|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
4.63e-92 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 295.16 E-value: 4.63e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVRQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 90 YQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
2.84e-64 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 215.56 E-value: 2.84e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVRQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
1.03e-61 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 207.83 E-value: 1.03e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVRQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
2.38e-37 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 138.81 E-value: 2.38e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 76 IHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 1378869096 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
596-1372 |
3.55e-28 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 124.40 E-value: 3.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 596 IKETSSKLSKIEFEKRQIRKELEHYKEKGERAE---ELENELHHLEKENELLQKKitnlkitcEKIEALEQENSELEREN 672
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQAEKAErykELKAELRELELALLVLRLE--------ELREELEELQEELKEAE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 673 RKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA-SMKMAQLQLENKELESEKEQLKKGLELMKASFKKT 751
Cdd:TIGR02168 253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEiSRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 752 ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 832 KQLEKENKRLRQQAEIKDTTLEENNVK--IGNLEKENKTLFKEIgiykESCIRLKELEKENKELVKRATIDIKTLVTLRE 909
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQ----EELERLEEALEELREELEEAEQALDAAERELA 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 910 DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL------LHDEQSTDDRYKL-----LESKLESTLKKSLEIKEEKIAAL 978
Cdd:TIGR02168 486 QLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvLSELISVDEGYEAaieaaLGGRLQAVVVENLNAAKKAIAFL 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 979 E-------ARLEESTNYNQQLRQELKTVKKNYE-----------------------------------ALKQRQ------ 1010
Cdd:TIGR02168 566 KqnelgrvTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalsyllggvlvvddldnALELAKklrpgy 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1011 ----DEEKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQ 1086
Cdd:TIGR02168 646 rivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1087 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLH 1166
Cdd:TIGR02168 726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1167 ERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRynqllkqkgqLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLcgeN 1246
Cdd:TIGR02168 806 DELRAELTLLNEEAANLRERLESLERRIAATERR----------LEDLEEQIEELSEDIESLAAEIEELEELIEEL---E 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1247 DRLNHtynqLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDitstklnnqcELLSQLKGNLEEENRHL 1326
Cdd:TIGR02168 873 SELEA----LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR----------EKLAQLELRLEGLEVRI 938
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 1378869096 1327 LDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKL 1372
Cdd:TIGR02168 939 DNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1223 |
8.75e-25 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 112.85 E-value: 8.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 610 KRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 690 ESLEKENSQLDEENLELRRNVESLKcasmkmaqlqLENKELESEKEQLKKglelmkasfkkterlevsYQGLDTENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK----------KEIEELEEKVKELKE------------------LKEKAEEYIKLS 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 770 KALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE----KENKRLRQQA 845
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeakaKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 846 EIKDTTLEENNVKIGNLEKENKTLFKEIgiyKESCIRLKELEKENKELvKRATIDIKTlVTLREDLVSEKLKTQQMNNDL 925
Cdd:PRK03918 380 RLTGLTPEKLEKELEELEKAKEEIEEEI---SKITARIGELKKEIKEL-KKAIEELKK-AKGKCPVCGRELTEEHRKELL 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 926 EKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKL--ESTLKKSLEIKEEkIAALEARLEEstnYNqqlRQELKTVKKNY 1003
Cdd:PRK03918 455 EEYTAELKRIEKELKEIEEKERKLRKELRELEKVLkkESELIKLKELAEQ-LKELEEKLKK---YN---LEELEKKAEEY 527
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1004 EALKQRQDEekmvqssppVSGEDNKWEREsqetTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN-NNLQAQI 1082
Cdd:PRK03918 528 EKLKEKLIK---------LKGEIKSLKKE----LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERL 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1083 LALQ---RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESVIKEREDLKSLYDSliKDH 1159
Cdd:PRK03918 595 KELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKYSE--EEY 661
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 1160 EKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQE 1223
Cdd:PRK03918 662 EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
470-1007 |
1.79e-24 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 112.08 E-value: 1.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 470 QSLTKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENeiiqekqslqncqnlskdLMKEKAQLEKTIETLRE-- 547
Cdd:PRK03918 200 KELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEE------------------LEKELESLEGSKRKLEEki 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 548 -NSERQIKILEQENEHLNQTVSSLRQrsqisaearVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGER 626
Cdd:PRK03918 262 rELEERIEELKKEIEELEEKVKELKE---------LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 627 AEELENELHHLEKENELLQKKITNLKITCEKIEALEQ------------ENSELERENRKYKKTLDSFKNLTFQLESLEK 694
Cdd:PRK03918 333 LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAkkeelerlkkrlTGLTPEKLEKELEELEKAKEEIEEEISKITA 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKElESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALEN 774
Cdd:PRK03918 413 RIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqaeikdtTLEE 854
Cdd:PRK03918 492 ESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA--------ELEK 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 855 nnvKIGNLEKENKTLFKEIGIYKESCI-----RLKELEK------ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNN 923
Cdd:PRK03918 564 ---KLDELEEELAELLKELEELGFESVeeleeRLKELEPfyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEK 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 924 DLEKLTHELEKIGLNkerllhdeqSTDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNY 1003
Cdd:PRK03918 641 RLEELRKELEELEKK---------YSEEEYEELREEYLE-LSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAK 710
|
....
gi 1378869096 1004 EALK 1007
Cdd:PRK03918 711 KELE 714
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
506-1204 |
2.17e-24 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 111.27 E-value: 2.17e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 506 KVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIEtlreNSERQIKILEQENEHLNQTVSSLRQrsqisaeaRVKDI 585
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKIN----NSNNKIKILEQQIKDLNDKLKKNKD--------KINKL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 586 EKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQEN 665
Cdd:TIGR04523 102 NSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKN---IDKFLTEIKKKEKELEKLNNKYNDLK---KQKEELENEL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 666 SELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCasmkmaqlqlENKELESEKEQLKKGLELMK 745
Cdd:TIGR04523 176 NLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKK----------QNNQLKDNIEKKQQEINEKT 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 746 ASFKKTER----LEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEME--------NQTLQKNL-EELKISSKRLEQ 812
Cdd:TIGR04523 246 TEISNTQTqlnqLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEisdlnnqkEQDWNKELkSELKNQEKKLEE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKE 892
Cdd:TIGR04523 326 IQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 893 LVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD-EQSTDDRYKLLE--SKLESTLKKSLE 969
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNlDNTRESLETQLKvlSRSINKIKQNLE 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE---EKMVQSSPPVSGEDNKWERESQETTRELLKVKD- 1045
Cdd:TIGR04523 486 QKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKlesEKKEKESKISDLEDELNKDDFELKKENLEKEIDe 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1046 ---RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN 1122
Cdd:TIGR04523 566 knkEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1123 QNAQLLIQQSSLENENESVIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLED 1199
Cdd:TIGR04523 646 EVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIelmKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDE 725
|
....*
gi 1378869096 1200 RYNQL 1204
Cdd:TIGR04523 726 FSKEL 730
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
529-1299 |
8.92e-24 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 110.15 E-value: 8.92e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 529 KDLMKEKAQLEKTI-----ETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI--LHESIKETSS 601
Cdd:TIGR02168 216 KELKAELRELELALlvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIeeLQKELYALAN 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 602 KLSKIEFEKRQIRKELEH----YKEKGERAEELENELHHLEKENELLQKKITNLKITCE----KIEALEQENSELERENR 673
Cdd:TIGR02168 296 EISRLEQQKQILRERLANlerqLEELEAQLEELESKLDELAEELAELEEKLEELKEELEsleaELEELEAELEELESRLE 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 674 KYKKTLDSFKNLTFQLESlekensQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTER 753
Cdd:TIGR02168 376 ELEEQLETLRSKVAQLEL------QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 754 LEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQL------ 827
Cdd:TIGR02168 450 EE-----LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgv 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 828 --------EKDKKQLEKENKRLRQQAEIKDttLEENNVKIGNLEKEN--KTLFKEIGIYKESCIRLKELE-KENKELVKR 896
Cdd:TIGR02168 525 lselisvdEGYEAAIEAALGGRLQAVVVEN--LNAAKKAIAFLKQNElgRVTFLPLDSIKGTEIQGNDREiLKNIEGFLG 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 897 ATIDIKTLVTLREDLVSEKLKT-------QQMNNDLEKLTHELEKIGLNKERLLHD----EQSTDDRYKLLESKLE-STL 964
Cdd:TIGR02168 603 VAKDLVKFDPKLRKALSYLLGGvlvvddlDNALELAKKLRPGYRIVTLDGDLVRPGgvitGGSAKTNSSILERRREiEEL 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 965 KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMV------------QSSPPVSGEDNKWERE 1032
Cdd:TIGR02168 683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDlarleaeveqleERIAQLSKELTELEAE 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST 1112
Cdd:TIGR02168 763 IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1113 LNSQSTSLmnqNAQLLIQQSSLENENESVIKEREDLKSLYDslikdheklellherqasEYESLIAKHGTLKSAHKNLEV 1192
Cdd:TIGR02168 843 LEEQIEEL---SEDIESLAAEIEELEELIEELESELEALLN------------------ERASLEEALALLRSELEELSE 901
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1193 EHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLK-NKNHETVAAEYKKLCGENDRLnhtYNQLLKETEVLQTDHKNLK 1271
Cdd:TIGR02168 902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRiDNLQERLSEEYSLTLEEAEAL---ENKIEDDEEEARRRLKRLE 978
|
810 820 830
....*....|....*....|....*....|
gi 1378869096 1272 SLLNssRLEQTRLEA--EFSKLKEQYQQLD 1299
Cdd:TIGR02168 979 NKIK--ELGPVNLAAieEYEELKERYDFLT 1006
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
1.86e-23 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 108.61 E-value: 1.86e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 181 MSQEEIEPLLKNMVLHLKRLIDERDEHSETIIELSEERDGLHfpphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEmerdmdrKKIEELMEENMTLEMAqK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE-------KRLEELEERHELYEEA-K 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 421 QSMDESLHL-----GWELEQISRTSELSEAPQKSLGHEVNELTsSRLLKLEMENQSLTKTVEELRSTMDSAEGTTSKILK 495
Cdd:PRK03918 369 AKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 496 IEKENQRLSKKVEIleneiiqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQR 573
Cdd:PRK03918 448 EHRKELLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKEL 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 574 SQISAEARVKDIEKENKiLHESIKEtssKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK03918 509 EEKLKKYNLEELEKKAE-EYEKLKE---KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 654 TCekIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEenlelrrnveslkcASMKMAQLQLENKELESE 733
Cdd:PRK03918 585 ES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDK--------------AFEELAETEKRLEELRKE 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 734 KEQLKKglelmKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Cdd:PRK03918 649 LEELEK-----KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERV 723
|
.
gi 1378869096 814 E 814
Cdd:PRK03918 724 E 724
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
249-1079 |
1.96e-23 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 108.99 E-value: 1.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnLLSDARSARMYRDELDALREKavrVDKLESE 328
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLE---VSELEEEIEELQKELYALANE---ISRLEQQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 329 VSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDM 400
Cdd:TIGR02168 304 KQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEEQLET 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 401 DRKKIEELmEENMTLEMAQKQSMDEslhlgwELEQISRTSELSEAPQKSLGhevNELTSSRLLKLEMENQSLTKTVEELR 480
Cdd:TIGR02168 384 LRSKVAQL-ELQIASLNNEIERLEA------RLERLEDRRERLQQEIEELL---KKLEEAELKELQAELEELEEELEELQ 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 481 STMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEN 560
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 561 EHLNQTVSSLRQRSQ----ISAEARVKDIE--KENKILHESIKE-TSSKLSKIEFEKRQIRKELEHYKEKGERAEELENE 633
Cdd:TIGR02168 534 GYEAAIEAALGGRLQavvvENLNAAKKAIAflKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 634 LHhlekenELLQKKITNLKITCEKIEALEQENsELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVEsl 713
Cdd:TIGR02168 614 LR------KALSYLLGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEE-- 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 714 kcasmKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEvsyQGLDTENQRLQKALENSNKKIQQLESELQDLEMEN 793
Cdd:TIGR02168 685 -----KIEELEEKIAELEKALAELRKELEELEEELEQLRKEL---EELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 794 QTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:TIGR02168 757 TELEAEIEELE---ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 874 GIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEklktqqmnndLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----------LEALLNERASLEEALALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 954 KLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELktvkknyeALKQRQDEEKMVQSSPPVSGEDNKWERES 1033
Cdd:TIGR02168 904 RELESKR-SELRRELEELREKLAQLELRLEGLEVRIDNLQERL--------SEEYSLTLEEAEALENKIEDDEEEARRRL 974
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 1378869096 1034 QETTRELlkvkDRLIEVernNATLQAEKQALKTQLKQLETQNNNLQ 1079
Cdd:TIGR02168 975 KRLENKI----KELGPV---NLAAIEEYEELKERYDFLTAQKEDLT 1013
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1070 |
2.58e-23 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 108.67 E-value: 2.58e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQsmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIR--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 425 eslhlgweleqiSRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKtVEELRSTMDSAEGTTSKILKIEKENQRLS 504
Cdd:pfam15921 134 ------------RRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 505 KKvEILENEIIQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIK-ILEQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIElLLQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETSS----KLSKIEFEKRQIRKELEHYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 635 HHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKYKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRNVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLLAdLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 714 KC--------ASMKMAQLQLENK----------ELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 776 NKKIQQLES-------ELQDLEMEN---QTLQKNLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLfkeIGIYKESCIRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 908 REDLvsEKLKtQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES------KLESTLKKSLEIKEEKIAALEAR 981
Cdd:pfam15921 673 SEDY--EVLK-RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamKVAMGMQKQITAKRGQIDALQSK 749
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 982 LeestnynQQLRQELKTVKKNYEALKqrQDEEKMVQSSPPVSGEDNKW--ERESQETTRELLKVKDRLIEVERNNATLQ- 1058
Cdd:pfam15921 750 I-------QFLEEAMTNANKEKHFLK--EEKNKLSQELSTVATEKNKMagELEVLRSQERRLKEKVANMEVALDKASLQf 820
|
810
....*....|..
gi 1378869096 1059 AEKQALKTQLKQ 1070
Cdd:pfam15921 821 AECQDIIQRQEQ 832
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
543-1072 |
4.43e-23 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 107.46 E-value: 4.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 543 ETLRENSERQIKILEQENEHLnqtvsslrqRSQISAEARVKDIEKENK-----ILHEsIKETSSKLSKIEFEKRQIRKEL 617
Cdd:PRK03918 161 ENAYKNLGEVIKEIKRRIERL---------EKFIKRTENIEELIKEKEkeleeVLRE-INEISSELPELREELEKLEKEV 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 618 EHYKEKGERAEELENELHHLEKENELLQKKITNL----KITCEKIEALEQ---ENSELERENRKYKKTLDSFKNLTFQLE 690
Cdd:PRK03918 231 KELEELKEEIEELEKELESLEGSKRKLEEKIRELeeriEELKKEIEELEEkvkELKELKEKAEEYIKLSEFYEEYLDELR 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 691 SLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLEL---MKASFKKTERLEVSYQGLDTEN-- 765
Cdd:PRK03918 311 EIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeAKAKKEELERLKKRLTGLTPEKle 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 766 ---QRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELK-------ISSKRLEQLEKEN--KSLEQETSQLEKDKKQ 833
Cdd:PRK03918 391 kelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpVCGRELTEEHRKEllEEYTAELKRIEKELKE 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 834 LEKENKRLRQQAEIKDTTLEENNVKIgnlekENKTLFKEIGIYKE--SCIRLKELEKENKEL--VKRATIDIKTLVtlrE 909
Cdd:PRK03918 471 IEEKERKLRKELRELEKVLKKESELI-----KLKELAEQLKELEEklKKYNLEELEKKAEEYekLKEKLIKLKGEI---K 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 910 DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH--------DEQSTDDRYKLLESKLESTL-----KKSLEIKEEKIA 976
Cdd:PRK03918 543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKeleelgfeSVEELEERLKELEPFYNEYLelkdaEKELEREEKELK 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 977 ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQssppVSGEDNKWERESQETTRELLKVKDRLIEVERNNAT 1056
Cdd:PRK03918 623 KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE----LREEYLELSRELAGLRAELEELEKRREEIKKTLEK 698
|
570
....*....|....*.
gi 1378869096 1057 LQAEKQALKTQLKQLE 1072
Cdd:PRK03918 699 LKEELEEREKAKKELE 714
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
465-935 |
2.23e-21 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 101.64 E-value: 2.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 465 LEMENQSLTKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIE 543
Cdd:TIGR04523 234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYK-- 621
Cdd:TIGR04523 314 SELKNQEKKLEEIQNQISQNNKIISQLNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLEsq 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 622 ---------EKGERAEELENELHHLEKENELLQKKITNLKITCEK-------------------------IEALEQENSE 667
Cdd:TIGR04523 393 indleskiqNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKnnseikdltnqdsvkeliiknldntRESLETQLKV 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 668 LERENRKYKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLEL 743
Cdd:TIGR04523 473 LSRSINKIKQNLEqkqkELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 744 MKASFKKtERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISskrLEQLEKENKSLEQE 823
Cdd:TIGR04523 550 DDFELKK-ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK---ISSLEKELEKAKKE 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIG-IYKESCIRLKELEKENKELVKRAT--ID 900
Cdd:TIGR04523 626 NEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDdIIELMKDWLKELSLHYKKYITRMIriKD 705
|
490 500 510
....*....|....*....|....*....|....*
gi 1378869096 901 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:TIGR04523 706 LPKLEEKYKEIEKELKKLDEFSKELENIIKNFNKK 740
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
2.83e-21 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 91.95 E-value: 2.83e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDAS--LRIHNLSILVRQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 94 LQQLIM-MSLPNVLIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
504-1208 |
4.20e-21 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 101.30 E-value: 4.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 504 SKKVEILENEIIQEKQSLQNCQNLS---KDLMKEKAQLE--------KTIETLRENSERQIKILEQENEHLNQTVSSLRQ 572
Cdd:TIGR02169 186 IERLDLIIDEKRQQLERLRREREKAeryQALLKEKREYEgyellkekEALERQKEAIERQLASLEEELEKLTEEISELEK 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 573 RSQiSAEARVKDIEKE-NKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEE----LENELHHLEKENELLQKK 647
Cdd:TIGR02169 266 RLE-EIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEErlakLEAEIDKLLAEIEELERE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 648 ITNLKITCEKIEA--------LEQENSELERENRKYKKTLDSFKNLTfqlESLEKENSQLDEENLELRRNVESLKCASMK 719
Cdd:TIGR02169 345 IEEERKRRDKLTEeyaelkeeLEDLRAELEEVDKEFAETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSEE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 720 MAQLQLENKELESEKEQLKKGLELMKASFKKTERlevsyqgldtENQRLQKALENSNKKIQQLESELQDLEMENQTLQKN 799
Cdd:TIGR02169 422 LADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 800 LEELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQL-----------------------EKENKRLRQQA 845
Cdd:TIGR02169 492 LAEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERYataievaagnrlnnvvveddavaKEAIELLKRRK 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 846 EIKDTTLEENNVKIGNLEKENKTLFKEIGIykesCIRLKELEKENKELVK---------------RATIDIKTLVTLRED 910
Cdd:TIGR02169 572 AGRATFLPLNKMRDERRDLSILSEDGVIGF----AVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMVTLEGE 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 911 LV---------------------SEKLKTQQMNNDLEKL----------------------------THELEKIGLNKER 941
Cdd:TIGR02169 648 LFeksgamtggsraprggilfsrSEPAELQRLRERLEGLkrelsslqselrrienrldelsqelsdaSRKIGEIEKEIEQ 727
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 942 LLHDEQSTDDRYKLLESKLEST-------------LKKSLEIKEEKIAALEARLEEStnYNQQLRQELKTVKKNYEALK- 1007
Cdd:TIGR02169 728 LEQEEEKLKERLEELEEDLSSLeqeienvkselkeLEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEe 805
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1008 QRQDEEKMVQSsppVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR 1087
Cdd:TIGR02169 806 EVSRIEARLRE---IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1088 QTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKER-------------EDLKSLYDS 1154
Cdd:TIGR02169 883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKgedeeipeeelslEDVQAELQR 962
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 1155 LIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQK 1208
Cdd:TIGR02169 963 VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1281 |
5.24e-21 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 101.20 E-value: 5.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 497 EKENQRLSKKVEILEN---------EIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQikiLEQENEHLNQTV 567
Cdd:pfam02463 169 RKKKEALKKLIEETENlaeliidleELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLK---LNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 568 SSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELH----HLEKENEL 643
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEeklkESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 644 LQKKITNLKitcEKIEALEQENSELERENRKYKKTLDSFKNLtfQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Cdd:pfam02463 326 AEKELKKEK---EEIEELEKELKELEIKREAEEEEEEELEKL--QEKLEQLEEELLAKKKLESERLSSAAKLKEEELELK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 724 QLENKELESEKEqLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTlqKNLEEL 803
Cdd:pfam02463 401 SEEEKEAQLLLE-LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE--DLLKET 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKES--CI 881
Cdd:pfam02463 478 QLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTA 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE 961
Cdd:pfam02463 558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 962 STLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN-YEALKQRQDEEKMVQSSPPVSGE--DNKWERESQETTR 1038
Cdd:pfam02463 638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIqELQEKAESELAKEEILRRQLEIKkkEQREKEELKKLKL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1039 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQST 1118
Cdd:pfam02463 718 EAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1119 SLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELlhERQASEYESLIAKHGTLKSAHKNLEVEHKDLE 1198
Cdd:pfam02463 798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLK 875
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1199 DRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSR 1278
Cdd:pfam02463 876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955
|
...
gi 1378869096 1279 LEQ 1281
Cdd:pfam02463 956 EEE 958
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
628-1350 |
2.26e-20 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 98.55 E-value: 2.26e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 628 EELENELHHLEKENELLQKKITNL-KITCEKIEALEQENSELErENRKYKKTLDSfknltfqleSLEKENSQLDEENLEL 706
Cdd:TIGR04523 36 KQLEKKLKTIKNELKNKEKELKNLdKNLNKDEEKINNSNNKIK-ILEQQIKDLND---------KLKKNKDKINKLNSDL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 707 RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSyqgLDTENQRLQKALENSNKKIQQLESEL 786
Cdd:TIGR04523 106 SKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Cdd:TIGR04523 183 LNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQ 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 867 KTLfkeigiykescirLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKERllhde 946
Cdd:TIGR04523 263 NKI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK----- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 947 qstddrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKnyealkqrqdeekmvqssppvsgED 1026
Cdd:TIGR04523 305 ----------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK-----------------------EL 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1027 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1106
Cdd:TIGR04523 352 TNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERL 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1107 QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSA 1186
Cdd:TIGR04523 432 KETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1187 HKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKM--LLKNKNHETVAAEYKKlcgENDRLNHTYNQLLKETEVLQ 1264
Cdd:TIGR04523 512 VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDdfELKKENLEKEIDEKNK---EIEELKQTQKSLKKKQEEKQ 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1265 TDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1344
Cdd:TIGR04523 589 ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKI 668
|
....*.
gi 1378869096 1345 MESKDL 1350
Cdd:TIGR04523 669 KESKTK 674
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-904 |
2.94e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 98.60 E-value: 2.94e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESEVSR 331
Cdd:TIGR02169 288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 362 LKEELEDLR---AELEEVDKEFAETRDELKDYREKLEKLK---REINELKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKT--------------VE 477
Cdd:TIGR02169 436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV-EKELSKLQRELAEAEAQaraseervrggravEE 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 478 ELRSTMDSAEGTTSKILKIEKENQrlsKKVEI-----LENEIIQEKQSLQNCQNLSKDL---------MKEKAQLEKTIE 543
Cdd:TIGR02169 515 VLKASIQGVHGTVAQLGSVGERYA---TAIEVaagnrLNNVVVEDDAVAKEAIELLKRRkagratflpLNKMRDERRDLS 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 544 TLRENSERQIKI-------------------------LEQENEHLNQ-----------------TVSSLRQRSQISAEAR 581
Cdd:TIGR02169 592 ILSEDGVIGFAVdlvefdpkyepafkyvfgdtlvvedIEAARRLMGKyrmvtlegelfeksgamTGGSRAPRGGILFSRS 671
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 582 VKDIEKEnkiLHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKitcEK 657
Cdd:TIGR02169 672 EPAELQR---LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkigEIEKEIEQLEQEEEKLKERLEELE---ED 745
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 658 IEALEQENSELEREnrkykktldsfknltfqLESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLENKELESEKEQL 737
Cdd:TIGR02169 746 LSSLEQEIENVKSE-----------------LKELEARIEELEEDLHKLEEALNDLE-ARLSHSRIPEIQAELSKLEEEV 807
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 738 KKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKEN 817
Cdd:TIGR02169 808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE---AALRDLESRL 884
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELvKRA 897
Cdd:TIGR02169 885 GDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL-QRV 963
|
....*..
gi 1378869096 898 TIDIKTL 904
Cdd:TIGR02169 964 EEEIRAL 970
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1074 |
3.37e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 98.60 E-value: 3.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQME---IELKRLQQ-ENMNLLSDARSARMYRDELDALREKAVRV-DKLE 326
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAEryqALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEElEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 327 SEVS----RYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISelekRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTS-----ELSEAPQK--SLGHEVNELTSSRLLKLEmEN 469
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdELKDYREKleKLKREINELKRELDRLQE-EL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 470 QSLTKTVEELRSTMDSAEG--------TTSKILKIEKENQRLSKKVEIL---ENEIIQEKQSLQNCQNLSKDLMKEKAQL 538
Cdd:TIGR02169 416 QRLSEELADLNAAIAGIEAkineleeeKEDKALEIKKQEWKLEQLAADLskyEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 539 EKTIETLRENSE---RQIKILEQENEHLNQTVSSL---RQRSQISAE----ARVKDIEKENKILHESIKE--TSSKLSKI 606
Cdd:TIGR02169 496 EAQARASEERVRggrAVEEVLKASIQGVHGTVAQLgsvGERYATAIEvaagNRLNNVVVEDDAVAKEAIEllKRRKAGRA 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 607 EF----EKRQIRKELEHYKEKGerAEELENELHHLEKENELLQKKITNLKITCEKIEALeqenselerenrkyKKTLDSF 682
Cdd:TIGR02169 576 TFlplnKMRDERRDLSILSEDG--VIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAA--------------RRLMGKY 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 683 KNLTFQLESLEKENS----------------QLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKkglELMKA 746
Cdd:TIGR02169 640 RMVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS---QELSD 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 747 SFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLE--ELKISSKRLEQLEKENKSLEQET 824
Cdd:TIGR02169 714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEARLSHSRI 793
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 825 SQLEKDKKQLEKENKRLRQQaeikdttLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKElvkratiDIKTL 904
Cdd:TIGR02169 794 PEIQAELSKLEEEVSRIEAR-------LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK-------EIENL 859
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 905 VTLREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddrYKLLESKLEsTLKKSLEIKEEKIAALEARLEe 984
Cdd:TIGR02169 860 NGKKEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ-----LRELERKIE-ELEAQIEKKRKRLSELKAKLE- 927
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 985 stNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQAL 1064
Cdd:TIGR02169 928 --ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
|
890
....*....|
gi 1378869096 1065 KTQLKQLETQ 1074
Cdd:TIGR02169 1006 LERIEEYEKK 1015
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-1374 |
1.23e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 96.68 E-value: 1.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 594 ESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitcEKIEALEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 674 KykktldsfknLTFQLESLEKENSQLDEENLELRRNVESLkcASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTER 753
Cdd:TIGR02169 255 K----------LTEEISELEKRLEEIEQLLEELNKKIKDL--GEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 754 ----LEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELkisSKRLEQLEKENKSLEQETSQLEK 829
Cdd:TIGR02169 323 rlakLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEV---DKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKenktlfkeigiykesciRLKELEKENKELVKRATIDIKTLVTLRE 909
Cdd:TIGR02169 400 EINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------------KINELEEEKEDKALEIKKQEWKLEQLAA 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 910 DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY-------KLLESKLES---TLKKSLEIKEEKIAALE 979
Cdd:TIGR02169 463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraveEVLKASIQGvhgTVAQLGSVGERYATAIE 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 980 ARLeeSTNYNQQLRQELKTVKKNYEALKQRQDEE-------KMVQSSPPVSGE---------------DNKWER------ 1031
Cdd:TIGR02169 543 VAA--GNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplnKMRDERRDLSILsedgvigfavdlvefDPKYEPafkyvf 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1032 ------ESQETTRELLkVKDRLIEVE---------------------RNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1084
Cdd:TIGR02169 621 gdtlvvEDIEAARRLM-GKYRMVTLEgelfeksgamtggsraprggiLFSRSEPAELQRLRERLEGLKRELSSLQSELRR 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1085 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Cdd:TIGR02169 700 IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1165 -LHERQASEYESLI----AKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEkmLLKNKNHEtvaaey 1239
Cdd:TIGR02169 780 aLNDLEARLSHSRIpeiqAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI--DLKEQIKS------ 851
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1240 kkLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL 1319
Cdd:TIGR02169 852 --IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEAL 929
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1378869096 1320 EEENRHLLD--------------------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1374
Cdd:TIGR02169 930 EEELSEIEDpkgedeeipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
730-1320 |
3.88e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 94.75 E-value: 3.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 730 LESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR 809
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqAEIKDttLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKE 889
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELK--KEIEE--LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 890 NKELVKRatidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGlNKERLLHDEQSTDDRYKLLESKLEStlkKSLE 969
Cdd:PRK03918 316 LSRLEEE----INGIEERIKELEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTG---LTPE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSPPVSG---EDNKWERESQETTRELLKVKDR 1046
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1047 LIEVErnnatlqAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1126
Cdd:PRK03918 468 LKEIE-------EKERKLRKELRELEK--------VLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKE 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1127 LLIQqssLENENESVIKEREDLKSLYDSLIKDHEKLELLhERQASEYESLIAKHGTlkSAHKNLEVEHKDLE---DRYNQ 1203
Cdd:PRK03918 533 KLIK---LKGEIKSLKKELEKLEELKKKLAELEKKLDEL-EEELAELLKELEELGF--ESVEELEERLKELEpfyNEYLE 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1204 LLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNqllketevlQTDHKNLKSLLNSSRLEQTR 1283
Cdd:PRK03918 607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS---------EEEYEELREEYLELSRELAG 677
|
570 580 590
....*....|....*....|....*....|....*..
gi 1378869096 1284 LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1320
Cdd:PRK03918 678 LRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
136-873 |
6.76e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 94.35 E-value: 6.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 136 QKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQwmevtdMSQEEIEPLLKNMVLHLKRLIDERDEHSETIIELS 215
Cdd:TIGR02168 277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLE------RQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 216 EERDGLhfpphassSAQSPcgspgmKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEN 295
Cdd:TIGR02168 351 EELESL--------EAELE------ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 296 MNLLSDARSARMYRDELDalrekavrVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGtrarsd 375
Cdd:TIGR02168 417 ERLQQEIEELLKKLEEAE--------LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER------ 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 376 klhelekENLQLKAKLHDMemerdmdrkkiEELMEENMTLEMAQKQSMDE----SLHLGWELEQISRTSELSEAPQKSLG 451
Cdd:TIGR02168 483 -------ELAQLQARLDSL-----------ERLQENLEGFSEGVKALLKNqsglSGILGVLSELISVDEGYEAAIEAALG 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 452 hevneltsSRLLKLEMEN-QSLTKTVEELRSTmdSAEGTTSKILKIEKENQRLSKKVEILENEiiqekqslQNCQNLSKD 530
Cdd:TIGR02168 545 --------GRLQAVVVENlNAAKKAIAFLKQN--ELGRVTFLPLDSIKGTEIQGNDREILKNI--------EGFLGVAKD 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 531 LMKEKAQLEKTIETL---------RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHES--IKET 599
Cdd:TIGR02168 607 LVKFDPKLRKALSYLlggvlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSA----KTNSSILERRreIEEL 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 600 SSKLSKIEFEKRQIRKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTL 679
Cdd:TIGR02168 683 EEKIEELEEKIAELEKALAELRKE---LEELEEELEQLRKELEELSRQISALR---KDLARLEAEVEQLEERIAQLSKEL 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 680 dsfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELMKASF-KKTERLEVSY 758
Cdd:TIGR02168 757 ---TELEAEIEELEERLEEAEEELAEAEAEIEELE---AQIEQLKEELKALREALDELRAELTLLNEEAaNLRERLESLE 830
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 759 QGLD---TENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:TIGR02168 831 RRIAateRRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEELRELE 907
|
730 740 750
....*....|....*....|....*....|....*...
gi 1378869096 836 KENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:TIGR02168 908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
183-833 |
2.45e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 92.44 E-value: 2.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 183 QEEIEPLLKNMVLHLKRLIDERDEHSETIIELSEERDGLHFPPHASSSAQSPCGspgmKRTESRQHLSVELADAKAKIRR 262
Cdd:TIGR02169 356 TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD----RLQEELQRLSEELADLNAAIAG 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 263 LRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnlLSDarsarmYRDELDALREKavrVDKLESEVSRYKERLHDIEfy 342
Cdd:TIGR02169 432 IEAKINELEEEKEDKALEIKKQEWKLEQLAAD----LSK------YEQELYDLKEE---YDRVEKELSKLQRELAEAE-- 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 343 kARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE-----NLQLKAKLHDMEMERDMDRKK-IEELMEEN---M 413
Cdd:TIGR02169 497 -AQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataiEVAAGNRLNNVVVEDDAVAKEaIELLKRRKagrA 575
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 414 TL----EMAQKQSMDESLH----LGWELEQISRTSELSEAPQKSLGHE--VNELTSS-------RLLKLE---------M 467
Cdd:TIGR02169 576 TFlplnKMRDERRDLSILSedgvIGFAVDLVEFDPKYEPAFKYVFGDTlvVEDIEAArrlmgkyRMVTLEgelfeksgaM 655
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 468 ENQSLTKTVEELRSTMDSAE--GTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETL 545
Cdd:TIGR02169 656 TGGSRAPRGGILFSRSEPAElqRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL 735
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 546 RE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKETSSKLSKIEFEKRQIRKele 618
Cdd:TIGR02169 736 KErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEIQAELSKLEEEVSRIEA--- 812
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 619 hykekgeRAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTLDSFKNltfQLESLEKENSQ 698
Cdd:TIGR02169 813 -------RLREIEQKLNRLTLEKEYLEKEIQELQ---EQRIDLKEQIKSIEKEIENLNGKKEELEE---ELEELEAALRD 879
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 699 LDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKA---LENS 775
Cdd:TIGR02169 880 LESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDV 956
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1378869096 776 NKKIQQLESELQDLEMEN-------QTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:TIGR02169 957 QAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELK---EKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
533-1219 |
2.80e-18 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.92 E-value: 2.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 533 KEKAqlEKTIETLRENSERqIKILEQENEhlnqtvsslRQRSQISAEARVKdieKENKILHESIKETSSKLSKIEFEKRQ 612
Cdd:COG1196 174 KEEA--ERKLEATEENLER-LEDILGELE---------RQLEPLERQAEKA---ERYRELKEELKELEAELLLLKLRELE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 613 IRKElehykEKGERAEELENELHHLEKENELLQKKITNLKitcekiEALEQENSELERENRKYKKTLDSFKNLTFQLESL 692
Cdd:COG1196 239 AELE-----ELEAELEELEAELEELEAELAELEAELEELR------LELEELELELEEAQAEEYELLAELARLEQDIARL 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 693 EKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLkkglelmkasfkktERLEVSYQGLDTENQRLQKAL 772
Cdd:COG1196 308 EERRRELEERLEELEEELAELE------EELEELEEELEELEEEL--------------EEAEEELEEAEAELAEAEEAL 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 773 ENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEALRAAAELA---AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 853 EENNVKIGNLEKENKTLFKEIgiykescIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHEL 932
Cdd:COG1196 445 EEAAEEEAELEEEEEALLELL-------AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 933 EKIGLnkERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKknyeALKQRQDE 1012
Cdd:COG1196 518 GLRGL--AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR----ARAALAAA 591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1013 EKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVERN---NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Cdd:COG1196 592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLeaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1090 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Cdd:COG1196 672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 1170 ASEYESLIAKHGTLKSAHKNLE--------------VEHKDLEDRYNQLLKQKgqlEDLEKTLK 1219
Cdd:COG1196 752 ALEELPEPPDLEELERELERLEreiealgpvnllaiEEYEELEERYDFLSEQR---EDLEEARE 812
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-839 |
5.34e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 91.28 E-value: 5.34e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 136 QKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQwmEVTDMSQEEIEPLLKNMVLHLKRLIDERDEHSETIIELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI--AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 216 EERDGLhfpphasssaqspcGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEN 295
Cdd:TIGR02169 350 KRRDKL--------------TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 296 MNLLSDARSARMyrdELDALREKavrVDKLESEVsrykerlhdiefyKARVEELKEDNQVLLETKTMLEDQLEGTRARSD 375
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAK---INELEEEK-------------EDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 376 KLHELEKENLQLKAKLHDMEMERD------MDRKKIEELMEENMT---LEMAQKQSMDESLHLGWEL------------- 433
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARaseervRGGRAVEEVLKASIQgvhGTVAQLGSVGERYATAIEVaagnrlnnvvved 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 434 -------------EQISRTSEL------SEAPQKSLGHE------------------------------VNELTSS---- 460
Cdd:TIGR02169 557 davakeaiellkrRKAGRATFLplnkmrDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdtlvVEDIEAArrlm 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 461 ---RLLKLE---------MENQSLTKTVEELRSTMDSAE--GTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQN 526
Cdd:TIGR02169 637 gkyRMVTLEgelfeksgaMTGGSRAPRGGILFSRSEPAElqRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 527 LSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKET 599
Cdd:TIGR02169 717 KIGEIEKEIEQLEQEEEKLKErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEI 796
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 600 SSKLSKIEFEKRQIRKelehykekgeRAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTL 679
Cdd:TIGR02169 797 QAELSKLEEEVSRIEA----------RLREIEQKLNRLTLEKEYLEKEIQELQ---EQRIDLKEQIKSIEKEIENLNGKK 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 680 DSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQ 759
Cdd:TIGR02169 864 EELEE---ELEELEAALRDLESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 760 GLDTENQRLQKA---LENSNKKIQQLESELQDLEMENqtlQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR02169 938 DPKGEDEEIPEEelsLEDVQAELQRVEEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
|
...
gi 1378869096 837 ENK 839
Cdd:TIGR02169 1015 KKR 1017
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1072 |
1.07e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 86.91 E-value: 1.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 497 EKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEhykekgERAEELENELHHLEKENELLQKKITNLKIT 654
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE------EAEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 655 CEKIEALEQENSELERENRKYKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEK 734
Cdd:COG1196 378 EEELEELAEELLEALRAAAELAAQL---EELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 735 EQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQT--LQKNLEELKISSKRLEQ 812
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 813 LEKENKSLEQ---------------ETSQLEKDKKQLEKENKRLR----QQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:COG1196 529 LIGVEAAYEAaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 874 GIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 954 KLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT-VKKNYEALKQRQDEEKMVQSSPPVSGEDNKWERE 1032
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAErEELLEELLEEEELLEEEALEELPEPPDLEELERE 768
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1378869096 1033 SQETTRELlkvkDRLIEVernN-------ATLQAEKQALKTQLKQLE 1072
Cdd:COG1196 769 LERLEREI----EALGPV---NllaieeyEELEERYDFLSEQREDLE 808
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
3.39e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 77.67 E-value: 3.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKSESQ----RVNKKVNNDASLRIHNLSILVRQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 91 QETL-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-836 |
3.76e-16 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 84.69 E-value: 3.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESEVSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRT-----SELSEAPQK--SLGHEVNELTSSrLLKLEMENQSL 472
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKleeiqNQISQNNKIisQLNEQISQLKKE-LTNSESENSEK 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 473 TKTVEElrstmdsaegTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQ 552
Cdd:TIGR04523 362 QRELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKE 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 553 IKILEQENEHLNQTVSSLRqrSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELehyKEKGERAEELE 631
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLT--NQDSVkELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLN 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 632 NELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTLDSfKNLTFQLESLEKENSQLDEENLELRRNVE 711
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQK 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 712 SLKcasMKMAQLQLENKELESEKEQLKKGLELMKASF----KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:TIGR04523 579 SLK---KKQEEKQELIDQKEKEKKDLIKEIEEKEKKIssleKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 788 -------DLEMENQTLQKNLEEL---------------------KISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 656 eirnkwpEIIKKIKESKTKIDDIielmkdwlkelslhykkyitrMIRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1096 |
5.87e-16 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 84.71 E-value: 5.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 256 AKAKIRRLRQELEEKTEQLLDCKQELEQ-----MEIELKRLQQENmNLLSDARSARMYRDELDALREKAVRVDKLESEVS 330
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQykekaCEIRDQITSKEA-QLESSREIVKSYENELDPLKNRLKEIEHNLSKIM 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 331 RYKERLHDIEFYKARVEELKED-NQVLLETKTMLEDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEEL 408
Cdd:TIGR00606 266 KLDNEIKALKSRKKQMEKDNSElELKMEKVFQGTDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTEL 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 409 MEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH-EVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAE 487
Cdd:TIGR00606 346 LVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 488 GTTSKI--------LKIEKENQRLSKKVEILENEIIQekqsLQNCQNLSKDLMKEKAQLEKTIETL---RENS------- 549
Cdd:TIGR00606 426 EQADEIrdekkglgRTIELKKEILEKKQEELKFVIKE----LQQLEGSSDRILELDQELRKAERELskaEKNSltetlkk 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 550 ------------ERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESI-------KETSSKLSK 605
Cdd:TIGR00606 502 evkslqnekadlDRKLRKLDQEMEQLNHHTTTRTQmemltKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkKQLEDWLHS 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 606 IEFEKRQIRKELEHYKEKGERAEELEnelHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKT------L 679
Cdd:TIGR00606 582 KSKEINQTRDRLAKLNKELASLEQNK---NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSskqramL 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 680 DSFKNLTFQ-LESLEKENS----------QLDEENLELRRNVES-LKCASMKMAQLQLENKELESEKEQLkKGLELMKAS 747
Cdd:TIGR00606 659 AGATAVYSQfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEM-LGLAPGRQS 737
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 748 F-----KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ---DLEMENQTLQKNLEELKISSKRLEQLEKENKS 819
Cdd:TIGR00606 738 IidlkeKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQG 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 820 --LEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRA 897
Cdd:TIGR00606 818 sdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEV 897
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 898 TIDIKTLVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY-KLLESKLESTLKKSLEIKEE 973
Cdd:TIGR00606 898 QSLIREIKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYmKDIENKIQDGKDDYLKQKET 977
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRqdeEKMVQSSPPVSGEDNKWeRESQETTRELLKV--KDRLIEVE 1051
Cdd:TIGR00606 978 ELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENEL-KEVEEELKQHLKEmgQMQVLQMK 1053
|
890 900 910 920
....*....|....*....|....*....|....*....|....*
gi 1378869096 1052 RNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1096
Cdd:TIGR00606 1054 QEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1256 |
7.13e-16 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 84.07 E-value: 7.13e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSD-ARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEkNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 341 fykARVEELKEDNQVLL-ETKTM------LEDQLEGTRARSDKLHeLEKENLQLKAK--------LHDMEMERDMDRKKI 405
Cdd:pfam01576 82 ---SRLEEEEERSQQLQnEKKKMqqhiqdLEEQLDEEEAARQKLQ-LEKVTTEAKIKkleedillLEDQNSKLSKERKLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 406 EE--------LMEENMTLEMAQK-----QSMDESLHLGWELEQISRtSELSEAPQKSLGH--EVNELTSSRLLKLEMENQ 470
Cdd:pfam01576 158 EEriseftsnLAEEEEKAKSLSKlknkhEAMISDLEERLKKEEKGR-QELEKAKRKLEGEstDLQEQIAELQAQIAELRA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 471 SLTKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKV----EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIET-- 544
Cdd:pfam01576 237 QLAKKEEELQAALARLEEETAQKNNALKKIRELEAQIselqEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTta 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 545 ----LRENSERQI----KILEQENEHLNQTVSSLRQ-----------------RSQISAEARVKDIEKENKILHESIKET 599
Cdd:pfam01576 317 aqqeLRSKREQEVtelkKALEEETRSHEAQLQEMRQkhtqaleelteqleqakRNKANLEKAKQALESENAELQAELRTL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 600 SSKLSKIEFEKRQIRKELE-----------HYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668
Cdd:pfam01576 397 QQAKQDSEHKRKKLEGQLQelqarlseserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQEL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 669 ERENRKYKktldsfKNLTFQLESLEKENSQLDE---ENLELRRNVEslKCASMKMAQLQLENKELESEKEQLKKGLELMK 745
Cdd:pfam01576 477 LQEETRQK------LNLSTRLRQLEDERNSLQEqleEEEEAKRNVE--RQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 746 ASFKKTERL-------EVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNL-EELKISSKRLEQ----- 812
Cdd:pfam01576 549 RLQRELEALtqqleekAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLaEEKAISARYAEErdrae 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 813 ---LEKENK--SLEQETSQLEKDKKQLEKENKRLRqqAEIKDTTLEENNV--KIGNLEKENKTLFKEIGIYKEsciRLKE 885
Cdd:pfam01576 629 aeaREKETRalSLARALEEALEAKEELERTNKQLR--AEMEDLVSSKDDVgkNVHELERSKRALEQQVEEMKT---QLEE 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 886 LEKEnkelvKRATIDIKtlvtLREDLVSEKLKTQqmnndLEKLTHELEKIGLNKERLLHD-----EQSTDDRYKLLESKL 960
Cdd:pfam01576 704 LEDE-----LQATEDAK----LRLEVNMQALKAQ-----FERDLQARDEQGEEKRRQLVKqvrelEAELEDERKQRAQAV 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 961 ESTLKKSLEIKEekiaaLEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSPPVSGEDNkwERESQETTREL 1040
Cdd:pfam01576 770 AAKKKLELDLKE-----LEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKES--EKKLKNLEAEL 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1041 LKVKDRLIEVER---------------------NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTL 1099
Cdd:pfam01576 843 LQLQEDLAASERarrqaqqerdeladeiasgasGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQL 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1100 QTQnakLQVENSTLNSQSTS---LMNQNAQLLIQQSSLENENESviKEREDLKSLYDSLIKDHEKLELLHERQASEYESL 1176
Cdd:pfam01576 923 TTE---LAAERSTSQKSESArqqLERQNKELKAKLQEMEGTVKS--KFKSSIAALEAKIAQLEEQLEQESRERQAANKLV 997
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1177 IAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQL 1256
Cdd:pfam01576 998 RRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTL 1077
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
252-943 |
8.40e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.83 E-value: 8.40e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLldckqeleqmeielKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESEVSR 331
Cdd:COG1196 180 KLEATEENLERLEDILGELERQL--------------EPLERQ-------AEKAERYR----ELKEELKELE-AELLLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 332 YKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 412 NMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEgtts 491
Cdd:COG1196 311 RRELEERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE---- 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 492 KILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 572 QRSQISAEARVKDIEKENKILHESIKEtSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 652 KITCEKIEALEQENSELERENRKYKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRN------VESLKCASMKMAQL 723
Cdd:COG1196 539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVL 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 724 QLENKELESEKEQLKKGLELMKASfkkTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLFKEIGIYKEs 879
Cdd:COG1196 696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER- 774
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 880 ciRLKELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 775 --EIEALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
313-844 |
1.34e-15 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 83.17 E-value: 1.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 313 DALREKAVRVDKLESEVSRYKER-LHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:PRK02224 180 RVLSDQRGSLDQLKAQIEEKEEKdLHErlngleseLAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDEslhlgweleqisrtSELSEAPQKSLghevneltSSRLL 463
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE--------------AGLDDADAEAV--------EARRE 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 464 KLEMENQSLTKTVEELR----STMDSAEGTTSKILKIEKENQRLSKKVEILENEiiqekqsLQNCQNLSKDLMKEKAQLE 539
Cdd:PRK02224 318 ELEDRDEELRDRLEECRvaaqAHNEEAESLREDADDLEERAEELREEAAELESE-------LEEAREAVEDRREEIEELE 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 540 KTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEK---ENKILHE------------------S 595
Cdd:PRK02224 391 EEIEELRErfgDAPVDLGNAEDFLEELREERDELREREA-ELEATLRTARErveEAEALLEagkcpecgqpvegsphveT 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 596 IKETSSKLSKIEFEKRQIRKELEHYKEKGERAEEL---ENELHHLEKENELLQKKITNLKITC----EKIEALEQENSEL 668
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAERRETIeekrERAEELRERAAEL 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 669 ERENRKYK-----------------KTLDSFK-NLTFQLESLEKENSQLDEENlELRRNVESLKCASMKMAQLQLENKEL 730
Cdd:PRK02224 550 EAEAEEKReaaaeaeeeaeeareevAELNSKLaELKERIESLERIRTLLAAIA-DAEDEIERLREKREALAELNDERRER 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 731 ESEKEQLKKGLElmkASFKKtERLEvsyqGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL 810
Cdd:PRK02224 629 LAEKRERKRELE---AEFDE-ARIE----EAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERR 700
|
570 580 590
....*....|....*....|....*....|....*..
gi 1378869096 811 EQLEKENKSLE---QETSQLEKDKKQLEKEnkrLRQQ 844
Cdd:PRK02224 701 EALENRVEALEalyDEAEELESMYGDLRAE---LRQR 734
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1317 |
1.80e-15 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 82.86 E-value: 1.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKLSKIEFEKR---QIRKELEHYKEkgERAEELEN 632
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDamaDIRRRESQSQE--DLRNQLQN 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 633 ELHHLEKENELLQKKITNLKITCEKI-------EALEQENS----ELERENRKYKKTLDSFKNLTFQ---------LESL 692
Cdd:pfam15921 150 TVHELEAAKCLKEDMLEDSNTQIEQLrkmmlshEGVLQEIRsilvDFEEASGKKIYEHDSMSTMHFRslgsaiskiLREL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 693 EKENSQLDEENLELRRNVESLKCASMKMAQLQLEN-----KELESEKEQLKKGLelmkasfkkTERLEVSYQGLDTENQR 767
Cdd:pfam15921 230 DTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQhqdriEQLISEHEVEITGL---------TEKASSARSQANSIQSQ 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 768 LQKALENSNKKIQQLESELQDLEMENQTLQKNLEELK-ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:pfam15921 301 LEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKrMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 847 ikdttleennVKIGNLEKENKTLfkeigiykescirlkELEKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL 925
Cdd:pfam15921 381 ----------KLLADLHKREKEL---------------SLEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 926 EKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTlKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 1005
Cdd:pfam15921 436 KAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST-KEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEA 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1006 -------LKQRQDEEKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVER----NNATLQAEKQ----ALKTQLKQ 1070
Cdd:pfam15921 515 tnaeitkLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRqqieNMTQLVGQHGrtagAMQVEKAQ 594
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1071 LETQNNNLQaqiLALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKS 1150
Cdd:pfam15921 595 LEKEINDRR---LELQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN 667
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1151 LYDSLIKDHEKLELLHERQASEYESLIAK-HGTLKSAHKNLEVEHKDLEDR--------------YNQLLKQKGQLEDLE 1215
Cdd:pfam15921 668 ELNSLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQ 747
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1216 KTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQY 1295
Cdd:pfam15921 748 SKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDII 827
|
810 820
....*....|....*....|...
gi 1378869096 1296 QQLDITSTKLNNQCEL-LSQLKG 1317
Cdd:pfam15921 828 QRQEQESVRLKLQHTLdVKELQG 850
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
247-834 |
2.85e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.29 E-value: 2.85e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQME--IELKRLQQENMNLLSDARSARmyrdeldaLREKAVRVDK 324
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEaeLEELRLELEELELELEEAQAE--------EYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 325 LESEVSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSD----KLHELEKENLQLKAKLHDMEMERDM 400
Cdd:COG1196 300 LEQDIARLEERRRELE---ERLEELEEELAELEEELEELEEELEELEEELEeaeeELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 401 DRKKIEELMEENMTLEMAQKQSMDESLHLgwELEQISRTSELSEAPQKSLGHEVNELTSsrLLKLEMENQSLTKTVEELR 480
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEEL--EEAEEALLERLERLEEELEELEEALAEL--EEEEEEEEEALEEAAEEEA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 481 STMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKD---------LMKEKAQLEKTIETLRENS-- 549
Cdd:COG1196 453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyegflegvkAALLLAGLRGLAGAVAVLIgv 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 550 ----ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKD----IEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYK 621
Cdd:COG1196 533 eaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 622 EK----GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSfknltfQLESLEKENS 697
Cdd:COG1196 613 ARyyvlGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE------AEAELEELAE 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKA-LENSN 776
Cdd:COG1196 687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPdLEELE 766
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1378869096 777 KKIQQLESELQDL-------EMENQTLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:COG1196 767 RELERLEREIEALgpvnllaIEEYEELEERYDFL---SEQREDLEEARETLEEAIEEIDRETRER 828
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
246-1088 |
4.66e-15 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 81.37 E-value: 4.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMeieLKRLQQEnmnllSDARSArmyrdELDALREkavrvdkL 325
Cdd:pfam01576 210 KRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAA---LARLEEE-----TAQKNN-----ALKKIRE-------L 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 326 ESEVSRYKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEMEr 398
Cdd:pfam01576 270 EAQISELQEDLESERAARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQ- 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 399 DMDRKKIEELMEENMTLEMAQ---------KQSMD-ESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEME 468
Cdd:pfam01576 349 EMRQKHTQALEELTEQLEQAKrnkanlekaKQALEsENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQ 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 469 NQSLTKTVEELRSTMDSAEGTTSkilKIEKENQRLSKKVEILENEiiqekqsLQNCQNLSKDLMKEKAQLEKtieTLREN 548
Cdd:pfam01576 428 RAELAEKLSKLQSELESVSSLLN---EAEGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLST---RLRQL 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 549 SERQIKILEQENEHLNQTVSSLRQRSqiSAEARVKDIEKEnkilhesIKETSSKLSKIEFEKRQIRKELEhykEKGERAE 628
Cdd:pfam01576 495 EDERNSLQEQLEEEEEAKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 629 ELENELHHLEKENELLQKKITNLKItceKIEALEQENSELERENRKYKKTLDSFKNLTFQL---------ESLEKENSQL 699
Cdd:pfam01576 563 EKAAAYDKLEKTKNRLQQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRAL 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 700 D-----EENLELRRNVESlkcaSMKMAQLQLEN------------KELESEKEQLKKGLELMKASFKKTE---------- 752
Cdd:pfam01576 640 SlaralEEALEAKEELER----TNKQLRAEMEDlvsskddvgknvHELERSKRALEQQVEEMKTQLEELEdelqatedak 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 753 -RLEVSYQGLDTENQR-LQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQ 822
Cdd:pfam01576 716 lRLEVNMQALKAQFERdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREE 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 823 ETSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIyKESCIRLKELEKE-------NKE 892
Cdd:pfam01576 796 AVKQLKKLQaqmKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGA 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 893 LVKRATIDIK-----TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLLH----------DEQSTDDRYKL 955
Cdd:pfam01576 875 SGKSALQDEKrrleaRIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTSqksesarqqlERQNKELKAKL 954
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 956 --LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL-KTVKKNYEALKQRQDEEKMVQssppvsgednKWERE 1032
Cdd:pfam01576 955 qeMEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHAD----------QYKDQ 1024
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:pfam01576 1025 AEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
798-1376 |
4.94e-15 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 81.22 E-value: 4.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 798 KNLEELKISSKRLEQLEKENKSLEQETSQLEK-------DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLF 870
Cdd:TIGR04523 30 KQDTEEKQLEKKLKTIKNELKNKEKELKNLDKnlnkdeeKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKIN 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 871 KEIGIYKESCIRLK----ELEKENKELVKRATIDIKTLVTLREDLVSEKLKtqqmNNDLEKLTHELEKIGLNKERLLHDE 946
Cdd:TIGR04523 110 SEIKNDKEQKNKLEvelnKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNK----YNDLKKQKEELENELNLLEKEKLNI 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 947 QSTDDRYKLLESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ-----RQDEEKMVQSSPP 1021
Cdd:TIGR04523 186 QKNIDKIKNKLLKLELLLSN-LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTeisntQTQLNQLKDEQNK 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1022 VSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQA-----LKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1096
Cdd:TIGR04523 265 IKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdwnkeLKSELKNQEKKLEEIQNQISQNNKIISQLNEQI 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1097 TTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESL 1176
Cdd:TIGR04523 345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1177 IAKHGTLKSAHKNLEVEHKDLEDRYNQLlkqKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQL 1256
Cdd:TIGR04523 425 EKEIERLKETIIKNNSEIKDLTNQDSVK---ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL 501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1257 LKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDitsTKLNNQCELLSqlKGNLEEENRHLLDQIQTLMLQ 1336
Cdd:TIGR04523 502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLE---DELNKDDFELK--KENLEKEIDEKNKEIEELKQT 576
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1378869096 1337 NRTLLEQNMESKDLFhveqRQYIDKLNELRRQKEKLEEKI 1376
Cdd:TIGR04523 577 QKSLKKKQEEKQELI----DQKEKEKKDLIKEIEEKEKKI 612
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
5.33e-15 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 74.37 E-value: 5.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVRQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSwfTEAwlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
261-1123 |
1.24e-14 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 80.22 E-value: 1.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARsarmyrDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE------EETAQKNNALKKIRELEAQISELQEDLESER 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 341 FYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEMErDMDRKKIEELMEENM 413
Cdd:pfam01576 285 AARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQ-EMRQKHTQALEELTE 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 414 TLEMAQ---------KQSMD-ESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRSTM 483
Cdd:pfam01576 364 QLEQAKrnkanlekaKQALEsENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEKLSKLQSEL 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 484 DSAEGTTSKIlkiEKENQRLSKKVEILENEiiqekqsLQNCQNLSKDLMKEKAQLEKTietLRENSERQIKILEQENEHL 563
Cdd:pfam01576 443 ESVSSLLNEA---EGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEE 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 564 NQTVSSLRQRSqiSAEARVKDIEKEnkilhesIKETSSKLSKIEFEKRQIRKELEhykEKGERAEELENELHHLEKENEL 643
Cdd:pfam01576 510 EAKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLEEKAAAYDKLEKTKNR 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 644 LQKKITNLKItceKIEALEQENSELERENRKYKKTLDSFKNLTFQL---------ESLEKENSQLD-----EENLELRRN 709
Cdd:pfam01576 578 LQQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALSlaralEEALEAKEE 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 710 VESlkcaSMKMAQLQLEN------------KELESEKEQLKKGLELMKASFKKTE-----------RLEVSYQGLDTENQ 766
Cdd:pfam01576 655 LER----TNKQLRAEMEDlvsskddvgknvHELERSKRALEQQVEEMKTQLEELEdelqatedaklRLEVNMQALKAQFE 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 767 R-LQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEKDK---KQL 834
Cdd:pfam01576 731 RdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDL 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 835 EKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIyKESCIRLKELEKE-------NKELVKRATIDIK----- 902
Cdd:pfam01576 811 QRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQDEKrrlea 889
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 903 TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKigLNKErlLHDEQSTDDRYKLLESKLESTLKKsleikeekiaaLEARL 982
Cdd:pfam01576 890 RIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ--LTTE--LAAERSTSQKSESARQQLERQNKE-----------LKAKL 954
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 983 EEstnYNQQLRQELKTVKKNYEAlKQRQDEEKMVQSSppvsgednkweRESQETTRELLKVKDRLIEVernnaTLQAEKQ 1062
Cdd:pfam01576 955 QE---MEGTVKSKFKSSIAALEA-KIAQLEEQLEQES-----------RERQAANKLVRRTEKKLKEV-----LLQVEDE 1014
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 1063 alKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE-------NSTLNSQSTSLMNQ 1123
Cdd:pfam01576 1015 --RRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRElddatesNESMNREVSTLKSK 1080
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
287-878 |
6.28e-14 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 77.63 E-value: 6.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYkerlhdiefykarVEELKEDNQVLLETKTMLEDQ 366
Cdd:PRK01156 150 QRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSS-------------NLELENIKKQIADDEKSHSIT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMaqkqsmdeslhlgwELEQISRTSELSEap 446
Cdd:PRK01156 217 LKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM--------------ELEKNNYYKELEE-- 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 447 qkslghEVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEGTTSKILKIEkENQRLSKKVEILENEIIQEKQSLQNCQN 526
Cdd:PRK01156 281 ------RHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYH-AIIKKLSVLQKDYNDYIKKKSRYDDLNN 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 527 LSKDLMKEKAQLEKTIETLrENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKilheSIKETSSKLSKI 606
Cdd:PRK01156 354 QILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINV----KLQDISSKVSSL 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 607 EFEKRQIRKELEHYKEK-----------------------------GERAEELENELHHLEKENELLQKKITNLK----- 652
Cdd:PRK01156 429 NQRIRALRENLDELSRNmemlngqsvcpvcgttlgeeksnhiinhyNEKKSRLEEKIREIEIEVKDIDEKIVDLKkrkey 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 653 ITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLE-LRRNVESLKCASMKMAQLQLENkeLE 731
Cdd:PRK01156 509 LESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEdLDSKRTSWLNALAVISLIDIET--NR 586
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 732 SEKEQLKKGLelmKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811
Cdd:PRK01156 587 SRSNEIKKQL---NDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEID 663
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 812 QLEKENKSLEQETSQLEKDKKQLEKE-------NKRLRQQAEIKDTTLEENNVKIGNLEKE---NKTLFKEIGIYKE 878
Cdd:PRK01156 664 SIIPDLKEITSRINDIEDNLKKSRKAlddakanRARLESTIEILRTRINELSDRINDINETlesMKKIKKAIGDLKR 740
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
630-1087 |
8.98e-14 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 76.73 E-value: 8.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 630 LENELHhlEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 709
Cdd:COG4717 47 LLERLE--KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 710 VESLkcasmkmaQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKI-QQLESELQD 788
Cdd:COG4717 125 LQLL--------PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 789 LEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEENN 856
Cdd:COG4717 197 LAEELEELQQRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLSLI 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 857 VKIGN---------------LEKENKTLFKEIGIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Cdd:COG4717 273 LTIAGvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEL 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 922 NNDLEKLTHELEKIGLNKER--LLHDEQSTDDryKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRQELktv 999
Cdd:COG4717 353 LREAEELEEELQLEELEQEIaaLLAEAGVEDE--EELRAALE--QAEEYQELKEELEELEEQLEELLGELEELLEAL--- 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1000 kkNYEALKQRQDEEKMvqssppvsgEDNKWERESQETTRELLKVKDRLIEVERNN--ATLQAEKQALKTQLKQLETQNNN 1077
Cdd:COG4717 426 --DEEELEEELEELEE---------ELEELEEELEELREELAELEAELEQLEEDGelAELLQELEELKAELRELAEEWAA 494
|
490
....*....|
gi 1378869096 1078 LQAQILALQR 1087
Cdd:COG4717 495 LKLALELLEE 504
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1376 |
1.69e-13 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 76.63 E-value: 1.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESEVSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELSEAPQKSLGHEVNELTSSR-----------LLKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKEKdelnkykskisEIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 467 MENQSLTKTV--EELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETSSKLSKIefeKRQIRKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 618 EHYKEKGERAEELENELhhlekENELLQKKITNLKITCE-KIEALEQENSELERENRKYKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 695 ENSQLDEENLELRRNVESLKCA---SMKMAQLQLEN---KELESEKEQLKKGLELMKASFKKTERLEVSYQGLD------ 762
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDfgkeen 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 763 ----TENQRLQKALENSNKKIQQLESELQDLEM-------ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR01612 1107 ikyaDEINKIKDDIKNLDQKIDHHIKALEEIKKksenyidEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKK 1186
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 832 KQLEKENKRLRQQAEI-KD-TTLEE-NNVKIGNLEKENKTLFKEIGIYK---ESCIRLKELEKENKELVKRATIDIKTLV 905
Cdd:TIGR01612 1187 NIYDEIKKLLNEIAEIeKDkTSLEEvKGINLSYGKNLGKLFLEKIDEEKkksEHMIKAMEAYIEDLDEIKEKSPEIENEM 1266
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 906 TLREDLVSEkLKTQQMNNDLEKLTHELEKiglnkerlLHDEQSTDDRYKLLESKLESTLKKSL-EIKEEkiaaLEARLEE 984
Cdd:TIGR01612 1267 GIEMDIKAE-METFNISHDDDKDHHIISK--------KHDENISDIREKSLKIIEDFSEESDInDIKKE----LQKNLLD 1333
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 985 STNYNQQLRQELKTVKKNYEALKQrqdeEKMVQSSPPVSGEDNKWERESQETTRELLKvKDRLIEVERNNATLQAEKQAL 1064
Cdd:TIGR01612 1334 AQKHNSDINLYLNEIANIYNILKL----NKIKKIIDEVKEYTKEIEENNKNIKDELDK-SEKLIKKIKDDINLEECKSKI 1408
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1065 KTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE---NE 1139
Cdd:TIGR01612 1409 ES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATNDhdfNI 1485
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1140 SVIKERED----LKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLK------SAHKNLEVEHKDLEDRYNQLLKQKG 1209
Cdd:TIGR01612 1486 NELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKFILEAE 1565
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1210 QLEdlEKTLKVEQEKMLLKNKNHETVAAEyKKLCGENDRLNHTYNQLLKETevlqtdhkNLKSLLNSSRLEQTRLEAEFS 1289
Cdd:TIGR01612 1566 KSE--QKIKEIKKEKFRIEDDAAKNDKSN-KAAIDIQLSLENFENKFLKIS--------DIKKKINDCLKETESIEKKIS 1634
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1290 KLK--EQYQQLDITSTKLNNQCELLSQLKG---NLEEENRHlLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLN- 1363
Cdd:TIGR01612 1635 SFSidSQDTELKENGDNLNSLQEFLESLKDqkkNIEDKKKE-LDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANk 1713
|
1210
....*....|....
gi 1378869096 1364 -ELRRQKEKLEEKI 1376
Cdd:TIGR01612 1714 eEIESIKELIEPTI 1727
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
540-1250 |
1.97e-13 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 76.16 E-value: 1.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 540 KTIETLRENSERQIKILEQeneHLNQTVSSLRQRSQIsAEARVKDIEKENKILHESIKETSSKLSKIEfEKRQIRKELeh 619
Cdd:TIGR00618 190 KSLHGKAELLTLRSQLLTL---CTPCMPDTYHERKQV-LEKELKHLREALQQTQQSHAYLTQKREAQE-EQLKKQQLL-- 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 620 yKEKGERAEELENELHHLEKENELLQKKITNLKITcEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQL 699
Cdd:TIGR00618 263 -KQLRARIEELRAQEAVLEETQERINRARKAAPLA-AHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 700 DE----------ENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQ--- 766
Cdd:TIGR00618 341 EEqrrllqtlhsQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSafr 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 767 --RLQKALENSNKKIQQLESELQDLEMENQTLQKNLE-----ELKISSKRLEQLEKENKSL---EQETSQLEKDKKQLEK 836
Cdd:TIGR00618 421 dlQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEkihlqESAQSLKEREQQLQTKEQIhlqETRKKAVVLARLLELQ 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 837 ENKRLRQQAEIKdttLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Cdd:TIGR00618 501 EEPCPLCGSCIH---PNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQ 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 917 KTQQMNNDLEKLTHELEKIglnkeRLLHDEQSTDDRYKLLESKLEstlkksLEIKEEKIAALEARLEEStNYNQQLRQEL 996
Cdd:TIGR00618 578 CDNRSKEDIPNLQNITVRL-----QDLTEKLSEAEDMLACEQHAL------LRKLQPEQDLQDVRLHLQ-QCSQELALKL 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 997 KTVKKNYEALKQRQdeekmvqssppvsgednkwERESQETTRELLKVKdrLIEVERNNATLQAEKQALKTQLKQLETQNN 1076
Cdd:TIGR00618 646 TALHALQLTLTQER-------------------VREHALSIRVLPKEL--LASRQLALQKMQSEKEQLTYWKEMLAQCQT 704
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1077 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ-NAQLLIQQSSLENENESVIKEREDLKSLYDSL 1155
Cdd:TIGR00618 705 LLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQaRTVLKARTEAHFNNNEEVTAALQTGAELSHLA 784
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1156 IKDHEKLELLHERQaSEYESLIAKHGT-LKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHET 1234
Cdd:TIGR00618 785 AEIQFFNRLREEDT-HLLKTLEAEIGQeIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQ 863
|
730
....*....|....*.
gi 1378869096 1235 VAAEYKKLCGENDRLN 1250
Cdd:TIGR00618 864 LTQEQAKIIQLSDKLN 879
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1306 |
2.66e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.95 E-value: 2.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKlEMENQSLTKTVEELRSTMDSAEGTTSK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 493 ILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGE---RAEELENELHHLEKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 647 KITNLKITCE------KIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENS-QLDEENLELRRNVESLKcasmK 719
Cdd:PTZ00121 1337 KAEEAKKAAEaakaeaEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEEDKKKADELK----K 1412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 720 MAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQtLQKN 799
Cdd:PTZ00121 1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKK 1491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 800 LEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTtleENNVKIGNLEKENKTLFKEigiyKES 879
Cdd:PTZ00121 1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA---EEKKKADELKKAEELKKAE----EKK 1564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 880 CIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDRYKLLESK 959
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI---KAEELKKAEEEKKKVEQLKKK 1641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 960 LESTLKKSLEIKEE------KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQssppvsgEDNKWERES 1033
Cdd:PTZ00121 1642 EAEEKKKAEELKKAeeenkiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-------ELKKKEAEE 1714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1034 QETTRELLKVKD-RLIEVERNNATLQAEKQALKtQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST 1112
Cdd:PTZ00121 1715 KKKAEELKKAEEeNKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1113 LNSQSTSLMNQNAQLLIQQSSleNENESVIKereDLKSLYDSLIKdheklellherqaseyESLIAKHGTLKSAHKnlev 1192
Cdd:PTZ00121 1794 MEVDKKIKDIFDNFANIIEGG--KEGNLVIN---DSKEMEDSAIK----------------EVADSKNMQLEEADA---- 1848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1193 ehkdledrynqllkqkgqledlektlkVEQEKMllkNKNHETvaaeykklcGENDRLNHTYNqllKETEVLQTDHKNLKS 1272
Cdd:PTZ00121 1849 ---------------------------FEKHKF---NKNNEN---------GEDGNKEADFN---KEKDLKEDDEEEIEE 1886
|
970 980 990
....*....|....*....|....*....|....
gi 1378869096 1273 LLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
Cdd:PTZ00121 1887 ADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLD 1920
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
252-1012 |
2.71e-13 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 75.85 E-value: 2.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMyRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAT-RLELDGFERGPFSERQIKNFHTL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 332 YKERLHDIEFYKAR-VEELKEDNQVLLETKTMLEDQLEGT-RARSDKLHELEKENLQLKAKLHDME-MERDMDR--KKIE 406
Cdd:TIGR00606 399 VIERQEDEAKTAAQlCADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRilELDQ 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 407 ELMEENMTLEMAQKQSMDESL-----HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL--KLEMENQSLTKTVEEL 479
Cdd:TIGR00606 479 ELRKAERELSKAEKNSLTETLkkevkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkDKMDKDEQIRKIKSRH 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 480 RSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------SERQI 553
Cdd:TIGR00606 559 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEE 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 554 KILEQENEHLNQtvsSLRQRSQISAEARVKDiekenKILHESIKETSS------KLSKIEFEKRQIRKELEH-YKEKGER 626
Cdd:TIGR00606 639 SDLERLKEEIEK---SSKQRAMLAGATAVYS-----QFITQLTDENQSccpvcqRVFQTEAELQEFISDLQSkLRLAPDK 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 627 AEELENELHHLEKENELLqkkITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNltfqleSLEKENSQLDEENLEL 706
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEM---LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN------DIEEQETLLGTIMPEE 781
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 707 RrNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASF------KKTERLEVSYQGLDTENQRLQKALENSNKKIQ 780
Cdd:TIGR00606 782 E-SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRtvqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQ 860
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 781 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQ 940
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 861 NLEKENKTLFKEIGIYkescirLKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLnK 939
Cdd:TIGR00606 941 DKVNDIKEKVKNIHGY------MKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI-Q 1013
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 940 ERLLHDEqstddrykLLESKLESTLKkslEIKEEKIAAL----EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:TIGR00606 1014 ERWLQDN--------LTLRKRENELK---EVEEELKQHLkemgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
136-847 |
3.10e-13 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 75.39 E-value: 3.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 136 QKKEEFIERIQGLD-FDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEEIEPL---LKNMVLHLKRLIDERDEHSETI 211
Cdd:TIGR00618 163 KEKKELLMNLFPLDqYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYherKQVLEKELKHLREALQQTQQSH 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 212 IELSEERDGLHfpphASSSAQSPCGSPgMKRTESRQHLSVELADAKAKIRRLRQ--ELEEKTEQLLDCKQELEQMEIELK 289
Cdd:TIGR00618 243 AYLTQKREAQE----EQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIEQQAQRIHTELQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 290 RLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEG 369
Cdd:TIGR00618 318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 370 TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhlgwelEQISRTSELSEAPQKS 449
Cdd:TIGR00618 398 LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ---------CEKLEKIHLQESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 450 LGHEVNELTSSRLLKLEMEnqslTKTVEElrstmdsaegttsKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSK 529
Cdd:TIGR00618 469 KEREQQLQTKEQIHLQETR----KKAVVL-------------ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 530 DLMKEKAQLEKTIETLRE--NSER-QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHqlTSERkQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 607 EFEKRQIRK------ELEHYKEKGERAEELENELHHLEKEN-ELLQKKITN--LKITCEKIEALEQENSELERENRKYKK 677
Cdd:TIGR00618 612 CEQHALLRKlqpeqdLQDVRLHLQQCSQELALKLTALHALQlTLTQERVREhaLSIRVLPKELLASRQLALQKMQSEKEQ 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 678 tldsfknLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKM-----AQLQLENKELESEKEQLKKGL-ELMKASF 748
Cdd:TIGR00618 692 -------LTYWKEMLAQCQTLLRELEthiEEYDREFNEIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHF 764
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 749 KKTERLEVSYQgLDTENQRLQKALENSNKKIQQLESELQDLEMENQT------LQKNLEELKISSKR---LEQLEKENKS 819
Cdd:TIGR00618 765 NNNEEVTAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdeDILNLQCETLVQEEeqfLSRLEEKSAT 843
|
730 740
....*....|....*....|....*...
gi 1378869096 820 LEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:TIGR00618 844 LGEITHQLLKYEECSKQLAQLTQEQAKI 871
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-713 |
3.86e-13 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 75.08 E-value: 3.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 201 IDERDEHSETIIELSEERDGLhfpphasssaqspcgspGMKRTESRQHLSVELADAKAkIRRLRQELEEKTEQlldCKQE 280
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEA-VEARREELEDRDEE---LRDR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 281 LEQMEIELKRLQQENMNLLSDARSArmyRDELDALREKAvrvDKLESEVSRYKErlhDIEFYKARVEELKEDNQVLLETK 360
Cdd:PRK02224 330 LEECRVAAQAHNEEAESLREDADDL---EERAEELREEA---AELESELEEARE---AVEDRREEIEELEEEIEELRERF 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 361 TMLEDQLEGTRARSDKLHElEKENlqlkakLHDMEMERDMDRKKIEELMEENMTLEMAQK-----QSMDESLHLGWELEQ 435
Cdd:PRK02224 401 GDAPVDLGNAEDFLEELRE-ERDE------LREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETIEED 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 436 ISRTSELS------EAPQKSLGHEVNELTSsrLLKLEMENQSL---TKTVEELRStmDSAEGTTSKILKIE---KENQRL 503
Cdd:PRK02224 474 RERVEELEaeledlEEEVEEVEERLERAED--LVEAEDRIERLeerREDLEELIA--ERRETIEEKRERAEelrERAAEL 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 504 SKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIleqenEHLNQTVSSLRQRSQISAEarVK 583
Cdd:PRK02224 550 EAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAI-----ADAEDEIERLREKREALAE--LN 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 584 DIEKEN-KILHESIKETSSKLSKIEFEK-RQIRKELEHYKEKgeraeeLENELHHLEKENELLQKKITNLKITCEKIEAL 661
Cdd:PRK02224 623 DERRERlAEKRERKRELEAEFDEARIEEaREDKERAEEYLEQ------VEEKLDELREERDDLQAEIGAVENELEELEEL 696
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 662 EQENSELerENRKYKktldsfknltfqLESLEKENSQLDEENLELR-----RNVESL 713
Cdd:PRK02224 697 RERREAL--ENRVEA------------LEALYDEAEELESMYGDLRaelrqRNVETL 739
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
481-1236 |
4.45e-13 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 74.76 E-value: 4.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 481 STMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQncqnlskdlmkekaQLEKTIETLRenseRQIKILEQEN 560
Cdd:pfam05483 68 SDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQ--------------ENRKIIEAQR----KAIQELQFEN 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 561 EHLnqtvsSLRQRSQISAEarvKDIEKENK-------ILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENE 633
Cdd:pfam05483 130 EKV-----SLKLEEEIQEN---KDLIKENNatrhlcnLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEE 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 634 LHhLEKENELLQKKItNLKITCEKIEALEQENSElERENRKYKKTL---------DSFKNLTFQLESLEKENSQLDEENl 704
Cdd:pfam05483 202 LR-VQAENARLEMHF-KLKEDHEKIQHLEEEYKK-EINDKEKQVSLlliqitekeNKMKDLTFLLEESRDKANQLEEKT- 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 705 elrrnveslkcasmkmaQLQLEN-KELESEKEQLKKGLELMKASFKKTerleVSYQglDTENQRLQKALENSNKKIQQLE 783
Cdd:pfam05483 278 -----------------KLQDENlKELIEKKDHLTKELEDIKMSLQRS----MSTQ--KALEEDLQIATKTICQLTEEKE 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 784 SELQDLEMENQTLQKNLEELKISSKRLEQLEK-ENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam05483 335 AQMEELNKAKAAHSFVVTEFEATTCSLEELLRtEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIL 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 863 EKENKTLFKEIGIYKEScirlKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKiglnkERL 942
Cdd:pfam05483 415 AEDEKLLDEKKQFEKIA----EELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEK-----EKL 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 943 LHDEQSTDDRYKLLESK--LESTLKKSLEIKEEKiaalearlEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQssp 1020
Cdd:pfam05483 486 KNIELTAHCDKLLLENKelTQEASDMTLELKKHQ--------EDIINCKKQEERMLKQIENLEEKEMNLRDELESVR--- 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1021 pvsgednkweresQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ 1100
Cdd:pfam05483 555 -------------EEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1101 ----TQNAKLQVENSTLNSQSTSL---------MNQNAQLLIQQSSLENENesVIKEREDLKSLYDSLIKDHEKLEL--- 1164
Cdd:pfam05483 622 kkgsAENKQLNAYEIKVNKLELELasakqkfeeIIDNYQKEIEDKKISEEK--LLEEVEKAKAIADEAVKLQKEIDKrcq 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1165 --------LHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYN-QLLKQKGQLEDLEKTLKVE-QEKMLLKNKNHET 1234
Cdd:pfam05483 700 hkiaemvaLMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEiELSNIKAELLSLKKQLEIEkEEKEKLKMEAKEN 779
|
..
