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Conserved domains on  [gi|1439042728|gb|AXI62729|]
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hypothetical protein DLD99_20350 [Pseudomonas kribbensis]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10008642)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  3.40.50.150
EC:  2.1.1.-
Gene Ontology:  GO:1904047|GO:0008168|GO:0032259|GO:0008757
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
1-86 5.54e-31

Predicted SAM-depedendent methyltransferase [General function prediction only];


:

Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 113.42  E-value: 5.54e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   1 MVVLDIGCGRKKITGAIGIDFSAMSDADITLDLNKeRLPFEDSSVDFIFSSHTLEHLTIEGFLHVMEECYRVLKPAGQLK 80
Cdd:COG4627     4 PLKLNIGCGPKRLPGWLNVDIVPAPGVDIVGDLTD-PLPFPDNSVDAIYSSHVLEHLDYEEAPLALKECYRVLKPGGILR 82


                  ....*.
gi 1439042728  81 IVVPYF 86
Cdd:COG4627    83 IVVPDL 88
 
Name Accession Description Interval E-value
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
1-86 5.54e-31

Predicted SAM-depedendent methyltransferase [General function prediction only];


Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 113.42  E-value: 5.54e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   1 MVVLDIGCGRKKITGAIGIDFSAMSDADITLDLNKeRLPFEDSSVDFIFSSHTLEHLTIEGFLHVMEECYRVLKPAGQLK 80
Cdd:COG4627     4 PLKLNIGCGPKRLPGWLNVDIVPAPGVDIVGDLTD-PLPFPDNSVDAIYSSHVLEHLDYEEAPLALKECYRVLKPGGILR 82


                  ....*.
gi 1439042728  81 IVVPYF 86
Cdd:COG4627    83 IVVPDL 88
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 3-77 1.13e-15

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 70.67  E-value: 1.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTGAIGIDFSAMSDADIT-LDLNK------------------------ERLPFEDSSVDFIFSSHTLEHL 57
Cdd:pfam13649   1 VLDLGCG----TGRLTLALARRGGARVTgVDLSPemlerareraaeaglnvefvqgdaEDLPFPDGSFDLVVSSGVLHHL 76

                          90       100
                  ....*....|....*....|
gi 1439042728  58 TIEGFLHVMEECYRVLKPAG 77
Cdd:pfam13649  77 PDPDLEAALREIARVLKPGG 96
PRK08317 PRK08317
hypothetical protein; Provisional
 3-79 1.27e-07

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 51.48  E-value: 1.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGR-------KKITG----AIGIDFSAMSdaditLDLNKER-----------------LPFEDSSVDFIFSSHTL 54
Cdd:PRK08317   23 VLDVGCGPgndarelARRVGpegrVVGIDRSEAM-----LALAKERaaglgpnvefvrgdadgLPFPDGSFDAVRSDRVL 97

                          90       100
                  ....*....|....*....|....*.
gi 1439042728  55 EHLT-IEGFLHvmeECYRVLKPAGQL 79
Cdd:PRK08317   98 QHLEdPARALA---EIARVLRPGGRV 120
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 3-79 9.86e-06

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 45.74  E-value: 9.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCG--------RKKITGA--IGIDFSA-M--------SDADITLDLNKERLPFEDSSVDFIFSSHTLEHLtiEGFL 63
Cdd:TIGR02072  38 VLDIGCGtgyltralLKRFPQAefIALDISAgMlaqaktklSENVQFICGDAEKLPLEDSSFDLIVSNLALQWC--DDLS 115

                          90
                  ....*....|....*.
gi 1439042728  64 HVMEECYRVLKPAGQL 79
Cdd:TIGR02072 116 QALSELARVLKPGGLL 131
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 3-86 3.98e-05

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 42.03  E-value: 3.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTGAIGIDFSAMSDADIT-LDLNKERL--------------------------PFEDSSVDFIFSSHTLE 55
Cdd:cd02440     2 VLDLGCG----TGALALALASGPGARVTgVDISPVALelarkaaaalladnvevlkgdaeelpPEADESFDVIISDPPLH 77

