|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
364-546 |
4.22e-34 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 129.79 E-value: 4.22e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 364 KSINGLVNKVNASNIKNIIPELFAENLIRG--RGLFCRSCMKSQMASPGFTDVFAALVAVINAKFPEVAELLLKRVVLQL 441
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKnlRKYILELIFEKAVEEPNFIPAYARLCALLNAKNPDFGSLLLERLQEEF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 442 KR---AYKRNDKPQLLAAVKFIAHLVNQQVAEEIIALELVTILLGDPT-------DDSVEVAVGFVTECGAML-QDVSPR 510
Cdd:smart00543 82 EKgleSEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLKELLNDLTkldpprsDFSVECLLSLLPTCGKDLeREKSPK 161
|
170 180 190
....*....|....*....|....*....|....*....
gi 15220892 511 GLNGIFERFRGILHE---GEIDKRVQYLIESLFATRKAK 546
Cdd:smart00543 162 LLDEILERLQDYLLKkdkTELSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
650-756 |
3.06e-30 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 115.45 E-value: 3.06e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 650 LRRTIYLTIMSSV---DFEEAGHKLLKIKLePGQEMELCIMLLECCSQE-RTYLRYYGLLGQRFCMINKIHQENFEKCFV 725
Cdd:pfam02847 1 LKRKIFLILEEYLssgDYDEAARCLLKLGL-PSQHHEVVKVLIECALEEsKTYREFYGLLLERLCEFNLISTKQFEKGFW 79
|
90 100 110
....*....|....*....|....*....|....
gi 15220892 726 QQYSMIHRLET---NKLRNVAKFFAHLLGTDALP 756
Cdd:pfam02847 80 RVLEDLEDLELdipNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
650-756 |
5.85e-28 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 108.87 E-value: 5.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 650 LRRTIYLTIMSSV---DFEEAGHKLLKIKLePGQEMELCIMLLECCSQE-RTYLRYYGLLGQRFCMINKIHQENFEKCFV 725
Cdd:smart00544 1 LKKKIFLIIEEYLssgDTDEAVHCLLELKL-PEQHHEVVKVLLTCALEEkRTYREMYSVLLSRLCQANVISTKQFEKGFW 79
|
90 100 110
....*....|....*....|....*....|....
gi 15220892 726 QQYSMIHRLET---NKLRNVAKFFAHLLGTDALP 756
Cdd:smart00544 80 RLLEDIEDLELdipNAWRNLAEFVARLISDGILP 113
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
33-283 |
1.78e-11 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 68.01 E-value: 1.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 33 TETDDVARRVRVSDDEDRKSSRRDLEIGGTVADGEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRiEVDS 112
Cdd:PRK12678 69 TPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAAR-KAGE 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 113 DGDGERRVNKGRNTDRVRADTSSDEEDDlkgnkKEPMEvdddygrrgrrrspkvmEKQGRERSHRGSRviadKPSDEEDD 192
Cdd:PRK12678 148 GGEQPATEARADAAERTEEEERDERRRR-----GDRED-----------------RQAEAERGERGRR----EERGRDGD 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 193 RQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGhENGSRRRESERKDRSRRDDG 272
Cdd:PRK12678 202 DRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGG-RRGRRFRDRDRRGRRGGDGG 280
|
250
....*....|.
gi 15220892 273 VRDEKERRHND 283
Cdd:PRK12678 281 NEREPELREDD 291
|
|
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
363-544 |
6.18e-09 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 56.99 E-value: 6.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 363 RKSINGLVNKVNASNIKNIIPEL--FAENLIRGRGLFCRSCMKSQMASPGFTDVFAALVAVINAKFP-EVAELLLKRVVL 439
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELlkLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLRNPtDFGIHLLNRLQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 440 QLKRAYKRNDKPQL-----LAAVKFIAHLVNQQVAEEIIALELVTILLGDPT-------DDSVEVAVGFVTECGAML-QD 506
Cdd:pfam02854 81 EFEKRFELEENEQGnrrrrLGLVRFLGELYKFGLLTEKILFECLKELLSSLTkedlkrdLFNLECLLTLLTTIGKLLeNE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 15220892 507 VSPRGLNGIFERFRGIL---HEGEIDKRVQYLIESLFATRK 544
Cdd:pfam02854 161 KLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRK 201
|
|
| U2AF_lg |
TIGR01642 |
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ... |
184-336 |
2.24e-07 |
|
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.
