|
Name |
Accession |
Description |
Interval |
E-value |
| PQQ_enz_alc_DH |
TIGR03075 |
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic ... |
44-593 |
0e+00 |
|
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Genes in this family often are found adjacent to the PQQ biosynthesis genes themselves. An unusual, strained disulfide bond between adjacent Cys residues contributes to PQQ-binding, as does a Trp residue that is part of a PQQ enzyme repeat (see pfam01011). Characterized members include the dehydrogenase subunit of a membrane-anchored, three subunit alcohol (ethanol) dehydrogenase of Gluconobacter suboxydans, a homodimeric ethanol dehydrogenase in Pseudomonas aeruginosa, and the large subunit of an alpha2/beta2 heterotetrameric methanol dehydrogenase in Methylobacterium extorquens.
Pssm-ID: 274419 [Multi-domain] Cd Length: 527 Bit Score: 872.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 44 VTWEDIANDHLTTKDVLQYGMGTNAQRWSPLAQVNDQNVFKLTPAWSYSFGdeKQRGQESQAIVSDGVVYVTGSYSRVFA 123
Cdd:TIGR03075 6 VTNEDLLNDAKDPSDWLTYGGGYAGQRYSPLDQINTDNVKKLQPAWTFSLG--KQRGQESQPLVVDGVMYVTTSYSRVYA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 124 LDAKTGKRLWTYNHRLPDNIRP--CCDVVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKKFGDHSAGYTMTGAPVL 201
Cdd:TIGR03075 84 LDAKTGKILWKYDPKLPDDIIPvmCCDVVNRGAALYDGKVFFGTLDARLVALDAKTGKVVWSKKNGDYKKGYTITAAPLV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 202 IKDKtsgkvlLIHGSSGDEFGVVGQLFARDPDTGEEVWMRPFVEGHMGRLNGKDSTPTGDVKAPSWPDDkttetgkveAW 281
Cdd:TIGR03075 164 VKGK------VITGISGGEFGVRGYVTAYDAKTGKLVWRRYTVPGDMGYLKKTGKPVGGDPGAKTWPGD---------AW 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 282 SHGGGAPWQSASFDPETNTIIVGAGNPGPWNTWARtakdgnphDFDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGN 361
Cdd:TIGR03075 229 KTGGGATWGTGSYDPETNLIYFGTGNPAPWNSHLR--------PGDNLYTSSIVARDPDTGKIKWHYQTTPHDEWDYDGV 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 362 NELVLFDYKgKDGKVVKATGHADRNGFFYVVDRNNGKLQNAFPFVDNITWASHIDLKTGRPVENEGQRPakplPGETKGK 441
Cdd:TIGR03075 301 NEMILFDLK-KDGKPRKLLAHADRNGFFYVLDRTNGKLLSAEPFVDKVNWATGVDLKTGRPIEVPEARS----TDGKKGK 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 442 PVEVSPPFLGGKNWNPMAYSQDTGLFYIPGNQWKEEYWTEEVNYKKGSAYLGMGFRIKRMYDDHVGTLRAMDPTTGKLVW 521
Cdd:TIGR03075 376 PVEVCPGFLGGKNWQPMAYSPKTGLFYVPANHVCMDYWPEKVSYKKGAAYLGAGFTIKPPPDDHIGSLIAWDPITGKIVW 455
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1524128033 522 EHKEHLPLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGG 593
Cdd:TIGR03075 456 EHKEDFPLWGGVLATAGDLVFTGTLEGYFKAFDAKTGEELWKFKTGSGIVGPPVTYEQDGKQYVAVLSGWGG 527
|
|
| PQQ_ADH_I |
cd10277 |
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ... |
49-620 |
0e+00 |
|
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.
Pssm-ID: 199835 [Multi-domain] Cd Length: 529 Bit Score: 849.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 49 IANDHLTTKDVLQYGMGTNAQRWSPLAQVNDQNVFKLTPAWSYSFGDeKQRGQESQAIVSDGVVYVTGSYSRVFALDAKT 128
Cdd:cd10277 1 LLNDAKETGNWLTYGRGYNGQRYSPLKQINTDNVKNLVPAWSFSFGG-KQRGQESQPIVNDGVMYVTTSYNRVFAIDAKT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 129 GKRLWTYNHRLPDNIRPCCDVVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKKFGDHSAGYTMTGAPVLIKDKtsg 208
Cdd:cd10277 80 GKELWKYKHRLPEDIRPCCDVVNRGVALYGDKVYFGTLDAHLVALDAKTGKVVWKKKVADYKAGYSMTLAPLVVKGK--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 209 kvlLIHGSSGDEFGVVGQLFARDPDTGEEVWMRPFVEGHMGRLNGKdstptgdvkapswpddktteTGKVEAWSHGGGAP 288
Cdd:cd10277 157 ---VIVGVSGGEFGVRGFIAALDAETGKEVWRTYTVPGPGEPGSTD--------------------TWPGDAWKTGGGAT 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 289 WQSASFDPETNTIIVGAGNPGPWNTWartakdgnPHDFDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFD 368
Cdd:cd10277 214 WLTGTYDPETNLLYWGVGNPAPWNGD--------LRPGDNLYTSSVLALDPDTGKIKWHYQYTPNDTWDYDGVNEPVLFD 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 369 YKgKDGKVVKATGHADRNGFFYVVDRNNGKLQNAFPFVDNITWAShIDLKTGRPVENEGQRPAKplpgetKGKPVEVSPP 448
Cdd:cd10277 286 YT-KNGKPVKALVHADRNGFFYVLDRTNGKLIWATPFVKKITWAS-IDLKTGRPIYDEDKVPPK------KGKTVDFCPS 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 449 FLGGKNWNPMAYSQDTGLFYIPGNQWKEEYWTEEVNYKKGSAYLGMGFRIKRMYDDHVGTLRAMDPTTGKLVWEHKEHLP 528
Cdd:cd10277 358 FLGGKNWPPMAYSPDTGLFYVPANHWCMDLTGEPVSYKKGAAYLGAGFTIKPPFEDHIGELQAIDPTTGKKVWEHKTPLP 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 529 LWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAELTKP 608
Cdd:cd10277 438 LWGGVLTTAGGLVFTGTPDGYFRAFDAKTGKELWEFQTGSGIIGPPVTWEVDGKQYVAVLSGWGGAAPLWGGDMAKLLKN 517
|
570
....*....|..
