|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
133-336 |
1.48e-105 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 319.13 E-value: 1.48e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 133 FSKVCVNEDGIQKLQRAVQE-HPVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLGMkLVGELLRMSGAFFMRRT 211
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 212 FGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETL 291
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1537978586 292 YAYELLGIPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSL 336
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREY 203
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
74-641 |
1.16e-104 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 333.81 E-value: 1.16e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 74 VFNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGAIRFFAFVLSKIFKQIFSKVCVneDGIQKLQRAVQEH 153
Cdd:COG2937 126 LLRSPAVRKAIEEEAKSKGISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRV--DNLERLRELAKGH 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 154 PVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGmDFLGMKLVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNG 233
Cdd:COG2937 204 EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAG-INLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERG 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 234 YaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKAR 313
Cdd:COG2937 283 Y-SVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRAL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 314 RILSENFGSIHVYFGDPVSLRSLAsgrlcrNPYNLVPRYIPQKQSEDVHSFVTEVAYRIQlLQIENLA-LNPWLLVVAIL 392
Cdd:COG2937 362 RKLRRRFGRVYVNFGEPISLSEYL------DQHVPDWRESEDLRPEWLRPAVDKLAFEIM-VRINRAAaVNPVNLVALAL 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 393 LQN-QLSMDLDTLVEKTLWLKGLTQAFGgflLWPDNQLPEEVVQssillhSNLASLVNDRVVLKVESGCSEMVkgIVLRH 471
Cdd:COG2937 435 LASpKRALTEAELLAQLDLYLDLLRNVP---YSLSVTLPELTPE------ELLEHLLSLGLIEVEKDGLGDVI--SIDDE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 472 INLLMcSAYRNQLLNIFVRPSLVAVALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRD-FEEGCYLLCKTEAIQM 550
Cdd:COG2937 504 QAVLL-TYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVRQGLLER 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 551 TGKAIIITNKGNAVLEFLIGLFKPFVESYQIVSKYLLHEEEDCFTEKQYLVAVRKFTSQLLDQGASQCFDALSSDLQKNA 630
Cdd:COG2937 583 EGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLGSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDKALFRNF 662
|
570
....*....|.
gi 1537978586 631 LAAFVRLGVVE 641
Cdd:COG2937 663 IQTLREQGYLD 673
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
41-591 |
2.89e-79 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 273.68 E-value: 2.89e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 41 RRHVSDLKFAMKC-YTPTLYRG-VTP-CKPSVIKSIVfNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGA 117
Cdd:PTZ00374 513 RKYFDDVVWTQRVgLTANGWRFaATPgLTPESLTSIL-AQPSIQRLMTALAKKEGASEKDVEARAKAILRTCGDNLNHVQ 591
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 118 IRFFAFVLSKIFKQIFSKVCVNEDGIQKLQRAVQEhP---VVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLGMK 194
Cdd:PTZ00374 592 CRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAM-PrvaVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMG 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 195 LVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRnGYAPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFF--KREVF 272
Cdd:PTZ00374 671 PIATLMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVL-RRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELD 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 273 DTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLASG-RLCrnPYNLVPR 351
Cdd:PTZ00374 750 DVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLRARSLLKRRHGKIHVHIGEPVSLRSFKDHpLQC--PLPFEPK 827
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 352 ---------------YIPQKQSEDVHSFVTEVAYRIQLLQIENLALNPWLLVVAILlqNQLS-----MDLDTLVEKTLWL 411
Cdd:PTZ00374 828 geattsvcktldttpSIARKSSITPPRVLTNIAWHLTHKLQRNTIITPTALVAAVL--ECLGptagaMPLAEVQQGMTWL 905
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 412 KGLTQAFGGFLLWPDNQL-PEEVVQSSIllhSNLASLVNdrvVLKVESGCSEMVKGIVLRhINLLMCSayrNQLLNIFVR 490
Cdd:PTZ00374 906 RTNIRRRGAALSDDCANLnPETMVRKAL---THLQEFVE---ITDEMSEVIYVRQDVVTR-LGVNICS---NQLIHVFMD 975
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 491 PSLVAVALHM-----TPG--LR-KEDVFS--CfSFLRNVFSDEFI-FLPGNTLrDFEEGCYLLCKTEAIQMTgKAIIITN 559
Cdd:PTZ00374 976 EAVVAVVARAfgevtAPHrvRRvEADVLKeqC-QLLRQLLSAEFQdYLPACPY-TFASWHGLELKPVAKEAA-YTIPATA 1052
|
570 580 590
....*....|....*....|....*....|..
gi 1537978586 560 KGNAVLEFLIGLFKPFVESYQIVSKYLLHEEE 591
Cdd:PTZ00374 1053 DRTVLLERLQQLMRHVCEMRSSSPHLLRAEEQ 1084
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
74-495 |
2.01e-62 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 222.41 E-value: 2.01e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 74 VFNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGAIRFFAFVLSKIFKQIFSKVCV-NEDGIQKLqrAVQE 152
Cdd:PRK04974 224 LLASPAIKKAIEDEAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQDG 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 153 HPVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDfLGMKLVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRN 232
Cdd:PRK04974 302 HEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFAR 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 233 GYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKA 312
Cdd:PRK04974 381 GY-SVEYFVEGGRSRTGRLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRG 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 313 RRILSeNFGSIHVYFGDPVSLRSLASGRL--CRNPYNLVPRYIPQKQSEDVHSFVTEVAYRIQllqiENLALNPWLLVVA 390
Cdd:PRK04974 460 IRKLR-NFGQGYVNFGEPIPLNDYLNQHVpeWRESIDPIEEQRPAWLTPAVNNLANQVMVRIN----NAAAANPVNLCAL 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 391 ILLQN-QLSMDLDTLVEK-TLWLKGLTQA-FGGFLLWPDNQlPEEVVQSSILLhsNLASLVNDrvvlkvESGcsEMVkgI 467
Cdd:PRK04974 535 ALLASrQRALDREQLIEQlDLYLQLLRNVpYSSDTTVPEGS-GEELIDHALSL--NKFEVEKD------TLG--DII--S 601
|
410 420
....*....|....*....|....*...
gi 1537978586 468 VLRHINLLMcSAYRNQLLNIFVRPSLVA 495
Cdd:PRK04974 602 LDREQAVLM-TYYRNNILHLFVLPSLIA 628
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
143-282 |
4.19e-29 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 112.37 E-value: 4.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 143 IQKLQRAVQEHPVVLLPSHRSYIDFLMLSFVLYNYDLPvPVIAAGMDFLGMKLVGELLRMSGAFFMRRtfgGNKLYWAVF 222
Cdd:pfam01553 4 VHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNRKDAAGT 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 223 SEYVKTMLRNGYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEpffkrevFDTYFVPISIS 282
Cdd:pfam01553 80 LEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
155-284 |
3.75e-21 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 89.34 E-value: 3.75e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 155 VVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLgMKLVGELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRNGY 234
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1537978586 235 aPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPffkrevfDTYFVPISISYD 284
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
292-644 |
1.16e-18 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 88.34 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 292 YAYELLGIPKPKESTTGLLK-ARRILSENFGSIHVYFGDPVSLRslasGRLcrNPYNLVPRYIPQKQSEDVHSFVTEVAY 370
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLR----EFL--DEQGDRPATDAARRRLALQKLAFEVLS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 371 RIqllqieNLA--LNPWLLVVAILL--------QNQLSMDLDTLVEktlWL--KGLTQAfgGFLLWPDnqlpEEVVQSSi 438
Cdd:pfam19277 75 RI------NRVtpVMPTALVGTVLLtlrgraltLSELIRRVEWLLD---YIraRGGPVA--HFGDLRT----EEVVDRA- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 439 llhsnLASLVNDRVVLKVESGcSEMVKGI--VLRHInllmCSAYRNQLLNIFVRPSLVAVALHMTP-----GLRKEDVFS 511
Cdd:pfam19277 139 -----LDVLGNAGLVTRVDGG-PEPVYYIapEDHFQ----ASFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALWD 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 512 CFSFLRNVFSDEFIFLPGNTLRdfEEgcylLCKTEAIQMTGKAIIITnkGNAVLEFLIG---------LFKPFVESYQIV 582
Cdd:pfam19277 209 QVLRLRDLLKFEFFFPPKEGFR--EN----LRAELDLLDPWEDRVIT--GERDIERLLGrenpdfacfLLWPFIEAYWLV 280
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1537978586 583 SKYLLH-------EEEDCFTEKQylvAVRKftsQLLDQGASQCFDALSSDLQKNALAAFVRLGVVERKK 644
Cdd:pfam19277 281 ADSLADltpdawiDEKDFQDEAL---GLGK---QLYLQGRLSSFESVSKELFKNALQLAENRGLLEVSR 343
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
113-337 |
3.42e-09 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 57.33 E-value: 3.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 113 LRVGAIRFFAFVLSKIFKQIFSKVCVneDGIQKLQRavqEHPVVLLPSHRSYIDFLMLSFVlynydLPVPV-IAAGMDFL 191
Cdd:COG0204 8 LRRFRYRLVRLWARLLLRLLGVRVRV--EGLENLPA---DGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 192 GMKLVGELLRMSGAFFMRRTFGGNKLywAVFsEYVKTMLRNGYAPVeFFLEGTRSRSAKTLIPKFGLLNIVMEpffkrev 271
Cdd:COG0204 78 KIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEALKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE------- 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1537978586 272 FDTYFVPISISYdkileeTLYAYELLGIPKPkesttgllkarrilsenfGSIHVYFGDPVSLRSLA 337
Cdd:COG0204 147 AGVPIVPVAIDG------TERALPKGFLPRP------------------GKVTVRIGPPIDPSDLE 188
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
133-336 |
1.48e-105 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 319.13 E-value: 1.48e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 133 FSKVCVNEDGIQKLQRAVQE-HPVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLGMkLVGELLRMSGAFFMRRT 211
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 212 FGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETL 291
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1537978586 292 YAYELLGIPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSL 336
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREY 203
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
74-641 |
1.16e-104 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 333.81 E-value: 1.16e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 74 VFNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGAIRFFAFVLSKIFKQIFSKVCVneDGIQKLQRAVQEH 153
Cdd:COG2937 126 LLRSPAVRKAIEEEAKSKGISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRV--DNLERLRELAKGH 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 154 PVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGmDFLGMKLVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNG 233
Cdd:COG2937 204 EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAG-INLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERG 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 234 YaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKAR 313
Cdd:COG2937 283 Y-SVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRAL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 314 RILSENFGSIHVYFGDPVSLRSLAsgrlcrNPYNLVPRYIPQKQSEDVHSFVTEVAYRIQlLQIENLA-LNPWLLVVAIL 392
Cdd:COG2937 362 RKLRRRFGRVYVNFGEPISLSEYL------DQHVPDWRESEDLRPEWLRPAVDKLAFEIM-VRINRAAaVNPVNLVALAL 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 393 LQN-QLSMDLDTLVEKTLWLKGLTQAFGgflLWPDNQLPEEVVQssillhSNLASLVNDRVVLKVESGCSEMVkgIVLRH 471
Cdd:COG2937 435 LASpKRALTEAELLAQLDLYLDLLRNVP---YSLSVTLPELTPE------ELLEHLLSLGLIEVEKDGLGDVI--SIDDE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 472 INLLMcSAYRNQLLNIFVRPSLVAVALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRD-FEEGCYLLCKTEAIQM 550
Cdd:COG2937 504 QAVLL-TYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVRQGLLER 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 551 TGKAIIITNKGNAVLEFLIGLFKPFVESYQIVSKYLLHEEEDCFTEKQYLVAVRKFTSQLLDQGASQCFDALSSDLQKNA 630
Cdd:COG2937 583 EGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLGSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDKALFRNF 662
|
570
....*....|.
