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Conserved domains on  [gi|146289863|sp|Q330A4|]
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RecName: Full=NADH-ubiquinone oxidoreductase chain 2; AltName: Full=NADH dehydrogenase subunit 2

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 1.70e-177

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 495.52  E-value: 1.70e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 146289863 321 KPTANLSPLIILSTLILPLSPMLALLE 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 1.70e-177

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 495.52  E-value: 1.70e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 146289863 321 KPTANLSPLIILSTLILPLSPMLALLE 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 6-296 2.48e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 2.48e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   6 FTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSG-- 82
Cdd:COG1007  104 FYALLLFATLGMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGsl 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  83 ---------QWSMTKPLTSTTSIIMTLA-LAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLD 152
Cdd:COG1007  184 nlagiaaalAAGGANSPLLLLGLVLVLAgLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 153 LLLLMSLLSI-------LVGGWGGLNQTQLRKIMAYSSIAHMGWM-TAIMVYNPTM---ALLNLVIYILLTT----TTFM 217
Cdd:COG1007  264 LAADWQLLLAvlavlsmTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGvsaALFYLLAYLFMNLgafaVILL 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 218 MLMMNSSTTTLS-LSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRL 296
Cdd:COG1007  344 LSRKGGEAEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 25-268 1.40e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 98.54  E-value: 1.40e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   25 HWVMAWIGFEMNMLAVIP-ILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWSMT-----------KPLTS 92
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDelskaltgglnSSGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   93 TTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILL-TWQKLAP-----MSILYQISPTINLDLLLLMSLLSILVGG 166
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  167 WGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILL---------TTTTFMMLMMNSSTTTLSLSHMWNKT 237
Cdd:pfam00361 163 LAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLThglfsaglfLCAGSVIYRRVHTRNIRDYGGLAKTM 242

                         250       260       270
                  ....*....|....*....|....*....|.
gi 146289863  238 PLLTTAILTIMLSLGGLPPLSGFTPKWMIIQ 268
Cdd:pfam00361 243 PILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-337 3.03e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.47  E-value: 3.03e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863    6 FTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSG-- 82
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   83 ----------QWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTI--- 149
Cdd:TIGR01770 184 nfedlllflsNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  150 ----NLDLLLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGW------------MTAIMVYNPTMALLNLVIYILLTT 213
Cdd:TIGR01770 264 fseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiligllagtlegIKAVLFYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  214 TTFMMLMMNSSTTTLSLSHMWNktPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFY 293
Cdd:TIGR01770 344 LRSYKDEWIEYISDFAGLFKTN--PILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYY 421

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 146289863  294 MRLtystSLTMFPSTNNMKIKWQFSHKKPTANLSPLIILSTLIL 337
Cdd:TIGR01770 422 LRV----VKVMYFDKPERRIPSNPQSKAQSLLLSISALFILFLG 461
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 1.70e-177

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 495.52  E-value: 1.70e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 146289863 321 KPTANLSPLIILSTLILPLSPMLALLE 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 5.66e-124

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 359.89  E-value: 5.66e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTiNLDLLLLMSLL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*..
gi 146289863 321 KPTANLSPLIILSTLILPLSP-MLALL 346
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPaILALL 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-343 3.80e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 342.57  E-value: 3.80e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|...
gi 146289863 321 KPTaNLSPLIILSTLILPLSPML 343
Cdd:MTH00112 321 KNT-LTATLTTLSTLLLPLSPMI 342
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 2.93e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 329.96  E-value: 2.93e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHk 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKN- 319

                        330       340
                 ....*....|....*....|....*.
gi 146289863 321 KPTANLSPLIILSTLILPLSPMLALL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-339 7.06e-90

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 273.34  E-value: 7.06e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|....
gi 146289863 321 KPTAN-----LSPLIILSTLILPL 339
Cdd:MTH00041 321 ITVYGvilsiLSSISILGLLLIPL 344
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 4.25e-88

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 268.38  E-value: 4.25e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQfSHK 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWR-TKS 319

                        330       340
                 ....*....|....*....|....*.
gi 146289863 321 KPTANLSPLIILSTLILPLSPMLALL 346
Cdd:MTH00200 320 NSNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-346 8.67e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 182.33  E-value: 8.67e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   1 MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLvy 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNM-- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 sgqwSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQIsptINLDLLLLMSLL 160
Cdd:MTH00160  80 ----LNLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 241 TTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYStslTMFPSTNNMKIKWQFSHK 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYS---SLMLNYNKNKWNLKKKKN 309

                        330       340
                 ....*....|....*....|....*.
gi 146289863 321 KPTANLSPLIILSTLILPLSPMLALL 346
Cdd:MTH00160 310 KFSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 8-318 6.55e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 169.68  E-value: 6.55e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   8 MILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWSMt 87
Cdd:MTH00144   8 LFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  88 kpltsttSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMS-LLSILVGG 166
Cdd:MTH00144  87 -------MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVIsVLSALVGS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 167 WGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMwNKTPLLTTAILT 246
Cdd:MTH00144 160 IGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIIS 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146289863 247 IMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFS 318
Cdd:MTH00144 239 LLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNS 310
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 12-341 6.40e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 159.17  E-value: 6.40e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  12 TVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVInlvysgQWSMTKPLT 91
Cdd:MTH00011  14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  92 STTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLLSILVGGWGGLN 171
Cdd:MTH00011  88 NITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 172 QTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLLTTAILTIMLSL 251
Cdd:MTH00011 168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 252 GGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLtystsltMFPSTNNMKIKWQFSHKKPTANLSPLII 331
Cdd:MTH00011 248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNL-------IFNFMYLSPTFSSLKSAPYEPKTKILIS 320

                        330
                 ....*....|
gi 146289863 332 LSTLILPLSP 341
Cdd:MTH00011 321 MCTLSLGLIP 330
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-300 8.23e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 132.49  E-value: 8.23e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   8 MILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLvysgqwsMT 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF-------SN 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  88 KPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPtiNLDLLLLMSLLSILVGGW 167
Cdd:MTH00197  75 LYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 168 GGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLLTTAILTI 247
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 146289863 248 MLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYST 300
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-296 2.36e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 104.73  E-value: 2.36e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  13 VMLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIV-------------INL 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  79 VYSGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINldLLLLMS 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 159 LLSILVGGWGGLNQTQLRKIMAYSSIAHMG---WMTAIMVYNPTMA-LLNLVIYILLTTTTFMMLMMNSSTTTL--SLSH 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFESIQAsLVYLFIYIIMSICVFSIILALNVYKNLiiEFSG 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146289863 233 MWNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRL 296
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 6-296 2.48e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 2.48e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   6 FTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSG-- 82
Cdd:COG1007  104 FYALLLFATLGMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGsl 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  83 ---------QWSMTKPLTSTTSIIMTLA-LAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLD 152
Cdd:COG1007  184 nlagiaaalAAGGANSPLLLLGLVLVLAgLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 153 LLLLMSLLSI-------LVGGWGGLNQTQLRKIMAYSSIAHMGWM-TAIMVYNPTM---ALLNLVIYILLTT----TTFM 217
Cdd:COG1007  264 LAADWQLLLAvlavlsmTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGvsaALFYLLAYLFMNLgafaVILL 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 218 MLMMNSSTTTLS-LSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRL 296
Cdd:COG1007  344 LSRKGGEAEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 6-345 4.44e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 102.40  E-value: 4.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   6 FTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQW 84
Cdd:MTH00199  99 SPILILIVALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGET 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  85 SM----TKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINldLLLLMSLL 160
Cdd:MTH00199 179 SIqginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVL 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 161 SILVGGWGGLNQTQLRKIMAYSSIAHMG---WMTAIMVYNPTMA-LLNLVIYILLTTTTFMMLMMNSSTTTL--SLSHMW 234
Cdd:MTH00199 257 SIIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESIQAsLIYMIIYVIMSICSFSIILSLKLTKGLivEVSGLS 336

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 235 NKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLtysTSLTMFPSTNNMKIK 314
Cdd:MTH00199 337 RKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV---VQIIYFQADYSILIW 413

                        330       340       350
                 ....*....|....*....|....*....|..
gi 146289863 315 WQFSHKKPTANLSP-LIILSTLILPLSPMLAL 345
Cdd:MTH00199 414 QKVLKKEERLDLSKsILIGVTFFIILFLMISP 445
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 25-268 1.40e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 98.54  E-value: 1.40e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   25 HWVMAWIGFEMNMLAVIP-ILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWSMT-----------KPLTS 92
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDelskaltgglnSSGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   93 TTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILL-TWQKLAP-----MSILYQISPTINLDLLLLMSLLSILVGG 166
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  167 WGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILL---------TTTTFMMLMMNSSTTTLSLSHMWNKT 237
Cdd:pfam00361 163 LAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLThglfsaglfLCAGSVIYRRVHTRNIRDYGGLAKTM 242

                         250       260       270
                  ....*....|....*....|....*....|.
gi 146289863  238 PLLTTAILTIMLSLGGLPPLSGFTPKWMIIQ 268
Cdd:pfam00361 243 PILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-337 3.03e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.47  E-value: 3.03e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863    6 FTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSG-- 82
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   83 ----------QWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTI--- 149
Cdd:TIGR01770 184 nfedlllflsNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  150 ----NLDLLLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGW------------MTAIMVYNPTMALLNLVIYILLTT 213
Cdd:TIGR01770 264 fseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiligllagtlegIKAVLFYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  214 TTFMMLMMNSSTTTLSLSHMWNktPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFY 293
Cdd:TIGR01770 344 LRSYKDEWIEYISDFAGLFKTN--PILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYY 421

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 146289863  294 MRLtystSLTMFPSTNNMKIKWQFSHKKPTANLSPLIILSTLIL 337
Cdd:TIGR01770 422 LRV----VKVMYFDKPERRIPSNPQSKAQSLLLSISALFILFLG 461
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
6-296 8.84e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 84.10  E-value: 8.84e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   6 FTMILLTVmLGTAIVMTTSHWVMAWIGFEMNMLAV-IPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSG-- 82
Cdd:PRK05777 106 YLLVLFAL-LGMMVMVSANDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGsl 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  83 ----------QWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQI------- 145
Cdd:PRK05777 185 sfagiakalaDGSGNSLLLLFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafgg 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 146 SPTINLDLLLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGWM-TAIMVYNPTM---ALLNLVIYILLTT----TTFM 217
Cdd:PRK05777 265 LSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlVGLAAGTAEGysaVLFYLLAYLFMTLgafgVISL 344

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 218 MLMMNSSTTTLS-LSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRL 296
Cdd:PRK05777 345 LRRKGGEAESISdFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 5-296 8.14e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 77.88  E-value: 8.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   5 IFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQW 84
Cdd:COG0651  108 RFYPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTL 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  85 SMT----------KPLTSTTSIIMTLALAMKLGLAPFHFWVPE-----------VTQGVQLSSGL--ILLTWQKLAPMSI 141
Cdd:COG0651  188 NMAdlaarlaeldPGLLLAAFALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADP 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 142 LYQISPTInldllLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMML-- 219
Cdd:COG0651  268 ALFLGTLL-----LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKALLfl 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 220 ---MMNSSTTTLSLSHM---WNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFY 293
Cdd:COG0651  343 aagAIERATGTRDLDKLgglGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYF 422


                 ...
gi 146289863 294 MRL 296
Cdd:COG0651  423 VRI 425
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 1.80e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 58.42  E-value: 1.80e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 146289863  291 YFYMRLTYSTSLTMFPSTNNMKIKWQFSHKKPTANLSPLIILSTLILPLSP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-267 2.37e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.88  E-value: 2.37e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   9 ILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAVIPILMKKYNPRSM---------EASTKYFLTQATASMLLMLAIVINLV 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  80 YSGQWSMTKPLTSTT--------------SIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILyqI 145
Cdd:MTH00198 273 FTGNEGMLGTILSATlettnielrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--T 350

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 146 SPTINLDLLLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMG-----------------WMTAIMVYNPTMALLNLV-- 206
Cdd:MTH00198 351 SLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGfiligvsagtyeslqasWTYAVTYLVSALASFTVIct 430

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146289863 207 ------IYILLTTTTFMMLMMNSSTTTLSLSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMII 267
Cdd:MTH00198 431 leefgtRTPTSRQRDGSFGNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
6-260 1.60e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 58.91  E-value: 1.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   6 FTMILLTVMLGTAIVMTTSHWVMAWIGFEMnmLAVIPILMKKY---NPRSMEASTKYFLTQATASMLLMLAIviNLVY-- 80
Cdd:PRK02504 112 FAAILLTATLGGMFLSGATELVMIFISLET--LSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGS--SLLYgl 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 -SGQWSMTK---PLTSTTSIIMTLAL-------AMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLA----PMSILYQI 145
Cdd:PRK02504 188 sGGSTQLSAialALITSPSLGLALALvfviagiAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTA 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 146 SPTINL---DLLLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTT------- 215
Cdd:PRK02504 268 FPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTEAGYASMVFYLLAYLFMnlgafac 347

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 146289863 216 FMMLMMNSSTTTLS-LSHMWNKTPLLTTAILTIMLSLGGLPPLSGF 260
Cdd:PRK02504 348 VILFSLRTGTDQISdYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGF 393
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 50-267 5.44e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 57.40  E-value: 5.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  50 PRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWS------MTKPLTSTTSII----MTLALAMKLGLAPFHFWVPEV- 118
Cdd:COG1008  157 ERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTfdiaelAAAPLPLTAQLLlflaFFIAFAVKVPMFPFHTWLPDAh 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 119 ----TQGVQLSSGLIL----------------LTWQKLAPM-------SILYqisptinldllllmsllsilvGGWGGLN 171
Cdd:COG1008  237 veapTAGSVLLAGVLLkmggygllrfalplfpEASAYFAPLlaalgviGIIY---------------------GALVALA 295

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 172 QTQLRKIMAYSSIAHMGWMT-AIMVYNPT---------------MALLNLVIYILLttttfmmlmmnSSTTTLSLSHM-- 233
Cdd:COG1008  296 QTDLKRLIAYSSVSHMGFVLlGIFALNPLglqgavlqmvshgliTAALFLLVGVLY-----------DRTHTRDIADLgg 364

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 146289863 234 -WNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMII 267
Cdd:COG1008  365 lAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVL 399
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-339 1.21e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 56.10  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   50 PRSMEASTKYFLTQATASmLLMLAIVINLVYSGQWS------MTKPLTSTTSIIMTLAL----AMKLGLAPFHFWVPEV- 118
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGS-LLMLLAILGLYFLGGGTfdllelLNLPLPFGVQTWLFLAFfiafAVKVPLFPLHTWLPDAh 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  119 ----TQGVQLSSGLILltwqKLAP---MSILYQISP---TINLDLLLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:TIGR01972 231 veapTAGSVILAGVLL----KMGTygfLRFNLPLFPdasLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMG 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  189 WMTAIMVYNPTMALLNLVIY-----ILLTTTTFMMLMMNSSTTTLSLSHM---WNKTPLLTTAILTIMLSLGGLPPLSGF 260
Cdd:TIGR01972 307 FVLLGIFSFNELGISGAVFQmishgLITAALFLLVGVLYERAHTRDIAKYgglANKMPVLAAFFMLFAMASLGLPGTSGF 386

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146289863  261 TPKWMIIQELTKNDnmIMPTIMAVMALLnlyfymrLTYSTSLTMFPSTNNMKIKWQFSHKKPTANLSPLIILSTLILPL 339
Cdd:TIGR01972 387 VGEFLILLGSFKVN--PVVAFLAALGIV-------LAAAYMLTLYKRVFFGELSNPEVAEFPDLNGREIAVLAPLVVLI 456
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
33-337 2.04e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 52.26  E-value: 2.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  33 FEMNMLAVIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWSM------------TKPLTsTTSIIMTL 100
Cdd:PRK12663 137 FEVMLIASFVLITLGQEREQLRGAIKYVVLNLIGSWLFLLGIGLLYGTFGTLNMahiamrlndmgdTATLT-TIALLFLL 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 101 ALAMKLGLAPFhFWVPEV--TQGVQLSSGLI-LLT----WQKLAPMSILYQISPTINLDLLLLMSLLSILVGGWGGLNQT 173
Cdd:PRK12663 216 AFGMKAALFPF-MWLPAAyhTPNTEVAALFAaLLTkvgiYALIRVFTLLFPQERELLHPLLATMAAITMVIGALGALAYK 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 174 QLRKIMAYSSIAHMGWMTA-IMVYNPT---------------MALLNLVIYILLTTTtfmmlmmnSSTTTLSLSHMWNKT 237
Cdd:PRK12663 295 DIRRIAGYQVISSIGFILLgLALGTPAgingaifylvhdmvvKTALFLIAGSLVRLT--------GYRSLQYLGGLYRKE 366

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 238 PLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTystsLTMFPSTNNMKIKwqF 317
Cdd:PRK12663 367 PLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIF----FLAYWGDKDGEEV--N 440

                        330       340
                 ....*....|....*....|
gi 146289863 318 SHKKPTANLSPLIILSTLIL 337
Cdd:PRK12663 441 FKPIPLYRKLPLSILAVVVI 460
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-260 2.12e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 52.31  E-value: 2.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  51 RSMEASTKYFLTQATASMLLMLA----------------IVINLVYSGqwsMTKPLTSTTSII-MTLALAMKLGLAPFHF 113
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGfswlyglsggeielqeIVNGLINTQ---MYNSPGISIALIfITVGIGFKLSLAPFHQ 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 114 WVPEVTQG-----------VQLSSGLILLTwqklAPMSILYQISPTINLDLLLLMSLLSILVGGWGGLNQTQLRKIMAYS 182
Cdd:CHL00049 236 WTPDVYEGsptpvvaflsvTSKVAASALAT----RIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYS 311

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 183 SIAHMGW-MTAIMVYNP----TMALLNLVIYILLTTTTFMMLMMNSSTTTLS----LSHMWNKTPLLTTAILTIMLSLGG 253
Cdd:CHL00049 312 SIGQIGYvIIGIIVGDSndgyASMITYMLFYIFMNLGTFACIVLFGLRTGTDnirdYAGLYTKDPFLALSLALCLLSLGG 391


                 ....*..
gi 146289863 254 LPPLSGF 260
Cdd:CHL00049 392 IPPLAGF 398
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-282 3.78e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 51.54  E-value: 3.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863   2 NPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLA--VIPILMKKYNprsMEASTKYFLTQATASMLLMLAIVINLV 79
Cdd:PRK08668  96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSsfMMVPMGKKES---RKASLKYFVLSAIGAYAMLYAIFLIYA 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  80 YSGQWSMT---KPLTSTTSIIMTLALAM--------KLGLAPFHFWVPEV------TQGVQLSSGLI------------L 130
Cdd:PRK08668 173 KTGTFDFAdisQGLINDTSTGFALIVFLfllafgvaKAGIFPLHVWAPDAyseapqSFSAVLSGQLSklgaygfllvlyV 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 131 LTWQKLAPMSILYQISPTINLDLLLLMSLLSIlVGGWGGLNQTQLRKIMAYSSIAHMGW-------MTAIMVYNPTMALL 203
Cdd:PRK08668 253 LPGTKLFSEFGTYRGVPLFNYILAWLGNISII-VGTLMAILQEDIKKLIAYSSVANGGYilvglglGTSLGFAGGLFHVF 331

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 204 NLVIYILLTTTTFMMLMMNSSTTTLS-LSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIM 282
Cdd:PRK08668 332 NHALFKGLFFLIFAAVIYRTGTTKISeMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMA 411
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 48-337 4.28e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 51.25  E-value: 4.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  48 YNPRSMEASTKYFLTQATASMLLMLAI--------VINLVYSGQwSMTKPLTSTTSIIMTL---ALAMKLGLAPFHFWVP 116
Cdd:PRK08376 166 DTWEAIEAGIKYMFVGSLASSMVLLGIallygqygTLNMAYLAV-KMSENPTVVAKIALALfiaGLAMKSGAVPVHMWLP 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 117 EVTQGVQLSSGLILLTWQK---LAPMSILYQI-SPTINLDL----LLLMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:PRK08376 245 DAYPAAPSSISAMLLVIKQaglYALARVLFSIyGPAINLATvgwvIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIG 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 189 WM-----TAIMVY-NPTMA-------------LLNLVIYILLTTTTFMMLMMNSSTTTLS-LSHMWNKTPLLTTAILTIM 248
Cdd:PRK08376 325 YMllglgVGLAALgDPAMAsygeialaggiyhIVNHALYKALLFLTAGAVIYETGTRNLNeLGGLARTMPKTTIAFLIGA 404

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 249 LSLGGLPPLSGFTPKWMIIqELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMfPSTNNMKIKwqfshKKPTANLSP 328
Cdd:PRK08376 405 AAIVGLPPFNGFASKWLIY-ESSALFNPILGVIAMIGSVLTLASFVKVFHTAFFGP-PSEKVMNVK-----EPPKPMLVP 477


                 ....*....
gi 146289863 329 LIILSTLIL 337
Cdd:PRK08376 478 MLILAIAII 486
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-298 9.68e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 50.26  E-value: 9.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  49 NPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWSMT--------KPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQ 120
Cdd:PRK08375 151 DRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMAdlagalaeNPTVVTAFGFVLLALALKAAVFPLHTWLPRAYP 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 121 GVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSLLSIL----------VGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK08375 231 AAPPVVTALLSGLVTKVAVYALIRIYFTVFGGDFRFALGLGWLlavlallsmlVGSLAALGQDDVKRVLAYSTVSQMGYI 310

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 191 -------TAIMVYNPTMALLNLVIYILLTTTTFMMLMMNSSTTTLS-LSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTP 262
Cdd:PRK08375 311 llglallTPLALAAGLLHLLHHALMKGALFLAAGAIEVTYGTRRLSeLSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVS 390

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 146289863 263 KWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTY 298
Cdd:PRK08375 391 KWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 47-341 1.46e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 49.58  E-value: 1.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  47 KYNPRSMEASTKYFLTQATASMLLMLAIVI--------------NLVYSGQWSMTKPLTSTTSIIMTLALAM-------K 105
Cdd:PRK12667 157 RDRGDAVEAAIKYALIGAVGTTLYFLALAFlyatfgtlnmadlsAKIRGLSFPLTGGLAGNPPLALGVALALalwaftiK 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 106 LGLAPFHFWVPEV-----------TQGVQLSSG-------LILLTWQKLAPMSILYQISPTInldllLLMSLLSILVGGW 167
Cdd:PRK12667 237 AAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirfLYTIFGISPSLIDFRAALSPIL-----IILGAVSAIIGAL 311

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 168 GGLNQTQLRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNS--------STTTLSLSHMWNKTPL 239
Cdd:PRK12667 312 MMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASgvfihaagTRDIDELAGLGRKMPI 391

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 240 LTTAILTIMLSLGGLPPLSGFTPKWMIIQELTKNDNMIMPTIMAVMALLNLYFYMRLTYSTSLTMFPSTNNMKIKWQFSH 319
Cdd:PRK12667 392 ASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSLFFGKPKSGEEVEHKESPSM 471

                        330       340
                 ....*....|....*....|..
gi 146289863 320 KKPTANLSPLIILSTLILPLSP 341
Cdd:PRK12667 472 SVVILVLALAVLILGILALFLP 493
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 49-300 5.35e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 48.22  E-value: 5.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  49 NPRSMEASTKYFLTQATASMLLMLAIVINLVYSGQWSMTK-------PLTSTTSIIMTLALAM----KLGLAPFHFWVPE 117
Cdd:COG1009  157 KPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSEllaaaptILSSPLLTLILLLLLLgafgKSAQFPLHFWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 118 -----------------VTQGVQLssglilltwqkLAPMSILYQISPTInLDLLLLMSLLSILVGGWGGLNQTQLRKIMA 180
Cdd:COG1009  237 amegptpvsallhaatmVKAGVYL-----------LARLSPLFALSPVW-LTVVAIIGAITALFAALIALAQTDIKRVLA 304

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 181 YSSIAHMGWMTA-------------IMVYNPTMALLNLVIYILLTtttfmmlmmnsSTTTLSLSHM---WNKTPLLTTAI 244
Cdd:COG1009  305 YSTVSQLGYMFLalgvgayvaalfhLLTHAFFKALLFLGAGSVIH-----------ATGTRDIRKMgglRKKMPITAITF 373

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 146289863 245 LTIMLSLGGLPPLSGFTPKWMIIQEL--TKNDNMIMPTIMAVMALLNLYFYMRLTYST 300
Cdd:COG1009  374 LIGALSLAGIPPFAGFFSKEAILEAAleAGGLGPLLLAVALLGAFLTAFYSFRLFFLV 431
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 175-267 1.94e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 40.10  E-value: 1.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 175 LRKIMAYSSIAHMGWMTAIMVYNPTMALLNLVIYILLTTTTFMMLMMNS--------STTTLSLSHMWNKTPLLTTAILT 246
Cdd:PRK12662 303 IKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSgsisyhfgTTKLEDCLNLWKSMPKITLAFVL 382

                         90       100
                 ....*....|....*....|.
gi 146289863 247 IMLSLGGLPPLSGFTPKWMII 267
Cdd:PRK12662 383 LSLSLIGMPPTSGFVAKWYIL 403
PRK12650 PRK12650
DUF4040 family protein;
81-263 5.45e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.87  E-value: 5.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863  81 SGQWSMTKPLTSTTSIIMTLALAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISP-----TINLDLLL 155
Cdd:PRK12650 197 SDVWAEKPGLTTVVAVLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPvfhdvAVWNWLLI 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146289863 156 LMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGW------------MTAIMVYNPTMALLNLVIYILLTTTTFMMlmmnS 223
Cdd:PRK12650 277 IVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWivatigvgtpfaLTAAVVHTLAHALFKSSLFMLIGVVDHQA----G 352

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 146289863 224 STTTLSLSHMWNKTPLLTTAILTIMLSLGGLPPLSGFTPK 263
Cdd:PRK12650 353 TRDIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGFVSK 392
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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