Pssm-ID: 273727 [Multi-domain] Cd Length: 509 Bit Score: 54.51 E-value: 2.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 184 DKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRReser 263
Cdd:TIGR01642 2 DEEPDREREKSRGRDRDRSSERPRRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRSLRYSSVRRSRDR---- 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15220892 264 kDRSRRDDGVRDEKERRHNdkyDDSQRDKLRKEDSRKREEKKIevPKPKLAELNPSENNAMALGKTGGVYIPP 336
Cdd:TIGR01642 78 -PRRRSRSVRSIEQHRRRL---RDRSPSNQWRKDDKKRSLWDI--KPPGYELVTADQAKASQVFSVPGTAPRP 144
|
|
| EIF4E-T |
pfam10477 |
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; EIF4E-T is the transporter ... |
186-317 |
3.25e-04 |
|
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; EIF4E-T is the transporter protein for shuttling the mRNA cap-binding protein EIF4E protein, targeting it for nuclear import. EIF4E-T contains several key binding domains including two functional leucine-rich NESs (nuclear export signals) between residues 438-447 and 613-638 in the human protein. The other two binding domains are an EIF4E-binding site, between residues 27-42 in Q9EST3, and a bipartite NLS (nuclear localization signals) between 194-211, and these lie in family EIF4E-T_N. EIF4E is the eukaryotic translation initiation factor 4E that is the rate-limiting factor for cap-dependent translation initiation.
Pssm-ID: 371079 Cd Length: 646 Bit Score: 44.23 E-value: 3.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 186 PSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRE--------RDLTDGHENGSR 257
Cdd:pfam10477 140 PRDYKNQPADEARIEREKDRSPNGSGSSRQDEEDQRNNQQNLRTFSGRHNERGRDGDRRSkrnrrtfgRFQYDGKKPVDR 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 258 RRESERKDRSRRDDGVRDEKERRHNDKYDD-----------SQR---------DKLRKEDSRKREEKKIEVPKPKLAELN 317
Cdd:pfam10477 220 GRRISNKDKFSFQDRGKRYNSRRRNDSYTEeepewfsagptSQHetielhgfdDKEEDNKRRSRTRVKTESFKELDLECN 299
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
364-546 |
4.22e-34 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 129.79 E-value: 4.22e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 364 KSINGLVNKVNASNIKNIIPELFAENLIRG--RGLFCRSCMKSQMASPGFTDVFAALVAVINAKFPEVAELLLKRVVLQL 441
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKnlRKYILELIFEKAVEEPNFIPAYARLCALLNAKNPDFGSLLLERLQEEF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 442 KR---AYKRNDKPQLLAAVKFIAHLVNQQVAEEIIALELVTILLGDPT-------DDSVEVAVGFVTECGAML-QDVSPR 510
Cdd:smart00543 82 EKgleSEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLKELLNDLTkldpprsDFSVECLLSLLPTCGKDLeREKSPK 161
|
170 180 190
....*....|....*....|....*....|....*....
gi 15220892 511 GLNGIFERFRGILHE---GEIDKRVQYLIESLFATRKAK 546
Cdd:smart00543 162 LLDEILERLQDYLLKkdkTELSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
650-756 |
3.06e-30 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 115.45 E-value: 3.06e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 650 LRRTIYLTIMSSV---DFEEAGHKLLKIKLePGQEMELCIMLLECCSQE-RTYLRYYGLLGQRFCMINKIHQENFEKCFV 725
Cdd:pfam02847 1 LKRKIFLILEEYLssgDYDEAARCLLKLGL-PSQHHEVVKVLIECALEEsKTYREFYGLLLERLCEFNLISTKQFEKGFW 79
|
90 100 110
....*....|....*....|....*....|....
gi 15220892 726 QQYSMIHRLET---NKLRNVAKFFAHLLGTDALP 756
Cdd:pfam02847 80 RVLEDLEDLELdipNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
650-756 |
5.85e-28 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 108.87 E-value: 5.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 650 LRRTIYLTIMSSV---DFEEAGHKLLKIKLePGQEMELCIMLLECCSQE-RTYLRYYGLLGQRFCMINKIHQENFEKCFV 725
Cdd:smart00544 1 LKKKIFLIIEEYLssgDTDEAVHCLLELKL-PEQHHEVVKVLLTCALEEkRTYREMYSVLLSRLCQANVISTKQFEKGFW 79
|
90 100 110
....*....|....*....|....*....|....
