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Conserved domains on  [gi|1514763350|dbj|BBH22402|]
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protein lplB [Paenibacillus baekrokdamisoli]

Protein Classification

ABC transporter permease( domain architecture ID 10008345)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 11-310 2.69e-165

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 461.87  E-value: 2.69e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  11 KNDLMKRIFKYKALYLMLLPAVVFLIIFSYIPMYGATIAFKDFWIKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEIN 90
Cdd:COG4209    16 KKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLIS 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  91 LLRLIFGFPAPIVLAILLNEVRHKLFKRSIQTIVYLPHFISWVTISGIIFSILSNE-GLVNTIIRAFGGENVNFLTSNSM 169
Cdd:COG4209    96 LLKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDtGLVNQLLRALGGEPINFLTEPKY 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 170 FRPLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNGGFDQVFN 249
Cdd:COG4209   176 FRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYL 255

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1514763350 250 LYNTMVYDSGDVIDTYVYRIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKKLSGQGIY 310
Cdd:COG4209   256 LYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEESLF 316
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 11-310 2.69e-165

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 461.87  E-value: 2.69e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  11 KNDLMKRIFKYKALYLMLLPAVVFLIIFSYIPMYGATIAFKDFWIKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEIN 90
Cdd:COG4209    16 KKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLIS 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  91 LLRLIFGFPAPIVLAILLNEVRHKLFKRSIQTIVYLPHFISWVTISGIIFSILSNE-GLVNTIIRAFGGENVNFLTSNSM 169
Cdd:COG4209    96 LLKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDtGLVNQLLRALGGEPINFLTEPKY 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 170 FRPLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNGGFDQVFN 249
Cdd:COG4209   176 FRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYL 255

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1514763350 250 LYNTMVYDSGDVIDTYVYRIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKKLSGQGIY 310
Cdd:COG4209   256 LYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEESLF 316
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
26-236 8.88e-12

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 64.46  E-value: 8.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  26 LMLLPAVVFLIIFSYIPMyGATIAFKDFWIKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEINLLRLIFGFPAPIVLA 105
Cdd:PRK10561    1 LLVAPQLIITVIFFIWPA-GEALWYSLQSVDPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 106 ILLNEVRHklFKRSIQTIVYLPHFISWVtISGIIFSILSNEGL-VNTIIRAFGGENVNFLTSNSMFRPLLILSGIWKEIG 184
Cdd:PRK10561   80 ALVDYVVR--GSRFYQTLMLLPYAVAPA-VAAVLWIFLFNPGRgLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQIS 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1514763350 185 WGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNF 236
Cdd:PRK10561  157 YNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNL 208
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 26-224 2.16e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 51.99  E-value: 2.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  26 LMLLPAVVFLIIFSYIPMygATIAFKDFWIKKGilgsPWVGFAHFEKLFETDKFWQVFRNTIEINLLRLIFGFPAPIVLA 105
Cdd:TIGR03262   5 LLLAGMILALLLFLLLPL--LALLTKSVYDSDG----DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 106 ILLNEVRHKlFKRSIQTIVYLPHFISWVTiSGIIFS-ILSNEGLVNTIiraFGGENVnfltsnsmFRPLLILSGiwkEIG 184
Cdd:TIGR03262  79 YALTRSRIP-GKGAFRLVALLPLLAPSLL-PAISLIyLFGNQGLLKGL---LGGFSI--------YGFWGIVIG---EVF 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1514763350 185 W----GTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSM 224
Cdd:TIGR03262 143 YtfphALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGA 186
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 83-242 6.93e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 48.81  E-value: 6.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  83 FRNTIEINLLRLIFGFPAPIVLAILLNEVRHKLfKRSIQTIVYLPHFISWVTISGIIFSILSNEGLVNTIIrafggenvn 162
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILP--------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 163 fltsnSMFRPLLILSGIWKeIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNG 242
Cdd:cd06261    71 -----GLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 97-242 4.40e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.14  E-value: 4.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  97 GFPAPIVLAILLNEVRHKLFKRSIQTIVYLPHFisWVTISGIIFSILSNEGlvntiirafggenvnfltsnSMFRPLLIL 176
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSF--VLAILLVVIAILSILG--------------------HGILPAIIL 58

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1514763350 177 SgIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNG 242
Cdd:pfam00528  59 A-LLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGG 123
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 11-310 2.69e-165

