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Conserved domains on  [gi|1404710828|gb|PZN70771|]
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MAG: AAA+ family ATPase [Bacillota bacterium]

Protein Classification

ATP-binding protein( domain architecture ID 10529364)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF815 pfam05673
Protein of unknown function (DUF815); This family consists of several bacterial proteins of ...
 182-428 3.83e-128

Protein of unknown function (DUF815); This family consists of several bacterial proteins of unknown function.


:

Pssm-ID: 428578 [Multi-domain]  Cd Length: 250  Bit Score: 370.33  E-value: 3.83e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 182 ASTWFLTWD---GAGLQPVEEPDLVDLDDLAGLEDQKAAVQENTEAFLRGGPGLNLLLYGPRGTGKSSLVRGLALRYGEA 258
Cdd:pfam05673   1 AAAPAFRWRrgeSGALEPVPHPDPVRLDDLVGIERQKEALIRNTRRFLAGLPANNVLLWGARGTGKSSLVKALLNEYADQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 259 GLRLVEVSRDRLGTLGDLYRTVRRYPQRFVLFLDDLTFEADDAEYRAFKSLLEGALERRPPNLVLYVTSNRRHMVPERWS 338
Cdd:pfam05673  81 GLRLIEVDKEDLGDLPDLVDLLRDRPYRFILFCDDLSFEEGESSYKALKSVLEGGLEARPDNVLIYATSNRRHLIPEYMS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 339 DRGSPEEAEVHGQDALEERLSLADRFGRTILFLRPDQEQYLRIVEHLAARRGLPIGREELREAARRWALWQNGLSGRTAR 418
Cdd:pfam05673 161 DNEGLVDGEIHPGDAVEEKLSLSDRFGLWLGFYPFDQDEYLAIVRGYAARLGLPLDEEELRREALQWALTRGGRSGRTAR 240

                         250
                  ....*....|
gi 1404710828 419 QFVDDLEAKL 428
Cdd:pfam05673 241 QFIDDLAGRL 250
 
Name Accession Description Interval E-value
DUF815 pfam05673
Protein of unknown function (DUF815); This family consists of several bacterial proteins of ...
 182-428 3.83e-128

Protein of unknown function (DUF815); This family consists of several bacterial proteins of unknown function.


Pssm-ID: 428578 [Multi-domain]  Cd Length: 250  Bit Score: 370.33  E-value: 3.83e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 182 ASTWFLTWD---GAGLQPVEEPDLVDLDDLAGLEDQKAAVQENTEAFLRGGPGLNLLLYGPRGTGKSSLVRGLALRYGEA 258
Cdd:pfam05673   1 AAAPAFRWRrgeSGALEPVPHPDPVRLDDLVGIERQKEALIRNTRRFLAGLPANNVLLWGARGTGKSSLVKALLNEYADQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 259 GLRLVEVSRDRLGTLGDLYRTVRRYPQRFVLFLDDLTFEADDAEYRAFKSLLEGALERRPPNLVLYVTSNRRHMVPERWS 338
Cdd:pfam05673  81 GLRLIEVDKEDLGDLPDLVDLLRDRPYRFILFCDDLSFEEGESSYKALKSVLEGGLEARPDNVLIYATSNRRHLIPEYMS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 339 DRGSPEEAEVHGQDALEERLSLADRFGRTILFLRPDQEQYLRIVEHLAARRGLPIGREELREAARRWALWQNGLSGRTAR 418
Cdd:pfam05673 161 DNEGLVDGEIHPGDAVEEKLSLSDRFGLWLGFYPFDQDEYLAIVRGYAARLGLPLDEEELRREALQWALTRGGRSGRTAR 240

                         250
                  ....*....|
gi 1404710828 419 QFVDDLEAKL 428
Cdd:pfam05673 241 QFIDDLAGRL 250
Atu1564 COG2607
Predicted ATPase, AAA+ superfamily [General function prediction only];
156-433 1.94e-126

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 442019  Cd Length: 286  Bit Score: 367.50  E-value: 1.94e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 156 LAQAEDWADLVDELAA-------FHRAQGFgpvasTWFLTWDGAGLQPVEEPDLVDLDDLAGLEDQKAAVQENTEAFLRG 228
Cdd:COG2607     7 LARLERLLEALERLLPpppggpdFAAADAF-----RWRRRGGGGRLEPVPHPDPIRLDDLVGIERQKEILIRNTEQFLAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 229 GPGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVSRDRLGTLGDLYRTVRRYPQRFVLFLDDLTFEADDAEYRAFKS 308
Cdd:COG2607    82 LPANNVLLWGARGTGKSSLVKALLNEYADQGLRLIEVDKEDLADLPDIVELLRGRPERFIIFCDDLSFEEDETSYKALKA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 309 LLEGALERRPPNLVLYVTSNRRHMVPERWSDRGSPEEAEVHGQDALEERLSLADRFGRTILFLRPDQEQYLRIVEHLAAR 388
Cdd:COG2607   162 VLEGGLEARPDNVLIYATSNRRHLMPEYMSDNERPVDGEIHPGEAVEEKLSLSDRFGLWLGFYPPDQDEYLAIVRHLAAH 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1404710828 389 RGLPIGREELREAARRWALWQNGLSGRTARQFVDDLEAKLRSQRS 433
Cdd:COG2607   242 FGLDIDDEELRREALQWALTRGGRSGRVAWQFIDDLAGRLGLALD 286
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 209-370 1.75e-09

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 56.00  E-value: 1.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 209 AGLEDQKAAVQEnteaFLRGGPGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEV--SRDRLGTLGDLYRTV------ 280
Cdd:cd00009     1 VGQEEAIEALRE----ALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLnaSDLLEGLVVAELFGHflvrll 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 281 ---RRYPQRFVLFLDD---LTFEADDAEYRAFKSLLEGALERRppNLVLYVTSNRRhmvperwsdrgspeeaevhgqDAL 354
Cdd:cd00009    77 felAEKAKPGVLFIDEidsLSRGAQNALLRVLETLNDLRIDRE--NVRVIGATNRP---------------------LLG 133

                         170
                  ....*....|....*.
gi 1404710828 355 EERLSLADRFGRTILF 370
Cdd:cd00009   134 DLDRALYDRLDIRIVI 149
PRK04195 PRK04195
replication factor C large subunit; Provisional
 205-280 3.62e-06

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 49.15  E-value: 3.62e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1404710828 205 LDDLAGLEDQKAAVQENTEAFLRGGPGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEV--SRDRlgTLGDLYRTV 280
Cdd:PRK04195   13 LSDVVGNEKAKEQLREWIESWLKGKPKKALLLYGPPGVGKTSLAHALA---NDYGWEVIELnaSDQR--TADVIERVA 85
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 230-331 8.23e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 45.44  E-value: 8.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828  230 PGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVS----------------RDRLGTLGDLYRTVR------RYPQRF 287
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDgedileevldqllliiVGGKKASGSGELRLRlalalaRKLKPD 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1404710828  288 VLFLDDLTFEADD---AEYRAFKSLLEGALERRPPNLVLYVTSNRRH 331
Cdd:smart00382  81 VLILDEITSLLDAeqeALLLLLEELRLLLLLKSEKNLTVILTTNDEK 127
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 197-404 5.04e-04

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 42.59  E-value: 5.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 197 VEEPDlVDLDDLAGLEDQKAAVQENTE-------AFLRGG--PGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSR 267
Cdd:TIGR01243 445 VEVPN-VRWSDIGGLEEVKQELREAVEwplkhpeIFEKMGirPPKGVLLFGPPGTGKTLLAKAVA---TESGANFIAVRG 520

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 268 DRLGT--LGDLYRTVRRYPQRF------VLFLDDL--------TFEADDAEYRAFKSLL---EGALErrPPNLVLYVTSN 328
Cdd:TIGR01243 521 PEILSkwVGESEKAIREIFRKArqaapaIIFFDEIdaiapargARFDTSVTDRIVNQLLtemDGIQE--LSNVVVIAATN 598

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1404710828 329 RrhmvperwsdrgspeeaevhgQDALEERLSLADRFGRTILFLRPDQEQYLRIVEhlAARRGLPIGRE-ELREAARR 404
Cdd:TIGR01243 599 R---------------------PDILDPALLRPGRFDRLILVPPPDEEARKEIFK--IHTRSMPLAEDvDLEELAEM 652
 
Name Accession Description Interval E-value
DUF815 pfam05673
Protein of unknown function (DUF815); This family consists of several bacterial proteins of ...
 182-428 3.83e-128

Protein of unknown function (DUF815); This family consists of several bacterial proteins of unknown function.


Pssm-ID: 428578 [Multi-domain]  Cd Length: 250  Bit Score: 370.33  E-value: 3.83e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 182 ASTWFLTWD---GAGLQPVEEPDLVDLDDLAGLEDQKAAVQENTEAFLRGGPGLNLLLYGPRGTGKSSLVRGLALRYGEA 258
Cdd:pfam05673   1 AAAPAFRWRrgeSGALEPVPHPDPVRLDDLVGIERQKEALIRNTRRFLAGLPANNVLLWGARGTGKSSLVKALLNEYADQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 259 GLRLVEVSRDRLGTLGDLYRTVRRYPQRFVLFLDDLTFEADDAEYRAFKSLLEGALERRPPNLVLYVTSNRRHMVPERWS 338
Cdd:pfam05673  81 GLRLIEVDKEDLGDLPDLVDLLRDRPYRFILFCDDLSFEEGESSYKALKSVLEGGLEARPDNVLIYATSNRRHLIPEYMS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 339 DRGSPEEAEVHGQDALEERLSLADRFGRTILFLRPDQEQYLRIVEHLAARRGLPIGREELREAARRWALWQNGLSGRTAR 418
Cdd:pfam05673 161 DNEGLVDGEIHPGDAVEEKLSLSDRFGLWLGFYPFDQDEYLAIVRGYAARLGLPLDEEELRREALQWALTRGGRSGRTAR 240

                         250
                  ....*....|
gi 1404710828 419 QFVDDLEAKL 428
Cdd:pfam05673 241 QFIDDLAGRL 250
Atu1564 COG2607
Predicted ATPase, AAA+ superfamily [General function prediction only];
156-433 1.94e-126

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 442019  Cd Length: 286  Bit Score: 367.50  E-value: 1.94e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 156 LAQAEDWADLVDELAA-------FHRAQGFgpvasTWFLTWDGAGLQPVEEPDLVDLDDLAGLEDQKAAVQENTEAFLRG 228
Cdd:COG2607     7 LARLERLLEALERLLPpppggpdFAAADAF-----RWRRRGGGGRLEPVPHPDPIRLDDLVGIERQKEILIRNTEQFLAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 229 GPGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVSRDRLGTLGDLYRTVRRYPQRFVLFLDDLTFEADDAEYRAFKS 308
Cdd:COG2607    82 LPANNVLLWGARGTGKSSLVKALLNEYADQGLRLIEVDKEDLADLPDIVELLRGRPERFIIFCDDLSFEEDETSYKALKA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 309 LLEGALERRPPNLVLYVTSNRRHMVPERWSDRGSPEEAEVHGQDALEERLSLADRFGRTILFLRPDQEQYLRIVEHLAAR 388
Cdd:COG2607   162 VLEGGLEARPDNVLIYATSNRRHLMPEYMSDNERPVDGEIHPGEAVEEKLSLSDRFGLWLGFYPPDQDEYLAIVRHLAAH 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1404710828 389 RGLPIGREELREAARRWALWQNGLSGRTARQFVDDLEAKLRSQRS 433
Cdd:COG2607   242 FGLDIDDEELRREALQWALTRGGRSGRVAWQFIDDLAGRLGLALD 286
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 118-423 2.07e-14

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 74.56  E-value: 2.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 118 ALLGGGVPHERLPTWAGRVDSEGDGPFVSPAFRAMARRLAQAEDWADLVDELAAFHRAQGFGPVASTWFLTWDGAGLQP- 196
Cdd:COG0464    67 ALLLLALLLLALLALLAALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEe 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 197 -VEEPDLVDLDDLAGLEDQKAAVQENTEAFLRG---------GPGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVS 266
Cdd:COG0464   147 eLLELREAILDDLGGLEEVKEELRELVALPLKRpelreeyglPPPRGLLLYGPPGTGKTLLARALA---GELGLPLIEVD 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 267 RDRL---------GTLGDLYRTVRRYpQRFVLFLDDL-------TFEADDAEYRAFKSLLEgALERRPPNLVLYVTSNRR 330
Cdd:COG0464   224 LSDLvskyvgeteKNLREVFDKARGL-APCVLFIDEAdalagkrGEVGDGVGRRVVNTLLT-EMEELRSDVVVIAATNRP 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 331 HMVPErwsdrgspeeaevhgqdaleerlSLADRFGRTILFLRPDQEQYLRIVEHLAARRGLPiGREELREAARRwalwQN 410
Cdd:COG0464   302 DLLDP-----------------------ALLRRFDEIIFFPLPDAEERLEIFRIHLRKRPLD-EDVDLEELAEA----TE 353

