![](files/infoQ.gif)
nitrogenase iron protein NifH, partial [uncultured Gammaproteobacteria bacterium]
P-loop NTPase family protein( domain architecture ID 1562424)
P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | |||
P-loop_NTPase super family | cl38936 | P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ... |
1-109 | 3.05e-67 | |||
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families. The actual alignment was detected with superfamily member TIGR01287: Pssm-ID: 476819 Cd Length: 275 Bit Score: 203.00 E-value: 3.05e-67
|
|||||||
Name | Accession | Description | Interval | E-value | |||
nifH | TIGR01287 | nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ... |
1-109 | 3.05e-67 | |||
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation] Pssm-ID: 273538 Cd Length: 275 Bit Score: 203.00 E-value: 3.05e-67
|
|||||||
NifH | cd02040 | nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ... |
1-109 | 5.57e-62 | |||
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia. Pssm-ID: 349759 Cd Length: 265 Bit Score: 189.26 E-value: 5.57e-62
|
|||||||
nifH | PRK13233 | nitrogenase iron protein; |
1-109 | 5.22e-55 | |||
nitrogenase iron protein; Pssm-ID: 183905 Cd Length: 275 Bit Score: 171.93 E-value: 5.22e-55
|
|||||||
Fer4_NifH | pfam00142 | 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; |
1-109 | 1.34e-54 | |||
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; Pssm-ID: 395090 Cd Length: 271 Bit Score: 170.70 E-value: 1.34e-54
|
|||||||
F430_CfbC | NF033200 | Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ... |
1-109 | 3.23e-47 | |||
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs. Pssm-ID: 380202 Cd Length: 260 Bit Score: 151.57 E-value: 3.23e-47
|
|||||||
Name | Accession | Description | Interval | E-value | |||
nifH | TIGR01287 | nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ... |
1-109 | 3.05e-67 | |||
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation] Pssm-ID: 273538 Cd Length: 275 Bit Score: 203.00 E-value: 3.05e-67
|
|||||||
NifH | cd02040 | nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ... |
1-109 | 5.57e-62 | |||
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia. Pssm-ID: 349759 Cd Length: 265 Bit Score: 189.26 E-value: 5.57e-62
|
|||||||
nifH | PRK13233 | nitrogenase iron protein; |
1-109 | 5.22e-55 | |||
nitrogenase iron protein; Pssm-ID: 183905 Cd Length: 275 Bit Score: 171.93 E-value: 5.22e-55
|
|||||||
Fer4_NifH | pfam00142 | 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; |
1-109 | 1.34e-54 | |||
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; Pssm-ID: 395090 Cd Length: 271 Bit Score: 170.70 E-value: 1.34e-54
|
|||||||
NifH-like | cd02117 | NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) ... |
1-109 | 1.56e-49 | |||
NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) of the protochlorophyllide reductase, and the BchX subunit of the Chlorophyllide reductase. Members of this family use energy from ATP hydrolysis and transfer electrons through a Fe4-S4 cluster to other subunit for substrate reduction Pssm-ID: 349761 Cd Length: 266 Bit Score: 157.91 E-value: 1.56e-49
|
|||||||
F430_CfbC | NF033200 | Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ... |
1-109 | 3.23e-47 | |||
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs. Pssm-ID: 380202 Cd Length: 260 Bit Score: 151.57 E-value: 3.23e-47
|
|||||||
PRK13231 | PRK13231 | nitrogenase reductase-like protein; Reviewed |
28-109 | 3.61e-34 | |||
nitrogenase reductase-like protein; Reviewed Pssm-ID: 183904 Cd Length: 264 Bit Score: 118.36 E-value: 3.61e-34
|
|||||||
PRK13230 | PRK13230 | nitrogenase reductase-like protein; Reviewed |
1-109 | 2.76e-33 | |||
nitrogenase reductase-like protein; Reviewed Pssm-ID: 183903 Cd Length: 279 Bit Score: 116.41 E-value: 2.76e-33
|
|||||||
Bchl-like | cd02032 | L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. ... |
25-107 | 5.64e-19 | |||
L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. Protochlorophyllide reductase catalyzes the reductive formation of chlorophyllide from protochlorophyllide during biosynthesis of chlorophylls and bacteriochlorophylls. Three genes, bchL, bchN and bchB, are involved in light-independent protochlorophyllide reduction in bacteriochlorophyll biosynthesis. In cyanobacteria, algae, and gymnosperms, three similar genes, chlL, chlN and chlB are involved in protochlorophyllide reduction during chlorophylls biosynthesis. BchL/chlL, bchN/chlN and bchB/chlB exhibit significant sequence similarity to the nifH, nifD and nifK subunits of nitrogenase, respectively. Nitrogenase catalyzes the reductive formation of ammonia from dinitrogen. Pssm-ID: 349752 Cd Length: 267 Bit Score: 78.88 E-value: 5.64e-19
|
|||||||
chlL | PRK13185 | protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional |
25-109 | 1.47e-17 | |||
protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional Pssm-ID: 237293 Cd Length: 270 Bit Score: 75.00 E-value: 1.47e-17
|
|||||||
BchX | cd02033 | X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls ... |
1-109 | 5.69e-15 | |||
X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls into bacteriochlorophylls by reducing the chlorin B-ring. This family contains the X subunit of this three-subunit enzyme. Sequence and structure similarity between bchX, protochlorophyllide reductase L subunit (bchL and chlL) and nitrogenase Fe protein (nifH gene) suggest their functional similarity. Members of the BchX family serve as the unique electron donors to their respective catalytic subunits (bchN-bchB, bchY-bchZ and nitrogenase component 1). Mechanistically, they hydrolyze ATP and transfer electrons through a Fe4-S4 cluster. Pssm-ID: 349753 Cd Length: 329 Bit Score: 68.70 E-value: 5.69e-15
|
|||||||
chlL | CHL00072 | photochlorophyllide reductase subunit L |
25-96 | 5.72e-14 | |||
photochlorophyllide reductase subunit L Pssm-ID: 177011 Cd Length: 290 Bit Score: 65.53 E-value: 5.72e-14
|
|||||||
Blast search parameters | ||||
|