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Conserved domains on  [gi|1536901804|ref|NP_001354712|]
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zinc finger protein 704 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 422-548 6.32e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.51  E-value: 6.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1536901804 422 DGLSSLAP--VSPSQSLASP---PTFPIPdSSRTETPCAKTETklmtpLSRSAPTTLYLVHTDHAYQATPPVTIPgsakf 496
Cdd:pfam05109 497 NGTESKAPdmTSPTSAVTTPtpnATSPTP-AVTTPTPNATSPT-----LGKTSPTSAVTTPTPNATSPTPAVTTP----- 565

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1536901804 497 TPNGSSFSISWQSPPVTFTgIPVSPTHHPVgTGEQRQHAHT------------VLSSPPRGTVS 548
Cdd:pfam05109 566 TPNATIPTLGKTSPTSAVT-TPTPNATSPT-VGETSPQANTtnhtlggtsstpVVTSPPKNATS 627
 
Name Accession Description Interval E-value
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 422-548 6.32e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.51  E-value: 6.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1536901804 422 DGLSSLAP--VSPSQSLASP---PTFPIPdSSRTETPCAKTETklmtpLSRSAPTTLYLVHTDHAYQATPPVTIPgsakf 496
Cdd:pfam05109 497 NGTESKAPdmTSPTSAVTTPtpnATSPTP-AVTTPTPNATSPT-----LGKTSPTSAVTTPTPNATSPTPAVTTP----- 565

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1536901804 497 TPNGSSFSISWQSPPVTFTgIPVSPTHHPVgTGEQRQHAHT------------VLSSPPRGTVS 548
Cdd:pfam05109 566 TPNATIPTLGKTSPTSAVT-TPTPNATSPT-VGETSPQANTtnhtlggtsstpVVTSPPKNATS 627
 
Name Accession Description Interval E-value
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 422-548 6.32e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.51  E-value: 6.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1536901804 422 DGLSSLAP--VSPSQSLASP---PTFPIPdSSRTETPCAKTETklmtpLSRSAPTTLYLVHTDHAYQATPPVTIPgsakf 496
Cdd:pfam05109 497 NGTESKAPdmTSPTSAVTTPtpnATSPTP-AVTTPTPNATSPT-----LGKTSPTSAVTTPTPNATSPTPAVTTP----- 565

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1536901804 497 TPNGSSFSISWQSPPVTFTgIPVSPTHHPVgTGEQRQHAHT------------VLSSPPRGTVS 548
Cdd:pfam05109 566 TPNATIPTLGKTSPTSAVT-TPTPNATSPT-VGETSPQANTtnhtlggtsstpVVTSPPKNATS 627
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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