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Conserved domains on  [gi|1519012578|gb|AYY41734|]
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right-handed parallel beta-helix repeat-containing protein [Pseudomonas aeruginosa]

Protein Classification

right-handed parallel beta-helix repeat-containing protein( domain architecture ID 17609036)

right-handed parallel beta-helix repeat-containing protein that may share some similarity with pectate lyases, similar to Pseudomonas putida mannuronan C5-epimerase that catalyzes the epimerization of beta-D-mannuronate to alpha-L-guluronate during the synthesis of the linear polysaccharide alginate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
epimerase_AlgG super family cl45661
mannuronan 5-epimerase AlgG;
23-543 0e+00

mannuronan 5-epimerase AlgG;


The actual alignment was detected with superfamily member NF038177:

Pssm-ID: 468398 [Multi-domain]  Cd Length: 519  Bit Score: 1041.35  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  23 VLGAVLLHGQAWAAQpvekpqpVPAQAGNEPGLTQGLKETGNYTVTTAPAEPLHLDPPKLPDLSGYTAAAVEAKIVRKPG 102
Cdd:NF038177    6 LLGALLLASGAAQAA-------VPAQPEAPRQLAKELQQAKTYTVTSAPIEPLEMDPPKLPDLSGYTAAAVEKKIVRKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 103 GRASVQRMVQQQPLKEFTGGSNRLAEWVKRQRQMPQAIFIEGGYVNLAQLAGKLPASALEQVEPGVFVARLPIVVSQGAT 182
Cdd:NF038177   79 GKISVARMMQETALKEFTGGDNKLAEWVVRQHGIPQAIFIEDGYVNLGQLAKKVPKQYLSEVEPGVYVARLPIVVGQGGI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 183 LDIDKQVKELRLSQERGAFLVNDGMLFVRDSKVTGWSESKKEPAWFKTPNEFRPFLISWGGAEVYLSNSTFTSFGYNASK 262
Cdd:NF038177  159 LEIDKKVKELRLSQERGAFLVNDGKLFVTDTKVTGWSEKNNGPAAYRTPKEFRPFLLSWGGTETYISNTKMASFGYNTSK 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 263 AYGISISQYSPGMDKQMKRPRPKGWVIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVYGIDPHDRSHRLIIADNTVHGT 342
Cdd:NF038177  239 SYGVSISQYTPNMAKRLKRPEPTGWIIDSEFSDMWYGFYCYETDDFVVKGNTYRDNIVYGIDPHDRSHRLIIAENTVYGT 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 343 RKKHGIIVSREVNDSFIFNNRSYENKLSGIVLDRNSEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRVR 422
Cdd:NF038177  319 KKKHGIIVSREVNDSFIFNNRSYDNKLSGIVLDRNSVGNLVAYNEVYRNHTDGITLYESGDNLLWGNRVIANRRHGIRVR 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 423 NSVNIRLYENLAAGNQLIGVYGHIKDLTNTDRNIALDPFDTKVSLIVVGGKLAGNGSGPLSVDSPLSLELYRVAMLAPTK 502
Cdd:NF038177  399 NSVNIRLYENLAMANGLTGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSGNGSGPLSIDSPLSVELYRVSMLAPTK 478

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 1519012578 503 SSGISLPGVLGEKQDQILDLLVRQDKAVLIDPVESQAELQD 543
Cdd:NF038177  479 SSGISLNGVLGERQDEILDLLVRQQKAVLIDPVESQTELQD 519
 
Name Accession Description Interval E-value
epimerase_AlgG NF038177
mannuronan 5-epimerase AlgG;
23-543 0e+00

mannuronan 5-epimerase AlgG;


Pssm-ID: 468398 [Multi-domain]  Cd Length: 519  Bit Score: 1041.35  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  23 VLGAVLLHGQAWAAQpvekpqpVPAQAGNEPGLTQGLKETGNYTVTTAPAEPLHLDPPKLPDLSGYTAAAVEAKIVRKPG 102
Cdd:NF038177    6 LLGALLLASGAAQAA-------VPAQPEAPRQLAKELQQAKTYTVTSAPIEPLEMDPPKLPDLSGYTAAAVEKKIVRKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 103 GRASVQRMVQQQPLKEFTGGSNRLAEWVKRQRQMPQAIFIEGGYVNLAQLAGKLPASALEQVEPGVFVARLPIVVSQGAT 182
Cdd:NF038177   79 GKISVARMMQETALKEFTGGDNKLAEWVVRQHGIPQAIFIEDGYVNLGQLAKKVPKQYLSEVEPGVYVARLPIVVGQGGI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 183 LDIDKQVKELRLSQERGAFLVNDGMLFVRDSKVTGWSESKKEPAWFKTPNEFRPFLISWGGAEVYLSNSTFTSFGYNASK 262
Cdd:NF038177  159 LEIDKKVKELRLSQERGAFLVNDGKLFVTDTKVTGWSEKNNGPAAYRTPKEFRPFLLSWGGTETYISNTKMASFGYNTSK 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 263 AYGISISQYSPGMDKQMKRPRPKGWVIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVYGIDPHDRSHRLIIADNTVHGT 342
Cdd:NF038177  239 SYGVSISQYTPNMAKRLKRPEPTGWIIDSEFSDMWYGFYCYETDDFVVKGNTYRDNIVYGIDPHDRSHRLIIAENTVYGT 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 343 RKKHGIIVSREVNDSFIFNNRSYENKLSGIVLDRNSEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRVR 422
Cdd:NF038177  319 KKKHGIIVSREVNDSFIFNNRSYDNKLSGIVLDRNSVGNLVAYNEVYRNHTDGITLYESGDNLLWGNRVIANRRHGIRVR 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 423 NSVNIRLYENLAAGNQLIGVYGHIKDLTNTDRNIALDPFDTKVSLIVVGGKLAGNGSGPLSVDSPLSLELYRVAMLAPTK 502
Cdd:NF038177  399 NSVNIRLYENLAMANGLTGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSGNGSGPLSIDSPLSVELYRVSMLAPTK 478

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 1519012578 503 SSGISLPGVLGEKQDQILDLLVRQDKAVLIDPVESQAELQD 543
Cdd:NF038177  479 SSGISLNGVLGERQDEILDLLVRQQKAVLIDPVESQTELQD 519
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 288-443 1.06e-18

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 87.66  E-value: 1.06e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 288 VIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVYGIDPHD-----RSHRLIIADNTVHGTRkkHGIIVSReVNDSFIFNN 362
Cdd:COG3420   111 IENNRIENNLFGIYLEGSDNNVIRNNTISGNRDLRADRGNgihlwNSPGNVIEGNTISGGR--DGIYLEF-SDNNVIRNN 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 363 R------------SYENKLSGIVLDRN--------SEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRhGIRVR 422
Cdd:COG3420   188 TirnlrygihymySNDNLVEGNTFRDNgagialmySKGNTVRGNTILGNSGYGILLKESSDSVIEGNTISGNGK-GIFIY 266

                         170       180
                  ....*....|....*....|.
gi 1519012578 423 NSVNIRLYENLAAGNQlIGVY 443
Cdd:COG3420   267 NSNRNTIRGNLFAGNG-IGIH 286
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 298-443 1.16e-15

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 74.37  E-value: 1.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 298 YGFYCYEADDLVVKGNTYRDNIVYGIDPHDrSHRLIIADNTVHGTRkKHGIIVSREVNdSFIFNNRSYENKLSGIVLdRN 377
Cdd:pfam13229   1 SGILLNGSSNATIKNNTISNNGGYGIYLRG-SSNATIENNTITNNG-GDGIEISGSSN-NTISNNTISNNGGGGIAL-RG 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1519012578 378 SEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRV-RNSVNIRLYENLAAGNQLIGVY 443
Cdd:pfam13229  77 SSNNLIENNTISNNGGAGIYLSDSSNNTIENNIIHNNGGSGIVIeDSSNNVTISNNTVTNNKGAGIL 143
CASH smart00722
Domain present in carbohydrate binding proteins and sugar hydrolses;
262-422 7.54e-09

Domain present in carbohydrate binding proteins and sugar hydrolses;


Pssm-ID: 214788  Cd Length: 153  Bit Score: 54.82  E-value: 7.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  262 KAYGISISQYSPGMDKQ--MKRPRPKGWVIDSTivDSWYGFYCYEADDLVVKGNTYRD--NIVYGIDPHDRSHrliiadn 337
Cdd:smart00722   1 IANGTVLELLRGAVHYMytSDIGGSGGAVIDMG--SGRGSNITINSNDVRVDGVTIGGdgNAVTGIYVSASGD------- 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  338 tvhgtrkkHGIIVSREVNDSFIFN---NRSYENKLSGIVLDRNSEGNlVAYNEVYRNHS---DGITLYESGDSLLWGNQV 411
Cdd:smart00722  72 --------PVIQNDGTGKNLIIDNvtfNGTEINSGAGIVVTAGSEGL-FIGNRIIGNYVatgDGNYLSDSSGGDLIGNRI 142

                          170
                   ....*....|.
gi 1519012578  412 LANRRHGIRVR 422
Cdd:smart00722 143 YDNNRDGIAVV 153
para_beta_helix TIGR03804
parallel beta-helix repeat (two copies); This model represents a tandem pair of an ...
 395-437 4.54e-03

parallel beta-helix repeat (two copies); This model represents a tandem pair of an approximately 22-amino acid (each) repeat homologous to the beta-strand repeats that stack in a right-handed parallel beta-helix in the periplasmic C-5 mannuronan epimerase, AlgA, of Pseudomonas aeruginosa. A homology domain consisting of a longer tandem array of these repeats is described in the SMART database as CASH (SM00722), and is found in many carbohydrate-binding proteins and sugar hydrolases. A single repeat is represented by SM00710. This TIGRFAMs model represents a flavor of the parallel beta-helix-forming repeat based on prokaryotic sequences only in its seed alignment, although it also finds many eukaryotic sequences.


Pssm-ID: 274795 [Multi-domain]  Cd Length: 44  Bit Score: 35.18  E-value: 4.54e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1519012578 395 GITLYESGDSLLWGNQVLANRrHGIRVRNSVNIRLYENLAAGN 437
Cdd:TIGR03804   1 GIYLESSSNNTLSNNTASNNS-YGIYLYDSSNNTLSNNTASNN 42
 
Name Accession Description Interval E-value
epimerase_AlgG NF038177
mannuronan 5-epimerase AlgG;
23-543 0e+00

mannuronan 5-epimerase AlgG;


Pssm-ID: 468398 [Multi-domain]  Cd Length: 519  Bit Score: 1041.35  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  23 VLGAVLLHGQAWAAQpvekpqpVPAQAGNEPGLTQGLKETGNYTVTTAPAEPLHLDPPKLPDLSGYTAAAVEAKIVRKPG 102
Cdd:NF038177    6 LLGALLLASGAAQAA-------VPAQPEAPRQLAKELQQAKTYTVTSAPIEPLEMDPPKLPDLSGYTAAAVEKKIVRKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 103 GRASVQRMVQQQPLKEFTGGSNRLAEWVKRQRQMPQAIFIEGGYVNLAQLAGKLPASALEQVEPGVFVARLPIVVSQGAT 182
Cdd:NF038177   79 GKISVARMMQETALKEFTGGDNKLAEWVVRQHGIPQAIFIEDGYVNLGQLAKKVPKQYLSEVEPGVYVARLPIVVGQGGI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 183 LDIDKQVKELRLSQERGAFLVNDGMLFVRDSKVTGWSESKKEPAWFKTPNEFRPFLISWGGAEVYLSNSTFTSFGYNASK 262
Cdd:NF038177  159 LEIDKKVKELRLSQERGAFLVNDGKLFVTDTKVTGWSEKNNGPAAYRTPKEFRPFLLSWGGTETYISNTKMASFGYNTSK 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 263 AYGISISQYSPGMDKQMKRPRPKGWVIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVYGIDPHDRSHRLIIADNTVHGT 342
Cdd:NF038177  239 SYGVSISQYTPNMAKRLKRPEPTGWIIDSEFSDMWYGFYCYETDDFVVKGNTYRDNIVYGIDPHDRSHRLIIAENTVYGT 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 343 RKKHGIIVSREVNDSFIFNNRSYENKLSGIVLDRNSEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRVR 422
Cdd:NF038177  319 KKKHGIIVSREVNDSFIFNNRSYDNKLSGIVLDRNSVGNLVAYNEVYRNHTDGITLYESGDNLLWGNRVIANRRHGIRVR 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 423 NSVNIRLYENLAAGNQLIGVYGHIKDLTNTDRNIALDPFDTKVSLIVVGGKLAGNGSGPLSVDSPLSLELYRVAMLAPTK 502
Cdd:NF038177  399 NSVNIRLYENLAMANGLTGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSGNGSGPLSIDSPLSVELYRVSMLAPTK 478

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 1519012578 503 SSGISLPGVLGEKQDQILDLLVRQDKAVLIDPVESQAELQD 543
Cdd:NF038177  479 SSGISLNGVLGERQDEILDLLVRQQKAVLIDPVESQTELQD 519
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 288-443 1.06e-18

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 87.66  E-value: 1.06e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 288 VIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVYGIDPHD-----RSHRLIIADNTVHGTRkkHGIIVSReVNDSFIFNN 362
Cdd:COG3420   111 IENNRIENNLFGIYLEGSDNNVIRNNTISGNRDLRADRGNgihlwNSPGNVIEGNTISGGR--DGIYLEF-SDNNVIRNN 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 363 R------------SYENKLSGIVLDRN--------SEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRhGIRVR 422
Cdd:COG3420   188 TirnlrygihymySNDNLVEGNTFRDNgagialmySKGNTVRGNTILGNSGYGILLKESSDSVIEGNTISGNGK-GIFIY 266

                         170       180
                  ....*....|....*....|.
gi 1519012578 423 NSVNIRLYENLAAGNQlIGVY 443
Cdd:COG3420   267 NSNRNTIRGNLFAGNG-IGIH 286
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 298-443 1.16e-15

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 74.37  E-value: 1.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 298 YGFYCYEADDLVVKGNTYRDNIVYGIDPHDrSHRLIIADNTVHGTRkKHGIIVSREVNdSFIFNNRSYENKLSGIVLdRN 377
Cdd:pfam13229   1 SGILLNGSSNATIKNNTISNNGGYGIYLRG-SSNATIENNTITNNG-GDGIEISGSSN-NTISNNTISNNGGGGIAL-RG 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1519012578 378 SEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRV-RNSVNIRLYENLAAGNQLIGVY 443
Cdd:pfam13229  77 SSNNLIENNTISNNGGAGIYLSDSSNNTIENNIIHNNGGSGIVIeDSSNNVTISNNTVTNNKGAGIL 143
NosD pfam05048
Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to ...
 288-438 1.21e-12

Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.


Pssm-ID: 428281 [Multi-domain]  Cd Length: 215  Bit Score: 67.06  E-value: 1.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 288 VIDSTIVDSWYGFYCYEADDLVVKGNTYRDNiVYGIdpH-DRSHRLIIADNTVHGTRKkhGIIVSrEVNDSFIFNNRSYE 366
Cdd:pfam05048  32 ISNNDIINSRDGIYLDASNNNTITGNRISNL-RYGI--HlMNSNDNTISDNVFSGNTA--GIALM-SSSNNTLENNTISG 105

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1519012578 367 NKLSGIVLDrNSEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANrRHGIRVRN-SVNIRLYENLAAGNQ 438
Cdd:pfam05048 106 NTNYGILLS-DSSNNTISNNTISNNNGKGIFLYNSDYNTITGNRITSN-GIGIHFLAgSNGNTIYNNYFINNS 176
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 288-427 3.95e-12

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 67.63  E-value: 3.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 288 VIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVyGIDPHDrSHRLIIADNTVHGTRKkHGIIVsREVNDSFIFNNRSYEN 367
Cdd:COG3420   184 IRNNTIRNLRYGIHYMYSNDNLVEGNTFRDNGA-GIALMY-SKGNTVRGNTILGNSG-YGILL-KESSDSVIEGNTISGN 259

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1519012578 368 KlSGIVLDrNSEGNLVAYNEVYRNHSdGITLY-ESGDSLLWGNQVLANRRHGIRVRNSVNI 427
Cdd:COG3420   260 G-KGIFIY-NSNRNTIRGNLFAGNGI-GIHLTaGSEGNRIYGNNFIGNRTQVKYVGGRDNE 317
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 241-405 4.84e-12

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 63.97  E-value: 4.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 241 WGGAEVYLSNSTFTSfgynaSKAYGISISQYSpgmdkqmkrprpkGWVIDSTIVDSW--YGFYCYEADDLVVKGNTYRDN 318
Cdd:pfam13229   6 NGSSNATIKNNTISN-----NGGYGIYLRGSS-------------NATIENNTITNNggDGIEISGSSNNTISNNTISNN 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 319 IVYGIDPHDrSHRLIIADNTVHGTrKKHGIIVSREvNDSFIFNNRSYENKLSGIVLDRNSEGNLVAYNEVYRNHSDGITL 398
Cdd:pfam13229  68 GGGGIALRG-SSNNLIENNTISNN-GGAGIYLSDS-SNNTIENNIIHNNGGSGIVIEDSSNNVTISNNTVTNNKGAGILI 144


                  ....*..
gi 1519012578 399 YESGDSL 405
Cdd:pfam13229 145 VGGSSNN 151
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 327-455 1.59e-11

