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Conserved domains on  [gi|1525818756|dbj|BAU59242|]
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CR1-delta/29.7 kDa protein [Human adenovirus 4p]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_E3_CR1 super family cl03594
Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 30-115 1.21e-14

Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).


The actual alignment was detected with superfamily member pfam02440:

Pssm-ID: 367088  Cd Length: 95  Bit Score: 67.77  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818756  30 VNVTEGSNVTLVGVEGAKnTTWTKYHLNGW-KDICNWSVTV-----YTCEGVNLTIVNATSAQNGRIQGQSVSDSEGYYt 103
Cdd:pfam02440  10 VTVYVGSNCTLVGPSGGP-VTWYKFGTDGDgKKFCDGNKPKtpefnHTCNGQNLTLINVTKTYEGTYYGTNFKSSQYED- 87

                          90
                  ....*....|..
gi 1525818756 104 qhtfiYDIKVIP 115
Cdd:pfam02440  88 -----YNVKVLD 94
 
Name Accession Description Interval E-value
Adeno_E3_CR1 pfam02440
Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 30-115 1.21e-14

Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).


Pssm-ID: 367088  Cd Length: 95  Bit Score: 67.77  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818756  30 VNVTEGSNVTLVGVEGAKnTTWTKYHLNGW-KDICNWSVTV-----YTCEGVNLTIVNATSAQNGRIQGQSVSDSEGYYt 103
Cdd:pfam02440  10 VTVYVGSNCTLVGPSGGP-VTWYKFGTDGDgKKFCDGNKPKtpefnHTCNGQNLTLINVTKTYEGTYYGTNFKSSQYED- 87

                          90
                  ....*....|..
gi 1525818756 104 qhtfiYDIKVIP 115
Cdd:pfam02440  88 -----YNVKVLD 94
 
Name Accession Description Interval E-value
Adeno_E3_CR1 pfam02440
Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 30-115 1.21e-14

Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).


Pssm-ID: 367088  Cd Length: 95  Bit Score: 67.77  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818756  30 VNVTEGSNVTLVGVEGAKnTTWTKYHLNGW-KDICNWSVTV-----YTCEGVNLTIVNATSAQNGRIQGQSVSDSEGYYt 103
Cdd:pfam02440  10 VTVYVGSNCTLVGPSGGP-VTWYKFGTDGDgKKFCDGNKPKtpefnHTCNGQNLTLINVTKTYEGTYYGTNFKSSQYED- 87

                          90
                  ....*....|..
gi 1525818756 104 qhtfiYDIKVIP 115
Cdd:pfam02440  88 -----YNVKVLD 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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