gi 1537978586 631 LAAFVRLGVVE 641
Cdd:COG2937 663 IQTLREQGYLD 673
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
41-591 |
2.89e-79 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 273.68 E-value: 2.89e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 41 RRHVSDLKFAMKC-YTPTLYRG-VTP-CKPSVIKSIVfNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGA 117
Cdd:PTZ00374 513 RKYFDDVVWTQRVgLTANGWRFaATPgLTPESLTSIL-AQPSIQRLMTALAKKEGASEKDVEARAKAILRTCGDNLNHVQ 591
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 118 IRFFAFVLSKIFKQIFSKVCVNEDGIQKLQRAVQEhP---VVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLGMK 194
Cdd:PTZ00374 592 CRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAM-PrvaVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMG 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 195 LVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRnGYAPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFF--KREVF 272
Cdd:PTZ00374 671 PIATLMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVL-RRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELD 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 273 DTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLASG-RLCrnPYNLVPR 351
Cdd:PTZ00374 750 DVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLRARSLLKRRHGKIHVHIGEPVSLRSFKDHpLQC--PLPFEPK 827
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 352 ---------------YIPQKQSEDVHSFVTEVAYRIQLLQIENLALNPWLLVVAILlqNQLS-----MDLDTLVEKTLWL 411
Cdd:PTZ00374 828 geattsvcktldttpSIARKSSITPPRVLTNIAWHLTHKLQRNTIITPTALVAAVL--ECLGptagaMPLAEVQQGMTWL 905
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 412 KGLTQAFGGFLLWPDNQL-PEEVVQSSIllhSNLASLVNdrvVLKVESGCSEMVKGIVLRhINLLMCSayrNQLLNIFVR 490
Cdd:PTZ00374 906 RTNIRRRGAALSDDCANLnPETMVRKAL---THLQEFVE---ITDEMSEVIYVRQDVVTR-LGVNICS---NQLIHVFMD 975
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 491 PSLVAVALHM-----TPG--LR-KEDVFS--CfSFLRNVFSDEFI-FLPGNTLrDFEEGCYLLCKTEAIQMTgKAIIITN 559
Cdd:PTZ00374 976 EAVVAVVARAfgevtAPHrvRRvEADVLKeqC-QLLRQLLSAEFQdYLPACPY-TFASWHGLELKPVAKEAA-YTIPATA 1052
|
570 580 590
....*....|....*....|....*....|..
gi 1537978586 560 KGNAVLEFLIGLFKPFVESYQIVSKYLLHEEE 591
Cdd:PTZ00374 1053 DRTVLLERLQQLMRHVCEMRSSSPHLLRAEEQ 1084
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
74-495 |
2.01e-62 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 222.41 E-value: 2.01e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 74 VFNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGAIRFFAFVLSKIFKQIFSKVCV-NEDGIQKLqrAVQE 152
Cdd:PRK04974 224 LLASPAIKKAIEDEAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQDG 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 153 HPVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDfLGMKLVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRN 232
Cdd:PRK04974 302 HEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFAR 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 233 GYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKA 312
Cdd:PRK04974 381 GY-SVEYFVEGGRSRTGRLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRG 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 313 RRILSeNFGSIHVYFGDPVSLRSLASGRL--CRNPYNLVPRYIPQKQSEDVHSFVTEVAYRIQllqiENLALNPWLLVVA 390
Cdd:PRK04974 460 IRKLR-NFGQGYVNFGEPIPLNDYLNQHVpeWRESIDPIEEQRPAWLTPAVNNLANQVMVRIN----NAAAANPVNLCAL 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 391 ILLQN-QLSMDLDTLVEK-TLWLKGLTQA-FGGFLLWPDNQlPEEVVQSSILLhsNLASLVNDrvvlkvESGcsEMVkgI 467
Cdd:PRK04974 535 ALLASrQRALDREQLIEQlDLYLQLLRNVpYSSDTTVPEGS-GEELIDHALSL--NKFEVEKD------TLG--DII--S 601
|
410 420
....*....|....*....|....*...
gi 1537978586 468 VLRHINLLMcSAYRNQLLNIFVRPSLVA 495
Cdd:PRK04974 602 LDREQAVLM-TYYRNNILHLFVLPSLIA 628
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
67-631 |
1.79e-51 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 191.08 E-value: 1.79e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 67 PSVIKSIVFNSEEIHYVIKQLSRESLRSVDTLREEASSILEEMSHKLRVGAIRFFAfVLSKIFKQIFS-KVCVNEDGIQK 145
Cdd:PRK03355 181 PRLVKPEILASARFRAGLAKIAAKLGRPPGATVREAGKMLDELVAGWSRVSVDLVS-VLGRLFSRGFDpEIDYDEYELAA 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 146 LQRAVQEHPVVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDfLGMKLVGELLRMSGAFFMRRTFGGNKLYWAVFSEY 225
Cdd:PRK03355 260 LRALLEEHPAVLLFSHRSYIDGLVVPVAMQENRLPPVHVFGGIN-LSFGPMGPIMRRSGMIFIRRNIGDDPLYKYVLREY 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 226 VKTMLRNGYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETLYAYELLGIPKPKES 305
Cdd:PRK03355 339 VGYLVEKRF-NLSWYIEGTRSRTGKLLPPKLGLLSYVADAYLDGRSDDVLLQPVSISFDQLHEIGEYAAEARGGEKTPEG 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 306 TTGLLKARRILSE-NFGSIHVYFGDPVSLRSLasgrlcrnpynLVPRYIPQKQSED-----VHSFVTEVAYRIqlLQIEN 379
Cdd:PRK03355 418 LRWLYNYIKAQGErNYGKIYVRFGEPVSMRQY-----------LGAPHGPLTQDPDakrlaLQKMAFEVAWRI--NQVTP 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 380 LALNPwlLVVAILLqnqlsmdldTLVEKTLWLKGLTQAFGGFLLWPD-NQLP----EEVVQSSILLHSNLASLVNDRVVL 454
Cdd:PRK03355 485 VTATS--LVSLLLL---------GTRGRALTLDELHHTLQDSLDYLErRQLPvstsALRLRDPEGVRAALDALSNGGPVT 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 455 KVESGcSEMVKGIVLRhiNLLMCSAYRNQLLNIFVRPSLVAVALHMTPGLRKEDVFSCF----SFLRNVFSDEFIFLPGN 530
Cdd:PRK03355 554 RVDSG-REPVWYIAPD--DHLVAAFYRNSVIHAFLERAIVELALAAAAHVDEGDRLAAFwdqaMRLRDLLKFEFFFADSD 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 531 TLRD--FEEGCYLLCKTEAIQMTGK---AIIITNKGnavleFLIG--LFKPFVESYQIVSKYLLHEEEDCFTEKQYLVAV 603
Cdd:PRK03355 631 AFRAnlRAEMAWIDPDWEDRLAAGGdeiDALLRAKR-----PLMAhaMLRPFFEAYEVVADVLRDAPPDTIDEKELTALA 705
|
570 580
....*....|....*....|....*...
gi 1537978586 604 RKFTSQLLDQGASQCFDALSSDLQKNAL 631
Cdd:PRK03355 706 LGLGRQYVLQGRVRSSESVSTLLFATAR 733
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
143-282 |
4.19e-29 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 112.37 E-value: 4.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 143 IQKLQRAVQEHPVVLLPSHRSYIDFLMLSFVLYNYDLPvPVIAAGMDFLGMKLVGELLRMSGAFFMRRtfgGNKLYWAVF 222
Cdd:pfam01553 4 VHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNRKDAAGT 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 223 SEYVKTMLRNGYaPVEFFLEGTRSRSAKTLIPKFGLLNIVMEpffkrevFDTYFVPISIS 282
Cdd:pfam01553 80 LEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
133-339 |
4.41e-24 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 99.80 E-value: 4.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 133 FSKVCVNEDGIQKLQRAVQEH-----PVVLLPSHRSYIDFLMLSFVLYNYdLPVPVIAAGMDFLGMKLvgELLRMSGAFF 207
Cdd:cd06551 1 FRYLLLNFFGFVRLEVKGPPPppgggPVLFVSNHSSWWDGLILFLLLERG-LRRDVYGLMDEELLERY--PFFTRLGAFS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 208 MRRTFGGnklYWAVFSEYVKTMLRNGYAPVEFFLEGTRSRSAKTLI-PKFGLLNIvmepffkREVFDTYFVPISISYDKI 286
Cdd:cd06551 78 VDRDSPR---SAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKRPLqFKPGVAHL-------AEKAGVPIVPVALRYTFE 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1537978586 287 LEetlyayellgipkpkesttgllkarrilsENFGSIHVYFGDPVSLRSLASG 339
Cdd:cd06551 148 LF-----------------------------EQFPEIFVRIGPPIPYAETALG 171
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
78-631 |
8.40e-24 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 106.57 E-value: 8.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 78 EEIHYVIKQLSRESlrsvDTLREEASSILEEM--SHKLR-VGAIRFFAFVLSKIFKqifskVCVNEDGIQKLQRAVQEHP 154
Cdd:PRK11915 46 ERLRALADELGRDP----DSVRAEAAGYLREMaaSLDERaVQAWRGFSRWLMRAYD-----VLVDEDQITQLRKLDRKAT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 155 VVLLPSHRSYID-FLMLSFVLYNYDLPVPVIA-AGMDFLGMklvGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRN 232
Cdd:PRK11915 117 LAFAFSHRSYLDgMLLPEVILANRLSPALTFGgANLNFFPM---GAWAKRTGAIFIRRQTKDIPVYRFVLRAYAAQLVQN 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 233 gYAPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEETLYAYELLGIPKPKESTTGLLKA 312
Cdd:PRK11915 194 -HVNLTWSIEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRL 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 313 RRILSENFGSIHVYFGDPVSLRSlasgRLCRnpynlvPRYIPQKQSEDVHSFVTEVAYRIqllqieNLA--LNPWLLVVA 390
Cdd:PRK11915 273 ARQQGERLGRAYLDFGEPLPLRK----RLQE------LRADKSGTGSEIERIALDVEHRI------NRAtpVTPTAVVSL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 391 ILLQNQLSMDLDTLVEKTLWLKGLTQAFGgfllWPDNQLPEEVVQSSI--LLHSNLASlvndrVVLKVESGCSEMVKGIV 468
Cdd:PRK11915 337 ALLGADRSLSISEVLATVRPLASYIAARN----WAVAGAADLTNRSTIrwTLHQMVAS-----GVVSVYDAGTEAVWGIG 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 469 L-RHinlLMCSAYRNQLLNIFVRPSLVAVALHMTPGLRKE------DVFSCFSFLRNVFSDEFIFlPGNTlrDFEEGCyl 541
Cdd:PRK11915 408 EdQH---LVAAFYRNTAIHILVDRAIAELALLAAAETTTNgsvspaTVRDEALSLRELLKFEFLF-SGRA--QFEKDL-- 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 542 lckTEAIQMTGKAIIITNKGNA--VLEFLIG--------LFKPFVESYQIVSKYLLHEEEDCFTEKQYLVAVRKFTSQLL 611
Cdd:PRK11915 480 ---ANEVRLIGSVVDTSKAAAAadVWRLLESadlllahlVLRPFLDAYHIVADRLAAHEDDSFDEEGFLAECLQVGKQWE 556
|
570 580
....*....|....*....|
gi 1537978586 612 DQGASQCFDALSSDLQKNAL 631
Cdd:PRK11915 557 LQRRIASAESRSMELFKTAL 576
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
155-284 |
3.75e-21 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 89.34 E-value: 3.75e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 155 VVLLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLgMKLVGELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRNGY 234
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1537978586 235 aPVEFFLEGTRSRSAKTLIPKFGLLNIVMEPffkrevfDTYFVPISISYD 284
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
292-644 |
1.16e-18 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 88.34 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 292 YAYELLGIPKPKESTTGLLK-ARRILSENFGSIHVYFGDPVSLRslasGRLcrNPYNLVPRYIPQKQSEDVHSFVTEVAY 370
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLR----EFL--DEQGDRPATDAARRRLALQKLAFEVLS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 371 RIqllqieNLA--LNPWLLVVAILL--------QNQLSMDLDTLVEktlWL--KGLTQAfgGFLLWPDnqlpEEVVQSSi 438
Cdd:pfam19277 75 RI------NRVtpVMPTALVGTVLLtlrgraltLSELIRRVEWLLD---YIraRGGPVA--HFGDLRT----EEVVDRA- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 439 llhsnLASLVNDRVVLKVESGcSEMVKGI--VLRHInllmCSAYRNQLLNIFVRPSLVAVALHMTP-----GLRKEDVFS 511
Cdd:pfam19277 139 -----LDVLGNAGLVTRVDGG-PEPVYYIapEDHFQ----ASFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALWD 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 512 CFSFLRNVFSDEFIFLPGNTLRdfEEgcylLCKTEAIQMTGKAIIITnkGNAVLEFLIG---------LFKPFVESYQIV 582
Cdd:pfam19277 209 QVLRLRDLLKFEFFFPPKEGFR--EN----LRAELDLLDPWEDRVIT--GERDIERLLGrenpdfacfLLWPFIEAYWLV 280
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1537978586 583 SKYLLH-------EEEDCFTEKQylvAVRKftsQLLDQGASQCFDALSSDLQKNALAAFVRLGVVERKK 644
Cdd:pfam19277 281 ADSLADltpdawiDEKDFQDEAL---GLGK---QLYLQGRLSSFESVSKELFKNALQLAENRGLLEVSR 343
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
113-337 |
3.42e-09 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 57.33 E-value: 3.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 113 LRVGAIRFFAFVLSKIFKQIFSKVCVneDGIQKLQRavqEHPVVLLPSHRSYIDFLMLSFVlynydLPVPV-IAAGMDFL 191
Cdd:COG0204 8 LRRFRYRLVRLWARLLLRLLGVRVRV--EGLENLPA---DGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 192 GMKLVGELLRMSGAFFMRRTFGGNKLywAVFsEYVKTMLRNGYAPVeFFLEGTRSRSAKTLIPKFGLLNIVMEpffkrev 271
Cdd:COG0204 78 KIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEALKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE------- 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1537978586 272 FDTYFVPISISYdkileeTLYAYELLGIPKPkesttgllkarrilsenfGSIHVYFGDPVSLRSLA 337
Cdd:COG0204 147 AGVPIVPVAIDG------TERALPKGFLPRP------------------GKVTVRIGPPIDPSDLE 188
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
154-344 |
1.71e-08 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 54.58 E-value: 1.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 154 PVVLLPSHRSYIDFLMLSFVLYNYdlPVPVIAAgmDFLGMKLVGELLRMSGAFFMRRtfGGNKLYWAVFsEYVKTMLRNG 233
Cdd:cd07989 25 PVIIVANHQSYLDPLVLGAALPRP--IRFVAKK--ELFKIPFLGWLLRLLGAIPIDR--GNGRSAREAL-REAIEALKEG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1537978586 234 YAPVeFFLEGTRSRSAKTLIPKFGLLNIVMEpfFKREVfdtyfVPISISYdkileeTLYAYELLGIPKPkesttgllkar 313
Cdd:cd07989 98 ESVV-IFPEGTRSRDGELLPFKSGAFRLAKE--AGVPI-----VPVAISG------TWGSLPKGKKLPR----------- 152
|
170 180 190
....*....|....*....|....*....|.
gi 1537978586 314 rilsenFGSIHVYFGDPVSLRSLASGRLCRN 344
Cdd:cd07989 153 ------PGRVTVRIGEPIPPEGLELAEEDRK 177
|
|
| |
