLT--LVPPPNGAAA 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 290 QDEEAKVDdaYIMSTLAEikKLGYD-VNKDGLTVQTNLNQKVQDRAYAIGNtADYVNWKDDDMQVGMTVTDPNNGKVIAQ 368
Cdd:COG0744 268 GKYPYFVD--YVRRELEE--LLGEDdLYRGGLKIYTTLDPKLQKAAEKAVK-NVLPEGKPGGLQAALVVVDPKTGEVLAM 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 369 LGGRNLTAlQGTNRATNTVRSSGSTAKPIVdYGPAVENlGWSTNHLVLDTPYTYPGTNIQPNDWDHKFMGSMTMRNALAQ 448
Cdd:COG0744 343 VGGRDYGK-SQFNRATQAKRQPGSTFKPFV-YAAALEQ-GYTPATTVDDEPVTFPGGGWSPKNYDGRYRGPVTLREALAN 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 449 SRNLPAIRTLQEVGYTKSLEFLKKLGIDIPANEmVGSSAIG-INVSTEQEAAAYAAFANGGTYYKPQYISKITEQSG-VV 526
Cdd:COG0744 420 SLNTPAVRLAQEVGLDKVVDTARRLGITSPLDP-NPSLALGtSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGkVL 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 527 KDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAKMINTNAYSQAGKTGVVgyEDgadvpdgaAHDTWFTGFTKSASISVWT 606
Cdd:COG0744 499 YEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTT--ND--------NRDAWFVGYTPQLVTAVWV 568
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1561270575 607 GYDRpNEPGHYLAEGeeqYVALHAYKALMDYVMSGGdDGSDWTMPDTVRQV 657
Cdd:COG0744 569 GNDD-NSPMGYVTGG---SLPAPIWRDFMEAALEGL-PVEDFPKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
89-641 |
2.06e-168 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 496.40 E-value: 2.06e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 89 KREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTGSSlGLQGGSTLTQQLIKLTAFStaaSDQTIKRK 168
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGR-VLEGGSTITQQLAKNLYLT---NERTITRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 169 AQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKA 248
Cdd:TIGR02074 77 IQEALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 249 RRDEVLEAMAQNNVITQAQAKKYMALPVTDGLMtthpsssTQDEEAKVDDAYIMSTLAEI-KKLGYDVNKDGLTVQTNLN 327
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQ-------TKKSEQYKAPYFVDYVIQELeEEYGEELYTGGLKIYTTLD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 328 QKVQDRAYAIGNTADYVNWKDD--DMQVGMTVTDPNNGKVIAQLGGRNLTAlQGTNRATNTVRSSGSTAKPIVdYGPAVE 405
Cdd:TIGR02074 230 LDAQKAAEKVLNTGLRVAGRRDgdDLQAALVAIDPDTGAVRALVGGRDYGK-SQFNRATQAKRQPGSTFKPFV-YAAALE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 406 NlGWSTNHLVLDTPYTYPG-TNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFLKKLGIDIPANeMVG 484
Cdd:TIGR02074 308 K-GLTPATIVNDEPITYNGnGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLD-PVL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 485 SSAIG-INVSTEQEAAAYAAFANGGTYYKPQYISKITEQSG-VVKDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAKMIN 562
Cdd:TIGR02074 386 SLALGtVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGkVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSAR 465
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1561270575 563 TNAYSQAGKTGVVGYedgadvpdgaAHDTWFTGFTKSASISVWTGYDRPNEPGHylaEGEEQYVALHAYKALMDYVMSG 641
Cdd:TIGR02074 466 LPGRPVAGKTGTTQN----------WRDAWFVGYTPYYVTAVWVGYDDKKTLGK---SGTGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
73-660 |
3.42e-121 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 382.59 E-value: 3.42e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 73 TQLLDADGNV---FYTTgsKREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANF-TGSSLglQGGSTLTQ 148
Cdd:COG5009 48 SRVYSADGKLiaeFGEE--RRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLrTGRRV--QGGSTITQ 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 149 QLIK---LTafstaaSDQTIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMA 225
Cdd:COG5009 124 QVAKnflLS------PERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAA 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 226 LLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQAQAKKYMALPVtdglmTTHPSSSTQDEEAkvddAYImstl 305
