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Conserved domains on  [gi|1525818758|dbj|BAU59244|]
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RID-beta/14.5 kDa protein [Human adenovirus 4p]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_E3_14_5 super family cl04788
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 35-146 2.30e-03

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


The actual alignment was detected with superfamily member pfam04834:

Pssm-ID: 461451  Cd Length: 100  Bit Score: 35.44  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818758  35 CKFQEPWKFLKCYQLKSDMHPSWIIIMGIVNILACTFFSFVIYPRFDFGWNAPEALWLPPDPDtppqqqqnqahaPPPQP 114
Cdd:pfam04834   2 CRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPF------------CATIF 69

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1525818758 115 RPQYMPILNYEAEPQRAMlPAISYFNLTGGDD 146
Cdd:pfam04834  70 ALAIIAPIDIGRNAIDAM-NEISFFNLAGGDD 100
 
Name Accession Description Interval E-value
Adeno_E3_14_5 pfam04834
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 35-146 2.30e-03

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


Pssm-ID: 461451  Cd Length: 100  Bit Score: 35.44  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818758  35 CKFQEPWKFLKCYQLKSDMHPSWIIIMGIVNILACTFFSFVIYPRFDFGWNAPEALWLPPDPDtppqqqqnqahaPPPQP 114
Cdd:pfam04834   2 CRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPF------------CATIF 69

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1525818758 115 RPQYMPILNYEAEPQRAMlPAISYFNLTGGDD 146
Cdd:pfam04834  70 ALAIIAPIDIGRNAIDAM-NEISFFNLAGGDD 100
 
Name Accession Description Interval E-value
Adeno_E3_14_5 pfam04834
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 35-146 2.30e-03

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


Pssm-ID: 461451  Cd Length: 100  Bit Score: 35.44  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818758  35 CKFQEPWKFLKCYQLKSDMHPSWIIIMGIVNILACTFFSFVIYPRFDFGWNAPEALWLPPDPDtppqqqqnqahaPPPQP 114
Cdd:pfam04834   2 CRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPF------------CATIF 69

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1525818758 115 RPQYMPILNYEAEPQRAMlPAISYFNLTGGDD 146
Cdd:pfam04834  70 ALAIIAPIDIGRNAIDAM-NEISFFNLAGGDD 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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