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Conserved domains on  [gi|15218830|ref|NP_176759|]
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polyamine oxidase 4 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02268 PLN02268
probable polyamine oxidase
 29-464 0e+00

probable polyamine oxidase


:

Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 908.30  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   29 PSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVSDENPLAPIIRRLGLTLYRTS 108
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFPVDMGASWLHGVCNENPLAPLIGRLGLPLYRTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  109 GDDSILYDHDLESYGLFDMHGNKIPPQLVTKVGDAFKRILEETEKIRDETANDMSVLQGISIVLDRNPELRQEGMAYEVL 188
Cdd:PLN02268  81 GDNSVLYDHDLESYALFDMDGNQVPQELVTKVGETFERILEETEKVRDEHEEDMSLLQAISIVLERHPELRLEGLAHEVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  189 QWYLCRMEAWFAVDANLISLKCWDQDECLSGGHGLMVQGYEPVIRTIAKDLDIRLNHRVTKVVRTSnNKVIVAVEGGTNF 268
Cdd:PLN02268 161 QWYLCRMEGWFAADADTISLKSWDQEELLEGGHGLMVRGYDPVINTLAKGLDIRLNHRVTKIVRRY-NGVKVTVEDGTTF 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  269 VADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWPNVEFLGMVAPTSYACGYFLNLHKATG 348
Cdd:PLN02268 240 VADAAIIAVPLGVLKANIIKFEPELPEWKEEAISDLGVGIENKIALHFDSVFWPNVEFLGVVAPTSYGCSYFLNLHKATG 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  349 HPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFPDAPDPAQYLVTRWGTDPNTLGCYAYDVVGMPEDLYPRLGEPVD 428
Cdd:PLN02268 320 HPVLVYMPAGRLARDIEKLSDEAAANFAMSQLKKMLPDATEPVQYLVSRWGSDPNSLGCYSYDLVGKPHDLYERLRAPVD 399

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 15218830  429 NIFFGGEAVNVEHQGSAHGAFLAGVSASQNCQRYIF 464
Cdd:PLN02268 400 NLFFAGEATSSDFPGSVHGAYSTGVMAAEECRMRLL 435
 
Name Accession Description Interval E-value
PLN02268 PLN02268
probable polyamine oxidase
 29-464 0e+00

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 908.30  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   29 PSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVSDENPLAPIIRRLGLTLYRTS 108
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFPVDMGASWLHGVCNENPLAPLIGRLGLPLYRTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  109 GDDSILYDHDLESYGLFDMHGNKIPPQLVTKVGDAFKRILEETEKIRDETANDMSVLQGISIVLDRNPELRQEGMAYEVL 188
Cdd:PLN02268  81 GDNSVLYDHDLESYALFDMDGNQVPQELVTKVGETFERILEETEKVRDEHEEDMSLLQAISIVLERHPELRLEGLAHEVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  189 QWYLCRMEAWFAVDANLISLKCWDQDECLSGGHGLMVQGYEPVIRTIAKDLDIRLNHRVTKVVRTSnNKVIVAVEGGTNF 268
Cdd:PLN02268 161 QWYLCRMEGWFAADADTISLKSWDQEELLEGGHGLMVRGYDPVINTLAKGLDIRLNHRVTKIVRRY-NGVKVTVEDGTTF 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  269 VADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWPNVEFLGMVAPTSYACGYFLNLHKATG 348
Cdd:PLN02268 240 VADAAIIAVPLGVLKANIIKFEPELPEWKEEAISDLGVGIENKIALHFDSVFWPNVEFLGVVAPTSYGCSYFLNLHKATG 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  349 HPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFPDAPDPAQYLVTRWGTDPNTLGCYAYDVVGMPEDLYPRLGEPVD 428
Cdd:PLN02268 320 HPVLVYMPAGRLARDIEKLSDEAAANFAMSQLKKMLPDATEPVQYLVSRWGSDPNSLGCYSYDLVGKPHDLYERLRAPVD 399

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 15218830  429 NIFFGGEAVNVEHQGSAHGAFLAGVSASQNCQRYIF 464
Cdd:PLN02268 400 NLFFAGEATSSDFPGSVHGAYSTGVMAAEECRMRLL 435
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 38-457 2.08e-107

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 327.14  E-value: 2.08e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830    38 ISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGvsDENPLAPIIRRLGLTLYRTSGDDSILYDH 117
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHG--AQPPLLALLKELGLEDRLVLPDPAPFYTV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   118 DLESYGLFDMHGNKIPPQLVTKVGDAFKRILEE---------TEKIRDETANDMSVLQGISIVLDRNPELRQEGMAYEVL 188
Cdd:pfam01593  79 LFAGGRRYPGDFRRVPAGWEGLLEFGRLLSIPEklrlglaalASDALDEFDLDDFSLAESLLFLGRRGPGDVEVWDRLID 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   189 QWYLCRMEAWFAVDA----NLISLKCWDQDECLSGGHG--LMVQ-GYEPVIRTIAK---DLDIRLNHRVTKvVRTSNNKV 258
Cdd:pfam01593 159 PELFAALPFASGAFAgdpsELSAGLALPLLWALLGEGGslLLPRgGLGALPDALAAqllGGDVRLNTRVRS-IDREGDGV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   259 IVAVEGGTNFVADAVIITVPIGVLKAnlIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWPN------VEFLGMVAP 332
Cdd:pfam01593 238 TVTLTDGEVIEADAVIVTVPLGVLKR--ILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDlgllglLSELLTGLG 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   333 TSYACgYFLNLHKATGHPVL--VYMAAGNLAQDLEKLSDEATANFVMLQLKKMFP-DAPDPAQYLVTRWGTDPNTLGCYA 409
Cdd:pfam01593 316 TAFSW-LTFPNRAPPGKGLLllVYVGPGDRARELEGLSDEELLQAVLRDLRKLFGeEAPEPLRVLVSDWHTDPWPRGSYS 394

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 15218830   410 YDVVGMPEDLYPRLGEPVD-NIFFGGEAVNVEHQGSAHGAFLAGVSASQ 457
Cdd:pfam01593 395 LPQYGPGHDDYRPLARTPDpGLFFAGEHTSTGYPGTVEGAIESGRRAAR 443
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
28-469 4.10e-93

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 289.90  E-value: 4.10e-93
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYS--FGCPVDMGASWLHGVSDEnpLAPIIRRLGLTLY 105
Cdd:COG1231   7 GKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFgdDGLYAELGAMRIPPSHTN--LLALARELGLPLE 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 106 RTSGDDSILYdhdlesyglFDMHGNKIPpqlVTKVGDAFKRILEETEKIRDETANDMSVLQGISIVLDRNP---ELRQEG 182
Cdd:COG1231  85 PFPNENGNAL---------LYLGGKRVR---AGEIAADLRGVAELLAKLLRALAAALDPWAHPAAELDRESlaeWLRRNG 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 183 MAYEVLQWYLCRMEAWFAVDANLISLKCWDQDECLSGGHGLM---VQGYEPVIRTIAKDL--DIRLNHRVTKVVRTSnNK 257
Cdd:COG1231 153 ASPSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGGGAQQfriVGGMDQLPRALAAELgdRIRLGAPVTRIRQDG-DG 231

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 258 VIVAVEGGTNFVADAVIITVPIGVLKAnlIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWpnvEFLGMVAPTSYAC 337
Cdd:COG1231 232 VTVTTDDGGTVRADAVIVTVPPSVLRR--IEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFW---EEDGLYGGISLTD 306

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 338 G-----YFLNLHKATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMF-PDAPDPAQYLVTRWGTDPNTLGCYAYD 411
Cdd:COG1231 307 LpirqtWYPSNGPDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFgVYAAEPVDYVSTDWGRDPWSRGAYAAA 386

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 15218830 412 VVGMPEDLYPRLGEPVDNIFFGGEAVNVEHQGSAHGAFLAGVSASQNcqryIFERLGA 469
Cdd:COG1231 387 PPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAE----ILARLGG 440
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 31-84 3.88e-07

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 52.28  E-value: 3.88e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15218830    31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGR---IHTDysfGCPVDMGASWL 84
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRagvLEDD---GFRFDTGPTVI 54
 
Name Accession Description Interval E-value
PLN02268 PLN02268
probable polyamine oxidase
 29-464 0e+00

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 908.30  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   29 PSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVSDENPLAPIIRRLGLTLYRTS 108
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFPVDMGASWLHGVCNENPLAPLIGRLGLPLYRTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  109 GDDSILYDHDLESYGLFDMHGNKIPPQLVTKVGDAFKRILEETEKIRDETANDMSVLQGISIVLDRNPELRQEGMAYEVL 188
Cdd:PLN02268  81 GDNSVLYDHDLESYALFDMDGNQVPQELVTKVGETFERILEETEKVRDEHEEDMSLLQAISIVLERHPELRLEGLAHEVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  189 QWYLCRMEAWFAVDANLISLKCWDQDECLSGGHGLMVQGYEPVIRTIAKDLDIRLNHRVTKVVRTSnNKVIVAVEGGTNF 268
Cdd:PLN02268 161 QWYLCRMEGWFAADADTISLKSWDQEELLEGGHGLMVRGYDPVINTLAKGLDIRLNHRVTKIVRRY-NGVKVTVEDGTTF 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  269 VADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWPNVEFLGMVAPTSYACGYFLNLHKATG 348
Cdd:PLN02268 240 VADAAIIAVPLGVLKANIIKFEPELPEWKEEAISDLGVGIENKIALHFDSVFWPNVEFLGVVAPTSYGCSYFLNLHKATG 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  349 HPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFPDAPDPAQYLVTRWGTDPNTLGCYAYDVVGMPEDLYPRLGEPVD 428
Cdd:PLN02268 320 HPVLVYMPAGRLARDIEKLSDEAAANFAMSQLKKMLPDATEPVQYLVSRWGSDPNSLGCYSYDLVGKPHDLYERLRAPVD 399

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 15218830  429 NIFFGGEAVNVEHQGSAHGAFLAGVSASQNCQRYIF 464
Cdd:PLN02268 400 NLFFAGEATSSDFPGSVHGAYSTGVMAAEECRMRLL 435
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 38-457 2.08e-107

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 327.14  E-value: 2.08e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830    38 ISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGvsDENPLAPIIRRLGLTLYRTSGDDSILYDH 117
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHG--AQPPLLALLKELGLEDRLVLPDPAPFYTV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   118 DLESYGLFDMHGNKIPPQLVTKVGDAFKRILEE---------TEKIRDETANDMSVLQGISIVLDRNPELRQEGMAYEVL 188
Cdd:pfam01593  79 LFAGGRRYPGDFRRVPAGWEGLLEFGRLLSIPEklrlglaalASDALDEFDLDDFSLAESLLFLGRRGPGDVEVWDRLID 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   189 QWYLCRMEAWFAVDA----NLISLKCWDQDECLSGGHG--LMVQ-GYEPVIRTIAK---DLDIRLNHRVTKvVRTSNNKV 258
Cdd:pfam01593 159 PELFAALPFASGAFAgdpsELSAGLALPLLWALLGEGGslLLPRgGLGALPDALAAqllGGDVRLNTRVRS-IDREGDGV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   259 IVAVEGGTNFVADAVIITVPIGVLKAnlIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWPN------VEFLGMVAP 332
Cdd:pfam01593 238 TVTLTDGEVIEADAVIVTVPLGVLKR--ILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDlgllglLSELLTGLG 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   333 TSYACgYFLNLHKATGHPVL--VYMAAGNLAQDLEKLSDEATANFVMLQLKKMFP-DAPDPAQYLVTRWGTDPNTLGCYA 409
Cdd:pfam01593 316 TAFSW-LTFPNRAPPGKGLLllVYVGPGDRARELEGLSDEELLQAVLRDLRKLFGeEAPEPLRVLVSDWHTDPWPRGSYS 394

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 15218830   410 YDVVGMPEDLYPRLGEPVD-NIFFGGEAVNVEHQGSAHGAFLAGVSASQ 457
Cdd:pfam01593 395 LPQYGPGHDDYRPLARTPDpGLFFAGEHTSTGYPGTVEGAIESGRRAAR 443
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
28-469 4.10e-93

