NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1440416638|emb|SUI42393|]
View 

Invasin [Serratia quinivorans]

Protein Classification

Ig-like domain-containing protein( domain architecture ID 10652438)

bacterial immunoglobulin (Ig)-like domain-containing protein may be a cell surface protein and may play a vital role in host-pathogen interactions; similar to Bacteroides fragilis putative transglutaminase-family protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
BID_1 smart00634
Bacterial Ig-like domain (group 1);
58-138 5.94e-12

Bacterial Ig-like domain (group 1);


:

Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 59.65  E-value: 5.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   58 TGATANGKDINAITAKVTDANGNPLANQTVTFNVAEG--ATITPHEVQTGADGNAGATVTSLKAGTYAVTAEVNGKGTSK 135
Cdd:smart00634  10 DTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGgaLTLSKGTATTDANGIATVTLTSTTAGVYTVTASLENGSSSV 89


                   ...
gi 1440416638  136 NTT 138
Cdd:smart00634  90 KQV 92
 
Name Accession Description Interval E-value
BID_1 smart00634
Bacterial Ig-like domain (group 1);
58-138 5.94e-12

Bacterial Ig-like domain (group 1);


Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 59.65  E-value: 5.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   58 TGATANGKDINAITAKVTDANGNPLANQTVTFNVAEG--ATITPHEVQTGADGNAGATVTSLKAGTYAVTAEVNGKGTSK 135
Cdd:smart00634  10 DTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGgaLTLSKGTATTDANGIATVTLTSTTAGVYTVTASLENGSSSV 89


                   ...
gi 1440416638  136 NTT 138
Cdd:smart00634  90 KQV 92
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 62-126 1.46e-10

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 54.87  E-value: 1.46e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1440416638  62 ANGKDINAITAKVTDANGNPLANQTVTFNVAEGATITPhEVQTGADGNAGATVTSLKAGTYAVTA 126
Cdd:pfam02369   1 ADGVDTNTVTATVTDANGNPVPGATVTFSASGGTLSAS-SGTTDANGQATVTLTSTKAGTVTVTA 64
Ve_IatC_Nterm NF040978
inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve ...
 42-193 7.77e-05

inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve secretion protein) IatC contains a central region that is variable in the number of repeats seen, and averages about 3000 amino acids in length. This HMM describes a mostly non-repetitive region N-teminal to the architectural differences from different repeat counts are seen. IatC can contribute to biofilm formation.


Pssm-ID: 468908 [Multi-domain]  Cd Length: 1065  Bit Score: 42.87  E-value: 7.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   42 ADSDTAEITDGNLSVGTGATAngKDINAITAKVTDANGNPLANQTVTFNVAEGATITPHE----VQTGADGNAGATVTSL 117
Cdd:NF040978   736 GDKDTAKIAAMQITANNAVAR--RDHNTVAVTVRDVHQNLLQGQNVTFTVVNGAAVFADPnggiVTTDKDGIASVNLASD 813

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1440416638  118 KAGTYAVTAEVNGKGTSKNTTFVADKDSAgiADGDLAVGDNNAVADGKSTDSVTakVTDANGNPVSGVeVSFLAGN 193
Cdd:NF040978   814 QAVNSLIKAEINGSSQSVEVSFITGDISQ--LTSTIKTDDVSYTAGGKIKVSVT--LMDEQKNLVKGM-ASLLAGS 884
Ve_IatC_Nterm NF040978
inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve ...
 23-184 7.91e-04

inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve secretion protein) IatC contains a central region that is variable in the number of repeats seen, and averages about 3000 amino acids in length. This HMM describes a mostly non-repetitive region N-teminal to the architectural differences from different repeat counts are seen. IatC can contribute to biofilm formation.