gi 15220892 726 QQYSMIHRLET---NKLRNVAKFFAHLLGTDALP 756
Cdd:smart00544 80 RLLEDIEDLELdipNAWRNLAEFVARLISDGILP 113
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
33-283 |
1.78e-11 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 68.01 E-value: 1.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 33 TETDDVARRVRVSDDEDRKSSRRDLEIGGTVADGEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRiEVDS 112
Cdd:PRK12678 69 TPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAAR-KAGE 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 113 DGDGERRVNKGRNTDRVRADTSSDEEDDlkgnkKEPMEvdddygrrgrrrspkvmEKQGRERSHRGSRviadKPSDEEDD 192
Cdd:PRK12678 148 GGEQPATEARADAAERTEEEERDERRRR-----GDRED-----------------RQAEAERGERGRR----EERGRDGD 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 193 RQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGhENGSRRRESERKDRSRRDDG 272
Cdd:PRK12678 202 DRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGG-RRGRRFRDRDRRGRRGGDGG 280
|
250
....*....|.
gi 15220892 273 VRDEKERRHND 283
Cdd:PRK12678 281 NEREPELREDD 291
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
60-297 |
3.56e-11 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 66.85 E-value: 3.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 60 GGTVADGEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRIevdsdgdGERRVNKGRNTDRVRADTSSDEED 139
Cdd:PRK12678 61 GGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAAR-------AAAAAAAEAASAPEAAQARERRER 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 140 DLKGNKKEPMEVDDDYGRRGRRRSPKVMEKQGRERSHRGSRVIADKPSDEEDDRQRsRGGRRESQRKRRDHRASDDDEEG 219
Cdd:PRK12678 134 GEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGE-RGRREERGRDGDDRDRRDRREQG 212
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15220892 220 EIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRRESERKDRSRRDDGVRDEKERRHNDKYDDSQRDKLRKED 297
Cdd:PRK12678 213 DRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNEREPELRED 290
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
67-301 |
1.21e-09 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 61.84 E-value: 1.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 67 EGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRIEVDSDgdgeRRVNKGRNTDRVRADTSSDEEDdlkgnkk 146
Cdd:PRK12678 56 KEARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKA----EAAPAARAAAAAAAEAASAPEA------- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 147 EPMEVDDDYGRRGRRRSPKVMEKQGRERSHRGSRVIADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEirsERR 226
Cdd:PRK12678 125 AQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGR---DGD 201
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15220892 227 GKEKNDRGSEGLLKRDRRERDLTDGHENGSRRReserkDRSRRDDGVRDEKERRHNDKYDDSQRDKLRKEDSRKR 301
Cdd:PRK12678 202 DRDRRDRREQGDRREERGRRDGGDRRGRRRRRD-----RRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDR 271
|
|
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
363-544 |
6.18e-09 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 56.99 E-value: 6.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 363 RKSINGLVNKVNASNIKNIIPEL--FAENLIRGRGLFCRSCMKSQMASPGFTDVFAALVAVINAKFP-EVAELLLKRVVL 439
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELlkLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLRNPtDFGIHLLNRLQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 440 QLKRAYKRNDKPQL-----LAAVKFIAHLVNQQVAEEIIALELVTILLGDPT-------DDSVEVAVGFVTECGAML-QD 506
Cdd:pfam02854 81 EFEKRFELEENEQGnrrrrLGLVRFLGELYKFGLLTEKILFECLKELLSSLTkedlkrdLFNLECLLTLLTTIGKLLeNE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 15220892 507 VSPRGLNGIFERFRGIL---HEGEIDKRVQYLIESLFATRK 544
Cdd:pfam02854 161 KLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRK 201
|
|
| U2AF_lg |
TIGR01642 |
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ... |
184-336 |
2.24e-07 |
|
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.
Pssm-ID: 273727 [Multi-domain] Cd Length: 509 Bit Score: 54.51 E-value: 2.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 184 DKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRReser 263
Cdd:TIGR01642 2 DEEPDREREKSRGRDRDRSSERPRRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRSLRYSSVRRSRDR---- 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15220892 264 kDRSRRDDGVRDEKERRHNdkyDDSQRDKLRKEDSRKREEKKIevPKPKLAELNPSENNAMALGKTGGVYIPP 336
Cdd:TIGR01642 78 -PRRRSRSVRSIEQHRRRL---RDRSPSNQWRKDDKKRSLWDI--KPPGYELVTADQAKASQVFSVPGTAPRP 144
|
|
| SF-CC1 |
TIGR01622 |
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ... |
193-306 |
5.05e-07 |
|
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.
Pssm-ID: 273721 [Multi-domain] Cd Length: 494 Bit Score: 53.38 E-value: 5.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 193 RQRSRGGRRESQRKRRDHRASDDDEEGE---IRSERRGKEKN-DRGSEGLLKRDRRERDltdgHENGSRRRESERKDRSR 268
Cdd:TIGR01622 3 RDRERERLRDSSSAGDRDRRRDKGRERSrdrSRDRERSRSRRrDRHRDRDYYRGRERRS----RSRRPNRRYRPREKRRR 78
|
90 100 110
....*....|....*....|....*....|....*....
gi 15220892 269 RDDGVRDEKE-RRHNDKYDDSQRDKLRKEDSRKREEKKI 306
Cdd:TIGR01622 79 RGDSYRRRRDdRRSRREKPRARDGTPEPLTEDERDRRTV 117
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
183-303 |
6.06e-07 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 53.37 E-value: 6.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 183 ADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDltDGHENGSRRRESE 262
Cdd:PRK12678 121 APEAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEA--ERGERGRREERGR 198
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 15220892 263 RKDRSRRDDGvRDEKERRHNDKYDDSQRDKLRKEDSRKREE 303
Cdd:PRK12678 199 DGDDRDRRDR-REQGDRREERGRRDGGDRRGRRRRRDRRDA 238
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
26-217 |
5.89e-06 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 49.90 E-value: 5.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 26 PDVRRSRTETDDVARRVRVSDDEDRKSSRRDLEiggtvADGEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRG 105
Cdd:PRK12678 136 AARRGAARKAGEGGEQPATEARADAAERTEEEE-----RDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRRE 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 106 KRIEVDSDGDGERRVNKGRNTDRVRADTSSDEEDDLKGnkkePMEVDDDygrrgrrrspkvmEKQGRERSHRGsrviadk 185
Cdd:PRK12678 211 QGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRG----DRDGDDG-------------EGRGGRRGRRF------- 266
|
170 180 190
....*....|....*....|....*....|..
gi 15220892 186 psdeeDDRQRsRGGRRESQRKRRDHRASDDDE 217
Cdd:PRK12678 267 -----RDRDR-RGRRGGDGGNEREPELREDDV 292
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
67-351 |
1.73e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.98 E-value: 1.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 67 EGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRG---KRIEVDSDGDGERRVNKGRNTDRvrADTSSDEEDDLKg 143
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaeeARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAEELK- 1626
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 144 nKKEPMEVDDDYGRRGRRRSPKVMEKQGRERSHRGSRVIADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRS 223
Cdd:PTZ00121 1627 -KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 224 ERRGKEKNDRGSEGLLKRDRRER-----DLTDGHENGSRRRESERKDRSRRDDGVRDEKERRHNDKYDDSQRDKLRKEDS 298
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENkikaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 15220892 299 RKREEKKIEVPKPKLAELNPSENNAMALGKTGGVYIPPFK--LARMMKEVEDKSS 351
Cdd:PTZ00121 1786 DEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKemEDSAIKEVADSKN 1840
|
|
| SF-CC1 |
TIGR01622 |
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ... |
169-293 |
3.86e-05 |
|
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.
Pssm-ID: 273721 [Multi-domain] Cd Length: 494 Bit Score: 47.22 E-value: 3.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 169 KQGRERS-HRGSRVIADKP--SDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRE 245
Cdd:TIGR01622 2 YRDRERErLRDSSSAGDRDrrRDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRRRRGD 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 15220892 246 rdltdghengsrRRESERKDRSRRDDGVRDekERRHNDKYDDSQRDKL 293
Cdd:TIGR01622 82 ------------SYRRRRDDRRSRREKPRA--RDGTPEPLTEDERDRR 115
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
27-315 |
4.68e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 4.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 27 DVRRSrtETDDVARRVRVSDDEDRKSSRRDLEIGGTVADGegRRGDKVRRKETSDDEELARRSRKDRKeANSGSEDDRGK 106
Cdd:PTZ00121 1126 DARKA--EEARKAEDARKAEEARKAEDAKRVEIARKAEDA--RKAEEARKAEDAKKAEAARKAEEVRK-AEELRKAEDAR 1200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 107 RIEVDSDGDGERRVNKGRNTDRVRADTSSDEEDDLKGNKKEPMEVDDDygrRGRRRSPKVMEKQGRERSHRGSRVIADKP 186
Cdd:PTZ00121 1201 KAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEE---RNNEEIRKFEEARMAHFARRQAAIKAEEA 1277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 187 SDEEDDRQRSRGGRRESQRKRRDHRASDddeegEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRRESERKDR 266
Cdd:PTZ00121 1278 RKADELKKAEEKKKADEAKKAEEKKKAD-----EAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 15220892 267 SRRDDGVRDEKERRHNDKYDDSQRDKLRKEDSRKREEKKIEVPKPKLAE 315
Cdd:PTZ00121 1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
67-320 |
4.80e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 4.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 67 EGRRGDKVRRK--ETSDDEELARRSRKDRKEANSGSEDDRGKRIEVDSDGDGERRVNKGRNTDRVR-------ADTSSDE 137
Cdd:PTZ00121 1481 EAKKADEAKKKaeEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKkadelkkAEELKKA 1560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 138 EDDLKGNKKEPMEVDDDYGRRGRRRSPKVMEKQGRE---RSHRGSRVIADKPSDEEDDRQRSRGGRRESQRKRRDHRASD 214
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEvmkLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 215 DDEEGEIRSERRGKEKndrgSEGLLKRDRRERDLTDGHENGSRRRESERKDRSRRDDGVRDEKERRHNDKYDDSQRDKLR 294
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAE----EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716
|
250 260
....*....|....*....|....*.
gi 15220892 295 KEDSRKREEkkiEVPKPKLAELNPSE 320
Cdd:PTZ00121 1717 KAEELKKAE---EENKIKAEEAKKEA 1739
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
61-309 |
1.01e-04 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 46.14 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 61 GTVADGEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRiEVDSDGDGERrvnKGRNTDRVRADtssDEEDD 140
Cdd:TIGR00927 633 GDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGEN-ESEGEIPAER---KGEQEGEGEIE---AKEAD 705
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 141 LKGnkkepmEVDDDYGRRGRRRSPKVMEKQGRERSHRGSRVIADkpsDEEDDRQRSRGGRRESQRKRRDHRA------SD 214
Cdd:TIGR00927 706 HKG------ETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVED---EGEGEAEGKHEVETEGDRKETEHEGeteaegKE 776
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 215 DDEEGEIRSERRGKEKNDRGSEGLLKRDRRER----------------DLTDGHENGSRRRESERKDRSRRDD-GVRDEK 277
Cdd:TIGR00927 777 DEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEagekdehegqsetqadDTEVKDETGEQELNAENQGEAKQDEkGVDGGG 856
|
250 260 270
....*....|....*....|....*....|....*..
gi 15220892 278 ERRHNDKYD-----DSQRDKLRKEDSRKREEKKIEVP 309
Cdd:TIGR00927 857 GSDGGDSEEeeeeeEEEEEEEEEEEEEEEEEEENEEP 893
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
172-304 |
1.15e-04 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 46.05 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 172 RERSHRGSRVIADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEiRSERRGKEKNDRGSEGLLKRDR-RERDLTD 250
Cdd:PRK12678 87 ARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGE-AARRGAARKAGEGGEQPATEARaDAAERTE 165
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 15220892 251 GHENGSRRRESERKDRSRRDD-GVRDEKERRHNDKYDDSQRDKLRKEDSRKREEK 304
Cdd:PRK12678 166 EEERDERRRRGDREDRQAEAErGERGRREERGRDGDDRDRRDRREQGDRREERGR 220
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
40-315 |
1.42e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.90 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 40 RRVRVSDDEDRKSSRRDLEIGGTvadgEGRRGDKVRRKETSDDEElARRSRKDRKEANSGSEDDRGKRIEVdsdgdgeRR 119
Cdd:PTZ00121 1062 AKAHVGQDEGLKPSYKDFDFDAK----EDNRADEATEEAFGKAEE-AKKTETGKAEEARKAEEAKKKAEDA-------RK 1129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 120 VNKGRNTDRVR-ADTSSDEEDDLKGNKKEPMEvdddyGRRGRRRSPKVMEKQGRERSHRGSRV-IADKPSDEEDDRQRSR 197
Cdd:PTZ00121 1130 AEEARKAEDARkAEEARKAEDAKRVEIARKAE-----DARKAEEARKAEDAKKAEAARKAEEVrKAEELRKAEDARKAEA 1204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 198 GGRRESQRKRRDHRASDDD---EEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRRESERKDRSRRDDGVR 274
Cdd:PTZ00121 1205 ARKAEEERKAEEARKAEDAkkaEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK 1284
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 15220892 275 DEKERRHNDKYDDSQRDKLRKEDSRKREEKKIEVPKPKLAE 315
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAE 1325
|
|
| EIF4E-T |
pfam10477 |
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; EIF4E-T is the transporter ... |
186-317 |
3.25e-04 |
|
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; EIF4E-T is the transporter protein for shuttling the mRNA cap-binding protein EIF4E protein, targeting it for nuclear import. EIF4E-T contains several key binding domains including two functional leucine-rich NESs (nuclear export signals) between residues 438-447 and 613-638 in the human protein. The other two binding domains are an EIF4E-binding site, between residues 27-42 in Q9EST3, and a bipartite NLS (nuclear localization signals) between 194-211, and these lie in family EIF4E-T_N. EIF4E is the eukaryotic translation initiation factor 4E that is the rate-limiting factor for cap-dependent translation initiation.
Pssm-ID: 371079 Cd Length: 646 Bit Score: 44.23 E-value: 3.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 186 PSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRE--------RDLTDGHENGSR 257
Cdd:pfam10477 140 PRDYKNQPADEARIEREKDRSPNGSGSSRQDEEDQRNNQQNLRTFSGRHNERGRDGDRRSkrnrrtfgRFQYDGKKPVDR 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 258 RRESERKDRSRRDDGVRDEKERRHNDKYDD-----------SQR---------DKLRKEDSRKREEKKIEVPKPKLAELN 317
Cdd:pfam10477 220 GRRISNKDKFSFQDRGKRYNSRRRNDSYTEeepewfsagptSQHetielhgfdDKEEDNKRRSRTRVKTESFKELDLECN 299
|
|
| DMP1 |
pfam07263 |
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix ... |
45-304 |
4.30e-04 |
|
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth specific protein initially identified from mineralized dentin. DMP1 is primarily localized in the nuclear compartment of undifferentiated osteoblasts. In the nucleus, DMP1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the early phase of osteoblast maturation, Ca(2+) surges into the nucleus from the cytoplasm, triggering the phosphorylation of DMP1 by a nuclear isoform of casein kinase II. This phosphorylated DMP1 is then exported out into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP1 is a unique molecule that initiates osteoblast differentiation by transcription in the nucleus and orchestrates mineralized matrix formation extracellularly, at later stages of osteoblast maturation. The DMP1 gene has been found to be ectopically expressed in lung cancer although the reason for this is unknown.
Pssm-ID: 462128 [Multi-domain] Cd Length: 519 Bit Score: 43.76 E-value: 4.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 45 SDDED-----RKSSRRDleiGGTVADGEGRRGDKVRRKETSDDEELARR-SRKDRKEANSGSEDDRGKRIevDSDGDGER 118
Cdd:pfam07263 216 SDDPDsirseRGNSRMS---SASVKSKESKGDSEQASTQDSGDSQSVEYpSRKFFRKSRISEEDDRGELD--DSNTMEEV 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 119 RVNKGRNTDRVRADTSSDEEDdlkgNKKEPMEvdDDYGRRGRRRSPKVMEKQGRERSHRGSRVIADKPSDEEDDRQRSRG 198
Cdd:pfam07263 291 KSDSTESTSSKEAGLSQSRED----SKSESQE--DSEESQSQEDSQNSQDPSSESSQEADLPSQESSSESQEEVVSESRG 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 199 GRRE-SQRKRRDHRASDDDEEGEI------RSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRRESE-RKDRSRRD 270
Cdd:pfam07263 365 DNPDnTSSSEEDQEDSDSSEEDSLstfsssESESREEQADSESNESLRSSEESPESSEDENSSSQEGLQSHsASTESQSE 444
|
250 260 270
....*....|....*....|....*....|....
