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Conserved domains on  [gi|148235823|ref|NP_001091080|]
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kinocilin isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Kinocilin super family cl20908
Kinocilin protein; This family of kinocilin proteins is found in vertebrate. In mouse it has ...
 1-100 2.20e-51

Kinocilin protein; This family of kinocilin proteins is found in vertebrate. In mouse it has been shown that this protein is expressed primarily in the kinocilium of sensory cells in the inner ear.


The actual alignment was detected with superfamily member pfam15033:

Pssm-ID: 464458  Cd Length: 123  Bit Score: 157.33  E-value: 2.20e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235823    1 MDIPISSRDFRGLQLACVALGLVAGSIIIGISVSKAAAAMGGVFIGAAVLG-----------------------SLRIHP 57
Cdd:pfam15033   1 MDIPISSRDLRCLQLACVALGLVAGSIIIGVSVSKAAAAVGGIFIGAAGLGllilaypflkarfnldhilpaigNLRIHP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 148235823   58 HPGADHGEGRSSTNGNKEGARSSLSTVSRTLEKLKPGTRGAEE 100
Cdd:pfam15033  81 HPGPDHGEGRSSGNGNKEGARSSLSTVTRTLEKLKPGARGTEE 123
 
Name Accession Description Interval E-value
Kinocilin pfam15033
Kinocilin protein; This family of kinocilin proteins is found in vertebrate. In mouse it has ...
 1-100 2.20e-51

Kinocilin protein; This family of kinocilin proteins is found in vertebrate. In mouse it has been shown that this protein is expressed primarily in the kinocilium of sensory cells in the inner ear.


Pssm-ID: 464458  Cd Length: 123  Bit Score: 157.33  E-value: 2.20e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235823    1 MDIPISSRDFRGLQLACVALGLVAGSIIIGISVSKAAAAMGGVFIGAAVLG-----------------------SLRIHP 57
Cdd:pfam15033   1 MDIPISSRDLRCLQLACVALGLVAGSIIIGVSVSKAAAAVGGIFIGAAGLGllilaypflkarfnldhilpaigNLRIHP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 148235823   58 HPGADHGEGRSSTNGNKEGARSSLSTVSRTLEKLKPGTRGAEE 100
Cdd:pfam15033  81 HPGPDHGEGRSSGNGNKEGARSSLSTVTRTLEKLKPGARGTEE 123
 
Name Accession Description Interval E-value
Kinocilin pfam15033
Kinocilin protein; This family of kinocilin proteins is found in vertebrate. In mouse it has ...
 1-100 2.20e-51

Kinocilin protein; This family of kinocilin proteins is found in vertebrate. In mouse it has been shown that this protein is expressed primarily in the kinocilium of sensory cells in the inner ear.


Pssm-ID: 464458  Cd Length: 123  Bit Score: 157.33  E-value: 2.20e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235823    1 MDIPISSRDFRGLQLACVALGLVAGSIIIGISVSKAAAAMGGVFIGAAVLG-----------------------SLRIHP 57
Cdd:pfam15033   1 MDIPISSRDLRCLQLACVALGLVAGSIIIGVSVSKAAAAVGGIFIGAAGLGllilaypflkarfnldhilpaigNLRIHP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 148235823   58 HPGADHGEGRSSTNGNKEGARSSLSTVSRTLEKLKPGTRGAEE 100
Cdd:pfam15033  81 HPGPDHGEGRSSGNGNKEGARSSLSTVTRTLEKLKPGARGTEE 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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