gi 1524128033 609 VAQGGSFWVFKI 620
Cdd:cd10277 518 VPQGGSLWVFAL 529
|
|
| Gcd |
COG4993 |
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism]; |
55-621 |
0e+00 |
|
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
Pssm-ID: 444017 [Multi-domain] Cd Length: 515 Bit Score: 681.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 55 TTKDVLQYGMGTNAQRWSPLAQVNDQNVFKLTPAWSYSFGDEKQRGQESQAIVSDGVVYVTGSYSRVFALDAKTGKRLWT 134
Cdd:COG4993 1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLPERGHEATPLVVDGVLYVCTPHNRVFALDAATGKELWR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 135 YNHRLPDNIrPCCDVVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKKFGDHSAGYTMTGAPVLIKDKtsgkvlLIH 214
Cdd:COG4993 81 YDPKLPDDA-ACCDVVNRGVAYYDGRIFLGTLDGRLVALDAKTGKVCWDVKVGDPKKGYTITSAPLVVKDK------VIV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 215 GSSGDEFGVVGQLFARDPDTGEEVWMRPFVEGHmgrlngkdstptGDVKAPSWPDDkttetgkvEAWSHGGGAPWQSASF 294
Cdd:COG4993 154 GGSGGEFGPRGVVRAYDARTGKLVWRFDTIPDP------------GEPGAETWPPG--------DTWKRGGGNVWGTMSY 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 295 DPETNTIIVGAGNPGP-WNTWARtakdgnphDFDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKgKD 373
Cdd:COG4993 214 DPELGLVYLPTGNPAPdWNGGQR--------PGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDLP-VD 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 374 GKVVKATGHADRNGFFYVVDRNNGKLQNAFPFVDNITWASHIDLKTGRPVENegqrpakplPGETKGKPVEVSPPFLGGK 453
Cdd:COG4993 285 GKTRKALVQATKNGFIYVLDRETGEPLVTQPFVKPPNWATEIDMWGATPIQT---------PPSLDGKTTLICPGALGGK 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 454 NWNPMAYSQDTGLFYIPGNQWKEEYWTEEVNYKKGSAYLGMGFRIKRMYDDHVGTLRAMDPTTGKLVWEHKEHLPLWAGV 533
Cdd:COG4993 356 NWGPAAYDPETGLLYVPANELCMDYELVPREYQAGAPYLGATLTMYPCPAPPWGTLTAIDLNTGKIVWQVPLGFPNWGGP 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 534 LATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGGAVPLWGgdmaeltkPVAQGG 613
Cdd:COG4993 436 LATAGGLVFIGTLDGYLRAFDAKTGKELWKFRLPSGGQATPMTYEVDGKQYVAVAAGGGGWLGLGL--------YTPQGD 507
|
....*...
gi 1524128033 614 SFWVFKIP 621
Cdd:COG4993 508 YLIAFALP 515
|
|
| PQQ_DH_like |
cd00216 |
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ... |
79-619 |
0e+00 |
|
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.
Pssm-ID: 199833 [Multi-domain] Cd Length: 434 Bit Score: 557.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 79 DQNVFKLTPAWSYSFGDEKQRGQESQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPDN-IRPCCDVVNRGAAIY 157
Cdd:cd00216 1 ADNVFQLTPAWSFSTGDGGNRGSELTPIVVDGVMYATTSFSRVFALDADDGKEIWSYDPALKDGwFEACCDLVNRGVAVW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 158 GDKIYFGTLDARVIALDKNTGKVVWNKKFGDHSAGYTMTGAPVLIKDKtsgkvlLIHGSSGDEFGVVGQLFARDPDTGEE 237
Cdd:cd00216 81 GGKVYIGVLDGRVYALNAETGKVAWKVKNADVLGGYTATSAPVVVDGL------VIIGSSGDEFGVRGYLTAYDVATGEE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 238 VWMRPFVEGHMGRLNGKDSTPTgdvkapswpdDKTTETGKVEAWSHGGGAPWQSASFDPETNTIIVGAGNPGPWNTWart 317
Cdd:cd00216 155 KWRFYLVMPDPNLLPGKDSTVT----------DRNTPTGDEHTWTSGGGTGWSSAAYDAELNLIYVGGGNPTPWNWG--- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 318 akdGNPHDFDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYKGKdGKVVKATGHADRNGFFYVVDRNNG 397
Cdd:cd00216 222 ---GNRTPGDNLYTSSIVAVNADTGEMKWQYQTTPHDAWDYDGDNTPVLADIKVK-GKKVKVLFAPAKNGNFYVLDRRNG 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 398 KLQNAFPFVdnitwashidlktgrpvenegqrpakplpgetkgkpvevsppflggknwnPMAYSQDTGLFYIPGNqwkee 477
Cdd:cd00216 298 ELVSARPLV--------------------------------------------------PDSYDPDRELFYVPAN----- 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 478 ywteevnykkgsaylgmgfrikrmyddhvGTLRAMDPTTGKLVWEHKEHLPLWAGVLATKGNLVFTGTGDGFFKAFDAKT 557
Cdd:cd00216 323 -----------------------------GRIMALDPVTGVVVWEKSELHPLLGGPLSTAGNLVFVGTSDGYLKAYNADT 373
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1524128033 558 GKELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGGAVPLWGGdMAELTKPVAQGGSFWVFK 619
Cdd:cd00216 374 GEKLWQQKVPSGFQAEPVTYEVDGEQYVLIQAGGGGAFPLWGG-MADLTRGTQMGGTVVVYK 434
