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Conserved domains on  [gi|146330985|sp|Q32ZZ5|]
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RecName: Full=NADH-ubiquinone oxidoreductase chain 2; AltName: Full=NADH dehydrogenase subunit 2

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 5.82e-168

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 471.64  E-value: 5.82e-168
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLMLLE 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 5.82e-168

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 471.64  E-value: 5.82e-168
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLMLLE 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-296 6.96e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 101.73  E-value: 6.96e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   8 MIMATIILGTLIVMTSSHWLMVWIGFEMNMLA--ILpVLMKKYNPRSMEAATKYFLTQATASMLLMLAI--------TIN 77
Cdd:COG1007  106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSlyVL-VAFRRDDRRSSEAALKYFLLGALSSGFLLYGIsllygatgSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  78 LIYSGQWSTANPLNPT---TSIIMTLA-LAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQI----SPAI 149
Cdd:COG1007  185 LAGIAAALAAGGANSPlllLGLVLVLAgLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveaFPGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 150 NMDLLLSMSLMSVA---IGGWGGLNQTQLRKIMAYSSIAHMGWM------------TAVMTYnptMALLNLIIYILLTTT 214
Cdd:COG1007  265 AADWQLLLAVLAVLsmtVGNLAALAQTNVKRMLAYSSIAHAGYLllglaagtplgvSAALFY---LLAYLFMNLGAFAVI 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 215 TFMTFMLNSTTTTLSLSHTWNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYM 294
Cdd:COG1007  342 LLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYL 421


                 ..
gi 146330985 295 RL 296
Cdd:COG1007  422 RV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-276 2.05e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 98.15  E-value: 2.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   23 SSHWLMVWIGFEMNMLAILP-VLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSGQWS--------TANPLNPT 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSfdelskalTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   94 TSII---MTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILL-TWQKLAP-----MSILYQISPAINMDLLLSMSLMSVAI 164
Cdd:pfam00361  81 LLLLfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  165 GGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILL---------TTTTFMTFMLNSTTTTLSLSHTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLThglfsaglfLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 146330985  236 KTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSI 276
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWI 281
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 9-296 6.67e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 93.09  E-value: 6.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985    9 IMATIILGTLIVMTSSHWLMVWIGFEMNMLAILpVLM--KKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSG---- 82
Cdd:TIGR01770 107 LLLFALLGIFLLVSSNDLLSIYLGLELQSLCFY-VLAglKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGslnf 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   83 -----QWSTANPLNP---TTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAI----- 149
Cdd:TIGR01770 186 edlllFLSNGMLNISlllLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  150 --NMDLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGW-MTAVMTynPTMALLNLIIYILLTTTTFMTFMLNSTTT 226
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLA--GTLEGIKAVLFYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  227 TLSLSHTWNKT-----------PLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMR 295
Cdd:TIGR01770 344 LRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  .
gi 146330985  296 L 296
Cdd:TIGR01770 424 V 424
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 5.82e-168

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 471.64  E-value: 5.82e-168
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLMLLE 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 1.27e-119

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 348.72  E-value: 1.27e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAiNMDLLLSMSLM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*.
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLMLL 346
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-344 6.14e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 342.19  E-value: 6.14e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNsM 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK-P 319

                        330       340
                 ....*....|....*....|....
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLM 344
Cdd:MTH00112 320 KKNTLTATLTTLSTLLLPLSPMIL 343
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 3.10e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 324.95  E-value: 3.10e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNsM 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-N 319

                        330       340
                 ....*....|....*....|....*.
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLMLL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 1.73e-88

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 269.49  E-value: 1.73e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPsvnnmKMKWQFNSM 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFP-----QHSISLFSW 315

                        330       340
                 ....*....|....*....|
gi 146330985 321 KQTTHLPPLIVLSTLILPMS 340
Cdd:MTH00041 316 RNSGNITVYGVILSILSSIS 335
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 7.07e-83

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 255.28  E-value: 7.07e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLM 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*.
gi 146330985 321 KQTThLPPLIVLSTLILPMSPMLMLL 346
Cdd:MTH00200 321 SNLL-VGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-346 2.98e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 175.78  E-value: 2.98e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   1 MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIY 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  81 SgqwstaNPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQIspaINMDLLLSMSLM 160
Cdd:MTH00160  82 L------MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 161 SVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYStslTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYS---SLMLNYNKNKWNLKKKKN 309

                        330       340
                 ....*....|....*....|....*.
gi 146330985 321 KQTTHLPPLIVLSTLILPMSPMLMLL 346
Cdd:MTH00160 310 KFSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 7-320 4.43e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 167.37  E-value: 4.43e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   7 SMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSGQWSt 86
Cdd:MTH00144   7 LLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  87 anplnptTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINM-DLLLSMSLMSVAIG 165
Cdd:MTH00144  86 -------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 166 GWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPtMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLLTTTIL 245
Cdd:MTH00144 159 SIGGLNQTQVRALLAYSSISHTGWMLVAILHGS-WLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSII 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146330985 246 ILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSM 320
Cdd:MTH00144 238 SLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI 312
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-299 5.94e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 159.17  E-value: 5.94e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   6 LSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITInliysgQWS 85
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  86 TANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLMSVAIG 165
Cdd:MTH00011  82 FPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 166 GWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLLTTTIL 245
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 146330985 246 ILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYS 299
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-336 4.36e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 135.57  E-value: 4.36e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   7 SMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLiysgqwsT 86
Cdd:MTH00197   1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF-------S 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  87 ANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPaiNMDLLLSMSLMSVAIGG 166
Cdd:MTH00197  74 NLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 167 WGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLLTTTILI 246
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 247 LMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSMKQ--TT 324
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFilLM 311

                        330
                 ....*....|..
gi 146330985 325 HLPPLIVLSTLI 336
Cdd:MTH00197 312 MMLPLLMIFTMI 323
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-296 1.21e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 108.19  E-value: 1.21e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  13 IILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNP-RSMEAATKYFLTQATASMLLMLAIT-------------INL 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  79 IYSGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMdlLLSMS 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNI--LLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 159 LMSVAIGGWGGLNQTQLRKIMAYSSIAHMG---WMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSH--- 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFESIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEfsg 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146330985 233 TWNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-296 6.96e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 101.73  E-value: 6.96e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   8 MIMATIILGTLIVMTSSHWLMVWIGFEMNMLA--ILpVLMKKYNPRSMEAATKYFLTQATASMLLMLAI--------TIN 77
Cdd:COG1007  106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSlyVL-VAFRRDDRRSSEAALKYFLLGALSSGFLLYGIsllygatgSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  78 LIYSGQWSTANPLNPT---TSIIMTLA-LAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQI----SPAI 149
Cdd:COG1007  185 LAGIAAALAAGGANSPlllLGLVLVLAgLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveaFPGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 150 NMDLLLSMSLMSVA---IGGWGGLNQTQLRKIMAYSSIAHMGWM------------TAVMTYnptMALLNLIIYILLTTT 214
Cdd:COG1007  265 AADWQLLLAVLAVLsmtVGNLAALAQTNVKRMLAYSSIAHAGYLllglaagtplgvSAALFY---LLAYLFMNLGAFAVI 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 215 TFMTFMLNSTTTTLSLSHTWNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYM 294
Cdd:COG1007  342 LLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYL 421


                 ..
gi 146330985 295 RL 296
Cdd:COG1007  422 RV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-276 2.05e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 98.15  E-value: 2.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   23 SSHWLMVWIGFEMNMLAILP-VLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSGQWS--------TANPLNPT 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSfdelskalTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   94 TSII---MTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILL-TWQKLAP-----MSILYQISPAINMDLLLSMSLMSVAI 164
Cdd:pfam00361  81 LLLLfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  165 GGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILL---------TTTTFMTFMLNSTTTTLSLSHTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLThglfsaglfLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 146330985  236 KTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSI 276
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWI 281
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 7-296 2.40e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 100.09  E-value: 2.40e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   7 SMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVL-MKKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSGQWS 85
Cdd:MTH00199 100 PILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVaLKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETS 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  86 T----ANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINmdLLLSMSLMS 161
Cdd:MTH00199 180 IqginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVLS 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 162 VAIGGWGGLNQTQLRKIMAYSSIAHMG---WMTAVMTYNPTMALLNLIIYILLTTT---TFMTFMLNSTTTTLSLSHTWN 235
Cdd:MTH00199 258 IIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESIQASLIYMIIYVIMSIcsfSIILSLKLTKGLIVEVSGLSR 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146330985 236 KTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:MTH00199 338 KNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 9-296 6.67e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 93.09  E-value: 6.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985    9 IMATIILGTLIVMTSSHWLMVWIGFEMNMLAILpVLM--KKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSG---- 82
Cdd:TIGR01770 107 LLLFALLGIFLLVSSNDLLSIYLGLELQSLCFY-VLAglKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGslnf 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   83 -----QWSTANPLNP---TTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAI----- 149
Cdd:TIGR01770 186 edlllFLSNGMLNISlllLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  150 --NMDLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGW-MTAVMTynPTMALLNLIIYILLTTTTFMTFMLNSTTT 226
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLA--GTLEGIKAVLFYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  227 TLSLSHTWNKT-----------PLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMR 295
Cdd:TIGR01770 344 LRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  .
gi 146330985  296 L 296
Cdd:TIGR01770 424 V 424
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-296 6.38e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 87.57  E-value: 6.38e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  14 ILGTLIVMTSSHWLMVWIGFEMNMLAiLPVL--MKKYNPRSMEAATKYFLTQATASMLLMLAI--------TINLIYSGQ 83
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLP-LYALaaLRRDRRRSLEAAIKYFVLGALASGFLLYGMsllygatgSLSFAGIAK 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  84 WSTANPLNPT---TSIIMTLA-LAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMS----ILYQISPAINMD--- 152
Cdd:PRK05777 192 ALADGSGNSLlllFGLVFLLVgLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAvllrLLVVAFGGLSEDwqq 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 153 LLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSH 232
Cdd:PRK05777 272 VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMTLGAFGVISLLRRKGGE 351

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146330985 233 TWN---------KTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:PRK05777 352 AESisdfaglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 14-296 1.25e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 71.33  E-value: 1.25e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  14 ILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAI--------TINLIYSGQWS 85
Cdd:COG0651  117 LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVgllygatgTLNMADLAARL 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  86 TANPLNPTT--SIIMTLALAMKLGLSPFHFWVPE-----------VTQGIQLSSGL--ILLTWQKLAPMSILYQISPain 150
Cdd:COG0651  197 AELDPGLLLaaFALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLGT--- 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 151 mdLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTF--------MTFMLN 222
Cdd:COG0651  274 --LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKallflaagAIERAT 351

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146330985 223 STTTTLSLSHTWNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:COG0651  352 GTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-267 8.14e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.12  E-value: 8.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  15 LGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSM---------EAATKYFLTQATASMLLMLAITINLIYSG-QW 84
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGnEG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  85 STANPLNPTTS-------------IIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILyqISPAINM 151
Cdd:MTH00198 279 MLGTILSATLEttnielrqgslgyLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 152 DLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGW------------MTAVMTYNPTMALLNLIIYILLTTTTFMTF 219
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFiligvsagtyesLQASWTYAVTYLVSALASFTVICTLEEFGT 436

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146330985 220 MLNSTTTTLSLSHTWNKT-------------PLLTTTILILMLSLGGLPPLSGFLPKWMII 267
Cdd:MTH00198 437 RTPTSRQRDGSFGNYNLVrrlvdltilsrgqPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 8.54e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 56.50  E-value: 8.54e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 146330985  291 YFYMRLTYSTSLTMFPSVNNMKMKWQFNSMKQTTHLPPLIVLSTLILPMSP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-191 1.05e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 56.49  E-value: 1.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   50 PRSMEAATKYFLTQATASmLLMLAITINLIYSGQWSTA------NPLNPTTSIIMTLAL----AMKLGLSPFHFWVPEV- 118
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGS-LLMLLAILGLYFLGGGTFDllellnLPLPFGVQTWLFLAFfiafAVKVPLFPLHTWLPDAh 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  119 ----TQGIQLSSGLILltwqKLAP---MSILYQISP---AINMDLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:TIGR01972 231 veapTAGSVILAGVLL----KMGTygfLRFNLPLFPdasLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMG 306


                  ...
gi 146330985  189 WMT 191
Cdd:TIGR01972 307 FVL 309
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 50-192 5.64e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 53.93  E-value: 5.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  50 PRSMEAATKYFLTQATASMLLMLAITINLIYSGQWS------TANPLNPTTSII----MTLALAMKLGLSPFHFWVPEV- 118
Cdd:COG1008  157 ERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTfdiaelAAAPLPLTAQLLlflaFFIAFAVKVPMFPFHTWLPDAh 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 119 ----TQGIQLSSGLILltwqKLAPMSIL---YQISP---AINMDLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:COG1008  237 veapTAGSVLLAGVLL----KMGGYGLLrfaLPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312


                 ....
gi 146330985 189 WMTA 192
Cdd:COG1008  313 FVLL 316
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-263 6.20e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.90  E-value: 6.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   9 IMATIILGTLIVMTSSHWLMVWIGFEMnmLAILPVLMKKY---NPRSMEAATKYFLTQATASMLLMLAITINLIYSGQWS 85
Cdd:PRK02504 115 ILLTATLGGMFLSGATELVMIFISLET--LSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGGST 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  86 T----ANPLNPTTSIIMTLAL-------AMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLA----PMSILYQISPAIN 150
Cdd:PRK02504 193 QlsaiALALITSPSLGLALALvfviagiAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFD 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 151 MD---LLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTT 227
Cdd:PRK02504 273 EQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTEAGYASMVFYLLAYLFMNLGAFACVILFS 352

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 146330985 228 LSLSH--------TWNKTPLLTTTILILMLSLGGLPPLSGFLPK 263
Cdd:PRK02504 353 LRTGTdqisdyagLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
27-296 2.16e-06

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 49.18  E-value: 2.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  27 LMVWigFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAI--------TINLIYSGQWSTA---NPLNPTTS 95
Cdd:PRK12663 133 LYVW--FEVMLIASFVLITLGQEREQLRGAIKYVVLNLIGSWLFLLGIgllygtfgTLNMAHIAMRLNDmgdTATLTTIA 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  96 IIMTLALAMKLGLSPFhFWVPEV--TQGIQLSSGLI-LLT----WQKLAPMSILYQISPAINMDLLLSMSLMSVAIGGWG 168
Cdd:PRK12663 211 LLFLLAFGMKAALFPF-MWLPAAyhTPNTEVAALFAaLLTkvgiYALIRVFTLLFPQERELLHPLLATMAAITMVIGALG 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 169 GLNQTQLRKIMAYSSIAHMGWMTA-VMTYNPT-------MALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLL 240
Cdd:PRK12663 290 ALAYKDIRRIAGYQVISSIGFILLgLALGTPAgingaifYLVHDMVVKTALFLIAGSLVRLTGYRSLQYLGGLYRKEPLF 369

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 146330985 241 TTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:PRK12663 370 GALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRI 425
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 43-299 2.12e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 46.24  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  43 VLMKKYNPRSMEAATKYFLTQATASMLLMLAITinLIYsGQWSTAN--------PLNPTTSIIMTLA-----LAMKLGLS 109
Cdd:PRK08376 161 VAFRNDTWEAIEAGIKYMFVGSLASSMVLLGIA--LLY-GQYGTLNmaylavkmSENPTVVAKIALAlfiagLAMKSGAV 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 110 PFHFWVP----EVTQGIqlSSGLILLTWQKL-APMSILYQI-SPAINMD----LLLSMSLMSVAIGGWGGLNQTQLRKIM 179
Cdd:PRK08376 238 PVHMWLPdaypAAPSSI--SAMLLVIKQAGLyALARVLFSIyGPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLL 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 180 AYSSIAHMGWM-----TAVMTY-NPTMALLNLIIYI-----LLTTTTFMTFMLNSTTTTLSLSHTWN---------KTPL 239
Cdd:PRK08376 316 AYHSVSQIGYMllglgVGLAALgDPAMASYGEIALAggiyhIVNHALYKALLFLTAGAVIYETGTRNlnelgglarTMPK 395

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 240 LTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITpTIMAITALLNLYFYMRLTYS 299
Cdd:PRK08376 396 TTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFNPILG-VIAMIGSVLTLASFVKVFHT 454
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-296 2.72e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 45.77  E-value: 2.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  51 RSMEAATKYFLTQATASMLLML-----------AITINLIYSGQWSTANPLNPTTSI---IMTLALAMKLGLSPFHFWVP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYgfswlyglsggEIELQEIVNGLINTQMYNSPGISIaliFITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 117 EVTQG-----------IQLSSGLILLTwqklAPMSILYQISPAINMDLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIA 185
Cdd:CHL00049 239 DVYEGsptpvvaflsvTSKVAASALAT----RIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIG 314

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 186 HMGW-MTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSH--------TWNKTPLLTTTILILMLSLGGLPP 256
Cdd:CHL00049 315 QIGYvIIGIIVGDSNDGYASMITYMLFYIFMNLGTFACIVLFGLRTGTdnirdyagLYTKDPFLALSLALCLLSLGGIPP 394

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 146330985 257 LSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:CHL00049 395 LAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 47-299 4.55e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 44.96  E-value: 4.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  47 KYNPRSMEAATKYFLTQATASMLLMLAI--------TINLI--------YSGQWSTANPLNPTTSIIMTLALAM-----K 105
Cdd:PRK12667 157 RDRGDAVEAAIKYALIGAVGTTLYFLALaflyatfgTLNMAdlsakirgLSFPLTGGLAGNPPLALGVALALALwaftiK 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 106 LGLSPFHFWVPEV-----TQGIQLSSGLILLTwQKLAPMSILYQI-------SPAIN--MDLLLSMSLMSVAIGGWGGLN 171
Cdd:PRK12667 237 AAIFPNHFWLPDAhpaapSPVSAMLSGLVVNV-GAYAIIRFLYTIfgispslIDFRAalSPILIILGAVSAIIGALMMVV 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 172 QTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSH--------TWNKTPLLTTT 243
Cdd:PRK12667 316 QKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTrdidelagLGRKMPIASFA 395

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 146330985 244 ILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYS 299
Cdd:PRK12667 396 FLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 14-307 4.92e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 44.99  E-value: 4.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  14 ILGTLIVMTSSHWLMVWIGFEMNMLA-ILPVLMKKynPRSMEAATKYFLTQATASMLLMLAITINLIYSGQW---STANP 89
Cdd:PRK08668 108 LAGVLGVFLANDLLTLYIFWEIMTFSsFMMVPMGK--KESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFdfaDISQG 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  90 LNPTTSIIMTLALAM--------KLGLSPFHFWVPEV--------------------TQGIQLSSGLILLTwqKLAPMSI 141
Cdd:PRK08668 186 LINDTSTGFALIVFLfllafgvaKAGIFPLHVWAPDAyseapqsfsavlsgqlsklgAYGFLLVLYVLPGT--KLFSEFG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 142 LYQISPAINMdLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGW-------MTAVMTYNPTM-ALLNLIIYILLTT 213
Cdd:PRK08668 264 TYRGVPLFNY-ILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYilvglglGTSLGFAGGLFhVFNHALFKGLFFL 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 214 TTFMTFMLNSTTTTLSLSHTWNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFY 293
Cdd:PRK08668 343 IFAAVIYRTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYV 422

                        330
                 ....*....|....
gi 146330985 294 MRLTYSTSLTMFPS 307
Cdd:PRK08668 423 FRPLAGVFLGQLPS 436
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-298 4.96e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 44.87  E-value: 4.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  49 NPRSMEAATKYFLTQATASMLLMLAI--------TINLIYSGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPE--- 117
Cdd:PRK08375 151 DRRALAAARKYLIVGLIGSTFLLIGVgllygvtgTLNMADLAGALAENPTVVTAFGFVLLALALKAAVFPLHTWLPRayp 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 118 --------------VTQGIQLSSGLILLTWQKLAPMSILYQIspainmdLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSS 183
Cdd:PRK08375 231 aappvvtallsglvTKVAVYALIRIYFTVFGGDFRFALGLGW-------LLAVLALLSMLVGSLAALGQDDVKRVLAYST 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 184 IAHMGWM---TAVMTYNPTMALLN-----LIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLLTTTILILMLSLGGLP 255
Cdd:PRK08375 304 VSQMGYIllgLALLTPLALAAGLLhllhhALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVP 383

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 146330985 256 PLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTY 298
Cdd:PRK08375 384 PTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 234-300 1.54e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 43.60  E-value: 1.54e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146330985 234 WNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQEL--TKNDSIITPTIMAITALLNLYFYMRLTYST 300
Cdd:COG1009  363 RKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAAleAGGLGPLLLAVALLGAFLTAFYSFRLFFLV 431
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-191 1.57e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 43.27  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  50 PRSMEAATKYFL-TQAtaSMLLMLAITINLIYSGQWST---------ANPLNPTTSIIMTLAL----AMKLGLSPFHFWV 115
Cdd:PRK05846 157 KNRIYAATKFFLyTLL--GSLLMLVAIIYLVVVYYNATgtfdiadllNLPLPPGVQYWLFLAFfiafAVKMPMFPLHTWL 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 116 PEV-----TQGIQLSSGLILltwqKLAP---MSILYQISPAINMD---LLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSI 184
Cdd:PRK05846 235 PDAhvqapTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSI 310


                 ....*..
gi 146330985 185 AHMGWMT 191
Cdd:PRK05846 311 SHMGFVT 317
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-191 2.58e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 42.73  E-value: 2.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 100 LALAMKLGLSPFHFWVPE-----------VTQGIQLS---SGLILLTWQKLAPMSILYqiSPainmdLLLSMSLMSVAIG 165
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQahveapvagsvILAGVLLKlggYGFIRFSWPLLPEASEYF--SP-----LIQTLSLLAIIYG 286

                         90       100
                 ....*....|....*....|....*.
gi 146330985 166 GWGGLNQTQLRKIMAYSSIAHMGWMT 191
Cdd:MTH00217 287 SLTTCRQVDLKRIIAYSSVAHMGLVT 312
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 100-188 1.21e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.68  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 100 LALAMKLGLSPFHFWVPE-----------VTQGIQLS---SGLILLTWQKLaPMSIlYQISPAInmdllLSMSLMSVAIG 165
Cdd:MTH00226 238 LAMAVKIPIFPFHIWLPKahveapvagsvLLAGILLKlggYGLVRLSWPIL-PLGA-QNLAPAV-----IAMGIVGIVYG 310

                         90       100
                 ....*....|....*....|...
gi 146330985 166 GWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:MTH00226 311 SFATCRQIDVKRLVAYSSVAHMG 333
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 238-296 2.23e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 39.55  E-value: 2.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 146330985 238 PLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRL 296
Cdd:PRK07691 370 PVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIKI 428
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 8-197 3.55e-03

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 38.95  E-value: 3.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985   8 MIMATIILGTLIVM-TSSHWLMVWIGFEMNMLAIL-PVLMKKYNPRSMEAATKYFLTQATASMLLMLAI--------TIN 77
Cdd:MTH00014  93 MTNILILNLILLLTfSASNLLMFYIFFEASLIPTLfLILGWGYQPERLQASFYLMIYTVTASLPLLMSIllifytnnSLS 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  78 LIYSGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPE------VTQGIQLSSGLILLTWQKLAPMSILYQISPAINM 151
Cdd:MTH00014 173 MLMSSMEPPSIYLMNLWWLITILAFMVKMPLYTVHLWLPKahveapVAGSMILAGILLKLGGYGLLRMSSLFMHINKSLS 252

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 146330985 152 DLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYN 197
Cdd:MTH00014 253 APFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSN 298
PRK12650 PRK12650
DUF4040 family protein;
78-263 4.31e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.87  E-value: 4.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985  78 LIYSGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMD----- 152
Cdd:PRK12650 194 ILHSDVWAEKPGLTTVVAVLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVavwnw 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 153 LLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTT------ 226
Cdd:PRK12650 274 LLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVdhqagt 353

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 146330985 227 --TLSLSHTWNKTPLLTTTILILMLSLGGLPPLSGFLPK 263
Cdd:PRK12650 354 rdIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGFVSK 392
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-191 8.92e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 37.74  E-value: 8.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146330985 100 LALAMKLGLSPFHFWVPE-----------VTQGIQLS---SGLILLTWQKLAPMSILYqiSPAINMdlllsMSLMSVAIG 165
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQahveapvagsvILAGILLKlggYGFLRFSWPLFPAASEYF--APLIVM-----LSVIAVIYG 289

                         90       100
                 ....*....|....*....|....*.
gi 146330985 166 GWGGLNQTQLRKIMAYSSIAHMGWMT 191
Cdd:MTH00204 290 SLTTCRQVDFKRLIAYSSVAHMGLVP 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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