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Conserved domains on  [gi|14211770|gb|AAK57507|]
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core-spike protein lambda-2 [Mammalian orthoreovirus 1]

Protein Classification

Reovirus_L2 domain-containing protein( domain architecture ID 10532662)

Reovirus_L2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Reovirus_L2 pfam06016
Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike ...
 1-1288 0e+00

Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike protein lambda-2 (L2) sequences. The reovirus L2 genome segment encodes the core spike protein lambda-2, which mediates enzymatic reactions in 5' capping of the viral plus-strand transcripts.


:

Pssm-ID: 283634  Cd Length: 1297  Bit Score: 2161.22  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770      1 MANVWGVRLADSLSSPT----------------IETRTRHYTLRdfcSDLDAvagkepwrplrNQRTNDIVAVQLFRPLQ 64
Cdd:pfam06016    1 MAAVWGIQLVDKLNTPTtrrtflplrfdllldrLETRTRHYVLH---RALDF-----------NPRTRSATVVQLYPPLN 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770     65 GLVLDTQFYGFPGIFSEWEQFIKEKLRVLKYEVLRIYPISNYNHERVNVFVANALVGAFLS--------NQAFYDllPLL 136
Cdd:pfam06016   67 AWVPDTAFYGFPGDYRDWEEFIHERLRVFKYVLLQRYPITNYANRYVNPLVAGAAFGDFLNarsidiflNQLFYD--PLL 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    137 vinDTMINDLLGTGAALSQFFQSHGEVLEVAAGRKYLQMKNYSNDDDDPPLFAKDLSDYAKAFYSDTFETLDRFFWTHDS 216
Cdd:pfam06016  145 ---DSPITDILGFPYQWTQFFQVHGDVLRTAAGCKYLQMYNYSSRDDTPPTYGKHRPDYATVFYYDTLEARSRFLATHDA 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    217 SAGVLVHYDKPTNGNHYILGTLTQMVSAPPHIINATDALLLESCLEQFAANVRARPAQPVARLDQCYHLRWGAQYVGEDS 296
Cdd:pfam06016  222 GPTVLEHFDSPTYGPHYLLPQLGDVLGYPSSIISQADLLMLESVMDQLRANVRASASTAVTRLDQCYHPVWGFDPVGEDS 301

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    297 LTYRLGVLSLLATNGYQLARPIPKQLTNRWLSSFVSQVMSDGVNETplWPQERYVQIAY--DSPSVVDGATHYGYVRrnQ 374
Cdd:pfam06016  302 LTYRLTNLALLAVQGYQLERAIPAQPTNRDVRSFVARLMSEGVNQT--WFPYRYDQILYwpDSPFVVPGGTFYAYVR--Q 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    375 LRLGMRVSALQSLSDTPAPIQWLPQY-----TIEQAAVDEGDLMVSrltqlPLRPDYGSIWVGDALSYYVDYNRSHRVVL 449
Cdd:pfam06016  378 LNFPFTTGAYTSVPDAPRPLRWLPQYrnatiTIQQAADAYEDLMVS-----PLRPDHGFCWVGGVLSYYVDISRDPTVVP 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    450 SSELPQLPDTYFDGDEQYGRSLFSLARKIGDRSLIKDTAVLKHAYQAIDPNTGKEYLRAGQSVAYFGASAGHSGADQPLV 529
Cdd:pfam06016  453 SSELPQLPDTYFDGDRMARRSLFRRLRKPGDRSLIKDTAVFKFLASLVNPNTAKPYLRTGFSVAYLGASAAHAGADEPLI 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    530 IEPWTQGKISGVPPPSSVRQFGYDVAKGAIVDLARPFPSGDYQFVYSDVDQVVDGHDDLSISSGLVESLLDSCMHATSPG 609
Cdd:pfam06016  533 LADWRQGSIPGLPIPSRIRQFGYDVVHGSLLDLARAVPTGTFGLVYADLDQVEDAGTDLPAANRAAEAMLGTCLQMTTAG 612

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    610 GSFVMKINFPTRTVWHYIEQKILPNITSYMLIKPFVTNNVELFFVAFGVHQQSALTWTSGVYFFLVDHFYRYETLSTISR 689
Cdd:pfam06016  613 GVFVLKVNFPTRAFWTQIFNKYATNATTLHLVKPFVVNSSEVFFVAFGRQSNGALTWTTGLQRALLDHYARNAAIDTIST 692

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    690 QLPSFGYVDDGSSVTGIEMISLENPGFSN-MTQAARVGISGLCANVGNARKLISIHESHGARVLTITSRRSPASARRKAR 768
Cdd:pfam06016  693 HLPSFGYVDDGTSVLGIEAIRLFDPGFSNaMTNAARNALAGLCANVVPSSIMISRVPSNGPVSTTITGKRTFLSARRRAR 772

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    769 LRYLPLVDPRSLEVQARTILPSNPVLFdnvngASPHVCLTMM----YNFEVSSAVYDGDV--VLDLGTGPEAKILELIPP 842
Cdd:pfam06016  773 LRYLPLLDPTSLEHQRRFTLPPTFVLF-----ASEHVCVTTLvaagYNFEVSSAVYDGDVahLLDLGTGPECRILSLIPP 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    843 TSPVTCVDIRPTAQPSGCWNVRTT-FLELDYLSDGWITGIRGDIVTCMLSLGAAAAGKSMTFDAAFQQLVKVLTKSTANV 921
Cdd:pfam06016  848 TSPVTMVDIRPCAELMGCWDPRTTaYLQLDYLSAAFWNGIRCDIVTAIFTLGAAAAGKSMTFDAAFQQLIPVIVKAGATR 927

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    922 LLIQVNCPTDVIRTIKGYLEIDQTNKRYRFPKFGRDEPYSDMDSLERICRAAWPNCSITWVPLSYDLRWTKLALLESTTL 1001
Cdd:pfam06016  928 LWLQVNCPLDVVRSIPGLIEIDLRNKRYRFNKGERDEPYSDPDPLQQICRAAWPNASLSWVTLSPTCRWLPYIIGEGSTL 1007

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1002 SSASVRIAELMYKYMPVMRIDIHGLPMEKqgNFI---VGQNCSLTIPGFNAQDVFNCYFNSALAFS-TEDVNSAMIPQVT 1077
Cdd:pfam06016 1008 SLSSIRTAELYSKLTPILRIDTHGLPLRV--NPIptpLGQQCAIRIPGFDPAAVLNCYHNGVLVISgTPDVNISMIGQAA 1085

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1078 AQFDANKGEWSLDMVFSDAGIYTMqALVGSNANPVSLGSFVVDSP--DVDITDAWPAQLDFTIAGTDVDITVNPYYRLMA 1155
Cdd:pfam06016 1086 LQYIAANGEFLLQMTPTLAGIFDV-ALTGSGQPPVPRGSFTITSPptTVDITMAWPAQLDFTDAGNDVDITCDPYYRLAV 1164

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1156 FVRIDGQWQIANPDKFQFFSSSTGTlVMNVKLDIADRYLLYYIRDVQSRDVGFYIQHPLQLLNTITLPTNEDLFLSAPDM 1235
Cdd:pfam06016 1165 CIRIDGQYVRVNPEKAQVFTSAPGR-VLHFVLDLADNHVLYYLCDVTPRDVGFYIAHPLQDIYTITFPTNTPLRASLPYM 1243

                         1290      1300      1310      1320      1330
                   ....*....|....*....|....*....|....*....|....*....|....
gi 14211770   1236 REWA-VKESGNTICILNSQGFVPPQDWDVLTDTISWSPSLPTYVVPPGDYTLTP 1288
Cdd:pfam06016 1244 GGGAhVKESGNPICSLTSPPFVLPAGWALAALTTSWSPSYPTYTLPAGDYTYVP 1297
 
Name Accession Description Interval E-value
Reovirus_L2 pfam06016
Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike ...
 1-1288 0e+00

Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike protein lambda-2 (L2) sequences. The reovirus L2 genome segment encodes the core spike protein lambda-2, which mediates enzymatic reactions in 5' capping of the viral plus-strand transcripts.


Pssm-ID: 283634  Cd Length: 1297  Bit Score: 2161.22  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770      1 MANVWGVRLADSLSSPT----------------IETRTRHYTLRdfcSDLDAvagkepwrplrNQRTNDIVAVQLFRPLQ 64
Cdd:pfam06016    1 MAAVWGIQLVDKLNTPTtrrtflplrfdllldrLETRTRHYVLH---RALDF-----------NPRTRSATVVQLYPPLN 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770     65 GLVLDTQFYGFPGIFSEWEQFIKEKLRVLKYEVLRIYPISNYNHERVNVFVANALVGAFLS--------NQAFYDllPLL 136
Cdd:pfam06016   67 AWVPDTAFYGFPGDYRDWEEFIHERLRVFKYVLLQRYPITNYANRYVNPLVAGAAFGDFLNarsidiflNQLFYD--PLL 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    137 vinDTMINDLLGTGAALSQFFQSHGEVLEVAAGRKYLQMKNYSNDDDDPPLFAKDLSDYAKAFYSDTFETLDRFFWTHDS 216
Cdd:pfam06016  145 ---DSPITDILGFPYQWTQFFQVHGDVLRTAAGCKYLQMYNYSSRDDTPPTYGKHRPDYATVFYYDTLEARSRFLATHDA 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    217 SAGVLVHYDKPTNGNHYILGTLTQMVSAPPHIINATDALLLESCLEQFAANVRARPAQPVARLDQCYHLRWGAQYVGEDS 296
Cdd:pfam06016  222 GPTVLEHFDSPTYGPHYLLPQLGDVLGYPSSIISQADLLMLESVMDQLRANVRASASTAVTRLDQCYHPVWGFDPVGEDS 301

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    297 LTYRLGVLSLLATNGYQLARPIPKQLTNRWLSSFVSQVMSDGVNETplWPQERYVQIAY--DSPSVVDGATHYGYVRrnQ 374
Cdd:pfam06016  302 LTYRLTNLALLAVQGYQLERAIPAQPTNRDVRSFVARLMSEGVNQT--WFPYRYDQILYwpDSPFVVPGGTFYAYVR--Q 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    375 LRLGMRVSALQSLSDTPAPIQWLPQY-----TIEQAAVDEGDLMVSrltqlPLRPDYGSIWVGDALSYYVDYNRSHRVVL 449
Cdd:pfam06016  378 LNFPFTTGAYTSVPDAPRPLRWLPQYrnatiTIQQAADAYEDLMVS-----PLRPDHGFCWVGGVLSYYVDISRDPTVVP 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    450 SSELPQLPDTYFDGDEQYGRSLFSLARKIGDRSLIKDTAVLKHAYQAIDPNTGKEYLRAGQSVAYFGASAGHSGADQPLV 529
Cdd:pfam06016  453 SSELPQLPDTYFDGDRMARRSLFRRLRKPGDRSLIKDTAVFKFLASLVNPNTAKPYLRTGFSVAYLGASAAHAGADEPLI 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    530 IEPWTQGKISGVPPPSSVRQFGYDVAKGAIVDLARPFPSGDYQFVYSDVDQVVDGHDDLSISSGLVESLLDSCMHATSPG 609
Cdd:pfam06016  533 LADWRQGSIPGLPIPSRIRQFGYDVVHGSLLDLARAVPTGTFGLVYADLDQVEDAGTDLPAANRAAEAMLGTCLQMTTAG 612

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    610 GSFVMKINFPTRTVWHYIEQKILPNITSYMLIKPFVTNNVELFFVAFGVHQQSALTWTSGVYFFLVDHFYRYETLSTISR 689
Cdd:pfam06016  613 GVFVLKVNFPTRAFWTQIFNKYATNATTLHLVKPFVVNSSEVFFVAFGRQSNGALTWTTGLQRALLDHYARNAAIDTIST 692

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    690 QLPSFGYVDDGSSVTGIEMISLENPGFSN-MTQAARVGISGLCANVGNARKLISIHESHGARVLTITSRRSPASARRKAR 768
Cdd:pfam06016  693 HLPSFGYVDDGTSVLGIEAIRLFDPGFSNaMTNAARNALAGLCANVVPSSIMISRVPSNGPVSTTITGKRTFLSARRRAR 772

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    769 LRYLPLVDPRSLEVQARTILPSNPVLFdnvngASPHVCLTMM----YNFEVSSAVYDGDV--VLDLGTGPEAKILELIPP 842
Cdd:pfam06016  773 LRYLPLLDPTSLEHQRRFTLPPTFVLF-----ASEHVCVTTLvaagYNFEVSSAVYDGDVahLLDLGTGPECRILSLIPP 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    843 TSPVTCVDIRPTAQPSGCWNVRTT-FLELDYLSDGWITGIRGDIVTCMLSLGAAAAGKSMTFDAAFQQLVKVLTKSTANV 921
Cdd:pfam06016  848 TSPVTMVDIRPCAELMGCWDPRTTaYLQLDYLSAAFWNGIRCDIVTAIFTLGAAAAGKSMTFDAAFQQLIPVIVKAGATR 927

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    922 LLIQVNCPTDVIRTIKGYLEIDQTNKRYRFPKFGRDEPYSDMDSLERICRAAWPNCSITWVPLSYDLRWTKLALLESTTL 1001
Cdd:pfam06016  928 LWLQVNCPLDVVRSIPGLIEIDLRNKRYRFNKGERDEPYSDPDPLQQICRAAWPNASLSWVTLSPTCRWLPYIIGEGSTL 1007

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1002 SSASVRIAELMYKYMPVMRIDIHGLPMEKqgNFI---VGQNCSLTIPGFNAQDVFNCYFNSALAFS-TEDVNSAMIPQVT 1077
Cdd:pfam06016 1008 SLSSIRTAELYSKLTPILRIDTHGLPLRV--NPIptpLGQQCAIRIPGFDPAAVLNCYHNGVLVISgTPDVNISMIGQAA 1085

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1078 AQFDANKGEWSLDMVFSDAGIYTMqALVGSNANPVSLGSFVVDSP--DVDITDAWPAQLDFTIAGTDVDITVNPYYRLMA 1155
Cdd:pfam06016 1086 LQYIAANGEFLLQMTPTLAGIFDV-ALTGSGQPPVPRGSFTITSPptTVDITMAWPAQLDFTDAGNDVDITCDPYYRLAV 1164

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1156 FVRIDGQWQIANPDKFQFFSSSTGTlVMNVKLDIADRYLLYYIRDVQSRDVGFYIQHPLQLLNTITLPTNEDLFLSAPDM 1235
Cdd:pfam06016 1165 CIRIDGQYVRVNPEKAQVFTSAPGR-VLHFVLDLADNHVLYYLCDVTPRDVGFYIAHPLQDIYTITFPTNTPLRASLPYM 1243

                         1290      1300      1310      1320      1330
                   ....*....|....*....|....*....|....*....|....*....|....
gi 14211770   1236 REWA-VKESGNTICILNSQGFVPPQDWDVLTDTISWSPSLPTYVVPPGDYTLTP 1288
Cdd:pfam06016 1244 GGGAhVKESGNPICSLTSPPFVLPAGWALAALTTSWSPSYPTYTLPAGDYTYVP 1297
 
Name Accession Description Interval E-value
Reovirus_L2 pfam06016
Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike ...
 1-1288 0e+00

Reovirus core-spike protein lambda-2 (L2); This family consists of several Reovirus core-spike protein lambda-2 (L2) sequences. The reovirus L2 genome segment encodes the core spike protein lambda-2, which mediates enzymatic reactions in 5' capping of the viral plus-strand transcripts.


Pssm-ID: 283634  Cd Length: 1297  Bit Score: 2161.22  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770      1 MANVWGVRLADSLSSPT----------------IETRTRHYTLRdfcSDLDAvagkepwrplrNQRTNDIVAVQLFRPLQ 64
Cdd:pfam06016    1 MAAVWGIQLVDKLNTPTtrrtflplrfdllldrLETRTRHYVLH---RALDF-----------NPRTRSATVVQLYPPLN 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770     65 GLVLDTQFYGFPGIFSEWEQFIKEKLRVLKYEVLRIYPISNYNHERVNVFVANALVGAFLS--------NQAFYDllPLL 136
Cdd:pfam06016   67 AWVPDTAFYGFPGDYRDWEEFIHERLRVFKYVLLQRYPITNYANRYVNPLVAGAAFGDFLNarsidiflNQLFYD--PLL 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    137 vinDTMINDLLGTGAALSQFFQSHGEVLEVAAGRKYLQMKNYSNDDDDPPLFAKDLSDYAKAFYSDTFETLDRFFWTHDS 216
Cdd:pfam06016  145 ---DSPITDILGFPYQWTQFFQVHGDVLRTAAGCKYLQMYNYSSRDDTPPTYGKHRPDYATVFYYDTLEARSRFLATHDA 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    217 SAGVLVHYDKPTNGNHYILGTLTQMVSAPPHIINATDALLLESCLEQFAANVRARPAQPVARLDQCYHLRWGAQYVGEDS 296
Cdd:pfam06016  222 GPTVLEHFDSPTYGPHYLLPQLGDVLGYPSSIISQADLLMLESVMDQLRANVRASASTAVTRLDQCYHPVWGFDPVGEDS 301

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    297 LTYRLGVLSLLATNGYQLARPIPKQLTNRWLSSFVSQVMSDGVNETplWPQERYVQIAY--DSPSVVDGATHYGYVRrnQ 374
Cdd:pfam06016  302 LTYRLTNLALLAVQGYQLERAIPAQPTNRDVRSFVARLMSEGVNQT--WFPYRYDQILYwpDSPFVVPGGTFYAYVR--Q 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    375 LRLGMRVSALQSLSDTPAPIQWLPQY-----TIEQAAVDEGDLMVSrltqlPLRPDYGSIWVGDALSYYVDYNRSHRVVL 449
Cdd:pfam06016  378 LNFPFTTGAYTSVPDAPRPLRWLPQYrnatiTIQQAADAYEDLMVS-----PLRPDHGFCWVGGVLSYYVDISRDPTVVP 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    450 SSELPQLPDTYFDGDEQYGRSLFSLARKIGDRSLIKDTAVLKHAYQAIDPNTGKEYLRAGQSVAYFGASAGHSGADQPLV 529
Cdd:pfam06016  453 SSELPQLPDTYFDGDRMARRSLFRRLRKPGDRSLIKDTAVFKFLASLVNPNTAKPYLRTGFSVAYLGASAAHAGADEPLI 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    530 IEPWTQGKISGVPPPSSVRQFGYDVAKGAIVDLARPFPSGDYQFVYSDVDQVVDGHDDLSISSGLVESLLDSCMHATSPG 609
Cdd:pfam06016  533 LADWRQGSIPGLPIPSRIRQFGYDVVHGSLLDLARAVPTGTFGLVYADLDQVEDAGTDLPAANRAAEAMLGTCLQMTTAG 612