gi 1378869096 1235 VA 1236
Cdd:pfam05483 780 TA 781
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
6.93e-13 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 73.57 E-value: 6.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 263 LRQELEEKTEQLL-------DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 395 EMERDMDRKKIEELMEENMTLEMAQKQSMdeslhlgwELEQISRTSELSEAPQKSLGHEVNEL-TSSRLLKLEMENQSLT 473
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQA--------ELSQADALLSPSSDPGDNLAAEIMPAeIREKLIRLQHENKMLR 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 474 KTVE--------ELRSTMDSAEGTTSkilKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETL 545
Cdd:pfam05622 296 LGQEgsyrerltELQQLLEDANRRKN---ELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKL 372
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1378869096 546 RE-NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 373 HEaQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
369-786 |
9.11e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.94 E-value: 9.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 369 GTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQK 448
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 449 SLGHEVNELTSSRLLKLEMENQSLTKTvEELRSTMDSAEgttSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLS 528
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELE---AQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 529 KDLMKEKAQLEKTIETLrensERQIKILEQEnehlnqtvsslrqrsQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Cdd:TIGR02168 827 ESLERRIAATERRLEDL----EEQIEELSED---------------IESLAAEIEELEELIEELESELEALLNERASLEE 887
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 609 EKRQIRKELEhykEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENseLERENRKYKKTLDSFKNLTFQ 688
Cdd:TIGR02168 888 ALALLRSELE---ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENK 962
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 689 LESLEKensqldeenlELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELMKASF----KKTERLEVSYQGLDTE 764
Cdd:TIGR02168 963 IEDDEE----------EARRRLKRLE---NKIKELGPVNLAAIEEYEELKERYDFLTAQKedltEAKETLEEAIEEIDRE 1029
|
410 420
....*....|....*....|...
gi 1378869096 765 -NQRLQKALENSNKKIQQLESEL 786
Cdd:TIGR02168 1030 aRERFKDTFDQVNENFQRVFPKL 1052
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
770-1377 |
1.13e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 73.56 E-value: 1.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 770 KALENSNKKIQQLESELQDLEMENQTLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqaeikd 849
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPEL---REELEKLEKEVKELEELKEEIEELEKELESLEGSKR------- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 850 tTLEEnnvKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKratidiktLVTLREDLVSEKlktqqmnNDLEKLT 929
Cdd:PRK03918 256 -KLEE---KIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK--------LSEFYEEYLDEL-------REIEKRL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 930 HELEKIGLNKERLLHDEQStddryklLESKLESTLKKSLEIKEEKiaaleARLEEStnynQQLRQELKTVKKNYEALKQR 1009
Cdd:PRK03918 317 SRLEEEINGIEERIKELEE-------KEERLEELKKKLKELEKRL-----EELEER----HELYEEAKAKKEELERLKKR 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1010 qdeekmvqssppvsgednKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA--QILALQR 1087
Cdd:PRK03918 381 ------------------LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakGKCPVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1088 QTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENEnesVIKERE--DLKSLYDSLIKDHEKLELL 1165
Cdd:PRK03918 443 RELTEEHRKELLEEYTAEL----KRIEKELKEIEEKERKLRKELRELEKV---LKKESEliKLKELAEQLKELEEKLKKY 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1166 H----ERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRynqllkqKGQLEDLEKTLK-VEQEKMLLKNKNHETVAAEYK 1240
Cdd:PRK03918 516 NleelEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEEL-------KKKLAELEKKLDeLEEELAELLKELEELGFESVE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1241 KLCGENDRLNHTYNQLLKetevlqtdhknLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1320
Cdd:PRK03918 589 ELEERLKELEPFYNEYLE-----------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 1321 EEN----RHLLDQIQTLMLQNRTLLEQNMESKDlfhveqrQYIDKLNELRRQKEKLEEKIM 1377
Cdd:PRK03918 658 EEEyeelREEYLELSRELAGLRAELEELEKRRE-------EIKKTLEKLKEELEEREKAKK 711
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-844 |
2.59e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 72.46 E-value: 2.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 182 SQEEIEPLLKNMVLHLKRLIDErdeHSETIIELSEERDGlhfpphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 259 KIRRLRQEL-----------EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARS--ARMYRDELDALREK------- 318
Cdd:pfam15921 325 TVSQLRSELreakrmyedkiEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKllADLHKREKELSLEKeqnkrlw 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 319 ------AVRVDKLESEVSrykERLHDIEFYKARVEELKEdnqvllETKTMLEDQLEGTRARSDKLHELEKENLQLkaklh 392
Cdd:pfam15921 405 drdtgnSITIDHLRRELD---DRNMEVQRLEALLKAMKS------ECQGQMERQMAAIQGKNESLEKVSSLTAQL----- 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 393 dmEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELSEApqkslghEVNELTSSRLLKLEmENQSL 472
Cdd:pfam15921 471 --ESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHL 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 473 TKTVEELRSTmdSAEGTTSKILKIEKEnqrlsKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQ 552
Cdd:pfam15921 537 KNEGDHLRNV--QTECEALKLQMAEKD-----KVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQE 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 553 IKILEQENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKekgeraeeleN 632
Cdd:pfam15921 609 FKILKDKKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------N 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 633 ELHHLEKENELLQKKITNlkitceKIEALEQENSELERENRKYKKTLDSFKNltfQLESLEKENSQldeenlelrrnves 712
Cdd:pfam15921 668 ELNSLSEDYEVLKRNFRN------KSEEMETTTNKLKMQLKSAQSELEQTRN---TLKSMEGSDGH-------------- 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 713 lkcaSMKMAQLQleNKELESEKEQLkkglelmkasfkkterlevsyQGLDTENQRLQKALENSNKKIQ-------QLESE 785
Cdd:pfam15921 725 ----AMKVAMGM--QKQITAKRGQI---------------------DALQSKIQFLEEAMTNANKEKHflkeeknKLSQE 777
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 786 LQDLEMENQTLQKNLEELKISSKRL-EQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQ 844
Cdd:pfam15921 778 LSTVATEKNKMAGELEVLRSQERRLkEKVANMEVALDKASLQFAECQdiiQRQEQESVRLKLQ 840
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
3.19e-12 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 66.15 E-value: 3.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVRQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPayfdENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
3.52e-12 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 66.05 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVRQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPswfnEAWLGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 94 L-QQLIMMSLPNVLIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-838 |
3.55e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.48 E-value: 3.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 203 ERDEHSETIIELSEERDGLHFPPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 280 ELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 435 QISRTSELSEAPQKSlghevneltSSRLLKLEMENqsltKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEilenei 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE------ 1544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 515 IQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKEnkilhe 594
Cdd:PTZ00121 1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA------ 1618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 595 siKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRK 674
Cdd:PTZ00121 1619 --KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 675 YKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK--CASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTE 752
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKkeAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRlEQLEKENKSLEqETSQLEKDKK 832
Cdd:PTZ00121 1777 KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK-EVADSKNMQLE-EADAFEKHKF 1854
|
....*.
gi 1378869096 833 QLEKEN 838
Cdd:PTZ00121 1855 NKNNEN 1860
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
513-1030 |
9.76e-12 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 70.15 E-value: 9.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 513 EIIQEKQSLQNCQN----LSKDLMKEKAQLEKTIETLRENSERQIKileqENEHLNQTVSSLRQRSQISAEARVKDIE-- 586
Cdd:pfam05557 3 ELIESKARLSQLQNekkqMELEHKRARIELEKKASALKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAEln 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 587 ----KENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKITCEKI 658
Cdd:pfam05557 79 rlkkKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAElelqSTNSELEELQERLDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 659 EALEQENS-------ELERENRKYKKTLDSFKNLTFQLES---LEKENSQLDEENLELRRNVESlkcasmkmaqlqleNK 728
Cdd:pfam05557 159 EKQQSSLAeaeqrikELEFEIQSQEQDSEIVKNSKSELARipeLEKELERLREHNKHLNENIEN--------------KL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 729 ELESEKEQLKKGLELMKASFKKTERLEVsyqgldtenqrlqkalensnkKIQQLESELQDLEMENQTLQKNLEELKISSK 808
Cdd:pfam05557 225 LLKEEVEDLKRKLEREEKYREEAATLEL---------------------EKEKLEQELQSWVKLAQDTGLNLRSPEDLSR 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 809 RLEQLEKENK-------SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKE--- 878
Cdd:pfam05557 284 RIEQLQQREIvlkeensSLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAile 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 879 --------------SCIRLKELEK-------ENKELVKRATIDIKTLVTLREDLVS-----EKLKTQQMNNDLEKLTHEL 932
Cdd:pfam05557 364 sydkeltmsnyspqLLERIEEAEDmtqkmqaHNEEMEAQLSVAEEELGGYKQQAQTlerelQALRQQESLADPSYSKEEV 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 933 EKIGLNKERLLHDEQSTDDRYKLLESKLES-TLKKSLEIKEEKIaaLEARLEESTNYNQQLRQELKTVKKNYEALKQR-- 1009
Cdd:pfam05557 444 DSLRRKLETLELERQRLREQKNELEMELERrCLQGDYDPKKTKV--LHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLlk 521
|
570 580
....*....|....*....|...
gi 1378869096 1010 --QDEEKMVQSSPPVSGEDNKWE 1030
Cdd:pfam05557 522 klEDDLEQVLRLPETTSTMNFKE 544
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
474-877 |
1.29e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.80 E-value: 1.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 474 KTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSK--DLMKEKAQLEKTIETL------ 545
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELperlee 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 546 -------RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELE 618
Cdd:COG4717 151 leerleeLRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELE 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 619 HYKEKGERAEELEnELHHLE--------------KENELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSFKN 684
Cdd:COG4717 231 QLENELEAAALEE-RLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 685 LTfQLESLEKE--NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLK-KGLELMKASF--KKTERLEVSYQ 759
Cdd:COG4717 310 LP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQlEELEQEIAALlaEAGVEDEEELR 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 760 GLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKnlEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Cdd:COG4717 389 AALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELE---EELEELEEELEELEEELEELREELAELEAELE 463
|
410 420 430
....*....|....*....|....*....|....*...
gi 1378869096 840 RLRqqaeiKDTTLEENNVKIGNLEKENKTLFKEIGIYK 877
Cdd:COG4717 464 QLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-695 |
1.59e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.41 E-value: 1.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 259 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESEVSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 419 QKQSMDESLHLGWELEQISRTSELSeapqkslghevneLTSSRLLKLEMENQSLTKTVEELRSTMDSAEG-----TTSKI 493
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLL-------------LIAAALLALLGLGGSLLSLILTIAGVLFLVLGllallFLLLA 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 494 LKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnQTVSSLRQR 573
Cdd:COG4717 295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEI 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 574 SQISAEARVKDIEKENKIL--HESIKETSSKLSKIEFEKRQIRKELEHYKEKGERaEELENELHHLEKENELLQKKITNL 651
Cdd:COG4717 373 AALLAEAGVEDEEELRAALeqAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEEL 451
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1378869096 652 KitcEKIEALEQENSELERENRkYKKTLDSFKNLTFQLESLEKE 695
Cdd:COG4717 452 R---EELAELEAELEQLEEDGE-LAELLQELEELKAELRELAEE 491
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
568-1009 |
2.02e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.03 E-value: 2.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 568 SSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Cdd:COG4717 45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 648 ITNLKItCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNV-----ESLKCASMKMAQ 722
Cdd:COG4717 125 LQLLPL-YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslateEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 723 LQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQgldtENQRLQKALEnsnkkIQQLESELQDLEMENQTLQKNLEE 802
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAA----LEERLKEARL-----LLLIAAALLALLGLGGSLLSLILT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 803 LK--------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIG 874
Cdd:COG4717 275 IAgvlflvlgLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 875 IYKESC--IRLKELEKENKELVKRAtiDIKTLVTLREdLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL--HDEQSTD 950
Cdd:COG4717 355 EAEELEeeLQLEELEQEIAALLAEA--GVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLeaLDEEELE 431
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 951 DRYKLLESKLEStLKKSLEIKEEKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4717 432 EELEELEEELEE-LEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1035-1370 |
2.16e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.58 E-value: 2.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1035 ETTRE-LLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnlqAQILALQRQTVSLQeqnttLQTQNAKLQ 1107
Cdd:COG1196 182 EATEEnLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-------AELLLLKLRELEAE-----LEELEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1108 VENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAkhgtlksAH 1187
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE-------LE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1188 KNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDH 1267
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1268 KNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmLQNRTLLEQNMES 1347
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAE 481
|
330 340
....*....|....*....|...
gi 1378869096 1348 KDLFHVEQRQYIDKLNELRRQKE 1370
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYE 504
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
881-1343 |
3.83e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 68.26 E-value: 3.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 881 IRLKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKT---QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:COG4717 46 MLLERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 954 KLLESKLE-STLKKSLEIKEEKIAALEARLEEStnynQQLRQELKTVKKNYEALKQRQDEEKMVQSsppvsgedNKWERE 1032
Cdd:COG4717 126 QLLPLYQElEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLS--------LATEEE 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQnnnlqaqiLALQRQTVSLQEQNTTLQTQNAKLQVENST 1112
Cdd:COG4717 194 LQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE--------LEAAALEERLKEARLLLLIAAALLALLGLG 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1113 LNSQSTSLMNQNAQLLIQQSSLeneneSVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEV 1192
Cdd:COG4717 266 GSLLSLILTIAGVLFLVLGLLA-----LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1193 EHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRlnhtYNQLLKETEVLQTDHKNLKS 1272
Cdd:COG4717 341 ELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEE----YQELKEELEELEEQLEELLG 416
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1378869096 1273 LLN--SSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENR--HLLDQIQTLMLQNRTLLEQ 1343
Cdd:COG4717 417 ELEelLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEE 491
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
252-986 |
5.65e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.82 E-value: 5.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESEVS 330
Cdd:pfam05483 100 ELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLkETCARSAEKTKKYEYERE 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 331 RYKERLHDIE---------FYKARVE----------ELKEDNQVLLETKTMLEDQLEGTRARSDKL--HELEKENlqlka 389
Cdd:pfam05483 180 ETRQVYMDLNnniekmilaFEELRVQaenarlemhfKLKEDHEKIQHLEEEYKKEINDKEKQVSLLliQITEKEN----- 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 390 KLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEvneltssrllkLEMEN 469
Cdd:pfam05483 255 KMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEED-----------LQIAT 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 470 QSLTKTVEELRSTMDSAEGTTSKILKIEKEnqrLSKKVEILENEIIQEKQSLqncqnlskdlmkekaqlektietlrENS 549
Cdd:pfam05483 324 KTICQLTEEKEAQMEELNKAKAAHSFVVTE---FEATTCSLEELLRTEQQRL-------------------------EKN 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 550 ERQIKILEQEnehLNQTVSSLRQRSQISAEARVkDIEKENKILHESiketssklSKIEFEKRQIRKELEHYKEKgerAEE 629
Cdd:pfam05483 376 EDQLKIITME---LQKKSSELEEMTKFKNNKEV-ELEELKKILAED--------EKLLDEKKQFEKIAEELKGK---EQE 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 630 LENELHHLEKENELLQKKITNLKiTCEKIEALEQENSELERENRKYKKTldsfkNLTFQLESLEKENSQLDEEN----LE 705
Cdd:pfam05483 441 LIFLLQAREKEIHDLEIQLTAIK-TSEEHYLKEVEDLKTELEKEKLKNI-----ELTAHCDKLLLENKELTQEAsdmtLE 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKkterlevsyQGLDTENQRLQKALENSnkkiQQLESE 785
Cdd:pfam05483 515 LKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFI---------QKGDEVKCKLDKSEENA----RSIEYE 581
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 786 LQDLEMENQTLQKNLEELKisskrlEQLEKENKSLEqetsqlekdkkQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:pfam05483 582 VLKKEKQMKILENKCNNLK------KQIENKNKNIE-----------ELHQENKALKKKGSAENKQLNAYEIKVNKLELE 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 866 ---NKTLFKEIGIYKESCIRLKELEKEN-KELVKRATIDIKTLVTLREDLVSE-KLKTQQMNNDLEKLTHELEKIGLNKE 940
Cdd:pfam05483 645 lasAKQKFEEIIDNYQKEIEDKKISEEKlLEEVEKAKAIADEAVKLQKEIDKRcQHKIAEMVALMEKHKHQYDKIIEERD 724
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 941 RLLHDEQSTDDRYKLLESKLES----------TLKKSLEIKEEKIAALEARLEEST 986
Cdd:pfam05483 725 SELGLYKNKEQEQSSAKAALEIelsnikaellSLKKQLEIEKEEKEKLKMEAKENT 780
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
264-854 |
5.71e-11 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 67.84 E-value: 5.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDarSARMYRDELDALREKAVRVDKLESEVSRYKERLHD-IEFY 342
Cdd:pfam05557 1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASA--LKRQLDRESDRNQELQKRIRLLEKREAEAEEALREqAELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHEL----EKENLQLKAKLHDME--MER-DMDRKKIEELMEENMTL 415
Cdd:pfam05557 79 RLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELrrqiQRAELELQSTNSELEelQERlDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 416 EMAQKQSMDESLH---LGWELEQISRTSELSEAPQKSLGhEVNELtSSRLLKLEMENQSLTKT----------VEELRST 482
Cdd:pfam05557 159 EKQQSSLAEAEQRikeLEFEIQSQEQDSEIVKNSKSELA-RIPEL-EKELERLREHNKHLNENienklllkeeVEDLKRK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 483 MDSAEGTTSKILKIEKENQRLSKKVEILENeIIQEkqslqNCQNLSK--DLMKEKAQLEKTIETLREnserQIKILEQEN 560
Cdd:pfam05557 237 LEREEKYREEAATLELEKEKLEQELQSWVK-LAQD-----TGLNLRSpeDLSRRIEQLQQREIVLKE----ENSSLTSSA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 561 EHLNQTVSSLRQRSQIsAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKE 640
Cdd:pfam05557 307 RQLEKARRELEQELAQ-YLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQLLERIEEA 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 641 NELLQKkitnlkiTCEKIEALEQENSELERENRKYKKTLDSfknLTFQLESLEKENSQldEENLELRRNVESLKcasMKM 720
Cdd:pfam05557 386 EDMTQK-------MQAHNEEMEAQLSVAEEELGGYKQQAQT---LERELQALRQQESL--ADPSYSKEEVDSLR---RKL 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 721 AQLQLENKELESEKEQLKkgLELMKASFKkterlevsyQGLDTENQR-LQKALENSNKKIQQLESELQDLEMENQTLQKN 799
Cdd:pfam05557 451 ETLELERQRLREQKNELE--MELERRCLQ---------GDYDPKKTKvLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRL 519
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 800 LEELKISSKRLEQLEKENKSL-EQETSQLekdKKQLEKENKRLRQQAEIKDTTLEE 854
Cdd:pfam05557 520 LKKLEDDLEQVLRLPETTSTMnFKEVLDL---RKELESAELKNQRLKEVFQAKIQE 572
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
688-1217 |
9.79e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 67.37 E-value: 9.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 688 QLESLEKENSQLDEENLelrrnVESLKCASMKMAQLQLENKELESEKEQLKKGLElmkasfKKTERLEvSYQGLDTENQR 767
Cdd:PRK02224 188 SLDQLKAQIEEKEEKDL-----HERLNGLESELAELDEEIERYEEQREQARETRD------EADEVLE-EHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 768 LQKALENSNKKIQQLESELQDLEMENQTLQKNLEEL------------------KISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELeeerddllaeaglddadaEAVEARREELEDRDEELRDRLEECRV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKEsciRLKELEKENKELVKR---ATIDIKTLVT 906
Cdd:PRK02224 336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE---EIEELEEEIEELRERfgdAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL----------------HDEQSTDDRYKL--LESKLEStLKKSL 968
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecgqpvegspHVETIEEDRERVeeLEAELED-LEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 969 EIKEEKIAALEArLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSppVSGEDNKWERESQETTRELLKVKDRLI 1048
Cdd:PRK02224 492 EEVEERLERAED-LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE--LRERAAELEAEAEEKREAAAEAEEEAE 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1049 EVERNNATLQAEKQALKTQLKQLETQnNNLQAQILALQRQTVSLQEQNTTLQTQNAKlqvENSTLNSQSTSlmnqnaqll 1128
Cdd:PRK02224 569 EAREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDE---RRERLAEKRER--------- 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1129 IQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQaseyESLIAKHGTLKSAHKNLEV---EHKDLEDRYNQLL 1205
Cdd:PRK02224 636 KRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREER----DDLQAEIGAVENELEELEElreRREALENRVEALE 711
|
570
....*....|..
gi 1378869096 1206 KQKGQLEDLEKT 1217
Cdd:PRK02224 712 ALYDEAEELESM 723
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
957-1287 |
1.19e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.88 E-value: 1.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 957 ESKLESTlkksleikEEKIAALEARLEEstnynqqLRQELKTVKK------NYEALKQRQDE-EKMVQSSppvsgEDNKW 1029
Cdd:COG1196 178 ERKLEAT--------EENLERLEDILGE-------LERQLEPLERqaekaeRYRELKEELKElEAELLLL-----KLREL 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNTTLQTQ 1102
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRRELEER 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1103 NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGT 1182
Cdd:COG1196 318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1183 LKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKmllKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEV 1262
Cdd:COG1196 398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE---EEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474
|
330 340
....*....|....*....|....*
gi 1378869096 1263 LQTDHKNLKSLLNSSRLEQTRLEAE 1287
Cdd:COG1196 475 LEAALAELLEELAEAAARLLLLLEA 499
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
241-570 |
1.25e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.02 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 241 KRTESRQH---LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsdarsarmYRDELDALRE 317
Cdd:TIGR02169 696 ELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 318 kavRVDKLESEVSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL 391
Cdd:TIGR02169 766 ---RIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQR 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Cdd:TIGR02169 843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 472 LTK---------TVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILE---NEIIQEKQSLQNCQNLSKD----LMKEK 535
Cdd:TIGR02169 923 KAKlealeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEER 1002
|
330 340 350
....*....|....*....|....*....|....*..
gi 1378869096 536 AQLEKTIETLrENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1003 KAILERIEEY-EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
506-873 |
2.26e-10 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 65.30 E-value: 2.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 506 KVEILENEiiqekqsLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585
Cdd:pfam07888 28 RAELLQNR-------LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 586 E--KENKILHESIKETSSKLSKIEFEKRQIRKELEH-YKEKGERAEELENELHHLEKEnellQKKITNLKitcekiealE 662
Cdd:pfam07888 101 EkyKELSASSEELSEEKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------K 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 663 QENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLE 742
Cdd:pfam07888 168 EEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 743 LMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEM-----------ENQTLQKNLEELKISSKRL- 810
Cdd:pfam07888 245 RLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLs 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:pfam07888 325 AELQRLEERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
594-816 |
5.23e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 63.63 E-value: 5.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 594 ESIKETSSKLSKIEFEKRQIRKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENR 673
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE---EKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 674 KYKKTLDSFKN-LTFQLESLEKENSQldeENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKAS----F 748
Cdd:COG4942 94 ELRAELEAQKEeLAELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALraelE 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 749 KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE 816
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
592-1179 |
9.40e-10 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 64.33 E-value: 9.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 592 LHESIKETSSKLSKIEFEKRQIRKELEhYKEKGERAEELENE-LHHLEKENELLQKKITNLKitceKIEALEQENSELER 670
Cdd:COG5022 805 LLGSRKEYRSYLACIIKLQKTIKREKK-LRETEEVEFSLKAEvLIQKFGRSLKAKKRFSLLK----KETIYLQSAQRVEL 879
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 671 ENRKYKKTLDSFKNLTfqleSLEKENSQLDEENLELRRNVESLKcasmkMAQLQLENKELESEKE-----QLKKGLELMK 745
Cdd:COG5022 880 AERQLQELKIDVKSIS----SLKLVNLELESEIIELKKSLSSDL-----IENLEFKTELIARLKKllnniDLEEGPSIEY 950
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 746 ASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQK---NLEELKISSKRLEQLEKENKSLEQ 822
Cdd:COG5022 951 VKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAElskQYGALQESTKQLKELPVEVAELQS 1030
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 823 ETSQL--EKDKKQLEKENKRLRQQAEIKDTTLEEnNVKIGNLEKENKTLFK------EIGIYKESCIRLKELEKENKELV 894
Cdd:COG5022 1031 ASKIIssESTELSILKPLQKLKGLLLLENNQLQA-RYKALKLRRENSLLDDkqlyqlESTENLLKTINVKDLEVTNRNLV 1109
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 895 KRATIDIKTL-VTLREDLVSEKLK--------TQQMNNDLEKLTHELEKIG--LNKERLLHdeqstddrYKLLESKLEST 963
Cdd:COG5022 1110 KPANVLQFIVaQMIKLNLLQEISKflsqlvntLEPVFQKLSVLQLELDGLFweANLEALPS--------PPPFAALSEKR 1181
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 964 LKKSleikeekiAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQS--------SPPVSGEDNKWERESQE 1035
Cdd:COG5022 1182 LYQS--------ALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISegwvpteySTSLKGFNNLNKKFDTP 1253
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1036 TTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQ-----EQNTTLQtQNAKLQVEN 1110
Cdd:COG5022 1254 ASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKsatevNYNSEEL-DDWCREFEI 1332
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 1111 STLNSQSTSLMnQNAQLLiqqsslenenESVIKEREDLKSLYDSL--IKDHEKLELLHERQASEYESLIAK 1179
Cdd:COG5022 1333 SDVDEELEELI-QAVKVL----------QLLKDDLNKLDELLDACysLNPAEIQNLKSRYDPADKENNLPK 1392
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
436-1381 |
1.00e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.39 E-value: 1.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 436 ISRTSELSEapqksLGHEVNELTSSRLLKLEMENQSLTKTveELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEII 515
Cdd:PTZ00121 1026 IEKIEELTE-----YGNNDDVLKEKDIIDEDIDGNHEGKA--EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFG 1098
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENkilhES 595
Cdd:PTZ00121 1099 KAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA----ED 1174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 596 IKETSSKLSKIEFEK-RQIRKELEHYKEKGERAEELENELHHLEKENEllQKKITNLKITCE-KIEALEQENSELERENR 673
Cdd:PTZ00121 1175 AKKAEAARKAEEVRKaEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVKKAEEaKKDAEEAKKAEEERNNE 1252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 674 KYKKTLDSFKNLTFQLESLEKENSQLDEEnlELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKasfkKTER 753
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIKAEEARKAD--ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK----KAEE 1326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 754 LEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 834 LEkenkrlrqqaEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVS 913
Cdd:PTZ00121 1407 AD----------ELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK 1476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 914 EKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSleikEEKIAALEARLEESTNYNQQLR 993
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA----EEAKKADEAKKAEEKKKADELK 1552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 994 --QELKT---VKKNYEALKQRQDEEKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVERnNATLQAEKQALKTQL 1068
Cdd:PTZ00121 1553 kaEELKKaeeKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE-EAKIKAEELKKAEEE 1631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1069 KQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL---MNQNAQLLIQQSSLENENESVIKER 1145
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAeedEKKAAEALKKEAEEAKKAEELKKKE 1711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1146 EDLKSLYDSLIKDHE--KLELLHERQASEYESLIAKHGTLKSAHKNlEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQE 1223
Cdd:PTZ00121 1712 AEEKKKAEELKKAEEenKIKAEEAKKEAEEDKKKAEEAKKDEEEKK-KIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDE 1790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1224 KMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTdhKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITST 1303
Cdd:PTZ00121 1791 KRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAI--KEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEA 1868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1304 KLNNQCELLSQLKGNLEE--ENRHLLDQIQTLMLQNRTLLEQNMESKDlfhveqrQYIDKLNELRRQKEKLEEKIMDQYK 1381
Cdd:PTZ00121 1869 DFNKEKDLKEDDEEEIEEadEIEKIDKDDIEREIPNNNMAGKNNDIID-------DKLDKDEYIKRDAEETREEIIKISK 1941
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1316 |
1.16e-09 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 63.77 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 725 LENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeikdttlEENNVKIGNLEKENKTLFKEIGIYKESCIRLK 884
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELE-------ERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 885 ELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD---DRYKLLESKLE 961
Cdd:PRK01156 312 QILSNIDAEINKYHAIIKKLSVLQKDY-NDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKkkiEEYSKNIERMS 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 962 STLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE--EKMV----QSSPPVSGE---DNKWERE 1032
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDElsRNMEmlngQSVCPVCGTtlgEEKSNHI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN-----------LQAQILALQRQTVSLQEQNT---T 1098
Cdd:PRK01156 471 INHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINksineynkiesARADLEDIKIKINELKDKHDkyeE 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1099 LQTQNAKLQVENstLNSQSTSLMNQNAQLliqqSSLENENesVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIa 1178
Cdd:PRK01156 551 IKNRYKSLKLED--LDSKRTSWLNALAVI----SLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSI- 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1179 khgtlksahKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKveqekmllknknhetvaaEYKKLCGENDRLNHTYNQLLK 1258
Cdd:PRK01156 622 ---------REIENEANNLNNKYNEIQENKILIEKLRGKID------------------NYKKQIAEIDSIIPDLKEITS 674
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 1259 ETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK 1316
Cdd:PRK01156 675 RINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIK 732
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
1.70e-09 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 58.32 E-value: 1.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVRQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSwfDESwlSRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1378869096 94 L-QQLIMMSLPNVliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1147 |
1.72e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 62.09 E-value: 1.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 997 KTVKKNYEALKQRQdeEKMVQSSPP---VSGEDnkweresqettreLLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1073
Cdd:COG4942 100 EAQKEELAELLRAL--YRLGRQPPLallLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 1074 QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
658-1173 |
1.74e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.86 E-value: 1.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 658 IEALEQENSELerenrkYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Cdd:COG4717 48 LERLEKEADEL------FKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 738 KKGLELMKAsFKKTERLEVSYQGLDTENQRLQKALENsnkkIQQLESELQDLEMENQTLQKNLEELKISS-----KRLEQ 812
Cdd:COG4717 122 EKLLQLLPL-YQELEALEAELAELPERLEELEERLEE----LRELEEELEELEAELAELQEELEELLEQLslateEELQD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQaeIKDTTLEENNVKIGNLEKENKTLFKEIGIykescirLKELEKENKE 892
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEAQEELEELEEE--LEQLENELEAAALEERLKEARLLLLIAAA-------LLALLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 893 LVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESklesTLKKSLEIKE 972
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPD----LSPEELLELL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 973 EKIAALEARLEESTNYNQQLR-QELKTVKKNYEALKQRQDEEKMVQSSppvsgednKWERESQETTRELLKVKDRLieve 1051
Cdd:COG4717 344 DRIEELQELLREAEELEEELQlEELEQEIAALLAEAGVEDEEELRAAL--------EQAEEYQELKEELEELEEQL---- 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1052 rNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLqvenstlnSQSTSLmnqnAQLLIQQ 1131
Cdd:COG4717 412 -EELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL--------EEDGEL----AELLQEL 478
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1378869096 1132 SSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE----RQASEY 1173
Cdd:COG4717 479 EELKAELRELAEEWAALKLALELLEEAREEYREERLppvlERASEY 524
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
625-1334 |
2.08e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.89 E-value: 2.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 625 ERAEELENELHHLEKENELL--QKKITNLKITCEKIEALEQENSELERENRKyKKTLDSFKNLTFQLESLEKENSQLDEE 702
Cdd:pfam01576 19 ERQQKAESELKELEKKHQQLceEKNALQEQLQAETELCAEAEEMRARLAARK-QELEEILHELESRLEEEEERSQQLQNE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 703 NLELRRNVESLkcasmkmaQLQLENKELESEKEQLKKglelmKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:pfam01576 98 KKKMQQHIQDL--------EEQLDEEEAARQKLQLEK-----VTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEF 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 783 ESELQDLEMENQTLQK--NLEELKISskrleQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Cdd:pfam01576 165 TSNLAEEEEKAKSLSKlkNKHEAMIS-----DLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 861 NLEKENKTLFKEIgiyKESCIRLKELEKENKELVKRatidiktLVTLREDLVSEKLKTQQMNNDLEKLTHELEkiGLNKE 940
Cdd:pfam01576 240 KKEEELQAALARL---EEETAQKNNALKKIRELEAQ-------ISELQEDLESERAARNKAEKQRRDLGEELE--ALKTE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 941 rlLHDEQSTDDRYKLLESKLE---STLKKSLEikeekiaalearlEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQ 1017
Cdd:pfam01576 308 --LEDTLDTTAAQQELRSKREqevTELKKALE-------------EETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNK 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1018 SSppVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNT 1097
Cdd:pfam01576 373 AN--LEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLN 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1098 TLQTQNAKLQVENSTLNSQStslmnQNAQLLIQQSSLENENESvikeredlkslydslikdhEKLELLHERQASEYESLI 1177
Cdd:pfam01576 451 EAEGKNIKLSKDVSSLESQL-----QDTQELLQEETRQKLNLS-------------------TRLRQLEDERNSLQEQLE 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1178 AKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLL 1257
Cdd:pfam01576 507 EEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL 586
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1258 KETE-------VLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQI 1330
Cdd:pfam01576 587 VDLDhqrqlvsNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEM 666
|
....
gi 1378869096 1331 QTLM 1334
Cdd:pfam01576 667 EDLV 670
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
881-1373 |
2.45e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.77 E-value: 2.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 881 IRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLK-TQQMNNDLEKLTHELEKIGLNKERLlhdeQSTDDRYKLLESK 959
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLReINEISSELPELREELEKLEKEVKEL----EELKEEIEELEKE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 960 LEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQ------ELKTVKKNYEALKQRQDEEKMVQSSppVSGEDNKWERES 1033
Cdd:PRK03918 247 LES-LEGSKRKLEEKIRELEERIEELKKEIEELEEkvkelkELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEEI 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1034 QETTR---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVEN 1110
Cdd:PRK03918 324 NGIEErikELEEKEERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRLTGLTPEKLEKELEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1111 stLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKS------LYDSLIKDHEKLELLherqaSEYESLIakhgtlk 1184
Cdd:PRK03918 396 --LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTEEHRKELL-----EEYTAEL------- 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1185 sahKNLEVEHKDLEDRYNQLLKQkgqLEDLEKTLKVEQEkmLLKNKnheTVAAEYKKLCGENDRLNhtynqlLKETEVLQ 1264
Cdd:PRK03918 462 ---KRIEKELKEIEEKERKLRKE---LRELEKVLKKESE--LIKLK---ELAEQLKELEEKLKKYN------LEELEKKA 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1265 TDHKNLKSLLNSSRLEQTRLEAEFSKLKEqyqqlditstkLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1344
Cdd:PRK03918 525 EEYEKLKEKLIKLKGEIKSLKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEER 593
|
490 500
....*....|....*....|....*....
gi 1378869096 1345 MESKDLFHVEQRQYIDKLNELRRQKEKLE 1373
Cdd:PRK03918 594 LKELEPFYNEYLELKDAEKELEREEKELK 622
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
990-1207 |
3.25e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.32 E-value: 3.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 990 QQLRQELKTVKKNYEALKQRQDEEKMVQSSppVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1069
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKA--LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1070 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1148 LKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQ 1207
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
611-1368 |
3.30e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 62.24 E-value: 3.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 611 RQIRKELEHYKEKGERAEELENELHHLEKENELlqkkitnlkitCEKIEALEQENSELEREnrkyKKTLDSFKNLTfQLE 690
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEPIREL-----------AERYAAARERLAELEYL----RAALRLWFAQR-RLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 691 SLEKEnsqLDEENLELRRNVEslkcasmKMAQLQLENKELESEKEQLKKglELMKASFKKTERLEvsyqgldTENQRLQK 770
Cdd:COG4913 292 LLEAE---LEELRAELARLEA-------ELERLEARLDALREELDELEA--QIRGNGGDRLEQLE-------REIERLER 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 771 ALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaEIKD 849
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 850 ttLEENNVKI-GNLEKENKTLFKEIGIYKESC------IRLKELEKENKELVKRAtidiktLVTLRED-LVSEKlktqqm 921
Cdd:COG4913 431 --LERRKSNIpARLLALRDALAEALGLDEAELpfvgelIEVRPEEERWRGAIERV------LGGFALTlLVPPE------ 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 922 nnDLEKLTHELEKIGLnKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAA-LEARLEESTNY-----NQQLRQE 995
Cdd:COG4913 497 --HYAAALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRFDYvcvdsPEELRRH 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 996 LK------TVKKNYEAlkQRQDEEKMVQSSPpVSGEDNkweresqettRELLKVKDRLIevernnATLQAEKQALKTQLK 1069
Cdd:COG4913 574 PRaitragQVKGNGTR--HEKDDRRRIRSRY-VLGFDN----------RAKLAALEAEL------AELEEELAEAEERLE 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1070 QLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqvenstlnsqstslmnqnaqllIQQssLENENESVIKEREDLK 1149
Cdd:COG4913 635 ALEAELDALQERREALQRLAEYSWDEIDVASAERE------------------------IAE--LEAELERLDASSDDLA 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1150 SLYDSLikdhEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQL--LKQKGQLEDLEKTLKVEQEKmll 1227
Cdd:COG4913 689 ALEEQL----EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAedLARLELRALLEERFAAALGD--- 761
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1228 knKNHETVAAEY-KKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSS------------RLEQTRL---EAEFSKL 1291
Cdd:COG4913 762 --AVERELRENLeERIDALRARLNRAEEELERAMRAFNREWPAETADLDADleslpeylalldRLEEDGLpeyEERFKEL 839
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1292 KEQyqqlditstklnNQCELLSQLKGNLEEENRHLLDQIQTLmlqNRTLLEQN--------MESKDLFHVEQRQYIDKLN 1363
Cdd:COG4913 840 LNE------------NSIEFVADLLSKLRRAIREIKERIDPL---NDSLKRIPfgpgrylrLEARPRPDPEVREFRQELR 904
|
....*
gi 1378869096 1364 ELRRQ 1368
Cdd:COG4913 905 AVTSG 909
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
616-1417 |
3.74e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 62.37 E-value: 3.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 616 ELEHYKEKGERAEELENEL----HHLEKENELLQKK---ITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQ 688
Cdd:TIGR00606 208 ELKYLKQYKEKACEIRDQItskeAQLESSREIVKSYeneLDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSE 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 689 LESLEKENSQLDEENL-ELRRNVES-LKCASMKMAQLQLENKELESEKEQLKKglelmkasfKKTERL-EVSYQGLDTEN 765
Cdd:TIGR00606 288 LELKMEKVFQGTDEQLnDLYHNHQRtVREKERELVDCQRELEKLNKERRLLNQ---------EKTELLvEQGRLQLQADR 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 766 QRLQKALENSNKKIQQLESELQDLEME--NQTLQKNLEELKIsskrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:TIGR00606 359 HQEHIRARDSLIQSLATRLELDGFERGpfSERQIKNFHTLVI-----ERQEDEAKTAAQLCADLQSKERLKQEQADEIRD 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 844 QAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKE-NKELVKRATIDIKTLV-TLREDLVSEKLKTQQM 921
Cdd:TIGR00606 434 EKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQElRKAERELSKAEKNSLTeTLKKEVKSLQNEKADL 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 922 NNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEE-----KIAALEARLEESTNYNQQLRQEL 996
Cdd:TIGR00606 514 DRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpNKKQLEDWLHSKSKEINQTRDRL 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 997 KTVKKNYEALKQRQDE---EKMVQSSPPVSGEDNKWER-ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1072
Cdd:TIGR00606 594 AKLNKELASLEQNKNHinnELESKEEQLSSYEDKLFDVcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLT 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1073 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLY 1152
Cdd:TIGR00606 674 DENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKL 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1153 DSLIKDHEKLELLHERQASEYESLIAKHGTLK------SAHKNLEVEHKDLEDRYNQLLkQKGQLEDLEKTLKVEQEKML 1226
Cdd:TIGR00606 754 QKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltdvTIMERFQMELKDVERKIAQQA-AKLQGSDLDRTVQQVNQEKQ 832
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1227 LKNKNHETVAAEYKklcgENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
Cdd:TIGR00606 833 EKQHELDTVVSKIE----LNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAK 908
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1307 NQCELLSQLKGNLEEENRHLLDQIQT--------LMLQNRTLLEQNMESKDLFHVEQ----RQYIDK----------LNE 1364
Cdd:TIGR00606 909 EQDSPLETFLEKDQQEKEELISSKETsnkkaqdkVNDIKEKVKNIHGYMKDIENKIQdgkdDYLKQKetelntvnaqLEE 988
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 1365 LRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSL 1417
Cdd:TIGR00606 989 CEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHL 1041
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
505-858 |
8.08e-09 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 60.47 E-value: 8.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 505 KKVEILENEIIQEKQS-LQNCQNLSKDLMKEKAQLEKTIETLRENSER--------QIKILEQENEhlnqtVSSLRQRSQ 575
Cdd:pfam05622 30 KNSLQQENKKLQERLDqLESGDDSGTPGGKKYLLLQKQLEQLQEENFRletarddyRIKCEELEKE-----VLELQHRNE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 576 --ISAEARVKDIEKENKILhesiKETSSKLSKIEfekrqirKELEHYKEKGERAEELENELHHLEKEN-ELLQ------- 645
Cdd:pfam05622 105 elTSLAEEAQALKDEMDIL----RESSDKVKKLE-------ATVETYKKKLEDLGDLRRQVKLLEERNaEYMQrtlqlee 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 646 --KKITNLKITCEKIEALEQE-NSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Cdd:pfam05622 174 elKKANALRGQLETYKRQVQElHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELRCAQLQQAE 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 723 LQLENKELESEKEQLKK-GLELMKASFKKT-ERLEVSYQGLD-----TENQR---LQKALENSNKKIQQLESEL-----Q 787
Cdd:pfam05622 254 LSQADALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRlgqegSYRERlteLQQLLEDANRRKNELETQNrlanqR 333
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 788 DLEMENQT--LQKNLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVK 858
Cdd:pfam05622 334 ILELQQQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRK 410
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1223 |
1.12e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.47 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEnktlfkeigiyKESCIRLKELEKENKELvkRATIDIKT 903
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-----------REKAERYQALLKEKREY--EGYELLKE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 904 LVTLREDLvseklktQQMNNDLEKLTHELEKIglnKERLlhdeQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLE 983
Cdd:TIGR02169 232 KEALERQK-------EAIERQLASLEEELEKL---TEEI----SELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIG 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 984 EstnynqqLRQELKTVKKNYEALKQRQDEEkmvqssppvsgednkwERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1063
Cdd:TIGR02169 298 E-------LEAEIASLERSIAEKERELEDA----------------EERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1064 LKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIK 1143
Cdd:TIGR02169 355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1144 EREDLKSLYDSLIKDHEKLEllherqaSEYESLIAKHGTLKSAHKNLEVEHKDLEDRynqLLKQKGQLEDLEKTLKVEQE 1223
Cdd:TIGR02169 435 KINELEEEKEDKALEIKKQE-------WKLEQLAADLSKYEQELYDLKEEYDRVEKE---LSKLQRELAEAEAQARASEE 504
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1201 |
1.48e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.78 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 770 KALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 848 KDT---TLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 925 LEKLTHELEKIGLNKERLLHDEQSTDDRYKLL--------------ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 990
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLiaaallallglggsLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 991 QLRQELKTVKKNYEALKQRQDEEKMVQS-SPPVSGEDNKWERESQETTRELLKVKDRLIEvERNNATLQAEKQALktqLK 1069
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEELEE-ELQLEELEQEIAAL---LA 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1070 QLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4717 378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAE 457
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 1148 LKSLYDSLIKDHEKLELLHERQ--ASEYESLIAKHGTLKSAHKNLEVEHKDLEDRY 1201
Cdd:COG4717 458 LEAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1157 |
1.96e-08 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 59.93 E-value: 1.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 796 LQKNLEELKissKRlEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKE 872
Cdd:PRK11281 41 VQAQLDALN---KQ-KLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 873 IgIYKEScirLKELEKE-NKELVKRATIDiKTLVTLREDLVSEK--------------LKTQQMNNDLEKLTHELEKIGL 937
Cdd:PRK11281 117 T-LSTLS---LRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSLQtqperaqaalyansQRLQQIRNLLKGGKVGGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 938 NKERLLHDEQS-----TDDRYKLLE--SKLESTLKKSLEIKEEKIAALEAR---LEESTNyNQQLRQELKTVKknyEAlk 1007
Cdd:PRK11281 192 SQRVLLQAEQAllnaqNDLQRKSLEgnTQLQDLLQKQRDYLTARIQRLEHQlqlLQEAIN-SKRLTLSEKTVQ---EA-- 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1008 QRQDEEKMVQSSPPVSGEdnkweresQETTRELlkvKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL-- 1085
Cdd:PRK11281 266 QSQDEAARIQANPLVAQE--------LEINLQL---SQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLkg 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1086 ----------QRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SVIKERED 1147
Cdd:PRK11281 335 slllsrilyqQQQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDERRE 414
|
410
....*....|
gi 1378869096 1148 lksLYDSLIK 1157
Cdd:PRK11281 415 ---LLDQLNK 421
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
288-788 |
3.27e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 3.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 288 LKRLQQENMNLLS-DARSARMYRDELDALREKavrVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Cdd:COG4717 48 LERLEKEADELFKpQGRKPELNLKELKELEEE---LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 367 LEgtrarsdkLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQsmdeslhlgweleqisrtselseap 446
Cdd:COG4717 125 LQ--------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAE------------------------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 447 QKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEgttSKILKIEKENQRLSKKVEILENE--IIQEKQSLQNC 524
Cdd:COG4717 172 LAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELE---EELEEAQEELEELEEELEQLENEleAAALEERLKEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 525 QNLSKDL--MKEKAQLEKTIETLRENSERQIKILEQenehLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602
Cdd:COG4717 249 RLLLLIAaaLLALLGLGGSLLSLILTIAGVLFLVLG----LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 603 LSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNL--KITCEKIEALEQeNSELERENRKYKKT 678
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLeeLEQEIAALlaEAGVEDEEELRA-ALEQAEEYQELKEE 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 679 LDSFKN-LTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKtERLE 755
Cdd:COG4717 404 LEELEEqLEELLGELEELLEALDEEELeeELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL-EELK 482
|
490 500 510
....*....|....*....|....*....|...
gi 1378869096 756 VSYQGLDTENQRLQKALENSNKKIQQLESELQD 788
Cdd:COG4717 483 AELRELAEEWAALKLALELLEEAREEYREERLP 515
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
252-1368 |
3.40e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 59.29 E-value: 3.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKrlqqENMNLLSDARSARMYRDELDALREK----AVRVDK--- 324
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIK----AQINDLEDVADKAISNDDPEEIEKKieniVTKIDKkkn 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 325 LESEVSRYKERLHDIEFYKARVEELKEDNQVLLET--KTMLEDQLEGTRARSDKLHELEK-----ENLQLKAKLHDMEME 397
Cdd:TIGR01612 1188 IYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNlgKLFLEKIDEEKKKSEHMIKAMEAyiedlDEIKEKSPEIENEMG 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 398 RDMDRKKIEELM-------EENMTLEMAQKQSM----DESLHLGWELEQISRTSELSEAPQKSL------GHEVNELTSS 460
Cdd:TIGR01612 1268 IEMDIKAEMETFnishdddKDHHIISKKHDENIsdirEKSLKIIEDFSEESDINDIKKELQKNLldaqkhNSDINLYLNE 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 461 -----RLLKLEM------ENQSLTKTVEELRSTMDSAEGTTSKILKIEKENQRL----SKKVEILENEIIQEkqSLQNCQ 525
Cdd:TIGR01612 1348 ianiyNILKLNKikkiidEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeckSKIESTLDDKDIDE--CIKKIK 1425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:TIGR01612 1426 ELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDE 1501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 606 IEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKtldsFKNL 685
Cdd:TIGR01612 1502 ADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKE 1577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKglelmkasfkkterlEVSYQGLDTEN 765
Cdd:TIGR01612 1578 KFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEK---------------KISSFSIDSQD 1642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 766 QRLQKALENSNkkiqqleselqdlemenqTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKenkrlrqqa 845
Cdd:TIGR01612 1643 TELKENGDNLN------------------SLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKK--------- 1695
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 846 eikdttleenNVKIGNLEKenktlfkeigiykescirLKELEKENKELVKRATIDIKTLVtlredlvsEKLKTQQMNNDL 925
Cdd:TIGR01612 1696 ----------NYEIGIIEK------------------IKEIAIANKEEIESIKELIEPTI--------ENLISSFNTNDL 1739
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 926 EKLTHElEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSL---EIKEEKIAAlearleestnyNQQLRQELKTVKKN 1002
Cdd:TIGR01612 1740 EGIDPN-EKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKEPItydEIKNTRINA-----------QNEFLKIIEIEKKS 1807
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1003 YEALkqrqDEEKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVER--NNATLQAEKQALKTQLKQLETQNNNLQA 1080
Cdd:TIGR01612 1808 KSYL----DDIEAKEFDRIINHFKKKLDHVNDKFTKEYSKINEGFDDISKsiENVKNSTDENLLFDILNKTKDAYAGIIG 1883
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1081 QILALQRQTVSLQEQNTTLQTQNAKLQVENstlNSQSTSLMNQNAQLLiqqSSLENENESVIK-----ERE-----DLKS 1150
Cdd:TIGR01612 1884 KKYYSYKDEAEKIFINISKLANSINIQIQN---NSGIDLFDNINIAIL---SSLDSEKEDTLKfipspEKEpeiytKIRD 1957
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1151 LYDSLIKDHEKLELLHERQASeyesliakhgTLKSAHKNLEVEHKdledrynqlLKQKGQLEDLEKTLKVEQEKMLlknk 1230
Cdd:TIGR01612 1958 SYDTLLDIFKKSQDLHKKEQD----------TLNIIFENQQLYEK---------IQASNELKDTLSDLKYKKEKIL---- 2014
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1231 nhetvaAEYKKLCGENDRLNHtynqllketevLQTDHKNLKSLLNSSRLEQTRLEAE-FSKLKEQYQ---QLDITSTKLN 1306
Cdd:TIGR01612 2015 ------NDVKLLLHKFDELNK-----------LSCDSQNYDTILELSKQDKIKEKIDnYEKEKEKFGidfDVKAMEEKFD 2077
|
1130 1140 1150 1160 1170 1180 1190
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 1307 NQCELLSQLKGNLE--EENRHLLDQIQTLMLQNRTLLEQ-----NMESKDLFH--VEQRQYIDKLNELRRQ 1368
Cdd:TIGR01612 2078 NDIKDIEKFENNYKhsEKDNHDFSEEKDNIIQSKKKLKElteafNTEIKIIEDkiIEKNDLIDKLIEMRKE 2148
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-894 |
3.50e-08 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 58.16 E-value: 3.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 508 EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 582 VKDIEKENKILHESIKETSSKLSKI---EFEKRQIRKELE-HYKEKGERAEELENELHHLEKENELLQKKITNLKitcEK 657
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELrieLRDKTAQAEALErQLAAETEQNRALEEENKALREEAQAAEKALQRAE---GE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 658 IEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESlKCASMK------MAQLQLENKELE 731
Cdd:pfam19220 162 LATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVEAHR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 732 SEKEQLKKGLELMKASFKKTERLevsyqgldtenqrlqkalensnkkIQQLESELQDLEMENQTLQKNLEELKIS----S 807
Cdd:pfam19220 241 AERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErdtlE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKEScirlkeLE 887
Cdd:pfam19220 297 RRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAA------LE 370
|
....*..
gi 1378869096 888 KENKELV 894
Cdd:pfam19220 371 QANRRLK 377
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
482-1374 |
4.57e-08 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 58.69 E-value: 4.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 482 TMDSAEGTTSKILKIEKenqRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqene 561
Cdd:PTZ00440 430 IADYALYSNLEIIEIKK---KYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE---- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 562 hLNQTVSSLRQRSQISAEaRVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKEN 641
Cdd:PTZ00440 503 -LLQIINSIKEKNNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENV 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 642 ELLQKKITNLKITCEKIEALEQENSELERENRKYKKtldsfknltfqleslEKENSQLDEENLELRRNVESLKCASMKMA 721
Cdd:PTZ00440 581 DHIKDIISLNDEIDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELS 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 722 QLQLENKELESEKEQLKKGLELMKASFKKTERLEvsyqgldtenqrlQKALENSNKKIQQLESELQDL-EMENQTLQKNL 800
Cdd:PTZ00440 646 HFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQL 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 801 EELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLFKEIGIYKES 879
Cdd:PTZ00440 713 NNIEQDiSNSLNQYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDT 788
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 880 CIRLKELEKENKELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKE--RLLHDEQSTDDRYKLLe 957
Cdd:PTZ00440 789 ILNKENKISNDINILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDEnlNLKELEKEFNENNQIV- 865
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 958 skleSTLKKSLEIKEEKIAALEaRLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSPPVSGEDNKwERESQETT 1037
Cdd:PTZ00440 866 ----DNIIKDIENMNKNINIIK-TLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEK-LNLLNNLN 939
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1038 RELLKVKDRLIEVERNNATLQAEKQaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENstlnsqs 1117
Cdd:PTZ00440 940 KEKEKIEKQLSDTKINNLKMQIEKT-LEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILN------- 1011
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1118 tslmnqnaqlliqqsslENENESVIKEREDLKSLYDSLIKdhEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDL 1197
Cdd:PTZ00440 1012 -----------------KKIDDLIKKQHDDIIELIDKLIK--EKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKN 1072
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1198 EDRYNQLLKQKGQLEDLEKTLKVEQEKML-LKNKNHETVAAeykkLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNS 1276
Cdd:PTZ00440 1073 PKIKEEIKLLEEKVEALLKKIDENKNKLIeIKNKSHEHVVN----ADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELEN 1148
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1277 SRLEQTRLEaEFSKLKEQYQQLDItstklnnqcELLSQLKGNLEEENRHLLDQIQtLMLQNRTLLEQNMESKDLFHVEQR 1356
Cdd:PTZ00440 1149 MNLEDITLN-EVNEIEIEYERILI---------DHIVEQINNEAKKSKTIMEEIE-SYKKDIDQVKKNMSKERNDHLTTF 1217
|
890
....*....|....*...
gi 1378869096 1357 QYIDKLNELRRQKEKLEE 1374
Cdd:PTZ00440 1218 EYNAYYDKATASYENIEE 1235
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-987 |
4.59e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 4.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 746 ASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeigiykescIRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-----------QYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAAA 238
|
...
gi 1378869096 985 STN 987
Cdd:COG4942 239 AAE 241
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-868 |
5.18e-08 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 58.55 E-value: 5.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmnllsdarsarmyrDELDALREKAVRvdkLESEVsrykerlhdIE 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLE---LESEI---------IE 910
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 341 FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN-----LQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Cdd:COG5022 911 LKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPelnklHEVESKLKETSEEYEDLLKKSTILVREGNKA 990
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 416 EMAQKQSMDESLHLGWELEQISRTSELSeapqKSLGHEVNELTS-SRLLKLEMENQSLTKTVEELRSTMDSAEGTTS--- 491
Cdd:COG5022 991 NSELKNFKKELAELSKQYGALQESTKQL----KELPVEVAELQSaSKIISSESTELSILKPLQKLKGLLLLENNQLQary 1066
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 492 KILKIEKENQRLSKK-------VEILENEiIQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLR--ENSERQIKILEQE 559
Cdd:COG5022 1067 KALKLRRENSLLDDKqlyqlesTENLLKT-INVKDLEVTNRNLVKPANVLqfiVAQMIKLNLLQEisKFLSQLVNTLEPV 1145
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 560 NEHLNQT---------VSSLRQRSQISAEAR-VKDIEKENKILHESIKETSSKL----SKIEFEKRQIRKELehykEKGE 625
Cdd:COG5022 1146 FQKLSVLqleldglfwEANLEALPSPPPFAAlSEKRLYQSALYDEKSKLSSSEVndlkNELIALFSKIFSGW----PRGD 1221
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 626 RAEELENELHHLEKENELLQKKI-TNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Cdd:COG5022 1222 KLKKLISEGWVPTEYSTSLKGFNnLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNAL 1301
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 705 ELRRNVESLKCAS-MKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTenqRLQKALENSNKKIQQLE 783
Cdd:COG5022 1302 RTKASSLRWKSATeVNYNSEELDDWCREFEISDVDEELEELIQAVKVLQLLKDDLNKLDE---LLDACYSLNPAEIQNLK 1378
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 784 SELQDLEMENQTLQKNLEELKISS-KRLEQLEKENK-SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTleENNVKIGN 861
Cdd:COG5022 1379 SRYDPADKENNLPKEILKKIEALLiKQELQLSLEGKdETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL--SALLTKEK 1456
|
....*..
gi 1378869096 862 LEKENKT 868
Cdd:COG5022 1457 IALLDRK 1463
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
243-673 |
5.54e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.86 E-value: 5.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 243 TESRQHLSVELADAKAKIRRLRQELE--EKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAV 320
Cdd:COG4717 94 QEELEELEEELEELEAELEELREELEklEKLLQLLPLYQELEALEAELAELPER----------LEELEERLEELRELEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 321 RVDKLESEVSRYKERLHDIEFY-----KARVEELKEDNQVLLETKTMLEDQLEGTRArsdklhelEKENLQLKAKLHDME 395
Cdd:COG4717 164 ELEELEAELAELQEELEELLEQlslatEEELQDLAEELEELQQRLAELEEELEEAQE--------ELEELEEELEQLENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 396 MERDMDRKKIEELMEENM------TLEMAQKQSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKl 465
Cdd:COG4717 236 LEAAALEERLKEARLLLLiaaallALLGLGGSLLSLILTIAgvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALE- 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 466 EMENQSLTKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEiIQEKQSLQNCQNLskdLMKEKAQLEKTIETL 545
Cdd:COG4717 315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE-LQLEELEQEIAAL---LAEAGVEDEEELRAA 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 546 RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYkEKGE 625
Cdd:COG4717 391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL-EEDG 469
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1378869096 626 RAEELENELHHLEKENELLQKKITNLKITcekIEALEQENSELERENR 673
Cdd:COG4717 470 ELAELLQELEELKAELRELAEEWAALKLA---LELLEEAREEYREERL 514
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
581-1376 |
5.74e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.52 E-value: 5.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Cdd:TIGR00606 201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQ 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 661 LEQENSELERENRK-YKKTLDSFKNLTF------------------QLESLEKENSQLDEENLELRRNV-------ESLK 714
Cdd:TIGR00606 281 MEKDNSELELKMEKvFQGTDEQLNDLYHnhqrtvrekerelvdcqrELEKLNKERRLLNQEKTELLVEQgrlqlqaDRHQ 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 715 CASMKMAQLQLENkELESEKEQLKKG----LELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDL- 789
Cdd:TIGR00606 361 EHIRARDSLIQSL-ATRLELDGFERGpfseRQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLg 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 790 ---EMENQTLQKNLEELKI----------SSKRLEQLEKENKSLEQETSQLEKDK--KQLEKENKRLRQQAEIKDTTLEE 854
Cdd:TIGR00606 440 rtiELKKEILEKKQEELKFvikelqqlegSSDRILELDQELRKAERELSKAEKNSltETLKKEVKSLQNEKADLDRKLRK 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 855 NNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKEN----KELVKRATiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:TIGR00606 520 LDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKsrhsDELTSLLG-YFPNKKQLEDWLHSKSKEINQTRDRLAKLNK 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 931 ELEKIGLNKERLLHDEQSTDDRYKLLESKL---------ESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQELKTVKK 1001
Cdd:TIGR00606 599 ELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsqdeESDLER-LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQ 677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1002 NYEALKQR--QDEEKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1079
Cdd:TIGR00606 678 SCCPVCQRvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVN 757
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1080 AQIlalQRQTVSLQEQNTTLQTQNAKLQVENSTLNS---------QSTSLMNQNAQLL--IQQSSLENENESVIKEREDL 1148
Cdd:TIGR00606 758 RDI---QRLKNDIEEQETLLGTIMPEEESAKVCLTDvtimerfqmELKDVERKIAQQAakLQGSDLDRTVQQVNQEKQEK 834
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1149 KSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLlk 1228
Cdd:TIGR00606 835 QHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS-- 912
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1229 nknheTVAAEYKKLCGENDRLNHTYNQllkETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQY-QQLDITSTKLNN 1307
Cdd:TIGR00606 913 -----PLETFLEKDQQEKEELISSKET---SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYlKQKETELNTVNA 984
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1308 QCELLSQLKGNLEEENRHLLDQIQTLMLQNR------TLLEQNMESKDLfHVEQRQYIDKLNELR-----RQKEKLEEKI 1376
Cdd:TIGR00606 985 QLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnlTLRKRENELKEV-EEELKQHLKEMGQMQvlqmkQEHQKLEENI 1063
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
743-897 |
5.75e-08 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 57.95 E-value: 5.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 743 LMKASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQ 822
Cdd:COG2433 382 LEELIEKELPEEEPEAEREKEHEERELTEEE---EEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARS 455
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 823 ET-SQLEKDKK--QLEKENKRLRQQAEIKDTTLEENNVKignLEKENKTLFKEIgiyKESCIRLKELEKENKELVKRA 897
Cdd:COG2433 456 EErREIRKDREisRLDREIERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
334-652 |
6.32e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.83 E-value: 6.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 334 ERLHDIEFYKARVEELKEDNQVL---LETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELME 410
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKareVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKR 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 411 ENMTLEMAQkqsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLK-LEMENQSLTKT----VEELRSTMDS 485
Cdd:pfam17380 361 ELERIRQEE---------IAMEISRMRELERLQMERQQKNERVRQELEAARKVKiLEEERQRKIQQqkveMEQIRAEQEE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 486 AEGTTSKILKIEKEnqrlsKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnq 565
Cdd:pfam17380 432 ARQREVRRLEEERA-----REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--- 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 566 tvsslRQRSQISAEARVKDIEKENKILHESIKETSSKlsKIEFEKRQIRKELEHYK---EKGERAEELENELHHLEKENE 642
Cdd:pfam17380 504 -----RKQAMIEEERKRKLLEKEMEERQKAIYEEERR--REAEEERRKQQEMEERRriqEQMRKATEERSRLEAMERERE 576
|
330
....*....|
gi 1378869096 643 LLQKKITNLK 652
Cdd:pfam17380 577 MMRQIVESEK 586
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
244-827 |
7.00e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 57.88 E-value: 7.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMyrdeldALREKAVRVD 323
Cdd:pfam01576 496 DERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQ------QLEEKAAAYD 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 324 KLESEVSRYKERLHDIEFYKARVEEL--------KEDNQVLLETKTML------EDQLEG------TRARS--------- 374
Cdd:pfam01576 570 KLEKTKNRLQQELDDLLVDLDHQRQLvsnlekkqKKFDQMLAEEKAISaryaeeRDRAEAearekeTRALSlaraleeal 649
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 375 DKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmAQKQSMDESLHlgwELEqisrtSELSEAPQKSLGHEV 454
Cdd:pfam01576 650 EAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALE-QQVEEMKTQLE---ELE-----DELQATEDAKLRLEV 720
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 455 NEltssrllklemenQSLTKTVEELRSTMDSAEgttskilkiEKENQRLSKKVEILENEIIQEK----QSLQNCQNLSKD 530
Cdd:pfam01576 721 NM-------------QALKAQFERDLQARDEQG---------EEKRRQLVKQVRELEAELEDERkqraQAVAAKKKLELD 778
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 531 LMKEKAQLEKTIETlRENSERQIKILEQENEHLNQTVSSLRQrSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEK 610
Cdd:pfam01576 779 LKELEAQIDAANKG-REEAVKQLKKLQAQMKDLQRELEEARA-SRDEILAQSKESEKKLKNLEAELLQLQEDLAASERAR 856
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 611 RQIRkelehyKEKGERAEELENEL---HHLEKENELLQKKITNLKitcekiEALEQENSELERENRKYKKTLDSFKNLTF 687
Cdd:pfam01576 857 RQAQ------QERDELADEIASGAsgkSALQDEKRRLEARIAQLE------EELEEEQSNTELLNDRLRKSTLQVEQLTT 924
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 688 QL-------ESLEKENSQLDEENLELRRNVESLKCA-----SMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERL- 754
Cdd:pfam01576 925 ELaaerstsQKSESARQQLERQNKELKAKLQEMEGTvkskfKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKl 1004
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 755 -EVSYQGLDTENQRLQ--KALENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQL 827
Cdd:pfam01576 1005 kEVLLQVEDERRHADQykDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQ---RELDDATESNESMNREVSTL 1077
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
575-831 |
8.02e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 57.33 E-value: 8.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 575 QISAEARVKDIE---------KENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENElhhlekENELLQ 645
Cdd:PHA02562 146 QLSAPARRKLVEdlldisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE------NIARKQ 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 646 KKITNLKITCEKIEA-LEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCasmkMAQLQ 724
Cdd:PHA02562 220 NKYDELVEEAKTIKAeIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----TQQIS 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 725 LENKELESEKEQLK---KGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQknlE 801
Cdd:PHA02562 296 EGPDRITKIKDKLKelqHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ---A 372
|
250 260 270
....*....|....*....|....*....|
gi 1378869096 802 ELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:PHA02562 373 EFVDNAEELAKLQDELDKIVKTKSELVKEK 402
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
1.12e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.06 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 559 ENEHLNQTVSSLRQRSQISAEarvKDIEKENKILHESIKETSSKLSKiEFEKRQIRKELEH------------YKEKGER 626
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSER---QQQEKFEKMEQERLRQEKEEKAR-EVERRRKLEEAEKarqaemdrqaaiYAEQERM 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 627 AEELENELHHL---EKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Cdd:pfam17380 343 AMERERELERIrqeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 704 LELRRNVESLKcasmkmaqlQLENKELESEKEQlkkglELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:pfam17380 423 EQIRAEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 784 SElqdlEMENQTLQKNLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Cdd:pfam17380 489 AE----EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 864 K--ENKTLFKEIGIYKESCIRLKELEKENKELvkRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 560 KatEERSRLEAMEREREMMRQIVESEKARAEY--EATTPITTIKPIYRPRISE 610
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-893 |
1.98e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.54 E-value: 1.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 726 ENKELESEKEQLKKGLELMKASFKKTERLEVSYQG----LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 802 ELK-----------------------------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:COG4942 101 AQKeelaellralyrlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1378869096 853 EENNVKIGNLE---KENKTLFKEI-GIYKESCIRLKELEKENKEL 893
Cdd:COG4942 181 AELEEERAALEalkAERQKLLARLeKELAELAAELAELQQEAEEL 225
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
253-782 |
3.35e-07 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 55.52 E-value: 3.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmnllsdarsaRMYRDELDALREKAVRVDKLESEVSRY 332
Cdd:pfam05557 99 LADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERL----------DLLKAKASEAEQLRQNLEKQQSSLAEA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 333 KERLHDIEF----YKARVEELKEDNQVLLETKTMlEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDmdrkKIEEL 408
Cdd:pfam05557 169 EQRIKELEFeiqsQEQDSEIVKNSKSELARIPEL-EKELERLREHNKHLNENIENKLLLKEEVEDLKRKLE----REEKY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 409 MEENMTLEMaqkqsmdeslhlgweleqisrtselseapqkslghevneltssRLLKLEMENQSLTKTVEELRSTMDSAEG 488
Cdd:pfam05557 244 REEAATLEL-------------------------------------------EKEKLEQELQSWVKLAQDTGLNLRSPED 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 489 TTSKILKIEKENQRLSKKVEILENEIIQE----KQSLQNCQNLSKDLMKEKAQLEKTiETLRENSERQIKILEQENEHLN 564
Cdd:pfam05557 281 LSRRIEQLQQREIVLKEENSSLTSSARQLekarRELEQELAQYLKKIEDLNKKLKRH-KALVRRLQRRVLLLTKERDGYR 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 565 QTVSSLrqRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKekgERAEELENELHHLEKENELL 644
Cdd:pfam05557 360 AILESY--DKELTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLA 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 645 QKKITNLKITC--EKIEALEQENSELEREnrkyKKTLDSfknltfqleSLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Cdd:pfam05557 435 DPSYSKEEVDSlrRKLETLELERQRLREQ----KNELEM---------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQ 501
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 723 LQLENKELESEKEQLKKGLELMKASFKKTERL-EVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:pfam05557 502 RKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLpETTSTMNFKEVLDLRKELESAELKNQRL 562
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-981 |
4.03e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.16 E-value: 4.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETSSKLSKIEFEKRQIRKELEHYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 626 RAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENrkYKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Cdd:COG4717 157 ELRELEEELEELEAELAELQ----------EELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 706 LRRNVESLKcasmKMAQLQLENKELESEKEQLK----------KGLELMKASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:COG4717 225 LEEELEQLE----NELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 776 NKKIQQLESELQDLEMENQTLQKNLEELKISskrleqlEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDttleen 855
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGLP-------PDLSPEELLELLDRIEELQELLREAEELEEELQLEE------ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 856 nvkignLEKENKTLFKEIGIYKE----SCIRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHE 931
Cdd:COG4717 368 ------LEQEIAALLAEAGVEDEeelrAALEQAEEYQELKEELEELEEQLEELLGELEEL-LEALDEEELEEELEELEEE 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 932 LEKIGLNKERLLHDEQSTDDRYKLLESKLE-STLKKSLEIKEEKIAALEAR 981
Cdd:COG4717 441 LEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAELRELAEE 491
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-695 |
4.72e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 55.36 E-value: 4.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 183 QEEIEPLLKNMVLHLKRLIDERDEHSETIIELSEERDGLHFPPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 263 LRQELEEKTEQLLD----CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHD 338
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 339 IEfykarveelKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENlQLKAKLHDMEMERDMDRKKIEELMEENMTLEMA 418
Cdd:TIGR00618 544 EE---------DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDN-RSKEDIPNLQNITVRLQDLTEKLSEAEDMLACE 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 419 QKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSsrLLKLEMENQSLTKTVEELRSTmdsaegttskilkieK 498
Cdd:TIGR00618 614 QHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLT--LTQERVREHALSIRVLPKELL---------------A 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 499 ENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:TIGR00618 677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 579 EARVKDIEKENK---ILHESIKETSSKLSKIEFEKRQIRKELEHYKE-KGERAEELENELHHLEKENELLQKKITNLKit 654
Cdd:TIGR00618 757 KARTEAHFNNNEevtAALQTGAELSHLAAEIQFFNRLREEDTHLLKTlEAEIGQEIPSDEDILNLQCETLVQEEEQFL-- 834
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1378869096 655 cEKIEALEQENSELERENRKYKKTLDSFKNLT---FQLESLEKE 695
Cdd:TIGR00618 835 -SRLEEKSATLGEITHQLLKYEECSKQLAQLTqeqAKIIQLSDK 877
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
410-1075 |
4.80e-07 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 55.21 E-value: 4.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 410 EENMTLEMaQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEgt 489
Cdd:pfam10174 67 EENQHLQL-TIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEME-- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 490 tskiLKIEKENQRLSKKveileNEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Cdd:pfam10174 144 ----LRIETQKQTLGAR-----DESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREE 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 570 LRQRSQISAEArvkdieKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGEraeeleneLHHLEKENELLQKKI- 648
Cdd:pfam10174 215 LHRRNQLQPDP------AKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGL--------LHTEDREEEIKQMEVy 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 649 -TNLKITCEKIEALEQENSELERENRKYKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVES---- 712
Cdd:pfam10174 281 kSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNqnsdckqhievLKESLTAKEQRAAILQTEVDALRLRLEEkesf 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 713 LKCASMKMAQLQLENKELESEKEQLKKGLELMKASF----KKTERL-------EVSYQGLDTENQRLQKALENSNKKIQQ 781
Cdd:pfam10174 361 LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKInvlqKKIENLqeqlrdkDKQLAGLKERVKSLQTDSSNTDTALTT 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 782 LESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Cdd:pfam10174 441 LEEALSEKERIIERLKEQRErEDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLK 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 861 NLEKENKTlfkeigiYKESCIRLKELEK--ENKELVKRATIDIKTLVTLREDLVS----EKLKTQQMNNDLEKLTHELEK 934
Cdd:pfam10174 521 SLEIAVEQ-------KKEECSKLENQLKkaHNAEEAVRTNPEINDRIRLLEQEVArykeESGKAQAEVERLLGILREVEN 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 935 IGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL--EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:pfam10174 594 EKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLleEARRREDNLADNSQQLQLEELMGALEKTRQELDA 673
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1013 EKMVQSSPPVS-----GEDNKWERESQETTRELLKVKDR--------------LIEVERNN--------ATLQAEKQALK 1065
Cdd:pfam10174 674 TKARLSSTQQSlaekdGHLTNLRAERRKQLEEILEMKQEallaaisekdaniaLLELSSSKkkktqeevMALKREKDRLV 753
|
730
....*....|
gi 1378869096 1066 TQLKQlETQN 1075
Cdd:pfam10174 754 HQLKQ-QTQN 762
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
5.71e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 54.07 E-value: 5.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 657 KIEALEQENSELERENRKYKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 737 LKKGLELMKASFKKTERLEV-----SYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---ALKA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
340-1012 |
7.27e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.59 E-value: 7.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 340 EFYKARVEELKEDNQVLLETKTMLEDQLEgTRARSDKLH---ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR00618 156 QFLKAKSKEKKELLMNLFPLDQYTQLALM-EFAKKKSLHgkaELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 417 MAQKQSMDeslhlgWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSltKTVEELRSTMDSAEgTTSKILKI 496
Cdd:TIGR00618 235 LQQTQQSH------AYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQ--ERINRARKAAPLAA-HIKAVTQI 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 497 EKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLmKEKAQLEKTI----ETLRENSERQIKILEQ------ENEHL--- 563
Cdd:TIGR00618 306 EQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI-EEQRRLLQTLhsqeIHIRDAHEVATSIREIscqqhtLTQHIhtl 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 564 NQTVSSLRQRSQISAEARVKDIEKENKIL-----------HESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELEN 632
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDtrtsafrdlqgQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 633 ELHHLEKENELLQKKITNLKITCEK--IEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNV 710
Cdd:TIGR00618 465 AQSLKEREQQLQTKEQIHLQETRKKavVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSE 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 711 ESLKcasmkmAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLE 790
Cdd:TIGR00618 545 EDVY------HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKkqlEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLF 870
Cdd:TIGR00618 619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQER---VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 871 KEIGIYKESCIR-----LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQMNNDlEKLTHELEKIGLNKERLLHD 945
Cdd:TIGR00618 696 KEMLAQCQTLLRelethIEEYDREFNEIENASSSLGSDL-AAREDALNQSLKELMHQAR-TVLKARTEAHFNNNEEVTAA 773
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 946 EQsTDDRYKLLESKLESTlKKSLEIKEEKIAALEARLEEST-NYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:TIGR00618 774 LQ-TGAELSHLAAEIQFF-NRLREEDTHLLKTLEAEIGQEIpSDEDILNLQCETLVQEEEQFLSRLEE 839
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
743-1330 |
8.05e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 54.34 E-value: 8.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 743 LMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKIS----SKRLEQLEKENK 818
Cdd:pfam05483 65 LKDSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFEnekvSLKLEEEIQENK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 819 SLEQETS---------------QLEKDKK-QLEKENKR-------------------LRQQAEIKDT----TLEENNVKI 859
Cdd:pfam05483 145 DLIKENNatrhlcnllketcarSAEKTKKyEYEREETRqvymdlnnniekmilafeeLRVQAENARLemhfKLKEDHEKI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 860 GNLEKENKtlfKEIGIYKE--SCIRLKELEKENK----ELVKRATIDIKTLVTLREDLVSEKLKtqQMNNDLEKLTHELE 933
Cdd:pfam05483 225 QHLEEEYK---KEINDKEKqvSLLLIQITEKENKmkdlTFLLEESRDKANQLEEKTKLQDENLK--ELIEKKDHLTKELE 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 934 KIGLNKERLLHDEqstddryKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYN--------------QQLRQELKTV 999
Cdd:pfam05483 300 DIKMSLQRSMSTQ-------KALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSfvvtefeattcsleELLRTEQQRL 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1000 KKNYEALKQRQDE-EKMVQSSPPVSGEDNKWERESQETTRELLKVKDRLIE---VERNNATLQAEKQALKTQLKQLETQN 1075
Cdd:pfam05483 373 EKNEDQLKIITMElQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEkkqFEKIAEELKGKEQELIFLLQAREKEI 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1076 NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQS----SLENENESVIKEREDLKSL 1151
Cdd:pfam05483 453 HDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDIINCKKQEERM 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1152 YDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKmllKNKN 1231
Cdd:pfam05483 533 LKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN---KNKN 609
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1232 HETVAAEYKKL----CGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDIT---STK 1304
Cdd:pfam05483 610 IEELHQENKALkkkgSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIadeAVK 689
|
650 660 670
....*....|....*....|....*....|
gi 1378869096 1305 LNNQCELLSQLK----GNLEEENRHLLDQI 1330
Cdd:pfam05483 690 LQKEIDKRCQHKiaemVALMEKHKHQYDKI 719
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
661-1334 |
8.47e-07 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 54.44 E-value: 8.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 661 LEQENSELERE----NRKYKKTLDSFKnlTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:pfam10174 8 LQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDELRA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 737 LKKGLELMKASFKKTERlevsyqglDTENQRLQKALENSNkkIQQLESELQDLEMENQTLQKNLE--ELKISSKRlEQLE 814
Cdd:pfam10174 86 QRDLNQLLQQDFTTSPV--------DGEDKFSTPELTEEN--FRRLQSEHERQAKELFLLRKTLEemELRIETQK-QTLG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 815 KENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeigiyKESCIRLKELEKENKE 892
Cdd:pfam10174 155 ARDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPDPAK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 893 lvkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD---------RYKLLESKLEsT 963
Cdd:pfam10174 228 --------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevyksHSKFMKNKID-Q 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 964 LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDeekMVQSsppvsgEDNKWERESQETTRELLKV 1043
Cdd:pfam10174 294 LKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAA---ILQT------EVDALRLRLEEKESFLNKK 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1044 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1123
Cdd:pfam10174 365 TKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1124 NA------QLLIQQSSLEN-----ENESVIKEREDLKSLYDSLIKDHEKLEL----LHERQASEYESLIAKHGTLKSAHK 1188
Cdd:pfam10174 445 LSekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKSLEI 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1189 NLEVEHKDLEDRYNQLLKQKgQLEDLEKTlkveQEKMLLKNKNHETVAAEYK----KLCGENDRLnhtyNQLLKETEVLQ 1264
Cdd:pfam10174 525 AVEQKKEECSKLENQLKKAH-NAEEAVRT----NPEINDRIRLLEQEVARYKeesgKAQAEVERL----LGILREVENEK 595
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1265 TDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDitstKLNNQCELLSQLKGNLEEENRHLLDQIQTLM 1334
Cdd:pfam10174 596 NDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEM----KKKGAQLLEEARRREDNLADNSQQLQLEELM 661
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
957-1298 |
9.11e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 9.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 957 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQElKTVKKNYEALKQRqdeekmvqssppvsgednKWERESQET 1036
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKE------------------KREYEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1037 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1113
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1114 -----NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHK 1188
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1189 NLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMllkNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHK 1268
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADL---NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350
....*....|....*....|....*....|
gi 1378869096 1269 NLKSLLNSSRLEQTRLEAEFSKLKEQYQQL 1298
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
577-844 |
1.00e-06 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 53.70 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 577 SAEARVKDIEKENKILHESIKE--TSSKLSKIEFEK-----RQIRKELEHYKEK-GERAEELENELHHLEKENELLQKKI 648
Cdd:pfam06160 90 EIEELLDDIEEDIKQILEELDEllESEEKNREEVEElkdkyRELRKTLLANRFSyGPAIDELEKQLAEIEEEFSQFEELT 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 649 TN---------LKITCEKIEALEQENSELERENRKYKKTL-DSFKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCA 716
Cdd:pfam06160 170 ESgdylearevLEKLEEETDALEELMEDIPPLYEELKTELpDQLEELKEGYREMEEEGYALEHLNVDKEIQQleEQLEEN 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 717 SMKMAQLQLE-----NKELESEKEQLKKGLELMKASF----KKTERLEVSYQGLDTENQRLQKALENSNK---------- 777
Cdd:pfam06160 250 LALLENLELDeaeeaLEEIEERIDQLYDLLEKEVDAKkyveKNLPEIEDYLEHAEEQNKELKEELERVQQsytlnenele 329
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 778 KIQQLESELQDLEMENQTLQKNLEE-----------LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam06160 330 RVRGLEKQLEELEKRYDEIVERLEEkevayselqeeLEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLE 407
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
825-1212 |
1.30e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.62 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 825 SQLEKDKKQLEKENKRLRqqaEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRATiDIKTL 904
Cdd:COG4717 49 ERLEKEADELFKPQGRKP---ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIgLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Cdd:COG4717 125 LQLLPLYQELEALEAELAELPERLEELEERL-EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 985 STNYNQQLRQELKTVKKNYEALKQRQDEekmVQSSPPVSGEDNKWERESQ------------------------------ 1034
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQ---LENELEAAALEERLKEARLllliaaallallglggsllsliltiagvlf 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1035 -----------ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1103
Cdd:COG4717 281 lvlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1104 AKLQVEnstlnsqstSLMNQNAQLLIQQSSlenENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHG-- 1181
Cdd:COG4717 361 EELQLE---------ELEQEIAALLAEAGV---EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDee 428
|
410 420 430
....*....|....*....|....*....|.
