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Conserved domains on  [gi|1408134723|gb|RAL25560|]
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hypothetical protein DL240_04600 [Lujinxingia litoralis]

Protein Classification

HmuY family protein( domain architecture ID 10186683)

HmuY family protein is a heme-binding protein similar to Porphyromonas gingivalis HmuY that sequesters heme from host carriers and delivers it to its cognate outer-membrane transporter, the TonB-dependent receptor HmuR

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HmuY cd12105
Bacterial proteins similar to Porphyromonas gingivalis HmuY; HmuY is a hemophore that ...
 79-153 6.78e-11

Bacterial proteins similar to Porphyromonas gingivalis HmuY; HmuY is a hemophore that scavenges heme from infected hosts and delivers it to the outer membrane receptor HmuR. Related but uncharacterized proteins do not appear to share the specific heme-binding site.


:

Pssm-ID: 213031  Cd Length: 121  Bit Score: 58.09  E-value: 6.78e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1408134723  79 QAGGTQGAASHPFVYLNLATGEKValdDVGAAVSDAWHLAFKRVVIRSNGGYSGPGGVVVAKESATSFEEVTQAP 153
Cdd:cd12105     1 KTTTISKTSSTNWVYFSLDTGKVV---NVEPEEPTDWDIAFHRYDIRTNGGVSGTGKGGAADLKATDLDSAAVAP 72
 
Name Accession Description Interval E-value
HmuY cd12105
Bacterial proteins similar to Porphyromonas gingivalis HmuY; HmuY is a hemophore that ...
 79-153 6.78e-11

Bacterial proteins similar to Porphyromonas gingivalis HmuY; HmuY is a hemophore that scavenges heme from infected hosts and delivers it to the outer membrane receptor HmuR. Related but uncharacterized proteins do not appear to share the specific heme-binding site.


Pssm-ID: 213031  Cd Length: 121  Bit Score: 58.09  E-value: 6.78e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1408134723  79 QAGGTQGAASHPFVYLNLATGEKValdDVGAAVSDAWHLAFKRVVIRSNGGYSGPGGVVVAKESATSFEEVTQAP 153
Cdd:cd12105     1 KTTTISKTSSTNWVYFSLDTGKVV---NVEPEEPTDWDIAFHRYDIRTNGGVSGTGKGGAADLKATDLDSAAVAP 72
HmuY pfam14064
HmuY protein; HmuY is a novel heme-binding protein that recruits heme from host carriers and ...
 92-234 1.61e-10

HmuY protein; HmuY is a novel heme-binding protein that recruits heme from host carriers and delivers it to its cognate outer-membrane transporter, the TonB-dependent receptor HmuR. This family of proteins is found in bacteria. Proteins in this family are typically between 214 and 278 amino acids in length.


Pssm-ID: 464078  Cd Length: 155  Bit Score: 57.78  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1408134723  92 VYLNLATGEKVALDDvGAAVSDAWHLAFKRVVIRSNGGYSGPGgvvvAKESATSFEEV-TQAPGQ----PDAYRSDQ-TY 165
Cdd:pfam14064   6 VYIDLSTGKQVSVTA-APVERTSWDIAFHRYDVKTNGGASGAG----KATNYTDFDAVtTELPANgeyvDDVWTTNEvSY 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1408134723 166 DAScnpqlDPIGTPMT-AFNFLNLNNPSGSqSWYSYGGGVSPVSGD-VYVVRVPEASQAfKVEILGWSDGE 234
Cdd:pfam14064  81 DMS-----DMVLSNSGgTGTFKTDANPILS-SWLNFGTPPIYTLSNhVYVVKTADGNYA-KLQFTDYTNND 144
 
Name Accession Description Interval E-value
HmuY cd12105
Bacterial proteins similar to Porphyromonas gingivalis HmuY; HmuY is a hemophore that ...
 79-153 6.78e-11

Bacterial proteins similar to Porphyromonas gingivalis HmuY; HmuY is a hemophore that scavenges heme from infected hosts and delivers it to the outer membrane receptor HmuR. Related but uncharacterized proteins do not appear to share the specific heme-binding site.


Pssm-ID: 213031  Cd Length: 121  Bit Score: 58.09  E-value: 6.78e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1408134723  79 QAGGTQGAASHPFVYLNLATGEKValdDVGAAVSDAWHLAFKRVVIRSNGGYSGPGGVVVAKESATSFEEVTQAP 153
Cdd:cd12105     1 KTTTISKTSSTNWVYFSLDTGKVV---NVEPEEPTDWDIAFHRYDIRTNGGVSGTGKGGAADLKATDLDSAAVAP 72
HmuY pfam14064
HmuY protein; HmuY is a novel heme-binding protein that recruits heme from host carriers and ...
 92-234 1.61e-10

HmuY protein; HmuY is a novel heme-binding protein that recruits heme from host carriers and delivers it to its cognate outer-membrane transporter, the TonB-dependent receptor HmuR. This family of proteins is found in bacteria. Proteins in this family are typically between 214 and 278 amino acids in length.


Pssm-ID: 464078  Cd Length: 155  Bit Score: 57.78  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1408134723  92 VYLNLATGEKVALDDvGAAVSDAWHLAFKRVVIRSNGGYSGPGgvvvAKESATSFEEV-TQAPGQ----PDAYRSDQ-TY 165
Cdd:pfam14064   6 VYIDLSTGKQVSVTA-APVERTSWDIAFHRYDVKTNGGASGAG----KATNYTDFDAVtTELPANgeyvDDVWTTNEvSY 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1408134723 166 DAScnpqlDPIGTPMT-AFNFLNLNNPSGSqSWYSYGGGVSPVSGD-VYVVRVPEASQAfKVEILGWSDGE 234
Cdd:pfam14064  81 DMS-----DMVLSNSGgTGTFKTDANPILS-SWLNFGTPPIYTLSNhVYVVKTADGNYA-KLQFTDYTNND 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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