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Conserved domains on  [gi|149933968|gb|ABR40666|]
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conserved hypothetical protein [Phocaeicola vulgatus ATCC 8482]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PepSY_like super family cl24241
Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is ...
 49-142 8.59e-09

Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is probably periplasmic. Members are found predominantly in microbes of the human gut and oral cavity. Structurally, one member of this family is found to show similarity to the beta-lactamase-inhibitor PepSY proteins, so the overall function may be inhibitory. There are tandem repeats of the domain on many family members.


The actual alignment was detected with superfamily member pfam11396:

Pssm-ID: 431867  Cd Length: 83  Bit Score: 49.96  E-value: 8.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149933968   49 YYVASFTQNgfeKEVWMNGNAQWVMTN---TDLqTTDQLTPNVYNDFTLSPYAmwtATNVNLIEFPKrtTLYVITVNlnn 125
Cdd:pfam11396   1 YYDVDFTDG---TEVEFDKKGNWKETEckyTDV-PLDILPAAVAKYFKASNYP---DEDVVKIERPK--TGYEIELE--- 68

                          90
                  ....*....|....*..
gi 149933968  126 ssATKQLFYTLNGRLLQ 142
Cdd:pfam11396  69 --NGVELYFDPKGNLLK 83
 
Name Accession Description Interval E-value
PepSY_like pfam11396
Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is ...
 49-142 8.59e-09

Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is probably periplasmic. Members are found predominantly in microbes of the human gut and oral cavity. Structurally, one member of this family is found to show similarity to the beta-lactamase-inhibitor PepSY proteins, so the overall function may be inhibitory. There are tandem repeats of the domain on many family members.


Pssm-ID: 431867  Cd Length: 83  Bit Score: 49.96  E-value: 8.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149933968   49 YYVASFTQNgfeKEVWMNGNAQWVMTN---TDLqTTDQLTPNVYNDFTLSPYAmwtATNVNLIEFPKrtTLYVITVNlnn 125
Cdd:pfam11396   1 YYDVDFTDG---TEVEFDKKGNWKETEckyTDV-PLDILPAAVAKYFKASNYP---DEDVVKIERPK--TGYEIELE--- 68

                          90
                  ....*....|....*..
gi 149933968  126 ssATKQLFYTLNGRLLQ 142
Cdd:pfam11396  69 --NGVELYFDPKGNLLK 83
 
Name Accession Description Interval E-value
PepSY_like pfam11396
Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is ...
 49-142 8.59e-09

Putative beta-lactamase-inhibitor-like, PepSY-like; This family of bacterial proteins is probably periplasmic. Members are found predominantly in microbes of the human gut and oral cavity. Structurally, one member of this family is found to show similarity to the beta-lactamase-inhibitor PepSY proteins, so the overall function may be inhibitory. There are tandem repeats of the domain on many family members.


Pssm-ID: 431867  Cd Length: 83  Bit Score: 49.96  E-value: 8.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149933968   49 YYVASFTQNgfeKEVWMNGNAQWVMTN---TDLqTTDQLTPNVYNDFTLSPYAmwtATNVNLIEFPKrtTLYVITVNlnn 125
Cdd:pfam11396   1 YYDVDFTDG---TEVEFDKKGNWKETEckyTDV-PLDILPAAVAKYFKASNYP---DEDVVKIERPK--TGYEIELE--- 68

                          90
                  ....*....|....*..
gi 149933968  126 ssATKQLFYTLNGRLLQ 142
Cdd:pfam11396  69 --NGVELYFDPKGNLLK 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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