NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|14150141|ref|NP_115722|]
View 

programmed cell death protein 2-like isoform 1 [Homo sapiens]

Protein Classification

programmed cell death 2 domain-containing protein( domain architecture ID 10514769)

programmed cell death 2 domain-containing protein similar to human programmed cell death protein 2-like and Saccharomyces cerevisiae 20S rRNA accumulation protein 4 that is required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA

Gene Ontology:  GO:0005737

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PDCD2_C pfam04194
Programmed cell death protein 2, C-terminal putative domain;
247-350 3.01e-47

Programmed cell death protein 2, C-terminal putative domain;


:

Pssm-ID: 461221  Cd Length: 111  Bit Score: 155.84  E-value: 3.01e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14150141   247 DQTFYKFMKRIAACQEQILRYSWSGEPLFLT--CPTSEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGL-SVEFGT 323
Cdd:pfam04194   1 DKTFQKFQKRIAANPEQVLRYSFGGKPLWYSseGRPSLASDIPNCENCGGPRVFEFQLMPQLINYLEVDDESDdGMDWGT 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 14150141   324 ILVYTCEKSC----WPPNHQTPMEEFCIIQE 350
Cdd:pfam04194  81 IIVYTCSKSCdppeWDEGDVGYVEEFVWVQW 111
 
Name Accession Description Interval E-value
PDCD2_C pfam04194
Programmed cell death protein 2, C-terminal putative domain;
247-350 3.01e-47

Programmed cell death protein 2, C-terminal putative domain;


Pssm-ID: 461221  Cd Length: 111  Bit Score: 155.84  E-value: 3.01e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14150141   247 DQTFYKFMKRIAACQEQILRYSWSGEPLFLT--CPTSEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGL-SVEFGT 323
Cdd:pfam04194   1 DKTFQKFQKRIAANPEQVLRYSFGGKPLWYSseGRPSLASDIPNCENCGGPRVFEFQLMPQLINYLEVDDESDdGMDWGT 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 14150141   324 ILVYTCEKSC----WPPNHQTPMEEFCIIQE 350
Cdd:pfam04194  81 IIVYTCSKSCdppeWDEGDVGYVEEFVWVQW 111
 
Name Accession Description Interval E-value
PDCD2_C pfam04194
Programmed cell death protein 2, C-terminal putative domain;
247-350 3.01e-47

Programmed cell death protein 2, C-terminal putative domain;


Pssm-ID: 461221  Cd Length: 111  Bit Score: 155.84  E-value: 3.01e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14150141   247 DQTFYKFMKRIAACQEQILRYSWSGEPLFLT--CPTSEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGL-SVEFGT 323
Cdd:pfam04194   1 DKTFQKFQKRIAANPEQVLRYSFGGKPLWYSseGRPSLASDIPNCENCGGPRVFEFQLMPQLINYLEVDDESDdGMDWGT 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 14150141   324 ILVYTCEKSC----WPPNHQTPMEEFCIIQE 350
Cdd:pfam04194  81 IIVYTCSKSCdppeWDEGDVGYVEEFVWVQW 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH