NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1490892732|gb|RLE27775|]
View 

protoheme IX farnesyltransferase [Acidobacteria bacterium]

Protein Classification

protoheme IX farnesyltransferase( domain architecture ID 10195468)

protoheme IX farnesyltransferase acts in step 1 of the conversion protoheme IX to heme O in heme O biosynthesis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 15-284 8.88e-104

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


:

Pssm-ID: 260120  Cd Length: 271  Bit Score: 304.75  E-value: 8.88e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  15 LEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRA 94
Cdd:cd13957     1 LELTKPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  95 QIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTPMKIRTSA-NTLVGAVVGAVPPVIGWTAYSGRIEIGALILF 173
Cdd:cd13957    81 LIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPlNTVIGGIAGAIPPLIGWAAATGSLDLGAWLLF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 174 GILFTWQVPHFLALAWMYREDYARGGFQMLPAVDALGRfTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFA 253
Cdd:cd13957   161 LILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERR-TKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLYFL 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1490892732 254 VAALPFYRERTRLTARRLFLASIIYLPLLLI 284
Cdd:cd13957   240 YLAIKLYRSPDDKWARKLFFASLIYLPLLFL 270
 
Name Accession Description Interval E-value
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 15-284 8.88e-104

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 304.75  E-value: 8.88e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  15 LEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRA 94
Cdd:cd13957     1 LELTKPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  95 QIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTPMKIRTSA-NTLVGAVVGAVPPVIGWTAYSGRIEIGALILF 173
Cdd:cd13957    81 LIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPlNTVIGGIAGAIPPLIGWAAATGSLDLGAWLLF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 174 GILFTWQVPHFLALAWMYREDYARGGFQMLPAVDALGRfTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFA 253
Cdd:cd13957   161 LILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERR-TKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLYFL 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1490892732 254 VAALPFYRERTRLTARRLFLASIIYLPLLLI 284
Cdd:cd13957   240 YLAIKLYRSPDDKWARKLFFASLIYLPLLFL 270
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
 14-289 3.33e-100

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 296.66  E-value: 3.33e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  14 YLEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGR 93
Cdd:COG0109    19 YLALTKPRIILLLLFTALAGMLLAAGGLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDALMKRTKNRPLPTGRISPRE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  94 AQIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTP-MKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALIL 172
Cdd:COG0109    99 ALIFGLVLGVLGLALLALFVNPLAALLGLLGIFFYVVVYTLwLKRRTPQNIVIGGAAGAMPPLIGWAAVTGSLSLEALLL 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 173 FGILFTWQVPHFLALAWMYREDYARGGFQMLPAVDAlGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAF 252
Cdd:COG0109   179 FLIIFLWTPPHFWALALKRRDDYARAGVPMLPVVKG-ERRTKRQILLYTLLLVPVSLLPYLLGMAGLIYLVVALVLGAWF 257

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1490892732 253 AVAALPFYRERTRLTARRLFLASIIYLPLLLISMVGD 289
Cdd:COG0109   258 LYLAVRLYRRPDRKWARKLFKFSILYLTLLFLALLVD 294
PLN02776 PLN02776
prenyltransferase
 17-286 1.60e-97

prenyltransferase


Pssm-ID: 215415  Cd Length: 341  Bit Score: 291.26  E-value: 1.60e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  17 MSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQI 96
Cdd:PLN02776    1 LSKARLSALVVATSGAGFVLGSGEAIDLPGLGWTCAGTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISVPHAVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  97 YGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGIL 176
Cdd:PLN02776   81 WAVVVGAAGVALLAYKTNMLTAGLGAGNILLYAFVYTPLKQIHPANTWVGAVVGAIPPLMGWAAASGQLDAGAMVLAAAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 177 FTWQVPHFLALAWMYREDYARGGFQMLPAVDALGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFAVAA 256
Cdd:PLN02776  161 YFWQMPHFMALAYMCRDDYAAGGYRMLSLADATGRRTALVALRNCLYLAPLGFLAYDWGVTSSPFALEAALLTAYLAASA 240