Cdd:COG5009 198 MLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPL-----TARYHGASAEVDA----PYF---- 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 306 AE------IKKLGYD-VNKDGLTVQTNLNQKVQDRAY--------------------------------AIGNTADYVNW 346
Cdd:COG5009 265 AEmvrrelVERYGEDaLYTGGLKVYTTLDPRLQEAAEkalrdgllaydrrhgyrgpeahldlaeedwdeALAEVPDVGDL 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 347 K--------DDDMQVGM----TVT-------------------------------------------------------- 358
Cdd:COG5009 345 RpavvlevdDKSARVGLrdgeTGTlpleglkwarpyindnrrgpapksasdvlkpgdvirvrpvadggwrlrqipevqga 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 359 ----DPNNGKVIAQLGGRNLTALQgTNRATNTVRSSGSTAKPIVdYGPAVENlGWSTNHLVLDTPYTYPGTNIQ----PN 430
Cdd:COG5009 425 lvalDPHTGAVLALVGGFDFEQSK-FNRATQAKRQPGSSFKPFV-YAAALDN-GYTPATIINDAPIVFDDGGGGgvwrPK 501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 431 DWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFLKKLGID--IPANEmvgSSAIG-INVSTEQEAAAYAAFANG 507
Cdd:COG5009 502 NYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYskLPPNL---SLALGsGEVTPLEMARAYAVFANG 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 508 GTYYKPQYISKITEQSGVVkDYKAEGSTA-----------------------MKSSTAFMLTNMMKSVI---TDSYAKMI 561
Cdd:COG5009 579 GYRVEPYLIDRIEDRNGKV-IYRADPARAcedcdaaewdgaeprlpdpaeqvIDPRTAYQMTSMLRGVVqrgTGRRARAL 657
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 562 NTNAysqAGKTGvvgyedgadvpdgaAHDTWFTGFTKSASISVWTGYDRPNEPGHYlaegeEQ--YVALHAYKALMDYVM 639
Cdd:COG5009 658 GRDI---AGKTGtt----------ndSKDAWFVGFTPDLVAGVWVGFDDPRSLGRG-----ETggRAALPIWIDFMKAAL 719
|
730 740
....*....|....*....|.
gi 1561270575 640 SGGDDgSDWTMPDTVRQVTVN 660
Cdd:COG5009 720 KDKPE-KPFPVPEGIVTVRID 739
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
87-637 |
5.13e-85 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 285.08 E-value: 5.13e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 87 GSKREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTgSSLGLQGGSTLTQQLIKLTAFStaaSDQTIK 166
Cdd:TIGR02071 144 GEQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLT-AGRTVQGGSTLTQQLVKNLFLS---NERSLW 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 167 RKAQEAWLALKLEKEYSKNQILTLYMNKVYMG----NGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVN 242
Cdd:TIGR02071 220 RKANEAYMALILDARYSKDRILELYLNEVYLGqsgdDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRN 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 243 PKGAKARRDEVLEAMAQNNVITQAQAKKYMALPV----TDGLMTTHPssstqdeeakvddAYIMSTLAEI-KKLGYDVNK 317
Cdd:TIGR02071 300 PDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLgvqkKGGIISRQP-------------AFLQLVRRELrQKLGDKVKD 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 318 D-GLTVQTNLNQKVQDRA-YAIGNTADYVN--WKDDDMQVGMTVTDPNNGKVIAQLGGRNlTALQGTNRATNTVRSSGST 393
Cdd:TIGR02071 367 LsGLRIFTTLDPVSQSAAeQAVQETIPALKkkKKLPDLEAAMVVTDRFTGEVRAMVGGSD-PQFAGFNRALQARRQIGSL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 394 AKPIVdYGPAVENLG-WSTNHLVLDTPYTYPGTNIQ---PNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEF 469
Cdd:TIGR02071 446 VKPAV-YLTALSQPDkYRLNTWIEDQPLSIKLSNGQvwsPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQT 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 470 LKKLGID---IPANE--MVGSsaigINVSTEQEAAAYAAFANGGtYYKPQYI--SKITEQSGVVKDYKAEGSTAMKSSTA 542
Cdd:TIGR02071 525 WNKLGINkdeIPPVPsmLLGA----INLTPYEVAQLYQTIASGG-NRAPLSAvrSVLDEDGKVLYQSDPQAEQAVPSQAA 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 543 FMLTNMMKSVITDSYAKMINTN--AYSQAGKTGVVgyEDGadvpdgaaHDTWFTGFTKSASISVWTGYDRPNEPGHYLAE 620
Cdd:TIGR02071 600 YLTLYAMQQVVQRGTARSLGADfpSLSLAGKTGTT--NDN--------RDSWFAGIDGKEVTIIWLGRDDNGPTKLTGAS 669
|
570
....*....|....*..