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 461.87  E-value: 2.69e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  11 KNDLMKRIFKYKALYLMLLPAVVFLIIFSYIPMYGATIAFKDFWIKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEIN 90
Cdd:COG4209    16 KKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLIS 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  91 LLRLIFGFPAPIVLAILLNEVRHKLFKRSIQTIVYLPHFISWVTISGIIFSILSNE-GLVNTIIRAFGGENVNFLTSNSM 169
Cdd:COG4209    96 LLKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDtGLVNQLLRALGGEPINFLTEPKY 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 170 FRPLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNGGFDQVFN 249
Cdd:COG4209   176 FRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVGFEQIYL 255

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1514763350 250 LYNTMVYDSGDVIDTYVYRIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKKLSGQGIY 310
Cdd:COG4209   256 LYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEESLF 316
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
25-303 3.26e-55

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 181.10  E-value: 3.26e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  25 YLMLLPAVVFLIIFSYIPM-YGATIAFKDFwiKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEINLLRLIFGFPAPIV 103
Cdd:COG1175    21 YLFLLPALLLLLVFVLYPLlYTLYLSFTDW--NLLGPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 104 LAILLNEVRHklFKRSIQTIVYLPHFISWVtISGIIFSIL--SNEGLVNTIIRAFGGENVNFLTSNSMFRPLLILSGIWK 181
Cdd:COG1175    99 LALLLNRKLR--GRGFFRTLFFLPWVISPV-VVALIWKWLfnPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWK 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 182 EIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNF-GSMMNggFDQVFNLYNTMVYDSGD 260
Cdd:COG1175   176 GTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTiGALQV--FDLVYVLTGGGPGNSTT 253

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1514763350 261 VIDTYVYRIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKK 303
Cdd:COG1175   254 TLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 15-308 2.03e-12

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 66.32  E-value: 2.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  15 MKRIFKYKA-LYLMLLPAVVFLIIFSYIPM-YGATIAFKDFWIKKGILGSPwvGFAHFEKLFETDKFWQVFRNTIEI--- 89
Cdd:COG1176     1 MSAALRRRLrPLLLLLPALLWLLLFFVLPLlLLLVYSFTTRDPYGGVVPGF--TLENYARLFTDPLYLKVLLRTLWIall 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  90 -NLLRLIFGFPapivLAILLNEVRHKlFKRSIQTIVYLPHFISWVTISGIIFSILSNEGLVNTIIRAFG--GENVNFLTS 166
Cdd:COG1176    79 tTLICLLLGYP----IAYFLARAPPR-WRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGliDEPLRLLYT 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 167 NsmfrPLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVP--IISILL--ILNFGS---- 238
Cdd:COG1176   154 E----FAVVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPgiIAGSLLvfIPALGAfvtp 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1514763350 239 -MMNGGfdqvfnlyntmvydSGDVIDTYVYRIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKKLSGQG 308
Cdd:COG1176   230 aLLGGG--------------KVLMIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRLLG 286
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
26-236 8.88e-12

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 64.46  E-value: 8.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  26 LMLLPAVVFLIIFSYIPMyGATIAFKDFWIKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEINLLRLIFGFPAPIVLA 105
Cdd:PRK10561    1 LLVAPQLIITVIFFIWPA-GEALWYSLQSVDPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 106 ILLNEVRHklFKRSIQTIVYLPHFISWVtISGIIFSILSNEGL-VNTIIRAFGGENVNFLTSNSMFRPLLILSGIWKEIG 184
Cdd:PRK10561   80 ALVDYVVR--GSRFYQTLMLLPYAVAPA-VAAVLWIFLFNPGRgLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQIS 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1514763350 185 WGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNF 236
Cdd:PRK10561  157 YNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNL 208
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-305 8.03e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 62.49  E-value: 8.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  15 MKRIFKYKALYLMLLPAVvFLIIFSYIPMygatiafkdFWIkkgILGSPWVGFAHFEKLFETDKFWQVFRNTIEINLLRL 94
Cdd:COG1178     1 MSTRPRRRPRLLLLLLAL-LLALLVLLPL---------LAL---LLRAFTDGLANFWALLSDPYLWRALGNTLLLALLVT 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  95 IFGFPAPIVLAILLneVRHKL-FKRSIQTIVYLPHFI-SWVTISGIIfSILSNEGLVNTIIRAFGGENVNFLTSnsmFRP 172
Cdd:COG1178    68 LLSLLLGVPLAWLL--ARTDFpGRRLLRWLLLLPLALpPYVVALAWI-ALFGPNGLLNTLLRALFGLEPPDIYG---LGG 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 173 LLILSGIWkeigWGTIIYL---AALSGINPDLYEAATVDGANRFKQITHITLPSMVPII--SILLIL-----NFG--SMM 240
Cdd:COG1178   142 IILVLVLF----NYPYVYLllrAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIaaGALLVFllclaDFGtpLVL 217