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 62.42  E-value: 1.59e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 327 DRSHRLIIADNTVHGTrKKHGIIVsREVNDSFIFNNRSYENKLSGIVLdRNSEGNLVAYNEVYRNHSDGITLYESGDSLL 406
Cdd:pfam13229   6 NGSSNATIKNNTISNN-GGYGIYL-RGSSNATIENNTITNNGGDGIEI-SGSSNNTISNNTISNNGGGGIALRGSSNNLI 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1519012578 407 WGNQVLANRRHGIRVRNSVNIRLYENLAAGNQLIGVYGHIKDLTNTDRN 455
Cdd:pfam13229  83 ENNTISNNGGAGIYLSDSSNNTIENNIIHNNGGSGIVIEDSSNNVTISN 131
NosD pfam05048
Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to ...
 299-443 5.01e-11

Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.


Pssm-ID: 428281 [Multi-domain]  Cd Length: 215  Bit Score: 62.44  E-value: 5.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 299 GFYCYEADDLVVKGNT---YRDNIVygidpHDRSHRLIIADNTVHGTRkkHGIIVSrEVNDSFIFNNRSYENKlSGIVLD 375
Cdd:pfam05048  21 GIQLWNTEGNVISNNDiinSRDGIY-----LDASNNNTITGNRISNLR--YGIHLM-NSNDNTISDNVFSGNT-AGIALM 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1519012578 376 rNSEGNLVAYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRVRNSVNIRLYENLAAGNQlIGVY 443
Cdd:pfam05048  92 -SSSNNTLENNTISGNTNYGILLSDSSNNTISNNTISNNNGKGIFLYNSDYNTITGNRITSNG-IGIH 157
NosD COG3420
Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion ...
 304-443 2.21e-10

Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains [Inorganic ion transport and metabolism];


Pssm-ID: 442646 [Multi-domain]  Cd Length: 343  Bit Score: 62.24  E-value: 2.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 304 EADDLVVKGNTYR------DNIVYGIDPhDRSHRLIIADNTVHGTrkKHGIIVsREVNDSFIFNNRSYENKLS------G 371
Cdd:COG3420    76 TADNVTVRGLTITgsgdslTDDDAGIYV-RGADNAVIENNRIENN--LFGIYL-EGSDNNVIRNNTISGNRDLradrgnG 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1519012578 372 IVLDrNSEGNLVAYNEVyRNHSDGITLYESGDSLLWGNQVlANRRHGIRVRNSVNIRLYENLAAGNQlIGVY 443
Cdd:COG3420   152 IHLW-NSPGNVIEGNTI-SGGRDGIYLEFSDNNVIRNNTI-RNLRYGIHYMYSNDNLVEGNTFRDNG-AGIA 219
CASH smart00722
Domain present in carbohydrate binding proteins and sugar hydrolses;
262-422 7.54e-09

Domain present in carbohydrate binding proteins and sugar hydrolses;


Pssm-ID: 214788  Cd Length: 153  Bit Score: 54.82  E-value: 7.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  262 KAYGISISQYSPGMDKQ--MKRPRPKGWVIDSTivDSWYGFYCYEADDLVVKGNTYRD--NIVYGIDPHDRSHrliiadn 337
Cdd:smart00722   1 IANGTVLELLRGAVHYMytSDIGGSGGAVIDMG--SGRGSNITINSNDVRVDGVTIGGdgNAVTGIYVSASGD------- 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578  338 tvhgtrkkHGIIVSREVNDSFIFN---NRSYENKLSGIVLDRNSEGNlVAYNEVYRNHS---DGITLYESGDSLLWGNQV 411
Cdd:smart00722  72 --------PVIQNDGTGKNLIIDNvtfNGTEINSGAGIVVTAGSEGL-FIGNRIIGNYVatgDGNYLSDSSGGDLIGNRI 142

                          170
                   ....*....|.
gi 1519012578  412 LANRRHGIRVR 422
Cdd:smart00722 143 YDNNRDGIAVV 153
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 242-388 1.42e-08

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 53.95  E-value: 1.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 242 GGAEVYLSNSTFTSFGYNaskayGISISQYSpgmdkqmkrprpKGWVIDSTIVDSWY-GFYCYEADDLVVKGNTYRDNIV 320
Cdd:pfam13229  30 GSSNATIENNTITNNGGD-----GIEISGSS------------NNTISNNTISNNGGgGIALRGSSNNLIENNTISNNGG 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1519012578 321 YGIDPHDRSHrLIIADNTVHGTrKKHGIIVSREVNDSFIFNNRSYENKLSGIVLDRNSEGNLVAYNEV 388
Cdd:pfam13229  93 AGIYLSDSSN-NTIENNIIHNN-GGSGIVIEDSSNNVTISNNTVTNNKGAGILIVGGSSNNTVENNTF 158
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 199-362 2.75e-08

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 53.18  E-value: 2.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 199 GAFLVNDGMLFVRDSKVTGWSESkkepawfktpnefrPFLISwGGAEVYLSNSTFTSFGYnaskaYGISISQYSPGMdkq 278
Cdd:pfam13229  25 GIYLRGSSNATIENNTITNNGGD--------------GIEIS-GSSNNTISNNTISNNGG-----GGIALRGSSNNL--- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 279 mkrprpkgwVIDSTIVDSW-YGFYCYEADDLVVKGNTYRDNIVYGIDPHDRSHRLIIADNTVHGTrKKHGIIVSREVNDS 357
Cdd:pfam13229  82 ---------IENNTISNNGgAGIYLSDSSNNTIENNIIHNNGGSGIVIEDSSNNVTISNNTVTNN-KGAGILIVGGSSNN 151


                  ....*
gi 1519012578 358 FIFNN 362
Cdd:pfam13229 152 TVENN 156
Beta_helix pfam13229
Right handed beta helix region; This region contains a parallel beta helix region that shares ...
 370-456 3.63e-08

Right handed beta helix region; This region contains a parallel beta helix region that shares some similarity with Pectate lyases.


Pssm-ID: 463811 [Multi-domain]  Cd Length: 158  Bit Score: 52.79  E-value: 3.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 370 SGIVLDRNSEGNLVaYNEVYRNHSDGITLYESGDSLLWGNQVLANRRHGIRVRNSVNIRLYENLAAGNQLIGVYghikdL 449
Cdd:pfam13229   1 SGILLNGSSNATIK-NNTISNNGGYGIYLRGSSNATIENNTITNNGGDGIEISGSSNNTISNNTISNNGGGGIA-----L 74


                  ....*..
gi 1519012578 450 TNTDRNI 456
Cdd:pfam13229  75 RGSSNNL 81
NosD pfam05048
Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to ...
 239-386 1.39e-05

Periplasmic copper-binding protein (NosD); NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain.


Pssm-ID: 428281 [Multi-domain]  Cd Length: 215  Bit Score: 46.26  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 239 ISWGGAEVYLSNSTFTSFGYNASK--AYGISISqYSPGmdkqmkrprpkGWVIDSTIVDSWYGFYCYEADDLVVKGNTYR 316
Cdd:pfam05048  37 IINSRDGIYLDASNNNTITGNRISnlRYGIHLM-NSND-----------NTISDNVFSGNTAGIALMSSSNNTLENNTIS 104

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519012578 317 DNIVYGIDpHDRSHRLIIADNTVHGTRKKhGIIVSREVNDSfIFNNRSYENKlSGIVLDRNSEGNLVAYN 386
Cdd:pfam05048 105 GNTNYGIL-LSDSSNNTISNNTISNNNGK-GIFLYNSDYNT-ITGNRITSNG-IGIHFLAGSNGNTIYNN 170
para_beta_helix TIGR03804
parallel beta-helix repeat (two copies); This model represents a tandem pair of an ...
 395-437 4.54e-03

parallel beta-helix repeat (two copies); This model represents a tandem pair of an approximately 22-amino acid (each) repeat homologous to the beta-strand repeats that stack in a right-handed parallel beta-helix in the periplasmic C-5 mannuronan epimerase, AlgA, of Pseudomonas aeruginosa. A homology domain consisting of a longer tandem array of these repeats is described in the SMART database as CASH (SM00722), and is found in many carbohydrate-binding proteins and sugar hydrolases. A single repeat is represented by SM00710. This TIGRFAMs model represents a flavor of the parallel beta-helix-forming repeat based on prokaryotic sequences only in its seed alignment, although it also finds many eukaryotic sequences.


Pssm-ID: 274795 [Multi-domain]  Cd Length: 44  Bit Score: 35.18  E-value: 4.54e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1519012578 395 GITLYESGDSLLWGNQVLANRrHGIRVRNSVNIRLYENLAAGN 437
Cdd:TIGR03804   1 GIYLESSSNNTLSNNTASNNS-YGIYLYDSSNNTLSNNTASNN 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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