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Conserved domains on  [gi|1525818754|dbj|BAU59240|]
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CR1-beta/20.3 kDa protein [Human adenovirus 4p]

Protein Classification

Adeno_E3_CR1 and Adeno_E3_CR2 domain-containing protein( domain architecture ID 10493583)

Adeno_E3_CR1 and Adeno_E3_CR2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_E3_CR1 pfam02440
Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 16-113 5.69e-36

Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).


:

Pssm-ID: 367088  Cd Length: 95  Bit Score: 121.70  E-value: 5.69e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818754  16 FINSFDHKNVTAYVGSNCVLTGYqSHQRVSWYWFDKKNTAYTLCKGNQRPTQRSGlyYSCTNNNITLLQVTKQYSGTYYG 95
Cdd:pfam02440   1 VTPQAGPKNVTVYVGSNCTLVGP-SGGPVTWYKFGTDGDGKKFCDGNKPKTPEFN--HTCNGQNLTLINVTKTYEGTYYG 77

                          90
                  ....*....|....*...
gi 1525818754  96 TNFNTEQDTYYSVKVLDP 113
Cdd:pfam02440  78 TNFKSSQYEDYNVKVLDP 95
Adeno_E3_CR2 pfam02439
Adenovirus E3 region protein CR2; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 164-199 7.47e-14

Adenovirus E3 region protein CR2; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR2 (conserved region 1) is found in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR2 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 50 amino acid region is unknown.


:

Pssm-ID: 111345  Cd Length: 38  Bit Score: 62.75  E-value: 7.47e-14
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1525818754 164 IPRSMIGIIAAVVVCMVIIILCMMYYACYYRKHRLN 199
Cdd:pfam02439   1 IPSSTIAIIVAVVVGMAIIIICMFYYACCYRKHRAY 36
 
Name Accession Description Interval E-value
Adeno_E3_CR1 pfam02440
Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 16-113 5.69e-36

Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).


Pssm-ID: 367088  Cd Length: 95  Bit Score: 121.70  E-value: 5.69e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818754  16 FINSFDHKNVTAYVGSNCVLTGYqSHQRVSWYWFDKKNTAYTLCKGNQRPTQRSGlyYSCTNNNITLLQVTKQYSGTYYG 95
Cdd:pfam02440   1 VTPQAGPKNVTVYVGSNCTLVGP-SGGPVTWYKFGTDGDGKKFCDGNKPKTPEFN--HTCNGQNLTLINVTKTYEGTYYG 77

                          90
                  ....*....|....*...
gi 1525818754  96 TNFNTEQDTYYSVKVLDP 113
Cdd:pfam02440  78 TNFKSSQYEDYNVKVLDP 95
Adeno_E3_CR2 pfam02439
Adenovirus E3 region protein CR2; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 164-199 7.47e-14

Adenovirus E3 region protein CR2; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR2 (conserved region 1) is found in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR2 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 50 amino acid region is unknown.


Pssm-ID: 111345  Cd Length: 38  Bit Score: 62.75  E-value: 7.47e-14
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1525818754 164 IPRSMIGIIAAVVVCMVIIILCMMYYACYYRKHRLN 199
Cdd:pfam02439   1 IPSSTIAIIVAVVVGMAIIIICMFYYACCYRKHRAY 36
 
Name Accession Description Interval E-value
Adeno_E3_CR1 pfam02440
Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 16-113 5.69e-36

Adenovirus E3 region protein CR1; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).


Pssm-ID: 367088  Cd Length: 95  Bit Score: 121.70  E-value: 5.69e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818754  16 FINSFDHKNVTAYVGSNCVLTGYqSHQRVSWYWFDKKNTAYTLCKGNQRPTQRSGlyYSCTNNNITLLQVTKQYSGTYYG 95
Cdd:pfam02440   1 VTPQAGPKNVTVYVGSNCTLVGP-SGGPVTWYKFGTDGDGKKFCDGNKPKTPEFN--HTCNGQNLTLINVTKTYEGTYYG 77

                          90
                  ....*....|....*...
gi 1525818754  96 TNFNTEQDTYYSVKVLDP 113
Cdd:pfam02440  78 TNFKSSQYEDYNVKVLDP 95
Adeno_E3_CR2 pfam02439
Adenovirus E3 region protein CR2; Early region 3 (E3) of human adenoviruses (Ads) codes for ...
 164-199 7.47e-14

Adenovirus E3 region protein CR2; Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR2 (conserved region 1) is found in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR2 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 50 amino acid region is unknown.


Pssm-ID: 111345  Cd Length: 38  Bit Score: 62.75  E-value: 7.47e-14
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1525818754 164 IPRSMIGIIAAVVVCMVIIILCMMYYACYYRKHRLN 199
Cdd:pfam02439   1 IPSSTIAIIVAVVVGMAIIIICMFYYACCYRKHRAY 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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