gi 1561270575 621 GeeqyvALHAYKALMDY 637
Cdd:TIGR02071 670 G-----ALQVYARYLSY 681
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
79-258 |
4.47e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 262.07 E-value: 4.47e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 79 DGNVFYTTGS-KREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTGSSLGlQGGSTLTQQLIKLTAFS 157
Cdd:pfam00912 1 DGTLLAELGEeNREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIV-QGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 158 TaasDQTIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGY 237
Cdd:pfam00912 80 P---ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRY 156
|
170 180
....*....|....*....|.
gi 1561270575 238 DPYVNPKGAKARRDEVLEAMA 258
Cdd:pfam00912 157 NPLRNPERAKRRRNLVLDRMV 177
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
73-612 |
1.34e-71 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 249.36 E-value: 1.34e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 73 TQLLDADGNVFYTTGSKREM----AKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTGsslG--LQGGSTL 146
Cdd:COG4953 44 TVVLDRDGTLLRAFLAADGQwrlpVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRS---GriVSGGSTL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 147 TQQLIKLtafstaaSDQ---TIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQ 223
Cdd:COG4953 121 TMQVARL-------LEPrprTLSGKLRQILRALQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAE 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 224 MALLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQAQAKKYMALPV--------------TDGLMTTHPssst 289
Cdd:COG4953 194 AALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVIDAEEAALALLEPVparrrplpqlaphlARRLLRQLP---- 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 290 qdeeakvDDAYIMSTLaeikklgyDVNkdgltVQTNLNQKVQDRAYAIGNtadyvnwkDDDMQVGMTVTDPNNGKVIAQL 369
Cdd:COG4953 270 -------GGTRIRTTL--------DAG-----LQRRLERLVRRYVRRLKQ--------NGIHNAAVLVVDNRTGEVLAYV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 370 GGRNLT--ALQGTNRATNTVRSSGSTAKPIVdYGPAVENLGWSTNHLVLDTPytypgTNI---QPNDWDHKFMGSMTMRN 444
Cdd:COG4953 322 GSADFFdaSRQGQVDMVRALRSPGSTLKPFL-YGLALDQGLIHPETLLADVP-----TSFggyRPENFDGTFQGPVSARE 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 445 ALAQSRNLPAIRTLQEVGYTKSLEFLKKLGID--IPANEMVGSSAI--GINVSTEQEAAAYAAFANGGTYYKPQYISkit 520
Cdd:COG4953 396 ALARSLNIPAVRLLEALGPARFYARLRRAGLRllLPPAEHYGLSLIlgGAEVTLEELVGLYAALARGGEARPLRLLA--- 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 521 eqsgvvKDYKAEGSTAMKSSTAFMLTNMMKSVITDsyAKMINTNAYSQAG----KTGV-VGYedgadvpdgaaHDTWFTG 595
Cdd:COG4953 473 ------GEPASPGRRLLSPGAAWLVRDILSDVPRP--DGAFGWRALDSPPpiawKTGTsYGF-----------RDAWAVG 533
|
570
....*....|....*..
gi 1561270575 596 FTKSASISVWTGydRPN 612
Cdd:COG4953 534 FTGRYTVGVWVG--NPD 548
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
87-614 |
1.09e-53 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 199.61 E-value: 1.09e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 87 GSKREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTgSSLGLQGGSTLTQQLIKlTAFSTaaSDQTIK 166
Cdd:PRK09506 208 GEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLT-AGRTVQGGSTLTQQLVK-NLFLS--NERSLW 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 167 RKAQEAWLALKLEKEYSKNQILTLYMNKVYMG----NGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVN 242
Cdd:PRK09506 284 RKANEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRN 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 243 PKGAKARRDEVLEAMAQNNVITQAQAKKYMALPV----TDGLMTTHPssstqdeeakvddAYIMSTLAEIK-KLGYDVNK 317
Cdd:PRK09506 364 PKLALERRNLVLRLLQQQQIIDQELYDMLSARPLgvqpKGGVISPQP-------------AFMQMVRQELQaKLGDKVKD 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 318 -DGLTVQTNLNQKVQD---RAYAIGNTADYVNWKDDDMQVGMTVTDPNNGKVIAQLGGRNlTALQGTNRATNTVRSSGST 393
Cdd:PRK09506 431 lSGVKIFTTLDPVSQDaaeKAVEEGIPALKKQRKLSDLETAMVVVDRFSGEVRAMVGGSE-PQFAGYNRAMQARRSIGSL 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 394 AKPIVDYGPAVENLGWSTNHLVLDTPYTYP---GTNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFL 470
Cdd:PRK09506 510 AKPATYLTALSQPDKYRLNTWIADAPISLRqpnGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTW 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 471 KKLGidIPANEM--VGSSAIG-INVSTEQEAAAYAAFANGGTYYKPQYI-SKITEQSGVVKDYKAEGSTAMKSSTAFMLT 546
Cdd:PRK09506 590 IKLG--VPKDQLnpVPAMLLGaLNLTPIEVAQAFQTIASGGNRAPLSALrSVIAEDGKVLYQSFPQAERAVPAQAAYLTL 667
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 547 NMMKSVITDSYAKMINTN--AYSQAGKTGVVgyedgadvpdGAAHDTWFTGFTKSASISVWTGYDRpNEP 614
Cdd:PRK09506 668 YTMQQVVQRGTGRQLGAKypNLHLAGKTGTT----------NDLVDSWFAGIDGKEVTITWVGRDN-NQP 726
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
87-637 |
1.98e-53 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 198.15 E-value: 1.98e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 87 GSKREMAKQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFANFTgSSLGLQGGSTLTQQLIKLTAFSTAASdqtIK 166
Cdd:PRK14850 154 GKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLM-SGHTIQGGSTLTQQLVKNLFLTNTRS---LW 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 167 RKAQEAWLALKLEKEYSKNQILTLYMNKVYMG-NG---VYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVN 242
Cdd:PRK14850 230 RKINEIYMALILDRFYSKDRILELYLNEVYLGqDGneqIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTN 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 243 PKGAKARRDEVLEAMAQNNVITQAQAKKYMALPVT----DGLMTTHPssstqdeeakvddAYIMSTLAEI-KKLGYDV-N 316
Cdd:PRK14850 310 PNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNvqskGNIISSHP-------------AFIQLVCEEFhKKIHYPFkN 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 317 KDGLTVQTNLN---QKVQDRAYAIGNTADYVNWKDDDMQVGMTVTDPNNGKVIAQLGGRNlTALQGTNRATNTVRSSGST 393
Cdd:PRK14850 377 FSGTKIFTTLDyisQNAAEQAVKIGIPILKRKKRLKDLEVAMVIIDRFSGEVRALIGSSK-PEFNGYNRALKARRSIGSL 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 394 AKPIVDYGPAVENLGWSTNHLVLDTPYTYPGTNIQ---PNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFL 470
Cdd:PRK14850 456 SKPITYLTALSQPEKYHLNTWISDTPISIKLDNGQywtPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSW 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 471 KKLGIDIPANEMVGSSAIG-INVSTEQEAAAYAAFANGGTYYKPQYISKITEQSGVVKDYKAEGSTAMKSSTAFMLT-NM 548
Cdd:PRK14850 536 ILLGISSNYITPLPSISLGaINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTlYA 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 549 MKSVITDSYAKMINT--NAYSQAGKTGVVgyedgadvpdGAAHDTWFTGFTKSASISVWTGYDRPNEPGHYLAEGeeqyv 626
Cdd:PRK14850 616 MQQVVKSGTAKSLGTifKEFSLAGKTGTT----------NNLVDSWFVGIDGKQVVITWIGRDNNHTTKLYGSSG----- 680
|
570
....*....|.