Pssm-ID: 468908 [Multi-domain]  Cd Length: 1065  Bit Score: 39.79  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   23 YTVTAKVNDSEA----KKDAHFVADSDTAEITDGNLSVGTGAT-ANGKDINAITAKVTDANGNPLANQTVTFNVAEGATI 97
Cdd:NF040978   506 YPIAVTAEDSKGnfsrREESMVVVEKPTLSLADSTLSVDLQILlADGKSISTLTYTARDSSGKPIPGMTLKTHAKGLQDF 585

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   98 TPHEVQTGADGNAGATVTSLK-AGTYAVTAEVNGKGTSKNTTFVAD-KDSAGIADGDLAVGDNNAVADGKSTDSVTAKvt 175
Cdd:NF040978   586 ALSEWKDNGNGTYTQIVTAGKtSGALSLMPQFNGDDIAKTPALIAIvANMASRADSMIETDQDNYVAGKPIGVKVTLK-- 663


                   ....*....
gi 1440416638  176 DANGNPVSG 184
Cdd:NF040978   664 DDNGNGVTG 672
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 54-210 9.23e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 36.56  E-value: 9.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   54 LSVGTGATANGKDInaITAKVTDANGNPLANQTVTFNVAEGATITPHEVQTGADGNagaTVTSLKAGTYAVTAEVNGKGT 133
Cdd:NF038112  1258 LVVSDGTKTSAPDT--VTVLVRNVNRAPVAVAGAPATVDERSTVTLDGSGTDADGD---ALTYAWTQTSGPAVTLTGATT 1332

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1440416638  134 SKnTTFVADKDSAGIA-DGDLAVGDNNAVAdgksTDSVTAKVTDANGNPVSGVEVSFLAGNDATVVTETVTTGADGMA 210
Cdd:NF038112  1333 AT-ATFTAPEVTADTQlTFTLTVSDGTASA----TDTVTVTVRNVNRAPVANAGADQTVDERSTVTLSGSATDPDGDA 1405
 
Name Accession Description Interval E-value
BID_1 smart00634
Bacterial Ig-like domain (group 1);
58-138 5.94e-12

Bacterial Ig-like domain (group 1);


Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 59.65  E-value: 5.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   58 TGATANGKDINAITAKVTDANGNPLANQTVTFNVAEG--ATITPHEVQTGADGNAGATVTSLKAGTYAVTAEVNGKGTSK 135
Cdd:smart00634  10 DTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGgaLTLSKGTATTDANGIATVTLTSTTAGVYTVTASLENGSSSV 89


                   ...
gi 1440416638  136 NTT 138
Cdd:smart00634  90 KQV 92
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 62-126 1.46e-10

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 54.87  E-value: 1.46e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1440416638  62 ANGKDINAITAKVTDANGNPLANQTVTFNVAEGATITPhEVQTGADGNAGATVTSLKAGTYAVTA 126
Cdd:pfam02369   1 ADGVDTNTVTATVTDANGNPVPGATVTFSASGGTLSAS-SGTTDANGQATVTLTSTKAGTVTVTA 64
Ve_IatC_Nterm NF040978
inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve ...
 42-193 7.77e-05

inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve secretion protein) IatC contains a central region that is variable in the number of repeats seen, and averages about 3000 amino acids in length. This HMM describes a mostly non-repetitive region N-teminal to the architectural differences from different repeat counts are seen. IatC can contribute to biofilm formation.


Pssm-ID: 468908 [Multi-domain]  Cd Length: 1065  Bit Score: 42.87  E-value: 7.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   42 ADSDTAEITDGNLSVGTGATAngKDINAITAKVTDANGNPLANQTVTFNVAEGATITPHE----VQTGADGNAGATVTSL 117
Cdd:NF040978   736 GDKDTAKIAAMQITANNAVAR--RDHNTVAVTVRDVHQNLLQGQNVTFTVVNGAAVFADPnggiVTTDKDGIASVNLASD 813

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1440416638  118 KAGTYAVTAEVNGKGTSKNTTFVADKDSAgiADGDLAVGDNNAVADGKSTDSVTakVTDANGNPVSGVeVSFLAGN 193
Cdd:NF040978   814 QAVNSLIKAEINGSSQSVEVSFITGDISQ--LTSTIKTDDVSYTAGGKIKVSVT--LMDEQKNLVKGM-ASLLAGS 884
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
70-146 4.74e-04

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 37.64  E-value: 4.74e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1440416638  70 ITAKVTDANGNPLANQTVTfnVAEGATITPHEVQTGADGNagATVTSLKAGTYAVTAEVNGKGTSKNTTFVADKDSA 146
Cdd:pfam13620   2 ISGTVTDPSGAPVPGATVT--VTNTDTGTVRTTTTDADGR--YRFPGLPPGTYTVTVSAPGFKTATRTGVTVTAGQT 74
Ve_IatC_Nterm NF040978
inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve ...
 23-184 7.91e-04

inverse autotransporter adhesin IatC N-terminal domain; The inverse autotransporter (type Ve secretion protein) IatC contains a central region that is variable in the number of repeats seen, and averages about 3000 amino acids in length. This HMM describes a mostly non-repetitive region N-teminal to the architectural differences from different repeat counts are seen. IatC can contribute to biofilm formation.


