NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1491220464|gb|RLG97398|]
View 

hypothetical protein DRO27_00080 [Candidatus Bathyarchaeota archaeon]

Protein Classification

nucleoside/nucleotide kinase family protein( domain architecture ID 106737)

nucleoside/nucleotide kinase family protein may catalyze the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NK super family cl17190
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 3-74 1.04e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


The actual alignment was detected with superfamily member TIGR00152:

Pssm-ID: 450170  Cd Length: 190  Bit Score: 38.14  E-value: 1.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1491220464   3 IAFAGEMTSGKTTAAEYLSEVYGFGILsFADKLkynlidigvpIKVLFEEKTEASRTLMQVYGEVMRDYDPE 74
Cdd:TIGR00152   2 IALTGGIGSGKSTVLQYLADKYHFPVI-DADKI----------AHQVVEPGQPAYHAIADHFGANILNQDGE 62
NK super family cl17190
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 58-167 1.50e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


The actual alignment was detected with superfamily member PHA02575:

Pssm-ID: 450170  Cd Length: 227  Bit Score: 37.75  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491220464  58 RTLMQVYG-EVMRDYDPEYWVDYILEGVSTGEGMLTEAHAVDDMRYLNEGEVLKEEGFHLVCITKKGpapmwSPTHEHAS 136
Cdd:PHA02575  121 RRLMQTLGtDIVVNFNKMYWVKLFALKYLDKFKSDYDYFIVTDVRQDHEMELVRAMGATVIHVVRDT-----GLVDTHST 195

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1491220464 137 ENEWRDIDFDyHISAQEGDLVDLFGQLDDMI 167
Cdd:PHA02575  196 EAGLPIQPGD-IVITNNGTLEELKSKILNLI 225
 
Name Accession Description Interval E-value
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 3-74 1.04e-03

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 38.14  E-value: 1.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1491220464   3 IAFAGEMTSGKTTAAEYLSEVYGFGILsFADKLkynlidigvpIKVLFEEKTEASRTLMQVYGEVMRDYDPE 74
Cdd:TIGR00152   2 IALTGGIGSGKSTVLQYLADKYHFPVI-DADKI----------AHQVVEPGQPAYHAIADHFGANILNQDGE 62
1 PHA02575
deoxynucleoside monophosphate kinase; Provisional
 58-167 1.50e-03

deoxynucleoside monophosphate kinase; Provisional


Pssm-ID: 222885  Cd Length: 227  Bit Score: 37.75  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491220464  58 RTLMQVYG-EVMRDYDPEYWVDYILEGVSTGEGMLTEAHAVDDMRYLNEGEVLKEEGFHLVCITKKGpapmwSPTHEHAS 136
Cdd:PHA02575  121 RRLMQTLGtDIVVNFNKMYWVKLFALKYLDKFKSDYDYFIVTDVRQDHEMELVRAMGATVIHVVRDT-----GLVDTHST 195

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1491220464 137 ENEWRDIDFDyHISAQEGDLVDLFGQLDDMI 167
Cdd:PHA02575  196 EAGLPIQPGD-IVITNNGTLEELKSKILNLI 225
 
Name Accession Description Interval E-value
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 3-74 1.04e-03

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 38.14  E-value: 1.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1491220464   3 IAFAGEMTSGKTTAAEYLSEVYGFGILsFADKLkynlidigvpIKVLFEEKTEASRTLMQVYGEVMRDYDPE 74
Cdd:TIGR00152   2 IALTGGIGSGKSTVLQYLADKYHFPVI-DADKI----------AHQVVEPGQPAYHAIADHFGANILNQDGE 62
1 PHA02575
deoxynucleoside monophosphate kinase; Provisional
 58-167 1.50e-03

deoxynucleoside monophosphate kinase; Provisional


Pssm-ID: 222885  Cd Length: 227  Bit Score: 37.75  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491220464  58 RTLMQVYG-EVMRDYDPEYWVDYILEGVSTGEGMLTEAHAVDDMRYLNEGEVLKEEGFHLVCITKKGpapmwSPTHEHAS 136
Cdd:PHA02575  121 RRLMQTLGtDIVVNFNKMYWVKLFALKYLDKFKSDYDYFIVTDVRQDHEMELVRAMGATVIHVVRDT-----GLVDTHST 195

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1491220464 137 ENEWRDIDFDyHISAQEGDLVDLFGQLDDMI 167
Cdd:PHA02575  196 EAGLPIQPGD-IVITNNGTLEELKSKILNLI 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH