NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|148277058|ref|NP_001078949|]
View 

protein FAM162B [Homo sapiens]

Protein Classification

FAM162A family protein( domain architecture ID 10533950)

FAM162A (family with sequence similarity 162 member A) family protein; FAM162A also known as human growth and transformation-dependent protein (HGTD-P), is a hypoxia-inducible factor-1a (HIF-1a)-responsive protein which promotes intrinsic (mitochondrial mediated) apoptosis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF1075 pfam06388
Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of ...
 18-139 3.23e-61

Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of unknown function.


:

Pssm-ID: 461893  Cd Length: 124  Bit Score: 184.85  E-value: 3.23e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148277058   18 RCGPGAPLEATRRPAPALPPRGL----PCYSSGGAPSNSGPqgHGEIHRVPTqRRPSQFDKKILLWTGRFKSMEEIPPRI 93
Cdd:pfam06388   2 LCERGASSTLRLTRNTDLKRIRGlctkPQESSGAPPSSTVA--VRPVHRVPG-HKPTDFDKKILLWSGRFKKEEDIPETV 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 148277058   94 PPEMIDTARNKARVKACYIMIGLTIIACFAVIVSAKRAVERHESLT 139
Cdd:pfam06388  79 SFEMIDAAKNKARVKACYIMIALTIVGCIAMVISGKRAVKRHESLT 124
 
Name Accession Description Interval E-value
DUF1075 pfam06388
Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of ...
 18-139 3.23e-61

Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of unknown function.


Pssm-ID: 461893  Cd Length: 124  Bit Score: 184.85  E-value: 3.23e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148277058   18 RCGPGAPLEATRRPAPALPPRGL----PCYSSGGAPSNSGPqgHGEIHRVPTqRRPSQFDKKILLWTGRFKSMEEIPPRI 93
Cdd:pfam06388   2 LCERGASSTLRLTRNTDLKRIRGlctkPQESSGAPPSSTVA--VRPVHRVPG-HKPTDFDKKILLWSGRFKKEEDIPETV 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 148277058   94 PPEMIDTARNKARVKACYIMIGLTIIACFAVIVSAKRAVERHESLT 139
Cdd:pfam06388  79 SFEMIDAAKNKARVKACYIMIALTIVGCIAMVISGKRAVKRHESLT 124
 
Name Accession Description Interval E-value
DUF1075 pfam06388
Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of ...
 18-139 3.23e-61

Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of unknown function.


Pssm-ID: 461893  Cd Length: 124  Bit Score: 184.85  E-value: 3.23e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148277058   18 RCGPGAPLEATRRPAPALPPRGL----PCYSSGGAPSNSGPqgHGEIHRVPTqRRPSQFDKKILLWTGRFKSMEEIPPRI 93
Cdd:pfam06388   2 LCERGASSTLRLTRNTDLKRIRGlctkPQESSGAPPSSTVA--VRPVHRVPG-HKPTDFDKKILLWSGRFKKEEDIPETV 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 148277058   94 PPEMIDTARNKARVKACYIMIGLTIIACFAVIVSAKRAVERHESLT 139
Cdd:pfam06388  79 SFEMIDAAKNKARVKACYIMIALTIVGCIAMVISGKRAVKRHESLT 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH