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Conserved domains on  [gi|148872370|gb|ABR14860|]
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leucine-rich 15-repeat translocated effector protein (plasmid) [Yersinia pestis CA88-4125]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000960)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15370 super family cl33128
type III secretion system effector E3 ubiquitin transferase SlrP;
24-371 1.02e-45

type III secretion system effector E3 ubiquitin transferase SlrP;


The actual alignment was detected with superfamily member PRK15370:

Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 167.95  E-value: 1.02e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  24 TEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPE-LPPHLESLVASCNS 102
Cdd:PRK15370 131 SEQASSASGSKDAVNYELIWSEWVKEAPAKEAANREEAVQRMRDCLKNNKTELRLKILGLTTIPAcIPEQITTLILDNNE 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 103 LTELPE-LPQSLKSLLVDNNNLKALSD-LPPLLEYLGVSNNQLEKLPELQNSSfLKIIDVDNNSLKKLPD-LPPSLEFIA 179
Cdd:PRK15370 211 LKSLPEnLQGNIKTLYANSNQLTSIPAtLPDTIQEMELSINRITELPERLPSA-LQSLDLFHNKISCLPEnLPEELRYLS 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 180 AGNNQLEELPElqNLPF-LTAIYADNNSLKKLPD-LPLSLESIVAGNNILEELPElqnlpflttiyadnnllktlpDLPP 257
Cdd:PRK15370 290 VYDNSIRTLPA--HLPSgITHLNVQSNSLTALPEtLPPGLKTLEAGENALTSLPA---------------------SLPP 346

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 258 SLEALNVRDNYLTDLPElpqsltfldvsenifsglselppnlyylnassneirslcDLPPSLEELNVSNNKLIELPA-LP 336
Cdd:PRK15370 347 ELQVLDVSKNQITVLPE---------------------------------------TLPPTITTLDVSRNALTNLPEnLP 387

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 148872370 337 PRLERLIASFNHLAEVPE-LPQNLKQ------LHVEYNPLRE 371
Cdd:PRK15370 388 AALQIMQASRNNLVRLPEsLPHFRGEgpqptrIIVEYNPFSE 429
 
Name Accession Description Interval E-value
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
24-371 1.02e-45

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 167.95  E-value: 1.02e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  24 TEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPE-LPPHLESLVASCNS 102
Cdd:PRK15370 131 SEQASSASGSKDAVNYELIWSEWVKEAPAKEAANREEAVQRMRDCLKNNKTELRLKILGLTTIPAcIPEQITTLILDNNE 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 103 LTELPE-LPQSLKSLLVDNNNLKALSD-LPPLLEYLGVSNNQLEKLPELQNSSfLKIIDVDNNSLKKLPD-LPPSLEFIA 179
Cdd:PRK15370 211 LKSLPEnLQGNIKTLYANSNQLTSIPAtLPDTIQEMELSINRITELPERLPSA-LQSLDLFHNKISCLPEnLPEELRYLS 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 180 AGNNQLEELPElqNLPF-LTAIYADNNSLKKLPD-LPLSLESIVAGNNILEELPElqnlpflttiyadnnllktlpDLPP 257
Cdd:PRK15370 290 VYDNSIRTLPA--HLPSgITHLNVQSNSLTALPEtLPPGLKTLEAGENALTSLPA---------------------SLPP 346

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 258 SLEALNVRDNYLTDLPElpqsltfldvsenifsglselppnlyylnassneirslcDLPPSLEELNVSNNKLIELPA-LP 336
Cdd:PRK15370 347 ELQVLDVSKNQITVLPE---------------------------------------TLPPTITTLDVSRNALTNLPEnLP 387

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 148872370 337 PRLERLIASFNHLAEVPE-LPQNLKQ------LHVEYNPLRE 371
Cdd:PRK15370 388 AALQIMQASRNNLVRLPEsLPHFRGEgpqptrIIVEYNPFSE 429
TTSSLRR pfam12468
Type III secretion system leucine rich repeat protein; This domain family is found in bacteria, ...
 8-63 3.11e-15

Type III secretion system leucine rich repeat protein; This domain family is found in bacteria, and is approximately 50 amino acids in length. There are two completely conserved residues (Y and W) that may be functionally important. This family consists of leucine-rich repeat proteins involved in type III secretion.