                         250       260       270
                  ....*....|....*....|....*....|
gi 1490892732 257 LPFYRERTRLTARRLFLASIIYLPLLLISM 286
Cdd:PLN02776  241 ASFYREPTNANARKMFHGSLLYLPAFMALL 270
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
 12-287 1.14e-79

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 243.69  E-value: 1.14e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  12 GMYLEMSKARLSAMVVFSTIAGYLLSSRGA-GHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMP 90
Cdd:TIGR01473   1 KDYLQLTKPRIISLLLITAFAGMWLAPGGAlVNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTGRIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  91 RGRAQIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYT-PMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGA 169
Cdd:TIGR01473  81 PREALAFGLLLGVLGVAILAAFVNPLAALLGLFGIFFYVIVYTiWLKRRTPQNTVIGGFAGAVPPLIGWAAVTGSISLGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 170 LILFGILFTWQVPHFLALAWMYREDYARGGFQMLPAVDALgRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALG 249
Cdd:TIGR01473 161 WLLFAIIFLWQPPHFWALALKYKDDYRAAGIPMLPVVKGE-RITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATLLG 239

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1490892732 250 LAFAVAALPFYRERT-RLTARRLFLASIIYLPLLLISMV 287
Cdd:TIGR01473 240 ALFLYLAFKFYRDPTdRKKARKLFKFSLIYLALLFVALL 278
UbiA pfam01040
UbiA prenyltransferase family;
26-273 9.95e-43

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 147.76  E-value: 9.95e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  26 VVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQIYGWASSVAG 105
Cdd:pfam01040   1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 106 VVLLAtFVNLLTSALALAVILVYTLVYTPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGILFTWQVPHFL 185
Cdd:pfam01040  81 LLLLL-LLNPLTALLGLAALLLYVLYTLRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 186 ALAWMYREDYARGGFQMLPAVdaLGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFAVAALPFYRERTR 265
Cdd:pfam01040 160 ANDLRDREDDRKAGIKTLPVV--LGRKAARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDP 237


                  ....*...
gi 1490892732 266 LTARRLFL 273
Cdd:pfam01040 238 KKDAKAFF 245
 
Name Accession Description Interval E-value
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 15-284 8.88e-104

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 304.75  E-value: 8.88e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  15 LEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRA 94
Cdd:cd13957     1 LELTKPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  95 QIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTPMKIRTSA-NTLVGAVVGAVPPVIGWTAYSGRIEIGALILF 173
Cdd:cd13957    81 LIFGLVLGILGLALLALFVNPLTALLGLLGIFLYVFVYTPLKKRTTPlNTVIGGIAGAIPPLIGWAAATGSLDLGAWLLF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 174 GILFTWQVPHFLALAWMYREDYARGGFQMLPAVDALGRfTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFA 253
Cdd:cd13957   161 LILFLWQPPHFWALAILYRDDYARAGIPMLPVVKGERR-TKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLYFL 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1490892732 254 VAALPFYRERTRLTARRLFLASIIYLPLLLI 284
Cdd:cd13957   240 YLAIKLYRSPDDKWARKLFFASLIYLPLLFL 270
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
 14-289 3.33e-100

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 296.66  E-value: 3.33e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  14 YLEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGR 93
Cdd:COG0109    19 YLALTKPRIILLLLFTALAGMLLAAGGLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDALMKRTKNRPLPTGRISPRE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  94 AQIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTP-MKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALIL 172
Cdd:COG0109    99 ALIFGLVLGVLGLALLALFVNPLAALLGLLGIFFYVVVYTLwLKRRTPQNIVIGGAAGAMPPLIGWAAVTGSLSLEALLL 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 173 FGILFTWQVPHFLALAWMYREDYARGGFQMLPAVDAlGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAF 252
Cdd:COG0109   179 FLIIFLWTPPHFWALALKRRDDYARAGVPMLPVVKG-ERRTKRQILLYTLLLVPVSLLPYLLGMAGLIYLVVALVLGAWF 257

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1490892732 253 AVAALPFYRERTRLTARRLFLASIIYLPLLLISMVGD 289
Cdd:COG0109   258 LYLAVRLYRRPDRKWARKLFKFSILYLTLLFLALLVD 294
PLN02776 PLN02776
prenyltransferase
 17-286 1.60e-97

prenyltransferase


Pssm-ID: 215415  Cd Length: 341  Bit Score: 291.26  E-value: 1.60e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  17 MSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQI 96
Cdd:PLN02776    1 LSKARLSALVVATSGAGFVLGSGEAIDLPGLGWTCAGTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISVPHAVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  97 YGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGIL 176
Cdd:PLN02776   81 WAVVVGAAGVALLAYKTNMLTAGLGAGNILLYAFVYTPLKQIHPANTWVGAVVGAIPPLMGWAAASGQLDAGAMVLAAAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 177 FTWQVPHFLALAWMYREDYARGGFQMLPAVDALGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFAVAA 256
Cdd:PLN02776  161 YFWQMPHFMALAYMCRDDYAAGGYRMLSLADATGRRTALVALRNCLYLAPLGFLAYDWGVTSSPFALEAALLTAYLAASA 240

                         250       260       270
                  ....*....|....*....|....*....|
gi 1490892732 257 LPFYRERTRLTARRLFLASIIYLPLLLISM 286
Cdd:PLN02776  241 ASFYREPTNANARKMFHGSLLYLPAFMALL 270
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 14-289 6.36e-82

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 250.06  E-value: 6.36e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  14 YLEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGR 93
Cdd:PRK04375   13 YLALTKPRVISLNLFTALGGMLLAPPGVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPRE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  94 AQIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYTP-MKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALIL 172
Cdd:PRK04375   93 ALIFGLVLGVLGFLLLGLFVNPLAAWLTLAGIFFYVVVYTLwLKRRTPQNIVIGGAAGAMPPLIGWAAVTGSLSWEALIL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 173 FGILFTWQVPHFLALAWMYREDYARGGFQMLPAVdALGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAF 252
Cdd:PRK04375  173 FLIIFLWTPPHFWALAIFRKDDYAAAGIPMLPVV-KGIRVTKRQILLYTVLLVAVSLLPVLLGMAGLLYLVVALLLGAWF 251

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1490892732 253 AVAALPFYRERTRLTARRLFLASIIYLPLLLISMVGD 289
Cdd:PRK04375  252 LYYAWRLYRKDDRKWARKLFRYSINYLTLLFVALLVD 288
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
 12-287 1.14e-79

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 243.69  E-value: 1.14e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  12 GMYLEMSKARLSAMVVFSTIAGYLLSSRGA-GHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMP 90
Cdd:TIGR01473   1 KDYLQLTKPRIISLLLITAFAGMWLAPGGAlVNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTGRIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  91 RGRAQIYGWASSVAGVVLLATFVNLLTSALALAVILVYTLVYT-PMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGA 169
Cdd:TIGR01473  81 PREALAFGLLLGVLGVAILAAFVNPLAALLGLFGIFFYVIVYTiWLKRRTPQNTVIGGFAGAVPPLIGWAAVTGSISLGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 170 LILFGILFTWQVPHFLALAWMYREDYARGGFQMLPAVDALgRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALG 249
Cdd:TIGR01473 161 WLLFAIIFLWQPPHFWALALKYKDDYRAAGIPMLPVVKGE-RITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATLLG 239

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1490892732 250 LAFAVAALPFYRERT-RLTARRLFLASIIYLPLLLISMV 287
Cdd:TIGR01473 240 ALFLYLAFKFYRDPTdRKKARKLFKFSLIYLALLFVALL 278
UbiA pfam01040
UbiA prenyltransferase family;
26-273 9.95e-43

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 147.76  E-value: 9.95e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  26 VVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQIYGWASSVAG 105
Cdd:pfam01040   1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 106 VVLLAtFVNLLTSALALAVILVYTLVYTPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGILFTWQVPHFL 185
Cdd:pfam01040  81 LLLLL-LLNPLTALLGLAALLLYVLYTLRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 186 ALAWMYREDYARGGFQMLPAVdaLGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFAVAALPFYRERTR 265
Cdd:pfam01040 160 ANDLRDREDDRKAGIKTLPVV--LGRKAARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDP 237


                  ....*...
gi 1490892732 266 LTARRLFL 273
Cdd:pfam01040 238 KKDAKAFF 245
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 25-284 1.74e-18

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 83.74  E-value: 1.74e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  25 MVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQIYGWASSVA 104
Cdd:COG0382    17 LLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGRISLREALLLAIVLLLL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 105 GVVLLAtFVNLLTSALALAVILVyTLVYTP-MKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGILFTWQVPH 183
Cdd:COG0382    97 ALALAL-LLNPLTFLLALAALAL-AWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSAWLLALAAFLWTLAY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 184 FLALAWMYREDYARGGFQMLPAVdaLGRFTART--ALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFAVAALPFY- 260
Cdd:COG0382   175 DTIYDLEDREGDRKIGIKTLAIL--FGVRDALIiaGVLYALAVLLLLLLGLLAGLGLLYLLGLLAALLLLYLSQLWLLRp 252

                         250       260
                  ....*....|....*....|....
gi 1490892732 261 RERTRLTARRLFLaSIIYLPLLLI 284
Cdd:COG0382   253 RKKDPARALKLFK-LNMLLGLLLF 275
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 30-289 4.38e-13

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 68.26  E-value: 4.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  30 TIAGYLLSSRGAG--HLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQIYGWASSVAGVV 107
Cdd:cd13959    16 ALWGLLLAAGGLPlpLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVKEALLFLAVQLLLGLA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 108 LLATFvNLLTSALALAVILVyTLVYTPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGILFTWQVPHFLAL 187
Cdd:cd13959    96 LLLQL-NPLTILLSPIALLL-VLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYLAVIFWTAGYDTIY 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 188 AWMYREDYARGGFQMLPAvdALGRFTART-ALVYALALQPLTLMVYAEGLSGITFLIIAQALGLAFAVAALpfYRERTRL 266
Cdd:cd13959   174 AHQDREDDRKIGVKSTAV--LFGDRTKLIlALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAHLLWQEHRL--DLPDPLR 249

                         250       260
                  ....*....|....*....|...
gi 1490892732 267 TARRLFLASIIYLPLLLISMVGD 289
Cdd:cd13959   250 SCLAFFLSNGWVGLLLFAGLLLD 272
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 15-284 1.96e-10

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 60.44  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  15 LEMSKARLSAMVVFSTIAGYLLSSRGAGHLD-HLLWTALGTALAAFGASIFNQILETELDAkmERTQDRPLPSGRMPRGR 93
Cdd:cd13956     1 LRLMRPYTLLYVLAPALAGAALAGAFAGPLPaLLLLALLAVFLGAGAGYALNDYTDRELDA--INKPDRPLPSGRLSPRQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  94 AQIYGWASSVAGVVLLAT--FVNLLTSALALAVILVYTLvytPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGALI 171
Cdd:cd13956    79 ALAFAAALLLVGLALALAlgPLALLLLLAGLLLGLAYSL---GLKRLKLGGWGVLGYATGLALLPGLGAVAAGGLVPLAL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 172 LFGILFTWQVPHF-LALAWMYREDYARGGFQMLPAVDALGRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALGL 250
Cdd:cd13956   156 LLALVFLLLGLGInLYNDLPDVEGDRAAGIRTLPVRLGPRRARRLAAGLLLAALILVVLLAVAGLLGPLALLALLAVALL 235