|
|
| PQQ_ADH_II |
cd10279 |
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ... |
60-620 |
2.74e-169 |
|
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199837 [Multi-domain] Cd Length: 549 Bit Score: 493.70 E-value: 2.74e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 60 LQYGMGTNAQRWSPLAQVNDQNVFKLTPAWSYSFGDEkqRGQESQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRL 139
Cdd:cd10279 4 LSYGRDYDEQRFSPLTQINRSNVGQLGLAWYFDLDTN--RGQEATPLVVDGVMYVSGPWSVVYALDARTGKLLWQYDPEV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 140 PDNI--RPCCDVVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKKFGDHSAGYTMTGAPVLIKdktsGKVLLihGSS 217
Cdd:cd10279 82 DRESgrKACCDVVNRGVAVWDGKVFVGTLDGRLIALDAKTGKEVWSVDTIDPRKPYTITGAPRVAK----GKVVI--GNG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 218 GDEFGVVGQLFARDPDTGEEVWmRPFVEGhmGRLNGKDSTPTGDVKAPSWPDDKTTETGkveawshGGGAPWQSASFDPE 297
Cdd:cd10279 156 GAEFGVRGYVSAYDAETGKLVW-RFYTVP--GNPAKPFEHASLEAAAATWWTGEWWRTG-------GGGTVWDSITYDPE 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 298 TNTIIVGAGNPGPWNTWARTAKDGnphdfDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYK--GKDGK 375
Cdd:cd10279 226 LDLLYIGTGNGSPWNRKVRSPGGG-----DNLFLSSIVALDADTGRYKWHYQTTPGDTWDYTATQPIILADLEidGKPRK 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 376 VVKatgHADRNGFFYVVDRNNGKLQNAFPFVDnITWASHIDLKTGRPVENEGQRPAKplpgetkgKPVEVSPPFLGGKNW 455
Cdd:cd10279 301 VLM---HAPKNGFFYVLDRATGKLLSAEPFVP-VNWATGIDLKTGRPIENPEARYTK--------GPKLVFPGPLGAHNW 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 456 NPMAYSQDTGLFYIPGNQWKEEYWTEEVNYKK--GSAYLGMGF--------RIKRMYDDHVGTLRAMDPTTGKLVWEHKE 525
Cdd:cd10279 369 HPMSYNPDTGLVYIPAQEIPAVYEDDPGDFGYnpLGWNTGITPdatpppaaAKRALRKATRGRLVAWDPVTQKAAWRVEH 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 526 HLPLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGGAVPLWGGDmAEL 605
Cdd:cd10279 449 PGPWNGGVLATAGNLVFQGTADGELAAYDARTGEKLWSFDTGSGIVAAPMTYSVDGEQYVAVLAGWGGAGALSGGP-PGA 527
|
570
....*....|....*
gi 1524128033 606 TKPVAQGGSFWVFKI 620
Cdd:cd10279 528 AGKVQNPGRLLVFKL 542
|
|
| PQQ_MDH |
cd10278 |
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ... |
63-620 |
3.72e-161 |
|
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.
Pssm-ID: 199836 [Multi-domain] Cd Length: 553 Bit Score: 473.35 E-value: 3.72e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 63 GMGTNAQRWSPLAQVNDQNVFKLTPAWSYSFGdeKQRGQESQAIVSDGVVYVTGSY-SRVFALD-AKTGKRLWTYNHRLP 140
Cdd:cd10278 5 GKDYANTRYSPLAQINKDNVKNLKVAWTFSTG--VLRGHEGAPLVVGDTMYVVTPFpNNVYALDlNDPGKILWKYKPKQD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 141 DNIRP--CCDVVNRGAAiYGD-KIYFGTLDARVIALDKNTGKVVWNKKFGDHSAGYTMTGAPVLIKDKtsgkvlLIHGSS 217
Cdd:cd10278 83 PSAVAvaCCDVVNRGLA-YADgKIFFNQLDGHLVALDAKTGKEVWKVKNGDPKVGETLTMAPLVVKDK------VIVGIS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 218 GDEFGVVGQLFARDPDTGEEVWmRPFVEG-HMGRLNGKDSTPTG------DVKAPSWPDDkttetgkveAWSHGGGAPWQ 290
Cdd:cd10278 156 GGEFGVRGYVTAYDLKTGKLVW-RAYSTGpDKDVLIGPDFNPFNphdggkDLGLSTWPGD---------AWKIGGGTNWG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 291 SASFDPETNTIIVGAGNPGPWNTWARTAkdgnphdfDSLYTSGQVGVDPSTGEVKWFYQHTPNDAWDFSGNNELVLFDYK 370
Cdd:cd10278 226 WYSYDPKLNLVYYGTGNPGPWNPTQRPG--------DNKWSMTIFARDPDTGEAKWAYQMTPHDEWDYDGVNEMILVDQT 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 371 gKDGKVVKATGHADRNGFFYVVDRNNGKLQNAFPFvDNITWASHIDLKTGRPVENegqrPAKPlpGETKGKPVEVSPPFL 450
Cdd:cd10278 298 -VDGKKRKLLVHFDRNGFVYTLDRTTGELLSAEKF-DPVNNWKGVDLKTGRPVKD----PEKS--THMDHNVTDICPSAM 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 451 GGKNWNPMAYSQDTGLFYIPGNQWKEEYWTEEVNYKKGSAYLGMGFRIKRMYDDHVGTLRAMDPTTGKLVWEHKEHLPLW 530
Cdd:cd10278 370 GGKDQQPSSYSPKTGLFYVPTNHLCMDYEPFEVNYTAGQPYVGATLAMYPGPGGHMGQFKAWDPVTGKTKWEIKERFPVW 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 531 AGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGG--AVPLWGGD------- 601
Cdd:cd10278 450 SGTLATAGGLVFYGTLDGWFKAVDAKTGKLLWKFKLPSGIIGNPITYKHDGKQYVAVLSGVGGwaGVGVAAGLrdptagl 529
|
570 580
....*....|....*....|....
gi 1524128033 602 -----MAELTKPVAQGGSFWVFKI 620
Cdd:cd10278 530 gavgaFKDLPNYTQMGGTLYVFSL 553
|
|
| PQQ_mGDH |
cd10280 |
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ... |
62-593 |
1.31e-60 |
|
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199838 [Multi-domain] Cd Length: 616 Bit Score: 212.82 E-value: 1.31e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 62 YGMGTNAQRWSPLAQVNDQNVFKLTPAWSYSFGDEKQRGQ-----ESQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYN 136
Cdd:cd10280 4 YGGDPGGTRYSPLDQITPDNVGKLKVAWTYHTGDLPGPDGnegtfEATPLKVGGTLYLCTPHNRVIALDAATGKELWRFD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 137 ---HRLPDNIRPCCdvvnRGAAIYGDK---------IYFGTLDARVIALDKNTGKVVWNkkFGDH-------------SA 191
Cdd:cd10280 84 pkaGADAAPGHQTC----RGVSYWEDGaaaaacarrIFFGTGDARLIALDARTGKPCPD--FGDNgvvdlreglgrvkPG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 192 GYTMTGAPVLIKDktsgkvLLIHGSSGDEFGVV----GQLFARDPDTGEEVWMrpFvegHMGRLNGKDSTPTGdvkapsw 267
Cdd:cd10280 158 FYSSTSPPTVYGD------LVIVGSAVADNQAVdapsGVIRAFDVRTGKLVWA--F---DTIPPPGEAGPDTA------- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 268 pdDKTTETGKVEAWSHgggapwqsASFDPETNTIIVGAGNPGPwntwartakdgnphDF-------DSLYTSGQVGVDPS 340
Cdd:cd10280 220 --GAWYTRGGPNVWAG--------MSADEKLGLVYLPTGSATP--------------DFyggdrpgDNLFANSLVALDAA 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 341 TGEVKWFYQHTPNDAWDFSGNNELVLFDYKGkDGKVVKATGHADRNGFFYVVDRNNGKlqnafPFVdnitwashidlktg 420
Cdd:cd10280 276 TGKRRWHFQTVHHDLWDYDLPAQPTLVDVPR-DGKTVPAVAQPTKQGFVFVLDRRTGK-----PLW-------------- 335
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 421 rPVEnegQRPAKP--LPGE---------TKGKP---------------------------------------VEVS---P 447
Cdd:cd10280 336 -PVE---ERPVPQgdVPGErtsptqpfpTLPPPfarqglteddmwgatpfdqlacriqfrslryeglftppsLDGTlifP 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 448 PFLGGKNWNPMAYSQDTGLFYIPGNQ---------------------WKEEYWTEEVNYKKGSAYLGMgfRIKRMYDDHV 506
Cdd:cd10280 412 GNDGGANWGGAAVDPERGILYVNSNRlpfviqlvprapgdpagvaggGEGGGGGGGPSPQAGTPYGVG--RGRFLSPLGL 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 -------GTLRAMDPTTGKLVWEH-----------KEHLPL------WAGVLATKGNLVFTG-TGDGFFKAFDAKTGKEL 561
Cdd:cd10280 490 pcqappwGTLTAIDLNTGKILWQVplgtvpdlgpkGIPLPIptgtpnLGGPVVTAGGLVFIAaTQDNYLRAFDKATGKEL 569
|
650 660 670
....*....|....*....|....*....|..
gi 1524128033 562 WKFQTGSGIVSPPITWEQDGEQYIGVTVGYGG 593
Cdd:cd10280 570 WEARLPAGGQATPMTYEVDGKQYVVIAAGGHG 601
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
72-240 |
1.49e-18 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 87.95 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 72 SPLAQVNDQnvFKLTPAWSYSFGDEKQRGQESQAI-VSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPdnirpccdvV 150
Cdd:COG1520 21 APLPEFEPS--VKVKQLWSASVGDGVGKGYSRLAPaVAGDRVYAADADGRVAALDAATGKELWRVDLGEP---------L 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 151 NRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKKfgdhsagytmTGAPVLIKDKTSGKVLLIHgsSGDefgvvGQLFAR 230
Cdd:COG1520 90 SGGVGADGGLVVVGTEDGEVIALDADDGEELWRAR----------LSSEVLAAPAVAGGRVVVR--TGD-----GRVYAL 152
|
170
....*....|
gi 1524128033 231 DPDTGEEVWM 240
Cdd:COG1520 153 DAATGERLWS 162
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
81-348 |
2.80e-17 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 83.92 E-value: 2.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 81 NVFKLTPAWSYSFGDEKQRGQESQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNhrLPDNIRpccdvVNRGAAIYGDK 160
Cdd:cd10276 10 PEFDPEVLWSKSVGNGGMAGIDLTPVVAGDMVYAADANGQVSAFNATTGKIIWETS--LSGKGF-----LGGTPAVGNGK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 161 IYFGTLDARVIALDKNTGKVVWNKKFGDHSAgytmtGAPVLIKDktsGKVLLihGSSGdefgvvGQLFARDPDTGEEVWM 240
Cdd:cd10276 83 IFVGTESGYLYALDAKDGSELWRTEVSDSQL-----LSPPTYAD---GKIYV--GTGD------GRLYYCNAETGKVVWN 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 241 RPFvEGHMGRLNGkDSTPTGDvkapswpDDK---TTETGKVEAWSHGGGAP-WQ------------------SASFDPET 298
Cdd:cd10276 147 RTS-TAPELSLRG-GAAPVGA-------YDVvfvGDGNGTVVALNTGTGVDiWEfsvseprgrtelprmidsSVTYVVVG 217
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1524128033 299 NTIIVGAGNPGPW----------NTWARTAKDGNPHD-FDSLYTS---GQV-GVDPSTGEVKWFY 348
Cdd:cd10276 218 GYLYSTSYQGYLValdfesgqflWSRKASGGTSTSTDaNGRVYVGdgeGSLyCLDASTGDELWSQ 282
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
72-239 |
5.39e-17 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 83.44 E-value: 5.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 72 SPLAQVNDQnvFKLTPAWSYSFGDekqrGQES-----QAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPDNIRPc 146
Cdd:PRK11138 33 SPLPQVENQ--FTPTTVWSTSVGD----GVGDyysrlHPAVAYNKVYAADRAGLVKALDADTGKEIWSVDLSEKDGWFS- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 147 cdvVNRGAAIYG------DKIYFGTLDARVIALDKNTGKVVWNKKfgdhSAGYTMTgAPVLikdktSGKVLLIHGSSgde 220
Cdd:PRK11138 106 ---KNKSALLSGgvtvagGKVYIGSEKGQVYALNAEDGEVAWQTK----VAGEALS-RPVV-----SDGLVLVHTSN--- 169
|
170
....*....|....*....
gi 1524128033 221 fgvvGQLFARDPDTGEEVW 239
Cdd:PRK11138 170 ----GMLQALNESDGAVKW 184
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
72-239 |
1.45e-14 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 75.74 E-value: 1.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 72 SPLAQVndQNVFKLTPAWSYSFGD-EKQRGQESQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTynHRLPDNIRpccdvv 150
Cdd:TIGR03300 29 AELPEF--QPTVKVDQVWSASVGDgVGHYYLRLQPAVAGGKVYAADADGTVAALDAETGKRLWR--VDLDERLS------ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 151 nRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKKfgdhsagytmTGAPVLIKDKTSGKVLLIHGSSgdefgvvGQLFAR 230
Cdd:TIGR03300 99 -GGVGADGGLVFVGTEKGEVIALDAEDGKELWRAK----------LSSEVLSPPLVANGLVVVRTND-------GRLTAL 160
|
....*....
gi 1524128033 231 DPDTGEEVW 239
Cdd:TIGR03300 161 DAATGERLW 169
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
107-346 |
1.98e-14 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 73.21 E-value: 1.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 107 VSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPDNIRPccdvvnrgaAIYGDKIYFGTLDARVIALDKNTGKVVWNKKF 186
Cdd:pfam13360 31 VDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAP---------LVAGGRVFVVAGDGSLIALDAADGRRLWSYQR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 187 GDHSAGYTMTGAPVLikdktSGKVLLIHGSSGDefgvvgqLFARDPDTGEEVWM----RPFVEGHMGRLNGKDSTPTGDv 262
Cdd:pfam13360 102 SGEPLALRSSGSPAV-----VGDTVVAGFSSGK-------LVALDPATGKVRWEaplaAPRGTNELERLVDITGTPVVA- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 263 kapswpddktteTGKVEAWSHGGGApwqsASFDPETNTIivgagnpgpwnTWARTAKDGNPH--DFDSLY---TSGQV-G 336
Cdd:pfam13360 169 ------------GGRVFASAYQGRL----VAFDAATGRR-----------LWTREISGPNGPilDGDLLYvvsDDGELyA 221
|
250
....*....|
gi 1524128033 337 VDPSTGEVKW 346
Cdd:pfam13360 222 LDRATGAVVW 231
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
103-243 |
1.16e-11 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 66.76 E-value: 1.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 103 SQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPdnirpccDVVNRGAA---IYGDKIYFGTLDARVIALDKNTGK 179
Cdd:COG1520 131 AAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQRPVP-------ALTLRGTSspvIVGGAVLVGFANGKLVALDLANGQ 203
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1524128033 180 VVWNKKFGDhSAGYT-------MTGAPVLIkdktsgkvllihgssGDEFGVV---GQLFARDPDTGEEVWMRPF 243
Cdd:COG1520 204 PLWEQRVAQ-PRGRTelerlvdVDGTPVVD---------------GGVVYAVayqGRLAALDLRSGRVLWSRDL 261
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
507-574 |
5.19e-11 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 64.83 E-value: 5.19e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHLPLWAGVlATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPP 574
Cdd:COG1520 67 GRVAALDAATGKELWRVDLGEPLSGGV-GADGGLVVVGTEDGEVIALDADDGEELWRARLSSEVLAAP 133
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
507-574 |
3.19e-10 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 62.26 E-value: 3.19e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHLPLWAGVLATkGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPP 574
Cdd:TIGR03300 75 GTVAALDAETGKRLWRVDLDERLSGGVGAD-GGLVFVGTEKGEVIALDAEDGKELWRAKLSSEVLSPP 141
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
507-574 |
4.73e-10 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 60.11 E-value: 4.73e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHLPLWAGVlATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPP 574
Cdd:pfam13360 3 GVVTALDAATGAELWRVDLETGLGGGV-AVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAP 69
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
103-243 |
9.19e-10 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 60.72 E-value: 9.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 103 SQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPdnirpccDVVNRGAA---IYGDKIYFGTLDARVIALDKNTGK 179
Cdd:TIGR03300 139 SPPLVANGLVVVRTNDGRLTALDAATGERLWTYSRVTP-------PLTLRGSAspvIADGGVLVGFAGGKLVALDLQTGQ 211
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1524128033 180 VVWNKKFGdHSAGYT-------MTGAPVLikdktSGKVLlihgssgdeFGVV--GQLFARDPDTGEEVWMRPF 243
Cdd:TIGR03300 212 PLWEQRVA-LPKGRTelerlvdVDGDPVV-----DGGQV---------YAVSyqGRVAALDLRSGRVLWKRDA 269
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
507-586 |
1.07e-08 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 57.34 E-value: 1.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEH-LPLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPPITWEqDGEQYI 585
Cdd:cd10276 48 GQVSAFNATTGKIIWETSLSgKGFLGGTPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSDSQLLSPPTYA-DGKIYV 126
|
.
gi 1524128033 586 G 586
Cdd:cd10276 127 G 127
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
539-574 |
8.85e-08 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 48.34 E-value: 8.85e-08
10 20 30
....*....|....*....|....*....|....*.
gi 1524128033 539 NLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSPP 574
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| Luminal_IRE1_like |
cd09213 |
The Luminal domain, a dimerization domain, of Inositol-requiring protein 1-like proteins; The ... |
108-329 |
4.65e-07 |
|
The Luminal domain, a dimerization domain, of Inositol-requiring protein 1-like proteins; The Luminal domain is a dimerization domain present in Inositol-requiring protein 1 (IRE1), eukaryotic translation Initiation Factor 2-Alpha Kinase 3 (EIF2AK3), and similar proteins. IRE1 and EIF2AK3 are serine/threonine protein kinases (STKs) and are type I transmembrane proteins that are localized in the endoplasmic reticulum (ER). They are kinase receptors that are activated through the release of BiP, a chaperone bound to their luminal domains under unstressed conditions. This results in dimerization through their luminal domains, allowing trans-autophosphorylation of their kinase domains and activation. They play roles in the signaling of the unfolded protein response (UPR), which is activated when protein misfolding is detected in the ER in order to decrease the synthesis of new proteins and increase the capacity of the ER to cope with the stress. IRE1, also called Endoplasmic reticulum (ER)-to-nucleus signaling protein (or ERN), contains an endoribonuclease domain in its cytoplasmic side and acts as an ER stress sensor. It is the oldest and most conserved component of the UPR in eukaryotes. Its activation results in the cleavage of its mRNA substrate, HAC1 in yeast and Xbp1 in metazoans, promoting a splicing event that enables translation into a transcription factor which activates the UPR. EIF2AK3, also called PKR-like Endoplasmic Reticulum Kinase (PERK), phosphorylates the alpha subunit of eIF-2, resulting in the downregulation of protein synthesis. It functions as the central regulator of translational control during the UPR pathway. In addition to the eIF-2 alpha subunit, EIF2AK3 also phosphorylates Nrf2, a leucine zipper transcription factor which regulates cellular redox status and promotes cell survival during the UPR.
Pssm-ID: 188873 [Multi-domain] Cd Length: 312 Bit Score: 52.11 E-value: 4.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 108 SDGVVYVTGSYSRVFALDAKTGKRLWTYN---------HRLPDNIRPCCDVVnrgaAIYGDKIYFGTLDARVIALDKNTG 178
Cdd:cd09213 92 EDDVVVVGSKRTSVFALDAKTGKIIKTYRadglpstggSDSDGNSTPGPDEL----QEEEELLYIGRTDYVLQAIDPRSG 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 179 KVVWNKKFGDHSAGYTMtgAPVLIKDKTSGKVLLIHGSSGDEFGVVGQLfaRDPDTGEEVWMRPF----VEGHMGRlnGK 254
Cdd:cd09213 168 KELWNVTYGEYEALTLD--ADELGTSSSSSPLSASFRISENEPVPAVYL--LGLQGGKSLWEHLFdspiVSAFDYS--SK 241
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1524128033 255 DSTPTGDVKAPSWPDDKTTETG-KVEAWSHGGGAPWqsasfdpetntIIVGAGNPGPWNTWARTAKDGNPHDFDSL 329
Cdd:cd09213 242 LTNFEGLIKPIFVFQVHEYASSnSVYIGAHENGQLF-----------ALSSPSKSEDKESAISNILEGENTSPSAL 306
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
106-236 |
1.34e-06 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 51.09 E-value: 1.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 106 IVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRlpdnirpccdvVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVWNKk 185
Cdd:TIGR03300 238 VVDGGQVYAVSYQGRVAALDLRSGRVLWKRDAS-----------SYQGPAVDDNRLYVTDADGVVVALDRRSGSELWKN- 305
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1524128033 186 fgDHSAGYTMTgAPVLIkdktsGKVLLIhgssGDEFGVVGQLfarDPDTGE 236
Cdd:TIGR03300 306 --DELKYRQLT-APAVL-----GGYLVV----GDFEGYLHWL---DRDDGS 341
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
506-629 |
5.13e-06 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 49.16 E-value: 5.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 506 VGTLR----AMDPTTGKLVWEHKehlpLWAGVLA---TKGNLVFTGTGDGFFKAFDAKTGKELWKFQTgsgiVSPPITWE 578
Cdd:TIGR03300 110 VGTEKgeviALDAEDGKELWRAK----LSSEVLSpplVANGLVVVRTNDGRLTALDAATGERLWTYSR----VTPPLTLR 181
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1524128033 579 QDGeqyiGVTVGyGGAVpLWGGDMAELTKPVAQGGSfwvfkiPSWDSKTAQ 629
Cdd:TIGR03300 182 GSA----SPVIA-DGGV-LVGFAGGKLVALDLQTGQ------PLWEQRVAL 220
|
|
| Luminal_IRE1 |
cd09769 |
The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, ... |
108-243 |
5.77e-06 |
|
The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, Inositol-requiring protein 1; The Luminal domain is a dimerization domain present in Inositol-requiring protein 1 (IRE1), a serine/threonine protein kinase (STK) and a type I transmembrane protein that is localized in the endoplasmic reticulum (ER). IRE1, also called Endoplasmic reticulum (ER)-to-nucleus signaling protein (or ERN), is a kinase receptor that also contains an endoribonuclease domain in the cytoplasmic side. It plays roles in the signaling of the unfolded protein response (UPR), which is activated when protein misfolding is detected in the ER in order to decrease the synthesis of new proteins and increase the capacity of the ER to cope with the stress. IRE1 acts as an ER stress sensor and is the oldest and most conserved component of the UPR in eukaryotes. During ER stress, IRE1 dimerizes through its luminal domain and forms oligomers, allowing the kinase domain to undergo trans-autophosphorylation. This leads to a conformational change that stimulates its endoribonuclease activity and results in the cleavage of its mRNA substrate, HAC1 in yeast and Xbp1 in metazoans, promoting a splicing event that enables translation into a transcription factor which activates the UPR. Mammals contain two IRE1 proteins, IRE1alpha (or ERN1) and IRE1beta (or ERN2). IRE1alpha is expressed in all cells and tissues while IRE1beta is found only in intestinal epithelial cells.
Pssm-ID: 188875 [Multi-domain] Cd Length: 295 Bit Score: 48.47 E-value: 5.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 108 SDGVVYvTGSYSRV-FALDAKTGKRL----WTYNHRLPDNIRPCCDVVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVW 182
Cdd:cd09769 87 SDGILY-TGSKQTTwYTVDPRTGEKIqvlgSGGADSNCPESCVDPDDDEQSECSSSSTIYIGRTEYTVTIYDSKTREPIW 165
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1524128033 183 NKKFGDHSAGytmTGAPVLIKDKTSGKVLLIHGSSGDefgvvGQLFARDPDTGEEVWMRPF 243
Cdd:cd09769 166 NVTYSDYTPN---SNDRDLQSQYSKTYDLRYIASSSD-----GSLVTFDRDTGRVLWVQNL 218
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
103-238 |
5.91e-06 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 49.04 E-value: 5.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 103 SQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRlpdnirpccdvVNRGAAIYGDKIYFGTLDARVIALDKNTGKVVW 182
Cdd:COG1520 227 GTPVVDGGVVYAVAYQGRLAALDLRSGRVLWSRDLS-----------SYTGLAVDGNNLYVTDDDGRVWALDRRNGAELW 295
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1524128033 183 -NKKFgdhsaGYTMTGAPVLIKDKtsgkvLLIhgssGDEFGVVGQLfarDPDTGEEV 238
Cdd:COG1520 296 kQDAL-----LYRGLTAPVVLGDY-----VVV----GDFEGYLHWL---SRDDGSLV 335
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
504-575 |
1.88e-05 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 47.23 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 504 DHVGTLRAMDPTTGKLVWE----------HKEHLPLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSP 573
Cdd:PRK11138 76 DRAGLVKALDADTGKEIWSvdlsekdgwfSKNKSALLSGGVTVAGGKVYIGSEKGQVYALNAEDGEVAWQTKVAGEALSR 155
|
..
gi 1524128033 574 PI 575
Cdd:PRK11138 156 PV 157
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
103-198 |
4.84e-05 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 46.08 E-value: 4.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 103 SQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLPdnirpccDVVNRG----AAIYGDKIyFGTLDARVIALDKNTG 178
Cdd:PRK11138 154 SRPVVSDGLVLVHTSNGMLQALNESDGAVKWTVNLDVP-------SLTLRGesapATAFGGAI-VGGDNGRVSAVLMEQG 225
|
90 100
....*....|....*....|
gi 1524128033 179 KVVWNKKFgdhsagYTMTGA 198
Cdd:PRK11138 226 QLIWQQRI------SQPTGA 239
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
99-239 |
5.53e-05 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 45.96 E-value: 5.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 99 RGQeSQAIVSDGVVYVTGSYSRVFALDAKTGKRLWTYNHRLP------DNIRpccDVVNRgAAIYGDKIYFGTLDARVIA 172
Cdd:COG1520 173 RGT-SSPVIVGGAVLVGFANGKLVALDLANGQPLWEQRVAQPrgrtelERLV---DVDGT-PVVDGGVVYAVAYQGRLAA 247
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1524128033 173 LDKNTGKVVWNKKFGdhsaGYTmtgapvlikdktsgkvllihGSSGDEFGVV-----GQLFARDPDTGEEVW 239
Cdd:COG1520 248 LDLRSGRVLWSRDLS----SYT--------------------GLAVDGNNLYvtdddGRVWALDRRNGAELW 295
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
105-136 |
9.09e-05 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 39.82 E-value: 9.09e-05
10 20 30
....*....|....*....|....*....|..
gi 1524128033 105 AIVSDGVVYVTGSYSRVFALDAKTGKRLWTYN 136
Cdd:smart00564 2 VVLSDGTVYVGSTDGTLYALDAKTGEILWTYK 33
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
536-564 |
1.69e-04 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 39.05 E-value: 1.69e-04
10 20
....*....|....*....|....*....
gi 1524128033 536 TKGNLVFTGTGDGFFKAFDAKTGKELWKF 564
Cdd:smart00564 4 LSDGTVYVGSTDGTLYALDAKTGEILWTY 32
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
507-562 |
2.69e-04 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 43.65 E-value: 2.69e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHLP---LW-AGVLATKGNLVFTGTGDGFFKAFDAKTGKELW 562
Cdd:COG1520 147 GRVYALDAATGERLWSYQRPVPaltLRgTSSPVIVGGAVLVGFANGKLVALDLANGQPLW 206
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
507-562 |
2.75e-04 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 42.78 E-value: 2.75e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHLPLWA----GVLATKGNLVFTGTGDGFFKAFDAKTGKELW 562
Cdd:pfam13360 83 GSLIALDAADGRRLWSYQRSGEPLAlrssGSPAVVGDTVVAGFSSGKLVALDPATGKVRW 142
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
506-569 |
7.97e-04 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 41.62 E-value: 7.97e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1524128033 506 VGTLRAMDPTTGKLVWEhkehLPLWAGVLATK---GNLVFTGTGDGFFKAFDAKTGKELWKFQTGSG 569
Cdd:pfam13360 42 GGQLVALDAATGKLLWR----QTLSGEVLGAPlvaGGRVFVVAGDGSLIALDAADGRRLWSYQRSGE 104
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
507-598 |
8.85e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 42.21 E-value: 8.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEH-LPLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSpPITWEQDGeQYI 585
Cdd:COG2319 310 GTVRLWDLATGKLLRTLTGHtGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVT-SVAFSPDG-RTL 387
|
90
....*....|...
gi 1524128033 586 gVTVGYGGAVPLW 598
Cdd:COG2319 388 -ASGSADGTVRLW 399
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
386-568 |
1.97e-03 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 40.78 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 386 NGFFYVVDRNNGklqnafpfvdniTWAshIDLKTGRPVENEgqrpakplpgETKGKPVEVSPP-------FLGGKNWNPM 458
Cdd:cd10276 38 GDMVYAADANGQ------------VSA--FNATTGKIIWET----------SLSGKGFLGGTPavgngkiFVGTESGYLY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 459 AYSQDTGlfyipgnqwkEEYWTEEVN---------YKKGSAYLGmgfrikrmydDHVGTLRAMDPTTGKLVWEHKEHLP- 528
Cdd:cd10276 94 ALDAKDG----------SELWRTEVSdsqllspptYADGKIYVG----------TGDGRLYYCNAETGKVVWNRTSTAPe 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1524128033 529 --LWAG--VLATKGNlVFTGTGDGFFKAFDAKTGKELWKFQTGS 568
Cdd:cd10276 154 lsLRGGaaPVGAYDV-VFVGDGNGTVVALNTGTGVDIWEFSVSE 196
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
159-182 |
2.98e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 35.63 E-value: 2.98e-03
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
107-219 |
3.00e-03 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 40.30 E-value: 3.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 107 VSDGVVYVTGSYSRVFALDAKTGKRLWTyNHRLpdnirpccdvVNR---GAAIYGDKIYFGTLDARVIALDKNTGKVVWN 183
Cdd:TIGR03300 277 VDDNRLYVTDADGVVVALDRRSGSELWK-NDEL----------KYRqltAPAVLGGYLVVGDFEGYLHWLDRDDGSFVAR 345
|
90 100 110
....*....|....*....|....*....|....*.