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1439042728  56 HLtIEGFLHVMEECYRVLKPAGQLKIVVPYF 86
Cdd:cd02440    78 HL-VEDLARFLEEARRLLKPGGVLVLTLVLA 107
 
Name Accession Description Interval E-value
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
1-86 5.54e-31

Predicted SAM-depedendent methyltransferase [General function prediction only];


Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 113.42  E-value: 5.54e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   1 MVVLDIGCGRKKITGAIGIDFSAMSDADITLDLNKeRLPFEDSSVDFIFSSHTLEHLTIEGFLHVMEECYRVLKPAGQLK 80
Cdd:COG4627     4 PLKLNIGCGPKRLPGWLNVDIVPAPGVDIVGDLTD-PLPFPDNSVDAIYSSHVLEHLDYEEAPLALKECYRVLKPGGILR 82


                  ....*.
gi 1439042728  81 IVVPYF 86
Cdd:COG4627    83 IVVPDL 88
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 3-77 1.13e-15

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 70.67  E-value: 1.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTGAIGIDFSAMSDADIT-LDLNK------------------------ERLPFEDSSVDFIFSSHTLEHL 57
Cdd:pfam13649   1 VLDLGCG----TGRLTLALARRGGARVTgVDLSPemlerareraaeaglnvefvqgdaEDLPFPDGSFDLVVSSGVLHHL 76

                          90       100
                  ....*....|....*....|
gi 1439042728  58 TIEGFLHVMEECYRVLKPAG 77
Cdd:pfam13649  77 PDPDLEAALREIARVLKPGG 96
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 1-94 1.93e-13

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 66.17  E-value: 1.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   1 MVVLDIGCGrkkiTGA------------IGIDFSA---------MSDADITLDL---NKERLPFEDSSVDFIFSSHTLEH 56
Cdd:COG2226    24 ARVLDLGCG----TGRlalalaergarvTGVDISPemlelarerAAEAGLNVEFvvgDAEDLPFPDGSFDLVISSFVLHH 99

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1439042728  57 LtiEGFLHVMEECYRVLKPAGQLKIVVPYFTTTANLAN 94
Cdd:COG2226   100 L--PDPERALAEIARVLKPGGRLVVVDFSPPDLAELEE 135
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 4-79 1.31e-12

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 62.30  E-value: 1.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   4 LDIGCGRKKITGA--------IGIDFSAMSDADITLDLNK----------ERLPFEDSSVDFIFSSHTLEHLT-IEGFLh 64
Cdd:pfam08241   1 LDVGCGTGLLTELlarlgarvTGVDISPEMLELAREKAPRegltfvvgdaEDLPFPDNSFDLVLSSEVLHHVEdPERAL- 79

                          90
                  ....*....|....*
gi 1439042728  65 vmEECYRVLKPAGQL 79
Cdd:pfam08241  80 --REIARVLKPGGIL 92
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 3-84 3.90e-11

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 59.26  E-value: 3.90e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTG------------AIGIDFSA---------MSDADITL---DLnkERLPFEDSSVDFIFSSHTLEHLt 58
Cdd:COG2227    28 VLDVGCG----TGrlalalarrgadVTGVDISPealeiarerAAELNVDFvqgDL--EDLPLEDGSFDLVICSEVLEHL- 100

                          90       100
                  ....*....|....*....|....*.
gi 1439042728  59 iEGFLHVMEECYRVLKPAGQLKIVVP 84
Cdd:COG2227   101 -PDPAALLRELARLLKPGGLLLLSTP 125
PRK08317 PRK08317
hypothetical protein; Provisional
 3-79 1.27e-07

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 51.48  E-value: 1.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGR-------KKITG----AIGIDFSAMSdaditLDLNKER-----------------LPFEDSSVDFIFSSHTL 54
Cdd:PRK08317   23 VLDVGCGPgndarelARRVGpegrVVGIDRSEAM-----LALAKERaaglgpnvefvrgdadgLPFPDGSFDAVRSDRVL 97

                          90       100
                  ....*....|....*....|....*.
gi 1439042728  55 EHLT-IEGFLHvmeECYRVLKPAGQL 79
Cdd:PRK08317   98 QHLEdPARALA---EIARVLRPGGRV 120
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
3-79 4.20e-07

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 47.13  E-value: 4.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCG--------RKKITGA--IGIDFS-AMsdaditLDLNKERLP---FE---------DSSVDFIFSSHTLEHLti 59
Cdd:COG4106     5 VLDLGCGtgrltallAERFPGArvTGVDLSpEM------LARARARLPnvrFVvadlrdldpPEPFDLVVSNAALHWL-- 76

                          90       100
                  ....*....|....*....|
gi 1439042728  60 EGFLHVMEECYRVLKPAGQL 79
Cdd:COG4106    77 PDHAALLARLAAALAPGGVL 96
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 3-88 6.76e-06

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 45.68  E-value: 6.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGRKKITGA---------IGIDFS------AMSDAD---------ITLDLNkERLPFEDSSVDFIFSSHTLEHLT 58
Cdd:COG0500    30 VLDLGCGTGRNLLAlaarfggrvIGIDLSpeaialARARAAkaglgnvefLVADLA-ELDPLPAESFDLVVAFGVLHHLP 108

                          90       100       110
                  ....*....|....*....|....*....|
gi 1439042728  59 IEGFLHVMEECYRVLKPAGQLkIVVPYFTT 88
Cdd:COG0500   109 PEEREALLRELARALKPGGVL-LLSASDAA 137
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 3-79 9.86e-06

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 45.74  E-value: 9.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCG--------RKKITGA--IGIDFSA-M--------SDADITLDLNKERLPFEDSSVDFIFSSHTLEHLtiEGFL 63
Cdd:TIGR02072  38 VLDIGCGtgyltralLKRFPQAefIALDISAgMlaqaktklSENVQFICGDAEKLPLEDSSFDLIVSNLALQWC--DDLS 115

                          90
                  ....*....|....*.
gi 1439042728  64 HVMEECYRVLKPAGQL 79
Cdd:TIGR02072 116 QALSELARVLKPGGLL 131
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 1-84 2.49e-05

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 43.38  E-value: 2.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   1 MVVLDIGCGRkkitGAIGIDFSAMSDADIT-LDLNKE-------------------------RLPFEDSSVDFIFSSHTL 54
Cdd:COG2230    53 MRVLDIGCGW----GGLALYLARRYGVRVTgVTLSPEqleyareraaeagladrvevrladyRDLPADGQFDAIVSIGMF 128

                          90       100       110
                  ....*....|....*....|....*....|
gi 1439042728  55 EHLTIEGFLHVMEECYRVLKPAGQLKIVVP 84
Cdd:COG2230   129 EHVGPENYPAYFAKVARLLKPGGRLLLHTP 158
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 3-98 2.80e-05

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 44.18  E-value: 2.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCG--------------RKKITGaigIDFS----------AMSDADIT-LDLNKERLPFEDSSVDFIFSSHTLEHL 57
Cdd:TIGR01934  43 VLDVACGtgdlaielaksapdRGKVTG---VDFSsemlevakkkSELPLNIEfIQADAEALPFEDNSFDAVTIAFGLRNV 119

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1439042728  58 TieGFLHVMEECYRVLKPAGQLkiVVPYFTTTAN-LANPFHN 98
Cdd:TIGR01934 120 T--DIQKALREMYRVLKPGGRL--VILEFSKPANaLLKKFYK 157
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 3-86 3.98e-05

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 42.03  E-value: 3.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTGAIGIDFSAMSDADIT-LDLNKERL--------------------------PFEDSSVDFIFSSHTLE 55
Cdd:cd02440     2 VLDLGCG----TGALALALASGPGARVTgVDISPVALelarkaaaalladnvevlkgdaeelpPEADESFDVIISDPPLH 77

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1439042728  56 HLtIEGFLHVMEECYRVLKPAGQLKIVVPYF 86
Cdd:cd02440    78 HL-VEDLARFLEEARRLLKPGGVLVLTLVLA 107
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 3-81 5.15e-05

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 43.60  E-value: 5.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTG---------------AIGIDFS-AM------------SDADITLDL-NKERLPFEDSSVDFIfssht 53
Cdd:PRK00216   55 VLDLACG----TGdlaialakavgktgeVVGLDFSeGMlavgreklrdlgLSGNVEFVQgDAEALPFPDNSFDAV----- 125

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1439042728  54 lehlTIeGF--------LHVMEECYRVLKPAGQLKI 81
Cdd:PRK00216  126 ----TI-AFglrnvpdiDKALREMYRVLKPGGRLVI 156
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
3-79 1.93e-04

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 41.66  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGRKKITGAI-----------GIDFS----------AMSDADITLDL---NKERLPFEDSSVDFIFSSHTLEHLT 58
Cdd:pfam01209  46 FLDVAGGTGDWTFGLsdsagssgkvvGLDINenmlkegekkAKEEGKYNIEFlqgNAEELPFEDDSFDIVTISFGLRNFP 125

                          90       100
                  ....*....|....*....|.
gi 1439042728  59 ieGFLHVMEECYRVLKPAGQL 79
Cdd:pfam01209 126 --DYLKVLKEAFRVLKPGGRV 144
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 1-123 6.84e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 39.33  E-value: 6.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   1 MVVLDIGCG--------RKKITGAIGIDFSAMSDADITLDLNKERLPFEDSSV-----DFIFSSHTLEHltIEGFLHVME 67
Cdd:pfam13489  24 GRVLDFGCGtgiflrllRAQGFSVTGVDPSPIAIERALLNVRFDQFDEQEAAVpagkfDVIVAREVLEH--VPDPPALLR 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1439042728  68 ECYRVLKPAGQLKIVVPyfTTTANLANPFHNNNICFNEHT-FRFFSSDSETDAMAKH 123
Cdd:pfam13489 102 QIAALLKPGGLLLLSTP--LASDEADRLLLEWPYLRPRNGhISLFSARSLKRLLEEA 156
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 4-79 7.27e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 38.12  E-value: 7.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   4 LDIGCG--------RKKITGA--IGIDFSAMSDADI-------------TLDLNKERLPFEDS-SVDFIFSSHTLEHL-T 58
Cdd:pfam08242   1 LEIGCGtgtllralLEALPGLeyTGLDISPAALEAArerlaalgllnavRVELFQLDLGELDPgSFDVVVASNVLHHLaD 80

                          90       100
                  ....*....|....*....|.
gi 1439042728  59 IEGFLhvmEECYRVLKPAGQL 79
Cdd:pfam08242  81 PRAVL---RNIRRLLKPGGVL 98
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 27-84 1.06e-03

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 39.16  E-value: 1.06e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1439042728  27 ADITldlnkeRLPFEDSSVDFIF-----------SSHTLEHLtIEGFLhvmEECYRVLKPAGQLKIVVP 84
Cdd:COG1041    81 GDAR------DLPLADESVDAIVtdppygrsskiSGEELLEL-YEKAL---EEAARVLKPGGRVVIVTP 139
PTZ00098 PTZ00098
phosphoethanolamine N-methyltransferase; Provisional
 6-81 2.52e-03

phosphoethanolamine N-methyltransferase; Provisional


Pssm-ID: 173391 [Multi-domain]  Cd Length: 263  Bit Score: 38.80  E-value: 2.52e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1439042728   6 IGCGRKKITGAIGIDFSAMsdaDItldLNKErlpFEDSSVDFIFSSHTLEHLTIEGFLHVMEECYRVLKPAGQLKI 81
Cdd:PTZ00098   88 VNIAKLRNSDKNKIEFEAN---DI---LKKD---FPENTFDMIYSRDAILHLSYADKKKLFEKCYKWLKPNGILLI 154
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
3-77 2.78e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 37.67  E-value: 2.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439042728   3 VLDIGCGrkkiTGA------------IGIDFSA-M------SDADITL---DLNkeRLPFEDSSVDFIFSSHTLEHLtiE 60
Cdd:COG4976    50 VLDLGCG----TGLlgealrprgyrlTGVDLSEeMlakareKGVYDRLlvaDLA--DLAEPDGRFDLIVAADVLTYL--G 121

                          90
                  ....*....|....*..
gi 1439042728  61 GFLHVMEECYRVLKPAG 77
Cdd:COG4976   122 DLAAVFAGVARALKPGG 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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