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Conserved domains on  [gi|1390256476|gb|AWL10113|]
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hypothetical protein HME7025_02266 [Aquirufa nivalisilvae]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18640064)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 334-436 4.73e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.60  E-value: 4.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  334 FSLFKSGQYQESEILLSKLInKETLSDSLSQLVHYQIGMSQFHLKNYDAAGTSLEKAILINWDKSLSEDAYFNQLVALEN 413
Cdd:COG1729      1 KALLKAGDYDEAIAAFKAFL-KRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLE 79

                           90       100
                   ....*....|....*....|...
gi 1390256476  414 RGSFDVLLSKTKDFLRQYPRSKH 436
Cdd:COG1729     80 LGDYDKARATLEELIKKYPDSEA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 134-356 3.36e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 3.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  134 EIGSFLYKAGEYQDAIQYIEQRVSI--LDPEIRFQLAICYLQVGLNTKALSLFELLSNDDNESVAYaaSYYSGLLKLNLK 211
Cdd:COG2956     81 ELAQDYLKAGLLDRAEELLEKLLELdpDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHA--YCELAELYLEQG 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  212 QYSAAIFDLKKAdeapfqLAQVPlsDSVWVRIkrqiptMITQAYYQMGpdKYADLIAYAEPIIlndKRAVEKSDIARLLG 291
Cdd:COG2956    159 DYDEAIEALEKA------LKLDP--DCARALL------LLAELYLEQG--DYEEAIAALERAL---EQDPDYLPALPRLA 219

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390256476  292 DIYFNQGKFSKSAEIYAQYLLINESKRAVfqsntegipLKQAFSLFKSGQYQESEILLSKLINKE 356
Cdd:COG2956    220 ELYEKLGDPEEALELLRKALELDPSDDLL---------LALADLLERKEGLEAALALLERQLRRH 275
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 835-946 4.36e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 4.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  835 MELYQSKRWDVARITLLEFQKIYPNSSNNNVLLKNLATSSDSLHDYPKAIEFYQQIVNKKDkfKSAEVISAAKRTAELAL 914
Cdd:COG1729      1 KALLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYP--DSPKAPDALLKLGLSYL 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1390256476  915 ENNQMNVAISSYQ-FIKSYTKvSRYQKLANENL 946
Cdd:COG1729     79 ELGDYDKARATLEeLIKKYPD-SEAAKEARARL 110
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 837-1107 7.15e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 7.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  837 LYQSKRWDVARITLLEFQKIYPNSSNNNVLLKNLATSSDslhDYPKAIEFYQQIVNKKDKFKSAEVisaakRTAELALEN 916
Cdd:COG2956     18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG---EYDRAIRIHQKLLERDPDRAEALL-----ELAQDYLKA 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  917 NQMNVAISSYQFIksyTKVSRYQKLANENLVNIYLQSKQLDslyNLTSTWDDLYEVDEKNEFYQKYL-QISEEAQQTELV 995
Cdd:COG2956     90 GLLDRAEELLEKL---LELDPDDAEALRLLAEIYEQEGDWE---KAIEVLERLLKLGPENAHAYCELaELYLEQGDYDEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  996 KKWLQK-ISINNHLspvvqqivigAEAELKYAQLLFQEKKHIELDELLDKTLirkivptniRTKKTYFRGLLLYADNLMA 1074
Cdd:COG2956    164 IEALEKaLKLDPDC----------ARALLLLAELYLEQGDYEEAIAALERAL---------EQDPDYLPALPRLAELYEK 224

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1390256476 1075 LDQKDKAMGYYTALAQNMTKENDVRNLAKSRLK 1107
Cdd:COG2956    225 LGDPEEALELLRKALELDPSDDLLLALADLLER 257
 
Name Accession Description Interval E-value
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 334-436 4.73e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.60  E-value: 4.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  334 FSLFKSGQYQESEILLSKLInKETLSDSLSQLVHYQIGMSQFHLKNYDAAGTSLEKAILINWDKSLSEDAYFNQLVALEN 413
Cdd:COG1729      1 KALLKAGDYDEAIAAFKAFL-KRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLE 79

                           90       100
                   ....*....|....*....|...
gi 1390256476  414 RGSFDVLLSKTKDFLRQYPRSKH 436
Cdd:COG1729     80 LGDYDKARATLEELIKKYPDSEA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 134-356 3.36e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 3.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  134 EIGSFLYKAGEYQDAIQYIEQRVSI--LDPEIRFQLAICYLQVGLNTKALSLFELLSNDDNESVAYaaSYYSGLLKLNLK 211
Cdd:COG2956     81 ELAQDYLKAGLLDRAEELLEKLLELdpDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHA--YCELAELYLEQG 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  212 QYSAAIFDLKKAdeapfqLAQVPlsDSVWVRIkrqiptMITQAYYQMGpdKYADLIAYAEPIIlndKRAVEKSDIARLLG 291
Cdd:COG2956    159 DYDEAIEALEKA------LKLDP--DCARALL------LLAELYLEQG--DYEEAIAALERAL---EQDPDYLPALPRLA 219

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390256476  292 DIYFNQGKFSKSAEIYAQYLLINESKRAVfqsntegipLKQAFSLFKSGQYQESEILLSKLINKE 356
Cdd:COG2956    220 ELYEKLGDPEEALELLRKALELDPSDDLL---------LALADLLERKEGLEAALALLERQLRRH 275
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 835-946 4.36e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 4.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  835 MELYQSKRWDVARITLLEFQKIYPNSSNNNVLLKNLATSSDSLHDYPKAIEFYQQIVNKKDkfKSAEVISAAKRTAELAL 914
Cdd:COG1729      1 KALLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYP--DSPKAPDALLKLGLSYL 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1390256476  915 ENNQMNVAISSYQ-FIKSYTKvSRYQKLANENL 946
Cdd:COG1729     79 ELGDYDKARATLEeLIKKYPD-SEAAKEARARL 110
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 837-1107 7.15e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 7.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  837 LYQSKRWDVARITLLEFQKIYPNSSNNNVLLKNLATSSDslhDYPKAIEFYQQIVNKKDKFKSAEVisaakRTAELALEN 916
Cdd:COG2956     18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG---EYDRAIRIHQKLLERDPDRAEALL-----ELAQDYLKA 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  917 NQMNVAISSYQFIksyTKVSRYQKLANENLVNIYLQSKQLDslyNLTSTWDDLYEVDEKNEFYQKYL-QISEEAQQTELV 995
Cdd:COG2956     90 GLLDRAEELLEKL---LELDPDDAEALRLLAEIYEQEGDWE---KAIEVLERLLKLGPENAHAYCELaELYLEQGDYDEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  996 KKWLQK-ISINNHLspvvqqivigAEAELKYAQLLFQEKKHIELDELLDKTLirkivptniRTKKTYFRGLLLYADNLMA 1074
Cdd:COG2956    164 IEALEKaLKLDPDC----------ARALLLLAELYLEQGDYEEAIAALERAL---------EQDPDYLPALPRLAELYEK 224

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1390256476 1075 LDQKDKAMGYYTALAQNMTKENDVRNLAKSRLK 1107
Cdd:COG2956    225 LGDPEEALELLRKALELDPSDDLLLALADLLER 257
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 134-394 1.45e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  134 EIGSFLYKAGEYQDAIQYIEQRVSI-LDPE-IRFQLAICYLQVGLNTKALSLFELLSNDDNESVAyAASYYSGLLKLNLK 211
Cdd:TIGR02917   61 LLGKIYLALGDYAAAEKELRKALSLgYPKNqVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAA-ELLALRGLAYLGLG 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  212 QYSAAifdlkkadEAPFQLAQVPLSDSvwvrikrqIPTMITQAYYQMGPDKYADLIAYAEPIILNDKRAVeksDIARLLG 291
Cdd:TIGR02917  140 QLELA--------QKSYEQALAIDPRS--------LYAKLGLAQLALAENRFDEARALIDEVLTADPGNV---DALLLKG 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  292 DIYFNQGKFSKSAEIYAQYLLINESKRAVFqsntegipLKQAFSLFKSGQYQESEILLsklinkETLSDSLSQ--LVHYQ 369
Cdd:TIGR02917  201 DLLLSLGNIELALAAYRKAIALRPNNIAVL--------LALATILIEAGEFEEAEKHA------DALLKKAPNspLAHYL 266

                          250       260
                   ....*....|....*....|....*
gi 1390256476  370 IGMSQFHLKNYDAAGTSLEKAILIN 394
Cdd:TIGR02917  267 KALVDFQKKNYEDARETLQDALKSA 291
TPR_19 pfam14559
Tetratricopeptide repeat;
142-199 6.78e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.02  E-value: 6.78e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  142 AGEYQDAIQYIEQRVSIL--DPEIRFQLAICYLQVGLNTKALSLFELLSNDDNESVAYAA 199
Cdd:pfam14559    1 EGDYAEALELLEQALAEDpdNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
 
Name Accession Description Interval E-value
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 334-436 4.73e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.60  E-value: 4.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  334 FSLFKSGQYQESEILLSKLInKETLSDSLSQLVHYQIGMSQFHLKNYDAAGTSLEKAILINWDKSLSEDAYFNQLVALEN 413
Cdd:COG1729      1 KALLKAGDYDEAIAAFKAFL-KRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLE 79

                           90       100
                   ....*....|....*....|...
gi 1390256476  414 RGSFDVLLSKTKDFLRQYPRSKH 436
Cdd:COG1729     80 LGDYDKARATLEELIKKYPDSEA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 134-356 3.36e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 3.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  134 EIGSFLYKAGEYQDAIQYIEQRVSI--LDPEIRFQLAICYLQVGLNTKALSLFELLSNDDNESVAYaaSYYSGLLKLNLK 211
Cdd:COG2956     81 ELAQDYLKAGLLDRAEELLEKLLELdpDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHA--YCELAELYLEQG 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  212 QYSAAIFDLKKAdeapfqLAQVPlsDSVWVRIkrqiptMITQAYYQMGpdKYADLIAYAEPIIlndKRAVEKSDIARLLG 291
Cdd:COG2956    159 DYDEAIEALEKA------LKLDP--DCARALL------LLAELYLEQG--DYEEAIAALERAL---EQDPDYLPALPRLA 219

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390256476  292 DIYFNQGKFSKSAEIYAQYLLINESKRAVfqsntegipLKQAFSLFKSGQYQESEILLSKLINKE 356
Cdd:COG2956    220 ELYEKLGDPEEALELLRKALELDPSDDLL---------LALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 110-391 1.27e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  110 RAKVAVERFIANHPSSLKTSIlvkEIGSFLYKAGEYQDAIQYIEQRVSILD--PEIRFQLAICYLQVGLNTKALSLFE-L 186
Cdd:COG2956     26 KAIDLLEEALELDPETVEAHL---ALGNLYRRRGEYDRAIRIHQKLLERDPdrAEALLELAQDYLKAGLLDRAEELLEkL 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  187 LSNDDNESVAYaasYYSGLLKLNLKQYSAAIFDLKKADEAPFQLAQVPLsdsvwvrikrqiptMITQAYYQMGpdKYADL 266
Cdd:COG2956    103 LELDPDDAEAL---RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYC--------------ELAELYLEQG--DYDEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  267 IAYAEPIILNDKRAVEksdIARLLGDIYFNQGKFSKSAEIYAQYLLINESKRAVFQsntegiPLKQAFSlfKSGQYQESE 346
Cdd:COG2956    164 IEALEKALKLDPDCAR---ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP------RLAELYE--KLGDPEEAL 232

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1390256476  347 ILLSKLINKETLSDSLSQLVHYQIgmsqfHLKNYDAAGTSLEKAI 391
Cdd:COG2956    233 ELLRKALELDPSDDLLLALADLLE-----RKEGLEAALALLERQL 272
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 110-247 1.43e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 1.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  110 RAKVAVERFIANHPSSLKTSILvkeIGSFLYKAGEYQDAIQYIEQRVSIL--DPEIRFQLAICYLQVGLNTKALSLFE-L 186
Cdd:COG4235      1 EAIARLRQALAANPNDAEGWLL---LGRAYLRLGRYDEALAAYEKALRLDpdNADALLDLAEALLAAGDTEEAEELLErA 77

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390256476  187 LSNDDNESVAYaasYYSGLLKLNLKQYSAAIFDLKKAdeapfqLAQVPlSDSVWVRIKRQI 247
Cdd:COG4235     78 LALDPDNPEAL---YLLGLAAFQQGDYAEAIAAWQKL------LALLP-ADAPARLLEASI 128
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 835-946 4.36e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 4.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  835 MELYQSKRWDVARITLLEFQKIYPNSSNNNVLLKNLATSSDSLHDYPKAIEFYQQIVNKKDkfKSAEVISAAKRTAELAL 914
Cdd:COG1729      1 KALLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYP--DSPKAPDALLKLGLSYL 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1390256476  915 ENNQMNVAISSYQ-FIKSYTKvSRYQKLANENL 946
Cdd:COG1729     79 ELGDYDKARATLEeLIKKYPD-SEAAKEARARL 110
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 139-222 5.45e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 5.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  139 LYKAGEYQDAIQYIEQRV-----SILDPEIRFQLAICYLQVGLNTKALSLFELLSNDDNESVAYA-ASYYSGLLKLNLKQ 212
Cdd:COG1729      3 LLKAGDYDEAIAAFKAFLkrypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPdALLKLGLSYLELGD 82

                           90
                   ....*....|
gi 1390256476  213 YSAAIFDLKK 222
Cdd:COG1729     83 YDKARATLEE 92
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 837-1107 7.15e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 7.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  837 LYQSKRWDVARITLLEFQKIYPNSSNNNVLLKNLATSSDslhDYPKAIEFYQQIVNKKDKFKSAEVisaakRTAELALEN 916
Cdd:COG2956     18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG---EYDRAIRIHQKLLERDPDRAEALL-----ELAQDYLKA 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  917 NQMNVAISSYQFIksyTKVSRYQKLANENLVNIYLQSKQLDslyNLTSTWDDLYEVDEKNEFYQKYL-QISEEAQQTELV 995
Cdd:COG2956     90 GLLDRAEELLEKL---LELDPDDAEALRLLAEIYEQEGDWE---KAIEVLERLLKLGPENAHAYCELaELYLEQGDYDEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  996 KKWLQK-ISINNHLspvvqqivigAEAELKYAQLLFQEKKHIELDELLDKTLirkivptniRTKKTYFRGLLLYADNLMA 1074
Cdd:COG2956    164 IEALEKaLKLDPDC----------ARALLLLAELYLEQGDYEEAIAALERAL---------EQDPDYLPALPRLAELYEK 224

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1390256476 1075 LDQKDKAMGYYTALAQNMTKENDVRNLAKSRLK 1107
Cdd:COG2956    225 LGDPEEALELLRKALELDPSDDLLLALADLLER 257
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
135-231 9.07e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 42.30  E-value: 9.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  135 IGSFLYKAGEYQDAIQYIEQRVSI--LDPEIRFQLAICYLQVGLNTKALSLFE-LLSNDDNESVAYaasYYSGLLKLNLK 211
Cdd:COG0457     82 LGLALQALGRYEEALEDYDKALELdpDDAEALYNLGLALLELGRYDEAIEAYErALELDPDDADAL---YNLGIALEKLG 158

                           90       100
                   ....*....|....*....|
gi 1390256476  212 QYSAAIFDLKKADEAPFQLA 231
Cdd:COG0457    159 RYEEALELLEKLEAAALAAL 178
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
135-223 9.83e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 42.30  E-value: 9.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  135 IGSFLYKAGEYQDAIQYIEQRVSIL--DPEIRFQLAICYLQVGLNTKALSLFE-LLSNDDNESVAYaasYYSGLLKLNLK 211
Cdd:COG0457     48 LGLAYLRLGRYEEALADYEQALELDpdDAEALNNLGLALQALGRYEEALEDYDkALELDPDDAEAL---YNLGLALLELG 124

                           90
                   ....*....|..
gi 1390256476  212 QYSAAIFDLKKA 223
Cdd:COG0457    125 RYDEAIEAYERA 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
135-311 1.31e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.92  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  135 IGSFLYKAGEYQDAIQYIEQRVSI--LDPEIRFQLAICYLQVGLNTKALSLFE-LLSNDDNESVAYaasYYSGLLKLNLK 211
Cdd:COG0457     14 LGLAYRRLGRYEEAIEDYEKALELdpDDAEALYNLGLAYLRLGRYEEALADYEqALELDPDDAEAL---NNLGLALQALG 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  212 QYSAAIFDLKKAdeapfqLAQVPLSDSVWVRIKRqiptmitqAYYQMGpdKYADLIAYAEPIILNDKRAVEksdIARLLG 291
Cdd:COG0457     91 RYEEALEDYDKA------LELDPDDAEALYNLGL--------ALLELG--RYDEAIEAYERALELDPDDAD---ALYNLG 151

                          170       180
                   ....*....|....*....|
gi 1390256476  292 DIYFNQGKFSKSAEIYAQYL 311
Cdd:COG0457    152 IALEKLGRYEEALELLEKLE 171
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 107-226 1.34e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  107 NTTRAKVAVERFIANHPSSLKTSILvkeIGSFLYKAGEYQDAIQYIEQRVSIL--DPEIRFQLAICYLQVGLNTKALSLF 184
Cdd:COG4783     19 DYDEAEALLEKALELDPDNPEAFAL---LGEILLQLGDLDEAIVLLHEALELDpdEPEARLNLGLALLKAGDYDEALALL 95

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1390256476  185 ELLSNDDNESvaYAASYYSGLLKLNLKQYSAAIFDLKKADEA 226
Cdd:COG4783     96 EKALKLDPEH--PEAYLRLARAYRALGRPDEAIAALEKALEL 135
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 134-394 1.45e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  134 EIGSFLYKAGEYQDAIQYIEQRVSI-LDPE-IRFQLAICYLQVGLNTKALSLFELLSNDDNESVAyAASYYSGLLKLNLK 211
Cdd:TIGR02917   61 LLGKIYLALGDYAAAEKELRKALSLgYPKNqVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAA-ELLALRGLAYLGLG 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  212 QYSAAifdlkkadEAPFQLAQVPLSDSvwvrikrqIPTMITQAYYQMGPDKYADLIAYAEPIILNDKRAVeksDIARLLG 291
Cdd:TIGR02917  140 QLELA--------QKSYEQALAIDPRS--------LYAKLGLAQLALAENRFDEARALIDEVLTADPGNV---DALLLKG 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  292 DIYFNQGKFSKSAEIYAQYLLINESKRAVFqsntegipLKQAFSLFKSGQYQESEILLsklinkETLSDSLSQ--LVHYQ 369
Cdd:TIGR02917  201 DLLLSLGNIELALAAYRKAIALRPNNIAVL--------LALATILIEAGEFEEAEKHA------DALLKKAPNspLAHYL 266

                          250       260
                   ....*....|....*....|....*
gi 1390256476  370 IGMSQFHLKNYDAAGTSLEKAILIN 394
Cdd:TIGR02917  267 KALVDFQKKNYEDARETLQDALKSA 291
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 162-314 1.49e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  162 EIRFQLAICYLQVGLNTKALSLF-ELLSNDDNESVAYAasyYSGLLKLNLKQYSAAIFDLKKAdeapfqLAQVPLSDSVW 240
Cdd:COG4783      5 EALYALAQALLLAGDYDEAEALLeKALELDPDNPEAFA---LLGEILLQLGDLDEAIVLLHEA------LELDPDEPEAR 75

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1390256476  241 VrikrqiptMITQAYYQMGpdKYADLIAYAEPIIlndKRAVEKSDIARLLGDIYFNQGKFSKSAEIYAQYLLIN 314
Cdd:COG4783     76 L--------NLGLALLKAG--DYDEALALLEKAL---KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 288-391 1.87e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.60  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  288 RLLGDIYFNQGKFSKSAEIYAQYLLINESKRAVFqsntegipLKQAFSLFKSGQYQESEILLSKLINKetlsDSLSQLVH 367
Cdd:COG4235     21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADAL--------LDLAEALLAAGDTEEAEELLERALAL----DPDNPEAL 88

                           90       100
                   ....*....|....*....|....
gi 1390256476  368 YQIGMSQFHLKNYDAAGTSLEKAI 391
Cdd:COG4235     89 YLLGLAAFQQGDYAEAIAAWQKLL 112
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
290-418 2.31e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 2.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  290 LGDIYFNQGKFSKSAEIYAQYLLINeSKRAVFQSNtegiplkQAFSLFKSGQYQESEILLSKLINKetlsDSLSQLVHYQ 369
Cdd:COG0457     48 LGLAYLRLGRYEEALADYEQALELD-PDDAEALNN-------LGLALQALGRYEEALEDYDKALEL----DPDDAEALYN 115

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1390256476  370 IGMSQFHLKNYDAAGTSLEKAILINWDkslSEDAYFNQLVALENRGSFD 418
Cdd:COG0457    116 LGLALLELGRYDEAIEAYERALELDPD---DADALYNLGIALEKLGRYE 161
TPR_19 pfam14559
Tetratricopeptide repeat;
142-199 6.78e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.02  E-value: 6.78e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  142 AGEYQDAIQYIEQRVSIL--DPEIRFQLAICYLQVGLNTKALSLFELLSNDDNESVAYAA 199
Cdd:pfam14559    1 EGDYAEALELLEQALAEDpdNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 134-271 7.25e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.25  E-value: 7.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390256476  134 EIGSFLYKAGEYQDAIQYIEQRVSIL--DPEIRFQLAICYLQVGLNTKALSLF-ELLSNDDNESVAYaasYYSGLLKLNL 210
Cdd:COG4783      9 ALAQALLLAGDYDEAEALLEKALELDpdNPEAFALLGEILLQLGDLDEAIVLLhEALELDPDEPEAR---LNLGLALLKA 85

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390256476  211 KQYSAAIFDLKKAdeapfqLAQVPLSDSVWVRIKRqiptmitqAYYQMGpdKYADLIAYAE 271
Cdd:COG4783     86 GDYDEALALLEKA------LKLDPEHPEAYLRLAR--------AYRALG--RPDEAIAALE 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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