gi 15220892 271 DGVRDEKERRHNDKYDDSQRDKLRKEDSRKREEK 304
Cdd:pfam07263 445 ESQSEQDSQSEEDDESDSQDSSRSKEDSNSTEST 478
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
183-305 |
5.81e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.87 E-value: 5.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 183 ADKPSDEEDDRQRSRGGRRES-QRKRRDhrasdddeegeiRSERRGKEKNDRGSEGllkRDRRErdltdghENGSRRRES 261
Cdd:PRK10811 589 QEQPAPKAEAKPERQQDRRKPrQNNRRD------------RNERRDTRDNRTRREG---RENRE-------ENRRNRRQA 646
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 15220892 262 ERKDRSRRDDGVRDEKERRhndKYDDSQRDKLRKEDSRKREEKK 305
Cdd:PRK10811 647 QQQTAETRESQQAEVTEKA---RTQDEQQQAPRRERQRRRNDEK 687
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
185-279 |
6.01e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.87 E-value: 6.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 185 KPSDEEDDRQRSRGGRRESQRK----RRDHRASDDDEEG-EIRSERRgKEKNDRGSEGLLKRDRRERDLTDGHENGSRRR 259
Cdd:PRK10811 594 PKAEAKPERQQDRRKPRQNNRRdrneRRDTRDNRTRREGrENREENR-RNRRQAQQQTAETRESQQAEVTEKARTQDEQQ 672
|
90 100
....*....|....*....|
gi 15220892 260 ESERKDRSRRddgvRDEKER 279
Cdd:PRK10811 673 QAPRRERQRR----RNDEKR 688
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
39-356 |
8.44e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.21 E-value: 8.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 39 ARRVRVSDDEDRKSSRRDLEIGGTVADgEGRRGDKVRRKEtsddEELARRSRKDRKEANSGSEDDRGKRIEVDSDGDGER 118
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAE-EAKKADEAKKKA----EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 119 RVNKGRNTDRVRADTSSDEEDDLKGNKKEPMEVDDdygrrgrrrspkvMEKQGRERSHRgsrviADKPSDEEDDRQRSRG 198
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE-------------AKKKAEEDKKK-----ADELKKAAAAKKKADE 1422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 199 GRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRRESERKDRSRRDDGVRDEKE 278
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15220892 279 RRHNDKYDDSQRDKLRKEDSRKREEKKIEvPKPKLAELNPSENNAMAlgktggvyiPPFKLARMMKEVEDKSSVEYQR 356
Cdd:PTZ00121 1503 KKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKKKA---------DELKKAEELKKAEEKKKAEEAK 1570
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
168-307 |
8.58e-04 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 42.97 E-value: 8.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 168 EKQGRERSHRGSRVIADKPSDEEDDRQRSRG------GRRESQRKRRDHRASdddeegeiRSERRGKEKNDRGSEGLLKR 241
Cdd:PRK12678 84 AAAARQAEQPAAEAAAAKAEAAPAARAAAAAaaeaasAPEAAQARERRERGE--------AARRGAARKAGEGGEQPATE 155
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15220892 242 DR-RERDLTDGHENGSRRRESERKDRSRRDDGVRDEKERRHNDKYDDSQRDKLRKEDSRKREEKKIE 307
Cdd:PRK12678 156 ARaDAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRD 222
|
|
| EIF4E-T |
pfam10477 |
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; EIF4E-T is the transporter ... |
109-323 |
1.66e-03 |
|
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; EIF4E-T is the transporter protein for shuttling the mRNA cap-binding protein EIF4E protein, targeting it for nuclear import. EIF4E-T contains several key binding domains including two functional leucine-rich NESs (nuclear export signals) between residues 438-447 and 613-638 in the human protein. The other two binding domains are an EIF4E-binding site, between residues 27-42 in Q9EST3, and a bipartite NLS (nuclear localization signals) between 194-211, and these lie in family EIF4E-T_N. EIF4E is the eukaryotic translation initiation factor 4E that is the rate-limiting factor for cap-dependent translation initiation.
