E4 orf 3/4 [Vector AdCFP]
List of domain hits
Name | Accession | Description | Interval | E-value | ||
Adeno_E4 super family | cl05114 | Mastadenovirus early E4 13 kDa protein; This family consists of human and simian ... |
34-55 | 7.01e-10 | ||
Mastadenovirus early E4 13 kDa protein; This family consists of human and simian mastadenovirus early E4 13 kDa proteins. Human adenovirus type 9 (Ad9) is unique in eliciting exclusively estrogen-dependent mammary tumours in rats and in not requiring viral E1 region transforming genes for tumorigenicity. E4 codes for an oncoprotein essential for tumourigenesis by Ad9. The actual alignment was detected with superfamily member pfam05385: Pssm-ID: 283128 Cd Length: 108 Bit Score: 50.07 E-value: 7.01e-10
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Adeno_E4_ORF3 super family | cl06131 | Mastadenovirus E4 ORF3 protein; This family consists of several Mastadenovirus E4 ORF3 ... |
2-37 | 4.50e-09 | ||
Mastadenovirus E4 ORF3 protein; This family consists of several Mastadenovirus E4 ORF3 proteins. Early proteins E4 ORF3 and E4 ORF6 have complementary functions during viral infection. Both proteins facilitate efficient viral DNA replication, late protein expression, and prevention of concatenation of viral genomes. A unique function of E4 ORF3 is the reorganization of nuclear structures known as PML oncogenic domains (PODs). The function of these domains is unclear, but PODs have been implicated in a number of important cellular processes, including transcriptional regulation, apoptosis, transformation, and response to interferon. The actual alignment was detected with superfamily member pfam06931: Pssm-ID: 462042 Cd Length: 112 Bit Score: 48.06 E-value: 4.50e-09
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Name | Accession | Description | Interval | E-value | ||
Adeno_E4 | pfam05385 | Mastadenovirus early E4 13 kDa protein; This family consists of human and simian ... |
34-55 | 7.01e-10 | ||
Mastadenovirus early E4 13 kDa protein; This family consists of human and simian mastadenovirus early E4 13 kDa proteins. Human adenovirus type 9 (Ad9) is unique in eliciting exclusively estrogen-dependent mammary tumours in rats and in not requiring viral E1 region transforming genes for tumorigenicity. E4 codes for an oncoprotein essential for tumourigenesis by Ad9. Pssm-ID: 283128 Cd Length: 108 Bit Score: 50.07 E-value: 7.01e-10
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Adeno_E4_ORF3 | pfam06931 | Mastadenovirus E4 ORF3 protein; This family consists of several Mastadenovirus E4 ORF3 ... |
2-37 | 4.50e-09 | ||
Mastadenovirus E4 ORF3 protein; This family consists of several Mastadenovirus E4 ORF3 proteins. Early proteins E4 ORF3 and E4 ORF6 have complementary functions during viral infection. Both proteins facilitate efficient viral DNA replication, late protein expression, and prevention of concatenation of viral genomes. A unique function of E4 ORF3 is the reorganization of nuclear structures known as PML oncogenic domains (PODs). The function of these domains is unclear, but PODs have been implicated in a number of important cellular processes, including transcriptional regulation, apoptosis, transformation, and response to interferon. Pssm-ID: 462042 Cd Length: 112 Bit Score: 48.06 E-value: 4.50e-09
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Name | Accession | Description | Interval | E-value | ||
Adeno_E4 | pfam05385 | Mastadenovirus early E4 13 kDa protein; This family consists of human and simian ... |
34-55 | 7.01e-10 | ||
Mastadenovirus early E4 13 kDa protein; This family consists of human and simian mastadenovirus early E4 13 kDa proteins. Human adenovirus type 9 (Ad9) is unique in eliciting exclusively estrogen-dependent mammary tumours in rats and in not requiring viral E1 region transforming genes for tumorigenicity. E4 codes for an oncoprotein essential for tumourigenesis by Ad9. Pssm-ID: 283128 Cd Length: 108 Bit Score: 50.07 E-value: 7.01e-10
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Adeno_E4_ORF3 | pfam06931 | Mastadenovirus E4 ORF3 protein; This family consists of several Mastadenovirus E4 ORF3 ... |
2-37 | 4.50e-09 | ||
Mastadenovirus E4 ORF3 protein; This family consists of several Mastadenovirus E4 ORF3 proteins. Early proteins E4 ORF3 and E4 ORF6 have complementary functions during viral infection. Both proteins facilitate efficient viral DNA replication, late protein expression, and prevention of concatenation of viral genomes. A unique function of E4 ORF3 is the reorganization of nuclear structures known as PML oncogenic domains (PODs). The function of these domains is unclear, but PODs have been implicated in a number of important cellular processes, including transcriptional regulation, apoptosis, transformation, and response to interferon. Pssm-ID: 462042 Cd Length: 112 Bit Score: 48.06 E-value: 4.50e-09
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Blast search parameters | ||||
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