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    610 GSFVMKINFPTRTVWHYIEQKILPNITSYMLIKPFVTNNVELFFVAFGVHQQSALTWTSGVYFFLVDHFYRYETLSTISR 689
Cdd:pfam06016  613 GVFVLKVNFPTRAFWTQIFNKYATNATTLHLVKPFVVNSSEVFFVAFGRQSNGALTWTTGLQRALLDHYARNAAIDTIST 692

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    690 QLPSFGYVDDGSSVTGIEMISLENPGFSN-MTQAARVGISGLCANVGNARKLISIHESHGARVLTITSRRSPASARRKAR 768
Cdd:pfam06016  693 HLPSFGYVDDGTSVLGIEAIRLFDPGFSNaMTNAARNALAGLCANVVPSSIMISRVPSNGPVSTTITGKRTFLSARRRAR 772

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    769 LRYLPLVDPRSLEVQARTILPSNPVLFdnvngASPHVCLTMM----YNFEVSSAVYDGDV--VLDLGTGPEAKILELIPP 842
Cdd:pfam06016  773 LRYLPLLDPTSLEHQRRFTLPPTFVLF-----ASEHVCVTTLvaagYNFEVSSAVYDGDVahLLDLGTGPECRILSLIPP 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    843 TSPVTCVDIRPTAQPSGCWNVRTT-FLELDYLSDGWITGIRGDIVTCMLSLGAAAAGKSMTFDAAFQQLVKVLTKSTANV 921
Cdd:pfam06016  848 TSPVTMVDIRPCAELMGCWDPRTTaYLQLDYLSAAFWNGIRCDIVTAIFTLGAAAAGKSMTFDAAFQQLIPVIVKAGATR 927

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770    922 LLIQVNCPTDVIRTIKGYLEIDQTNKRYRFPKFGRDEPYSDMDSLERICRAAWPNCSITWVPLSYDLRWTKLALLESTTL 1001
Cdd:pfam06016  928 LWLQVNCPLDVVRSIPGLIEIDLRNKRYRFNKGERDEPYSDPDPLQQICRAAWPNASLSWVTLSPTCRWLPYIIGEGSTL 1007

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1002 SSASVRIAELMYKYMPVMRIDIHGLPMEKqgNFI---VGQNCSLTIPGFNAQDVFNCYFNSALAFS-TEDVNSAMIPQVT 1077
Cdd:pfam06016 1008 SLSSIRTAELYSKLTPILRIDTHGLPLRV--NPIptpLGQQCAIRIPGFDPAAVLNCYHNGVLVISgTPDVNISMIGQAA 1085

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1078 AQFDANKGEWSLDMVFSDAGIYTMqALVGSNANPVSLGSFVVDSP--DVDITDAWPAQLDFTIAGTDVDITVNPYYRLMA 1155
Cdd:pfam06016 1086 LQYIAANGEFLLQMTPTLAGIFDV-ALTGSGQPPVPRGSFTITSPptTVDITMAWPAQLDFTDAGNDVDITCDPYYRLAV 1164

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14211770   1156 FVRIDGQWQIANPDKFQFFSSSTGTlVMNVKLDIADRYLLYYIRDVQSRDVGFYIQHPLQLLNTITLPTNEDLFLSAPDM 1235
Cdd:pfam06016 1165 CIRIDGQYVRVNPEKAQVFTSAPGR-VLHFVLDLADNHVLYYLCDVTPRDVGFYIAHPLQDIYTITFPTNTPLRASLPYM 1243

                         1290      1300      1310      1320      1330
                   ....*....|....*....|....*....|....*....|....*....|....
gi 14211770   1236 REWA-VKESGNTICILNSQGFVPPQDWDVLTDTISWSPSLPTYVVPPGDYTLTP 1288
Cdd:pfam06016 1244 GGGAhVKESGNPICSLTSPPFVLPAGWALAALTTSWSPSYPTYTLPAGDYTYVP 1297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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