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 289.90  E-value: 4.10e-93
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYS--FGCPVDMGASWLHGVSDEnpLAPIIRRLGLTLY 105
Cdd:COG1231   7 GKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFgdDGLYAELGAMRIPPSHTN--LLALARELGLPLE 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 106 RTSGDDSILYdhdlesyglFDMHGNKIPpqlVTKVGDAFKRILEETEKIRDETANDMSVLQGISIVLDRNP---ELRQEG 182
Cdd:COG1231  85 PFPNENGNAL---------LYLGGKRVR---AGEIAADLRGVAELLAKLLRALAAALDPWAHPAAELDRESlaeWLRRNG 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 183 MAYEVLQWYLCRMEAWFAVDANLISLKCWDQDECLSGGHGLM---VQGYEPVIRTIAKDL--DIRLNHRVTKVVRTSnNK 257
Cdd:COG1231 153 ASPSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGGGAQQfriVGGMDQLPRALAAELgdRIRLGAPVTRIRQDG-DG 231

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 258 VIVAVEGGTNFVADAVIITVPIGVLKAnlIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWpnvEFLGMVAPTSYAC 337
Cdd:COG1231 232 VTVTTDDGGTVRADAVIVTVPPSVLRR--IEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFW---EEDGLYGGISLTD 306

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 338 G-----YFLNLHKATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMF-PDAPDPAQYLVTRWGTDPNTLGCYAYD 411
Cdd:COG1231 307 LpirqtWYPSNGPDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFgVYAAEPVDYVSTDWGRDPWSRGAYAAA 386

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 15218830 412 VVGMPEDLYPRLGEPVDNIFFGGEAVNVEHQGSAHGAFLAGVSASQNcqryIFERLGA 469
Cdd:COG1231 387 PPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAE----ILARLGG 440
PLN02976 PLN02976
amine oxidase
 31-453 5.54e-80

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 272.13  E-value: 5.54e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830    31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDY-SFGCPVDMGASWLHGVSDE-------NPLAPIIRRLGL 102
Cdd:PLN02976  696 IIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTDRsSLSVPVDLGASIITGVEADvaterrpDPSSLICAQLGL 775

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   103 TLYRTSGDdSILYDhdlesyglfDMHGNKIPPQLVTKVGDAFKRILEETEKI---RDETANDMSVLQGISIVLDRN---- 175
Cdd:PLN02976  776 ELTVLNSD-CPLYD---------VVTGEKVPADLDEALEAEYNSLLDDMVLLvaqKGEHAMKMSLEDGLEYALKRRrmpr 845

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   176 --PELRQEGMA------YE--------------------------VLQWYLCRMEAWFAVDANLISLKCWDQDEC---LS 218
Cdd:PLN02976  846 pgVDIDETELGnaaddlYDsastgvdgghcekeskedvlsplerrVMNWHFAHLEYGCAALLKEVSLPYWNQDDVyggFG 925

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   219 GGHGLMVQGYEPVIRTIAKDLDIRLNHRVTKVV---------RTSNNKVIVAVEGGTNFVADAVIITVPIGVLKANLIQF 289
Cdd:PLN02976  926 GAHCMIKGGYSNVVESLAEGLDIHLNHVVTDVSygskdagasGSSRKKVKVSTSNGSEFLGDAVLITVPLGCLKAETIKF 1005

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   290 EPELPQWKTSAISGLGVGNENKIALRFDRAFW-PNVEFLGMVAPTSY---ACGYFLNLHKATGHPVLVYMAAGNLAQDLE 365
Cdd:PLN02976 1006 SPPLPDWKYSSIQRLGFGVLNKVVLEFPEVFWdDSVDYFGATAEETDlrgQCFMFWNVKKTVGAPVLIALVVGKAAIDGQ 1085

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   366 KLSDEATANFVMLQLKKMFPDA--PDPAQYLVTRWGTDPNTLGCYAYDVVGMPEDLYPRLGEPVDN-IFFGGEAVNVEHQ 442
Cdd:PLN02976 1086 SMSSSDHVNHALMVLRKLFGEAlvPDPVASVVTDWGRDPFSYGAYSYVAIGASGEDYDILGRPVENcLFFAGEATCKEHP 1165

                         490
                  ....*....|.
gi 15218830   443 GSAHGAFLAGV 453
Cdd:PLN02976 1166 DTVGGAMMSGL 1176
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 28-461 3.77e-67

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 230.65  E-value: 3.77e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPV----DMGASWLHGVSDeNPLAPIIRRLGLT 103
Cdd:PLN02328 238 PANVVVVGAGLAGLVAARQLLSMGFKVVVLEGRARPGGRVKTMKMKGDGVvaaaDLGGSVLTGING-NPLGVLARQLGLP 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  104 LYRTSgDDSILYDHDlesyglfdmhGNKIPPQLVTKVGDAFKRILEETEKIRD---ETANDMSVLQGISIVLDRN----P 176
Cdd:PLN02328 317 LHKVR-DICPLYLPD----------GKAVDAEIDSKIEASFNKLLDRVCKLRQamiEEVKSVDVNLGTALEAFRHvykvA 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  177 ELRQEGMayeVLQWYLCRMEAWFAVDANLISLKCWDQDEC--LSGGHGLMVQGYEPVIRTIAKDLDIrLNHRVTKVVRTS 254
Cdd:PLN02328 386 EDPQERM---LLNWHLANLEYANASLMSNLSMAYWDQDDPyeMGGDHCFIPGGNDTFVRELAKDLPI-FYERTVESIRYG 461

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  255 NNKVIVAVeGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFW-PNVEFLGMVAPT 333
Cdd:PLN02328 462 VDGVIVYA-GGQEFHGDMVLCTVPLGVLKKGSIEFYPELPQRKKDAIQRLGYGLLNKVALLFPYNFWgGEIDTFGHLTED 540

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  334 SYACGYFLNLH---KATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMF-PDA---PDPAQYLVTRWGTDPNTLG 406
Cdd:PLN02328 541 PSMRGEFFLFYsysSVSGGPLLIALVAGDAAVKFETLSPVESVKRVLQILRGIFhPKGivvPDPVQAVCTRWGKDCFTYG 620

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15218830  407 CYAYDVVGMPEDLYPRLGEPVDN--IFFGGEAVNVEHQGSAHGAFLAGVSASQNCQR 461
Cdd:PLN02328 621 SYSYVAVGSSGDDYDILAESVGDgrVFFAGEATNKQYPATMHGAFLSGMREAANILR 677
PLN03000 PLN03000
amine oxidase
 30-466 1.54e-66

