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Conserved domains on  [gi|148762616|dbj|BAF64060|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Etrumeus micropus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-174 9.90e-53

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 165.70  E-value: 9.90e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPE 82
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  83 TLADDTAFEFVVFFVGLAAVGVMWFWGSWYEFGVGVLTSFKEFFVSRGDADGTGMLYFVGGFALGVSVVGLILALVVVLE 162
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|..
gi 148762616 163 LSRGSKRGCLRA 174
Cdd:MTH00138 161 LTRGLSRGALRA 172
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-174 9.90e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 165.70  E-value: 9.90e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPE 82
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  83 TLADDTAFEFVVFFVGLAAVGVMWFWGSWYEFGVGVLTSFKEFFVSRGDADGTGMLYFVGGFALGVSVVGLILALVVVLE 162
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|..
gi 148762616 163 LSRGSKRGCLRA 174
Cdd:MTH00138 161 LTRGLSRGALRA 172
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
19-118 1.12e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 45.57  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   19 IGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPETLADDTAFEFVVFFVG 98
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|
gi 148762616   99 LAAVGVMWFWGSWYEFGVGV 118
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAA 100
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-174 9.90e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 165.70  E-value: 9.90e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPE 82
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  83 TLADDTAFEFVVFFVGLAAVGVMWFWGSWYEFGVGVLTSFKEFFVSRGDADGTGMLYFVGGFALGVSVVGLILALVVVLE 162
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|..
gi 148762616 163 LSRGSKRGCLRA 174
Cdd:MTH00138 161 LTRGLSRGALRA 172
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 3-174 5.05e-33

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 115.33  E-value: 5.05e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPE 82
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  83 TLADDTAFEFVVFFVGLAAVGVMwFWGSWYEFGVGVLTSFKEFFVSRGDADGTGMLYFVGGFALGVSVVGLILALVVVLE 162
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYI-LFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|..
gi 148762616 163 LSRGSKRGCLRA 174
Cdd:MTH00065 160 VTRGLSRGSLRA 171
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 3-174 7.96e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 107.14  E-value: 7.96e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPE 82
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  83 TLADDTAFEFVVFFVGLAAVGVMWFWGSWYEFGVGVLT-SFKEFFVSRGDADGTGMLYFVGGFALGVSVVGLILALVVVL 161
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTvDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|...
gi 148762616 162 ELSRGSKRGCLRA 174
Cdd:MTH00115 161 ELVRGLSRGALRA 173
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 3-166 2.34e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 87.94  E-value: 2.34e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWL-VVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDP 81
Cdd:MTH00109   1 MMMYIVFILsVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  82 ETLADDTAFeFVVFFVGLAAVGVMWFWGSWYEfGVGVLTSFK-----------EFFVSRGDADGTGMLYFVGGFALGVSV 150
Cdd:MTH00109  81 ETWVSNKVV-LGALLLGLLMELLLVLYVLKDD-EVEVVFNFNglgdwviydtgGSGFFSEDAMGVAALYSYGTWLVVVTG 158

                        170
                 ....*....|....*.
gi 148762616 151 VGLILALVVVLELSRG 166
Cdd:MTH00109 159 WSLFIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 3-174 2.34e-16

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 72.33  E-value: 2.34e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPE 82
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  83 TLADDTAFEFVVFFVGLAAVGVMWFWGSWYEFGVGVLTSFKEFFVSrgdadGTGMLYFVGGFALGVSVVGLILALVVVLE 162
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDLS-----GVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|..
gi 148762616 163 LSRGSKRGCLRA 174
Cdd:MTH00214 156 LVRGLSRGALRV 167
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 5-174 3.81e-16

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 71.48  E-value: 3.81e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   5 LMIITWLVVLVLSIIGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPETL 84
Cdd:MTH00045   1 MVFYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616  85 ADDTAFEFVVFFVGLAAVGVMWFWGSWYEFGVgvltsfkefFVSRGDADGTGMLYFVGGFALGVSVVGLILALVVVLELS 164
Cdd:MTH00045  81 NLGEVLVLSLLLSLWVFISFDNFLELSNNNWS---------LVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVIS 151

                        170
                 ....*....|
gi 148762616 165 RGSKRGCLRA 174
Cdd:MTH00045 152 FGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
19-118 1.12e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 45.57  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148762616   19 IGVSSNPAPFYGALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALAADSDPETLADDTAFEFVVFFVG 98
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|
gi 148762616   99 LAAVGVMWFWGSWYEFGVGV 118
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAA 100
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 3-76 7.92e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 37.94  E-value: 7.92e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148762616   3 MELMIITWLVVLVLSIIGVSSNPAPFygALALVIAAGSGGVLLAVFGAPFLSLVFFLIYLGGMLVVFGYATALA 76
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSKQPLSL--GLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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