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1490892732 251 AFAVAALPFYRERTRLTARRLFLASIIYLPLLLI 284
Cdd:cd13956   236 ALRARFARADRLPALPRGFLLLAVYRLLLFAALL 269
ubiA PRK12886
prenyltransferase; Reviewed
 11-179 5.86e-08

prenyltransferase; Reviewed


Pssm-ID: 237247  Cd Length: 291  Bit Score: 53.15  E-value: 5.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  11 LGMYLEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMP 90
Cdd:PRK12886    8 LKVFLEMIKFSHTLFALPFAGIGAVLAALGLPGASQLDWILMAMVGARTAAMGFNRLIDAEIDARNPRTAGRAIPAGLIS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  91 RGRAQIYgWASSVAGVVLLATFVN---LLTSALALAVILVYTLVytpmKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEI 167
Cdd:PRK12886   88 KGSAILF-IVLSSLLMLFAAWFLNplcLYLSPPALFFLLLYSYC----KRFTALAHVVLGFCLALAPLGAWIAIRGTIEL 162

                         170
                  ....*....|..
gi 1490892732 168 GALILFGILFTW 179
Cdd:PRK12886  163 PAILLGLAVLFW 174
PT_UbiA_1 cd13964
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 30-128 1.98e-07

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260127  Cd Length: 282  Bit Score: 51.43  E-value: 1.98e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  30 TIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDAKmERtQDRPLPSGRMPRGRAQIYGWASSVAGvVLL 109
Cdd:cd13964    17 VLAGAALAGGGLGPVLRLALLLLASVLLYAAGMVLNDVFDAELDAR-ER-PERPIPSGRVSRGAALALGAGLLAAG-VAL 93

                          90       100
                  ....*....|....*....|..
gi 1490892732 110 ATFVNLLTSALAL---AVILVY 128
Cdd:cd13964    94 AALVGRLSGLVALllaAAILLY 115
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
 14-284 6.31e-07

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 49.81  E-value: 6.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  14 YLEMSKARLSAMVVFSTIAGYLLSSRGAG--HLDHLLWTALGTALAAFGASIFNQILETELDA--KmertQDRPLPSGRM 89
Cdd:cd13961     2 YLELIRPPNLLMAALAQYLGALFALGPLLslNDLELLLLFLSVFLIAAAGYIINDYFDVEIDRinK----PDRPIPSGRI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  90 PRGRAQIYGWASSVAGvVLLATFVNLLTSALALAVILV---YTLVYTPMKIrtSANTLVGAVVGAVPPVIGwtAYSGRIE 166
Cdd:cd13961    78 SRREALILSILLNALG-LILAFLLSPLALLIALLNSLLlwlYSHKLKRTPL--IGNLLVALLTGLPFLFGG--LAAGNLL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 167 IGALILFGILFtwqvphFLALAwmyRE----------DYARgGFQMLPAVdaLG-RFTARTALVYALALQPLTLMVYAEG 235
Cdd:cd13961   153 LIILLLALFAF------LITLG---REivkdiedvegDRAE-GARTLPIV--YGiKKAKKIAALLLLLAILLSPLPYLLG 220

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1490892732 236 LSGITFLIIAQALGLAFAVAALPFYRERTRLTARRLFLASIIYLPLLLI 284
Cdd:cd13961   221 GLGILYLILIIIADLLFLYSAIRLAKSPKDYSKLSKLLKLAMLLGLLAF 269
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
 14-287 1.48e-06

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 48.80  E-value: 1.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  14 YLEMSKARLSAMVVFSTIAGYLLSSRGAGHLDHLLWTALGTALAAFGASIFNQILETELDaKMERTqDRPLPSGRMPRGR 93
Cdd:PRK09573    6 YFELIRPKNCIGASIGAIIGYLIASNFKIDLKGIILAALVVFLVCAGGNVINDIYDIEID-KINKP-ERPIPSGRISLKE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  94 AQIYGWASSVAGVVlLATFVNLLTSALA-LAVILVYTLVYTPMKIRTSANTLVGAVVGAVppvigwtAYSGRIEIGALIL 172
Cdd:PRK09573   84 AKIFSITLFIVGLI-LSIFINIYAFLIAlLNSILLYLYAKDLKKTGLIGNLIVAYLTGLS-------FIFGGLAVFNVLR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 173 FGILFtwqvphFLALAWMYR-------EDY---ARGGFQMLPAVdaLGR----FTARTALVYALALQPLTlmvYAEGLSG 238
Cdd:PRK09573  156 IIILF------LCAFFSTWSreivkdiEDIegdLKENVITLPIK--YGIkkswYIAKILLILAIVLSPLP---YFLGIFG 224

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1490892732 239 ITFLIIAQALGLAFAVAALPFYRERTRLTARRLFLASIIYLPLLLISMV 287
Cdd:PRK09573  225 IYYLIVVIICDILFIIAMLILLKNPSIEGASKASKYLKIIMILGLIAFL 273
ubiA PRK12888
4-hydroxybenzoate octaprenyltransferase;
43-233 2.54e-06

4-hydroxybenzoate octaprenyltransferase;


Pssm-ID: 183814  Cd Length: 284  Bit Score: 48.18  E-value: 2.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  43 HLDHLLWTALGTALAAFGASIFNQILETELDAKMERTQDRPLPSGRMPRGRAQIygwASSVAGVVLLATFVNLLTSALAL 122
Cdd:PRK12888   37 HWADLLLVTVAMVGARTFAMAANRIIDREIDARNPRTAGRELVTGAVSVRTAWT---GALVALAVFLGAAALLNPLCLAL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 123 AVILVYTLVYTPMKIR-TSANTLVGAVVGAVPPVIGWTAYSGRIEIGALILFGILFTWQVPHFLALAWMYREDYARGGFQ 201
Cdd:PRK12888  114 APLAVAPLVVYPYAKRfTNFPHAILGLAQAVGPVGAWIAVTGTWSWPAVLLGLAVGLWIGGFDLIYACQDAEVDRRIGVR 193

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1490892732 202 MLPAvdalgRFTARTALVYALALQPLTLMVYA 233
Cdd:PRK12888  194 SVPA-----RFGVRAALWASRVAHVVTFALFV 220
ubiA PRK12884
prenyltransferase; Reviewed
 14-288 1.19e-04

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 43.02  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  14 YLEMSKARLSAMVVFSTIAGYLLSSRGAGhldhlLWTALGTALAAFGAS----IFNQILETELDAKmERTqDRPLPSGRM 89
Cdd:PRK12884    7 YLELLRPEHGLMAGIAVVLGAIIALGGLP-----LDEALLGFLTAFFASgsanALNDYFDYEVDRI-NRP-DRPIPSGRI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  90 PRGRAQIYGWASSVAGVVlLATFVNLLTSALALAVILVYTLVYTPMKIRTSANTLVGAVVGAVPPVIGWTAYSGRIEIGa 169
Cdd:PRK12884   80 SRREALLLAILLFILGLI-AAYLISPLAFLVVILVSVLGILYNWKLKEYGLIGNLYVAFLTGMTFIFGGIAVGELNEAV- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732 170 LILFGILFTWQVPHFLALAWMYREDYARGGFQMLPAVDALgRFTARTALVYALALQPLTLMVYAEGLSGITFLIIAQALG 249
Cdd:PRK12884  158 ILLAAMAFLMTLGREIMKDIEDVEGDRLRGARTLAILYGE-KIAGRIAAALFILAVLLSPLPYLFGIFNILYLAPVLVAD 236

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1490892732 250 LAFAVAALPFYRERTRLTARRlflASIIYLPLLLISMVG 288
Cdd:PRK12884  237 LIFLYSAYSLLRSQDRETIRK---VRKITLTAMLLALVA 272
ubiA PRK12874
4-hydroxybenzoate polyprenyltransferase;
64-177 7.77e-03

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 237242  Cd Length: 291  Bit Score: 37.29  E-value: 7.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1490892732  64 FNQILETELDAKMERTQDRPLPSGRMPRGRAQIYGWASSVaGVVLLATFVNLLTSALALAVILVYTLvYTPMKIRTSANT 143
Cdd:PRK12874   66 FNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLFIVLNAL-IFIGVSYFINPLAFKLSFPFLIVLGG-YSYFKRFSSLAH 143

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1490892732 144 LVGAVVGAVPPVIGWTAYSGRIEIGALIL-FGILF 177
Cdd:PRK12874  144 LVLGLSLGLAPIAGVVAVLGEIPLWSVFLaLGVMF 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH