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Conserved domains on  [gi|1509167425|gb|AYQ22812|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Coscineuta sp. OR249]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 3.33e-93

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.94  E-value: 3.33e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   1 MTNNSMKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  81 EYMMTwekENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNtFMFTIVILSIII 160
Cdd:MTH00160   81 NLMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 241 FLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTENTWLTKHNPKKLSIILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1509167425 321 MTTMISILGLISTSTLISF 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 3.33e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.94  E-value: 3.33e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   1 MTNNSMKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  81 EYMMTwekENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNtFMFTIVILSIII 160
Cdd:MTH00160   81 NLMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 241 FLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTENTWLTKHNPKKLSIILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1509167425 321 MTTMISILGLISTSTLISF 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 9.19e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 104.32  E-value: 9.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  24 SNSWLGVWMGLEINLLSLIPLLT-NNKNMKMNESSIKYFIVQVMASTMLLFSIILI--------------QMEYMMTWEK 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  89 ENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITL-MTWQKIAPMMIM-------SYCIKMNTFMFTIVILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISALTV----SENNWELYFLIYSLLSLIIVLMF-----KQMNLFFLNQIYSTTG 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1509167425 232 MKTEIKFTMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 5.33e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 90.56  E-value: 5.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   8 LLFLSSLmmGTILSISSNSWLGVWMGLEINLLSLIPLLT-NNKNMKMNESSIKYFIVQVMASTMLLFSIILIqmeYMMT- 85
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLL---YGATg 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  86 -----------WEKENIPSM------MISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIM-------- 140
Cdd:COG1007   182 slnlagiaaalAAGGANSPLlllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveaf 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 141 -SYCIKMNTFMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMISALTV-SENNWE---LYFLIYSLLSL---IIV 212
Cdd:COG1007   262 pGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLFMNLgafAVI 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 213 LMFKQmNLFFLNQIYSTTGMKTEIKFTMFLSLLSLGGLP---PFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYY 289
Cdd:COG1007   342 LLLSR-KGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAgipPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYY 420


                  ...
gi 1509167425 290 LRI 292
Cdd:COG1007   421 LRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-339 2.09e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.77  E-value: 2.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  17 GTILSISSNSWLGVWMGLEINLLSLIPLLT-NNKNMKMNESSIKYFIVQVMASTMLLFSIILIQ-----------MEYMM 84
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYgftgslnfedlLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  85 TWEKENIPSMM----ISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAP----MMIMSYCIKMNT-----FMF 151
Cdd:TIGR01770 194 NGMLNISLLLLgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavfLRLFLYILFGFSeawqiFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 152 TIVILSIIIGALGGLNQTSLRQIMAYSSISHLGW-MISALTVSENNWE---LYFLIYSLLSL---IIVLMFKQMNLFFLN 224
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLgafGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 225 QIYSTTGMKTE---IKFTMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRIsfsAVIMSY 301
Cdd:TIGR01770 354 YISDFAGLFKTnpiLAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVMYF 430

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1509167425 302 tentwltkHNPKKLSIILPMTTMISILGLISTSTLISF 339
Cdd:TIGR01770 431 --------DKPERRIPSNPQSKAQSLLLSISALFILFL 460
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 3.33e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.94  E-value: 3.33e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   1 MTNNSMKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  81 EYMMTwekENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNtFMFTIVILSIII 160
Cdd:MTH00160   81 NLMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 241 FLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTENTWLTKHNPKKLSIILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1509167425 321 MTTMISILGLISTSTLISF 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 3-340 1.50e-57

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 189.76  E-value: 1.50e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   3 NNSMKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQM-- 80
Cdd:MTH00041    2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWls 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  81 -EYMMTWEKENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFTIV--ILS 157
Cdd:MTH00041   82 gSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILcgILS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 158 IIIGALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIK 237
Cdd:MTH00041  162 VLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISA 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 238 FTMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTEN-----TWLTKHNP 312
Cdd:MTH00041  242 FLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHsislfSWRNSGNI 321

                         330       340
                  ....*....|....*....|....*...
gi 1509167425 313 KKLSIILPMTTMISILGLISTSTLISFY 340
Cdd:MTH00041  322 TVYGVILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 7-327 3.43e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 188.88  E-value: 3.43e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   7 KLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIIliqMEYMMT- 85
Cdd:MTH00112    6 KLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSST---TNAWNTg 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  86 -WE----KENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPM--MIMSYCIKMNTFMFTIVILSI 158
Cdd:MTH00112   83 qWDitqlTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLtlLLMTSNSLNPTLLLTLAILST 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 159 IIGALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKF 238
Cdd:MTH00112  163 LIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNT 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 239 TMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVI-----MSYTENTWLTKHNPK 313
Cdd:MTH00112  243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTItlppnTTNMMMKWRTKPKKN 322

                         330
                  ....*....|....
gi 1509167425 314 KLSIILPMTTMISI 327
Cdd:MTH00112  323 TLTATLTTLSTLLL 336
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 1.03e-56

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 187.44  E-value: 1.03e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  10 FLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIIL---IQMEYMMTW 86
Cdd:MTH00070    9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  87 EKENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPM--MIMSYCIKMNTFMFTIVILSIIIGALG 164
Cdd:MTH00070   89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMalLIQISHLLNSNLLIIMGLLSTLIGGWG 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 165 GLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIySTTGMKTEIKFTMFLSL 244
Cdd:MTH00070  169 GLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKL-SSSWSKNPTLTSMMMLT 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 245 LSLGGLPPFL-GFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSY--TENTWLTKHNPKKLSIILPM 321
Cdd:MTH00070  248 LLSLGGLPPTtGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSpnTSNSKLYWRFKNKTNNLLSL 327

                         330
                  ....*....|....*....
gi 1509167425 322 TTMISILGLISTSTLISFY 340
Cdd:MTH00070  328 TIILSLMLLPITPTILNLF 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-340 3.35e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 181.20  E-value: 3.35e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   8 LLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQM---EYMM 84
Cdd:MTH00105    7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMysgQWTI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  85 TWEKENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIM---SYCIKMNTFMfTIVILSIIIG 161
Cdd:MTH00105   87 TKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILyqiSPSINPNLLL-TLAILSILIG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 162 ALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTMF 241
Cdd:MTH00105  166 GWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLIL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 242 LSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFS-AVIMSYTENTWLTK--HNPKKLSII 318
Cdd:MTH00105  246 LTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTNNMKMKwqFENTKPMTL 325

                         330       340
                  ....*....|....*....|..
gi 1509167425 319 LPMTTMISILGLISTSTLISFY 340
Cdd:MTH00105  326 LPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-339 3.15e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 170.76  E-value: 3.15e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   9 LFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIIL---IQMEYMMT 85
Cdd:MTH00135    8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTnawLTGQWDIQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  86 WEKENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFTIV-ILSIIIGALG 164
Cdd:MTH00135   88 QMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLgLTSTLVGGWG 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 165 GLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIySTTGMKTEIKFTMFLSL 244
Cdd:MTH00135  168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTL-ATSWTKAPALTALTPLI 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 245 LSLGGLPPFL-GFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFS-AVIMSYTENTWLT--KHNPKKLSIILP 320
Cdd:MTH00135  247 LLSLGGLPPLtGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAmTLTISPNTLNGTTpwRLPSTQLTLPLA 326

                         330
                  ....*....|....*....
gi 1509167425 321 MTTMISILGLISTSTLISF 339
Cdd:MTH00135  327 ISTTATLMLLPLTPAILAL 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-339 1.00e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 166.68  E-value: 1.00e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   6 MKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQM---EY 82
Cdd:MTH00200    5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWtsgQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  83 MMTWEKENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMS--YCIKMNTFMFTIVILSIII 160
Cdd:MTH00200   85 GISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTM 240
Cdd:MTH00200  165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 241 FLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVI-----MSYTENTWLTKHNPKKL 315
Cdd:MTH00200  245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLtlspnQINMMSSWRTKSNSNLL 324

                         330       340
                  ....*....|....*....|....
gi 1509167425 316 siiLPMTTMISILGLISTSTLISF 339
Cdd:MTH00200  325 ---VGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-328 1.23e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 166.00  E-value: 1.23e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   9 LFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQMEYMMtwek 88
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL---- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  89 ENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFTIVILSIIIGALGGLNQ 168
Cdd:MTH00197   78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 169 TSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTMFLSLLSLG 248
Cdd:MTH00197  158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 249 GLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTENTWLTKHNPKKLSIILPMTTMISIL 328
Cdd:MTH00197  238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMMLPLL 317
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-321 2.23e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 165.44  E-value: 2.23e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   5 SMKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSiILIQMEYMM 84
Cdd:MTH00144    4 PSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFG-SLIMYNLSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  85 TWEKenipSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFTIVILSI---IIG 161
Cdd:MTH00144   83 SWFS----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVlsaLVG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 162 ALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTMF 241
Cdd:MTH00144  159 SIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIIS 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 242 lSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTENTWLTKHNPKKLSIILPM 321
Cdd:MTH00144  239 -LLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISLNL 317
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 8-323 2.26e-47

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 162.64  E-value: 2.26e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   8 LLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQMEYMMTwe 87
Cdd:MTH00011    9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLL-- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  88 kENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMN--TFMFTIVILSIIIGALGG 165
Cdd:MTH00011   87 -KNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNilPMMTSMAAMSALAGGLGG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 166 LNQTSLRQIMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLNQIYSTTGMKTEIKFTMFLSLL 245
Cdd:MTH00011  166 MNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLL 245

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1509167425 246 SLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRISFSAVIMSYTENTWLTKHNPKKLSIILPMTT 323
Cdd:MTH00011  246 SLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSSLKSAPYEPKTKILISMCT 323
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 9.19e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 104.32  E-value: 9.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  24 SNSWLGVWMGLEINLLSLIPLLT-NNKNMKMNESSIKYFIVQVMASTMLLFSIILI--------------QMEYMMTWEK 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  89 ENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITL-MTWQKIAPMMIM-------SYCIKMNTFMFTIVILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISALTV----SENNWELYFLIYSLLSLIIVLMF-----KQMNLFFLNQIYSTTG 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1509167425 232 MKTEIKFTMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-292 1.96e-21

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 94.50  E-value: 1.96e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   8 LLFLSSLMmGTILSISSNSWLGVWMGLEINLLSLIPLL-TNNKNMKMNESSIKYFIVQVMASTMLLFSIILI-------- 78
Cdd:PRK05777  107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLYALAaLRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLygatgsls 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  79 --QMEYMMTWEKENIPSM-----MISSSLLLKIGAAPFHFWFPEV-----------MSASSWINCITLMTwqKIAPMMIM 140
Cdd:PRK05777  186 faGIAKALADGSGNSLLLlfglvFLLVGLAFKLSAVPFHMWTPDVyegaptpvtafLATAPKIAAFAVLL--RLLVVAFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 141 SYCIKMNTFMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMISALTVSENNWE----LYFLIYSLLSL----IIV 212
Cdd:PRK05777  264 GLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsavlFYLLAYLFMTLgafgVIS 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 213 LMFKQmnLFFLNQIYSTTGMKTEIKFTMFLSLLSLGGLP---PFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYY 289
Cdd:PRK05777  344 LLRRK--GGEAESISDFAGLSKRSPLLAAVMTIFMLSLAgipPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYY 421


                  ...
gi 1509167425 290 LRI 292
Cdd:PRK05777  422 LRV 424
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 5.33e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 90.56  E-value: 5.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   8 LLFLSSLmmGTILSISSNSWLGVWMGLEINLLSLIPLLT-NNKNMKMNESSIKYFIVQVMASTMLLFSIILIqmeYMMT- 85
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLL---YGATg 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  86 -----------WEKENIPSM------MISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIM-------- 140
Cdd:COG1007   182 slnlagiaaalAAGGANSPLlllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveaf 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 141 -SYCIKMNTFMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMISALTV-SENNWE---LYFLIYSLLSL---IIV 212
Cdd:COG1007   262 pGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLFMNLgafAVI 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 213 LMFKQmNLFFLNQIYSTTGMKTEIKFTMFLSLLSLGGLP---PFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYY 289
Cdd:COG1007   342 LLLSR-KGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAgipPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYY 420


                  ...
gi 1509167425 290 LRI 292
Cdd:COG1007   421 LRV 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-292 7.94e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.93  E-value: 7.94e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  16 MGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKN-MKMNESSIKYFIVQVMASTMLLFSIIL---------IQMEYMMT 85
Cdd:MTH00196    4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGsGYSAEAGLKYFVLGALSSGLFLFGCALlcgttgglhLSYINLVL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  86 WEKEN-------IPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFTIVILSI 158
Cdd:MTH00196   84 NSGQSfssvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 159 IIGALGGLNQTSLRQIMAYSSISHLGWMIsaLTVSENNWE------LYFLIYSLLSLIIVLMFKQMNlFFLNQIYSTTGM 232
Cdd:MTH00196  164 FVGAIGALNQTKIKRLLAYSGIGHMGFVL--WGIEIGSFEsiqaslVYLFIYIIMSICVFSIILALN-VYKNLIIEFSGL 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1509167425 233 KTEIKF---TMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRI 292
Cdd:MTH00196  241 SRRLPIlaiTLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-339 2.09e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.77  E-value: 2.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  17 GTILSISSNSWLGVWMGLEINLLSLIPLLT-NNKNMKMNESSIKYFIVQVMASTMLLFSIILIQ-----------MEYMM 84
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYgftgslnfedlLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  85 TWEKENIPSMM----ISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAP----MMIMSYCIKMNT-----FMF 151
Cdd:TIGR01770 194 NGMLNISLLLLgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavfLRLFLYILFGFSeawqiFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 152 TIVILSIIIGALGGLNQTSLRQIMAYSSISHLGW-MISALTVSENNWE---LYFLIYSLLSL---IIVLMFKQMNLFFLN 224
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLgafGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 225 QIYSTTGMKTE---IKFTMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRIsfsAVIMSY 301
Cdd:TIGR01770 354 YISDFAGLFKTnpiLAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVMYF 430

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1509167425 302 tentwltkHNPKKLSIILPMTTMISILGLISTSTLISF 339
Cdd:TIGR01770 431 --------DKPERRIPSNPQSKAQSLLLSISALFILFL 460
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 3.50e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 85.07  E-value: 3.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  16 MGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKN-MKMNESSIKYFIVQVMASTMLLFSIILIqmeYMMTWEK------ 88
Cdd:MTH00199  108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDsAYSTEAGLKYFVLGAVSSGLFLFGCALL---YGLTGETsiqgin 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  89 ----ENIPSMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFTIVILSIIIGALG 164
Cdd:MTH00199  185 siltGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIG 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 165 GLNQTSLRQIMAYSSISHLGWMISALTVSENNW----ELYFLIYSLLSLIIVLMFKQMNLF--FLNQIYSTTGMKTEIKF 238
Cdd:MTH00199  265 ALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESiqasLIYMIIYVIMSICSFSIILSLKLTkgLIVEVSGLSRKNPVIAL 344

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1509167425 239 TMFLSLLSLGGLPPFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRI 292
Cdd:MTH00199  345 TLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-198 3.52e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 70.27  E-value: 3.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  16 MGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMN---------ESSIKYFIVQVMASTMLLFSIIL----IQMEY 82
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALyfgfTGNEG 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  83 MM------TWEKENIP-------SMMISSSLLLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTF 149
Cdd:MTH00198  279 MLgtilsaTLETTNIElrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1509167425 150 MFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMIsaLTVSENNWE 198
Cdd:MTH00198  359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL--IGVSAGTYE 405
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-292 1.22e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 62.09  E-value: 1.22e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  10 FLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIQ-------MEY 82
Cdd:COG0651   112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYgatgtlnMAD 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  83 MMTWEKENIPSMMISSSLLL------KIGAAPFHFWFPEVMS-ASSWINCI--TLMTwqKIAPMMIM---------SYCI 144
Cdd:COG0651   192 LAARLAELDPGLLLAAFALLlvgfgiKAALFPLHFWLPDAYPaAPSPVSALlsGLLT--KVGVYAILrvltllfgaDPAL 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 145 KMNTFMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMISAL---TVSENNWELYFLIY-----SLLSLIIVLMFK 216
Cdd:COG0651   270 FLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLglgTPLGLAGALFHLLNhalakALLFLAAGAIER 349

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1509167425 217 QMNLFFLNQIystTGMKTEIKFTMFLSLLSLGGLP---PFLGFLPKWIVMQSLLENNLTTIMVIMVMLTTITLYYYLRI 292
Cdd:COG0651   350 ATGTRDLDKL---GGLGKRMPLTAAAFLIGALALAglpPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-193 3.45e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 51.64  E-value: 3.45e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  55 ESSIKYFIVQVMASTMLLFSIILIQMEY-------------MMTWEKENIPSMMISSSLLLKIGAAPFHFWFPEVMSAS- 120
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIALLYGQYgtlnmaylavkmsENPTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPAAp 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 121 SWINCITLMTWQ-KIAPMM-----IMSYCIKMNTFMFTIVI---LSIIIGALGGLNQTSLRQIMAYSSISHLGWMISALT 191
Cdd:PRK08376  252 SSISAMLLVIKQaGLYALArvlfsIYGPAINLATVGWVIIIlgcLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLG 331


                  ..
gi 1509167425 192 VS 193
Cdd:PRK08376  332 VG 333
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-187 4.75e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.03  E-value: 4.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  34 LEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILIqmeYMMTWE------KENIPSM--------MISSS 99
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLL---YGVTGTlnmadlAGALAENptvvtafgFVLLA 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 100 LLLKIGAAPFHFWFPEVMS-ASSWINCITLMTWQKIAPMMIM-----------SYCIKMNTFMFTIVILSIIIGALGGLN 167
Cdd:PRK08375  212 LALKAAVFPLHTWLPRAYPaAPPVVTALLSGLVTKVAVYALIriyftvfggdfRFALGLGWLLAVLALLSMLVGSLAALG 291

                         170       180
                  ....*....|....*....|
gi 1509167425 168 QTSLRQIMAYSSISHLGWMI 187
Cdd:PRK08375  292 QDDVKRVLAYSTVSQMGYIL 311
PRK12650 PRK12650
DUF4040 family protein;
94-192 3.89e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 45.42  E-value: 3.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  94 MMISSSLLLKIGAAPFHFWFPEVMSASSWINcitlmTWQKIAPMM------------IMSYCIKMNTFMFTIVILSIIIG 161
Cdd:PRK12650  212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVS-----AFLHAAAVVkagiylllrfspVFHDVAVWNWLLIIVGMITALMG 286

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1509167425 162 ALGGLNQTSLRQIMAYSSISHLGWMISALTV 192
Cdd:PRK12650  287 AVFAVQKTDLKKLTAYSTVSQLGWIVATIGV 317
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 8-187 2.41e-04

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 42.62  E-value: 2.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   8 LLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKmneSSIKYFIVQVMASTMLLFSIILIQMEYMMTWE 87
Cdd:TIGR01972 112 LLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIY---AAMKFFLYTLAGSLLMLLAILGLYFLGGGTFD 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  88 KENIPSMMISSS----LLLKIGAA--------PFHFWFPEVMSASSWINCITLM-TWQKIAPMMIMSYCIKM-----NTF 149
Cdd:TIGR01972 189 LLELLNLPLPFGvqtwLFLAFFIAfavkvplfPLHTWLPDAHVEAPTAGSVILAgVLLKMGTYGFLRFNLPLfpdasLYF 268

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1509167425 150 MFTIVILS---IIIGALGGLNQTSLRQIMAYSSISHLGWMI 187
Cdd:TIGR01972 269 APVLAALGviaIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
54-209 2.78e-04

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 42.73  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  54 NESSIKYFIVQVMASTMLLFSIILIqmeYMMTWEKENI----PSMMISSSLLL-------------KIGAAPFHFWFPEV 116
Cdd:PRK02504  160 NEAALKYLLIGAASSAIFLYGSSLL---YGLSGGSTQLsaiaLALITSPSLGLalalvfviagiafKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 117 MSASSWINCITLMTWQKIA----PMMIMSYCIKMNT----FMFTIV-ILSIIIGALGGLNQTSLRQIMAYSSISHLGW-M 186
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDeqwkLLFTALaILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvM 316

                         170       180
                  ....*....|....*....|....*.
gi 1509167425 187 ISALTVSENNWE---LYFLIYSLLSL 209
Cdd:PRK02504  317 IGLVAGTEAGYAsmvFYLLAYLFMNL 342
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-340 3.96e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 42.11  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425   3 NNSMKLLFLSSLMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNESSIKYFIVQVMASTMLLFSIILI---- 78
Cdd:PRK06589  114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVILiytk 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  79 --QMEYMMTWEKENIPSMMISSSLLLKIGAA---PFHFWFPEVMSASSWINC-----------------ITLMTWQkiap 136
Cdd:PRK06589  194 tgNLDFVSGGLFSKNQSIILLLMFIYGIAKTaifPVHSWLPAAMVAHYPVSAllhavivvktglfciykILLYIFG---- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 137 MMIMSYCIKMNTFMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMISALTV----SENNWELYFLIYSLLSL-II 211
Cdd:PRK06589  270 LSYLQRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFIltpkALGAAILHLVSHSFAKIcLF 349

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 212 VLMFKQMNLFFLNQIYSTTGMKTEIKFTMFLSLLSLGGLP---PFLGFLPKWIVMQSLLENNLTTIMVIMVML----TTI 284
Cdd:PRK06589  350 YSMGSIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIgipIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSIL 429

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1509167425 285 TLYYYLRISFSAVIMSYTENTWLTKhnpkklsiILPMTTMISILGLISTSTLISFY 340
Cdd:PRK06589  430 SALYLLKILSSIYKPSLSENSFITK--------SLPYLMQISVITCCCALTLFYFI 477
ndhB CHL00049
NADH dehydrogenase subunit 2
 103-209 1.22e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 40.37  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 103 KIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMM--------IMSYCIKMNTFMFTIV-ILSIIIGALGGLNQTSLRQ 173
Cdd:CHL00049  227 KLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASAlatrifdiPFYFSSNEWHLLLEILaILSMILGNLIAITQTSMKR 306

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1509167425 174 IMAYSSISHLGWMISALTVSENNWE-----LYFLIYSLLSL 209
Cdd:CHL00049  307 MLAYSSIGQIGYVIIGIIVGDSNDGyasmiTYMLFYIFMNL 347
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 100-190 1.54e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 40.14  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 100 LLLKIGAA------PFHFWFPEVMSA----SSWINCIT-------LMTwqKIAPMMIMSycikMNTFMFTIVI--LSIII 160
Cdd:COG1009   215 LLLLLGAFgksaqfPLHFWLPDAMEGptpvSALLHAATmvkagvyLLA--RLSPLFALS----PVWLTVVAIIgaITALF 288

                          90       100       110
                  ....*....|....*....|....*....|
gi 1509167425 161 GALGGLNQTSLRQIMAYSSISHLGWMISAL 190
Cdd:COG1009   289 AALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-224 2.55e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 39.08  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  14 LMMGTILSISSNSWLGVWMGLEINLLSLIPLLTNNKNMKMNessikYFIVQVMASTMLLFSIILIQMEYMMtwekenips 93
Cdd:MTH00091    3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQFLILM--------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425  94 mmisssllLKIGAAPFHFWFPEVMSASSWINCITLMTWQKIAPMMIMSYCIKMNTFMFtiVILSIIIGALGGLNQTSLRQ 173
Cdd:MTH00091   69 --------MKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFL--LLFGLLICFFQMFLLKSYKN 138

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1509167425 174 IMAYSSISHLGWMISALTVSENNWELYFLIYSLLSLIIVLMFKQMNLFFLN 224
Cdd:MTH00091  139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFV 189
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 146-193 3.33e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 39.18  E-value: 3.33e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1509167425 146 MNTFMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLGWMISALTVS 193
Cdd:PRK12665  272 LDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALS 319
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 100-184 4.19e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 39.13  E-value: 4.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1509167425 100 LLLKIGAA-------PFHFWFPEVMSA----SSWINCITlMTWQKIAPMMIMSYCIKMNTFMFTIVIL----SIIIGALG 164
Cdd:PRK12647  198 LLLVLGGAftksaqfPFHFWLPNAMEAptpvSAYLHSAT-MVKAGIYLLARLNPVLGGTPLWQTILPLfgglTMLTGALL 276

                          90       100
                  ....*....|....*....|
gi 1509167425 165 GLNQTSLRQIMAYSSISHLG 184
Cdd:PRK12647  277 AVRQTDLKLILAYSTVSALG 296
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 149-184 4.52e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 38.52  E-value: 4.52e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1509167425 149 FMFTIVILSIIIGALGGLNQTSLRQIMAYSSISHLG 184
Cdd:COG1008   277 LLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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