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Conserved domains on  [gi|14250424|gb|AAH08647|]
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TTC5 protein, partial [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11421408)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC5_OB pfam16669
Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the ...
 317-428 9.28e-58

Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the C-terminus of Tetratricopeptide repeat protein 5 and is required for effective p53 response.


:

Pssm-ID: 465225  Cd Length: 115  Bit Score: 185.51  E-value: 9.28e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424   317 TLELKPLSTLQPGVNSGAVILGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNIVQSWGVLIGDSVAIPEPNLRLHRIQ 396
Cdd:pfam16669   1 KLKRATLDDLKEGLNKGKVVLGKVVGSITHEEPVPLTFVLVDSEGTCFVVTVYNLAQGKGVKIGDSVAIPEPYLRFIDFS 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 14250424   397 HKGKDYSFSSVRVETPLLLVVNGKPQGSSSQA 428
Cdd:pfam16669  81 WKGKHFQFKSIRVDTPLQLLVNGKKLGPDSQA 112
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-273 1.40e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.12  E-value: 1.40e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  67 AQVLMLTGKALNVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-RNKVSLQNLSMVL 145
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYE-EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 146 RQL-RTDtedehshhvmDSVRQAKLAVQMDVHDGRSWYILGNSYLSLyfstGQNpkisQQALSAYAQAEKVDrkaSSNPD 224
Cdd:COG0457  87 QALgRYE----------EALEDYDKALELDPDDAEALYNLGLALLEL----GRY----DEAIEAYERALELD---PDDAD 145

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 14250424 225 LHLNRATLHKYEESYGEALEGFSRAAALDPAWPEPRQREQQLLEFLDRL 273
Cdd:COG0457 146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194
 
Name Accession Description Interval E-value
TTC5_OB pfam16669
Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the ...
 317-428 9.28e-58

Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the C-terminus of Tetratricopeptide repeat protein 5 and is required for effective p53 response.


Pssm-ID: 465225  Cd Length: 115  Bit Score: 185.51  E-value: 9.28e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424   317 TLELKPLSTLQPGVNSGAVILGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNIVQSWGVLIGDSVAIPEPNLRLHRIQ 396
Cdd:pfam16669   1 KLKRATLDDLKEGLNKGKVVLGKVVGSITHEEPVPLTFVLVDSEGTCFVVTVYNLAQGKGVKIGDSVAIPEPYLRFIDFS 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 14250424   397 HKGKDYSFSSVRVETPLLLVVNGKPQGSSSQA 428
Cdd:pfam16669  81 WKGKHFQFKSIRVDTPLQLLVNGKKLGPDSQA 112
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-273 1.40e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.12  E-value: 1.40e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  67 AQVLMLTGKALNVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-RNKVSLQNLSMVL 145
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYE-EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 146 RQL-RTDtedehshhvmDSVRQAKLAVQMDVHDGRSWYILGNSYLSLyfstGQNpkisQQALSAYAQAEKVDrkaSSNPD 224
Cdd:COG0457  87 QALgRYE----------EALEDYDKALELDPDDAEALYNLGLALLEL----GRY----DEAIEAYERALELD---PDDAD 145

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 14250424 225 LHLNRATLHKYEESYGEALEGFSRAAALDPAWPEPRQREQQLLEFLDRL 273
Cdd:COG0457 146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194
TPR_11 pfam13414
TPR repeat;
85-116 1.27e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 1.27e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 14250424    85 PKAEELLSKAVKLEPELVEAWNQLGEVYWKKG 116
Cdd:pfam13414  11 EEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 66-132 1.47e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 1.47e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 14250424  66 KAQVLMltgkalnVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC 132
Cdd:cd24142   6 KAEELL-------DQGNFE-LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELD 64
 
Name Accession Description Interval E-value
TTC5_OB pfam16669
Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the ...
 317-428 9.28e-58

Tetratricopeptide repeat protein 5 OB fold domain; This OB fold domain is located at the C-terminus of Tetratricopeptide repeat protein 5 and is required for effective p53 response.


Pssm-ID: 465225  Cd Length: 115  Bit Score: 185.51  E-value: 9.28e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424   317 TLELKPLSTLQPGVNSGAVILGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNIVQSWGVLIGDSVAIPEPNLRLHRIQ 396
Cdd:pfam16669   1 KLKRATLDDLKEGLNKGKVVLGKVVGSITHEEPVPLTFVLVDSEGTCFVVTVYNLAQGKGVKIGDSVAIPEPYLRFIDFS 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 14250424   397 HKGKDYSFSSVRVETPLLLVVNGKPQGSSSQA 428
Cdd:pfam16669  81 WKGKHFQFKSIRVDTPLQLLVNGKKLGPDSQA 112
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-273 1.40e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.12  E-value: 1.40e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  67 AQVLMLTGKALNVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-RNKVSLQNLSMVL 145
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYE-EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLAL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 146 RQL-RTDtedehshhvmDSVRQAKLAVQMDVHDGRSWYILGNSYLSLyfstGQNpkisQQALSAYAQAEKVDrkaSSNPD 224
Cdd:COG0457  87 QALgRYE----------EALEDYDKALELDPDDAEALYNLGLALLEL----GRY----DEAIEAYERALELD---PDDAD 145

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 14250424 225 LHLNRATLHKYEESYGEALEGFSRAAALDPAWPEPRQREQQLLEFLDRL 273
Cdd:COG0457 146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
95-272 7.30e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.19  E-value: 7.30e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  95 VKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNK-VSLQNLSMVLRQLRtdtedehshHVMDSVRQAKLAVQM 173
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDaEALYNLGLAYLRLG---------RYEEALADYEQALEL 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 174 DVHDGRSWYILGNSYLSLyfstGQNpkisQQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGEALEGFSRAAALD 253
Cdd:COG0457  72 DPDDAEALNNLGLALQAL----GRY----EEALEDYDKALELD---PDDAEALYNLGLALLELGRYDEAIEAYERALELD 140

                       170
                ....*....|....*....
gi 14250424 254 PAWPEPRQREQQLLEFLDR 272
Cdd:COG0457 141 PDDADALYNLGIALEKLGR 159
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 86-278 1.38e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.75  E-value: 1.38e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  86 KAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL-THCRNKVSLQNLSMVLRQLRtDTEdehshhvmDSV 164
Cdd:COG2956  60 RAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLeLDPDDAEALRLLAEIYEQEG-DWE--------KAI 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 165 RQAKLAVQMDVHDGRSWYILGNsylsLYFSTGQNpkisQQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEALE 244
Cdd:COG2956 131 EVLERLLKLGPENAHAYCELAE----LYLEQGDY----DEAIEALEKALKLDPD---CARALLLLAELYLEQGDYEEAIA 199

                       170       180       190
                ....*....|....*....|....*....|....
gi 14250424 245 GFSRAAALDPAWPEPRQREQQLLEFLDRLTSLLE 278
Cdd:COG2956 200 ALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 64-254 5.76e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 5.76e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  64 QGKAQVLMLTGKALNVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAhtcfsgalthcrnkvslqnlsm 143
Cdd:COG4783   1 AACAEALYALAQALLLAGDYD-EAEALLEKALELDPDNPEAFALLGEILLQLGDLDEA---------------------- 57

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 144 vLRQLRTdtedehshhvmdsvrqaklAVQMDVHDGRSWYILGNsylsLYFSTGQNpkisQQALSAYAQAEKVDrkaSSNP 223
Cdd:COG4783  58 -IVLLHE-------------------ALELDPDEPEARLNLGL----ALLKAGDY----DEALALLEKALKLD---PEHP 106

                       170       180       190
                ....*....|....*....|....*....|.
gi 14250424 224 DLHLNRATLHKYEESYGEALEGFSRAAALDP 254
Cdd:COG4783 107 EAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 67-266 2.67e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 2.67e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  67 AQVLMLTGKALNVTPDYsPKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVS-LQNLSMVL 145
Cdd:COG3914 112 AEALFNLGNLLLALGRL-EEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEaLNNLGNAL 190

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 146 RQLrtdtedehsHHVMDSVRQAKLAVQMDVHDGRSWYilgnSYLSLYFSTGQNPKIsqQALSAYAQAEKVDRKASSNPDL 225
Cdd:COG3914 191 QDL---------GRLEEAIAAYRRALELDPDNADAHS----NLLFALRQACDWEVY--DRFEELLAALARGPSELSPFAL 255

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 14250424 226 H----LNRATLHKYEESYGEALEgfSRAAALDPAWPEPRQREQQL 266
Cdd:COG3914 256 LylpdDDPAELLALARAWAQLVA--AAAAPELPPPPNPRDPDRKL 298
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 164-260 4.45e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 4.45e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 164 VRQAKLAVQMDVHDGRSWYILGNSYLSLyfstgQNPkisQQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEAL 243
Cdd:COG4235   3 IARLRQALAANPNDAEGWLLLGRAYLRL-----GRY---DEALAAYEKALRLDPD---NADALLDLAEALLAAGDTEEAE 71

                        90
                ....*....|....*..
gi 14250424 244 EGFSRAAALDPAWPEPR 260
Cdd:COG4235  72 ELLERALALDPDNPEAL 88
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 86-266 1.85e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 1.85e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  86 KAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALthcrnkvslqnlsmvlrqlrtdtedehshhvmdsvr 165
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL------------------------------------ 44

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 166 qaklavQMDVHDGRSWYILGNsylsLYFSTGQNPkisqQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGEALEG 245
Cdd:COG4235  45 ------RLDPDNADALLDLAE----ALLAAGDTE----EAEELLERALALD---PDNPEALYLLGLAAFQQGDYAEAIAA 107

                       170       180
                ....*....|....*....|.
gi 14250424 246 FSRAAALDPAWPEPRQREQQL 266
Cdd:COG4235 108 WQKLLALLPADAPARLLEASI 128
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 86-148 2.77e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 2.77e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 14250424  86 KAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC-RNKVSLQNLSMVLRQL 148
Cdd:COG5010  72 ESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSpDNPNAYSNLAALLLSL 135
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 65-129 4.19e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 4.19e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 14250424  65 GKAQVLMLTGKalnvtpdySPKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL 129
Cdd:COG4235  56 DLAEALLAAGD--------TEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
86-149 4.97e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 4.97e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 14250424  86 KAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTcFSGALTHCRNKV-SLQNLSMVLRQLR 149
Cdd:COG3063  10 EAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAeALLNLAELLLELG 73
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 170-273 1.12e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 1.12e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 170 AVQMDVHDGRSWYILGNsylsLYFSTGQNpkisQQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEALEGFSRA 249
Cdd:COG4783  30 ALELDPDNPEAFALLGE----ILLQLGDL----DEAIVLLHEALELDPD---EPEARLNLGLALLKAGDYDEALALLEKA 98

                        90       100
                ....*....|....*....|....
gi 14250424 250 AALDPAWPEPRQREQQLLEFLDRL 273
Cdd:COG4783  99 LKLDPEHPEAYLRLARAYRALGRP 122
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
165-254 1.31e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 1.31e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 165 RQAKLAVQMDVHDGRSWYILGNSYLSLyfstGQnpkiSQQALSAYAQAEKVDrkaSSNPDLHLNRATLHKYEESYGEALE 244
Cdd:COG4785  60 AERIDRALALPDLAQLYYERGVAYDSL----GD----YDLAIADFDQALELD---PDLAEAYNNRGLAYLLLGDYDAALE 128

                        90
                ....*....|
gi 14250424 245 GFSRAAALDP 254
Cdd:COG4785 129 DFDRALELDP 138
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 67-129 2.08e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 2.08e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 14250424  67 AQVLMLTGKAlnvtpdysPKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL 129
Cdd:COG5010  95 ALLYSRSGDK--------DEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 138-273 2.40e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 2.40e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 138 LQNLSMVLRQLRTDTEDEHSHHVMDSVRQAKLAVQMDVHDGRSWYILGNSYLSLYFSTGQNpkisQQALSAYAQAEKVDR 217
Cdd:COG5010  10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDF----EESLALLEQALQLDP 85

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 14250424 218 KassNPDLHLNRATLHKYEESYGEALEGFSRAAALDPAWPEPRQREQQLLEFLDRL 273
Cdd:COG5010  86 N---NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
28-129 3.79e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 3.79e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  28 CYFETHSVEDAgrkqqdvRKEMEKTLQQMEEVVGSVQGKAQVLMLTGKAlnvtpdysPKAEELlSKAVKLEPELVEAWNQ 107
Cdd:COG3063   1 LYLKLGDLEEA-------EEYYEKALELDPDNADALNNLGLLLLEQGRY--------DEAIAL-EKALKLDPNNAEALLN 64

                        90       100
                ....*....|....*....|..
gi 14250424 108 LGEVYWKKGDVAAAHTCFSGAL 129
Cdd:COG3063  65 LAELLLELGDYDEALAYLERAL 86
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 203-273 6.08e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.29  E-value: 6.08e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 14250424 203 QQALSAYAQAEKVDRKA----SSNPDLHLNRATLHKYEESYGEALEGFSRAAALDPAWPEPRQREQQLLEFLDRL 273
Cdd:COG3914  88 LQALGRYEEALALYRRAlalnPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRL 162
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
67-129 1.24e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.28  E-value: 1.24e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 14250424  67 AQVLMLTGKALNVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGAL 129
Cdd:COG4785  73 AQLYYERGVAYDSLGDYD-LAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
TPR_11 pfam13414
TPR repeat;
85-116 1.27e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 1.27e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 14250424    85 PKAEELLSKAVKLEPELVEAWNQLGEVYWKKG 116
Cdd:pfam13414  11 EEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 66-132 1.47e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 1.47e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 14250424  66 KAQVLMltgkalnVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHC 132
Cdd:cd24142   6 KAEELL-------DQGNFE-LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELD 64
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 170-254 1.67e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.17  E-value: 1.67e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 170 AVQMDVHDGRSWYILGNSYLSLyfstGQNpkisQQALSAYAQAEKVDRkasSNPDLHLNRATLHKYEESYGEALEGFSRA 249
Cdd:COG5010  80 ALQLDPNNPELYYNLALLYSRS----GDK----DEAKEYYEKALALSP---DNPNAYSNLAALLLSLGQDDEAKAALQRA 148


                ....*
gi 14250424 250 AALDP 254
Cdd:COG5010 149 LGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 46-129 1.83e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 1.83e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  46 RKEMEKTLQQMEEVVGSVQGKAQVLMLTGKALNVTPDYSpKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCF 125
Cdd:COG4783  51 LGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD-EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAAL 129


                ....
gi 14250424 126 SGAL 129
Cdd:COG4783 130 EKAL 133
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 11-153 2.38e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 39.71  E-value: 2.38e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424  11 ILQKLQELVDQLYSFR----DCYFETHSVEDAgrkqqdvRKEMEKTLQQMEEVVGSVQGKAQVLMLTGKAlnvtpdysPK 86
Cdd:COG2956 132 VLERLLKLGPENAHAYcelaELYLEQGDYDEA-------IEALEKALKLDPDCARALLLLAELYLEQGDY--------EE 196

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 14250424  87 AEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQLRTDTE 153
Cdd:COG2956 197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEA 263
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
191-273 2.59e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 2.59e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14250424 191 LYFSTGQNpkisQQALSAYAQAEKVDRKassNPDLHLNRATLHKYEESYGEALEgFSRAAALDPAWPEPRQREQQLLEFL 270
Cdd:COG3063   1 LYLKLGDL----EEAEEYYEKALELDPD---NADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72


                ...
gi 14250424 271 DRL 273
Cdd:COG3063  73 GDY 75
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 86-134 3.32e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.51  E-value: 3.32e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 14250424  86 KAEELLSKAVKLEPElVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRN 134
Cdd:COG3071 276 KAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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