                         330
                  ....*....|...
gi 1404710828 411 GLSGRTARQFVDD 423
Cdd:COG0464   354 GLSGADIRNVVRR 366
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
205-423 5.36e-12

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 65.29  E-value: 5.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 205 LDDLAGLEDQKAAVQE------NTEAFLRGG--PGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSRDRLGT---- 272
Cdd:COG1223     1 LDDVVGQEEAKKKLKLiikelrRRENLRKFGlwPPRKILFYGPPGTGKTMLAEALA---GELKLPLLTVRLDSLIGsylg 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 273 -----LGDLYRTVRRYPQrfVLFLD-------DLTFEADDAEYRAFKSLLEGALERRPPNLVLYVTSNRRHMVperwsDR 340
Cdd:COG1223    78 etarnLRKLFDFARRAPC--VIFFDefdaiakDRGDQNDVGEVKRVVNALLQELDGLPSGSVVIAATNHPELL-----DS 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 341 gspeeaevhgqdaleerlSLADRFGRTILFLRPDQEQYLRIVEHLAARRGLPIGReELREAARRwalwQNGLSGRTARQF 420
Cdd:COG1223   151 ------------------ALWRRFDEVIEFPLPDKEERKEILELNLKKFPLPFEL-DLKKLAKK----LEGLSGADIEKV 207


                  ...
gi 1404710828 421 VDD 423
Cdd:COG1223   208 LKT 210
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 209-370 1.75e-09

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 56.00  E-value: 1.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 209 AGLEDQKAAVQEnteaFLRGGPGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEV--SRDRLGTLGDLYRTV------ 280
Cdd:cd00009     1 VGQEEAIEALRE----ALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLnaSDLLEGLVVAELFGHflvrll 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 281 ---RRYPQRFVLFLDD---LTFEADDAEYRAFKSLLEGALERRppNLVLYVTSNRRhmvperwsdrgspeeaevhgqDAL 354
Cdd:cd00009    77 felAEKAKPGVLFIDEidsLSRGAQNALLRVLETLNDLRIDRE--NVRVIGATNRP---------------------LLG 133

                         170
                  ....*....|....*.
gi 1404710828 355 EERLSLADRFGRTILF 370
Cdd:cd00009   134 DLDRALYDRLDIRIVI 149
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 151-434 2.90e-08

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 55.01  E-value: 2.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 151 AMARRLAQAEDWADLVDELA-AFHRAQGFGPVASTWFLTWDgaglqPVEEPDlVDLDDLAGLEDQKAAVQE-------NT 222
Cdd:COG1222    28 ELALLLQPVKALELLEEAPAlLLNDANLTQKRLGTPRGTAV-----PAESPD-VTFDDIGGLDEQIEEIREavelplkNP 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 223 EAFLRGG--PGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSRDRLGT--LGDLYRTVR------RYPQRFVLFLD 292
Cdd:COG1222   102 ELFRKYGiePPKGVLLYGPPGTGKTLLAKAVA---GELGAPFIRVRGSELVSkyIGEGARNVRevfelaREKAPSIIFID 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 293 DL-------TFEADDAEYR----AFKSLLEGaLERRPPNLVLYVTsNRrhmvperwsdrgspeeaevhgQDALEERLSLA 361
Cdd:COG1222   179 EIdaiaarrTDDGTSGEVQrtvnQLLAELDG-FESRGDVLIIAAT-NR---------------------PDLLDPALLRP 235

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1404710828 362 DRFGRTILFLRPDQEQYLRIVEHLAarRGLPIGREE-LREAARRWAlwqnGLSGRTARQFVDDL-EAKLRSQRSQ 434
Cdd:COG1222   236 GRFDRVIEVPLPDEEAREEILKIHL--RDMPLADDVdLDKLAKLTE----GFSGADLKAIVTEAgMFAIREGRDT 304
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 234-335 1.91e-07

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 49.90  E-value: 1.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 234 LLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSRDRL--GTLGDLYRTVRRYPQRF------VLFLDDL-------TFEA 298
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVA---KELGAPFIEISGSELvsKYVGESEKRLRELFEAAkklapcVIFIDEIdalagsrGSGG 77

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1404710828 299 DDAEYRAFKSLLE--GALERRPPNLVLYVTSNRRHMVPE 335
Cdd:pfam00004  78 DSESRRVVNQLLTelDGFTSSNSKVIVIAATNRPDKLDP 116
PRK04195 PRK04195
replication factor C large subunit; Provisional
 205-280 3.62e-06

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 49.15  E-value: 3.62e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1404710828 205 LDDLAGLEDQKAAVQENTEAFLRGGPGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEV--SRDRlgTLGDLYRTV 280
Cdd:PRK04195   13 LSDVVGNEKAKEQLREWIESWLKGKPKKALLLYGPPGVGKTSLAHALA---NDYGWEVIELnaSDQR--TADVIERVA 85
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 230-331 8.23e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 45.44  E-value: 8.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828  230 PGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVS----------------RDRLGTLGDLYRTVR------RYPQRF 287
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDgedileevldqllliiVGGKKASGSGELRLRlalalaRKLKPD 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1404710828  288 VLFLDDLTFEADD---AEYRAFKSLLEGALERRPPNLVLYVTSNRRH 331
Cdd:smart00382  81 VLILDEITSLLDAeqeALLLLLEELRLLLLLKSEKNLTVILTTNDEK 127
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 214-293 5.10e-05

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 43.43  E-value: 5.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 214 QKAAVQENTEAFLRGGPGL--------NLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSRDRLGT--LGDLYRTVRRY 283
Cdd:cd19481     1 LKASLREAVEAPRRGSRLRryglglpkGILLYGPPGTGKTLLAKALA---GELGLPLIVVKLSSLLSkyVGESEKNLRKI 77

                          90
                  ....*....|....*.
gi 1404710828 284 PQRF------VLFLDD 293
Cdd:cd19481    78 FERArrlapcILFIDE 93
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 208-319 1.27e-04

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 42.49  E-value: 1.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 208 LAGLEDQKAAVQENTEAFLRGGPGlNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVSRDRLGTLGDLYRTVRRYPqrf 287
Cdd:pfam13191   2 LVGREEELEQLLDALDRVRSGRPP-SVLLTGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSPLLEALTREG--- 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1404710828 288 vlFLDDLTFEADDAEYRAFKSLLEGALERRPP 319
Cdd:pfam13191  78 --LLRQLLDELESSLLEAWRAALLEALAPVPE 107
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
 235-294 3.65e-04

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 40.80  E-value: 3.65e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1404710828 235 LLYGPRGTGKSSLVRGLA--LRYGEAGLRLVEVSRDRlgtlGDLYRTVRRYPQRFVLFLDDL 294
Cdd:cd19510    27 LLYGPPGTGKSSFIAALAgeLDYDICDLNLSEVVLTD----DRLNHLLNTAPKQSIILLEDI 84
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
 203-294 4.80e-04

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 40.62  E-value: 4.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 203 VDLDDLAGLEDQKAAVQENT------EAFLRGG--PGLNLLLYGPRGTGKSSLVRGLALrygEAGLRLVEVSRDRLGT-- 272
Cdd:cd19521     4 VKWEDVAGLEGAKEALKEAVilpvkfPHLFTGNrkPWSGILLYGPPGTGKSYLAKAVAT---EANSTFFSVSSSDLVSkw 80

                          90       100
                  ....*....|....*....|....*...
gi 1404710828 273 LGDLYRTVR------RYPQRFVLFLDDL 294
Cdd:cd19521    81 MGESEKLVKqlfamaRENKPSIIFIDEV 108
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 197-404 5.04e-04

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 42.59  E-value: 5.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 197 VEEPDlVDLDDLAGLEDQKAAVQENTE-------AFLRGG--PGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSR 267
Cdd:TIGR01243 445 VEVPN-VRWSDIGGLEEVKQELREAVEwplkhpeIFEKMGirPPKGVLLFGPPGTGKTLLAKAVA---TESGANFIAVRG 520

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 268 DRLGT--LGDLYRTVRRYPQRF------VLFLDDL--------TFEADDAEYRAFKSLL---EGALErrPPNLVLYVTSN 328
Cdd:TIGR01243 521 PEILSkwVGESEKAIREIFRKArqaapaIIFFDEIdaiapargARFDTSVTDRIVNQLLtemDGIQE--LSNVVVIAATN 598

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1404710828 329 RrhmvperwsdrgspeeaevhgQDALEERLSLADRFGRTILFLRPDQEQYLRIVEhlAARRGLPIGRE-ELREAARR 404
Cdd:TIGR01243 599 R---------------------PDILDPALLRPGRFDRLILVPPPDEEARKEIFK--IHTRSMPLAEDvDLEELAEM 652
PRK06526 PRK06526
transposase; Provisional
 146-329 5.22e-04

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 41.39  E-value: 5.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 146 SPAFRAMARRL---AQAEDW-------ADLVDELAAFHRAQGFGPVASTWFltwdgAGLQPVEEpdlVDLDDLAGLEDQK 215
Cdd:PRK06526   14 APTLAGAVERLaerARAESWsheeflaACLQREVAARESHGGEGRIRAARF-----PARKSLEE---FDFDHQRSLKRDT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 216 AAvQENTEAFLRGGPglNLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVSR----DRL------GTLGDLYRTVRRYPQ 285
Cdd:PRK06526   86 IA-HLGTLDFVTGKE--NVVFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAaqwvARLaaahhaGRLQAELVKLGRYPL 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1404710828 286 RFVLFLDDLTFEADDAEYraFKSLLEGALERRPpnlvLYVTSNR 329
Cdd:PRK06526  163 LIVDEVGYIPFEPEAANL--FFQLVSSRYERAS----LIVTSNK 200
AAA_22 pfam13401
AAA domain;
226-325 6.34e-04

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 39.63  E-value: 6.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 226 LRGGPGLnLLLYGPRGTGKSSLVRGLALRYGEAGLRLVEVSRDRLGTLGDLYRTVRRypqrfvlFLDDLTFEADDAEyrA 305
Cdd:pfam13401   1 IRFGAGI-LVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPKDLLRALLR-------ALGLPLSGRLSKE--E 70

                          90       100
                  ....*....|....*....|
gi 1404710828 306 FKSLLEGALERRPPNLVLYV 325
Cdd:pfam13401  71 LLAALQQLLLALAVAVVLII 90
PRK08181 PRK08181
transposase; Validated
 229-329 8.19e-04

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 41.07  E-value: 8.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 229 GPGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRL-----------VEVSRDRLGtlgdLYRTVRRYPQRFVLFLDDLTF- 296
Cdd:PRK08181  104 AKGANLLLFGPPGGGKSHLAAAIGLALIENGWRVlftrttdlvqkLQVARRELQ----LESAIAKLDKFDLLILDDLAYv 179

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1404710828 297 EADDAEYRAFKSLLEGALERRPpnlvLYVTSNR 329
Cdd:PRK08181  180 TKDQAETSVLFELISARYERRS----ILITANQ 208
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 207-294 8.67e-04

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 39.97  E-value: 8.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 207 DLAGLEDQKAAVQE-------NTEAFLRGG--PGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVS-----RDRLG- 271
Cdd:cd19503     1 DIGGLDEQIASLKElielplkYPELFRALGlkPPRGVLLHGPPGTGKTLLARAVA---NEAGANFLSISgpsivSKYLGe 77

                          90       100
                  ....*....|....*....|....*.
gi 1404710828 272 ---TLGDLYRTVRRYpQRFVLFLDDL 294
Cdd:cd19503    78 sekNLREIFEEARSH-APSIIFIDEI 102
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 197-252 1.91e-03

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 40.20  E-value: 1.91e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1404710828 197 VEEPDlVDLDDLAGLEDQKAAVQE-------NTEAFLRGG--PGLNLLLYGPRGTGKSSLVRGLA 252
Cdd:PRK03992  123 IESPN-VTYEDIGGLEEQIREVREavelplkKPELFEEVGiePPKGVLLYGPPGTGKTLLAKAVA 186
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 208-252 2.18e-03

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 38.87  E-value: 2.18e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1404710828 208 LAGLEDQKAAVQENT-------EAFlRGGPGL--NLLLYGPRGTGKSSLVRGLA 252
Cdd:cd19509     1 IAGLDDAKEALKEAVilpslrpDLF-PGLRGPprGILLYGPPGTGKTLLARAVA 53
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
 203-294 2.58e-03

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 38.75  E-value: 2.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 203 VDLDDLAGLEDQKAAVQE------NTEAFLRGGPGL--NLLLYGPRGTGKSSLVRGLAlryGEAGL--------RLVEV- 265
Cdd:cd19501     1 VTFKDVAGCEEAKEELKEvveflkNPEKFTKLGAKIpkGVLLVGPPGTGKTLLAKAVA---GEAGVpffsisgsDFVEMf 77

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1404710828 266 -----SRDRlgtlgDLYRTVRRYPqRFVLFLDDL 294
Cdd:cd19501    78 vgvgaSRVR-----DLFEQAKKNA-PCIVFIDEI 105
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 219-294 2.94e-03

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 38.42  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1404710828 219 QENTEAFLRGG--PGLNLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVSRDRLGT--LGDLYRTVRRYPQRF------V 288
Cdd:cd19511    13 LKHPDAFKRLGirPPKGVLLYGPPGCGKTLLAKALA---SEAGLNFISVKGPELFSkyVGESERAVREIFQKArqaapcI 89


                  ....*.
gi 1404710828 289 LFLDDL 294
Cdd:cd19511    90 IFFDEI 95
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
 207-262 3.28e-03

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 38.33  E-value: 3.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1404710828 207 DLAGLEDQKAAVQEN-------TEAFlrggPGL-----NLLLYGPRGTGKSSLVRGLALRYGEAGLRL 262
Cdd:cd19523     1 DIAGLGALKAAIKEEvlwpllrPDAF----SGLlrlprSILLFGPRGTGKTLLGRCLASQLGATFLRL 64
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
206-249 3.49e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 39.45  E-value: 3.49e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1404710828 206 DDLAGLEDQKAAVQENTEAFLRGGPGLNLLLYGPRGTGKSSLVR 249
Cdd:COG1474    26 DRLPHREEEIEELASALRPALRGERPSNVLIYGPTGTGKTAVAK 69
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
 194-263 4.14e-03

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 39.36  E-value: 4.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1404710828 194 LQPVEEPDlVDLDDLAGLEDQKAAVQENTEAFLRGG---------PGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLV 263
Cdd:PTZ00454  134 LQMSEKPD-VTYSDIGGLDIQKQEIREAVELPLTCPelyeqigidPPRGVLLYGPPGTGKTMLAKAVAHHTTATFIRVV 211
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 206-263 4.61e-03

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 37.70  E-value: 4.61e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1404710828 206 DDLAGLEDQKAAVQE-------NTEAFLRGG--PGLNLLLYGPRGTGKSSLVRGLALRYGEAGLRLV 263
Cdd:cd19502     3 EDIGGLDEQIREIREvvelplkHPELFEELGiePPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVV 69
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 233-292 5.28e-03

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 38.91  E-value: 5.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1404710828 233 NLLLYGPRGTGKSSLVRGLAlryGEAGLRLVEVS---------RDRLgtlgDLYRTVRRYPQRFVLFLD 292
Cdd:PRK13342   38 SMILWGPPGTGKTTLARIIA---GATDAPFEALSavtsgvkdlREVI----EEARQRRSAGRRTILFID 99
ABC_SMC5_euk cd03277
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ...
 226-253 6.65e-03

ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213244 [Multi-domain]  Cd Length: 213  Bit Score: 37.96  E-value: 6.65e-03
                          10        20
                  ....*....|....*....|....*...
gi 1404710828 226 LRGGPGLNLLLyGPRGTGKSSLVRGLAL 253
Cdd:cd03277    19 FRPGPSLNMII-GPNGSGKSSIVCAICL 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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