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1514763350 241 NGGFdqvfnlyntmvydsgDVIDTYVYRIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKKLS 305
Cdd:COG1178   218 GGGY---------------TTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRR 267
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 15-236 4.54e-08

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 53.18  E-value: 4.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  15 MKRIFKYKALYLMLLPAVVFLIIFSYI---PMYGA-TIAFKDfwiKKGILGSPWVG------FAHFEKLFETDKFWQVFR 84
Cdd:COG0395     1 MSATARRRRRRLGRILLYLLLILLALLflfPLYWMvVTSFKP---PAEIFSGPPSLlpseftLENYRAAFTDGPFGRYLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  85 NTIEI----NLLRLIFGFPAPIVLAILlnEVRhklFKRSIQTIVYLPHFISWVTISGIIFSILSNEGLVNTIirafggen 160
Cdd:COG0395    78 NSLIVavvsTVLSLLLSSLAAYALARF--RFR---GRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTY-------- 144

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1514763350 161 vnfltsnsmfrPLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNF 236
Cdd:COG0395   145 -----------WGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTF 209
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 32-233 4.75e-08

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 53.19  E-value: 4.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  32 VVFLIIFSYIPM-YGATIAFKDFWIkkgiLGSPWVGF--AHFEKLFETDKFWQVFRNTIEI----NLLRLIFGFPAPIVL 104
Cdd:COG1177    13 LALVLLFLYLPIlVLVLYSFNDSWF----LTFPPEGFtlRWYAELFSDPRLLDALLNSLLIallsTLLATVLGTPAALAL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 105 AillnevRHKL-FKRSIQTIVYLPHFISWVtISGI-IFSILSNEGLVNTIIrafggenvnfltsnsmfrpLLILSGIWKE 182
Cdd:COG1177    89 A------RYRFrGRRLLLALLLLPLVVPGI-VLGVaLLLLFSALGLSGGLW-------------------GLILAHVVFT 142

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1514763350 183 IGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVP-IISILLI 233
Cdd:COG1177   143 LPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPgILAGALL 194
malF PRK10999
maltose ABC transporter permease MalF;
64-236 8.24e-08

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 53.43  E-value: 8.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  64 WVGFAHFEKLFeTDK-----FWQVFRNTIEINLLRLIFGFPAPIVLAILL--NEVRHKLFKRSIQTIVY-LPHFISWvti 135
Cdd:PRK10999  264 TIGWKNFTRVF-TDEgiqkpFIAIFIWTVVFSLLTVVLTVAVGMVLACLVqwEALKGKAVYRVLLILPYaVPSFISI--- 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 136 sgIIFSILSNE--GLVNTIIRAFGGENVNFLTSNSMFRPLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRF 213
Cdd:PRK10999  340 --LIFKGLFNQsfGEINMMLSALFGIKPAWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPF 417

                         170       180
                  ....*....|....*....|...
gi 1514763350 214 KQITHITLPSMVPIISILLILNF 236
Cdd:PRK10999  418 QNFFKITLPLLIKPLTPLMIASF 440
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 26-224 2.16e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 51.99  E-value: 2.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  26 LMLLPAVVFLIIFSYIPMygATIAFKDFWIKKGilgsPWVGFAHFEKLFETDKFWQVFRNTIEINLLRLIFGFPAPIVLA 105
Cdd:TIGR03262   5 LLLAGMILALLLFLLLPL--LALLTKSVYDSDG----DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 106 ILLNEVRHKlFKRSIQTIVYLPHFISWVTiSGIIFS-ILSNEGLVNTIiraFGGENVnfltsnsmFRPLLILSGiwkEIG 184
Cdd:TIGR03262  79 YALTRSRIP-GKGAFRLVALLPLLAPSLL-PAISLIyLFGNQGLLKGL---LGGFSI--------YGFWGIVIG---EVF 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1514763350 185 W----GTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSM 224
Cdd:TIGR03262 143 YtfphALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGA 186
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 83-242 6.93e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 48.81  E-value: 6.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  83 FRNTIEINLLRLIFGFPAPIVLAILLNEVRHKLfKRSIQTIVYLPHFISWVTISGIIFSILSNEGLVNTIIrafggenvn 162
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILP--------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 163 fltsnSMFRPLLILSGIWKeIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNG 242
Cdd:cd06261    71 -----GLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 97-242 4.40e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.14  E-value: 4.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  97 GFPAPIVLAILLNEVRHKLFKRSIQTIVYLPHFisWVTISGIIFSILSNEGlvntiirafggenvnfltsnSMFRPLLIL 176
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSF--VLAILLVVIAILSILG--------------------HGILPAIIL 58

