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Conserved domains on  [gi|1539640469|emb|VED00154|]
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Asp/Glu/hydantoin racemase [Klebsiella variicola]

Protein Classification

aspartate/glutamate racemase family protein( domain architecture ID 10008322)

aspartate/glutamate racemase family protein similar to Agrobacterium fabrum hydantoin racemase, a key enzyme for the production of optically pure D- and L-amino acids, valuable intermediates for the synthesis of antibiotics, sweeteners, pesticides, pharmaceuticals and biologically active peptides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Dcg1 COG4126
Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];
2-107 4.81e-43

Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];


:

Pssm-ID: 443302  Cd Length: 237  Bit Score: 142.66  E-value: 4.81e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539640469   2 INPNTSLAMTETIGAAARAVAAPGTEILAVCPRAGVPSIEGHFDEAIAAVGVLEQIKAGREQGVDGHVIACFGDPGLLAA 81
Cdd:COG4126     7 INPNTSAAMTERIAAAARAVAAPGTEIEAVTAAFGPASIESRYDEALAAPGVLEAAARAEAEGADAVVIACFGDPGLEAA 86

                          90       100
                  ....*....|....*....|....*.
gi 1539640469  82 RELAQGPVIGIAEAAMHMATMVATRF 107
Cdd:COG4126    87 RELVDIPVVGIAEAAMHAAALLGRRF 112
 
Name Accession Description Interval E-value
Dcg1 COG4126
Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];
2-107 4.81e-43

Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];


Pssm-ID: 443302  Cd Length: 237  Bit Score: 142.66  E-value: 4.81e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539640469   2 INPNTSLAMTETIGAAARAVAAPGTEILAVCPRAGVPSIEGHFDEAIAAVGVLEQIKAGREQGVDGHVIACFGDPGLLAA 81
Cdd:COG4126     7 INPNTSAAMTERIAAAARAVAAPGTEIEAVTAAFGPASIESRYDEALAAPGVLEAAARAEAEGADAVVIACFGDPGLEAA 86

                          90       100
                  ....*....|....*....|....*.
gi 1539640469  82 RELAQGPVIGIAEAAMHMATMVATRF 107
Cdd:COG4126    87 RELVDIPVVGIAEAAMHAAALLGRRF 112
Asp_Glu_race pfam01177
Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2. ...
 1-107 2.52e-26

Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2.1.1, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase EC:4.1.1.76.


Pssm-ID: 426101  Cd Length: 210  Bit Score: 98.88  E-value: 2.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539640469   1 MINPNTSLAMTETIGAAARAVAAPGTEILAVCPRAGVPSIEGHFDEAIAAVGVLEQIKAGREQGVDGHVIACFGD-PGLL 79
Cdd:pfam01177   3 GINPNSTASMTRKIVEAARAVLPPHVPVILVTSPDGPDRIESPEDGALAAPALLEALRRLEAAGADAIVIACFTDhPGLD 82

                          90       100
                  ....*....|....*....|....*...
gi 1539640469  80 AARELAQGPVIGIAEAAMHMATMVATRF 107
Cdd:pfam01177  83 ALRELTDIPVLGIAEAAALAALALGGRF 110
 
Name Accession Description Interval E-value
Dcg1 COG4126
Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];
2-107 4.81e-43

Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];


Pssm-ID: 443302  Cd Length: 237  Bit Score: 142.66  E-value: 4.81e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539640469   2 INPNTSLAMTETIGAAARAVAAPGTEILAVCPRAGVPSIEGHFDEAIAAVGVLEQIKAGREQGVDGHVIACFGDPGLLAA 81
Cdd:COG4126     7 INPNTSAAMTERIAAAARAVAAPGTEIEAVTAAFGPASIESRYDEALAAPGVLEAAARAEAEGADAVVIACFGDPGLEAA 86

                          90       100
                  ....*....|....*....|....*.
gi 1539640469  82 RELAQGPVIGIAEAAMHMATMVATRF 107
Cdd:COG4126    87 RELVDIPVVGIAEAAMHAAALLGRRF 112
Asp_Glu_race pfam01177
Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2. ...
 1-107 2.52e-26

Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2.1.1, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase EC:4.1.1.76.


Pssm-ID: 426101  Cd Length: 210  Bit Score: 98.88  E-value: 2.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539640469   1 MINPNTSLAMTETIGAAARAVAAPGTEILAVCPRAGVPSIEGHFDEAIAAVGVLEQIKAGREQGVDGHVIACFGD-PGLL 79
Cdd:pfam01177   3 GINPNSTASMTRKIVEAARAVLPPHVPVILVTSPDGPDRIESPEDGALAAPALLEALRRLEAAGADAIVIACFTDhPGLD 82

                          90       100
                  ....*....|....*....|....*...
gi 1539640469  80 AARELAQGPVIGIAEAAMHMATMVATRF 107
Cdd:pfam01177  83 ALRELTDIPVLGIAEAAALAALALGGRF 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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