gi 1524128033 184 KKFGdhsaGYTMTGAPVLIKDKtsgkvLLIHGSSGD 219
Cdd:TIGR03300 346 LKTD----GSGIASPPVVVGDG-----LLVQTRDGD 372
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
535-595 |
3.00e-03 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 40.18 E-value: 3.00e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1524128033 535 ATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSppitweqdgeqyiGVTVGYGGAV 595
Cdd:COG1520 54 AVAGDRVYAADADGRVAALDAATGKELWRVDLGEPLSG-------------GVGADGGLVV 101
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
167-346 |
3.24e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 39.69 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 167 DARVIALDKNTGKVVWNKKFGDHSAGytmtGAPVlikdktSGKVLLIHGSSgdefgvvGQLFARDPDTGEEVWMRPFVEG 246
Cdd:pfam13360 2 DGVVTALDAATGAELWRVDLETGLGG----GVAV------DGGRLFVATGG-------GQLVALDAATGKLLWRQTLSGE 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 247 hmgrlNGKDSTPTGDVKAPSWPDDK----TTETGKVeAWSHGGGAPW----QSASFDPETNTIIVGagnpgpwntwarta 318
Cdd:pfam13360 65 -----VLGAPLVAGGRVFVVAGDGSlialDAADGRR-LWSYQRSGEPlalrSSGSPAVVGDTVVAG-------------- 124
|
170 180
....*....|....*....|....*....
gi 1524128033 319 kdgnphdfdslYTSGQV-GVDPSTGEVKW 346
Cdd:pfam13360 125 -----------FSSGKLvALDPATGKVRW 142
|
|
| PA2928_fam |
NF041516 |
PA2928 family protein; This family is named for the locus PA2928 of Pseudomonas aeroginosa ... |
107-399 |
4.39e-03 |
|
PA2928 family protein; This family is named for the locus PA2928 of Pseudomonas aeroginosa PAO1, as the family member most frequently cited in the literature, although PA2928 itself is significantly shorter at the N-terminus than most other members of this family, and is probably non-functional. WP_017001489.1 represents an intact equivalent to the PA2928 pseudogene.
Pssm-ID: 469402 [Multi-domain] Cd Length: 345 Bit Score: 39.66 E-value: 4.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 107 VSDGVVYVTgSYSRVFALDAKTGKRLWTynHRLPDNIrpccdvvNRGAAIYG---DKIYFGTlDARVIALDKNTGKVV-- 181
Cdd:NF041516 58 MSNGITSGM-SQFRLAAVDLATGEKLWD--KKLSDEL-------SWEAYLLGatdRYLYVAT-DKGLYVLDLATGKVVad 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 182 ---WNKKFGDHSAGY-TMTGAPVLIkdkTSGKVLLIHGSSgdefgvvGQLFARDPDTGEEVwmrPFVEGHMGRLNGKDST 257
Cdd:NF041516 127 ekeLEGLGPALKDNLsAARAAYAYD---DDNRALYFYGLD-------GRYYQIDLDTLTAT---PADPATAPTYAGLLFA 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 258 PTGDVKAPSWPDDKTT----ETGKVEAWSHGGGAPWQSA----SFDPETNTIIVGA---GNPGPWNTWARTAKDGNP--- 323
Cdd:NF041516 194 EEAAKGRPATFLSDKEeaalEDERVALRERPRGALYGGVlvrvGGDGDLTPLGDTVfldGGFLLDPTTLEGAADGHVlvv 273
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1524128033 324 HDfDSLYTSGQV---GVDPSTGEVKWfyqHTPNDAWDFSgnnelvlFDYKGKDGKVVKATGHADrNGFFYVVDRNNGKL 399
Cdd:NF041516 274 HK-RTVNDDANLllsAVDLETGKVTW---TLPLGYSSPS-------RAFTLPDGLTLLGAGNPE-GGDLLKIDLKDGKL 340
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
507-598 |
4.49e-03 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 39.89 E-value: 4.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHL-PLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSpPITWEQDGeQYI 585
Cdd:COG2319 268 GTVRLWDLATGELLRTLTGHSgGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVR-SVAFSPDG-KTL 345
|
90
....*....|...
gi 1524128033 586 gVTVGYGGAVPLW 598
Cdd:COG2319 346 -ASGSDDGTVRLW 357
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
507-598 |
5.30e-03 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 39.51 E-value: 5.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEH-LPLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSpPITWEQDGeQYI 585
Cdd:COG2319 184 GTVRLWDLATGKLLRTLTGHtGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVR-SVAFSPDG-RLL 261
|
90
....*....|...
gi 1524128033 586 gVTVGYGGAVPLW 598
Cdd:COG2319 262 -ASGSADGTVRLW 273
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
110-136 |
5.39e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 34.86 E-value: 5.39e-03
10 20
....*....|....*....|....*..
gi 1524128033 110 GVVYVTGSYSRVFALDAKTGKRLWTYN 136
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFK 27
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
157-183 |
7.09e-03 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 34.43 E-value: 7.09e-03
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
507-598 |
7.24e-03 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 39.12 E-value: 7.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHL-PLWAGVLATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSpPITWEQDGeQYI 585
Cdd:COG2319 100 GTVRLWDLATGLLLRTLTGHTgAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVT-SVAFSPDG-KLL 177
|
90
....*....|...
gi 1524128033 586 gVTVGYGGAVPLW 598
Cdd:COG2319 178 -ASGSDDGTVRLW 189
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
507-563 |
7.37e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 38.54 E-value: 7.37e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1524128033 507 GTLRAMDPTTGKLVWEHKEHLPLwaGVLATkGNLVFTGTGDGFFKAFDAKTGKELWK 563
Cdd:pfam13360 179 GRLVAFDAATGRRLWTREISGPN--GPILD-GDLLYVVSDDGELYALDRATGAVVWK 232
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
535-592 |
9.54e-03 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 38.76 E-value: 9.54e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1524128033 535 ATKGNLVFTGTGDGFFKAFDAKTGKELWKFQTGSGIVSppitweqdgeqyiGVTVGYG 592
Cdd:TIGR03300 62 AVAGGKVYAADADGTVAALDAETGKRLWRVDLDERLSG-------------GVGADGG 106
|
|
| |