gi 1561270575 627 ALHAYKALMDY 637
Cdd:PRK14850 681 AMKIYKRYLQY 691
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
74-526 |
2.30e-49 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 187.26 E-value: 2.30e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 74 QLLDADGNVFYTTGSKREMA-KQSEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAA-FANFTGSSLglQGGSTLTQQLI 151
Cdd:PRK11636 49 QVYSADGELIAQYGEKRRIPlTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAAsVALFSGHAS--QGASTITQQLA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 152 KLTAFStaaSDQTIKRKAQEAWLALKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLP 231
Cdd:PRK11636 127 RNFFLS---PERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLP 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 232 QSPSGYDPYVNPKGAKARRDEVLEAMAQNNVITQAQ---------------------------------AKKYMALPVTD 278
Cdd:PRK11636 204 KAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQydqarsepivanyhapeiafsapylsemvrqemYNRYGENAYED 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 279 GL-----MTTHPSSSTQDE-------------------------EAKVDDAYIMSTLAEIKKLG-------YDVN----- 316
Cdd:PRK11636 284 GYrvyttITRKVQQAAQQAvrnnvldydmrhgyrgpanvlwkvgESAWDNKKITDTLKALPTYGpllpavvTSANpqeat 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 317 ---KDGLTVQTNLNQKVQDRAY----AIGNTADYVN---------W----KDD-------DMQVGMTVTDPNNGKVIAQL 369
Cdd:PRK11636 364 amlADGSSVALPMEGVRWARPYrsdtQQGPTPRKVTdvvqtgqqiWvrqvDDAwwlaqvpDVNSALVSINPQNGAVMALV 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 370 GGRNLTaLQGTNRATNTVRSSGSTAKPIVdYGPAVENlGWSTNHLVLDTPYTY----PGTNIQPNDWDHKFMGSMTMRNA 445
Cdd:PRK11636 444 GGFDFN-QSKFNRATQALRQVGSNIKPFL-YTAAMDK-GLTLASMLNDVPISRwdagAGSDWRPKNSPPQYAGPIRLRQG 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 446 LAQSRNLPAIRTLQEVGYTKSLEFLKKLGidIPANEMVG--SSAIGINVSTE-QEAAAYAAFANGGTYYKPQYISKITEQ 522
Cdd:PRK11636 521 LGQSKNVVMVRAMRAMGVDYAAEYLQRFG--FPAQNIVHteSLALGSASFTPmQVARGYAVMANGGFLVDPYFISKIEND 598
|
....
gi 1561270575 523 SGVV 526
Cdd:PRK11636 599 QGGV 602
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
105-462 |
1.13e-36 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 147.92 E-value: 1.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 105 AVVSIEDRRFYKHHGVDPRRILGAAFANFTGSSLgLQGGSTLTQQLIKLTAfstaASDQTIKRKAQEAWLALKLEKEYSK 184
Cdd:PRK11240 77 ALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRV-ISGGSTLTMQVARLLD----PHPRTFGGKIRQLWRALQLEWHLSK 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 185 NQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKARRDEVLEAMAQNNVIT 264
Cdd:PRK11240 152 REILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVWS 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 265 QAQAKKYMALPVtdglmTTHPSSSTQdeeakvddayIMSTLAEIKKLGYDVNKDGLTVQTNLNQKVQDRAyaigntadyV 344
Cdd:PRK11240 232 AEQVKESREEPV-----WLAPRQMPQ----------LAPLFARMMLGKSKSDKIVTTLDAGLQRRLEDLA---------L 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 345 NWKD---DDMQVGMTVTDPNNGKVIAQLGGRNLT--ALQGTNRATNTVRSSGSTAKPIVdYGPAVENLGWSTNHLVLDTP 419
Cdd:PRK11240 288 NWKGrlpPRSSLAMIVVDHTDMAVRGWVGSVDLNddSRFGHVDMVNAIRSPGSVLKPFV-YGLALDDGLIHPASLLQDVP 366
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1561270575 420 YTYpgTNIQPNDWDHKFMGSMTMRNALAQSRNLPAIRTLQEVG 462
Cdd:PRK11240 367 RRT--GDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYG 407
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
96-273 |
1.40e-33 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 128.77 E-value: 1.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 96 SEIPKEMRMAVVSIEDRRFYKHHGVDPRRILGAAFAnfTGSSLGLQGGSTLTQQLIKLTAFStaaSDQTIKRKAQEAWLA 175
Cdd:PRK13481 51 DNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFS--TISDRDVQGGSTITQQVVKNYFYD---NERSFTRKVKELFVA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 176 LKLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFG----KDLKNLSTP---QMALLAGLPQSPSGYDPYVNPKGAKA 248
Cdd:PRK13481 126 HRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGttvnKNSTTMSHItvlQSAILASKVNAPSVYNINDMSENFTQ 205
|
170 180
....*....|....*....|....*
gi 1561270575 249 RRDEVLEAMAQNNVITQAQAKKYMA 273
Cdd:PRK13481 206 RVSTNLEKMKQQNYINETQYQQAMS 230
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
97-259 |
5.11e-31 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 121.41 E-value: 5.11e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 97 EIPKEMRMAVVSIEDRRFYKHHGVDPRRILgAAFANFTGSSLGLQGGSTLTQQLIKLTAFStaaSDQTIKRKAQEAWLAL 176
Cdd:TIGR02070 62 QISPNLKRAVIASEDAKFVEHHGFDWEAIQ-DALEKNEKSGKVVRGGSTISQQLAKNLFLW---SGRSYLRKGLEAWATW 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 177 KLEKEYSKNQILTLYMNKVYMGNGVYGMKTAAEYYFGKDLKNLSTPQMALLAGLPQSPSGYDPYVNPKGAKARRDEVLEA 256
Cdd:TIGR02070 138 MLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQ 217
|
...
gi 1561270575 257 MAQ 259
Cdd:TIGR02070 218 MGY 220
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
356-599 |
7.39e-24 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 102.49 E-value: 7.39e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 356 TVTDPNNGKVIAQLGGR----NLTALQGTNRATNTVRSSGSTAKPIVdYGPAVENLGWSTNHLVLDTPYTYpGTNIQPND 431
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKPsydpNGFIGPLRNRAVTSRYEPGSTFKPFT-ALAALDNGVLKPDETIFDWPGKQ-QGGKSIGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 432 WDHKFMGSMTMRNALAQSRNLPAIRTLQEVGYTKSLEFLKKLGIDIP-----ANEMVG------------SSAIGINVST 494
Cdd:pfam00905 82 WNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKtgiglPGENAGyltpywlegataSFGIGLTITP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 495 EQEAAAYAAFANGGTYYKPQYISKITEQsgvvKDYKAEGSTAMKSSTAFMLTNMMKSVITDSYAKMINTNA-YSQAGKTG 573
Cdd:pfam00905 162 LQQAQAYAAIANGGKLVPPHLVKSIEDK----VDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVPgYKVAGKTG 237
|
250 260
....*....|....*....|....*...
gi 1561270575 574 --VVGYEDGADVPDGAAHdTWFTGFTKS 599
Cdd:pfam00905 238 taQVAGPKGGGYYDGAQI-GWFVGYAPA 264
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
307-596 |
2.53e-22 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 101.82 E-value: 2.53e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 307 EIKKLGYDVN-KDGLTVQTNLNQKVQDRAY-AIGNTADYVNWKdddmQVGMTVTDPNNGKVIA----------QLGGRNL 374
Cdd:COG0768 205 VIRDLGEEKPpVPGKDLVLTIDSDLQKIAEeALKKAVEEYKAK----SGAVVVMDPKTGEILAmasypsfdpnLFVGGPD 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 375 TALqgTNRATNTVRSSGSTAKPIVDYGpAVENLGWSTNHLVLDTP-YTYPGTNIqpNDWDHKFMGSMTMRNALAQSRNLP 453
Cdd:COG0768 281 EPL--RNRAVQGTYEPGSTFKPFTAAA-ALEEGVITPDTTFDCPGyYRVGGRTI--RDWDRGGHGTLTLTEALAKSSNVG 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 454 AIRTLQEVG------YTKSLEFLKKLGIDIPaNEMVG--------------SSAIG--INVSTEQEAAAYAAFANGGTYY 511
Cdd:COG0768 356 FYKLALRLGidklydYLKKFGLGQKTGIDLP-GEASGllpspkrwypgetaTMSIGqgLSVTPLQLAQAYAAIANGGVLV 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 512 KPQYISKITEQSG-VVKDYKAEGSTAMKSSTAFMLTNMMKSVITDSY--AKMINTNAYSQAGKTG---VVGYEDGADVPD 585
Cdd:COG0768 435 KPHLVKEIVDPDGeVVKEEPEVLRRVISPETAETVREGMEGVVNEPGgtARRAAIPGYRVAGKTGtaqVVDIGNGGYYKG 514
|
330
....*....|.
gi 1561270575 586 GaaHDTWFTGF 596
Cdd:COG0768 515 R--HIASFVGF 523
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
319-596 |
8.42e-09 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 59.07 E-value: 8.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 319 GLTVQTNLNQKVQDRAY-AIGNTADYVnwkdddmqVgmtVTDPNNGKVIA--------------QLGGRNLTALQG---- 379
Cdd:TIGR03423 225 GKDLVLTIDARLQQAAEkALGGRRGAV--------V---VMDPRTGEILAmvstpsfdpnlfvdGISSKDYKALLNdpdr 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 380 --TNRATNTVRSSGSTAKPIVdYGPAVENlGWSTNHLVLDTP--YTYPGTNIqpNDWDHKFMGSMTMRNALAQSRNLPAI 455
Cdd:TIGR03423 294 plLNRAIQGVYPPGSTFKPVV-ALAALEE-GVITPETRIYCPgyFQLGGRRF--RCWKRGGHGRVDLRKAIEESCDVYFY 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 456 RTLQEVGYTKSLEFLKKLG------IDIPaNEMVG----------------------SSAIG---INVSTEQEAAAYAAF 504
Cdd:TIGR03423 370 QLALRLGIDKIAEYAKRFGfgqktgIDLP-GEKSGlvpsrewkrkrfgqpwypgdtlNVSIGqgyVLVTPLQLAVATAAL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1561270575 505 ANGGTYYKPQYISKITEQ-SGVVKDYKAE--GSTAMKSSTAFMLTNMMKSVITDSY---AKMINTNAYSQAGKTG---VV 575
Cdd:TIGR03423 449 ANGGKLYKPHLVKSIEDPdGGVVRRTEPEvlRPLPISPENLDVVREGMRDVVNGPGgtaRRARLGLPYKMAGKTGtaqVV 528
|
330 340
....*....|....*....|....*.
gi 1561270575 576 GYEDGA--DVPDGAAHDT---WFTGF 596
Cdd:TIGR03423 529 SLKQGEkyDAEQIPERLRdhaLFVAF 554
|
|
| |