Pssm-ID: 432576 [Multi-domain]  Cd Length: 54  Bit Score: 69.50  E-value: 3.11e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 148872370    8 VSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPgnGEQREMAVS 63
Cdd:pfam12468   1 INNNFSGSSVSFSNISSDRSVESEREKTPADYLRIWDEWEKNAPP--GEQRGEAVR 54
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-375 3.20e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.90  E-value: 3.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   1 MFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNN 80
Cdd:COG4886   21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  81 LGLSSLPELP--PHLESLVASCNSLTELPELPQSLKSLlvdnnnlkalsdlppllEYLGVSNNQLEKLPE-LQNSSFLKI 157
Cdd:COG4886  101 LDLSGNEELSnlTNLESLDLSGNQLTDLPEELANLTNL-----------------KELDLSNNQLTDLPEpLGNLTNLKS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 158 IDVDNNSLKKLPDLP---PSLEFIAAGNNQLEELP-ELQNLPFLTAIYADNNSLKKLPDlPLS----LESIVAGNNILEE 229
Cdd:COG4886  164 LDLSNNQLTDLPEELgnlTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPE-PLAnltnLETLDLSNNQLTD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 230 LPELQNLPFLTTIYADNNLLKTLPDLP--PSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSN 307
Cdd:COG4886  243 LPELGNLTNLEELDLSNNQLTDLPPLAnlTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148872370 308 EIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDI 375
Cdd:COG4886  323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 161-352 6.65e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 58.64  E-value: 6.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 161 DNNSLKKLPDLP--PSLEFIAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDlplslesivagnnileelpeLQNLPF 238
Cdd:cd21340   10 NDKNITKIDNLSlcKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIEN--------------------LENLVN 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 239 LTTIYADNNLLKTLPDL--PPSLEALNVRDNyltDLPElPQSLTFLDVSenifsgLSELPPNLYYLNASSNEIRSLCDLP 316
Cdd:cd21340   70 LKKLYLGGNRISVVEGLenLTNLEELHIENQ---RLPP-GEKLTFDPRS------LAALSNSLRVLNISGNNIDSLEPLA 139

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 148872370 317 P--SLEELNVSNNKLIELPAlpprLERLIASFNHLAEV 352
Cdd:cd21340  140 PlrNLEQLDASNNQISDLEE----LLDLLSSWPSLREL 173
 
Name Accession Description Interval E-value
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
24-371 1.02e-45

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 167.95  E-value: 1.02e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  24 TEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPE-LPPHLESLVASCNS 102
Cdd:PRK15370 131 SEQASSASGSKDAVNYELIWSEWVKEAPAKEAANREEAVQRMRDCLKNNKTELRLKILGLTTIPAcIPEQITTLILDNNE 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 103 LTELPE-LPQSLKSLLVDNNNLKALSD-LPPLLEYLGVSNNQLEKLPELQNSSfLKIIDVDNNSLKKLPD-LPPSLEFIA 179
Cdd:PRK15370 211 LKSLPEnLQGNIKTLYANSNQLTSIPAtLPDTIQEMELSINRITELPERLPSA-LQSLDLFHNKISCLPEnLPEELRYLS 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 180 AGNNQLEELPElqNLPF-LTAIYADNNSLKKLPD-LPLSLESIVAGNNILEELPElqnlpflttiyadnnllktlpDLPP 257
Cdd:PRK15370 290 VYDNSIRTLPA--HLPSgITHLNVQSNSLTALPEtLPPGLKTLEAGENALTSLPA---------------------SLPP 346

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 258 SLEALNVRDNYLTDLPElpqsltfldvsenifsglselppnlyylnassneirslcDLPPSLEELNVSNNKLIELPA-LP 336
Cdd:PRK15370 347 ELQVLDVSKNQITVLPE---------------------------------------TLPPTITTLDVSRNALTNLPEnLP 387

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 148872370 337 PRLERLIASFNHLAEVPE-LPQNLKQ------LHVEYNPLRE 371
Cdd:PRK15370 388 AALQIMQASRNNLVRLPEsLPHFRGEgpqptrIIVEYNPFSE 429
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
34-404 1.57e-35

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 138.76  E-value: 1.57e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  34 KSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPE-LPPHLESLVASCNSLTELPELPQS 112
Cdd:PRK15387 164 QTPAEYDAVWSAWRRAAPAEESRGRAAVVQKMRACLNNGNAVLNVGESGLTTLPDcLPAHITTLVIPDNNLTSLPALPPE 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 113 LKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELqnSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLEELPELQ 192
Cdd:PRK15387 244 LRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPAL--PSGLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPALP 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 193 NLpfltaiyadnnslkklpdlplslesivagnnileelpelqnlpfLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDL 272
Cdd:PRK15387 322 SE--------------------------------------------LCKLWAYNNQLTSLPTLPSGLQELSVSDNQLASL 357

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 273 PELPQSLTfldvsenifsglselppnlyylnassneirslcdlppsleELNVSNNKLIELPALPPRLERLIASFNHLAEV 352
Cdd:PRK15387 358 PTLPSELY----------------------------------------KLWAYNNRLTSLPALPSGLKELIVSGNRLTSL 397

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 148872370 353 PELPQNLKQLHVEYNPLREFPDIPESVEDLRMNSERVVD-PYEFAH---ETTDKLE 404
Cdd:PRK15387 398 PVLPSELKELMVSGNRLTSLPMLPSGLLSLSVYRNQLTRlPESLIHlssETTVNLE 453
TTSSLRR pfam12468
Type III secretion system leucine rich repeat protein; This domain family is found in bacteria, ...
 8-63 3.11e-15

Type III secretion system leucine rich repeat protein; This domain family is found in bacteria, and is approximately 50 amino acids in length. There are two completely conserved residues (Y and W) that may be functionally important. This family consists of leucine-rich repeat proteins involved in type III secretion.


Pssm-ID: 432576 [Multi-domain]  Cd Length: 54  Bit Score: 69.50  E-value: 3.11e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 148872370    8 VSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPgnGEQREMAVS 63
Cdd:pfam12468   1 INNNFSGSSVSFSNISSDRSVESEREKTPADYLRIWDEWEKNAPP--GEQRGEAVR 54
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-375 3.20e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.90  E-value: 3.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   1 MFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNN 80
Cdd:COG4886   21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  81 LGLSSLPELP--PHLESLVASCNSLTELPELPQSLKSLlvdnnnlkalsdlppllEYLGVSNNQLEKLPE-LQNSSFLKI 157
Cdd:COG4886  101 LDLSGNEELSnlTNLESLDLSGNQLTDLPEELANLTNL-----------------KELDLSNNQLTDLPEpLGNLTNLKS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 158 IDVDNNSLKKLPDLP---PSLEFIAAGNNQLEELP-ELQNLPFLTAIYADNNSLKKLPDlPLS----LESIVAGNNILEE 229
Cdd:COG4886  164 LDLSNNQLTDLPEELgnlTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPE-PLAnltnLETLDLSNNQLTD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 230 LPELQNLPFLTTIYADNNLLKTLPDLP--PSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSN 307
Cdd:COG4886  243 LPELGNLTNLEELDLSNNQLTDLPPLAnlTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148872370 308 EIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDI 375
Cdd:COG4886  323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
78-372 2.73e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.20  E-value: 2.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  78 LNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELQNSSFLKI 157
Cdd:COG4886    2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 158 IDVDNNSLKKLPDLPPSLEFIAAGNNQLEELPELQNLpfltaiYADNNSLKKLPDL---PLSLESIVAGNNILEELPE-L 233
Cdd:COG4886   82 LSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESL------DLSGNQLTDLPEElanLTNLKELDLSNNQLTDLPEpL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 234 QNLPFLTTIYADNNLLKTLPDLP---PSLEALNVRDNYLTDLPEL---PQSLTFLDVSENifsGLSELPPNLYYLnassn 307
Cdd:COG4886  156 GNLTNLKSLDLSNNQLTDLPEELgnlTNLKELDLSNNQITDLPEPlgnLTNLEELDLSGN---QLTDLPEPLANL----- 227

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 148872370 308 eirslcdlpPSLEELNVSNNKLIELPALP--PRLERLIASFNHLAEVPELPQ--NLKQLHVEYNPLREF 372
Cdd:COG4886  228 ---------TNLETLDLSNNQLTDLPELGnlTNLEELDLSNNQLTDLPPLANltNLKTLDLSNNQLTDL 287
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
75-308 1.44e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 62.64  E-value: 1.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  75 ELELNNLGLSSLPELP---PHLESLVASCNSLTELPEL---PQSLKSLLVDNNNLKALSD-LPPL--LEYLGVSNNQLEK 145
Cdd:COG4886  163 SLDLSNNQLTDLPEELgnlTNLKELDLSNNQITDLPEPlgnLTNLEELDLSGNQLTDLPEpLANLtnLETLDLSNNQLTD 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 146 LPELQNSSFLKIIDVDNNSLKKLPDLP--PSLEFIAAGNNQ-----LEELPELQNLPFLTAIYADNNSLKKLPDLPLSLE 218
Cdd:COG4886  243 LPELGNLTNLEELDLSNNQLTDLPPLAnlTNLKTLDLSNNQltdlkLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 219 SIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPN 298
Cdd:COG4886  323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLL 402

                        250
                 ....*....|
gi 148872370 299 LYYLNASSNE 308
Cdd:COG4886  403 LTLALLDAVN 412
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 161-352 6.65e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 58.64  E-value: 6.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 161 DNNSLKKLPDLP--PSLEFIAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDlplslesivagnnileelpeLQNLPF 238
Cdd:cd21340   10 NDKNITKIDNLSlcKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIEN--------------------LENLVN 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 239 LTTIYADNNLLKTLPDL--PPSLEALNVRDNyltDLPElPQSLTFLDVSenifsgLSELPPNLYYLNASSNEIRSLCDLP 316
Cdd:cd21340   70 LKKLYLGGNRISVVEGLenLTNLEELHIENQ---RLPP-GEKLTFDPRS------LAALSNSLRVLNISGNNIDSLEPLA 139

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 148872370 317 P--SLEELNVSNNKLIELPAlpprLERLIASFNHLAEV 352
Cdd:cd21340  140 PlrNLEQLDASNNQISDLEE----LLDLLSSWPSLREL 173
PRK14707 PRK14707
hypothetical protein; Provisional
 32-404 1.63e-09

hypothetical protein; Provisional


Pssm-ID: 173170 [Multi-domain]  Cd Length: 2710  Bit Score: 60.19  E-value: 1.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   32 NVKSKTEYYNAWSEWERNAPPGNGEQREMAV----SRLRDCLDRQAHELELNnlGLSSLPELPPHLESLVASCNSLTELP 107
Cdd:PRK14707  161 NAQNISLALNAFSKWSDNPDCQAVAPRFAALvasdDRLRSAMDAQGVATVLN--ALCKWPDTPDCGNAVSALAERLADES 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  108 ELPQSLKSLLVDN--NNLKALSDLPPLLEYLGVSNNQLEKLPELQNSsfLKIIDVDN--NSLKKLPDLPPSLEFIAAGNN 183
Cdd:PRK14707  239 RLRNELKPQELGNalNALSKWADTPVCAAAASALAERLVDDPGLRKA--LDPINVTQalNALSKWADLPVCAEAAIALAE 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  184 QLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALN 263
Cdd:PRK14707  317 RLADDPELCKALNARGLSTALNALSKWPDNPVCAAAVSALAERLVADPELRKDLEPQGVSSVLNALSKWPDTPVCAAAAS 396

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  264 VRDNYLTDLPELPQSLTFLDVSE--NIFSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSN--NKLIELPALPPRL 339
Cdd:PRK14707  397 ALAEHVVDDLELRKGLDPQGVSNalNALAKWPDLPICGQAVSALAGRLAHDTELCKALDPINVTQalDALSKWPDTPICG 476

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148872370  340 ERLIASFNHLAEVPELPQNLK--QLHVEYNPLREFPDIPESVEDLRMNSERVVDPYEF-----AHETTDKLE 404
Cdd:PRK14707  477 QTASALAARLAHERRLRKALKpqEVVIALHSLSKWPDTPICAEAASALAERVVDELQLrkafdAHQVVNTLK 548
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 119-267 4.30e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 4.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 119 DNNNLKALSDLPPL--LEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLP--PSLEFIAAGNNQLEELPELQNL 194
Cdd:cd21340   10 NDKNITKIDNLSLCknLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLEnlVNLKKLYLGGNRISVVEGLENL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 195 PFLTAIYADNNSLK---KLPDLPLSLESI--------VAGNNIlEELPELQNLPFLTTIYADNNLLKTLPDLP------P 257
Cdd:cd21340   90 TNLEELHIENQRLPpgeKLTFDPRSLAALsnslrvlnISGNNI-DSLEPLAPLRNLEQLDASNNQISDLEELLdllsswP 168

                        170
                 ....*....|
gi 148872370 258 SLEALNVRDN 267
Cdd:cd21340  169 SLRELDLTGN 178
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 76-329 2.02e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 46.19  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  76 LELNNLGLSSLPELPPHLESLVASCNSLTELpELPQSLKSLlvdnnnlkalsDLPPLLEYLGVSNNQLEKLPE------- 148
Cdd:cd00116    8 ELLKTERATELLPKLLCLQVLRLEGNTLGEE-AAKALASAL-----------RPQPSLKELCLSLNETGRIPRglqsllq 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 149 -LQNSSFLKIIDVDNNSLkkLPDLPPSLEFIAAgNNQLEELPELQN------LPFLTaiyadnnslKKLPDLPLSLESIV 221
Cdd:cd00116   76 gLTKGCGLQELDLSDNAL--GPDGCGVLESLLR-SSSLQELKLNNNglgdrgLRLLA---------KGLKDLPPALEKLV 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 222 AGNNILE---------ELPELQNLPFLTtiYADNNLL-----KTLPDLP--PSLEALNVRDNYLTD--------LPELPQ 277
Cdd:cd00116  144 LGRNRLEgascealakALRANRDLKELN--LANNGIGdagirALAEGLKanCNLEVLDLNNNGLTDegasalaeTLASLK 221

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 148872370 278 SLTFLDVSEN---------IFSGLSELPPNLYYLNASSNEI-----RSLC---DLPPSLEELNVSNNKL 329
Cdd:cd00116  222 SLEVLNLGDNnltdagaaaLASALLSPNISLLTLSLSCNDItddgaKDLAevlAEKESLLELDLRGNKF 290
PRK14707 PRK14707
hypothetical protein; Provisional
 41-391 2.14e-05

hypothetical protein; Provisional


Pssm-ID: 173170 [Multi-domain]  Cd Length: 2710  Bit Score: 47.09  E-value: 2.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   41 NAWSEWERN----APPGNGEQREMAVSRLRDCLDRQAHELELNnlGLSSLPELPPHLESLVASCNSLTELPELPQSLKSL 116
Cdd:PRK14707  674 NALSKWPDTpvcaAAAGGMAERLAADPGLRKELNPVDVANALN--ALSKWPRTPVCAAVASALAARVVAEPRLRKAFDAQ 751

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  117 LVdNNNLKALSDLPPLLEYLGVSNNQLEK-LPELQNSSFLKIIDVDN--NSLKKLPDLPPSLEFIAAGNNQLEELPELQN 193
Cdd:PRK14707  752 QV-ATALNALSKWPDNQACAAAANTLAERqLREPDVRDVLKPREMTNalNALSKWPDTPACAAAASALAARVADDPRLRE 830

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  194 LPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLP 273
Cdd:PRK14707  831 AFDVQHVATVLNAMSKWPDNAVCAAAAGAMAERLADEPELRHTLTAHGVVIVLNALSKWPNVPVCAAAASALAERLADEP 910

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  274 ELPQSLTFLDVSENIfSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSNnklielpalpprlerliasfnhlaevp 353
Cdd:PRK14707  911 ELRKALSAHRVATAL-NALSKWPDIPVCATAASALAERLSDDPDLREALDASN--------------------------- 962

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 148872370  354 eLPQNLkqlhveyNPLREFPDIPESVEDLRMNSERVVD 391
Cdd:PRK14707  963 -LPQVL-------NALSKWPDVPAGGEVVDALAERLVD 992
PRK14707 PRK14707
hypothetical protein; Provisional
 29-334 2.64e-05

hypothetical protein; Provisional


Pssm-ID: 173170 [Multi-domain]  Cd Length: 2710  Bit Score: 46.71  E-value: 2.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   29 EAENVKSKTEYYNAWSEWERNA----PPGNGEQREMAVSRLRDCLDRQAHELELNnlGLSSLPELPPHLESLVASCNSLT 104
Cdd:PRK14707  830 EAFDVQHVATVLNAMSKWPDNAvcaaAAGAMAERLADEPELRHTLTAHGVVIVLN--ALSKWPNVPVCAAAASALAERLA 907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  105 ELPELPQSLKSLLVDN--NNLKALSDLPPLLEYLGVSNNQLEKLPELQNSsflkiIDVDN-----NSLKKLPDLPPSLEF 177
Cdd:PRK14707  908 DEPELRKALSAHRVATalNALSKWPDIPVCATAASALAERLSDDPDLREA-----LDASNlpqvlNALSKWPDVPAGGEV 982

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  178 IAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPEL---QNLPFLTTIYadnNLLKTLPD 254
Cdd:PRK14707  983 VDALAERLVDEPALRNALDPIGMANALNALSKWLQMPVCAATVEALAARLSNDPGLckaLSSQGLTTVL---NALCKWPE 1059

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  255 LPPSLEALNVRDNYLTDLPELPQSLTFLDVSeNIFSGLSELPPNLYYLNASSNEIRSLCD---LPPSLEELNVSN--NKL 329
Cdd:PRK14707 1060 MPVCLAAASALAERLSDDLVLRNALDSQGFG-NALNALSKWPDSPVCAAAASALAKRLTDdagLRHVFDPINVSQalNAL 1138


                  ....*
gi 148872370  330 IELPA 334
Cdd:PRK14707 1139 SKWPG 1143
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 93-359 9.65e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.84  E-value: 9.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  93 LESLVASCNSLT-ELPELP---QSLKSLLVDNNNL-----KALSDLPPLLEYLGVSNNQLEKLP-ELQNSSFLKIIDVDN 162
Cdd:PLN00113 286 LISLDLSDNSLSgEIPELViqlQNLEILHLFSNNFtgkipVALTSLPRLQVLQLWSNKFSGEIPkNLGKHNNLTVLDLST 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 163 NSLK-KLPDlppslEFIAAGNnqleelpelqnlpfLTAIYADNNSLKKL--PDLPL--SLESIVAGNNILE-ELP-ELQN 235
Cdd:PLN00113 366 NNLTgEIPE-----GLCSSGN--------------LFKLILFSNSLEGEipKSLGAcrSLRRVRLQDNSFSgELPsEFTK 426

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 236 LPFLTTI-YADNNLLKTLPDLP---PSLEALNV-RDNYLTDLPELPQS--LTFLDVSENIFSGLSELP----PNLYYLNA 304
Cdd:PLN00113 427 LPLVYFLdISNNNLQGRINSRKwdmPSLQMLSLaRNKFFGGLPDSFGSkrLENLDLSRNQFSGAVPRKlgslSELMQLKL 506

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 148872370 305 SSNEIRSlcDLPPSLEE------LNVSNNKLI-ELPAL---PPRLERLIASFNHLAEvpELPQNL 359
Cdd:PLN00113 507 SENKLSG--EIPDELSSckklvsLDLSHNQLSgQIPASfseMPVLSQLDLSQNQLSG--EIPKNL 567
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
182-374 2.82e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.00  E-value: 2.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 182 NNQLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEA 261
Cdd:COG4886    2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 262 LNVRDNYLTDLPELPQsLTFLDVSENifSGLSELpPNLYYLNASSNEIRSLCDL---PPSLEELNVSNNKLIELPA-LP- 336
Cdd:COG4886   82 LSLLLLGLTDLGDLTN-LTELDLSGN--EELSNL-TNLESLDLSGNQLTDLPEElanLTNLKELDLSNNQLTDLPEpLGn 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 148872370 337 -PRLERLIASFNHLAEVPELP---QNLKQLHVEYNPLREFPD 374
Cdd:COG4886  158 lTNLKSLDLSNNQLTDLPEELgnlTNLKELDLSNNQITDLPE 199
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 206-385 3.60e-04

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 42.94  E-value: 3.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  206 SLKKLPDLPL--SLESIVAGN-NILEELPE----LQNLPFLTTIYADNnlLKTLP---DLPpSLEALNVRD-NYLTDLPE 274
Cdd:PLN03210  646 NLKEIPDLSMatNLETLKLSDcSSLVELPSsiqyLNKLEDLDMSRCEN--LEILPtgiNLK-SLYRLNLSGcSRLKSFPD 722

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  275 LPQSLTFLDVSEnifSGLSELPP-----NLYYLNASSNEIRSLCD-----------LPPSLEELNVSNN-KLIELPALPP 337
Cdd:PLN03210  723 ISTNISWLDLDE---TAIEEFPSnlrleNLDELILCEMKSEKLWErvqpltplmtmLSPSLTRLFLSDIpSLVELPSSIQ 799

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 148872370  338 RLERLiasfNHLA-----EVPELPQNLKQLHVEY------NPLREFPDIPESVEDLRMN 385
Cdd:PLN03210  800 NLHKL----EHLEienciNLETLPTGINLESLESldlsgcSRLRTFPDISTNISDLNLS 854
PRK15386 PRK15386
type III secretion effector GogB;
29-238 4.62e-04

type III secretion effector GogB;


Pssm-ID: 237954 [Multi-domain]  Cd Length: 426  Bit Score: 42.16  E-value: 4.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  29 EAENVKSKTEYYNAWSEWERNAPpgnGEQREMAVSRLRDclDRQAHELELNNLGLSSLPELPPHLESL-VASCNSLTELP 107
Cdd:PRK15386  15 EAMLSTSQLEPDGTFCSNSTETS---AEIRSEITPQIEE--ARASGRLYIKDCDIESLPVLPNELTEItIENCNNLTTLP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370 108 E-LPQSLKSLLVdnNNLKALSDLPPLLEYLGvsnnqleklpelQNSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLE 186
Cdd:PRK15386  90 GsIPEGLEKLTV--CHCPEISGLPESVRSLE------------IKGSATDSIKNVPNGLTSLSINSYNPENQARIDNLIS 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 148872370 187 ELPELQNLPFLTAIyadnnslkKLPD-LPLSLESIvagnNILEELPELQNLPF 238
Cdd:PRK15386 156 PSLKTLSLTGCSNI--------ILPEkLPESLQSI----TLHIEQKTTWNISF 196
PRK14707 PRK14707
hypothetical protein; Provisional
 65-296 9.81e-04

hypothetical protein; Provisional


Pssm-ID: 173170 [Multi-domain]  Cd Length: 2710  Bit Score: 41.70  E-value: 9.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   65 LRDCLDRQAHELELNnlGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVdNNNLKALS---DLPPLLEYLGVSNN 141
Cdd:PRK14707  408 LRKGLDPQGVSNALN--ALAKWPDLPICGQAVSALAGRLAHDTELCKALDPINV-TQALDALSkwpDTPICGQTASALAA 484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  142 QLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLeeLPELQNLPFLTAiYADNNSLKKLPDLPLSLESIV 221
Cdd:PRK14707  485 RLAHERRLRKALKPQEVVIALHSLSKWPDTPICAEAASALAERV--VDELQLRKAFDA-HQVVNTLKALSKWPDKQLCAV 561

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148872370  222 AGNNILEELPELQNLP---FLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSeNIFSGLSELP 296
Cdd:PRK14707  562 AASGLAERLADEPQLPkdlHRQGVVIVLNALSKWPDTAVCAEAVNALAERLVDEPDLRKELDPVDVT-NVLNALSKWP 638
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 75-347 3.37e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 39.86  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   75 ELELNNLglSSLPELPP------HLESLVAS-CNSLTELPeLPQSLKSLLVDN----NNLKALSDLPPLLEYLGVSNNQL 143
Cdd:PLN03210  661 TLKLSDC--SSLVELPSsiqylnKLEDLDMSrCENLEILP-TGINLKSLYRLNlsgcSRLKSFPDISTNISWLDLDETAI 737

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  144 EKLPE---LQNSSFLKIIDVDNNSLKK--------LPDLPPSLEFIAAGNNQ-LEELP-ELQNLpfltaiyadnNSLKKL 210
Cdd:PLN03210  738 EEFPSnlrLENLDELILCEMKSEKLWErvqpltplMTMLSPSLTRLFLSDIPsLVELPsSIQNL----------HKLEHL 807

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  211 pdlplsleSIVAGNNiLEELPELQNLPFLTTI-YADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLD-VSENI 288
Cdd:PLN03210  808 --------EIENCIN-LETLPTGINLESLESLdLSGCSRLRTFPDISTNISDLNLSRTGIEEVPWWIEKFSNLSfLDMNG 878

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148872370  289 FSGLSELPPNLYYLNASSNEIRSLC--------DLPPSlEELNVSNNKLIELPALPPrlERLIASFN 347
Cdd:PLN03210  879 CNNLQRVSLNISKLKHLETVDFSDCgalteaswNGSPS-EVAMATDNIHSKLPSTVC--INFINCFN 942
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 49-296 5.27e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 39.09  E-value: 5.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370   49 NAPPGNGEQREMAVSRLRDCLDrQAHEL----ELNNLGLSSLPELP-----PHLESL-VASCNSLTELPELPQSLksllv 118
Cdd:PLN03210  607 NFRPENLVKLQMQGSKLEKLWD-GVHSLtglrNIDLRGSKNLKEIPdlsmaTNLETLkLSDCSSLVELPSSIQYL----- 680

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  119 dnNNLKALSdlpplLEYLgvsnNQLEKLPELQNSSFLKIIDVDNNS-LKKLPDLPPSLEFIAAGNNQLEELP---ELQNL 194
Cdd:PLN03210  681 --NKLEDLD-----MSRC----ENLEILPTGINLKSLYRLNLSGCSrLKSFPDISTNISWLDLDETAIEEFPsnlRLENL 749

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148872370  195 PFLTAIYADNNSL--KKLPDLPL------SLESIVAGNN-ILEELP-ELQNLPFLTTIYADNNL-LKTLPdlppslEALN 263
Cdd:PLN03210  750 DELILCEMKSEKLweRVQPLTPLmtmlspSLTRLFLSDIpSLVELPsSIQNLHKLEHLEIENCInLETLP------TGIN 823

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 148872370  264 VRDNYLTDLPELPQSLTFLDVSENIFS------GLSELP 296
Cdd:PLN03210  824 LESLESLDLSGCSRLRTFPDISTNISDlnlsrtGIEEVP 862
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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