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1514763350 177 SgIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNG 242
Cdd:pfam00528  59 A-LLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGG 123
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
23-303 1.00e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 46.69  E-value: 1.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  23 ALYLMLLPAVVFLII-FSYIPMYGATIAFKDFWikkgilgspwvGFAHFEKLFETDKFWQVFRNTIEINLLRLIFGFPAP 101
Cdd:COG1178   290 ALALCLLLVLLGLLLpLLALLLWSLTKALDDNL-----------TLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLA 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 102 IVLAILLNEVRHKLfKRSIQTIVYLPHfiswvTISGIIFSIlsneGLVNTIIRAFGgenvnFLTSNSMFrpLLILSGIWK 181
Cdd:COG1178   359 LLLAYLVRRRRGRL-ARLLDRLAMLPY-----AVPGIVLGL----GLLLLFNRPLP-----LLLYGTLA--ILVLAYVVR 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 182 EIGWGTIIYLAALSGINPDLYEAATVDGANRFKQITHITLPSMVPIISILLILNFGSMMNGgfdqvFNLYNTMVYDSGDV 261
Cdd:COG1178   422 FLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKE-----LSATLLLRPPGFET 496

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1514763350 262 IDTYVYRIgLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKK 303
Cdd:COG1178   497 LAVLIYQL-ASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 16-261 1.01e-04

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 43.07  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  16 KRIFKYKALYLMLLPAVVFLIIFSYiPMYGAtiafkdfwIKKGILGSPWVGFAHFEKLFETDKFWQVFRNTIEI----NL 91
Cdd:PRK15050   17 RRRRRLRPLLWLLLPLLVLAPLVVY-PLVRV--------VLQSLTGEHGLGLATYRAVLGSPDFRGALLTTLQIafasTA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  92 LRLIFGFpapiVLAILLNEVRH---KLFKRSIQTIVYLPHFIswVTISgIIFsILSNEGLVN-TIIRAFGGENvnfltsn 167
Cdd:PRK15050   88 GCLVLGV----LLALVLAFVPFpgaSLVGRFIDTFVAFPSFL--ITLA-FTF-LYGSAGSVNiALQRLFGLEA------- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 168 smfRPLLILSGIWKEIGWGTIIY--------LAALSGINPDLYEAATVDGANRFKQITHITLPSMVP------IISILLI 233
Cdd:PRK15050  153 ---PPLDFLYSPGGVILAEITFYtpfvvrplLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPalaaggSLCLLLT 229

                         250       260
                  ....*....|....*....|....*....
gi 1514763350 234 LN-FGSMMNGGFDQVFNLyNTMVYDSGDV 261
Cdd:PRK15050  230 LNeFGIVLFTGAKDVVTL-PVLIYSKAIV 257
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 67-236 5.91e-04

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 40.90  E-value: 5.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350  67 FAHFEKLFETDKFWQVFRNTIEIN----LLRLIFGFPAPIVLAillnevRHK-LFKRSIQTIVYL----PHFISWVTIsg 137
Cdd:COG3833    59 LENYKKLFTETPFLRWFLNSLIVAvvtaIISVFLAALAAYAFS------RFRfKGRKAGLLALLLlqmfPAFLALVAL-- 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 138 iiFSILSNEGLVNTIIrafggenvnfltsnsmfrpLLILSGIWKEIGWGTIIYLAALSGINPDLYEAATVDGANRFKQIT 217
Cdd:COG3833   131 --YLLLSALGLLNTLL-------------------GLILVYLGGAIPFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFF 189

                         170
                  ....*....|....*....
gi 1514763350 218 HITLPSMVPIISILLILNF 236
Cdd:COG3833   190 RIILPLAKPILAVVALLSF 208
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 192-303 1.32e-03

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 39.73  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1514763350 192 AALSGINPDLYEAATVDGANRFKQITHITLPSMVP------IISILLILN-FGSMmnggfdqVFNLYNTmvYDSGDVIDT 264
Cdd:COG0555   157 PVLEELDPELEEAAATLGASRWQTFRRVILPLLLPalltgfALAFARALGeFGAV-------IFIAGNL--PMKTEILPL 227

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1514763350 265 YVYrIGLTQGKYSVATAIGLFLNVINFVLLVMVNSIAKK 303
Cdd:COG0555   228 LIY-LKLEEGDYAGATAIALVLLLISFLLLLLINLLQRR 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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