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 229.91  E-value: 1.54e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   30 SVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDY----SFGCPVDMGASWLHGVSDeNPLAPIIRRLGLTLY 105
Cdd:PLN03000 186 SVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTKKmeanRVGAAADLGGSVLTGTLG-NPLGIIARQLGSSLY 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  106 RTSgDDSILYDHDlesyglfdmhGNKIPPQLVTKVGDAFKRILEETEKIRdETANDMSVLQGISIVLDRNPELRQEGMAY 185
Cdd:PLN03000 265 KVR-DKCPLYRVD----------GKPVDPDVDLKVEVAFNQLLDKASKLR-QLMGDVSMDVSLGAALETFRQVSGNDVAT 332

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  186 E---VLQWYLCRMEAWFAVDANLISLKCWDQDEC--LSGGHGLMVQGYEPVIRTIAKDLDIrLNHRVTKVVRTSNNKVIV 260
Cdd:PLN03000 333 EemgLFNWHLANLEYANAGLVSKLSLAFWDQDDPydMGGDHCFLPGGNGRLVQALAENVPI-LYEKTVQTIRYGSNGVKV 411

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  261 aVEGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFW-PNVEFLG-MVAPTSYACG 338
Cdd:PLN03000 412 -IAGNQVYEGDMVLCTVPLGVLKNGSIKFVPELPQRKLDCIKRLGFGLLNKVAMLFPYVFWsTDLDTFGhLTEDPNYRGE 490

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  339 YFLNLHKAT--GHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFP----DAPDPAQYLVTRWGTDPNTLGCYAYDV 412
Cdd:PLN03000 491 FFLFYSYAPvaGGPLLIALVAGEAAHKFETMPPTDAVTRVLHILRGIYEpqgiNVPDPLQTVCTRWGGDPFSLGSYSNVA 570

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15218830  413 VGMPEDLYPRLGEPVDN--IFFGGEAVNVEHQGSAHGAFLAGVSASQNCQRYIFER 466
Cdd:PLN03000 571 VGASGDDYDILAESVGDgrLFFAGEATTRRYPATMHGAFVTGLREAANMAQSAKAR 626
PLN02676 PLN02676
polyamine oxidase
 29-456 4.77e-63

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 213.04  E-value: 4.77e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   29 PSVIVIGSGISGLAAARNLSEASFK-VTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGV--SDENPLAPIIRRLGLTLY 105
Cdd:PLN02676  27 PSVIIVGAGMSGISAAKTLSEAGIEdILILEATDRIGGRMRKANFAGVSVELGANWVEGVggPESNPIWELANKLKLRTF 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  106 RTsgddsilyDHDLESYGLFDMHGNKIPPQLVTK---VGDAFKRILEE-TEKIRDETANDMSVL--QGISIVLDRNP-EL 178
Cdd:PLN02676 107 YS--------DFDNLSSNIYKQDGGLYPKKVVQKsmkVADASDEFGENlSISLSAKKAVDISILtaQRLFGQVPKTPlEM 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  179 rqegmayeVLQWYLCRMEawFAVDANLISLKC---------WDQDECLSGGHglmvQGYEPVIRTIAKD---------LD 240
Cdd:PLN02676 179 --------VIDYYNYDYE--FAEPPRVTSLKNtepnptfvdFGEDEYFVADP----RGYESLVYYLAEQflstksgkiTD 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  241 IRLnhRVTKVVRT---SNNKVIVAVEGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFD 317
Cdd:PLN02676 245 PRL--KLNKVVREisySKNGVTVKTEDGSVYRAKYVIVSVSLGVLQSDLIKFKPPLPDWKIEAIYQFDMAVYTKIFLKFP 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  318 RAFWPN---VEFLgmvaptSYAC---GYF-LNLHKATGHP---VLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMF-PD 386
Cdd:PLN02676 323 YKFWPSgpgTEFF------LYAHerrGYYpFWQHLENEYPgsnVLFVTVTDEESRRIEQQPDSETKAEIMEVLRKMFgPN 396

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  387 APDPAQYLVTRWGTDPNTLGCYAYDVVGMPEDLYPRLGEPVDNIFFGGEAVNVEHQGSAHGAFLAGVSAS 456
Cdd:PLN02676 397 IPEATDILVPRWWSNRFFKGSYSNWPIGVSRYEFDQIRAPVGRVYFTGEHTSEKYNGYVHGAYLAGIDTA 466
PLN02529 PLN02529
lysine-specific histone demethylase 1
 30-457 2.18e-57

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 202.81  E-value: 2.18e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   30 SVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFG----CPVDMGASWLHGVSdENPLAPIIRRLGLTLY 105
Cdd:PLN02529 162 SVIIVGAGLAGLAAARQLLSFGFKVVVLEGRNRPGGRVYTQKMGRkgqfAAVDLGGSVITGIH-ANPLGVLARQLSIPLH 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  106 RTSgDDSILYDHDlesyglfdmhGNKIPPQLVTKVGDAFKRILE---ETEKIRDETANDMSvlqgISIVLDRNPELRQEG 182
Cdd:PLN02529 241 KVR-DNCPLYKPD----------GALVDKEIDSNIEFIFNKLLDkvtELRQIMGGFANDIS----LGSVLERLRQLYGVA 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  183 MAYE---VLQWYLCRMEAWFAVDANLISLKCWDQDEC--LSGGHGLMVQGYEPVIRTIAKDLDIRLNHRVtKVVRTSNNK 257
Cdd:PLN02529 306 RSTEerqLLDWHLANLEYANAGCLSDLSAAYWDQDDPyeMGGDHCFLAGGNWRLINALCEGVPIFYGKTV-DTIKYGNDG 384

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  258 VIVaVEGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFW-PNVEFLGMVAPTSYA 336
Cdd:PLN02529 385 VEV-IAGSQVFQADMVLCTVPLGVLKKRTIRFEPELPRRKLAAIDRLGFGLLNKVAMVFPSVFWgEELDTFGCLNESSNK 463

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  337 CGYFL---NLHKATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFP----DAPDPAQYLVTRWGTDPNTLGCYA 409
Cdd:PLN02529 464 RGEFFlfyGYHTVSGGPALVALVAGEAAQRFENTDPSTLLHRVLSVLRGIYNpkgiNVPDPIQTICTRWGSDPLSYGSYS 543

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 15218830  410 YDVVGMPEDLYPRLGEPVDN-IFFGGEAVNVEHQGSAHGAFLAGV-SASQ 457
Cdd:PLN02529 544 HVRVQSSGSDYDILAESVSGrLFFAGEATTRQYPATMHGAFLSGLrEASR 593
PLN02568 PLN02568
polyamine oxidase
 28-462 1.16e-43

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 161.92  E-value: 1.16e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   28 QPSVIVIGSGISGLAAARNLSEAS-----FKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVsDENPLAPIIRRLGl 102
Cdd:PLN02568   5 KPRIVIIGAGMAGLTAANKLYTSSaandmFELTVVEGGDRIGGRINTSEFGGERIEMGATWIHGI-GGSPVYKIAQEAG- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  103 tlyRTSGDDSI-LYDHDLESYGLFDMHGNKIPPQLVTKVGDAFKRILEETE---------------KIRDETANDMSVLQ 166
Cdd:PLN02568  83 ---SLESDEPWeCMDGFPDRPKTVAEGGFEVDPSIVESISTLFRGLMDDAQgkliepsevdevdfvKLAAKAARVCESGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  167 GISI--------------VLDRNPELRQEGMAYEVLQwylcrmEAWFAVDAN----------LISLKCWDQDE--CLSGG 220
Cdd:PLN02568 160 GGSVgsflrrgldaywdsVSADEQIKGYGGWSRKLLE------EAIFTMHENtqrtytsaddLSTLDLAAESEyrMFPGE 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  221 HGLMVQGYEPVIRTIAKDLD---IRLNHRVTKVVRTSnNKVIVAVEGGTNFVADAVIITVPIGVLKANLIQ----FEPEL 293
Cdd:PLN02568 234 EITIAKGYLSVIEALASVLPpgtIQLGRKVTRIEWQD-EPVKLHFADGSTMTADHVIVTVSLGVLKAGIGEdsglFSPPL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  294 PQWKTSAISGLGVGNENKIALRF---------DRAFWPnveFLGMVAPTSYACGYFLNL-------------HKATGhpV 351
Cdd:PLN02568 313 PDFKTDAISRLGFGVVNKLFVELsprpdgspeDVAKFP---FLQMAFHRSDSEARHDKIpwwmrrtasicpiHKNSS--V 387

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  352 LVYMAAGNLAQDLEKLSDEATANFVMLQLKKmFPDAPDPA------------------------QYLVTRWGTDPNTLGC 407
Cdd:PLN02568 388 LLSWFAGKEALELEKLSDEEIIRGVQTTLSS-FLKRRVAGlgsqshplcnggassndgsrwkfvKVLKSKWGTDPLFLGS 466

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15218830  408 YAYDVVGMPEDLYPRLGEPVDN-------------IFFGGEAVNVEHQGSAHGAFLAGV-SASQNCQRY 462
Cdd:PLN02568 467 YSYVAVGSSGDDLDRMAEPLPRisdhdqaggpplqLLFAGEATHRTHYSTTHGAYFSGLrEANRLLQHY 535
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 28-398 3.11e-26

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 110.69  E-value: 3.11e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGAswlHGVSDENP-LAPIIRRLGLT--- 103
Cdd:COG1232   1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGFRIDRGP---HSFLTRDPeVLELLRELGLGdel 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 104 LYRTSGDDSILYDHDLESY--GLFDM-HGNKIPPQLVTKVG-DAFKRILEETEkirDETANDMsvlqgisiVLDRnpelr 179
Cdd:COG1232  78 VWPNTRKSYIYYGGKLHPLpqGPLALlRSPLLSLAGKLRALlELLAPRRPPGE---DESLAEF--------VRRR----- 141

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 180 qegMAYEVLQW----YLcrmEAWFAVDANLISLK-CWDQ-----DECLSGGHGLMVQ---------------GYEPVIRT 234
Cdd:COG1232 142 ---FGREVYERlvepLL---EGVYAGDPDELSADwAFPRlkrleLEHGSLIKGALALrkgakagevfgylrgGLGTLVEA 215

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 235 IAKDL---DIRLNHRVTKVVRTsNNKVIVAVEGGTNFVADAVIITVPIGVLkANLIQFEPELPQWKTSAISGLGVGNenk 311
Cdd:COG1232 216 LAEALeagEIRLGTRVTAIERE-GGGWRVTTSDGETIEADAVVSATPAPAL-ARLLAPLPPEVAAALAGIPYASVAV--- 290

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 312 IALRFDRAFWPNVEFLGMVAPTS-----YACGYFLNL--HKATGHPVLVYMAAGNL-AQDLEKLSDEATANFVMLQLKKM 383
Cdd:COG1232 291 VALGFDRPDLPPPDGFGWLVPRDegvpiLAVTFSSNKwpHRAPDGKVLLRLEVGGAgDPELWQLSDEELVALALADLRKL 370

                       410
                ....*....|....*
gi 15218830 384 FPDAPDPAQYLVTRW 398
Cdd:COG1232 371 LGIDAEPVDTRVVRW 385
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 28-397 2.12e-19

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 90.30  E-value: 2.12e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIH--TDYSFGCPVDMGaswLHGVSDENP-LAPIIRRLG--- 101
Cdd:COG3349   3 PPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGGRARsfPDPDTGLPIDNG---QHVLLGCYRnTLDLLRRIGaad 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 102 -------LTLYRTSGDDSILYDHDL-----ESYGLFDMHGnkippqlvTKVGDAFK--RILEETEKIRDETANDMSVLQg 167
Cdd:COG3349  80 nlvgpepLQFPLPGGRRWTLRAPRLpaplhLLRALLRAPG--------LSLADRLAllRLLTACRERRWRELDDISVAD- 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 168 isiVLDRNpelRQEGMAYEVLqWY-LCRmeAWFAVDANLISLKC-WD--QDECLSGGHG------------LMVqgyEPV 231
Cdd:COG3349 151 ---WLRRH---GQSPRLIRRL-WEpLLL--AALNTPPEQASARLaLTvlRETLLAGPAAsdllvprgplseLFV---DPA 218

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 232 IRTI-AKDLDIRLNHRVTKVVRTSNNKVIVAVEGGTNFVADAVIITVPIGVLkANLIqfePELPQW---------KTSAI 301
Cdd:COG3349 219 LAYLeARGGEVRLGTRVRALEFDGGRVTGLVLADGETVPADAVVLAVPPEVA-ARLL---PELARLpelgllaplEYSPI 294

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 302 SGlgvgnenkIALRFDRAF-WPNVEFLGMVAPTSyacgYFLNLHKATGHPVLVYMAAgNL--AQDLEKLSDEATANFVML 378
Cdd:COG3349 295 VN--------VHLWLDRPVtLGPPPFAGLVGSTS----QWVFDRGAGDGGQGGVLSV-VIsaADRLLDLSREELAAEVWA 361

                       410       420
                ....*....|....*....|.
gi 15218830 379 QLKKMFPDAPD--PAQYLVTR 397
Cdd:COG3349 362 ELAALLPAAREalPVWSRVVR 382
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 31-287 2.07e-18

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 87.60  E-value: 2.07e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHT----DYSFgcpvDMGASWLhgvSDENPLAPIIRRLGLTLY- 105
Cdd:COG1233   6 VVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTferpGFRF----DVGPSVL---TMPGVLERLFRELGLEDYl 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 106 -----------RTSGDDSILYDHDLESYGlfdmhgnkippQLVTKV----GDAFKRILEETEKIRDETANDM--SVLQGI 168
Cdd:COG1233  79 elvpldpayrvPFPDGRALDLPRDLERTA-----------AELERLfpgdAEAYRRFLAELRRLYDALLEDLlyRPLLSL 147

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 169 SIVLDRN--PELRQEGM--AYEVLQWYLC--RMEAWFAVDANLISLkcwDQDECLSGGHGLMVQGYEP-----------V 231
Cdd:COG1233 148 RDLLRPLalARLLRLLLrsLRDLLRRYFKdpRLRALLAGQALYLGL---SPDRTPALYALIAYLEYAGgvwypkggmgaL 224

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15218830 232 IRTIAKDL-----DIRLNHRVTKVVrTSNNKVI-VAVEGGTNFVADAVIITVPIGVLKANLI 287
Cdd:COG1233 225 ADALARLAeelggEIRTGAEVERIL-VEGGRATgVRLADGEEIRADAVVSNADPAHTYLRLL 285
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
33-100 5.36e-16

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 72.18  E-value: 5.36e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15218830    33 VIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGvSDENPLAPIIRRL 100
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGYVFDYGAHIFHG-SDEPNVRDLLDEL 67
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 29-398 4.43e-15

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 77.20  E-value: 4.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   29 PSVIVIGSGISGLAAARNL--SEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGA-SWLhgVSDENPLApIIRRLGLTly 105
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLhkKGPDADITLLEASDRLGGKIQTVRKDGFPIELGPeSFL--ARKPSAPA-LVKELGLE-- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  106 rtsgdDSILYDHDLESYGLfdmHGNK-----------IPPQ--------LVTKVGDAfkRILEETEKIRDETANDMSV-- 164
Cdd:PRK11883  76 -----DELVANTTGQSYIY---VNGKlhpippgtvmgIPTSiapflfagLVSPIGKL--RAAADLRPPRWKPGQDQSVga 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  165 ------------------LQGI-----------SIVldrnPELRQ---------EGMAYEvlqwylcRMEAWFAVDANLI 206
Cdd:PRK11883 146 ffrrrfgdevvenlieplLSGIyagdidtlslrATF----PQLAQaedkygsllRGMRKA-------LPKEKKKTKGVFG 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  207 SLKcwdqdeclsgghglmvQGYEPVIRTIAKDLD---IRLNHRVTKVVRTSNNKVIVAVEGGTnFVADAVIITVPIGVLk 283
Cdd:PRK11883 215 TLK----------------GGLQSLIEALEEKLPagtIHKGTPVTKIDKSGDGYEIVLSNGGE-IEADAVIVAVPHPVL- 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  284 ANLIQFEPELPQWKTSAISGLGVgnenkIALRFDRAFWPNVEFLGMV-----APTSYACGYflnLHKATGHP-----VLV 353
Cdd:PRK11883 277 PSLFVAPPAFALFKTIPSTSVAT-----VALAFPESATNLPDGTGFLvarnsDYTITACTW---TSKKWPHTtpegkVLL 348

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 15218830  354 YMAAGNLAQD-LEKLSDEATANFVMLQLKKMFPDAPDPAQYLVTRW 398
Cdd:PRK11883 349 RLYVGRPGDEaVVDATDEELVAFVLADLSKVMGITGDPEFTIVQRW 394
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
28-457 4.92e-14

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 72.99  E-value: 4.92e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHgVSDEnplapiirrlgltlyrt 107
Cdd:COG3380   3 MPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGGRFDHGAQYFT-ARDP----------------- 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 108 sgddsilydhdlesyglfdmhgnkippqlvtkvgdAFKRILEetekirdetandmsvlqgisivldrnpELRQEGMAyev 187
Cdd:COG3380  65 -----------------------------------RFQALVE---------------------------EWLAAGLV--- 79

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 188 lqwylcrmEAWFavdANLISLKCWDQDECLSGGHGLMVqgYEPVIRTIAK----DLDIRLNHRVTKVVRTSNNKVIVAVE 263
Cdd:COG3380  80 --------APWT---FDFVVLDADGLVSPRDDGEPRYV--GVPGMNALAKhlaaGLDVRLGTRVTALERDGDGWRLTDED 146

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 264 GGTNFVADAVIITVPigvlkanliqfepeLPQwkTSAI--SGLGVGNENKIA-----------LRFDRAFWPNV------ 324
Cdd:COG3380 147 GEEYGPFDAVVLAIP--------------APQ--AAALlePSLAPELAAALAsvryrpcwavmLGFDQPLDPDWdaafvd 210

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 325 -EFLGMVAptsyacgyfLNLHK--ATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFPDA-PDPAQYLVTRWGt 400
Cdd:COG3380 211 dGPLAWIA---------RDSSKpgRPGEEAWVLHASPEWSREHLDDDPEEVAAALLAAFAELLGLPlAEPDWAQAHRWR- 280

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15218830 401 dpntlgcYAydvvgMPEDLYPR--LGEPVDNIFFGGEAVnveHQGSAHGAFLAGVSASQ 457
Cdd:COG3380 281 -------YA-----LPEAPLGApfLWDADLGLGLCGDWC---AGGRVEGAWLSGLALAR 324
PRK07233 PRK07233
hypothetical protein; Provisional
 33-386 2.41e-13

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 71.84  E-value: 2.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   33 VIGSGISGLAAARNLSEASFKVTVLESRDRIGG----------RIHTDYSFGCPVD---------MGAS----WLHGV-- 87
Cdd:PRK07233   4 IVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGlaasfefgglPIERFYHHIFKSDeallelldeLGLEdklrWRETKtg 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830   88 --------SDENPLApIIR----------RLGL-TLYRTSGDDSILYDHDLESYGLFDMHGNKI-----PPQLVTKVGDA 143
Cdd:PRK07233  84 yyvdgklyPLGTPLE-LLRfphlslidkfRLGLlTLLARRIKDWRALDKVPAEEWLRRWSGEGVyevfwEPLLESKFGDY 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  144 FKRIleetekirdetandmS---VLQGISIVLDRNPELRQEGMAYevlqwylcrmeawfavdanlislkcwdqdecLSGG 220
Cdd:PRK07233 163 ADDV---------------SaawLWSRIKRRGNRRYSLFGEKLGY-------------------------------LEGG 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  221 HGLMVQGYEPVIRtiAKDLDIRLNHRVTKVVRtsNNKVIVAVEGGTNFVA-DAVIITVPIGVLkANLIQFEPELPQWKTS 299
Cdd:PRK07233 197 FATLIDALAEAIE--ARGGEIRLGTPVTSVVI--DGGGVTGVEVDGEEEDfDAVISTAPPPIL-ARLVPDLPADVLARLR 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  300 AISGLGVGNenkIALRFDRA----FWPNV-----EFLGMVAPTSyacgyFLNLHKATG-HpvLVYMAAgNLAQDLEK--L 367
Cdd:PRK07233 272 RIDYQGVVC---MVLKLRRPltdyYWLNIndpgaPFGGVIEHTN-----LVPPERYGGeH--LVYLPK-YLPGDHPLwqM 340

                        410
                 ....*....|....*....
gi 15218830  368 SDEATANFVMLQLKKMFPD 386
Cdd:PRK07233 341 SDEELLDRFLSYLRKMFPD 359
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
21-69 3.40e-08

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 55.51  E-value: 3.40e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 15218830  21 MQKQNnvqpsVIVIGSGISGLAAARNLSEAsFKVTVLESRDRIGGRIHT 69
Cdd:COG2907   1 MARMR-----IAVIGSGISGLTAAWLLSRR-HDVTLFEANDRLGGHTHT 43
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
31-276 4.79e-08

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 54.91  E-value: 4.79e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  31 VIVIGSGISGLAAARNLSEASFKVTVLEsRDRIGgrihtdysfgcpvdMGASW--------LHGVSDENPLAPIIRRlGL 102
Cdd:COG0665   5 VVVIGGGIAGLSTAYHLARRGLDVTVLE-RGRPG--------------SGASGrnagqlrpGLAALADRALVRLARE-AL 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 103 TLYRT-SGDDSIlyDHDLESYGLFDMHGNKippqlvtkvgdafkrilEETEKIRDETAndmsvlqgisivldrnpELRQE 181
Cdd:COG0665  69 DLWRElAAELGI--DCDFRRTGVLYLARTE-----------------AELAALRAEAE-----------------ALRAL 112

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830 182 GMAYEVL---QwyLCRMEAWFAVDANLISLkcWDQDeclsGGH---GLMVQGYepVIRTIAKDLDIRLNHRVTKVVRTSN 255
Cdd:COG0665 113 GLPVELLdaaE--LREREPGLGSPDYAGGL--YDPD----DGHvdpAKLVRAL--ARAARAAGVRIREGTPVTGLEREGG 182

                       250       260
                ....*....|....*....|.
gi 15218830 256 NKVIVAVEGGTnFVADAVIIT 276
Cdd:COG0665 183 RVTGVRTERGT-VRADAVVLA 202
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
20-78 8.07e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 54.87  E-value: 8.07e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15218830  20 LMQKQNNVQPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGR---IHTDYSFGCPVD 78
Cdd:COG1148 132 LEPIKVPVNKRALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRaaqLHKTFPGLDCPQ 193
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 28-65 9.97e-08

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 54.10  E-value: 9.97e-08
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:COG2072   6 HVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGG 43
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 31-65 3.24e-07

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 52.40  E-value: 3.24e-07
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 15218830    31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGS 36
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 31-84 3.88e-07

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 52.28  E-value: 3.88e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15218830    31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGR---IHTDysfGCPVDMGASWL 84
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRagvLEDD---GFRFDTGPTVI 54
PLN02576 PLN02576
protoporphyrinogen oxidase
 30-69 4.64e-07

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 52.32  E-value: 4.64e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 15218830   30 SVIVIGSGISGLAAARNL-SEASFKVTVLESRDRIGGRIHT 69
Cdd:PLN02576  14 DVAVVGAGVSGLAAAYALaSKHGVNVLVTEARDRVGGNITS 54
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 31-92 8.78e-07

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 51.38  E-value: 8.78e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15218830    31 VIVIGSGISGLAAARNLS----EASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVSDENP 92
Cdd:TIGR00562   5 VVIIGGGISGLCAAYYLEkeipELPVELTLVEASDRVGGKIQTVKEDGYLIERGPDSFLERKKSAP 70
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 30-65 1.52e-06

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 50.56  E-value: 1.52e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 15218830   30 SVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:PRK11749 142 KVAVIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG 177
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 30-65 1.30e-05

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 47.47  E-value: 1.30e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 15218830   30 SVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:PRK12810 145 KVAVVGSGPAGLAAADQLARAGHKVTVFERADRIGG 180
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 30-65 1.81e-05

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 47.05  E-value: 1.81e-05
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 15218830  30 SVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:COG0493 123 KVAVVGSGPAGLAAAYQLARAGHEVTVFEALDKPGG 158
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 31-74 2.52e-05

