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Conserved domains on  [gi|1421400534|gb|AXB29254|]
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beta-galactosidase [Faecalibacterium prausnitzii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bgal_small_N super family cl46900
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 15-981 0e+00

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


The actual alignment was detected with superfamily member PRK10340:

Pssm-ID: 481240 [Multi-domain]  Cd Length: 1021  Bit Score: 644.81  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   15 PEIFQQNRLPFHAHFADQTSPELSLTV---------SLDGEWNFRYAEN--------LTAPFTDWDTLTVPGFIQMQSlq 77
Cdd:PRK10340     7 IQLTHENRLAPRAYFFSYDSVAQARTFaretsslflLLSGQWNFHFFDHplyvpeafTSELMSDWGHITVPAMWQMEG-- 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   78 kpgqpYGTPHYVNTQYPWdgheKLHPGQIPQDyNPIGEYQRSFTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDT 155
Cdd:PRK10340    85 -----HGKLQYTDEGFPF----PIDVPFVPSD-NPTGAYQRTFTLSDGWQGkqTIIKFDGVETYFEVYVNGQYVGFSKGS 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  156 FTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQDFWRMSGLFRSVELFTKPEVHLEDVFVKQSFADDFSSAAVTfdck 235
Cdd:PRK10340   155 RLTAEFDISAMVKTGDNLLCVRVMQWADSTYLEDQDMWWLAGIFRDVYLVGKPLTHINDFTVRTDFDEDYCDATLS---- 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  236 vsgagtVSVVFNGQEQSAEVG--EPAEYDSGVVFGKGEVAPDVEEDVQDVSFTFAVTDPALWSAEQPNLYEAEIALLRE- 312
Cdd:PRK10340   231 ------CEVVLENLAASPVVTtlEYTLFDGERVVHSSAIDHLAIEKLTSASFAFTVEQPQQWSAESPYLYHLVMTLKDAn 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  313 GALVERTGLKVGLRKFELKDRQMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFL 392
Cdd:PRK10340   305 GNVLEVVPQRVGFRDIKVRDGLFWINNRYVKLHGVNRHDNDHRKGRAVGMDRVEKDIQLMKQHNINSVRTAHYPNDPRFY 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  393 QLCDEYGLYVIGETNLETHGTwqklgaDGSDEWTLPGARPEWRENVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWE 472
Cdd:PRK10340   385 ELCDIYGLFVMAETDVESHGF------ANVGDISRITDDPQWEKVYVDRIVRHIHAQKNHPSIIIWSLGNESGYGCNIRA 458

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  473 MSEYFRRTDPSRLVHYEGifwNREYPATsDMESQMYTPVADIKKFlAEHP-EKPFIMCEYSHAMGNSCGGITDYTEYAYE 551
Cdd:PRK10340   459 MYHAAKALDDTRLVHYEE---DRDAEVV-DVISTMYTRVELMNEF-GEYPhPKPRILCEYAHAMGNGPGGLTEYQNVFYK 533

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  552 EPLYQGGFIWEYMDHGIAVTDPDGKPCFAYGGDFGDRPTDREFCVDGLVLPDRRNTPKMDAVKAAYAPLKITLTDTEA-- 629
Cdd:PRK10340   534 HDCIQGHYVWEWCDHGIQAQDDNGNVWYKYGGDYGDYPNNYNFCIDGLIYPDQTPGPGLKEYKQVIAPVKIHALDLTRge 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  630 -VIENRNLFTDLNAYDLVFASSVNGKPERRAVLRA-DCAPGET--VHLLFP-FALPETGLacmTVTAIQRAAKPGIPAGY 704
Cdd:PRK10340   614 lKVENKLWFTNLDDYTLHAEVRAEGETLASGQIKLrDVAPNSEapLQITLPqLDAREAFL---NITVTKDSRTRYSEAGH 690

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  705 EAAFGQVWHNYAAARLTLPAP------QLVEMDCNIGVKGKGFEYIFGRGKG-LVSIRYNGVQLLDDTVRPNFWRAPTNN 777
Cdd:PRK10340   691 SIATYQFPLKENTAQPVPFAPnnarplTLEEDRLSCTVRGYNFAITFSKVSGkLTSWQVNGESLLTREPKINFFKPMIDN 770

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  778 D----EGCAEPFTFAFWKTaglyaRCDNLTAEAKDEFVIV-----------------RANYTL-PDGQtlpIDFAIDGAg 835
Cdd:PRK10340   771 HkqeyEGLWQPNHLQIMQE-----HLRDFAVEQSDGEVLIisrtviappvfdfgmrcTYIYRIaADGQ---VNVALSGE- 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  836 rcditmTWQGARTELPEFGLLFPLRRELTEVSYLGLGPRETTADRTAGGKMGAWSYNVRQDFaQNTPVyPQECGSRTDVY 915
Cdd:PRK10340   842 ------RYGDYPHMIPCIGFTMGINGEYDQVAYYGRGPGENYADSQQANLIDIYRSTVDAMF-ENYPF-PQNNGNRQHVR 913

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1421400534  916 SAAVT---GSGLNIgigFAGDSMTFSALPYTPHELENARHLYELPRDDNKTVVrcAAFQRGVGGDNSWG 981
Cdd:PRK10340   914 WTALTnrhGNGLLV---VPQRPINFSAWHYTQENIHAAQHTNELQKSDYITLN--LDHQLLGLGSNSWG 977
 
Name Accession Description Interval E-value
ebgA PRK10340
cryptic beta-D-galactosidase subunit alpha; Reviewed
 15-981 0e+00

cryptic beta-D-galactosidase subunit alpha; Reviewed


Pssm-ID: 236673 [Multi-domain]  Cd Length: 1021  Bit Score: 644.81  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   15 PEIFQQNRLPFHAHFADQTSPELSLTV---------SLDGEWNFRYAEN--------LTAPFTDWDTLTVPGFIQMQSlq 77
Cdd:PRK10340     7 IQLTHENRLAPRAYFFSYDSVAQARTFaretsslflLLSGQWNFHFFDHplyvpeafTSELMSDWGHITVPAMWQMEG-- 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   78 kpgqpYGTPHYVNTQYPWdgheKLHPGQIPQDyNPIGEYQRSFTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDT 155
Cdd:PRK10340    85 -----HGKLQYTDEGFPF----PIDVPFVPSD-NPTGAYQRTFTLSDGWQGkqTIIKFDGVETYFEVYVNGQYVGFSKGS 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  156 FTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQDFWRMSGLFRSVELFTKPEVHLEDVFVKQSFADDFSSAAVTfdck 235
Cdd:PRK10340   155 RLTAEFDISAMVKTGDNLLCVRVMQWADSTYLEDQDMWWLAGIFRDVYLVGKPLTHINDFTVRTDFDEDYCDATLS---- 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  236 vsgagtVSVVFNGQEQSAEVG--EPAEYDSGVVFGKGEVAPDVEEDVQDVSFTFAVTDPALWSAEQPNLYEAEIALLRE- 312
Cdd:PRK10340   231 ------CEVVLENLAASPVVTtlEYTLFDGERVVHSSAIDHLAIEKLTSASFAFTVEQPQQWSAESPYLYHLVMTLKDAn 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  313 GALVERTGLKVGLRKFELKDRQMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFL 392
Cdd:PRK10340   305 GNVLEVVPQRVGFRDIKVRDGLFWINNRYVKLHGVNRHDNDHRKGRAVGMDRVEKDIQLMKQHNINSVRTAHYPNDPRFY 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  393 QLCDEYGLYVIGETNLETHGTwqklgaDGSDEWTLPGARPEWRENVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWE 472
Cdd:PRK10340   385 ELCDIYGLFVMAETDVESHGF------ANVGDISRITDDPQWEKVYVDRIVRHIHAQKNHPSIIIWSLGNESGYGCNIRA 458

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  473 MSEYFRRTDPSRLVHYEGifwNREYPATsDMESQMYTPVADIKKFlAEHP-EKPFIMCEYSHAMGNSCGGITDYTEYAYE 551
Cdd:PRK10340   459 MYHAAKALDDTRLVHYEE---DRDAEVV-DVISTMYTRVELMNEF-GEYPhPKPRILCEYAHAMGNGPGGLTEYQNVFYK 533

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  552 EPLYQGGFIWEYMDHGIAVTDPDGKPCFAYGGDFGDRPTDREFCVDGLVLPDRRNTPKMDAVKAAYAPLKITLTDTEA-- 629
Cdd:PRK10340   534 HDCIQGHYVWEWCDHGIQAQDDNGNVWYKYGGDYGDYPNNYNFCIDGLIYPDQTPGPGLKEYKQVIAPVKIHALDLTRge 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  630 -VIENRNLFTDLNAYDLVFASSVNGKPERRAVLRA-DCAPGET--VHLLFP-FALPETGLacmTVTAIQRAAKPGIPAGY 704
Cdd:PRK10340   614 lKVENKLWFTNLDDYTLHAEVRAEGETLASGQIKLrDVAPNSEapLQITLPqLDAREAFL---NITVTKDSRTRYSEAGH 690

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  705 EAAFGQVWHNYAAARLTLPAP------QLVEMDCNIGVKGKGFEYIFGRGKG-LVSIRYNGVQLLDDTVRPNFWRAPTNN 777
Cdd:PRK10340   691 SIATYQFPLKENTAQPVPFAPnnarplTLEEDRLSCTVRGYNFAITFSKVSGkLTSWQVNGESLLTREPKINFFKPMIDN 770

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  778 D----EGCAEPFTFAFWKTaglyaRCDNLTAEAKDEFVIV-----------------RANYTL-PDGQtlpIDFAIDGAg 835
Cdd:PRK10340   771 HkqeyEGLWQPNHLQIMQE-----HLRDFAVEQSDGEVLIisrtviappvfdfgmrcTYIYRIaADGQ---VNVALSGE- 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  836 rcditmTWQGARTELPEFGLLFPLRRELTEVSYLGLGPRETTADRTAGGKMGAWSYNVRQDFaQNTPVyPQECGSRTDVY 915
Cdd:PRK10340   842 ------RYGDYPHMIPCIGFTMGINGEYDQVAYYGRGPGENYADSQQANLIDIYRSTVDAMF-ENYPF-PQNNGNRQHVR 913

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1421400534  916 SAAVT---GSGLNIgigFAGDSMTFSALPYTPHELENARHLYELPRDDNKTVVrcAAFQRGVGGDNSWG 981
Cdd:PRK10340   914 WTALTnrhGNGLLV---VPQRPINFSAWHYTQENIHAAQHTNELQKSDYITLN--LDHQLLGLGSNSWG 977
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
45-623 1.73e-158

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 481.95  E-value: 1.73e-158
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   45 GEWNFRYAENLTAP-----FTDWDTLTVPGFIQMQslqkpgqPYGTPHyvntqyPWDGHEKlhpgqipqDYNPIGEYQRS 119
Cdd:COG3250      1 GGWKFRLGDAPEGAkpdfdDSGWDPITVPGDWELD-------LYGLPD------PFVGPWY--------LYNGVGWYRRT 59

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  120 FTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDTFTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQDFWRMSG 197
Cdd:COG3250     60 FTVPASWKGkrVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLKPGENVLAVRVDNPSDGSYLEGQDWWRTSG 139

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  198 LFRSVELFTKPEVHLEDVFVKQSFADDfsSAAVTFDCKVSGAGTVSVVFNGQEQSAEVGEPAEYDSGVVFGKGEvapdve 277
Cdd:COG3250    140 IYRDVWLEATPKVHIEDVFVTPDLDDG--SATLTVEVELENESDAGVTVEVTLLDADGKVVATATAKVTLAAGE------ 211

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  278 edVQDVSFTFAVTDPALWSAEQPNLYEAEIALLREGALVERTGLKVGLRKFELKD-RQMLLNGQRIVFKGVNRHEWSCRT 356
Cdd:COG3250    212 --ENTVTLTLTVPNPKLWSPEDPNLYTLVVTLKDDGKVVDTVSTRFGFRTIEIDGdGGFLLNGKPVFLKGVNRHEDWPDD 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  357 GRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFLQLCDEYGLYVIGETNLETHGTWqklgadgsdewtlpGARPEWRE 436
Cdd:COG3250    290 GRAVTDEAMRRDLELMKEAGFNAVRTSHYPEDPEFYDLCDELGLLVWDEAPFEWHGML--------------GDDPEFLE 355

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  437 NVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWEMSEYFRRTDPSRLVhyegifwnreypatsdmesqmytpvadikk 516
Cdd:COG3250    356 AVEAELREMVRRDRNHPSIILWSGGNESGGGPNFAALYEWVKELDPTRPV------------------------------ 405

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  517 flaehpekpFIMCEYSHAMGNSCGG----------------ITDYTEYAYEEPLYQGGFIWEYMDHGIAVTDPDGKpcfa 580
Cdd:COG3250    406 ---------RFLSEYGHAMPNSLGGgyhqpsdfeeyqalqaLEEYWEAFRRRPRLAGGFIWQLNDYWPEPRDNDGN---- 472

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1421400534  581 yggdfgdrptdreFCVDGLVLP-DRRNTPKMDAVKAAYAPLKIT 623
Cdd:COG3250    473 -------------FCSWGLVDYyDRTPKPAYYEVKSAWQPVLVS 503
Glyco_hydro_2_C pfam02836
Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, ...
 328-622 1.50e-114

Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 397119 [Multi-domain]  Cd Length: 302  Bit Score: 354.83  E-value: 1.50e-114
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  328 FELKDRQMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFLQLCDEYGLYVIGETN 407
Cdd:pfam02836    1 VEVKDGLFLINGKPFYFRGVNRHEDHDRRGRGFDMDLMVKDIQLMKQNNINAVRTSHYPNHPEWYQLCDEYGIYVIDEAN 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  408 LETHGTWQKLGADGSDeWTLPGARPEWRENVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWEMSEYFRRTDPSRLVH 487
Cdd:pfam02836   81 LETHGLWQKFGEIEPS-YSELTDNPEWLPAHLERAEELVQRDKNHPSVIIWSLGNESGAGENIAAMYAATKSLDPTRPVH 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  488 YEGIFWNREYPA-TSDMESQMYTPV---ADIKKFL---AEHPEKPFIMCEYSHAMGNSCGGITDYTEYAYEEPLYQGGFI 560
Cdd:pfam02836  160 YEGVGIDPEVDDiILDIYSRMYEDYghpEVIEKYLedwYKKPQKPIIICEYGHAMGNSPGGLQEYQDLFYKYPEYQGGFI 239

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1421400534  561 WEYMDHGIAVTDP-DGKPCFAYGGDFGDRPTDREFCVDGLVLPDRRNTPKMDAVKAAYAPLKI 622
Cdd:pfam02836  240 WDWHDQGIQKRDPnVGGEWYWYGGDFGDRPSDYRFCGNGLFFADRTPKPALFELKKRYWPIKI 302
Bgal_small_N smart01038
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 737-1002 3.07e-68

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 214988 [Multi-domain]  Cd Length: 272  Bit Score: 229.39  E-value: 3.07e-68
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   737 KGKGFEYIFGRGKG-LVSIRYNGVQLLDDTVRPNFWRAPTNNDEGCAEPFTFAFWKTAGLYARCDNLTAEA--KDEFVIV 813
Cdd:smart01038    1 SGGGFSYTFDKATGaLTSWTYNGKELLLRGPKPNFWRAPTDNDRGNGPNAWAARWKAAGLDRLTTRVRSVEveQDSDVVV 80

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   814 RANYTLPDGQTLPID----FAIDGAGRCDITMTWQGAR---TELPEFGLLFPLRRELTEVSYLGLGPRETTADRTAGGKM 886
Cdd:smart01038   81 TVEYLLAAPSGWGFTvtvtYTIDGDGEVKVDVTFTPGGgalPDLPRIGLRFRLPDELEQVEWYGRGPGENYPDRKQSARL 160

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   887 GAWSYNVRQDFaqnTP-VYPQECGSRTDVYSAAVTGSGLNiGIGF-AGDSMTFSALPYTPHELENARHLYELPRDDNkTV 964
Cdd:smart01038  161 GRYSSTVDDLF---TPyVRPQENGNRTDVRWLTLTDDAGN-GLRVtADQPFSFSALPYSAEDLEEAKHPHELPPRDG-TV 235

                           250       260       270
                    ....*....|....*....|....*....|....*...
gi 1421400534   965 VRCAAFQRGVGGDNSWGAKPHADDCFAVEKgTSFRFTI 1002
Cdd:smart01038  236 LNLDAKQMGVGGDDSWGPGVLPEYRLPADE-YSFSFTL 272
 
Name Accession Description Interval E-value
ebgA PRK10340
cryptic beta-D-galactosidase subunit alpha; Reviewed
 15-981 0e+00

cryptic beta-D-galactosidase subunit alpha; Reviewed


Pssm-ID: 236673 [Multi-domain]  Cd Length: 1021  Bit Score: 644.81  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   15 PEIFQQNRLPFHAHFADQTSPELSLTV---------SLDGEWNFRYAEN--------LTAPFTDWDTLTVPGFIQMQSlq 77
Cdd:PRK10340     7 IQLTHENRLAPRAYFFSYDSVAQARTFaretsslflLLSGQWNFHFFDHplyvpeafTSELMSDWGHITVPAMWQMEG-- 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   78 kpgqpYGTPHYVNTQYPWdgheKLHPGQIPQDyNPIGEYQRSFTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDT 155
Cdd:PRK10340    85 -----HGKLQYTDEGFPF----PIDVPFVPSD-NPTGAYQRTFTLSDGWQGkqTIIKFDGVETYFEVYVNGQYVGFSKGS 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  156 FTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQDFWRMSGLFRSVELFTKPEVHLEDVFVKQSFADDFSSAAVTfdck 235
Cdd:PRK10340   155 RLTAEFDISAMVKTGDNLLCVRVMQWADSTYLEDQDMWWLAGIFRDVYLVGKPLTHINDFTVRTDFDEDYCDATLS---- 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  236 vsgagtVSVVFNGQEQSAEVG--EPAEYDSGVVFGKGEVAPDVEEDVQDVSFTFAVTDPALWSAEQPNLYEAEIALLRE- 312
Cdd:PRK10340   231 ------CEVVLENLAASPVVTtlEYTLFDGERVVHSSAIDHLAIEKLTSASFAFTVEQPQQWSAESPYLYHLVMTLKDAn 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  313 GALVERTGLKVGLRKFELKDRQMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFL 392
Cdd:PRK10340   305 GNVLEVVPQRVGFRDIKVRDGLFWINNRYVKLHGVNRHDNDHRKGRAVGMDRVEKDIQLMKQHNINSVRTAHYPNDPRFY 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  393 QLCDEYGLYVIGETNLETHGTwqklgaDGSDEWTLPGARPEWRENVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWE 472
Cdd:PRK10340   385 ELCDIYGLFVMAETDVESHGF------ANVGDISRITDDPQWEKVYVDRIVRHIHAQKNHPSIIIWSLGNESGYGCNIRA 458

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  473 MSEYFRRTDPSRLVHYEGifwNREYPATsDMESQMYTPVADIKKFlAEHP-EKPFIMCEYSHAMGNSCGGITDYTEYAYE 551
Cdd:PRK10340   459 MYHAAKALDDTRLVHYEE---DRDAEVV-DVISTMYTRVELMNEF-GEYPhPKPRILCEYAHAMGNGPGGLTEYQNVFYK 533

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  552 EPLYQGGFIWEYMDHGIAVTDPDGKPCFAYGGDFGDRPTDREFCVDGLVLPDRRNTPKMDAVKAAYAPLKITLTDTEA-- 629
Cdd:PRK10340   534 HDCIQGHYVWEWCDHGIQAQDDNGNVWYKYGGDYGDYPNNYNFCIDGLIYPDQTPGPGLKEYKQVIAPVKIHALDLTRge 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  630 -VIENRNLFTDLNAYDLVFASSVNGKPERRAVLRA-DCAPGET--VHLLFP-FALPETGLacmTVTAIQRAAKPGIPAGY 704
Cdd:PRK10340   614 lKVENKLWFTNLDDYTLHAEVRAEGETLASGQIKLrDVAPNSEapLQITLPqLDAREAFL---NITVTKDSRTRYSEAGH 690

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  705 EAAFGQVWHNYAAARLTLPAP------QLVEMDCNIGVKGKGFEYIFGRGKG-LVSIRYNGVQLLDDTVRPNFWRAPTNN 777
Cdd:PRK10340   691 SIATYQFPLKENTAQPVPFAPnnarplTLEEDRLSCTVRGYNFAITFSKVSGkLTSWQVNGESLLTREPKINFFKPMIDN 770

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  778 D----EGCAEPFTFAFWKTaglyaRCDNLTAEAKDEFVIV-----------------RANYTL-PDGQtlpIDFAIDGAg 835
Cdd:PRK10340   771 HkqeyEGLWQPNHLQIMQE-----HLRDFAVEQSDGEVLIisrtviappvfdfgmrcTYIYRIaADGQ---VNVALSGE- 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  836 rcditmTWQGARTELPEFGLLFPLRRELTEVSYLGLGPRETTADRTAGGKMGAWSYNVRQDFaQNTPVyPQECGSRTDVY 915
Cdd:PRK10340   842 ------RYGDYPHMIPCIGFTMGINGEYDQVAYYGRGPGENYADSQQANLIDIYRSTVDAMF-ENYPF-PQNNGNRQHVR 913

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1421400534  916 SAAVT---GSGLNIgigFAGDSMTFSALPYTPHELENARHLYELPRDDNKTVVrcAAFQRGVGGDNSWG 981
Cdd:PRK10340   914 WTALTnrhGNGLLV---VPQRPINFSAWHYTQENIHAAQHTNELQKSDYITLN--LDHQLLGLGSNSWG 977
lacZ PRK09525
beta-galactosidase;
1-980 0e+00

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 633.12  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534    1 MPLNHPITPALLA-----DPEIFQQNRLPFHAHFA----------DQTSPELsltVSLDGEWNFRYAEN--------LTA 57
Cdd:PRK09525     1 MTMIMDSLAQILArrdweNPGVTQLNRLPAHPPFAswrnseaardDRPSQQR---QSLNGEWRFSYFPApeavpeswLEC 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   58 PFTDWDTLTVPGFIQMQSlqkpgqpYGTPHYVNTQYPWDghekLHPGQIPQDyNPIGEYQRSFTLPESW-ASCYLRL--N 134
Cdd:PRK09525    78 DLPDADTIPVPSNWQLHG-------YDAPIYTNVTYPIP----VNPPFVPEE-NPTGCYSLTFTVDESWlQSGQTRIifD 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  135 GADSAAAVWCNGVYIGYTEDTFTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQDFWRMSGLFRSVELFTKPEVHLED 214
Cdd:PRK09525   146 GVNSAFHLWCNGRWVGYSQDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSD 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  215 VFVKQSFADDFSSAAVTFDCKVSGAGT----VSV-VFNGQEQSAEVGEPaeYDSGVVFGKGEVApdveedvQDVSFTFAV 289
Cdd:PRK09525   226 FHITTELDDDFRRAVLEVEAQVNGELRdelrVTVqLWDGETLVASGTAP--FGTEIIDERGAYA-------DRVTLRLNV 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  290 TDPALWSAEQPNLYEAEIALLR-EGALVERTGLKVGLRKFELKDRQMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWD 368
Cdd:PRK09525   297 ENPKLWSAETPNLYRAVVSLLDaDGTLIEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQD 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  369 VKNLKAHNVNAVRTSHYPDDPYFLQLCDEYGLYVIGETNLETHGT--WQKLGADgsdewtlpgarPEWRENVLARAEAML 446
Cdd:PRK09525   377 ILLMKQHNFNAVRCSHYPNHPLWYELCDRYGLYVVDEANIETHGMvpMNRLSDD-----------PRWLPAMSERVTRMV 445

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  447 ERDKNHPAILIWSCGNESHGGKTLWEMSEYFRRTDPSRLVHYEGIFWNReyPATsDMESQMYTPVAD-----------IK 515
Cdd:PRK09525   446 QRDRNHPSIIIWSLGNESGHGANHDALYRWIKSNDPSRPVQYEGGGADT--AAT-DIICPMYARVDEdqpfpavpkwsIK 522

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  516 KFLA---EHpeKPFIMCEYSHAMGNSCGGITDYTEyAYEE-PLYQGGFIWEYMDHGIAVTDPDGKPCFAYGGDFGDRPTD 591
Cdd:PRK09525   523 KWISlpgET--RPLILCEYAHAMGNSLGGFAKYWQ-AFRQyPRLQGGFIWDWVDQGLTKYDENGNPWWAYGGDFGDTPND 599

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  592 REFCVDGLVLPDRrnTPKMDAVKAAYA--PLKITLTDTEAV---IENRNLFTDLNAYDLVFASSVNGKPERRAVLRADCA 666
Cdd:PRK09525   600 RQFCMNGLVFPDR--TPHPALYEAKHAqqFFQFSLLSTTPLtieVTSEYLFRHSDNELLHWSVALDGKPLASGEVPLDLA 677

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  667 PGETVHLLFPfALPETGLAC---MTVTAIQRAAKPGIPAGYEAAfgqvWHNYA-AARLTLP-------APQLVEMDCNIG 735
Cdd:PRK09525   678 PQGSQRITLP-ELPQPESAGqlwLNVEVVQPNATAWSEAGHRSA----WQQWRlPEPLSLPlptashaAPQLTQDEQDFC 752

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  736 VKGKGFEYIFGRGKGLVSiRY--NGVQLLDDTVRPNFWRAPTNNDEGCAE-----PFT-FAFWKTAGLY---ARCDNLTA 804
Cdd:PRK09525   753 IELGNQRWQFNRQSGLLS-QWwvGGKEQLLTPLRDQFTRAPLDNDIGVSEatridPNAwVERWKAAGLYqleARLLQCDA 831

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  805 EAKDEFVIVRANYT-LPDGQTLPID---FAIDGAGRCDITMTWQGART--ELPEFGLLFPLRRELTEVSYLGLGPRETTA 878
Cdd:PRK09525   832 DTLADAVLITTEHAyQHQGKTLFISrktYRIDGQGEMTIDVDVEVASDlpPPARIGLTCQLAQVAERVSWLGLGPHENYP 911

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  879 DRTAGGKMGAWSYNVRqdfAQNTP-VYPQECGSRTDVysaavtgSGLNIGIGFAGDSMTFSALPYTPHELENARHLYELp 957
Cdd:PRK09525   912 DRLLAACFGRWDLPLS---DMHTPyIFPSENGLRCGT-------RELNYGRHQIRGDFHFNISRYSQQQLMETSHRHLL- 980

                         1050      1060
                   ....*....|....*....|...
gi 1421400534  958 RDDNKTVVRCAAFQRGVGGDNSW 980
Cdd:PRK09525   981 QAEEGTWLNIDGFHMGVGGDDSW 1003
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
45-623 1.73e-158

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 481.95  E-value: 1.73e-158
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   45 GEWNFRYAENLTAP-----FTDWDTLTVPGFIQMQslqkpgqPYGTPHyvntqyPWDGHEKlhpgqipqDYNPIGEYQRS 119
Cdd:COG3250      1 GGWKFRLGDAPEGAkpdfdDSGWDPITVPGDWELD-------LYGLPD------PFVGPWY--------LYNGVGWYRRT 59

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  120 FTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDTFTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQDFWRMSG 197
Cdd:COG3250     60 FTVPASWKGkrVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLKPGENVLAVRVDNPSDGSYLEGQDWWRTSG 139

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  198 LFRSVELFTKPEVHLEDVFVKQSFADDfsSAAVTFDCKVSGAGTVSVVFNGQEQSAEVGEPAEYDSGVVFGKGEvapdve 277
Cdd:COG3250    140 IYRDVWLEATPKVHIEDVFVTPDLDDG--SATLTVEVELENESDAGVTVEVTLLDADGKVVATATAKVTLAAGE------ 211

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  278 edVQDVSFTFAVTDPALWSAEQPNLYEAEIALLREGALVERTGLKVGLRKFELKD-RQMLLNGQRIVFKGVNRHEWSCRT 356
Cdd:COG3250    212 --ENTVTLTLTVPNPKLWSPEDPNLYTLVVTLKDDGKVVDTVSTRFGFRTIEIDGdGGFLLNGKPVFLKGVNRHEDWPDD 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  357 GRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFLQLCDEYGLYVIGETNLETHGTWqklgadgsdewtlpGARPEWRE 436
Cdd:COG3250    290 GRAVTDEAMRRDLELMKEAGFNAVRTSHYPEDPEFYDLCDELGLLVWDEAPFEWHGML--------------GDDPEFLE 355

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  437 NVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWEMSEYFRRTDPSRLVhyegifwnreypatsdmesqmytpvadikk 516
Cdd:COG3250    356 AVEAELREMVRRDRNHPSIILWSGGNESGGGPNFAALYEWVKELDPTRPV------------------------------ 405

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  517 flaehpekpFIMCEYSHAMGNSCGG----------------ITDYTEYAYEEPLYQGGFIWEYMDHGIAVTDPDGKpcfa 580
Cdd:COG3250    406 ---------RFLSEYGHAMPNSLGGgyhqpsdfeeyqalqaLEEYWEAFRRRPRLAGGFIWQLNDYWPEPRDNDGN---- 472

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1421400534  581 yggdfgdrptdreFCVDGLVLP-DRRNTPKMDAVKAAYAPLKIT 623
Cdd:COG3250    473 -------------FCSWGLVDYyDRTPKPAYYEVKSAWQPVLVS 503
Glyco_hydro_2_C pfam02836
Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, ...
 328-622 1.50e-114

Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 397119 [Multi-domain]  Cd Length: 302  Bit Score: 354.83  E-value: 1.50e-114
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  328 FELKDRQMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFLQLCDEYGLYVIGETN 407
Cdd:pfam02836    1 VEVKDGLFLINGKPFYFRGVNRHEDHDRRGRGFDMDLMVKDIQLMKQNNINAVRTSHYPNHPEWYQLCDEYGIYVIDEAN 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  408 LETHGTWQKLGADGSDeWTLPGARPEWRENVLARAEAMLERDKNHPAILIWSCGNESHGGKTLWEMSEYFRRTDPSRLVH 487
Cdd:pfam02836   81 LETHGLWQKFGEIEPS-YSELTDNPEWLPAHLERAEELVQRDKNHPSVIIWSLGNESGAGENIAAMYAATKSLDPTRPVH 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  488 YEGIFWNREYPA-TSDMESQMYTPV---ADIKKFL---AEHPEKPFIMCEYSHAMGNSCGGITDYTEYAYEEPLYQGGFI 560
Cdd:pfam02836  160 YEGVGIDPEVDDiILDIYSRMYEDYghpEVIEKYLedwYKKPQKPIIICEYGHAMGNSPGGLQEYQDLFYKYPEYQGGFI 239

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1421400534  561 WEYMDHGIAVTDP-DGKPCFAYGGDFGDRPTDREFCVDGLVLPDRRNTPKMDAVKAAYAPLKI 622
Cdd:pfam02836  240 WDWHDQGIQKRDPnVGGEWYWYGGDFGDRPSDYRFCGNGLFFADRTPKPALFELKKRYWPIKI 302
Bgal_small_N smart01038
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 737-1002 3.07e-68

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 214988 [Multi-domain]  Cd Length: 272  Bit Score: 229.39  E-value: 3.07e-68
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   737 KGKGFEYIFGRGKG-LVSIRYNGVQLLDDTVRPNFWRAPTNNDEGCAEPFTFAFWKTAGLYARCDNLTAEA--KDEFVIV 813
Cdd:smart01038    1 SGGGFSYTFDKATGaLTSWTYNGKELLLRGPKPNFWRAPTDNDRGNGPNAWAARWKAAGLDRLTTRVRSVEveQDSDVVV 80

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   814 RANYTLPDGQTLPID----FAIDGAGRCDITMTWQGAR---TELPEFGLLFPLRRELTEVSYLGLGPRETTADRTAGGKM 886
Cdd:smart01038   81 TVEYLLAAPSGWGFTvtvtYTIDGDGEVKVDVTFTPGGgalPDLPRIGLRFRLPDELEQVEWYGRGPGENYPDRKQSARL 160

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   887 GAWSYNVRQDFaqnTP-VYPQECGSRTDVYSAAVTGSGLNiGIGF-AGDSMTFSALPYTPHELENARHLYELPRDDNkTV 964
Cdd:smart01038  161 GRYSSTVDDLF---TPyVRPQENGNRTDVRWLTLTDDAGN-GLRVtADQPFSFSALPYSAEDLEEAKHPHELPPRDG-TV 235

                           250       260       270
                    ....*....|....*....|....*....|....*...
gi 1421400534   965 VRCAAFQRGVGGDNSWGAKPHADDCFAVEKgTSFRFTI 1002
Cdd:smart01038  236 LNLDAKQMGVGGDDSWGPGVLPEYRLPADE-YSFSFTL 272
Bgal_small_N pfam02929
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 737-1002 2.60e-60

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 460751  Cd Length: 223  Bit Score: 205.41  E-value: 2.60e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  737 KGKGFEYIFGRGKG-LVSIRYNGVQLLDD--TVRPNFWRAPTNNDegcaepftfafwktaglyarcdnltaeakdefviV 813
Cdd:pfam02929    1 SGGDFSYTFDKATGtLTSYKYDGKELLTEplTGRPNFWRAPTDND----------------------------------V 46

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  814 RANYTlpdgqtlpidfaIDGAGRCDITMTWQGART----ELPEFGLLFPLRRELTEVSYLGLGPRETTADRTAGGKMGAW 889
Cdd:pfam02929   47 TVTYT------------IYGDGTIKVDVTLKPDGLkglpELPRFGLRLQLPKSFEQVEWYGRGPGENYPDRKTGARLGIY 114

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  890 SYNVRQDFaqnTP-VYPQECGSRTDVYSAAVT-GSGLNIGIGFAGDSMTFSALPYTPHELENARHLYELPRDDnKTVVRC 967
Cdd:pfam02929  115 ESTVDDLF---TPyIRPQENGNRTDVRWLTLTdGDGGGLLVFVGDGPFSFSALPYTPEELEAAKHPYELPKSD-ETVLNL 190

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1421400534  968 AAFQRGVgGDNSWGAKPHADDCFAVEKgTSFRFTI 1002
Cdd:pfam02929  191 DYAQMGV-GDNSWGPGVLPEYRLPAKE-YSFSFTL 223
PRK10150 PRK10150
beta-D-glucuronidase; Provisional
 116-531 1.13e-43

beta-D-glucuronidase; Provisional


Pssm-ID: 236657 [Multi-domain]  Cd Length: 604  Bit Score: 168.64  E-value: 1.13e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  116 YQRSFTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDTFTPAEFDMTAAVHPGE---------NTLTVQVyrFSSG 184
Cdd:PRK10150    69 YQREVFIPKGWAGqrIVLRFGSVTHYAKVWVNGQEVMEHKGGYTPFEADITPYVYAGKsvritvcvnNELNWQT--LPPG 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  185 SWLEDQ----------DFWRMSGLFRSVELFTKPEVHLEDVFVKQSFADDFSSAAVTFDCKVSGAG-TVSVVFNGQEQsA 253
Cdd:PRK10150   147 NVIEDGngkkkqkynfDFFNYAGIHRPVMLYTTPKTHIDDITVVTELAQDLNHASVDWSVETNGDVdSVSVTLRDADG-Q 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  254 EVGEpAEYDSGVVFgkgevapdveedvqdvsftfaVTDPALWSAEQPNLYEAEIALLREGALVERTGLKVGLRKFELKDR 333
Cdd:PRK10150   226 VVAT-GQGTSGTLQ---------------------VVNPHLWQPGEGYLYTLCVELAKSGTECDTYPLRFGIRSVAVKGG 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  334 QMLLNGQRIVFKGVNRHEWSCRTGRTVSREEMLWDVKNLKAHNVNAVRTSHYPDDPYFLQLCDEYGLYVIGET-----NL 408
Cdd:PRK10150   284 QFLINGKPFYFKGFGKHEDADIRGKGLDEVLNVHDHNLMKWIGANSFRTSHYPYSEEMLDLADRHGIVVIDETpavglNL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  409 eTHGTWQKLGADGSDEWTLPGARPEWREnvlARAEAMLE---RDKNHPAILIWSCGNE--SH--GGKtlwemsEYF---- 477
Cdd:PRK10150   364 -SFGAGLEAGNKPKETYSEEAVNGETQQ---AHLQAIREliaRDKNHPSVVMWSIANEpaSReqGAR------EYFapla 433

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1421400534  478 ---RRTDPSRLVHYEGIFW-----------------NRE---YPATSDMESQMYTPVADIKKFlAEHPEKPFIMCEY 531
Cdd:PRK10150   434 eltRKLDPTRPVTCVNVMFatpdtdtvsdlvdvlclNRYygwYVDSGDLETAEKVLEKELLAW-QEKLHKPIIITEY 509
Glyco_hydro_2_N pfam02837
Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, ...
 42-208 4.60e-34

Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.


Pssm-ID: 397120 [Multi-domain]  Cd Length: 169  Bit Score: 128.52  E-value: 4.60e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534   42 SLDGEWNFR-YAENLTAPFTDW-------DTLTVPGFIQMQslqkpgqpygtPHYVNTQYPWDghekLHPGQIPqDYNPI 113
Cdd:pfam02837    3 SLNGEWAFAlFDAPCGAPQSWWesalqesRTIAVPSSWNDQ-----------PIYTNVEYPID----FADPFIP-TYNGT 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  114 GEYQRSFTLPESWAS--CYLRLNGADSAAAVWCNGVYIGYTEDTFTPAEFDMTAAVHPGENTLTVQVYRFSSGSWLEDQ- 190
Cdd:pfam02837   67 GWYQRTFFIPSKWAGqrIRLRFDGVTHYGEVWVNGQWVGEHQGGYTPFEFDLTPYVIAGKNRIAVKVLNWSDG*YIEDQn 146

                          170       180
                   ....*....|....*....|...
gi 1421400534  191 -----DFWRMSGLFRSVELFTKP 208
Cdd:pfam02837  147 gkyfhDFWNYSGIYRDVSLLTTP 169
LacZ_4 pfam16353
Beta-galactosidase, domain 4; This entry represents domain 4 found in beta-galactosidase and ...
 630-711 4.01e-14

Beta-galactosidase, domain 4; This entry represents domain 4 found in beta-galactosidase and it is organized in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013).


Pssm-ID: 465101 [Multi-domain]  Cd Length: 88  Bit Score: 68.75  E-value: 4.01e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  630 VIENRNLFTDLNAYDLVFASSVNGKPERRAVLRA-DCAPGETVHLLFPFALPETGLACM-TVTAIQRAAKPGIPAGYEAA 707
Cdd:pfam16353    2 TITNRYDFTDLDDYDLSWELLADGKVVASGTLELpDVAPGESATVTLPLPLPGLAGEYFlTVSFRLKEDTPWAPAGHEVA 81


                   ....
gi 1421400534  708 FGQV 711
Cdd:pfam16353   82 WEQF 85
Glyco_hydro_2 pfam00703
Glycosyl hydrolases family 2; This family contains beta-galactosidase, beta-mannosidase and ...
 210-326 1.99e-12

Glycosyl hydrolases family 2; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 395572 [Multi-domain]  Cd Length: 106  Bit Score: 64.42  E-value: 1.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  210 VHLEDVFVKQSFADDfSSAAVTFDCKVSGAGTVSVvfngqeqSAEVGEpaeYDSGVVFGKGEVAPDVEEDVQDVSFTFAV 289
Cdd:pfam00703    1 VHIEDVFITPDLDDD-KTAKVTVEVELENDGDASV-------EVTLET---EIKDADGKTVAAAAKVLVLGAGETTELEV 69

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1421400534  290 TDPALWSAEQPNLYEAEIALLREGALVERTGLKVGLR 326
Cdd:pfam00703   70 KNPKLWSPETPNLYTLTVELDKDGKVIDEVSTRFGFR 106
COG3934 COG3934
Endo-1,4-beta-mannosidase [Carbohydrate transport and metabolism];
337-486 2.32e-04

Endo-1,4-beta-mannosidase [Carbohydrate transport and metabolism];


Pssm-ID: 443135 [Multi-domain]  Cd Length: 331  Bit Score: 44.57  E-value: 2.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  337 LNGQRIVFKGVN---RHEWsCRTGRTVSREEMLWDVKNLKAHNVNAVRT-----------SHYPDDP-----YFLQLCDE 397
Cdd:COG3934      1 LDGKPYFFLGVNywpRAGG-FHMWRDWDPDRVRRELDDLAALGLDVVRVfllwedfqpnpGLINEEAlerldYFLDAAAE 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1421400534  398 YGLYVI-GETNLETHGtwQKLGADGSDEWTLPGAR------PEWRENVLARAEAMLERDKNHPAILIWSCGNESHGGK-- 468
Cdd:COG3934     80 RGLKVVlTLFNNWWSG--HMSGYNWLPSWVGGWHRrnfytdPEAVEAQKAYVRTLANRYKDDPAILGWELGNEPRNFGdp 157

                          170       180
                   ....*....|....*....|....*.
gi 1421400534  469 ------TLW--EMSEYFRRTDPSRLV 486
Cdd:COG3934    158 aspeaaLAWlrEMAAAIKSLDPNHLV 183
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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