Pssm-ID: 468908 [Multi-domain]  Cd Length: 1065  Bit Score: 39.79  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   23 YTVTAKVNDSEA----KKDAHFVADSDTAEITDGNLSVGTGAT-ANGKDINAITAKVTDANGNPLANQTVTFNVAEGATI 97
Cdd:NF040978   506 YPIAVTAEDSKGnfsrREESMVVVEKPTLSLADSTLSVDLQILlADGKSISTLTYTARDSSGKPIPGMTLKTHAKGLQDF 585

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   98 TPHEVQTGADGNAGATVTSLK-AGTYAVTAEVNGKGTSKNTTFVAD-KDSAGIADGDLAVGDNNAVADGKSTDSVTAKvt 175
Cdd:NF040978   586 ALSEWKDNGNGTYTQIVTAGKtSGALSLMPQFNGDDIAKTPALIAIvANMASRADSMIETDQDNYVAGKPIGVKVTLK-- 663


                   ....*....
gi 1440416638  176 DANGNPVSG 184
Cdd:NF040978   664 DDNGNGVTG 672
Invasin_D3 pfam09134
Invasin, domain 3; Members of this family adopt a structure consisting of an ...
 58-130 2.16e-03

Invasin, domain 3; Members of this family adopt a structure consisting of an immunoglobulin-like beta-sandwich, with seven strands in two beta-sheets, arranged in a Greek-key topology. It forms part of the extracellular region of the protein, which can be expressed as a soluble protein (Inv497) that binds integrins and promotes subsequent uptake by cells when attached to bacteria.


Pssm-ID: 430426 [Multi-domain]  Cd Length: 98  Bit Score: 36.14  E-value: 2.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1440416638  58 TGATANGKDINAITAKVTDANGNPL--ANQTVTFNVAEGatiTPHEVQTGADGNAGATVTSL-KAGTYAVTAEVNG 130
Cdd:pfam09134  12 ASIVADGVSTSTLTVTLKDANGNPLtvGGATVTFSTTAG---TLSAVTDNGDGTYTATLTSGtTAGTATVTFTVNG 84
Glyco_hydro2_C5 pfam18565
Glycoside hydrolase family 2 C-terminal domain 5; Domain 5 is found in dimeric ...
 62-130 8.32e-03

Glycoside hydrolase family 2 C-terminal domain 5; Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.


Pssm-ID: 436582  Cd Length: 103  Bit Score: 34.74  E-value: 8.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638  62 ANGKDINAITAKVTDANGN--PLANQTVTFNVAEGATI--------TPHEVQTGA-----DGNAGATVTSL-KAGTYAVT 125
Cdd:pfam18565  12 ADGKDLAFVTVEVVDKNGNlvPNADNLVTFSVEGPGELvgvdngdpTSLESFQSNerkafNGKALAIVRSTgEAGTITLT 91


                  ....*
gi 1440416638 126 AEVNG 130
Cdd:pfam18565  92 ASAEG 96
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 54-210 9.23e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 36.56  E-value: 9.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1440416638   54 LSVGTGATANGKDInaITAKVTDANGNPLANQTVTFNVAEGATITPHEVQTGADGNagaTVTSLKAGTYAVTAEVNGKGT 133
Cdd:NF038112  1258 LVVSDGTKTSAPDT--VTVLVRNVNRAPVAVAGAPATVDERSTVTLDGSGTDADGD---ALTYAWTQTSGPAVTLTGATT 1332

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1440416638  134 SKnTTFVADKDSAGIA-DGDLAVGDNNAVAdgksTDSVTAKVTDANGNPVSGVEVSFLAGNDATVVTETVTTGADGMA 210
Cdd:NF038112  1333 AT-ATFTAPEVTADTQlTFTLTVSDGTASA----TDTVTVTVRNVNRAPVANAGADQTVDERSTVTLSGSATDPDGDA 1405
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH