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Conserved domains on  [gi|156097100|ref|XP_001614583|]
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signal peptidase, putative [Plasmodium vivax]

Protein Classification

signal peptidase complex subunit 3 family protein( domain architecture ID 10015218)

signal peptidase complex subunit 3 (SPCS3) family protein similar to SPCS3, a component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00116 PTZ00116
signal peptidase; Provisional
 1-185 1.39e-110

signal peptidase; Provisional


:

Pssm-ID: 173408  Cd Length: 185  Bit Score: 313.14  E-value: 1.39e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100   1 MDNVLNRLNVLSYSMALCFFTLCLFNYGTSFYLFDEKEMSTSIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNWNL 80
Cdd:PTZ00116   1 MDNVLNRLNVLSYSMALCFLILCLFNYGTSFYLFDEKEMSTNIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNWNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100  81 KQLFLYVLVTYETPEKVKNEVIIQDYIITNKKMAKKTHKNFFTKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYEGA 160
Cdd:PTZ00116  81 KQLFLYVLVTYETPEKVKNEVIIQDYIITNKKQAKKTYKNFITKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYEGA 160

                        170       180
                 ....*....|....*....|....*
gi 156097100 161 KISYKLPAEYFDNLSANYPLYYPDK 185
Cdd:PTZ00116 161 KISYKLPAEYFDNLPSNYPLYYPDK 185
 
Name Accession Description Interval E-value
PTZ00116 PTZ00116
signal peptidase; Provisional
 1-185 1.39e-110

signal peptidase; Provisional


Pssm-ID: 173408  Cd Length: 185  Bit Score: 313.14  E-value: 1.39e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100   1 MDNVLNRLNVLSYSMALCFFTLCLFNYGTSFYLFDEKEMSTSIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNWNL 80
Cdd:PTZ00116   1 MDNVLNRLNVLSYSMALCFLILCLFNYGTSFYLFDEKEMSTNIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNWNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100  81 KQLFLYVLVTYETPEKVKNEVIIQDYIITNKKMAKKTHKNFFTKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYEGA 160
Cdd:PTZ00116  81 KQLFLYVLVTYETPEKVKNEVIIQDYIITNKKQAKKTYKNFITKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYEGA 160

                        170       180
                 ....*....|....*....|....*
gi 156097100 161 KISYKLPAEYFDNLSANYPLYYPDK 185
Cdd:PTZ00116 161 KISYKLPAEYFDNLPSNYPLYYPDK 185
SPC22 pfam04573
Signal peptidase subunit; Translocation of polypeptide chains across the endoplasmic reticulum ...
 1-169 7.83e-55

Signal peptidase subunit; Translocation of polypeptide chains across the endoplasmic reticulum membrane is triggered by signal sequences. During translocation of the nascent chain through the membrane, the signal sequence of most secretory and membrane proteins is cleaved off. Cleavage occurs by the signal peptidase complex (SPC) which consists of four subunits in yeast and five in mammals. This family is common to yeast and mammals.


Pssm-ID: 461357  Cd Length: 172  Bit Score: 171.21  E-value: 7.83e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100    1 MDNVLNRLNVLSYSMALCFFTLCLFNYGTSFY--LFDEKEMSTSIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNW 78
Cdd:pfam04573   1 MHSLLQRLNAVSAFALTVLAVLCALIALSSLFqdTSSISNIVPSVKVKNSRYYGSVRGKPKDNAKITFDLDADLSPLFNW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100   79 NLKQLFLYVLVTYETPEKVKNEVIIQDYIITNKKMAKKTHKNFFTKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYE 158
Cdd:pfam04573  81 NTKQLFVYLTAEYETKKNSVNQVVIWDKIIRSKEDAKLNLKNAKSKYSFWDDGNSLRGRNVTLTLHWNVMPWVGLLPYGE 160

                         170
                  ....*....|..
gi 156097100  159 GA-KISYKLPAE 169
Cdd:pfam04573 161 TAgSSSFTFPDE 172
 
Name Accession Description Interval E-value
PTZ00116 PTZ00116
signal peptidase; Provisional
 1-185 1.39e-110

signal peptidase; Provisional


Pssm-ID: 173408  Cd Length: 185  Bit Score: 313.14  E-value: 1.39e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100   1 MDNVLNRLNVLSYSMALCFFTLCLFNYGTSFYLFDEKEMSTSIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNWNL 80
Cdd:PTZ00116   1 MDNVLNRLNVLSYSMALCFLILCLFNYGTSFYLFDEKEMSTNIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNWNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100  81 KQLFLYVLVTYETPEKVKNEVIIQDYIITNKKMAKKTHKNFFTKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYEGA 160
Cdd:PTZ00116  81 KQLFLYVLVTYETPEKVKNEVIIQDYIITNKKQAKKTYKNFITKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYEGA 160

                        170       180
                 ....*....|....*....|....*
gi 156097100 161 KISYKLPAEYFDNLSANYPLYYPDK 185
Cdd:PTZ00116 161 KISYKLPAEYFDNLPSNYPLYYPDK 185
SPC22 pfam04573
Signal peptidase subunit; Translocation of polypeptide chains across the endoplasmic reticulum ...
 1-169 7.83e-55

Signal peptidase subunit; Translocation of polypeptide chains across the endoplasmic reticulum membrane is triggered by signal sequences. During translocation of the nascent chain through the membrane, the signal sequence of most secretory and membrane proteins is cleaved off. Cleavage occurs by the signal peptidase complex (SPC) which consists of four subunits in yeast and five in mammals. This family is common to yeast and mammals.


Pssm-ID: 461357  Cd Length: 172  Bit Score: 171.21  E-value: 7.83e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100    1 MDNVLNRLNVLSYSMALCFFTLCLFNYGTSFY--LFDEKEMSTSIKVKSVKRLVYNRHIKGDEAVLSLDLSYDMSKAFNW 78
Cdd:pfam04573   1 MHSLLQRLNAVSAFALTVLAVLCALIALSSLFqdTSSISNIVPSVKVKNSRYYGSVRGKPKDNAKITFDLDADLSPLFNW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156097100   79 NLKQLFLYVLVTYETPEKVKNEVIIQDYIITNKKMAKKTHKNFFTKYSLKDYNNGLRNNNINLQVCYKYMPIVGLSRSYE 158
Cdd:pfam04573  81 NTKQLFVYLTAEYETKKNSVNQVVIWDKIIRSKEDAKLNLKNAKSKYSFWDDGNSLRGRNVTLTLHWNVMPWVGLLPYGE 160

                         170
                  ....*....|..
gi 156097100  159 GA-KISYKLPAE 169
Cdd:pfam04573 161 TAgSSSFTFPDE 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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