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 46.51  E-value: 2.52e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15218830    31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGriHTDYSFG 74
Cdd:pfam00890   2 VLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGG--ATAWSSG 43
PRK13984 PRK13984
putative oxidoreductase; Provisional
 10-65 6.81e-05

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 45.53  E-value: 6.81e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15218830   10 DNLPEGTISELM-QKQNNVQPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:PRK13984 264 DNVPVEKYSEILdDEPEKKNKKVAIVGSGPAGLSAAYFLATMGYEVTVYESLSKPGG 320
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 27-74 8.97e-05

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 44.89  E-value: 8.97e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 15218830   27 VQPSVIVIGSGISGLAAARNLSEASFKVTVL--ESRDRIGGRIHtdYSFG 74
Cdd:PRK12834   3 MDADVIVVGAGLAGLVAAAELADAGKRVLLLdqENEANLGGQAF--WSLG 50
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
25-64 1.49e-04

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 43.87  E-value: 1.49e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 15218830   25 NNVQPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIG 64
Cdd:PRK08163   1 MTKVTPVLIVGGGIGGLAAALALARQGIKVKLLEQAAEIG 40
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 28-66 1.94e-04

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 43.39  E-value: 1.94e-04
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 15218830  28 QPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGR 66
Cdd:COG0654   3 RTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPD 41
PRK07208 PRK07208
hypothetical protein; Provisional
 29-65 2.09e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 43.72  E-value: 2.09e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 15218830   29 PSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:PRK07208   5 KSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGG 41
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 31-69 2.25e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 43.67  E-value: 2.25e-04
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 15218830  31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGriHT 69
Cdd:COG1053   6 VVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGG--HT 42
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
31-64 3.64e-04

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 42.83  E-value: 3.64e-04
                        10        20        30
                ....*....|....*....|....*....|....*
gi 15218830  31 VIVIGSGISGLAAARNLSEA-SFKVTVLESRDRIG 64
Cdd:COG0579   7 VVIIGAGIVGLALARELSRYeDLKVLVLEKEDDVA 41
PLN02612 PLN02612
phytoene desaturase
 240-457 6.58e-04

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 42.14  E-value: 6.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  240 DIRLNHRVTKVVRTSNNKVI-VAVEGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKT-SAISGLGVGN-----ENKI 312
Cdd:PLN02612 324 EVRLNSRIKKIELNDDGTVKhFLLTNGSVVEGDVYVSATPVDILKLLLPDQWKEIPYFKKlDKLVGVPVINvhiwfDRKL 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218830  313 ALRFDRAFWPNVEFLGMVAPTSYACGYFLNLHKATGHpvLVYMAAgnlaQDLEKLSDEATANFVMLQLKKMFPD--APDP 390
Cdd:PLN02612 404 KNTYDHLLFSRSPLLSVYADMSTTCKEYYDPNKSMLE--LVFAPA----EEWISRSDEDIIDATMKELAKLFPDeiSADQ 477

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15218830  391 AQYLVTRwgtdpntlgcyaYDVVGMPEDLY----------PRLGEPVDNIFFGGEAVNVEHQGSAHGAFLAGVSASQ 457
Cdd:PLN02612 478 SKAKILK------------YHVVKTPRSVYktvpncepcrPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQ 542
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 31-65 9.77e-04

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 41.63  E-value: 9.77e-04
                        10        20        30
                ....*....|....*....|....*....|....*
gi 15218830  31 VIVIGSGISGLAAARNLSEAsFKVTVLeSRDRIGG 65
Cdd:COG0029   7 VLVIGSGIAGLSAALKLAER-GRVTLL-TKGELGE 39
PLN02612 PLN02612
phytoene desaturase
 31-67 1.26e-03

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 41.37  E-value: 1.26e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 15218830   31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRI 67
Cdd:PLN02612  96 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKV 132
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
31-69 1.38e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 40.87  E-value: 1.38e-03
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 15218830  31 VIVIGSGISGLAAARNLSEASFKVTVLEsRDRIGGRIHT 69
Cdd:COG0492   3 VVIIGAGPAGLTAAIYAARAGLKTLVIE-GGEPGGQLAT 40
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 29-60 2.27e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.99  E-value: 2.27e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 15218830    29 PSVIVIGSGISGLAAARNLSEASFKVTVLESR 60
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDE 32
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 31-65 2.39e-03

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 40.46  E-value: 2.39e-03
                        10        20        30
                ....*....|....*....|....*....|....*
gi 15218830  31 VIVIGSGISGLAAARNLSEASFKVTVLEsRDRIGG 65
Cdd:COG1249   6 LVVIGAGPGGYVAAIRAAQLGLKVALVE-KGRLGG 39
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 31-64 3.49e-03

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 39.83  E-value: 3.49e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 15218830   31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIG 64
Cdd:PRK01747 263 AAIIGGGIAGAALALALARRGWQVTLYEADEAPA 296
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
31-65 4.27e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 39.37  E-value: 4.27e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 15218830   31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGG 65
Cdd:PRK05249   8 LVVIGSGPAGEGAAMQAAKLGKRVAVIERYRNVGG 42
PRK07804 PRK07804
L-aspartate oxidase; Provisional
 31-57 5.32e-03

L-aspartate oxidase; Provisional


Pssm-ID: 236102 [Multi-domain]  Cd Length: 541  Bit Score: 39.18  E-value: 5.32e-03
                         10        20
                 ....*....|....*....|....*..
gi 15218830   31 VIVIGSGISGLAAARNLSEASFKVTVL 57
Cdd:PRK07804  19 VVVVGSGVAGLTAALAARRAGRRVLVV 45
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
37-70 6.61e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 38.41  E-value: 6.61e-03
                        10        20        30
                ....*....|....*....|....*....|....
gi 15218830  37 GISGLAAARNLSEASFKVTVLESRDRIGGRIHTD 70
Cdd:COG0644   2 GPAGSAAARRLARAGLSVLLLEKGSFPGDKICGG 35
Thi4 pfam01946
Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.
 31-65 9.00e-03

Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.


Pssm-ID: 460393  Cd Length: 232  Bit Score: 37.84  E-value: 9.00e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 15218830    31 VIVIGSGISGLAAARNLSEAS-FKVTVLESRDRIGG 65
Cdd:pfam01946  20 VVIVGAGSSGLTAAYYLAKNRgLKVAIIERSVSPGG 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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