Pssm-ID: 371079 Cd Length: 646 Bit Score: 42.31 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 109 EVDSDGDGERRVNKGRNTDRVRADTSSDEEDDLKGNKKEPmevdddygrrgrrrsPKVMEKQGRERSHRGSRviADKPSD 188
Cdd:pfam10477 122 EGSPLNLQERRIGSGRLLPRDYKNQPADEARIEREKDRSP---------------NGSGSSRQDEEDQRNNQ--QNLRTF 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 189 EEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERR--GKEKNDRGSEGLLKRDRRERDLTDGHE----NGSRRRESE 262
Cdd:pfam10477 185 SGRHNERGRDGDRRSKRNRRTFGRFQYDGKKPVDRGRRisNKDKFSFQDRGKRYNSRRRNDSYTEEEpewfSAGPTSQHE 264
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15220892 263 RKDRSRRDDGVRDEKERRHNDKYDDSQRDKLRKEDSRKREEKKIEVP-KPKLAELNPSENNA 323
Cdd:pfam10477 265 TIELHGFDDKEEDNKRRSRTRVKTESFKELDLECNGGVSEEPESSSIlSLNVVEEQESPKKE 326
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
72-315 |
3.63e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 72 DKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRIEVDSDgdgERRVNKGRNTDRVRADTSSDEEDDLKgNKKEPMEV 151
Cdd:pfam17380 299 ERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQE---RMAMERERELERIRQEERKRELERIR-QEEIAMEI 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 152 DDDYGRRGRRrspkvMEKQGRERSHRGSRVIADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKN 231
Cdd:pfam17380 375 SRMRELERLQ-----MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREME 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 232 DRGSEGLLKRDRRERDLTDGHEngsRRRESERKDRSRRDDGVRDEKERRHNDKYDDSQRDK-LRKEDSRKREEKKIEVPK 310
Cdd:pfam17380 450 RVRLEEQERQQQVERLRQQEEE---RKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAmIEEERKRKLLEKEMEERQ 526
|
....*
gi 15220892 311 PKLAE 315
Cdd:pfam17380 527 KAIYE 531
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
185-311 |
3.66e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 185 KPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGllKRDRRERDLTDGHENGSRRRESERK 264
Cdd:PRK10811 587 KPQEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRDNRTRREGRENREEN--RRNRRQAQQQTAETRESQQAEVTEK 664
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 15220892 265 DRSRRDDG--VRDEKERRHNDKYDDSQRDK--LRKEDSRKREEKKIEVPKP 311
Cdd:PRK10811 665 ARTQDEQQqaPRRERQRRRNDEKRQAQQEAkaLNVEEQSVQETEQEERVQQ 715
|
|
| U2AF_lg |
TIGR01642 |
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ... |
168-280 |
7.80e-03 |
|
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.
Pssm-ID: 273727 [Multi-domain] Cd Length: 509 Bit Score: 39.88 E-value: 7.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 168 EKQGRERSHRGSRviaDKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRgkekndrgsegllKRDRRERD 247
Cdd:TIGR01642 21 SERPRRRSRDRSR---FRDRHRRSRERSYREDSRPRDRRRYDSRSPRSLRYSSVRRSRD-------------RPRRRSRS 84
|
90 100 110
....*....|....*....|....*....|...
gi 15220892 248 LTDGHENGSRRRESERKDRSRRDDGVRDEKERR 280
Cdd:TIGR01642 85 VRSIEQHRRRLRDRSPSNQWRKDDKKRSLWDIK 117
|
|
| SF-CC1 |
TIGR01622 |
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ... |
29-140 |
8.18e-03 |
|
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.
Pssm-ID: 273721 [Multi-domain] Cd Length: 494 Bit Score: 39.90 E-value: 8.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 29 RRSRTETDDVARRVRVSDDEDRKSSRRDleiggtvadgEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRI 108
Cdd:TIGR01622 11 RDSSSAGDRDRRRDKGRERSRDRSRDRE----------RSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRRRRG 80
|
90 100 110
....*....|....*....|....*....|..
gi 15220892 109 EVDSDGDGERRvnKGRNTDRVRADTSSDEEDD 140
Cdd:TIGR01622 81 DSYRRRRDDRR--SRREKPRARDGTPEPLTED 110
|
|
| SF-CC1 |
TIGR01622 |
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ... |
103-273 |
9.38e-03 |
|
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.
Pssm-ID: 273721 [Multi-domain] Cd Length: 494 Bit Score: 39.52 E-value: 9.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 103 DRGKRIEVDSDGDGERRVNKGRNTDRVRadtssDEEDDLKGNKKEPMEVDDDYgrrgrrrsPKVMEKQGRERSHRGSRVI 182
Cdd:TIGR01622 6 ERERLRDSSSAGDRDRRRDKGRERSRDR-----SRDRERSRSRRRDRHRDRDY--------YRGRERRSRSRRPNRRYRP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220892 183 ADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNdrgseglLKRDRRERDLTDGHENGSRRRESE 262
Cdd:TIGR01622 73 REKRRRRGDSYRRRRDDRRSRREKPRARDGTPEPLTEDERDRRTVFVQQ-------LAARARERDLYEFFSKVGKVRDVQ 145
|
170
....*....|...
gi 15220892 263 R-KDR-SRRDDGV 273
Cdd:TIGR01622 146 IiKDRnSRRSKGV 158
|
|
| |