gi 1378869096 1182 TLKSAHKNLEVEHKDLEDRYNQLLKQKGQLE 1212
Cdd:COG4717 429 ELEEELEELEEELEELEEELEELREELAELE 459
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-622 |
1.66e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 53.37 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 321 RVDKLESEVSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 478 ELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKA------------QLEKTIETL 545
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVenlqdlldratnQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 546 RENSERQIKI------LEQEN---------EHLNQTVSSLRQRSQISAEarvkDIEKENKILHESIKETSSKLSKIEFEK 610
Cdd:PLN02939 324 DQNQDLRDKVdkleasLKEANvskfssykvELLQQKLKLLEERLQASDH----EIHSYIQLYQESIKEFQDTLSKLKEES 399
|
410
....*....|..
gi 1378869096 611 RqiRKELEHYKE 622
Cdd:PLN02939 400 K--KRSLEHPAD 409
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
419-858 |
1.66e-06 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 53.04 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 419 QKQSMDESLHLGWELEQISRTSELSEAPQKSLgheVNELTSSRLLKLEMENQSLT--KTVEELRSTMDSAEGTTSKILKI 496
Cdd:COG5185 172 LNQNLKKLEIFGLTLGLLKGISELKKAEPSGT---VNSIKESETGNLGSESTLLEkaKEIINIEEALKGFQDPESELEDL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 497 EKENQRLSKKVEIlENEIIQEKqsLQNCQNLSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVsslRQR 573
Cdd:COG5185 249 AQTSDKLEKLVEQ-NTDLRLEK--LGENAESSKRLNENANNLIKQFENTKEkiaEYTKSIDIKKATESLEEQLA---AAE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 574 SQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEK-ENELLQKKITNLK 652
Cdd:COG5185 323 AEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSSEELDSFKDTIEStKESLDEIPQNQRG 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 653 ITCEKIEALEQENSELERENrkykktldsfKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELES 732
Cdd:COG5185 403 YAQEILATLEDTLKAADRQI----------EELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEI 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 733 EKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKnleelkisskrlEQ 812
Cdd:COG5185 473 NRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHI------------LA 540
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1378869096 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVK 858
Cdd:COG5185 541 LENLIPASELIQASNAKTDGQAANLRTAVIDELTQYLSTIESQQAR 586
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-701 |
1.85e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.86 E-value: 1.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 577 SAEARVKDIEKE-NKILHESIKETSSKLSKIEFEKRQ--IRKELEHYKEKGERAEELEnelhhlEKENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEeiHKLRNEFEKELRERRNELQ------KLEKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1378869096 654 tcEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKEnsQLDE 701
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE--QLQE 143
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
371-686 |
1.95e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.20 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 371 RARSDKLHELEKENLQLKAKLHDMEMERdmdRKKIEELmeenmtlEMAQKQSMDESLHLGWELEQIS--RTSELSEAPQK 448
Cdd:pfam17380 287 RQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEA-------EKARQAEMDRQAAIYAEQERMAmeRERELERIRQE 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 449 SLGHEvNELTSSRLLKLEMENqslTKTVEELRstmdsaegttskiLKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLS 528
Cdd:pfam17380 357 ERKRE-LERIRQEEIAMEISR---MRELERLQ-------------MERQQKNERVRQELEAARKVKILEEERQRKIQQQK 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 529 KDLMKEKAQLEKT----IETLRENSERQIKILEQENEHLNQTVSSLRQRSqisAEARVKDIEKEN-------------KI 591
Cdd:pfam17380 420 VEMEQIRAEQEEArqreVRRLEEERAREMERVRLEEQERQQQVERLRQQE---EERKRKKLELEKekrdrkraeeqrrKI 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 592 LHESIKETSSKLSKIEFEKRQIRKELEH-----YKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENS 666
Cdd:pfam17380 497 LEKELEERKQAMIEEERKRKLLEKEMEErqkaiYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERERE 576
|
330 340
....*....|....*....|..
gi 1378869096 667 ELER--ENRKYKKTLDSFKNLT 686
Cdd:pfam17380 577 MMRQivESEKARAEYEATTPIT 598
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
764-998 |
2.05e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 53.01 E-value: 2.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 764 ENQRLQKALENS---NKKIQQLESELQDLEMENQTLQ----KNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:PRK05771 41 SNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKELE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 836 KENKRLRQqaeikdttLEENNVKIGNLeKENKTLFKEIGIYKESCIRLKELEKENKELVKRATIDIKT---LVTLREDL- 911
Cdd:PRK05771 121 QEIERLEP--------WGNFDLDLSLL-LGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvVVVLKELSd 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 912 -VSEKLKtqqmNNDLEKLthELEKIGLNKERLlhdeQSTDDRYKLLESKLEST---LKKSLEIKEEKIAALEARLEESTN 987
Cdd:PRK05771 192 eVEEELK----KLGFERL--ELEEEGTPSELI----REIKEELEEIEKERESLleeLKELAKKYLEELLALYEYLEIELE 261
|
250
....*....|.
gi 1378869096 988 YNQQLRQELKT 998
Cdd:PRK05771 262 RAEALSKFLKT 272
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
719-865 |
2.87e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 50.69 E-value: 2.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 719 KMAQLQLENKELESEKEQLKKGLELMKASFKKTE----RLEVSYQGLDTENQRLQKALEN--SNKKIQQLESELQDLEME 792
Cdd:COG1579 25 RLKELPAELAELEDELAALEARLEAAKTELEDLEkeikRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRR 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 793 NQTLQKNLEELkisskrLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:COG1579 105 ISDLEDEILEL------MERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
775-1088 |
2.93e-06 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 51.49 E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 775 SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEqleKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQ---KDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 855 nnvkignLEKENKTLfKEigiykESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELE 933
Cdd:pfam09728 79 -------LQKQNKKL-KE-----ESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELrEKLKSLIE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 934 KIGLNKERLLHDEQSTDDRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ- 1008
Cdd:pfam09728 146 QYELRELHFEKLLKTKELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDt 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1009 -----------RQDEEKMVQSSPPVSGEDNKWERESQETTRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNN 1077
Cdd:pfam09728 226 lnksnevfttfKKEMEKMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEK 291
|
330
....*....|.
gi 1378869096 1078 LQAQILALQRQ 1088
Cdd:pfam09728 292 LENLCRALQAE 302
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1343 |
2.99e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.53 E-value: 2.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGL 761
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 762 DTENQRLQ-KALENSNKKIQQ--LESELQDLEMENQtLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQ----- 833
Cdd:pfam12128 316 AVAKDRSElEALEDQHGAFLDadIETAAADQEQLPS-WQSELENL---EERLKALTGKHQDVTAKYNRRRSKIKEqnnrd 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-NKTLFKEIGIYKESCIRLKELEKENKELVKRATIdiktlvtlredlv 912
Cdd:pfam12128 392 IAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA------------- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 913 SEKLKTQQMNND--LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 990
Cdd:pfam12128 459 TPELLLQLENFDerIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLH 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 991 QLRQELKTVKKNY-----EALKQRQDEEKMVQSSPPVSG-------------EDNKWERESQETTRELLKVKDrliever 1052
Cdd:pfam12128 539 FLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGGElnlygvkldlkriDVPEWAASEEELRERLDKAEE------- 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1053 nnaTLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQlliQQS 1132
Cdd:pfam12128 612 ---ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANE---RLN 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1133 SLENENESVIKEREDLKSLYDSLIKDH--EKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQ 1210
Cdd:pfam12128 686 SLEAQLKQLDKKHQAWLEEQKEQKREArtEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGV 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1211 leDLEKTLKVEQEKMLLKNKnHETVAAEYKKLCGENDRLNHTYNQ-------LLKETEVLQTDHK-NLKSLLNSSRLEQT 1282
Cdd:pfam12128 766 --DPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQETWLQrrprlatQLSNIERAISELQqQLARLIADTKLRRA 842
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 1283 RLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK-----GNLEEENRHLLDQIQTLMLQNRTLLEQ 1343
Cdd:pfam12128 843 KLEMERKASEKQQVRLSENLRGLRCEMSKLATLKedansEQAQGSIGERLAQLEDLKLKRDYLSES 908
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
685-1072 |
3.84e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 51.82 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 685 LTFQLESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLEN--KELESEKEQLKKGLelmKASFKKTERLEVSYQG-- 760
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEK-ERYKRDREQWERqrRELESRVAELKEEL---RQSREKHEELEEKYKEls 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 761 -----LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLE 835
Cdd:pfam07888 108 asseeLSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTE 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 836 KENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEK 915
Cdd:pfam07888 185 EELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMA 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 916 LKTQQMNNDLEKLTHELEKIGLnkerllhdeQSTDDRYKLLE-----SKLESTLKKSLEIKEEKIAAL-------EARLE 983
Cdd:pfam07888 265 AQRDRTQAELHQARLQAAQLTL---------QLADASLALREgrarwAQERETLQQSAEADKDRIEKLsaelqrlEERLQ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 984 ESTNYNQQLRQELKtvkknyealkqRQDEEKMVQSSppvsgednkweresqETTRELLKVKDRLIEVERNNATLQAEKQA 1063
Cdd:pfam07888 336 EERMEREKLEVELG-----------REKDCNRVQLS---------------ESRRELQELKASLRVAQKEKEQLQAEKQE 389
|
....*....
gi 1378869096 1064 LKTQLKQLE 1072
Cdd:pfam07888 390 LLEYIRQLE 398
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1015-1210 |
3.96e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 51.37 E-value: 3.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1015 MVQSSPPVSGED--NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsL 1092
Cdd:COG3883 5 ALAAPTPAFADPqiQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE---I 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1093 QEQNTTLQTQNAKLQVENST-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESVIKEREDLKS 1150
Cdd:COG3883 82 EERREELGERARALYRSGGSvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1151 LYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQ 1210
Cdd:COG3883 162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
597-714 |
4.10e-06 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 51.78 E-value: 4.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 597 KETSSKLSKIEFEKRQIRKELEhykEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYK 676
Cdd:COG2433 388 KELPEEEPEAEREKEHEERELT---EEEEEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARSEERREI 461
|
90 100 110
....*....|....*....|....*....|....*...
gi 1378869096 677 KTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Cdd:COG2433 462 RKDREISRLDREIERLERELEEERERIEELKRKLERLK 499
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
663-1030 |
4.34e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 52.21 E-value: 4.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 663 QENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLelrRNVESLKCASMK------MAQLQLENKELESEKEQ 736
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSL---RTVMELPQKSTSsdddhnRASMQRDEAIAAIDNEQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 737 LKKglelmkasfKKTERLEVSYQGLDtenqrLQKALENSNKKIQQLESE----LQDLE---MENQTLQKnleELKISSKR 809
Cdd:PLN02939 116 QTN---------SKDGEQLSDFQLED-----LVGMIQNAEKNILLLNQArlqaLEDLEkilTEKEALQG---KINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKE---- 885
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAEteer 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 886 ---LEKEN-------KELVKR---ATIDIKTLVTLREDLVSEKLKTQQMNndLEKLTHELEKIGLnkerLLHDEQSTDDR 952
Cdd:PLN02939 259 vfkLEKERslldaslRELESKfivAQEDVSKLSPLQYDCWWEKVENLQDL--LDRATNQVEKAAL----VLDQNQDLRDK 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 953 YKLLESKLE--STLKKS---LEIKEEKIAALEARLE---ESTNYNQQLRQELktVKKNYEALKQRQDEEKMVQSSPPVsg 1024
Cdd:PLN02939 333 VDKLEASLKeaNVSKFSsykVELLQQKLKLLEERLQasdHEIHSYIQLYQES--IKEFQDTLSKLKEESKKRSLEHPA-- 408
|
....*.
gi 1378869096 1025 EDNKWE 1030
Cdd:PLN02939 409 DDMPSE 414
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
491-648 |
4.93e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 4.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 491 SKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENserqikiLEQENEHLNQtVSSL 570
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-------IKKYEEQLGN-VRNN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 571 RQRSQI-----SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEK-GERAEELENELHHLEKENELL 644
Cdd:COG1579 89 KEYEALqkeieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAElDEELAELEAELEELEAEREEL 168
|
....
gi 1378869096 645 QKKI 648
Cdd:COG1579 169 AAKI 172
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-684 |
4.96e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 4.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 332 YKERLHDIEF---------------YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHElEKENLQLK-----AKL 391
Cdd:COG4913 364 LEALLAALGLplpasaeefaalraeAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA-EIASLERRksnipARL 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 392 HDM--EMERDMDRKKIE-----ELME---ENMTLEMA-------QKQSM-------------DESLHLGWELeqisRTSE 441
Cdd:COG4913 443 LALrdALAEALGLDEAElpfvgELIEvrpEEERWRGAiervlggFALTLlvppehyaaalrwVNRLHLRGRL----VYER 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 442 LSEAPQKSLGHEVNEltSSRLLKLEME--------NQSLTK--------TVEELRSTMDS--AEGTTSKILKI-EKENQR 502
Cdd:COG4913 519 VRTGLPDPERPRLDP--DSLAGKLDFKphpfrawlEAELGRrfdyvcvdSPEELRRHPRAitRAGQVKGNGTRhEKDDRR 596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 503 LS-----------KKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEK---TIETLRENSERQIKI---------LEQE 559
Cdd:COG4913 597 RIrsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEIDVasaereiaeLEAE 676
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 560 NEHLNQTVSSLRQrsqisAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEK 639
Cdd:COG4913 677 LERLDASSDDLAA-----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1378869096 640 ENELLQKKITNLKITCEKI--EALEQENSELERENRKYKKTLDSFKN 684
Cdd:COG4913 752 EERFAAALGDAVERELRENleERIDALRARLNRAEEELERAMRAFNR 798
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-850 |
5.44e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 51.76 E-value: 5.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 326 ESEvsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRKKI 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 406 EELMEENMTLEMAQKQSMDESLHLGweLEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN--QSLTKTVEELRSTM 483
Cdd:pfam12128 407 DRQLAVAEDDLQALESELREQLEAG--KLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENfdERIERAREEQEAAN 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 484 DSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQN------------LSKDLMKEKAQLEKTIET------- 544
Cdd:pfam12128 485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtllhfLRKEAPDWEQSIGKVISPellhrtd 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 545 ----LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSkiefekrQIRKELEHY 620
Cdd:pfam12128 565 ldpeVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLV-------QANGELEKA 637
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 621 KEKGERA----EELENELHHLEKENELLQKKITnlKITCEKIEALEQENSELERENRKYKKTLDSFknltfqLESLEKEN 696
Cdd:pfam12128 638 SREETFArtalKNARLDLRRLFDEKQSEKDKKN--KALAERKDSANERLNSLEAQLKQLDKKHQAW------LEEQKEQK 709
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 697 SQLDEENLELRRNVESLKCASM----------------KMAQLQLENK--------------ELESEKEQLKKGLELMKA 746
Cdd:pfam12128 710 REARTEKQAYWQVVEGALDAQLallkaaiaarrsgakaELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAV 789
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 747 SFKKTERLEVSYQG-LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQET 824
Cdd:pfam12128 790 RRQEVLRYFDWYQEtWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEmERKASEKQQVRLSENLRGLRCEM 869
|
650 660 670
....*....|....*....|....*....|..
gi 1378869096 825 SQL-----EKDKKQLEKE-NKRLRQQAEIKDT 850
Cdd:pfam12128 870 SKLatlkeDANSEQAQGSiGERLAQLEDLKLK 901
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
495-1316 |
5.81e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 51.98 E-value: 5.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 495 KIEKEnqrLSKKVEILENEIIQEKQSlqNCQNLSKdlMKEKAQLEKTIETLRENS----------ERQIKILEQENEHLN 564
Cdd:TIGR01612 1059 EIEKE---IGKNIELLNKEILEEAEI--NITNFNE--IKEKLKHYNFDDFGKEENikyadeinkiKDDIKNLDQKIDHHI 1131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKlsKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELL 644
Cdd:TIGR01612 1132 KALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPE--EIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSL 1209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 645 QK-KITNL-------KITCEKIEALEQENSELERENRKYKKTLDSFKNltfqlESLEKENSQLDEENLELRRNVESLKCA 716
Cdd:TIGR01612 1210 EEvKGINLsygknlgKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKE-----KSPEIENEMGIEMDIKAEMETFNISHD 1284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 717 SMKMAQLQLENKElESEKEQLKKGLELMKASFKKTErlevsyqgLDTENQRLQKALENS---NKKIQQLESELQDLE--M 791
Cdd:TIGR01612 1285 DDKDHHIISKKHD-ENISDIREKSLKIIEDFSEESD--------INDIKKELQKNLLDAqkhNSDINLYLNEIANIYniL 1355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 792 ENQTLQKNLEELKISSKrleQLEKENKSLEQETSQLEKDKKQLeKENKRLRQQAEIKDTTLEENNVK------------I 859
Cdd:TIGR01612 1356 KLNKIKKIIDEVKEYTK---EIEENNKNIKDELDKSEKLIKKI-KDDINLEECKSKIESTLDDKDIDecikkikelknhI 1431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 860 GNLEKENKTLFKEIGIYKESCIrlkeLEKENKELVKRATIDIKtlvtlredlvseKLKTQQMNNDLEKLTHELeKIGLNK 939
Cdd:TIGR01612 1432 LSEESNIDTYFKNADENNENVL----LLFKNIEMADNKSQHIL------------KIKKDNATNDHDFNINEL-KEHIDK 1494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 940 ERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEAR--LEESTNYNQQLRQELKTVKKNY--------EALKQR 1009
Cdd:TIGR01612 1495 SKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKnkFAKTKKDSEIIIKEIKDAHKKFileaekseQKIKEI 1574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1010 QDEEKMVQSSPPVSGEDNK-----------WERESQETTRELLKVKDRLIE---VERNNATLQAEKQalKTQLKQLETQN 1075
Cdd:TIGR01612 1575 KKEKFRIEDDAAKNDKSNKaaidiqlslenFENKFLKISDIKKKINDCLKEtesIEKKISSFSIDSQ--DTELKENGDNL 1652
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1076 NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQstslmNQNAQLLIqqssLENENESVIKEREDLKSLYDSL 1155
Cdd:TIGR01612 1653 NSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQH-----KKNYEIGI----IEKIKEIAIANKEEIESIKELI 1723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1156 IKDHEKleLLHERQASEYESLiakhgtlkSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTlkVEQEKMLLKNKNHETV 1235
Cdd:TIGR01612 1724 EPTIEN--LISSFNTNDLEGI--------DPNEKLEEYNTEIGDIYEEFIELYNIIAGCLET--VSKEPITYDEIKNTRI 1791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1236 AAEYKKLcgENDRLNHTYNQLLKETEVLQTDH--KNLKSLLNSSRLEQTRleaEFSKLKEQYQQLD------ITSTKLNN 1307
Cdd:TIGR01612 1792 NAQNEFL--KIIEIEKKSKSYLDDIEAKEFDRiiNHFKKKLDHVNDKFTK---EYSKINEGFDDISksienvKNSTDENL 1866
|
....*....
gi 1378869096 1308 QCELLSQLK 1316
Cdd:TIGR01612 1867 LFDILNKTK 1875
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-714 |
6.02e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 6.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 580 ARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEK------------GERAEELENELHHLEKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1378869096 648 ITNLKITCEKIE-ALEQENSELERENRKYKKTLDSFKNLTFQLE----SLEKENSQLDEENLELRRNVESLK 714
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLE 432
|
|
| BicD |
pfam09730 |
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled ... |
626-1099 |
6.65e-06 |
|
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled domains and are involved in dynein-mediated minus end-directed transport from the Golgi apparatus to the endoplasmic reticulum (ER). For full functioning they bind with GSK-3beta pfam05350 to maintain the anchoring of microtubules to the centromere. It appears that amino-acid residues 437-617 of BicD and the kinase activity of GSK-3 are necessary for the formation of a complex between BicD and GSK-3beta in intact cells.
Pssm-ID: 462863 [Multi-domain] Cd Length: 717 Bit Score: 51.40 E-value: 6.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 626 RAEELENELHHL-------EKENELLQKKITNLKITCEKIEAleqENSELERENRKYKktldsfknltFQLESLEKENSQ 698
Cdd:pfam09730 35 RILELQNELKQAravlsntQAENERLASLSQELKEECECVEL---QRGRMRDEIKEYK----------VREARLLQDYSE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 699 LDEENLELRRNVESLKcasmkmaQLQLENKELESEKEQLKKGLELMKASFKKTERL-EVSYQGLDTENQRLQKALENSNK 777
Cdd:pfam09730 102 LEEENISLQKQVSVLK-------QNQVEFEGLKHEITRKEEETELLNSQLEEAIRLrEIAERQLDEALETLKTEREQKNS 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 778 KIQQLESELQ-DLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSqlEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam09730 175 LRKELSHYMTlNDFDYVSHLSISLDGLKFSEDEGAGTEPNNDGEAMDGG--ENGGGGLKNSGLDNRTSTPRKSEVFPPAP 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 857 VKIGNLEKENKtlFKEIGIYKEsciRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLthelEKIG 936
Cdd:pfam09730 253 SLVSDLLSELN--ISEIQKLKQ---QLIQVEREKVSLLSTLQESQKQLEQAKGALSEQQEKVNRLTENLEAM----RGLQ 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 937 LNKERllhdeQSTDDRYKLLESKlESTLKKSLEIKEEKIaaLEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKmv 1016
Cdd:pfam09730 324 ASKER-----QDALDSEKDRDSH-EDGDYYEVDINGPEI--LECKYRVAVEEAGELREELKALKARYNTLEERYKEEK-- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1017 qssppvsgedNKWERESQETTrellkvkDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1096
Cdd:pfam09730 394 ----------TRWEAEAQDLA-------EKIRQLEKASHQDQERIAHLEKELGKTRKVAGESEGSLSVAQDELVTFSEEL 456
|
...
gi 1378869096 1097 TTL 1099
Cdd:pfam09730 457 ANL 459
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
733-1367 |
6.77e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 6.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 733 EKEQLKKGLELMKASFkktERLEVSYQGLDTENQRLQ--KALENSNKKIQQLESELQDLE--MENQTLQKNLEELKISSK 808
Cdd:COG4913 219 EEPDTFEAADALVEHF---DDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEylRAALRLWFAQRRLELLEA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-AEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELE 887
Cdd:COG4913 296 ELEELRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPL 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 888 KENKELVKRATIDIKTLVT--------LREDLVSEKLKTQQMNNDLEKLTHELEkiGLNKERLLHDEQSTDDRykllesk 959
Cdd:COG4913 376 PASAEEFAALRAEAAALLEaleeeleaLEEALAEAEAALRDLRRELRELEAEIA--SLERRKSNIPARLLALR------- 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 960 leSTLKKSLEIKEE--KIAA--LEARLEE----------------------------STNYNQ-QLRQELktvkkNYEAL 1006
Cdd:COG4913 447 --DALAEALGLDEAelPFVGelIEVRPEEerwrgaiervlggfaltllvppehyaaaLRWVNRlHLRGRL-----VYERV 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1007 KQRQDEEKMVQSSP-----PVSGEDNKWeresQETTRELLKVKDRLIEVErNNATLQAEKQALkT---QLKQLET----- 1073
Cdd:COG4913 520 RTGLPDPERPRLDPdslagKLDFKPHPF----RAWLEAELGRRFDYVCVD-SPEELRRHPRAI-TragQVKGNGTrhekd 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1074 ------------QNNnlQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaQLLIQQSSLENENESV 1141
Cdd:COG4913 594 drrrirsryvlgFDN--RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSWDEIDVASA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1142 IKEREDLKSLYDSLIKDHEKLELLhERQASEyesliakhgtlksahknLEVEHKDLEDRYNQLLKQKGQLEDlektlKVE 1221
Cdd:COG4913 667 EREIAELEAELERLDASSDDLAAL-EEQLEE-----------------LEAELEELEEELDELKGEIGRLEK-----ELE 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1222 QEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKET------EVLQTDHKNLKSLLNSSRleqTRLEAEFSKLKEQY 1295
Cdd:COG4913 724 QAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAverelrENLEERIDALRARLNRAE---EELERAMRAFNREW 800
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 1296 ----QQLDITSTKLNNQCELLSQLKGN-LEEENRHLLDQIQTLMLQNRTLLEQNMESkDLFHVEQRqyIDKLNE-LRR 1367
Cdd:COG4913 801 paetADLDADLESLPEYLALLDRLEEDgLPEYEERFKELLNENSIEFVADLLSKLRR-AIREIKER--IDPLNDsLKR 875
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
550-903 |
7.25e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 51.59 E-value: 7.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 550 ERQIKILEQENEHLNQTVSSLRQrsQISAEARVKDIEKEN--KILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERA 627
Cdd:PTZ00108 998 EYLLGKLERELARLSNKVRFIKH--VINGELVITNAKKKDlvKELKKLGYVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 628 EELENELHHLEKENELLQKKITNLkiTCEKIEALEQENSELERENRKYKKTldSFKNL-TFQLESLEKENSQLDEENLEL 706
Cdd:PTZ00108 1076 EDDEEELGAAVSYDYLLSMPIWSL--TKEKVEKLNAELEKKEKELEKLKNT--TPKDMwLEDLDKFEEALEEQEEVEEKE 1151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 707 RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESEL 786
Cdd:PTZ00108 1152 IAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQ 1231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 787 QDLEMENQTLQKNLEELKISSKRleqlEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Cdd:PTZ00108 1232 KTKPKKSSVKRLKSKKNNSSKSS----EDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTK 1307
|
330 340 350
....*....|....*....|....*....|....*..
gi 1378869096 867 KTLFKEigiykescIRLKELEKENKELVKRATIDIKT 903
Cdd:PTZ00108 1308 KKVKKR--------LEGSLAALKKKKKSEKKTARKKK 1336
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
978-1212 |
7.37e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 51.17 E-value: 7.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 978 LEARLEESTNYNQQLRQELKTVKKNYE----ALKQRQDEEKMVQSSppvsgednkwERESQETtrellkvkDRLIEVERN 1053
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEeaeaALEEFRQKNGLVDLS----------EEAKLLL--------QQLSELESQ 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1054 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSS 1133
Cdd:COG3206 228 LAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ 306
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1378869096 1134 LENENESVIkerEDLKSLYDSLIKDHEKLEllheRQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLE 1212
Cdd:COG3206 307 LQQEAQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
592-961 |
8.60e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 50.66 E-value: 8.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 592 LHESIKETSSKLSKIEFEKRQIRKELEHYKEKgerAEELENELHHLEKENELLQkkiTNLKITCEKIEALEQENSELERE 671
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRD---REQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 672 NrkykktldsfknltfqlESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENK-ELESEKEQLKKGLELMKASFKK 750
Cdd:pfam07888 110 S-----------------EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELERMKERAKKAGAQRKEEEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 751 TERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam07888 173 RKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 831 KKQLEKE-----NKRLRQQAEIKDTTLEENNVKI-------------GNLEKENKTLFKEIGIYKESCIRL-KELEKENK 891
Cdd:pfam07888 253 VEGLGEElssmaAQRDRTQAELHQARLQAAQLTLqladaslalregrARWAQERETLQQSAEADKDRIEKLsAELQRLEE 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE 961
Cdd:pfam07888 333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
573-861 |
9.57e-06 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 51.07 E-value: 9.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 573 RSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKrqirkelehykekgERAEELENELHHLEKENELLQKKITNLK 652
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQK--------------EETEQLKQQLAQAPAKLRQAQAELEALK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 653 ITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLekeNSQLDEENLELRRNVESLKCASMKMAQLqlenkeles 732
Cdd:PRK11281 108 DDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEY---NSQLVSLQTQPERAQAALYANSQRLQQI--------- 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 733 ekEQLKKGLELMKASFKKTER--LEVSYQGLDTENQRLQKALENSNK--------------KIQQLESELQDLemenQTL 796
Cdd:PRK11281 176 --RNLLKGGKVGGKALRPSQRvlLQAEQALLNAQNDLQRKSLEGNTQlqdllqkqrdyltaRIQRLEHQLQLL----QEA 249
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 797 qknleelkISSKRLEQLEKENKSLE--QETSQLEKD---KKQLEKeNKRLRQ---QAEIKDTTLEENNVKIGN 861
Cdd:PRK11281 250 --------INSKRLTLSEKTVQEAQsqDEAARIQANplvAQELEI-NLQLSQrllKATEKLNTLTQQNLRVKN 313
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1129-1376 |
9.61e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 9.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1129 IQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEllheRQASEYESLIAkhgTLKSAHKNLEVEHKDLEDRYNQLlkqK 1208
Cdd:TIGR02168 225 LELALLVLRLEELREELEELQEELKEAEEELEELT----AELQELEEKLE---ELRLEVSELEEEIEELQKELYAL---A 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1209 GQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQ------- 1281
Cdd:TIGR02168 295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELeelesrl 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1282 -------TRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQ--NRTLLEQNMESKDLFH 1352
Cdd:TIGR02168 375 eeleeqlETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQE 454
|
250 260
....*....|....*....|....
gi 1378869096 1353 vEQRQYIDKLNELRRQKEKLEEKI 1376
Cdd:TIGR02168 455 -ELERLEEALEELREELEEAEQAL 477
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
9.68e-06 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 48.47 E-value: 9.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 716 ASMKMAQLQLENKELESEKEQLKKglelmkasfkKTERLEVSYQGLDTENQRLQKALENSNK---KIQQLESELQDLEME 792
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQE----------QLAELRQENQELKQQLSTLEAELEELQKeleRIKQISANAIELDEE 133
|
90 100 110
....*....|....*....|....*....|....
gi 1378869096 793 NQTLQKNLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 134 NRELREELAELK---QENEALEAENERLQENEQR 164
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
605-803 |
1.18e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 605 KIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKkITNLKITCEKIEALEQENSELERenrkykktldsfkn 684
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR-LAEYSWDEIDVASAEREIAELEA-------------- 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 685 ltfQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTE 764
Cdd:COG4913 676 ---ELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1378869096 765 NQRLQKALENSNKKI-QQLESELQDLEMENQTLQKNLEEL 803
Cdd:COG4913 753 ERFAAALGDAVERELrENLEERIDALRARLNRAEEELERA 792
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
247-408 |
1.24e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.77 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAVRVDKLE 326
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKE----------IKRLELEIEEVEARIKKYEEQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 327 SEVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1579 83 GNVRNNKEYealQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAELEELE 162
|
....*.
gi 1378869096 403 KKIEEL 408
Cdd:COG1579 163 AEREEL 168
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-935 |
1.33e-05 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 49.18 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNltfQLESLEKENSQLDEEN---LELRRNVESLkc 715
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSELskaILAKSKLEKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 716 asmkMAQLQLENKELESEKEQLKKGLE----LMKASFKKTeRLEVSYQGLDTENQRLQKALENSN--KKIQQL--ESELQ 787
Cdd:pfam09728 76 ----CRELQKQNKKLKEESKKLAKEEEekrkELSEKFQST-LKDIQDKMEEKSEKNNKLREENEElrEKLKSLieQYELR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 788 DLEMENQTLQKNLE----ELKISSKRLEQlEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIK-------DTTLEEN 855
Cdd:pfam09728 151 ELHFEKLLKTKELEvqlaEAKLQQATEEE-EKKAQEKEVAKARELKAQvQTLSETEKELREQLNLYvekfeefQDTLNKS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 856 NVKIGNLEKENKTLFKEIgiykescirlKELEKENKELVKRATIDIKTLVtlreDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:pfam09728 230 NEVFTTFKKEMEKMSKKI----------KKLEKENLTWKRKWEKSNKALL----EMAEERQKLKEELEKLQKKLEKLENL 295
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
602-786 |
1.35e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.77 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 602 KLSKIEFEKRQIRKELEHYKEkgeRAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTLDS 681
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPA---ELAELEDELAALEARLEAAKTELEDLE---KEIKRLELEIEEVEARIKKYEEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 682 FKN------LTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKKGLELMKASfkkterle 755
Cdd:COG1579 85 VRNnkeyeaLQKEIESLKRRISDLEDEILELMERIE----------ELEEELAELEAELAELEAELEEKKAE-------- 146
|
170 180 190
....*....|....*....|....*....|.
gi 1378869096 756 vsyqgLDTENQRLQKALENSNKKIQQLESEL 786
Cdd:COG1579 147 -----LDEELAELEAELEELEAEREELAAKI 172
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
466-867 |
1.40e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 50.29 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 466 EMENQSLTKTVEELRSTMDSAEGTTSKILKIEKENqrLSKKVEILENeiIQEKQSLQNcqnlskdlmkekAQLEKTIETL 545
Cdd:PLN02939 74 QLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAI--AAIDNEQQTN--SKDGEQLSD------------FQLEDLVGMI 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 546 ReNSERQIKILEQenehlnqtvsslrqrsqisaeARVKDIEKENKILHE------SIKETSSKLSKIEFEKRQIRKELEH 619
Cdd:PLN02939 138 Q-NAEKNILLLNQ---------------------ARLQALEDLEKILTEkealqgKINILEMRLSETDARIKLAAQEKIH 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 620 YKEKGERAEELENELHHlekENELLQKKITNLKitcEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQL 699
Cdd:PLN02939 196 VEILEEQLEKLRNELLI---RGATEGLCVHSLS---KELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 700 DeenlelrrnveslkcASMKmaqlQLENKELESEKEQLKKGLELMKASFKKTERLEVsyqgldtenqRLQKALENSNKKI 779
Cdd:PLN02939 270 D---------------ASLR----ELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD----------LLDRATNQVEKAA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 780 QQLESElQDLEMENQTLQKNLEE---LKISSKRLEQLEKENKSLEQetsqlekdkkQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:PLN02939 321 LVLDQN-QDLRDKVDKLEASLKEanvSKFSSYKVELLQQKLKLLEE----------RLQASDHEIHSYIQLYQESIKEFQ 389
|
410
....*....|.
gi 1378869096 857 VKIGNLEKENK 867
Cdd:PLN02939 390 DTLSKLKEESK 400
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
531-844 |
1.62e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 49.83 E-value: 1.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 531 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQtvsslrqrsqisaearvkdiEKENKILHESIKETSSKLSKIEFEK 610
Cdd:PRK04778 100 FRKAKHEINEIESLLDLIEEDIEQILEELQELLES--------------------EEKNREEVEQLKDLYRELRKSLLAN 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 611 R--------QIRKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNLKITCEKIEALEqenselerenRKYKKTL- 679
Cdd:PRK04778 160 RfsfgpaldELEKQLENLEEEFSQFVELTESGDYVEAREILdqLEEELAALEQIMEEIPELL----------KELQTELp 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 680 DSFKNLTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLE-----NKELESEKEQL-----------KKGL 741
Cdd:PRK04778 230 DQLQELKAGYRELVEEGYHLDHLDIekEIQDLKEQIDENLALLEELDLDeaeekNEEIQERIDQLydilerevkarKYVE 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 742 ELMKASFKKTERLEVSYQGLDTENQRLQKALENSNK---KIQQLESELQDLEMENQTLQKNL-----------EELKISS 807
Cdd:PRK04778 310 KNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESeleSVRQLEKQLESLEKQYDEITERIaeqeiayselqEELEEIL 389
|
330 340 350
....*....|....*....|....*....|....*..
gi 1378869096 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK04778 390 KQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNK 426
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
917-1119 |
1.72e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.44 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEEstnYNQQLRQEL 996
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELE-ALQAEIDKLQAEIAEAEAEIEE---RREELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 997 KTVKKN------YEALKQRQDEEKMVQSSppvsgedNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQ 1070
Cdd:COG3883 93 RALYRSggsvsyLDVLLGSESFSDFLDRL-------SALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1378869096 1071 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS 1119
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-681 |
1.73e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 1.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 464 KLEMENQSLTKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLqncqnlsKDLMKEKAQLEKTIE 543
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL-------AELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEK 623
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 624 GERAEELENELHHLEKENELLQKKITnlkitcEKIEALEQENSELERENRKYKKTLDS 681
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELEALIAR 231
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
243-651 |
1.78e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.94 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 243 TESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARmyRDELDALREKAVRV 322
Cdd:COG1196 322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA--EELLEALRAAAELA 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 323 DKLESEVSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1196 400 AQLEELEEAEEALLERLE---RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 403 KKIEELMEE--------NMTLEMAQKQSMDES-------------------LHLGWE----------------------- 432
Cdd:COG1196 477 AALAELLEElaeaaarlLLLLEAEADYEGFLEgvkaalllaglrglagavaVLIGVEaayeaaleaalaaalqnivvedd 556
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 433 ----------------------LEQISRTSELSEAPQKSLGHEVNELTSSRL---------------------LKLEMEN 469
Cdd:COG1196 557 evaaaaieylkaakagratflpLDKIRARAALAAALARGAIGAAVDLVASDLreadaryyvlgdtllgrtlvaARLEAAL 636
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 470 QSLTKTVEELRSTmdSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQSLQncqnLSKDLMKEKAQLEKTIETLRENS 549
Cdd:COG1196 637 RRAVTLAGRLREV--TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER----LAEEELELEEALLAEEEEERELA 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVK-----DIEKENKILHESIKETSSKLSKIefeKRQIRK-------EL 617
Cdd:COG1196 711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEeelleEEALEELPEPPDLEELERELERL---EREIEAlgpvnllAI 787
|
490 500 510
....*....|....*....|....*....|....
gi 1378869096 618 EHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:COG1196 788 EEYEELEERYDFLSEQREDLEEARETLEEAIEEI 821
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
692-837 |
2.50e-05 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 46.14 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 692 LEKENSQLDEENLElrrnveslkcasMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKA 771
Cdd:pfam12718 7 LEAENAQERAEELE------------EKVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTN 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 772 LENSNKKIQQLEselQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 75 NENLTRKIQLLE---EELEESDKRLKETTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
638-940 |
2.65e-05 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 49.45 E-value: 2.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 638 EKENELLQKKITNLKIT----CEKIEALEQENSELERENRKYKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRR 708
Cdd:PRK00448 1 NEMQEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 709 NVESLKCasmkmaQLQLENKELESEKEQLKKGLELMKASFKKTE------RLEVSYQGlDTENQRL-QKALENSNKKIQQ 781
Cdd:PRK00448 81 EVENITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 782 LESELqdLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KD 849
Cdd:PRK00448 154 FGFGI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 850 TTLEENNVKI-GNL------EKENKTLFKEIGI--YKEScIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQ 919
Cdd:PRK00448 232 INEEERRVVVeGYVfkveikELKSGRHILTFKItdYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDL 310
|
330 340
....*....|....*....|..
gi 1378869096 920 QMN-NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 311 VMNaQDINEIKHPERKDTAEEE 332
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
257-586 |
2.74e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 2.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 257 KAKIRRLRQELEEKTEQlLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRD-ELDALREKAvrvDKLESEVSRYKER 335
Cdd:pfam17380 295 KMEQERLRQEKEEKARE-VERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERErELERIRQEE---RKRELERIRQEEI 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 336 LHDIEfykaRVEELKEDNQVLLETKTMLEDQLEGtrARSDKLHELEKenlQLKAKLHDMEMERdmDRKKIEELMEENM-T 414
Cdd:pfam17380 371 AMEIS----RMRELERLQMERQQKNERVRQELEA--ARKVKILEEER---QRKIQQQKVEMEQ--IRAEQEEARQREVrR 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 415 LEMAQKQSMDESlhlgwELEQISRTSELSEAPQKSlghevnelTSSRLLKLEME-NQSLTKTVEELRSTMDSAEGTTSKI 493
Cdd:pfam17380 440 LEEERAREMERV-----RLEEQERQQQVERLRQQE--------EERKRKKLELEkEKRDRKRAEEQRRKILEKELEERKQ 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 494 LKIEKENQR--LSKKVEILENEIIQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSERqIKILEQENEHLNQTVSSL 570
Cdd:pfam17380 507 AMIEEERKRklLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVESE 585
|
330
....*....|....*.
gi 1378869096 571 RQRSQISAEARVKDIE 586
Cdd:pfam17380 586 KARAEYEATTPITTIK 601
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
256-846 |
2.76e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 49.57 E-value: 2.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 256 AKAKIRRLRqeleekTEQLLDckQELEQMEIELKRLQQEnmnLLSDARSARMyrdeLDALREKAVRVDKLESEVSRYKER 335
Cdd:PRK04863 498 ARELLRRLR------EQRHLA--EQLQQLRMRLSELEQR---LRQQQRAERL----LAEFCKRLGKNLDDEDELEQLQEE 562
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 336 LHdiefykARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLK---AKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PRK04863 563 LE------ARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQdalARLREQSGEEFEDSQDVTEYMQQL 636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 413 MTLEMAQKQSMDESLHLGWELE-QISRTS--ELSEAPQ-KSL-----GHEVNEL-----------TSSRLLKLEmeNQSL 472
Cdd:PRK04863 637 LERERELTVERDELAARKQALDeEIERLSqpGGSEDPRlNALaerfgGVLLSEIyddvsledapyFSALYGPAR--HAIV 714
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 473 TKTVEELRSTMDSAEGTTSKILKIEKENQRL---SKKVEILENEIIQEKQSLQ------------NCQNLSKDLMKEKAQ 537
Cdd:PRK04863 715 VPDLSDAAEQLAGLEDCPEDLYLIEGDPDSFddsVFSVEELEKAVVVKIADRQwrysrfpevplfGRAAREKRIEQLRAE 794
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 538 LEKTIETLRENSERQIKiLEQENEHLNQTVSSlrqRSQISAEArvkDIEKENKILHESIKETSSKLSKIEFEKRQIRKEL 617
Cdd:PRK04863 795 REELAERYATLSFDVQK-LQRLHQAFSRFIGS---HLAVAFEA---DPEAELRQLNRRRVELERALADHESQEQQQRSQL 867
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 618 EHYKEK-------------------GERAEELENELHHLEKEN----------ELLQKKITNLKITCEKIEALEQENSEL 668
Cdd:PRK04863 868 EQAKEGlsalnrllprlnlladetlADRVEEIREQLDEAEEAKrfvqqhgnalAQLEPIVSVLQSDPEQFEQLKQDYQQA 947
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 669 ERENRKYKKTLDSFKNLTFQLESLEKENSQ-LDEENLELrrnVESLKcasmkmAQLqlenKELESEKEQLKKGLELMKAS 747
Cdd:PRK04863 948 QQTQRDAKQQAFALTEVVQRRAHFSYEDAAeMLAKNSDL---NEKLR------QRL----EQAEQERTRAREQLRQAQAQ 1014
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 748 FkkTERLEVsYQGLDTENQRLQKALensnkkiQQLESELQDL------EMENQ------TLQKNLEElkiSSKRLEQLEK 815
Cdd:PRK04863 1015 L--AQYNQV-LASLKSSYDAKRQML-------QELKQELQDLgvpadsGAEERararrdELHARLSA---NRSRRNQLEK 1081
|
650 660 670
....*....|....*....|....*....|.
gi 1378869096 816 ENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK04863 1082 QLTFCEAEMDNLTKKLRKLERDYHEMREQVV 1112
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-713 |
2.96e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 498 KENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKILEQENEHLNQTVSSLRQRsqis 577
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKE---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 578 AEARVKDIEKENKILHESIKE--TSSKLSKIEF-----EKRQIRKELEHYK----EKGERAEELENELHHLEKENELLQK 646
Cdd:COG4942 92 IAELRAELEAQKEELAELLRAlyRLGRQPPLALllspeDFLDAVRRLQYLKylapARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 647 KITNLKitcEKIEALEQENSELERENRKYKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVESL 713
Cdd:COG4942 172 ERAELE---ALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARL 232
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
3.22e-05 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 46.46 E-value: 3.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 719 KMAQLQLENKELESEKEQLKKGLELMKASfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 799 NLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKenktlfkeigiyke 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQDLQDELVALQLQLNMAEE-------------- 148
|
170
....*....|....*...
gi 1378869096 879 sciRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
343-572 |
3.26e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.86 E-value: 3.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdmemerdmdRKKIEELMEENMTLEMAQKQS 422
Cdd:PHA02562 173 KDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARK-------------QNKYDELVEEAKTIKAEIEEL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 423 MDESLHLgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-------QSLTKT---VEELRSTMDSAEGTTSK 492
Cdd:PHA02562 240 TDELLNL--VMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptctQQISEGpdrITKIKDKLKELQHSLEK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 493 IL-KIEKENQR------LSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTietlRENSERQIKILEQENEHLNQ 565
Cdd:PHA02562 318 LDtAIDELEEImdefneQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAE----FVDNAEELAKLQDELDKIVK 393
|
....*..
gi 1378869096 566 TVSSLRQ 572
Cdd:PHA02562 394 TKSELVK 400
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-368 |
3.42e-05 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 48.92 E-value: 3.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmNLLSDARSARmYRDELDALREKAvrvDKLESEVSRYKERLHDIEF 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEEEL---EALKARWEAEKELIEEIQE 475
|
90 100
....*....|....*....|....*..
gi 1378869096 342 YKARVEELKEDNQVLLETKTMLEDQLE 368
Cdd:COG0542 476 LKEELEQRYGKIPELEKELAELEEELA 502
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
974-1382 |
3.49e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 48.68 E-value: 3.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 974 KIAALEARLEEStnYNQQLRQELKTVKKnyeaLKQR-QDEEKMvqssppvsgedNKWERESQE-TTRELLKVKDRLIEVE 1051
Cdd:PRK04778 30 RIDELEERKQEL--ENLPVNDELEKVKK----LNLTgQSEEKF-----------EEWRQKWDEiVTNSLPDIEEQLFEAE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1052 RNNAT--LQAEKQALKT---QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQvenSTLNSQSTS------- 1119
Cdd:PRK04778 93 ELNDKfrFRKAKHEINEiesLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSfgpalde 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1120 LMNQNAQLLIQQSSLENENES--VIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLIAKhgtLKSAHKNLEVE- 1193
Cdd:PRK04778 170 LEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAaleQIMEEIPELLKELQTELPDQLQE---LKAGYRELVEEg 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1194 ----HKDLEDRYNQLLKQKGQLEDLEKTLKVEQekmlLKNKNHETvaaeykklcgeNDRLNHTYNQLLKETE---VLQTD 1266
Cdd:PRK04778 247 yhldHLDIEKEIQDLKEQIDENLALLEELDLDE----AEEKNEEI-----------QERIDQLYDILEREVKarkYVEKN 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1267 HKNLKSLLNSSRLEQTRLEAEFSKLKEQYQqldITSTKLNNQCELLSQLKgNLEEENRHLLDQI--QTL---MLQNRtlL 1341
Cdd:PRK04778 312 SDTLPDFLEHAKEQNKELKEEIDRVKQSYT---LNESELESVRQLEKQLE-SLEKQYDEITERIaeQEIaysELQEE--L 385
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1378869096 1342 EQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKImDQYKF 1382
Cdd:PRK04778 386 EEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKL-ERYRN 425
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
3.65e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 47.23 E-value: 3.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1378869096 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI-GIYKESCIRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELdEELAELEAELEELEAEREELAAK 171
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
596-826 |
3.86e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 3.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 596 IKETSSKLSKIEFEKRQIRKELehyKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQE----NSELERE 671
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAEL---DALQAELEELNEEYNELQAELEALQAEIDKLQ---AEIAEAEAEieerREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 672 NRKYKKTLDSFKNLTFQLESlekensqldeENL-ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLElmkasfKK 750
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGS----------ESFsDFLDRLSALSKIADADADLLEELKADKAELEAKKAELE------AK 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 751 TERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:COG3883 156 LAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1183-1375 |
4.04e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.78 E-value: 4.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1183 LKSAHKNLEVehkdLEDRYNQLLKQKGQLE-DLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETE 1261
Cdd:COG1196 181 LEATEENLER----LEDILGELERQLEPLErQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1262 VLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLL 1341
Cdd:COG1196 257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336
|
170 180 190
....*....|....*....|....*....|....
gi 1378869096 1342 EQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1375
Cdd:COG1196 337 EELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-967 |
4.27e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.77 E-value: 4.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 729 ELESEKEQLKKGLELMKASFKKT-----ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTlEENNVKIGNLEKENKTLFKEIGIYKES 879
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDK-GYVYVVVVVLKELSDEVEEELKKLGFE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 880 CIRLKElEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhDEQSTDDRYKLLE-- 957
Cdd:PRK05771 204 RLELEE-EGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEAL-SKFLKTDKTFAIEgw 281
|
250
....*....|....*.
gi 1378869096 958 ------SKLESTLKKS 967
Cdd:PRK05771 282 vpedrvKKLKELIDKA 297
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
956-1154 |
4.28e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 956 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKknyEALKQRQDE-EKMVQSSPPVSGEDNKWER--E 1032
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE---AEIEERREElGERARALYRSGGSVSYLDVllG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1033 SQETTrELLkvkDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST 1112
Cdd:COG3883 111 SESFS-DFL---DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQ 186
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1378869096 1113 LNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDS 1154
Cdd:COG3883 187 LSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAA 228
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
716-873 |
4.36e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 4.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 716 ASMKMAQLQLENKELESEKEQLKKglelmkasfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQT 795
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQA----------ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 796 LQKNLEEL----------------------------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:COG3883 84 RREELGERaralyrsggsvsyldvllgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190
....*....|....*....|....*....|....*
gi 1378869096 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQL 198
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
839-1012 |
4.55e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.84 E-value: 4.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 839 KRLRQQAEIkDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKT 918
Cdd:COG1579 7 RALLDLQEL-DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 919 QQMNNDLEKLTHELEKIGLNKERLlhdeqstDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTnynQQLRQELKT 998
Cdd:COG1579 85 VRNNKEYEALQKEIESLKRRISDL-------EDEILELMERIE-ELEEELAELEAELAELEAELEEKK---AELDEELAE 153
|
170
....*....|....
gi 1378869096 999 VKKNYEALKQRQDE 1012
Cdd:COG1579 154 LEAELEELEAEREE 167
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
499-852 |
4.78e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 48.80 E-value: 4.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 499 ENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLektietlrenSERQiKILEQE----NEHLNQTVSSLRQRS 574
Cdd:COG3096 279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEEL----------SARE-SDLEQDyqaaSDHLNLVQTALRQQE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 575 QIsaEARVKDIEKENKIL---HESIKETSSKLSKIEFEKRQIRKELEHYK-----------EKGERAEELENELHHLEKE 640
Cdd:COG3096 348 KI--ERYQEDLEELTERLeeqEEVVEEAAEQLAEAEARLEAAEEEVDSLKsqladyqqaldVQQTRAIQYQQAVQALEKA 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 641 NELLQK---KITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQ-LESLEK-----ENSQLDEENLELRRNVE 711
Cdd:COG3096 426 RALCGLpdlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKaYELVCKiagevERSQAWQTARELLRRYR 505
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKT-------ERLEVSYQGLDTENQRLQKALENSNKKIQQLES 784
Cdd:COG3096 506 SQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIgqqldaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 785 ELQDLEMENQTL----------QKNLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLR 842
Cdd:COG3096 586 QLEQLRARIKELaarapawlaaQDALERLReqsgealadsqeVTAAMQQLLERE-REATVERDELAARKQALESQIERLS 664
|
410
....*....|
gi 1378869096 843 QQAEIKDTTL 852
Cdd:COG3096 665 QPGGAEDPRL 674
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1195-1376 |
4.95e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 48.23 E-value: 4.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1195 KDLEDRYNQLLKQKG--------QLEDLEKTLKVEQEKMllknknhetvaAEYKKLCGENDRLNHTYNQLLKETEVLQTD 1266
Cdd:COG4717 49 ERLEKEADELFKPQGrkpelnlkELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELREE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1267 HKNLKSLLNSSRLEQTR--LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1344
Cdd:COG4717 118 LEKLEKLLQLLPLYQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL 197
|
170 180 190
....*....|....*....|....*....|..
gi 1378869096 1345 MESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1376
Cdd:COG4717 198 AEELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-896 |
5.44e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.24 E-value: 5.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 706 LRRNVESLKCASMK-MAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLL---QKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 785 ELQDLEmenqtlqknleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-IKDTTLEE-NNVKIGNL 862
Cdd:PRK12704 101 KLELLE-----------------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErISGLTAEEaKEILLEKV 163
|
170 180 190
....*....|....*....|....*....|....
gi 1378869096 863 EKENKTlfkeigiykESCIRLKELEKENKELVKR 896
Cdd:PRK12704 164 EEEARH---------EAAVLIKEIEEEAKEEADK 188
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
749-1379 |
6.77e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.12 E-value: 6.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 749 KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLemenQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE 828
Cdd:TIGR00606 200 QKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIV----KSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALK 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 829 KDKKQLEKENKRLRQQAEIKDTTLEEnnvKIGNLEKENKTLFKEIGIYKESCIRlkELEKENKELVKRATIDIKTLVTL- 907
Cdd:TIGR00606 276 SRKKQMEKDNSELELKMEKVFQGTDE---QLNDLYHNHQRTVREKERELVDCQR--ELEKLNKERRLLNQEKTELLVEQg 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 908 REDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN 987
Cdd:TIGR00606 351 RLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADE 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 988 YNQQLRQELKTVKKNYEALKQRQDEEKMVQSSppvsgednkwERESQETTRELLKVKDRLIEVERNNAtlQAEKQALKTQ 1067
Cdd:TIGR00606 431 IRDEKKGLGRTIELKKEILEKKQEELKFVIKE----------LQQLEGSSDRILELDQELRKAERELS--KAEKNSLTET 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1068 LKQLETQNNNLQAQILALQRQTVSLQEQ---NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQS----SLENENES 1140
Cdd:TIGR00606 499 LKKEVKSLQNEKADLDRKLRKLDQEMEQlnhHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpNKKQLEDW 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1141 VIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLeVEHKDLEDRYNQLLKQKGQLEDLEKTLKV 1220
Cdd:TIGR00606 579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL-FDVCGSQDEESDLERLKEEIEKSSKQRAM 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1221 EQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQllketevLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDI 1300
Cdd:TIGR00606 658 LAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAE-------LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLG 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1301 TSTKLNNQCELLSQLKGNLEEENRHLLDQIQTL---MLQNRTLLEQNMESKDLFHVEQRQyIDKLNELRRQKEKLEEKIM 1377
Cdd:TIGR00606 731 LAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLkndIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKIA 809
|
..
gi 1378869096 1378 DQ 1379
Cdd:TIGR00606 810 QQ 811
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
656-898 |
6.89e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.21 E-value: 6.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 656 EKIEALEQENSELERENRKYKKTLDSFKNLTFQL-ESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Cdd:COG1340 8 SSLEELEEKIEELREEIEELKEKRDELNEELKELaEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 735 EQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSN----------KKIQQLESELQDLEME---NQTLQKNLE 801
Cdd:COG1340 88 NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKAlekNEKLKELRA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESci 881
Cdd:COG1340 168 ELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKE-- 245
|
250
....*....|....*..
gi 1378869096 882 rLKELEKENKELVKRAT 898
Cdd:COG1340 246 -LKKLRKKQRALKREKE 261
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
7.03e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 46.78 E-value: 7.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLFKEIGIYKesciRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 1378869096 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
768-872 |
7.53e-05 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 47.03 E-value: 7.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 768 LQKALENSNKKIQQLESELQDLEMENQTLQknleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEi 847
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENEELE----------SELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFE- 201
|
90 100
....*....|....*....|....*
gi 1378869096 848 kdTTLEENNVKIGNLEKENKTLFKE 872
Cdd:COG4026 202 --ELLKKRLLEVFSLEELWKELFPE 224
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1013 |
8.11e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.20 E-value: 8.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 734 KEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLemeNQTLQKNLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKElEKENKEL 893
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE-AEAEQAL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEE 973
Cdd:COG4372 186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELEL 265
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1378869096 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEE 1013
Cdd:COG4372 266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLA 305
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
262-854 |
8.28e-05 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 47.82 E-value: 8.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQ----QENMNLLSDARsarmyrdELDALrekAVRVDKLESEVSRYKERLH 337
Cdd:pfam07111 56 EGSQALSQQAELISRQLQELRRLEEEVRLLRetslQQKMRLEAQAM-------ELDAL---AVAEKAGQAEAEGLRAALA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 338 DIEFYKARVEELKEdnQVLLETKTMLEDQLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKieelmeenmtLE 416
Cdd:pfam07111 126 GAEMVRKNLEEGSQ--RELEEIQRLHQEQLSSlTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQ----------LA 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 417 MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRllKLEMENQSLTKTVEELRSTMDSAEGT------- 489
Cdd:pfam07111 194 EAQKEAELLRKQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHSQ--TWELERQELLDTMQHLQEDRADLQATvellqvr 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 490 ----TSKILKIEKENQRLSKKVEILENEIIQEKQSLQNcqNLSKDLMKEKAQLeKTIETLRENSERQIKILEQEnehLNQ 565
Cdd:pfam07111 272 vqslTHMLALQEEELTRKIQPSDSLEPEFPKKCRSLLN--RWREKVFALMVQL-KAQDLEHRDSVKQLRGQVAE---LQE 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 566 TVSSLRQRSQISAEArVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEkgeraeELENELHHLEKENELLQ 645
Cdd:pfam07111 346 QVTSQSQEQAILQRA-LQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEE------QLKFVVNAMSSTQIWLE 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 646 KKITNLKITCEKIEALeqeNSELERENRKYKkTLDSFKNLTFQLESLEKENSQLDEENLELRrnveslkcasmkmAQLQL 725
Cdd:pfam07111 419 TTMTRVEQAVARIPSL---SNRLSYAVRKVH-TIKGLMARKVALAQLRQESCPPPPPAPPVD-------------ADLSL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 726 ENKELESEKEQLKKGLELmKASFKKTERLEVSYQGlDTENQRLqkalensNKKIQQLESELQDLEmenQTLQKNLEELKI 805
Cdd:pfam07111 482 ELEQLREERNRLDAELQL-SAHLIQQEVGRAREQG-EAERQQL-------SEVAQQLEQELQRAQ---ESLASVGQQLEV 549
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 806 SSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN-----KRLRQQAEIKDTTLEE 854
Cdd:pfam07111 550 ARQGQQESTEEAASLRQELTQQQEIYGQALQEKvaeveTRLREQLSDTKRRLNE 603
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
548-822 |
8.31e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 8.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 548 NSERQIKILEQENEHLNQTVSslrqrsqiSAEARVKDIEKENKILHEsIKETSSKLSKIEFEK---RQIRKELehykekg 624
Cdd:COG4913 607 DNRAKLAALEAELAELEEELA--------EAEERLEALEAELDALQE-RREALQRLAEYSWDEidvASAEREI------- 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 625 eraEELENELHHLEKEN---ELLQKKITNLKitcEKIEALEQENSELERENRKYKKTLDSF----KNLTFQLESLEKENS 697
Cdd:COG4913 671 ---AELEAELERLDASSddlAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQAeeelDELQDRLEAAEDLAR 744
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 698 QLDEENLELRRNVESLKCASMKM-AQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTEN----QRLQKAL 772
Cdd:COG4913 745 LELRALLEERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESlpeyLALLDRL 824
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 773 ENSN-----KKIQQL--ESELQDLEMENQTLQKNLEELKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 825 EEDGlpeyeERFKELlnENSIEFVADLLSKLRRAIREIK------ERIDPLNDSLKR 875
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
494-852 |
8.46e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.03 E-value: 8.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 494 LKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQL---EKTIET----------LRENSERQIKILEQEN 560
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELneaESDLEQdyqaasdhlnLVQTALRQQEKIERYQ 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 561 EHLNQTVSSLRQRSQISAEARVKDIEKENK--ILHESIKETSSKLSK-----IEFEKRQIrkELEHYKEKGERAEELeNE 633
Cdd:PRK04863 355 ADLEELEERLEEQNEVVEEADEQQEENEARaeAAEEEVDELKSQLADyqqalDVQQTRAI--QYQQAVQALERAKQL-CG 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 634 LHHLEKEN--ELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESlekenSQLDEENLELRRNVE 711
Cdd:PRK04863 432 LPDLTADNaeDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSR-----SEAWDVARELLRRLR 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 712 SLKCASMKMAQLQLENKELESEKEQlKKGLELMKASFKKteRLEVSYQG---LDTENQRLQKALENSN------------ 776
Cdd:PRK04863 507 EQRHLAEQLQQLRMRLSELEQRLRQ-QQRAERLLAEFCK--RLGKNLDDedeLEQLQEELEARLESLSesvsearerrma 583
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 777 --KKIQQLESELQDLEM---ENQTLQKNLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENK 839
Cdd:PRK04863 584 lrQQLEQLQARIQRLAArapAWLAAQDALARLReqsgeefedsqdVTEYMQQLLERE-RELTVERDELAARKQALDEEIE 662
|
410
....*....|...
gi 1378869096 840 RLRQQAEIKDTTL 852
Cdd:PRK04863 663 RLSQPGGSEDPRL 675
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
554-670 |
9.49e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.47 E-value: 9.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 554 KILEQENEHLNQTVSSLRQRSQISAEARVKDI-----EKENKILHESIKETSSKLSKI-EFEKRQIRKElEHYKEKGERA 627
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEAlleakEEIHKLRNEFEKELRERRNELqKLEKRLLQKE-ENLDRKLELL 105
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1378869096 628 EELENELHHLEKENELLQKKITNLKITCEKIEalEQENSELER 670
Cdd:PRK12704 106 EKREEELEKKEKELEQKQQELEKKEEELEELI--EEQLQELER 146
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
9.51e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.13 E-value: 9.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNL---------LSDARSARMYR-----DEL 312
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAeaeieerreELGERARALYRsggsvSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 313 DALrekavrvdkLESE-VSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKE 383
Cdd:COG3883 106 DVL---------LGSEsFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQ 176
|
170 180 190
....*....|....*....|....*....|....*....
gi 1378869096 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
507-711 |
9.53e-05 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 47.54 E-value: 9.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 507 VEILENEIIQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRE-----------NSERQIKILEQENEHLNQTVSSLRQRS 574
Cdd:pfam06160 181 LEKLEEETDALEELMEDIPPLYEELKTElPDQLEELKEGYREmeeegyalehlNVDKEIQQLEEQLEENLALLENLELDE 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 575 qisAEARVKDIEKE--------------NKILHESIKETSSKLSKIEFEKRQIRKELEHYK-------EKGERAEELENE 633
Cdd:pfam06160 261 ---AEEALEEIEERidqlydllekevdaKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQqsytlneNELERVRGLEKQ 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 634 LHHLEKENELLQKKITNLKIT----CEKIEALEQENSELERENRKYKKTLDSfknltfqLESLEKEN----SQLDEENLE 705
Cdd:pfam06160 338 LEELEKRYDEIVERLEEKEVAyselQEELEEILEQLEEIEEEQEEFKESLQS-------LRKDELEAreklDEFKLELRE 410
|
....*.
gi 1378869096 706 LRRNVE 711
Cdd:pfam06160 411 IKRLVE 416
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
659-1009 |
1.20e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.82 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 659 EALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN------EQLQAAQAELAQAQEELE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 739 KGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK 818
Cdd:COG4372 105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKENKELVKRAT 898
Cdd:COG4372 185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 899 IDIktlvtlREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL 978
Cdd:COG4372 265 LAI------LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAE 338
|
330 340 350
....*....|....*....|....*....|.
gi 1378869096 979 EARLEESTNYNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4372 339 LADLLQLLLVGLLDNDVLELLSKGAEAGVAD 369
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
599-924 |
1.37e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 46.34 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 599 TSSKLSKIEFEKRQIRKELEHYKEKgeraeELENELHHLEKENELLQKKITNLKITCEKIEAleqenselerenrKYKKT 678
Cdd:pfam15905 52 TARKVKSLELKKKSQKNLKESKDQK-----ELEKEIRALVQERGEQDKRLQALEEELEKVEA-------------KLNAA 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 679 LDSFKNLTFQLESLEKENSQLDEENlELRRNVESLKCASMKMAQLQLENKELESEKEQLkkglelMKASFKKTERLEVSY 758
Cdd:pfam15905 114 VREKTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLEAK------MKEVMAKQEGMEGKL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 759 QgldtenqRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam15905 187 Q-------VTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEI 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 839 KRLRQQAEIKDTTLEENnvkignlekenktlfkeigiYKESCIRLKELEKENKELVKRATIDIKTLV----TLREDLVSE 914
Cdd:pfam15905 260 ESLKQSLEEKEQELSKQ--------------------IKDLNEKCKLLESEKEELLREYEEKEQTLNaeleELKEKLTLE 319
|
330
....*....|
gi 1378869096 915 KLKTQQMNND 924
Cdd:pfam15905 320 EQEHQKLQQK 329
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-867 |
1.41e-04 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 43.54 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|.
gi 1378869096 857 VKIGNLEKENK 867
Cdd:pfam04871 81 LLLGDLEEKVE 91
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
656-859 |
1.53e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 656 EKIEALEQENSELERENRKYKKTLDSF------KNLTFQLESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLEN-- 727
Cdd:COG3206 182 EQLPELRKELEEAEAALEEFRQKNGLVdlseeaKLLLQQLSELESQLAEARAELAEAEARLAALR-AQLGSGPDALPEll 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 728 -----KELESEKEQLKKGLELMKASFKKTERlevSYQGLDTENQRLQKALENSNKKI-QQLESELQDLEMENQTLQKNLE 801
Cdd:COG3206 261 qspviQQLRAQLAELEAELAELSARYTPNHP---DVIALRAQIAALRAQLQQEAQRIlASLEAELEALQAREASLQAQLA 337
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 802 ELKISSKRLEQLEKENKSLEQEtsqLEKDKKQLEKENKRLrQQAEIkDTTLEENNVKI 859
Cdd:COG3206 338 QLEARLAELPELEAELRRLERE---VEVARELYESLLQRL-EEARL-AEALTVGNVRV 390
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-869 |
1.60e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.00 E-value: 1.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 779 IQQLESELQDLEMENQTLQKnlEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|.
gi 1378869096 859 IGNLEKENKTL 869
Cdd:COG0542 487 IPELEKELAEL 497
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
203-573 |
1.75e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.87 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 203 ERDEHSETIIELSEErdglhfpphasssaqspcgspgmkRTESRQhlsvELADAKAKIRRLRQELEEKTEQLLDCKQELE 282
Cdd:COG3096 279 ERRELSERALELRRE------------------------LFGARR----QLAEEQYRLVEMARELEELSARESDLEQDYQ 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 283 QMEIELKRLQqenmNLLSDARSARMYRDELDALREKAVR----VDKLESEVSRYKERLHDIEfykARVEELKE---DNQV 355
Cdd:COG3096 331 AASDHLNLVQ----TALRQQEKIERYQEDLEELTERLEEqeevVEEAAEQLAEAEARLEAAE---EEVDSLKSqlaDYQQ 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 356 LLETKTMLEDQ-------LEGTRARSDkLHELEKENL-----QLKAKlhdmemERDMDRKKIEelMEENMTLEMAQKQSM 423
Cdd:COG3096 404 ALDVQQTRAIQyqqavqaLEKARALCG-LPDLTPENAedylaAFRAK------EQQATEEVLE--LEQKLSVADAARRQF 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 424 DESLHLgweLEQISRTSELSEAPQKSlghevneltssrllklemenQSLTKTVEELRSTMDSAEGTTSKILKIEKENQRL 503
Cdd:COG3096 475 EKAYEL---VCKIAGEVERSQAWQTA--------------------RELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQ 531
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 504 SKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKiLEQENEHLNQTVSSLRQR 573
Cdd:COG3096 532 QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSE-LRQQLEQLRARIKELAAR 600
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
883-1120 |
1.86e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 46.55 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 883 LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQmnndleKLTHELEKigLNKERLlhdeqstdDRYkllESKLES 962
Cdd:PHA02562 165 LSEMDKLNKDKIRELNQQIQTL-DMKIDHIQQQIKTYN------KNIEEQRK--KNGENI--------ARK---QNKYDE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 963 TLKKSLEIK------EEKIAALEARLEESTNYNQQLRQELKTVKKNyeaLKQRQDEEKMVQS-------SPPVSGEDNKW 1029
Cdd:PHA02562 225 LVEEAKTIKaeieelTDELLNLVMDIEDPSAALNKLNTAAAKIKSK---IEQFQKVIKMYEKggvcptcTQQISEGPDRI 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1030 ER------ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1103
Cdd:PHA02562 302 TKikdklkELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEEL 381
|
250
....*....|....*..
gi 1378869096 1104 AKLQVENSTLNSQSTSL 1120
Cdd:PHA02562 382 AKLQDELDKIVKTKSEL 398
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
758-1388 |
2.19e-04 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 46.61 E-value: 2.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 758 YQGLDTENQRLQKALENSNKKIQQLESELqdlEMENQTLQKNLEELKISSKRLEQLEKENkSLEQETSQLEKDKKQLEKE 837
Cdd:COG5022 812 YRSYLACIIKLQKTIKREKKLRETEEVEF---SLKAEVLIQKFGRSLKAKKRFSLLKKET-IYLQSAQRVELAERQLQEL 887
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 838 NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKESCIRLKELEKEnkelvkratIDIKTLVTLREDLVSEKLK 917
Cdd:COG5022 888 KIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNN---------IDLEEGPSIEYVKLPELNK 958
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 918 TQQMNNDLEKLTHELEkiglnkeRLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALE--ARLEESTNYNQQLRQE 995
Cdd:COG5022 959 LHEVESKLKETSEEYE-------DLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQEstKQLKELPVEVAELQSA 1031
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 996 LKTVKKNYEALKQRQDEEKMV--------QSSPPV--------SGEDNKWERESQETTRELLK-VKDRLIEVernnATLQ 1058
Cdd:COG5022 1032 SKIISSESTELSILKPLQKLKgllllennQLQARYkalklrreNSLLDDKQLYQLESTENLLKtINVKDLEV----TNRN 1107
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1059 AEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL-----MNQNAQLLIQQSS 1133
Cdd:COG5022 1108 LVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPspppfAALSEKRLYQSAL 1187
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1134 LENENESVIKEREDLKSLYDSLIKDH-EKLELLHERQASEYESLIAkHGTLKSAHKNLEVEHKDLEDRY---NQLLKQKG 1209
Cdd:COG5022 1188 YDEKSKLSSSEVNDLKNELIALFSKIfSGWPRGDKLKKLISEGWVP-TEYSTSLKGFNNLNKKFDTPASmsnEKLLSLLN 1266
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1210 QLEDLEKTLKVEQEKMllknknHETVAAEYKKLcgeNDRLnhtYNQL-LKETEVLQTDHKNLKslLNSSRLEQTRLEAEF 1288
Cdd:COG5022 1267 SIDNLLSSYKLEEEVL------PATINSLLQYI---NVGL---FNALrTKASSLRWKSATEVN--YNSEELDDWCREFEI 1332
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1289 SKLKEQYQQL----DITSTKLNNqcelLSQLKGNLEEENRHLLDQIQTLMLQ-NRTLLEQNMESKDLFHVEQRQYIDKLN 1363
Cdd:COG5022 1333 SDVDEELEELiqavKVLQLLKDD----LNKLDELLDACYSLNPAEIQNLKSRyDPADKENNLPKEILKKIEALLIKQELQ 1408
|
650 660
....*....|....*....|....*
gi 1378869096 1364 ELRRQKEKLEEKIMDQYKFYDPSPP 1388
Cdd:COG5022 1409 LSLEGKDETEVHLSEIFSEEKSLIS 1433
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
529-822 |
2.47e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.29 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 529 KDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRsqisaearVKDIEKENKILHESIKETSSKLSK 605
Cdd:COG1340 11 EELEEKIEELREEIEELKEKRDElneELKELAEKRDELNAQVKELREE--------AQELREKRDELNEKVKELKEERDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 606 IEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKtldsfknl 685
Cdd:COG1340 83 LNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELVEKIKELEKELEKAKK-------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 686 tfqLESLEKENSQLDEENLELRRNVESLkcasmkmaqlqleNKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTEN 765
Cdd:COG1340 155 ---ALEKNEKLKELRAELKELRKEAEEI-------------HKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEI 218
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 766 QRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKiSSKRLEQLEKENKSLEQ 822
Cdd:COG1340 219 VEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALK-REKEKEELEEKAEEIFE 274
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-854 |
2.64e-04 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 42.21 E-value: 2.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK------------SLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKvykligdvlvkqDKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90
....*....|
gi 1378869096 845 AEIKDTTLEE 854
Cdd:pfam01920 82 LEKLEKELEE 91
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
736-844 |
2.73e-04 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 44.13 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 736 QLKKGLELMKASFKKTERLevsYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKnleelkiSSKRLEQLEK 815
Cdd:pfam13851 30 SLKEEIAELKKKEERNEKL---MSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKDKQSLKN-------LKARLKVLEK 99
|
90 100
....*....|....*....|....*....
gi 1378869096 816 ENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam13851 100 ELKDLKWEHEVLEQRFEKVERERDELYDK 128
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
556-794 |
3.00e-04 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 45.30 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 556 LEQENEHLNQTVSSLRQRSQiSAEARVKDI-EKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGE----RAEEL 630
Cdd:pfam00038 23 LEQQNKLLETKISELRQKKG-AEPSRLYSLyEKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYEdelnLRTSA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 631 ENELHHLEKE-NEL------LQKKITNLKitcEKIEALEQENSELERENRKY--------------KKTLDS-FKNLTFQ 688
Cdd:pfam00038 102 ENDLVGLRKDlDEAtlarvdLEAKIESLK---EELAFLKKNHEEEVRELQAQvsdtqvnvemdaarKLDLTSaLAEIRAQ 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 689 LESLEKEN---------SQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKglelMKASFKKTERlevsyq 759
Cdd:pfam00038 179 YEEIAAKNreeaeewyqSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKK----QKASLERQLA------ 248
|
250 260 270
....*....|....*....|....*....|....*..
gi 1378869096 760 glDTEnQRLQKALENSNKKIQQLESELQDL--EMENQ 794
Cdd:pfam00038 249 --ETE-ERYELQLADYQELISELEAELQETrqEMARQ 282
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
594-846 |
3.26e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 594 ESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKkiTNLKITCEKIEALEQENSELERENR 673
Cdd:COG3096 836 AELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLAD--ETLADRLEELREELDAAQEAQAFIQ 913
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 674 KYKKTL-------DSFKNLTFQLESLEKENSQLDEENLELRRNVESLK--------CASMKMAQLQLENKELEsekEQLK 738
Cdd:COG3096 914 QHGKALaqleplvAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSevvqrrphFSYEDAVGLLGENSDLN---EKLR 990
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 739 KGLELMKASFKKT-ERLEVSYQGLDTENQRLQK---ALENSNKKIQQLESELQDL------EMENQTLQKNLE---ELKI 805
Cdd:COG3096 991 ARLEQAEEARREArEQLRQAQAQYSQYNQVLASlksSRDAKQQTLQELEQELEELgvqadaEAEERARIRRDElheELSQ 1070
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1378869096 806 SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1071 NRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
420-677 |
3.56e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.52 E-value: 3.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 420 KQSMDESLHLGWELEQISRTSElsEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEGTTSKILKIEKE 499
Cdd:pfam09731 167 KEASDTAEISREKATDSALQKA--EALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 500 NQRLSKKVEILENEIIQEKQSLQN--CQNLSKDLMKEKAQLEKTIETLRENserqikiLEQENEHLnqtvsslrQRSQIS 577
Cdd:pfam09731 245 VDQYKELVASERIVFQQELVSIFPdiIPVLKEDNLLSNDDLNSLIAHAHRE-------IDQLSKKL--------AELKKR 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 578 AEARVKD-IEKENKILHESIKETSSKLS-KIEFEKRQIRKELEH--------YKEKGERAEELENELH------------ 635
Cdd:pfam09731 310 EEKHIERaLEKQKEELDKLAEELSARLEeVRAADEAQLRLEFERereeiresYEEKLRTELERQAEAHeehlkdvlveqe 389
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1378869096 636 -------------HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKK 677
Cdd:pfam09731 390 ielqreflqdikeKVEEERAGRLLKLNELLANLKGLEKATSSHSEVEDENRKAQQ 444
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
394-644 |
3.83e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 45.69 E-value: 3.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 394 MEMERD----MDRKK---IEELMEENMtLEMAQKQSMDESLHLGWELEQISRTSELSEapqkSLGHEVNELTSSRLLKLE 466
Cdd:PRK05771 4 VRMKKVlivtLKSYKdevLEALHELGV-VHIEDLKEELSNERLRKLRSLLTKLSEALD----KLRSYLPKLNPLREEKKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 467 MENQSLtktvEELRSTMDSaegttsKILKIEKENQRLSKKVEILENEI---IQEKQSLQNCQNLSKDLmkEKAQLEKTIE 543
Cdd:PRK05771 79 VSVKSL----EELIKDVEE------ELEKIEKEIKELEEEISELENEIkelEQEIERLEPWGNFDLDL--SLLLGFKYVS 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 544 ----TLRENSERQIKILEQENEHLnqTVSSLRQRSQISAEARVKDIEKENKILH----------------ESIKETSSKL 603
Cdd:PRK05771 147 vfvgTVPEDKLEELKLESDVENVE--YISTDKGYVYVVVVVLKELSDEVEEELKklgferleleeegtpsELIREIKEEL 224
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1378869096 604 SKIEFEKRQIRKELEHYKEKGER-----AEELENELHHLEKENELL 644
Cdd:PRK05771 225 EEIEKERESLLEELKELAKKYLEellalYEYLEIELERAEALSKFL 270
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1134-1356 |
4.32e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 45.27 E-value: 4.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1134 LENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKG---- 1209
Cdd:pfam07888 50 QEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAahea 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1210 QLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGendrlnhtynqLLKETEvlqTDHKNLKSLLNSSRLEQTRLEAEFS 1289
Cdd:pfam07888 130 RIRELEEDIKTLTQRVLERETELERMKERAKKAGA-----------QRKEEE---AERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 1290 KLKEQYQQLDITSTKLNNQCELLSQlkgnleeenrhLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1356
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQ-----------KLTTAHRKEAENEALLEELRSLQERLNASER 251
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
4.81e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.39 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 305 ARMYRDELDALREKAVR--VDKLESEVSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRTSeLSEAPQ--------KSLGH 452
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARY-TPNHPDvialraqiAALRA 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 453 EVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEGTTSKILKIEKENQRLSKKVEILEN 512
Cdd:COG3206 306 QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
527-720 |
5.21e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 45.01 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 527 LSKDLMKEKAQLEKTIETLRENSERQIKILE-----------QENEHLNQTVSSLRQ-----RSQIS-AEARVKDIEKEN 589
Cdd:PHA02562 171 LNKDKIRELNQQIQTLDMKIDHIQQQIKTYNknieeqrkkngENIARKQNKYDELVEeaktiKAEIEeLTDELLNLVMDI 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 590 KILHESIKETSSKLSKIEFEKRQIRKELEHYKEKG-------------ERAEELENELHHLEKENELLQKKITNL-KITC 655
Cdd:PHA02562 251 EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGvcptctqqisegpDRITKIKDKLKELQHSLEKLDTAIDELeEIMD 330
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 656 EKIEA---LEQENSELERENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL--KCASMKM 720
Cdd:PHA02562 331 EFNEQskkLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIvkTKSELVK 400
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
5.78e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.75 E-value: 5.78e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1035-1113 |
6.05e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 42.61 E-value: 6.05e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1378869096 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
933-1238 |
6.29e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.51 E-value: 6.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 933 EKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEkIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:COG4372 6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEE-LEQLREELEQAREELEQLEEELEQARSELEQLEEELEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1013 EkmvqssppvsgednkwERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1092
Cdd:COG4372 85 L----------------NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAER 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1093 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQsSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASE 1172
Cdd:COG4372 149 EEELKELEEQLESLQEELAALEQELQALSEAEAEQALDE-LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1378869096 1173 YESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAE 1238
Cdd:COG4372 228 EAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAAL 293
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
247-408 |
6.52e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 6.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSAR------MYRDELDALREKAV 320
Cdd:COG4913 688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELralleeRFAAALGDAVEREL 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 321 RvDKLESEVSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDqLEGTRAR-----SDKLHELEKENLQLKAK--- 390
Cdd:COG4913 768 R-ENLEERIDALRARLNRAEeeLERAMRAFNREWPAETADLDADLES-LPEYLALldrleEDGLPEYEERFKELLNEnsi 845
|
170 180
....*....|....*....|....
gi 1378869096 391 ------LHDMEMERDMDRKKIEEL 408
Cdd:COG4913 846 efvadlLSKLRRAIREIKERIDPL 869
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
495-605 |
6.78e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.38 E-value: 6.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 495 KIEKENQRLSKKVEILENE---IIQEKQSLQNCQnlsKDLMKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQT 566
Cdd:PRK12704 83 ELQKLEKRLLQKEENLDRKlelLEKREEELEKKE---KELEQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEIL 159
|
90 100 110
....*....|....*....|....*....|....*....
gi 1378869096 567 VSSLRQRSQISAEARVKDIEKEnkilhesIKETSSKLSK 605
Cdd:PRK12704 160 LEKVEEEARHEAAVLIKEIEEE-------AKEEADKKAK 191
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
579-750 |
7.47e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 7.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKItcekI 658
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE----Y 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 659 EALEQENSELERENRKYKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG1579 92 EALQKEIESLKRRISDLEDEI---LELMERIEELEEELAELEAELAELEAELEEKK------AELDEELAELEAELEELE 162
|
170
....*....|..
gi 1378869096 739 KGLELMKASFKK 750
Cdd:COG1579 163 AEREELAAKIPP 174
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1167-1374 |
7.57e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 7.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1167 ERQASEYEsliaKHGTLKSAHKNLEVEHKDLEDRY--NQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCG 1244
Cdd:COG1196 206 ERQAEKAE----RYRELKEELKELEAELLLLKLREleAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1245 ENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDitsTKLNNQCELLSQLKGNLEEENR 1324
Cdd:COG1196 282 ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE---EELEELEEELEEAEEELEEAEA 358
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1325 HLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEE 1374
Cdd:COG1196 359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
7.74e-04 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 44.05 E-value: 7.74e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1378869096 792 ENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
7.79e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.46 E-value: 7.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 1378869096 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
505-769 |
7.82e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.53 E-value: 7.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 505 KKVEIL-ENEIIqeKQSLQNCQNLSK---DLMKEKAQLEKtietLRENSERQIKI------LEQENEHLNQTVSSLRQRS 574
Cdd:PRK05771 7 KKVLIVtLKSYK--DEVLEALHELGVvhiEDLKEELSNER----LRKLRSLLTKLsealdkLRSYLPKLNPLREEKKKVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 575 QISAEARVKDIEKE-NKILhESIKETSSKLSKIEFEKRQIRKELehykekgeraEELENeLHHLEKENELLQKKiTNLKI 653
Cdd:PRK05771 81 VKSLEELIKDVEEElEKIE-KEIKELEEEISELENEIKELEQEI----------ERLEP-WGNFDLDLSLLLGF-KYVSV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 654 TCEKI--EALEQENSELERENRKYKKTLDSFKNLTF-----QLESLEKENSQLDEENLELrrnvESLKCASMKMAQLQLE 726
Cdd:PRK05771 148 FVGTVpeDKLEELKLESDVENVEYISTDKGYVYVVVvvlkeLSDEVEEELKKLGFERLEL----EEEGTPSELIREIKEE 223
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1378869096 727 NKELESEKEQLKKGLelmKASFKKTERLEVSYQG-LDTENQRLQ 769
Cdd:PRK05771 224 LEEIEKERESLLEEL---KELAKKYLEELLALYEyLEIELERAE 264
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
342-984 |
7.93e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.43 E-value: 7.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 342 YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELeKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Cdd:pfam10174 125 HERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKL-LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQ 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 422 SMDESLHLGwelEQISRTSELSEAPQKSLG-HEVNELTSSRLLKLEMENQSLTKTVEELRSTMD-SAEGTTSKILKIE-- 497
Cdd:pfam10174 204 KEKENIHLR---EELHRRNQLQPDPAKTKAlQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLlHTEDREEEIKQMEvy 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 498 KENQRLSK-KVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENserqIKILEQENEHLNQTVSSLRQRsqi 576
Cdd:pfam10174 281 KSHSKFMKnKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKES----LTAKEQRAAILQTEVDALRLR--- 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 577 sAEARVKDIEKENKILHESIKETSS--------------KLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENE 642
Cdd:pfam10174 354 -LEEKESFLNKKTKQLQDLTEEKSTlageirdlkdmldvKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSS 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 643 LLQKKITNLK-ITCEKIEALEQENSELERENRKYKKTLDSF----KNLTFQLESLEKENSQLDEENLELRRNVESLKCAS 717
Cdd:pfam10174 433 NTDTALTTLEeALSEKERIIERLKEQREREDRERLEELESLkkenKDLKEKVSALQPELTEKESSLIDLKEHASSLASSG 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 718 MKMAQlqlENKELESEKEQLKKGLELMKASFKKTERLEVSyqgldtenqrlQKALENSNKKIQQLESELQDLEMENQTLQ 797
Cdd:pfam10174 513 LKKDS---KLKSLEIAVEQKKEECSKLENQLKKAHNAEEA-----------VRTNPEINDRIRLLEQEVARYKEESGKAQ 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 798 KNLEELkisskrLEQLEkenkslEQETSQLEKDKKQLEKENKRLRQqaeIKDTTLEENNVKIGNLEKENKtlfkeigiyk 877
Cdd:pfam10174 579 AEVERL------LGILR------EVENEKNDKDKKIAELESLTLRQ---MKEQNKKVANIKHGQQEMKKK---------- 633
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 878 esciRLKELEKENKELVKRATidiktlvtlredlVSEKLKTQQMNNDLEKLTHELEKIGLnkeRLLHDEQSTDDRYKLLE 957
Cdd:pfam10174 634 ----GAQLLEEARRREDNLAD-------------NSQQLQLEELMGALEKTRQELDATKA---RLSSTQQSLAEKDGHLT 693
|
650 660
....*....|....*....|....*..
gi 1378869096 958 SKLESTLKKSLEIKEEKIAALEARLEE 984
Cdd:pfam10174 694 NLRAERRKQLEEILEMKQEALLAAISE 720
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
924-1169 |
8.40e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 44.66 E-value: 8.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 924 DLEKLTHELEKIGLNKE--------------RLLHDEQSTDDRYKLLES------KLESTLKKSLEIKEEKIAALEARLE 983
Cdd:PRK10929 24 DEKQITQELEQAKAAKTpaqaeivealqsalNWLEERKGSLERAKQYQQvidnfpKLSAELRQQLNNERDEPRSVPPNMS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 984 eSTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSPpvsgedNKWERESQETTRELLKVKDRL--------IEVERNNA 1055
Cdd:PRK10929 104 -TDALEQEILQVSSQLLEKSRQAQQEQDRAREISDSL------SQLPQQQTEARRQLNEIERRLqtlgtpntPLAQAQLT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1056 TLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqtqNAKLQVENSTLNSQStslmNQNAQLLI 1129
Cdd:PRK10929 177 ALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL---DAYLQALRNQLNSQR----QREAERAL 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1378869096 1130 QQSSLENEN-----ESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Cdd:PRK10929 244 ESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
252-659 |
8.51e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.63 E-value: 8.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsarmyrdeldaLREKAVRVDKLESEVSR 331
Cdd:TIGR04523 322 KLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE--------------------LEEKQNEIEKLKKENQS 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 332 YKERLHDIEFYKARVEElkednqvlletktmledqlegtrarsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR04523 382 YKQEIKNLESQINDLES---------------------------KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNEltssrllklemENQSLTKTVEELRStmdsaegTTS 491
Cdd:TIGR04523 435 IIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK-----------IKQNLEQKQKELKS-------KEK 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 492 KILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQikILEQENEHLNQTVSSLR 571
Cdd:TIGR04523 497 ELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE--NLEKEIDEKNKEIEELK 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 572 QrsqisaearvkdiekENKILHESIKETSSKLSKIEFEKRQIRKELEhykEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:TIGR04523 575 Q---------------TQKSLKKKQEEKQELIDQKEKEKKDLIKEIE---EKEKKISSLEKELEKAKKENEKLSSIIKNI 636
|
....*...
gi 1378869096 652 KITCEKIE 659
Cdd:TIGR04523 637 KSKKNKLK 644
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1037-1352 |
8.75e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 43.90 E-value: 8.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1037 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqnnnLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTlnsQ 1116
Cdd:pfam15742 33 EKELRYERGKNLDLKQHNSLLQEENIKIKAELKQ-------AQQKLLDSTKMCSSLTAEWKHCQQKIRELELEVLK---Q 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1117 STSLMNQNA---QLLIQQSSLENENESVIKEREDLKS-----LYDSLIKDHEKLElLHERQASEYESliakhgTLKSAHK 1188
Cdd:pfam15742 103 AQSIKSQNSlqeKLAQEKSRVADAEEKILELQQKLEHahkvcLTDTCILEKKQLE-ERIKEASENEA------KLKQQYQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1189 NLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHET---VAAEYKKLCGENDRLNHTYNQ----LLKETE 1261
Cdd:pfam15742 176 EEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSQQQLRIQQQEAqlkQLENEKRKSDEHLKSNQELSEklssLQQEKE 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1262 VLQTDHKNLKSLLNSSRL----EQTRLEAEFSKLKEQY----QQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTL 1333
Cdd:pfam15742 256 ALQEELQQVLKQLDVHVRkyneKHHHHKAKLRRAKDRLvhevEQRDERIKQLENEIGILQQQSEKEKAFQKQVTAQNEIL 335
|
330
....*....|....*....
gi 1378869096 1334 MLQNRTLLEQNMESKDLFH 1352
Cdd:pfam15742 336 LLEKRKLLEQLTEQEELIK 354
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
796-1296 |
8.94e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 8.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEnkrLRQQAEIKDTTlEENNVKIGNLEKEnktlFKEIgi 875
Cdd:pfam01576 7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQ---LQAETELCAEA-EEMRARLAARKQE----LEEI-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 876 ykescirLKELEKENKELVKRATIdiktlvtlredLVSEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDRYKL 955
Cdd:pfam01576 77 -------LHELESRLEEEEERSQQ-----------LQNEKKKMQQHIQDLEEQLDEEEAA---RQKLQLEKVTTEAKIKK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 956 LESKL------ESTLKKSLEIKEEKIAALEARLEEStnynQQLRQELKTVKKNYEAL------------KQRQDEEKMVQ 1017
Cdd:pfam01576 136 LEEDIllledqNSKLSKERKLLEERISEFTSNLAEE----EEKAKSLSKLKNKHEAMisdleerlkkeeKGRQELEKAKR 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1018 ssppvsgednKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNT 1097
Cdd:pfam01576 212 ----------KLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLE 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1098 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLL---IQQSSLENENEsviKEREDLKSLYDSLIKDHE-KLELLHERQASEY 1173
Cdd:pfam01576 282 SERAARNKAEKQRRDLGEELEALKTELEDTLdttAAQQELRSKRE---QEVTELKKALEEETRSHEaQLQEMRQKHTQAL 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1174 ESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKgqledleKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNhty 1253
Cdd:pfam01576 359 EELTEQLEQAKRNKANLEKAKQALESENAELQAEL-------RTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR--- 428
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 1378869096 1254 NQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQ 1296
Cdd:pfam01576 429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQ 471
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
242-844 |
9.40e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.43 E-value: 9.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 242 RTESRQHLsVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMnllsdarsarmyrdeldALREKAVR 321
Cdd:pfam10174 156 RDESIKKL-LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENI-----------------HLREELHR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 322 VDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLE-GTRARSDKLHELEKENLQLKAKLHDMEMERDM 400
Cdd:pfam10174 218 RNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLlHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQE 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 401 DRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS----RTSEL-SEAPQKSLGHEVNELT----SSRLLKLEMENQS 471
Cdd:pfam10174 298 LSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTakeqRAAILqTEVDALRLRLEEKESFlnkkTKQLQDLTEEKST 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 472 LTKTVEELRSTMDSAEgttSKILKIEKENQRLSKKVEILENEIIQEKQSLQNCQNLSKD-------LMKEKAQLEKTIET 544
Cdd:pfam10174 378 LAGEIRDLKDMLDVKE---RKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNtdtalttLEEALSEKERIIER 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 545 LRENSER-------QIKILEQENEHLNQTVSSLrQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQ----- 612
Cdd:pfam10174 455 LKEQRERedrerleELESLKKENKDLKEKVSAL-QPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQkkeec 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 613 IRKELEHYK----EKGERA-EELENELHHLEKENELLQKKITNLKITCEKI-EALEQENSElerENRKYKKTLDSFKNLT 686
Cdd:pfam10174 534 SKLENQLKKahnaEEAVRTnPEINDRIRLLEQEVARYKEESGKAQAEVERLlGILREVENE---KNDKDKKIAELESLTL 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 687 FQLESLEKENSQL-DEENLELRRNVESLkcasmkmaQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTEN 765
Cdd:pfam10174 611 RQMKEQNKKVANIkHGQQEMKKKGAQLL--------EEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQ 682
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 766 QRLQKALENSNKKIQQLESELQD-LEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEnkrLRQQ 844
Cdd:pfam10174 683 QSLAEKDGHLTNLRAERRKQLEEiLEMKQEALLAAISEKDANIALLELSSSKKKKTQEEVMALKREKDRLVHQ---LKQQ 759
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
594-770 |
9.64e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 44.25 E-value: 9.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 594 ESIKETSSKLSKIEFEKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENR 673
Cdd:pfam05667 311 EAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVE---EELEELKEQNEELEKQYK 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 674 KYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA-SMKMAQL--QLENKELESEK--EQLKKGLELMKASF 748
Cdd:pfam05667 388 VKKKTLDLLPDAEENIAKLQALVDASAQRLVELAGQWEKHRVPlIEEYRALkeAKSNKEDESQRklEEIKELREKIKEVA 467
|
170 180
....*....|....*....|..
gi 1378869096 749 KKTERLEVSYQGLDTENQRLQK 770
Cdd:pfam05667 468 EEAKQKEELYKQLVAEYERLPK 489
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
761-916 |
1.11e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 44.28 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 761 LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE--- 837
Cdd:pfam05911 672 VSGSNDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkc 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 838 ----NKRLRQQAEIKDTTLEENNVKIGNLEKEnktLFKEIGIYKESCIRLKELE-----KENKELVKRATIDIKTLVTLR 908
Cdd:pfam05911 749 maesYEDLETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQeqlerNEKKESSNCDADQEDKKLQQE 825
|
170
....*....|
gi 1378869096 909 EDLV--SEKL 916
Cdd:pfam05911 826 KEITaaSEKL 835
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
972-1336 |
1.14e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 972 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKmvqssppvsGEDNKWERESQETTRELLKVKDRLIEVE 1051
Cdd:pfam01576 74 EEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEE---------AARQKLQLEKVTTEAKIKKLEEDILLLE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1052 RNNATLQAEKQALKTQLKQLETQ--------------NNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 1117
Cdd:pfam01576 145 DQNSKLSKERKLLEERISEFTSNlaeeeekakslsklKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1118 TSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLellhERQASEYESLIAKHgtlKSAHKNLEVEHKDL 1197
Cdd:pfam01576 225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIREL----EAQISELQEDLESE---RAARNKAEKQRRDL 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1198 EDRYNQLlkqKGQLEDLEKTLKVEQEkmlLKNKnHETVAAEYKKlCGENDRLNHtynqllkETEVLQTDHKNLKSLLN-S 1276
Cdd:pfam01576 298 GEELEAL---KTELEDTLDTTAAQQE---LRSK-REQEVTELKK-ALEEETRSH-------EAQLQEMRQKHTQALEElT 362
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 1277 SRLEQT-RLEAEFSKLKeqyQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQ 1336
Cdd:pfam01576 363 EQLEQAkRNKANLEKAK---QALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR 420
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
819-1379 |
1.20e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.96 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENnvkignLEKENKTLfkeigiyKESCIRLKELEKenkelvkrat 898
Cdd:pfam05557 6 ESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQ------LDRESDRN-------QELQKRIRLLEK---------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 899 idiktlvtlREDLVSEKLKTQ-QMNNDLEKLTHELEKIGLNKERLLHDEqstddryklleSKLESTLKKSLEIKEEKIAA 977
Cdd:pfam05557 63 ---------REAEAEEALREQaELNRLKKKYLEALNKKLNEKESQLADA-----------REVISCLKNELSELRRQIQR 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 978 LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKMVQSSPPVSGEDNK---WERESQETTRELLK-VKDRLIEVern 1053
Cdd:pfam05557 123 AELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKeleFEIQSQEQDSEIVKnSKSELARI--- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1054 nATLQAEKQALKTQLKQLETQNNNlqaqILALQRQTVSLQ---EQNTTLQTQNAKLQVENSTLNSQSTSLMNqnaqlLIQ 1130
Cdd:pfam05557 200 -PELEKELERLREHNKHLNENIEN----KLLLKEEVEDLKrklEREEKYREEAATLELEKEKLEQELQSWVK-----LAQ 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1131 QSSLEnenesvIKEREDLKSlydslikdheKLELLHERQASeyesLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQkgq 1210
Cdd:pfam05557 270 DTGLN------LRSPEDLSR----------RIEQLQQREIV----LKEENSSLTSSARQLEKARRELEQELAQYLKK--- 326
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1211 LEDLEKTLKVE-------QEKMLLKNKNHETVAAEYKKLCGENDRLNHTyNQLLKETEVLQTDHKNLKSLLNSSRLEQTR 1283
Cdd:pfam05557 327 IEDLNKKLKRHkalvrrlQRRVLLLTKERDGYRAILESYDKELTMSNYS-PQLLERIEEAEDMTQKMQAHNEEMEAQLSV 405
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1284 LEAEFSKLKEQYQQLDITSTKLNNQCELLSQlkGNLEEENRHLLDQIQTLMLQNRtlleqnmeskdlfhveqrqyidkln 1363
Cdd:pfam05557 406 AEEELGGYKQQAQTLERELQALRQQESLADP--SYSKEEVDSLRRKLETLELERQ------------------------- 458
|
570
....*....|....*.
gi 1378869096 1364 ELRRQKEKLEEKIMDQ 1379
Cdd:pfam05557 459 RLREQKNELEMELERR 474
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
722-1023 |
1.25e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 722 QLQLENKELESEKEQLKKGLELMKA----SFKKTERLEVSYQGLDTE--------------NQRLQKALENSNKKIQQLE 783
Cdd:COG3206 102 KLNLDEDPLGEEASREAAIERLRKNltvePVKGSNVIEISYTSPDPElaaavanalaeaylEQNLELRREEARKALEFLE 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 784 SELQDLEMENQTLQKNLEELKiSSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLe 863
Cdd:COG3206 182 EQLPELRKELEEAEAALEEFR-QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL- 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 864 kenktlfKEIGIYKESCIRLKELEKENKELVKRATIDIKTLVTLRedlvseklktQQMNNDLEKLTHELEKIglnkerll 943
Cdd:COG3206 260 -------LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALR----------AQIAALRAQLQQEAQRI-------- 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 944 hdEQSTDDRYKLLESKLESTlkksleikEEKIAALEARLEEStnynQQLRQELKTV-------KKNYEALKQRQDEEKMV 1016
Cdd:COG3206 315 --LASLEAELEALQAREASL--------QAQLAQLEARLAEL----PELEAELRRLerevevaRELYESLLQRLEEARLA 380
|
....*..
gi 1378869096 1017 QSSPPVS 1023
Cdd:COG3206 381 EALTVGN 387
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
1025-1462 |
1.31e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 43.91 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1025 EDNKWERESQETTRELLKVKDRLieveRNNATLQAEKQALKTQLKQLETQNNNLQAQILA----LQRQTVSLQEQNTT-- 1098
Cdd:COG5022 820 IKLQKTIKREKKLRETEEVEFSL----KAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQrvelAERQLQELKIDVKSis 895
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1099 -LQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLE---NENESVIKEREDLKSLYDSLIKDHEKLELLHErQASEYE 1174
Cdd:COG5022 896 sLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLkklLNNIDLEEGPSIEYVKLPELNKLHEVESKLKE-TSEEYE 974
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1175 SLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGEND----RLN 1250
Cdd:COG5022 975 DLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPlqklKGL 1054
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1251 HT--YNQLLKETEVLQTDHKNLKSL-LNSSRLEQTR---LEAEFSKLKEQYQQLDITSTKLNNQceLLSQLKGNLEEENR 1324
Cdd:COG5022 1055 LLleNNQLQARYKALKLRRENSLLDdKQLYQLESTEnllKTINVKDLEVTNRNLVKPANVLQFI--VAQMIKLNLLQEIS 1132
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1325 HLLDQ-IQTLMLQNRTLLEQNMESKDLFHV---EQRQYIDKLNELrRQKEKLEEKIMDQYKFYDPS------------PP 1388
Cdd:COG5022 1133 KFLSQlVNTLEPVFQKLSVLQLELDGLFWEanlEALPSPPPFAAL-SEKRLYQSALYDEKSKLSSSevndlknelialFS 1211
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1389 RRRGNWIT-LKMRKLIKS-------KKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQDSSS---------------VG 1445
Cdd:COG5022 1212 KIFSGWPRgDKLKKLISEgwvpteySTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSykleeevlpatinslLQ 1291
|
490
....*....|....*..
gi 1378869096 1446 SNSLEDGQTLGTKKSSM 1462
Cdd:COG5022 1292 YINVGLFNALRTKASSL 1308
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
683-969 |
1.37e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 42.98 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 683 KNLTFQLESLEKENSQLDEENLELRRNVESL-KCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTerlevsyqgl 761
Cdd:COG1340 4 DELSSSLEELEEKIEELREEIEELKEKRDELnEELKELAEKRDELNAQVKELREEAQELREKRDELNEKV---------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 762 dtenQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKenkslEQETSQLEKDK-KQLEKENKR 840
Cdd:COG1340 74 ----KELKEERDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEW-----RQQTEVLSPEEeKELVEKIKE 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 841 LRQQAEIKDTTLEENN-------------VKIGNLEKENKTLFKEIGIYKEScirLKELEKENKELVKRATIDIKTLVTL 907
Cdd:COG1340 145 LEKELEKAKKALEKNEklkelraelkelrKEAEEIHKKIKELAEEAQELHEE---MIELYKEADELRKEADELHKEIVEA 221
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 908 REDLVSEKLKTQQMNNDLEKLTHELEKI--GLNKERLLHDEQSTDDRYKLLESKLESTLKKSLE 969
Cdd:COG1340 222 QEKADELHEEIIELQKELRELRKELKKLrkKQRALKREKEKEELEEKAEEIFEKLKKGEKLTTE 285
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
939-1376 |
1.46e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 939 KERLLHDEQSTDDRYKLLESKlestlkKSLEIKEEKIAALEARLEESTNYNQQLRQElktvkknYEALKQRQD--EEKMV 1016
Cdd:PRK04863 279 NERRVHLEEALELRRELYTSR------RQLAAEQYRLVEMARELAELNEAESDLEQD-------YQAASDHLNlvQTALR 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1017 QSsppvsgedNKWERESQEttreLLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQiLALQRQTVSLQeQN 1096
Cdd:PRK04863 346 QQ--------EKIERYQAD----LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQ-LADYQQALDVQ-QT 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1097 TTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQssLENENESVIKEREDLK---SLYDSLIKDHEKLELLHERQASEY 1173
Cdd:PRK04863 412 RAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEE--FQAKEQEATEELLSLEqklSVAQAAHSQFEQAYQLVRKIAGEV 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1174 ESLIAKHgTLKSAHKNLEvEHKDLEDRYNQLlkqKGQLEDLEKTLKVEQekmllknkNHETVAAEYKKLCGENDRLNHTY 1253
Cdd:PRK04863 490 SRSEAWD-VARELLRRLR-EQRHLAEQLQQL---RMRLSELEQRLRQQQ--------RAERLLAEFCKRLGKNLDDEDEL 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1254 NQLLKETEVLQTDHKNLKSllnSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK---GNLEEENRHLLDQI 1330
Cdd:PRK04863 557 EQLQEELEARLESLSESVS---EARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLReqsGEEFEDSQDVTEYM 633
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1378869096 1331 QTLMLQNRTLLEQNmeskdlfhveqrqyidklNELRRQKEKLEEKI 1376
Cdd:PRK04863 634 QQLLERERELTVER------------------DELAARKQALDEEI 661
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
257-550 |
1.49e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 43.69 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 257 KAKIRRLRQELEEKTEQLLDCKQE--------LEQMeieLKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEse 328
Cdd:PLN03229 428 KTPVRELEGEVEKLKEQILKAKESsskpselaLNEM---IEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKANSQD-- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 329 vsrykERLHDIefYKARVEELKEDNQVLLETK---TMLEDQLEGTRA--RSDKLHELEKENLQLKAKLHDM---EMERDM 400
Cdd:PLN03229 503 -----QLMHPV--LMEKIEKLKDEFNKRLSRApnyLSLKYKLDMLNEfsRAKALSEKKSKAEKLKAEINKKfkeVMDRPE 575
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 401 DRKKIEELMEENMTLEMAQKQSMDESLhlgweLEQISRTSELSEAPQ----KSLGHEVNELTSSRLL------------K 464
Cdd:PLN03229 576 IKEKMEALKAEVASSGASSGDELDDDL-----KEKVEKMKKEIELELagvlKSMGLEVIGVTKKNKDtaeqtpppnlqeK 650
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 465 LEMENQSLTKTVEELrstMDSAE-GTTSKILKIE------KENQRLSKKVEILENEIiqeKQSLQNCQNLSKdlMKEK-A 536
Cdd:PLN03229 651 IESLNEEINKKIERV---IRSSDlKSKIELLKLEvakaskTPDVTEKEKIEALEQQI---KQKIAEALNSSE--LKEKfE 722
|
330
....*....|....
gi 1378869096 537 QLEKTIETLRENSE 550
Cdd:PLN03229 723 ELEAELAAARETAA 736
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
697-868 |
1.53e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 43.66 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 697 SQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQgldteNQRLQKALENSN 776
Cdd:PRK00409 509 KLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEA-----EKEAQQAIKEAK 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 777 KKIQQLESELQDLEMENQTLQKnleeLKISSKRLEQLEKENKSLEQETSQLEKDKKQLeKENKRLR-----QQAEI---- 847
Cdd:PRK00409 584 KEADEIIKELRQLQKGGYASVK----AHELIEARKRLNKANEKKEKKKKKQKEKQEEL-KVGDEVKylslgQKGEVlsip 658
|
170 180
....*....|....*....|....*..
gi 1378869096 848 --KDTTLEEN----NVKIGNLEKENKT 868
Cdd:PRK00409 659 ddKEAIVQAGimkmKVPLSDLEKIQKP 685
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1207-1375 |
1.57e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1207 QKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEA 1286
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1287 EFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELR 1366
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
....*....
gi 1378869096 1367 RQKEKLEEK 1375
Cdd:COG4942 178 ALLAELEEE 186
|
|
| S6OS1 |
pfam15676 |
Six6 opposite strand transcript 1 family; This family of proteins is found in eukaryotes. ... |
610-844 |
1.59e-03 |
|
Six6 opposite strand transcript 1 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 114 and 587 amino acids in length. The function is not known.
Pssm-ID: 464795 Cd Length: 557 Bit Score: 43.29 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 610 KRQIRKELEHYKEKGERAEEL-------ENELHHLEKENELLQKKITNLKITCEKIEALE----------QENSELEREN 672
Cdd:pfam15676 1 NQQINLCSEKIKEKKKEIAKLheninksDEEIAHYRKHNENIKDSCINWKPTYDVLHKHEdylqnqfqvyQETTEKDKKM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 673 -----RKYKKTLDSFKnLTFQLESLEKENSQLDEENLELRRNVesLKCASmkmaQLQLenkeleseKEQLKKGLeLMKAS 747
Cdd:pfam15676 81 yhdyiSQYKDVLKQYQ-LKYSETPLAQEYYKKKKEVEEIQNRI--LACSE----QLKL--------KETILMEL-LVPAP 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 748 FKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ----E 823
Cdd:pfam15676 145 FKSLPDWALYIVNLRYKTEDILKLANTFTQKSSELKKEADEMEMKINYLNKQFERLSEDKNLSEMLEEKNKSLEKrkefK 224
|
250 260
....*....|....*....|.
gi 1378869096 824 TSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam15676 225 ERIFEEDEHPLVLEEYQQNSQ 245
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
260-525 |
1.62e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 42.88 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLsdARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDI 339
Cdd:pfam15905 82 IRALVQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLS--ASVASLEKQLLELTRVNELLKAKFSEDGTQKKMSSLSM 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 340 EFYKARvEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQ 419
Cdd:pfam15905 160 ELMKLR-NKLEAKMKEVMAKQEGMEGKLQVTQ---KNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVS 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 420 KQsmdeslhlgweLEQISRTSELSEAPQKSLGHEVNELTSSrllkLEMENQSLTKTVEELRSTMDSAEGTTSKILKIEKE 499
Cdd:pfam15905 236 EQ-----------VEKYKLDIAQLEELLKEKNDEIESLKQS----LEEKEQELSKQIKDLNEKCKLLESEKEELLREYEE 300
|
250 260
....*....|....*....|....*..
gi 1378869096 500 -NQRLSKKVEILENEIIQEKQSLQNCQ 525
Cdd:pfam15905 301 kEQTLNAELEELKEKLTLEEQEHQKLQ 327
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
567-869 |
1.66e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 43.69 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 567 VSSLRQRSQISAEAR---VKDIEKENKILHESI---KETSSKLSK------IEFEKRQIRKEL-EHYKEKG--ERAEELE 631
Cdd:PLN03229 413 VDPERKVNMKKREAVktpVRELEGEVEKLKEQIlkaKESSSKPSElalnemIEKLKKEIDLEYtEAVIAMGlqERLENLR 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 632 NELHHLEKENELLQKkitNLKitcEKIEALEQE-NSELER----ENRKYK-KTLDSFKNLTFQLE------SLEKE-NSQ 698
Cdd:PLN03229 493 EEFSKANSQDQLMHP---VLM---EKIEKLKDEfNKRLSRapnyLSLKYKlDMLNEFSRAKALSEkkskaeKLKAEiNKK 566
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 699 LDE--ENLELRRNVESLK--CASMKMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVS-------YQGLDTENQR 767
Cdd:PLN03229 567 FKEvmDRPEIKEKMEALKaeVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLKSMGLEVIgvtkknkDTAEQTPPPN 646
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 768 LQKALENSNKKI-QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE----------TSQLEKDKKQLEK 836
Cdd:PLN03229 647 LQEKIESLNEEInKKIERVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQikqkiaealnSSELKEKFEELEA 726
|
330 340 350
....*....|....*....|....*....|...
gi 1378869096 837 ENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL 869
Cdd:PLN03229 727 ELAAARETAAESNGSLKNDDDKEEDSKEDGSRV 759
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-668 |
1.74e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 320 VRVDKLEsevsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 480 RSTMDSAEGTTSKILKIEK----ENQR-LSKKVEILENEIIQEKQSLQNCQNLSKdLMKEKAQLEKTIETLRENSERQIK 554
Cdd:PRK04863 483 RKIAGEVSRSEAWDVARELlrrlREQRhLAEQLQQLRMRLSELEQRLRQQQRAER-LLAEFCKRLGKNLDDEDELEQLQE 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 555 ILEQENEHLNQTVSSLRQRSqisaeARVKDIEKENKILHEsiketssKLSKIEFEKRQIRKEL----EHYKEKGERAEEL 630
Cdd:PRK04863 562 ELEARLESLSESVSEARERR-----MALRQQLEQLQARIQ-------RLAARAPAWLAAQDALarlrEQSGEEFEDSQDV 629
|
410 420 430
....*....|....*....|....*....|....*....
gi 1378869096 631 ENEL-HHLEKENELLQKKITnlkiTCEKIEALEQENSEL 668
Cdd:PRK04863 630 TEYMqQLLERERELTVERDE----LAARKQALDEEIERL 664
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
705-1114 |
1.86e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 43.20 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 705 ELRRNVESLKcaSMKMAQLQlENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLES 784
Cdd:pfam07111 74 ELRRLEEEVR--LLRETSLQ-QKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQRELEEIQRLHQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 785 ElqDLEMENQTLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEk 864
Cdd:pfam07111 151 E--QLSSLTQAHEEALSSL---TSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLR- 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 865 enktlfKEIGIYKESCIRLKELEKENKELvkratidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELekiGLNKERLLH 944
Cdd:pfam07111 225 ------KYVGEQVPPEVHSQTWELERQEL-------LDTMQHLQEDRADLQATVELLQVRVQSLTHML---ALQEEELTR 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 945 DEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKknyealkqrqdEEKMVQSsppvsg 1024
Cdd:pfam07111 289 KIQPSDSLEPEFPKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAELQ-----------EQVTSQS------ 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1025 ednkwerESQETTRELLKVKDRLIEVERNNA-TLQAE----KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTL 1099
Cdd:pfam07111 352 -------QEQAILQRALQDKAAEVEVERMSAkGLQMElsraQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRV 424
|
410
....*....|....*
gi 1378869096 1100 QTQNAKLQVENSTLN 1114
Cdd:pfam07111 425 EQAVARIPSLSNRLS 439
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
652-895 |
1.92e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.08 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 652 KITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESLEKENsqLDEENLELRRNVESLKCASMKMAQLQLENKELE 731
Cdd:PHA02562 170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGEN--IARKQNKYDELVEEAKTIKAEIEELTDELLNLV 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 732 SEKEQLKkglelmkASFKKterlevsyqgLDTENQRLQKALENSNKKIQQLESE------LQDLEMENQTLQKNLEELKI 805
Cdd:PHA02562 248 MDIEDPS-------AALNK----------LNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLKE 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 806 SSKRLEQLEKEnkslEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEIGIYKEScirLKE 885
Cdd:PHA02562 311 LQHSLEKLDTA----IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE---LAK 383
|
250
....*....|
gi 1378869096 886 LEKENKELVK 895
Cdd:PHA02562 384 LQDELDKIVK 393
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
375-1039 |
2.01e-03 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 43.24 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 375 DKLHELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Cdd:PTZ00341 414 DLLFDLEKQKyMDMLDGSEDESVEDNEEEHSGDANEEELSVDEHVEEHNADDSGEQQSDDESGEHQSVNEIVEEQSVNEH 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 454 VNELTSSRLLKLEMENQSLTKTV----EELRSTMDSAEGTTSKILKIEKENQRLSKKVEILENEIIQEKQ---SLQNCQN 526
Cdd:PTZ00341 494 VEEPTVADIVEQETVDEHVEEPAvdenEEQQTADEHVEEPTIAEEHVEEEISTAEEHIEEPASDVQQDSEaapTIEIPDT 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 527 LSKDLMKEKAQLEktietLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV-KDIEKE---NKILHESIKETS-- 600
Cdd:PTZ00341 574 LFYDILGVGVNAD-----MKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQIlGDIDKKkmyNKFGYDGIKGVNfi 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 601 --------SKLSKIEF--EKRQIRKELEHYKEKGERAEELENELHHLEKENELLQKKiTNLKITCEKIEALEQENSELER 670
Cdd:PTZ00341 649 hpsifyllASLEKFADftGSPQIVTLLKFFFEKKLSMNDLDNKSEHLLKFMEQYQKE-REAHISENLINILQPCIAGDRK 727
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 671 ENRKYKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVeslKCASMKMAQLQLENKE-LESEKEQLkkgLELMKASFK 749
Cdd:PTZ00341 728 WDVPIIDKIEELKGSPFDIAIIDSIGWIFKHVAKSHLKKP---KKAAKKLEQRSKANKEeLANENNKL---MNILKEYFG 801
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 750 KTERLE-----VSYQGLDTENQRLQKALENSNKKIQQ----------LESELQDLE-----MENQTLQKNLEELKISSKR 809
Cdd:PTZ00341 802 NNEQINsitynFENINLNEDNENGSKKILDLNHKDQKeifeeiisyiVDISLSDIEntaknAAEQILSDEGLDEKKLKKR 881
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 810 LEQLEKENKSLEQETSQLEKDKKQLEKE---------------NKRLRQQAEIKDTTLEEN-NVKIGNLEKENKTLFKEI 873
Cdd:PTZ00341 882 AESLKKLANAIEKYAGGGKKDKKAKKKDakdlsgniaheinliNKELKNQNENVPEHLKEHaEANIEEDAEENVEEDAEE 961
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 874 GIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDL-------VSEKLKTQQMNNDLEKLTHELEKIGLNKERllHDE 946
Cdd:PTZ00341 962 NVEENVEENVEENVEENVEENVEENVEENVEENVEENVeenieenVEENVEENIEENVEEYDEENVEEVEENVEE--YDE 1039
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 947 QSTDDRYKLLESKLESTLKKSLE-IKEEKIAALEARLEESTNYNQQlrqelKTVKKNYEALKQRQDE--EKMVQSSPPVS 1023
Cdd:PTZ00341 1040 ENVEEIEENAEENVEENIEENIEeYDEENVEEIEENIEENIEENVE-----ENVEENVEEIEENVEEnvEENAEENAEEN 1114
|
730
....*....|....*.
gi 1378869096 1024 GEDNKwERESQETTRE 1039
Cdd:PTZ00341 1115 AEENA-EEYDDENPEE 1129
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
719-889 |
2.03e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 41.43 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 719 KMAQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQG------------------LDTENQRLQKALENSNKKIQ 780
Cdd:pfam15619 12 KIKELQNELAELQSKLEELRKENRLLKRLQKRQEKALGKYEGteselpqliarhneevrvLRERLRRLQEKERDLERKLK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 781 QLESELQDLEMENQTLQ-----KNLEELKISSKRLEQLEKEnksLEQETSQLEKDKKQLEKENKRLRQQaeikdttLEEN 855
Cdd:pfam15619 92 EKEAELLRLRDQLKRLEklsedKNLAEREELQKKLEQLEAK---LEDKDEKIQDLERKLELENKSFRRQ-------LAAE 161
|
170 180 190
....*....|....*....|....*....|....
gi 1378869096 856 NVKIGNLEKENKTLFKEIGIYKEsciRLKELEKE 889
Cdd:pfam15619 162 KKKHKEAQEEVKILQEEIERLQQ---KLKEKERE 192
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
972-1298 |
2.09e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.42 E-value: 2.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 972 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKmvqssppvsgednKWERESQETTRELLKVKDRLIEVE 1051
Cdd:TIGR00618 193 HGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL-------------QQTQQSHAYLTQKREAQEEQLKKQ 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1052 RNNATLQAEKQALKTQLKQLETQNNNLQaqilaLQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQstslMNQNAQLLIQQ 1131
Cdd:TIGR00618 260 QLLKQLRARIEELRAQEAVLEETQERIN-----RARKAAPLAAHIKAVTQIEQQAQRIHTELQSK----MRSRAKLLMKR 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1132 SSLENENESVIKEREDLKSLYdsliKDHEKLELLHERQASEYESLIAKHgtlksahknlevehkDLEDRYNQLLKQKGQL 1211
Cdd:TIGR00618 331 AAHVKQQSSIEEQRRLLQTLH----SQEIHIRDAHEVATSIREISCQQH---------------TLTQHIHTLQQQKTTL 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1212 EDLEKTLKveQEKMLLKNKNHeTVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKL 1291
Cdd:TIGR00618 392 TQKLQSLC--KELDILQREQA-TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSL 468
|
....*..
gi 1378869096 1292 KEQYQQL 1298
Cdd:TIGR00618 469 KEREQQL 475
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1044-1113 |
2.09e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 39.09 E-value: 2.09e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1044 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Cdd:cd22887 3 ESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
592-707 |
2.28e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 42.41 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 592 LHESIKETSSKLSKIEFEKRQIRKELEhykEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERE 671
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENE---ELESELEELREEYKKLREENSILEEEFDNIK---SEYSDLKSRFEELLKK 206
|
90 100 110
....*....|....*....|....*....|....*...
gi 1378869096 672 NrkykktldSFKnlTFQLESLEKE--NSQLDEENLELR 707
Cdd:COG4026 207 R--------LLE--VFSLEELWKElfPEELPEEDFIYF 234
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1137-1374 |
2.47e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.00 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1137 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQkgqLEDLEK 1216
Cdd:COG1196 226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE---LARLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1217 TLKVEQEKmllknKNHETVAAEykklcgendrlnhtynQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQ 1296
Cdd:COG1196 303 DIARLEER-----RRELEERLE----------------ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 1297 QLDitstklnnqcELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLfhveQRQYIDKLNELRRQKEKLEE 1374
Cdd:COG1196 362 EAE----------EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL----EEAEEALLERLERLEEELEE 425
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1030-1359 |
2.56e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.58 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE 1109
Cdd:COG4372 44 QEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1110 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEyesliakhGTLKSAHKN 1189
Cdd:COG4372 124 RQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALD--------ELLKEANRN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1190 LEVEHKDLEDRYNQLLKQKGQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKN 1269
Cdd:COG4372 196 AEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEE 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1270 LKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1349
Cdd:COG4372 276 EELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDV 355
|
330
....*....|
gi 1378869096 1350 LFHVEQRQYI 1359
Cdd:COG4372 356 LELLSKGAEA 365
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1086-1432 |
2.56e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.18 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1086 QRQTVSLQEQNTTLQTQNAKLQVENSTLnsqsTSLMNQNAQlliQQSSLENENESVIKEREDLKSLYDSLIKDH------ 1159
Cdd:pfam15921 102 EKQKFYLRQSVIDLQTKLQEMQMERDAM----ADIRRRESQ---SQEDLRNQLQNTVHELEAAKCLKEDMLEDSntqieq 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1160 -EKLELLHERQASEYESLIAK----HGTLKSAHKNLEVEH-KDLEDRYNQLLKQ--------KGQL---EDLEKTLKVE- 1221
Cdd:pfam15921 175 lRKMMLSHEGVLQEIRSILVDfeeaSGKKIYEHDSMSTMHfRSLGSAISKILREldteisylKGRIfpvEDQLEALKSEs 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1222 QEKMLLKNKNHEtvaaeykklcgenDRLNhtynQLLKETEVLQTdhkNLKSLLNSSRLEQTRLEAEFSKLKEQYQ-QLDI 1300
Cdd:pfam15921 255 QNKIELLLQQHQ-------------DRIE----QLISEHEVEIT---GLTEKASSARSQANSIQSQLEIIQEQARnQNSM 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1301 TSTKLNNQCELLSQLKGNLEEENRHLLDQIQ----TLMLQNRTLLEQNMEsKDLFHVEQRQYIDKLNEL-----RRQKEK 1371
Cdd:pfam15921 315 YMRQLSDLESTVSQLRSELREAKRMYEDKIEelekQLVLANSELTEARTE-RDQFSQESGNLDDQLQKLladlhKREKEL 393
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 1372 LEEKIMDQyKFYDpsppRRRGNWITLKmrKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQ 1432
Cdd:pfam15921 394 SLEKEQNK-RLWD----RDTGNSITID--HLRRELDDRNMEVQRLEALLKAMKSECQGQME 447
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1031-1211 |
2.58e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1031 RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL--QV 1108
Cdd:COG1579 3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYeeQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1109 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIAKhgtLKSAHK 1188
Cdd:COG1579 83 GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE---LEAELE 159
|
170 180 190
....*....|....*....|....*....|.
gi 1378869096 1189 NLEVEHKDLE--------DRYNQLLKQKGQL 1211
Cdd:COG1579 160 ELEAEREELAakippellALYERIRKRKNGL 190
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
613-938 |
2.60e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.97 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 613 IRKELEHYKEKGERAEELENELhhLEKENELLQKKITNLKITCEKIEALEQENSELERENRKYKKtlDSFKNLTFQLESL 692
Cdd:PLN02939 58 QRSSNSKLQSNTDENGQLENTS--LRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK--DGEQLSDFQLEDL 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 693 ekensqldeenLELRRNVES--LKCASMKMAQLQLENKELeSEKEQLKKGLELMKASFKKT-ERLEVSYQG------LDT 763
Cdd:PLN02939 134 -----------VGMIQNAEKniLLLNQARLQALEDLEKIL-TEKEALQGKINILEMRLSETdARIKLAAQEkihveiLEE 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 764 ENQRLQKAL----ENSNKKIQQLESELQDLEMEN-------QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE---- 828
Cdd:PLN02939 202 QLEKLRNELlirgATEGLCVHSLSKELDVLKEENmllkddiQFLKAELIEVAETEERVFKLEKERSLLDASLRELEskfi 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 829 ---KDKKQL---------EK-EN-----KRLRQQAEIKDTTLEENNVKIGNLEKENKTLfKEIGIYKESCIRLKELEKEN 890
Cdd:PLN02939 282 vaqEDVSKLsplqydcwwEKvENlqdllDRATNQVEKAALVLDQNQDLRDKVDKLEASL-KEANVSKFSSYKVELLQQKL 360
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 891 K---ELVKRATIDIKTLVTLREDLVSEklktqqMNNDLEKLTHELEKIGLN 938
Cdd:PLN02939 361 KlleERLQASDHEIHSYIQLYQESIKE------FQDTLSKLKEESKKRSLE 405
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
776-1201 |
2.68e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 42.75 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 776 NKKIQQLESELQDLEMENQTLQKNLEELK-------ISSKRLEQLEKENKSLEQETSQLEKDKKQLekenkrlRQQAEIK 848
Cdd:pfam05622 20 DQQVSLLQEEKNSLQQENKKLQERLDQLEsgddsgtPGGKKYLLLQKQLEQLQEENFRLETARDDY-------RIKCEEL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 849 DTTLEENNVKIGNLEK---ENKTLFKEIGIYKESCIRLKELEkenkelvkrATIDiktlvtlredlvSEKLKTQQMNnDL 925
Cdd:pfam05622 93 EKEVLELQHRNEELTSlaeEAQALKDEMDILRESSDKVKKLE---------ATVE------------TYKKKLEDLG-DL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 926 EKLTHELEkiglnkERLLHDEQSTDDRYKllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 1005
Cdd:pfam05622 151 RRQVKLLE------ERNAEYMQRTLQLEE--ELKKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEA 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1006 LKQRQD-------------EE----KMVQSSPPVSGEDNKWERESQETT-RELL--KVKDRLIEVERNNATL-------- 1057
Cdd:pfam05622 223 LQKEKErliierdtlretnEElrcaQLQQAELSQADALLSPSSDPGDNLaAEIMpaEIREKLIRLQHENKMLrlgqegsy 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1058 ---QAEKQALKTQ----LKQLETQNNNLQAQILALQRQTVSLQeqnTTLQTQNAKlqvenstlnSQSTSLMNQNAQLLIQ 1130
Cdd:pfam05622 303 rerLTELQQLLEDanrrKNELETQNRLANQRILELQQQVEELQ---KALQEQGSK---------AEDSSLLKQKLEEHLE 370
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 1131 QsslenenesvikeredLKSLYDSLIKdheKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRY 1201
Cdd:pfam05622 371 K----------------LHEAQSELQK---KKEQIEELEPKQDSNLAQKIDELQEALRKKDEDMKAMEERY 422
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-682 |
3.01e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.70 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsdarsarmYRDELDALREKavrVDKLESEVSRYKERL 336
Cdd:TIGR04523 341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS----------YKQEIKNLESQ---INDLESKIQNQEKLN 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 337 HDIEfykARVEELKEDNQVLLETKTMLEDQLEgtrARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR04523 408 QQKD---EQIKKLQQEKELLEKEIERLKETII---KNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIK 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 417 MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTsSRLLKLEMENQSLTKTVEELRSTMDSAEgTTSKILKI 496
Cdd:TIGR04523 482 QNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK-EKIEKLESEKKEKESKISDLEDELNKDD-FELKKENL 559
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 497 EKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIE---TLRENSERQIKILEQENEHLNQTVSSLRQR 573
Cdd:TIGR04523 560 EKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEekeKKISSLEKELEKAKKENEKLSSIIKNIKSK 639
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 574 SQIsaearvkdIEKENKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKI 653
Cdd:TIGR04523 640 KNK--------LKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIEL---MKDWLKELSLHYKKYITRMIRIKDLPK 708
|
410 420
....*....|....*....|....*....
gi 1378869096 654 TCEKIEALEQENSELErenrKYKKTLDSF 682
Cdd:TIGR04523 709 LEEKYKEIEKELKKLD----EFSKELENI 733
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
786-916 |
3.22e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 41.64 E-value: 3.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 786 LQDLEMENQtLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIkdttLEENNVKIGNLEKE 865
Cdd:COG4026 124 LQNIPEYNE-LREELLELK---EKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSI----LEEEFDNIKSEYSD 195
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1378869096 866 NKTLFKEigIYKESCIRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Cdd:COG4026 196 LKSRFEE--LLKKRLLEVFSLEELWKELFPEELPEEDFIYFATENLKPGKI 244
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
490-636 |
3.29e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 490 TSKILKIEKENQRL----SKKVEILENEIIQEKQslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQ 565
Cdd:PRK12704 30 EAKIKEAEEEAKRIleeaKKEAEAIKKEALLEAK---------EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDR 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 566 TVSSLRQRsqisaEARVKDIEKENKILHESIKETSSKLSKIEFEKRQirkELEHY----KE--KGERAEELENELHH 636
Cdd:PRK12704 101 KLELLEKR-----EEELEKKEKELEQKQQELEKKEEELEELIEEQLQ---ELERIsgltAEeaKEILLEKVEEEARH 169
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
265-1015 |
3.38e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 42.90 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDE----LDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:PTZ00440 522 KNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDiknkIKYIEENVDHIKDIISLNDEIDNIIQQIE 601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 341 -------FYKARVEELKEDNQVLLETkTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEenm 413
Cdd:PTZ00440 602 elinealFNKEKFINEKNDLQEKVKY-ILNKFYKGDLQELLDELSHFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEK--- 677
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 414 tLEMAQKQSMDESLH-LGWELEQIsrtSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRSTMDSAEGTTSK 492
Cdd:PTZ00440 678 -LEFMKSDNIDNIIKnLKKELQNL---LSLKENIIKKQLNNIEQDISNSLNQYTIKYNDLKSSIEEYKEEEEKLEVYKHQ 753
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 493 ILKI-------EKENQRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQ 565
Cdd:PTZ00440 754 IINRknefilhLYENDKDLPDGKNTYEEFLQYKDTILNKENKISNDINILKENKKNNQDLLNSYNILIQKLEAHTEKNDE 833
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 566 TVSSLRQR-------------------SQISAEARVKDIEKEN------KILHESIKETSSKLSKIEF---EKRQIRKEL 617
Cdd:PTZ00440 834 ELKQLLQKfptedenlnlkelekefneNNQIVDNIIKDIENMNkniniiKTLNIAINRSNSNKQLVEHllnNKIDLKNKL 913
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 618 EHYKEKGER-----AEELENELHHLEKENELLQKKITNLKITCEKIEAleqenselERENRKYKKTLDSFK-NLTFQLES 691
Cdd:PTZ00440 914 EQHMKIINTdniiqKNEKLNLLNNLNKEKEKIEKQLSDTKINNLKMQI--------EKTLEYYDKSKENINgNDGTHLEK 985
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 692 LEKENSQLDEENLELRRNVESLKCASMKMAQLQLE----------------NKELESEKEQLKKGLELMKA---SFKKTE 752
Cdd:PTZ00440 986 LDKEKDEWEHFKSEIDKLNVNYNILNKKIDDLIKKqhddiielidklikekGKEIEEKVDQYISLLEKMKTklsSFHFNI 1065
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 753 RLEVSYQGLDTEN-QRLQKALENSNKKIQQLESELqdLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:PTZ00440 1066 DIKKYKNPKIKEEiKLLEEKVEALLKKIDENKNKL--IEIKNKSHEHVVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTL 1143
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 832 KQLEKENKRLRQQAEIKDTTLE-------ENNVKIGNLEKENKTLFKEIGIYKESCI----------------------- 881
Cdd:PTZ00440 1144 KELENMNLEDITLNEVNEIEIEyerilidHIVEQINNEAKKSKTIMEEIESYKKDIDqvkknmskerndhlttfeynayy 1223
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 882 -RLKELEKENKELVKRA---------TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEkiglNKERLLhdeQSTDD 951
Cdd:PTZ00440 1224 dKATASYENIEELTTEAkglkgeanrSTNVDELKEIKLQVFSYLQQVIKENNKMENALHEIK----NMYEFL---ISIDS 1296
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1378869096 952 RyKLLESKLESTlKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEEKM 1015
Cdd:PTZ00440 1297 E-KILKEILNST-KKAEEFSNDAKKELEKTDNLIKQVEAKIEQAKEHKNKIYGSLEDKQIDDEI 1358
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
243-345 |
3.69e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 243 TESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARM-YRDELDALREKAVR 321
Cdd:COG4942 145 APARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEE 224
|
90 100
....*....|....*....|....*...
gi 1378869096 322 ----VDKLESEVSRYKERLHDIEFYKAR 345
Cdd:COG4942 225 lealIARLEAEAAAAAERTPAAGFAALK 252
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
727-854 |
3.71e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 41.54 E-value: 3.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 727 NKELESEKEQLKKGLELMKASFKK-TERLEVsyqgLDTENQRLQKALENSNKKIQQL---ESELQDL---EMENQ--TLQ 797
Cdd:smart00787 139 MKLLEGLKEGLDENLEGLKEDYKLlMKELEL----LNSIKPKLRDRKDALEEELRQLkqlEDELEDCdptELDRAkeKLK 214
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1378869096 798 KNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE-NKRLRQQAEIKDTTLEE 854
Cdd:smart00787 215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEiAEAEKKLEQCRGFTFKE 272
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1147-1376 |
3.87e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1147 DLKSLyDSLIKDHekleLLHERQASE-YESLIAKHGTLKSAHKNLE-----VEH----KDLEDRYNQLLKQKGQLEDLEK 1216
Cdd:COG4913 205 PIGDL-DDFVREY----MLEEPDTFEaADALVEHFDDLERAHEALEdareqIELlepiRELAERYAAARERLAELEYLRA 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1217 TLKVE--QEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSllnsSRLEQtrLEAEFSKLKEQ 1294
Cdd:COG4913 280 ALRLWfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG----DRLEQ--LEREIERLERE 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1295 YQQLditSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmlqnRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEE 1374
Cdd:COG4913 354 LEER---ERRRARLEALLAALGLPLPASAEEFAALRAEA----AALLEALEEELEALEEALAEAEAALRDLRRELRELEA 426
|
..
gi 1378869096 1375 KI 1376
Cdd:COG4913 427 EI 428
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
339-1167 |
3.87e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 42.51 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMA 418
Cdd:PTZ00440 545 IKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDEIDNIIQQIEELINEALFNKEKFINEKNDLQEK 624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 419 QKQSMDEsLHLGWELEQISRTSELSEAPQKSL--GHEVNEL------TSSRLLKLE-MENQSLTKTVEELRSTMDSAEGT 489
Cdd:PTZ00440 625 VKYILNK-FYKGDLQELLDELSHFLDDHKYLYheAKSKEDLqtllntSKNEYEKLEfMKSDNIDNIIKNLKKELQNLLSL 703
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 490 TSKILKIEKEN--QRLSKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKT----IETLRENSERQIKILEQENEHL 563
Cdd:PTZ00440 704 KENIIKKQLNNieQDISNSLNQYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRknefILHLYENDKDLPDGKNTYEEFL 783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 564 NQTVSSLRQRSQISAEARV-KDIEKENKILHESIKETSSKL-SKIEFEKRQIRKELEHYKEKGERA--EELENELHHLE- 638
Cdd:PTZ00440 784 QYKDTILNKENKISNDINIlKENKKNNQDLLNSYNILIQKLeAHTEKNDEELKQLLQKFPTEDENLnlKELEKEFNENNq 863
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 639 ------KENELLQKKITNLKITCEKIEALEQENSELERENRKYKKTLDSFKNLTFQLESL------EKEN--SQLDEENL 704
Cdd:PTZ00440 864 ivdniiKDIENMNKNINIIKTLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDniiqknEKLNllNNLNKEKE 943
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 705 ELRRNVESLKCASMKM---AQLQLENKELESEKEQLKKGLELMKASFKKTERLEVSYQGLDTENQRLQKALENSNKK--- 778
Cdd:PTZ00440 944 KIEKQLSDTKINNLKMqieKTLEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILNKKIDDLIKKqhd 1023
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 779 ------IQQLESELQDLEMENQTLQKNLEEL--KISSKRLEQLEKENKS--LEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:PTZ00440 1024 diieliDKLIKEKGKEIEEKVDQYISLLEKMktKLSSFHFNIDIKKYKNpkIKEEIKLLEEKVEALLKKIDENKNKLIEI 1103
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 849 DTTLEENNVKIGNLEKENKTLFKE-----IGIYKESCIRLKELEKENKELVKRATIDiktLVTLREDLVSEKLKTQQMNN 923
Cdd:PTZ00440 1104 KNKSHEHVVNADKEKNKQTEHYNKkkkslEKIYKQMEKTLKELENMNLEDITLNEVN---EIEIEYERILIDHIVEQINN 1180
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 924 DLEKLTHELEKIGLNKERL------LHDEQSTD----------DRYKLLESKLESTLKKSLEIKEEkiAALEARLEESTN 987
Cdd:PTZ00440 1181 EAKKSKTIMEEIESYKKDIdqvkknMSKERNDHlttfeynayyDKATASYENIEELTTEAKGLKGE--ANRSTNVDELKE 1258
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 988 YNQQLRQELKTVKKNYEALKQRQDEEKMVQS----------SPPVSGEDNKWERESQETTRELLKVKDRLIEVERNNATL 1057
Cdd:PTZ00440 1259 IKLQVFSYLQQVIKENNKMENALHEIKNMYEflisidsekiLKEILNSTKKAEEFSNDAKKELEKTDNLIKQVEAKIEQA 1338
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1058 QAEKQALKTQL--KQLETQNNNLQA--QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL---LIQ 1130
Cdd:PTZ00440 1339 KEHKNKIYGSLedKQIDDEIKKIEQikEEISNKRKEINKYLSNIKSNKEKCDLHVRNASRGKDKIDFLNKHEAIepsNSK 1418
|
890 900 910
....*....|....*....|....*....|....*..
gi 1378869096 1131 QSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE 1167
Cdd:PTZ00440 1419 EVNIIKITDNINKCKQYSNEAMETENKADENNDSIIK 1455
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
3.88e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 566 TVSSLRQRSQISAEARvkdiekenKILHESIKETSSKLSKIEFEKRQIRKELEHYKEKGERA--EELENELHHLEKENEL 643
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--------RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRerEELQREEERLVQKEEQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 644 LQKKitnlkitCEKIEALEQensELERENRKykktldsfknLTFQLESLEKENSQLDEENLElrrnVESLKCASMKMAQL 723
Cdd:PRK12705 93 LDAR-------AEKLDNLEN---QLEEREKA----------LSARELELEELEKQLDNELYR----VAGLTPEQARKLLL 148
|
170
....*....|....*....
gi 1378869096 724 QLENKELESEKEQLKKGLE 742
Cdd:PRK12705 149 KLLDAELEEEKAQRVKKIE 167
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
449-587 |
4.17e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.49 E-value: 4.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 449 SLGHEVNELTssRLLKLEME-NQSLTKTVEELRSTMDSAEGTTSKILKIEKEnqrLSKKVEILENEIIQEKQSLQNCQNL 527
Cdd:PRK09039 57 RLNSQIAELA--DLLSLERQgNQDLQDSVANLRASLSAAEAERSRLQALLAE---LAGAGAAAEGRAGELAQELDSEKQV 131
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 528 SKDLMKEKAQLEKTIETLRenseRQIKIL-------EQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Cdd:PRK09039 132 SARALAQVELLNQQIAALR----RQLAALeaaldasEKRDRESQAKIADLGRRLNVALAQRVQELNR 194
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1055-1136 |
4.68e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 41.76 E-value: 4.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1055 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1127
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 1378869096 1128 LIQQS--SLEN 1136
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1038-1378 |
5.32e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1038 RELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQaQILALQRQtvslqeqnttlqtqnaKLQVENSTLNSQS 1117
Cdd:TIGR02169 170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKE----------------KREYEGYELLKEK 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1118 TSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQAS-EYESLIAKHGTLKSAHKNLEVEHKD 1196
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1197 LEDrynqllkqkgQLEDLEKTLKVEQEKMLLKNKNHETVAAEYKKLCGENDRLNHTYNQLLKETEVLQTDHKNLKSLLNS 1276
Cdd:TIGR02169 313 KER----------ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1277 SRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIqtlmlqnrTLLEQNMESKDLFHVEQR 1356
Cdd:TIGR02169 383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI--------NELEEEKEDKALEIKKQE 454
|
330 340
....*....|....*....|..
gi 1378869096 1357 QyidKLNELRRQKEKLEEKIMD 1378
Cdd:TIGR02169 455 W---KLEQLAADLSKYEQELYD 473
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
244-411 |
5.39e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 41.05 E-value: 5.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSarmYRDELDALREKAVRVD 323
Cdd:COG1340 29 EKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNE---LREELDELRKELAELN 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 324 KLESEVSRYKERLHDIEF-YKARVEELKEDNQVLLETKTmLEDQLEGTRarsdKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1340 106 KAGGSIDKLRKEIERLEWrQQTEVLSPEEEKELVEKIKE-LEKELEKAK----KALEKNEKLKELRAELKELRKEAEEIH 180
|
....*....
gi 1378869096 403 KKIEELMEE 411
Cdd:COG1340 181 KKIKELAEE 189
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
882-1013 |
5.45e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 5.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 882 RLKELEKENKELVKRATIDIKTLvtlredlvsEKLKTQQMNNDLEKLTHELEK-IGLNKERLLHDEQSTDDRYKLLESKL 960
Cdd:PRK12704 32 KIKEAEEEAKRILEEAKKEAEAI---------KKEALLEAKEEIHKLRNEFEKeLRERRNELQKLEKRLLQKEENLDRKL 102
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1378869096 961 EStlkksLEIKEEKIAALEARLEestnynqQLRQELKTVKKNYEALKQRQDEE 1013
Cdd:PRK12704 103 EL-----LEKREEELEKKEKELE-------QKQQELEKKEEELEELIEEQLQE 143
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
605-829 |
6.00e-03 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 40.86 E-value: 6.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 605 KIEFEKRQIRKELEHY----KEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENSELERENRKYKKTL 679
Cdd:pfam06008 16 KINYNLENLTKQLQEYlspeNAHKIQIEILEKELSSLAQETEELQKKATQTLAKAQQVnAESERTLGHAKELAEAIKNLI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 680 DSFKNLTFQLESLEKENSQLDEENLElrrnvESLKCASMKMAQLQLEN--KELESEKEQLKKGLELMkasfkktERLEVS 757
Cdd:pfam06008 96 DNIKEINEKVATLGENDFALPSSDLS-----RMLAEAQRMLGEIRSRDfgTQLQNAEAELKAAQDLL-------SRIQTW 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1378869096 758 YQGLDTENQRLQKALENSnkkIQQLESELQDL-----EMENQTLQKNlEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:pfam06008 164 FQSPQEENKALANALRDS---LAEYEAKLSDLrellrEAAAKTRDAN-RLNLANQANLREFQRKKEEVSEQKNQLEE 236
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
524-724 |
6.03e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 41.58 E-value: 6.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 524 CQNLSKDLMKEKAQlektietlRENSERQIKILEQENEHlnqTVSSLRQRSQISAEARVKdiekenkilHESIKETSSKL 603
Cdd:pfam05911 683 NKRLKEEFEQLKSE--------KENLEVELASCTENLES---TKSQLQESEQLIAELRSE---------LASLKESNSLA 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 604 skiefeKRQIRKELEHYKEKGERAEELENELHHLekenellqkkitnlkitCEKIEALEqenSELERENRKYKKTLDSFK 683
Cdd:pfam05911 743 ------ETQLKCMAESYEDLETRLTELEAELNEL-----------------RQKFEALE---VELEEEKNCHEELEAKCL 796
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1378869096 684 NLTFQLESLEKE---NSQLDEENLELRRNVEsLKCASMKMAQLQ 724
Cdd:pfam05911 797 ELQEQLERNEKKessNCDADQEDKKLQQEKE-ITAASEKLAECQ 839
|
|
| WEMBL |
pfam05701 |
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ... |
602-915 |
6.06e-03 |
|
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".
Pssm-ID: 461718 [Multi-domain] Cd Length: 562 Bit Score: 41.55 E-value: 6.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 602 KLSKIEFEKrqIRKELEHYKEKGERAEELEnelHHLEKENELLQKKITNLKITCEKIEALEQ---ENSELerenrkykkt 678
Cdd:pfam05701 38 KLVELELEK--VQEEIPEYKKQSEAAEAAK---AQVLEELESTKRLIEELKLNLERAQTEEAqakQDSEL---------- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 679 ldsfknltFQLESLEKENSQLDEENLELRrnveslkcasmkmaqlqlenKELESEKEQLKKGLELMKASFKKTERLEVSY 758
Cdd:pfam05701 103 --------AKLRVEEMEQGIADEASVAAK--------------------AQLEVAKARHAAAVAELKSVKEELESLRKEY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKNLEelkisSKRLEQLEKENKSL------EQETSQLEKDKK 832
Cdd:pfam05701 155 ASLVSERDIAIKRAEEAVSASKEIEKTVEELTIELIATKESLE-----SAHAAHLEAEEHRIgaalarEQDKLNWEKELK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 833 QLEKENKRLRQQ---AEIKDTTLEENNVKIGNLEKE--------NKTLFKEIGIYKESCIRLKE-LEKENKEL------V 894
Cdd:pfam05701 230 QAEEELQRLNQQllsAKDLKSKLETASALLLDLKAElaaymeskLKEEADGEGNEKKTSTSIQAaLASAKKELeevkanI 309
|
330 340
....*....|....*....|....*
gi 1378869096 895 KRATIDIKTL----VTLREDLVSEK 915
Cdd:pfam05701 310 EKAKDEVNCLrvaaASLRSELEKEK 334
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1058-1226 |
6.16e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 6.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQstsLMNQNAQLLIQQSSLENE 1137
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1138 NESVIKEREDLKSL--------YDSLIKDHEKLELLHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKG 1209
Cdd:COG3883 92 ARALYRSGGSVSYLdvllgsesFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171
|
170
....*....|....*..
gi 1378869096 1210 QLEdlekTLKVEQEKML 1226
Cdd:COG3883 172 ELE----AQQAEQEALL 184
|
|
| TOPEUc |
smart00435 |
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ... |
770-855 |
6.18e-03 |
|
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras
Pssm-ID: 214661 [Multi-domain] Cd Length: 391 Bit Score: 41.18 E-value: 6.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 770 KALENSNKKIQQLESELQDLEMENQTLQKNL---EELKISSKRL-EQLEKENKSLEQETSQLEKDKKQLEKENKRLrQQA 845
Cdd:smart00435 277 KSMEKLQEKIKALKYQLKRLKKMILLFEMISdlkRKLKSKFERDnEKLDAEVKEKKKEKKKEEKKKKQIERLEERI-EKL 355
|
90
....*....|
gi 1378869096 846 EIKDTTLEEN 855
Cdd:smart00435 356 EVQATDKEEN 365
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1050-1298 |
6.19e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 6.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1050 VERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT--VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL 1127
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1128 liqQSSLENENESVIKEREDlkSLYDSLIKDHEKLEllherqaSEYESLIAKHGtlksahknlevehkdleDRYNQLLKQ 1207
Cdd:COG3206 246 ---RAQLGSGPDALPELLQS--PVIQQLRAQLAELE-------AELAELSARYT-----------------PNHPDVIAL 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1208 KGQLEDLEKTLKVEQEKMLlknknhETVAAEYKKLCGENDRLNHTYNQLlkETEVLQtdhknlkslLNSSRLEQTRLEAE 1287
Cdd:COG3206 297 RAQIAALRAQLQQEAQRIL------ASLEAELEALQAREASLQAQLAQL--EARLAE---------LPELEAELRRLERE 359
|
250
....*....|.
gi 1378869096 1288 FSKLKEQYQQL 1298
Cdd:COG3206 360 VEVARELYESL 370
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
917-1126 |
6.27e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 6.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEES----------- 985
Cdd:COG3883 24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDK-LQAEIAEAEAEIEERREELGERaralyrsggsv 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 986 -------------------------TNYNQQLRQELKTVKKNYEALKQRQDEEKmvqssppvsgednkweresqettREL 1040
Cdd:COG3883 103 syldvllgsesfsdfldrlsalskiADADADLLEELKADKAELEAKKAELEAKL-----------------------AEL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1041 LKVKDRLIEVERNNATLQAEKQALktqLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1120
Cdd:COG3883 160 EALKAELEAAKAELEAQQAEQEAL---LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
|
....*.
gi 1378869096 1121 MNQNAQ 1126
Cdd:COG3883 237 AAAAAA 242
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
6.43e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.73 E-value: 6.43e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1378869096 784 SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1045-1210 |
6.56e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 39.53 E-value: 6.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1045 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ-AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1123
Cdd:pfam08614 14 DRTALLEAENAKLQSEPESVLPSTSSSKLSKASPQsASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEKK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1124 NAQLLIQQSSLENENESVIKEREDLkslyDSLIKDHEKLellHERQASEYESLIAKHGTLKSAHKNLEVEHKDLEDRynq 1203
Cdd:pfam08614 94 LREDERRLAALEAERAQLEEKLKDR----EEELREKRKL---NQDLQDELVALQLQLNMAEEKLRKLEKENRELVER--- 163
|
....*..
gi 1378869096 1204 LLKQKGQ 1210
Cdd:pfam08614 164 WMKRKGQ 170
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
625-683 |
6.64e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 40.97 E-value: 6.64e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1378869096 625 ERAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENRKYKKTLDSFK 683
Cdd:PRK03992 1 ERLEALEERNSELEEQIRQLE----------LKLRDLEAENEKLERELERLKSELEKLK 49
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
244-673 |
6.68e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 6.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 244 ESRQHLSVELADAKAKIRR-------LRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELdaLR 316
Cdd:pfam05483 289 EKKDHLTKELEDIKMSLQRsmstqkaLEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEL--LR 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 317 EKAVRVDKLES-------EVSRYKERLHDIEFYKARVE-ELKEDNQVLLETKTMLED---------QLEGT--------R 371
Cdd:pfam05483 367 TEQQRLEKNEDqlkiitmELQKKSSELEEMTKFKNNKEvELEELKKILAEDEKLLDEkkqfekiaeELKGKeqelifllQ 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 372 ARSDKLHELEKENLQLKA-------KLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSE 444
Cdd:pfam05483 447 AREKEIHDLEIQLTAIKTseehylkEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCK 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 445 APQKSLGHEVNELTSSRLL---KLEMENQSLTKTVEELRSTMDSAE----GTTSKILKIEKENQRLSKKVEILENEIIQE 517
Cdd:pfam05483 527 KQEERMLKQIENLEEKEMNlrdELESVREEFIQKGDEVKCKLDKSEenarSIEYEVLKKEKQMKILENKCNNLKKQIENK 606
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 518 KQSLQNCQNLSKDLMKEKAQLEKTI---ETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHE 594
Cdd:pfam05483 607 NKNIEELHQENKALKKKGSAENKQLnayEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADE 686
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 595 SIK-----------ETSSKLSKIEFEKRQIRK-------ELEHYKEKGERAEE----LENELHHLEKENELLQKKITNLK 652
Cdd:pfam05483 687 AVKlqkeidkrcqhKIAEMVALMEKHKHQYDKiieerdsELGLYKNKEQEQSSakaaLEIELSNIKAELLSLKKQLEIEK 766
|
490 500
....*....|....*....|.
gi 1378869096 653 ITCEKIEALEQENSELERENR 673
Cdd:pfam05483 767 EEKEKLKMEAKENTAILKDKK 787
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1094-1336 |
7.01e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.15 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1094 EQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEY 1173
Cdd:PHA02562 178 ELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAAL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1174 ESLIAKHGTLKSAHKNLEVEHKDLEDrynqllkqKGQLEDLEKTLKVEQEKML-LKNKNHEtVAAEYKKLCGENDRLN-- 1250
Cdd:PHA02562 258 NKLNTAAAKIKSKIEQFQKVIKMYEK--------GGVCPTCTQQISEGPDRITkIKDKLKE-LQHSLEKLDTAIDELEei 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1251 -HTYNQLLKETEVLQTDHKNLKSLLNSSRLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLldQ 1329
Cdd:PHA02562 329 mDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHR--G 406
|
....*..
gi 1378869096 1330 IQTLMLQ 1336
Cdd:PHA02562 407 IVTDLLK 413
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
608-732 |
7.60e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.30 E-value: 7.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 608 FEKRQIRKELEHYKEKGER-AEELENELHHLEKENEL-LQKKITNLKITCEK-IEALEQENSELERENRKYKKTLDSfkn 684
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRiLEEAKKEAEAIKKEALLeAKEEIHKLRNEFEKeLRERRNELQKLEKRLLQKEENLDR--- 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1378869096 685 ltfQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE-NKELES 732
Cdd:PRK12704 101 ---KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEqLQELER 146
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
7.68e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 7.68e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1378869096 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
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| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
908-1094 |
9.30e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 9.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 908 REDLVSEKLKTQQMNNDLEKLTHELEK---IGLNKERLLHDEQSTDDRYKLLESK--LESTLKKSLEIKEEKIAALEARL 982
Cdd:pfam17380 305 KEEKAREVERRRKLEEAEKARQAEMDRqaaIYAEQERMAMERERELERIRQEERKreLERIRQEEIAMEISRMRELERLQ 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 983 EESTNYNQQLRQELKTVKKN--YEALKQRQDEEKMVQSSPPVSGEDNKWERESQ----ETTRELLKVkdRLIEVERNNAT 1056
Cdd:pfam17380 385 MERQQKNERVRQELEAARKVkiLEEERQRKIQQQKVEMEQIRAEQEEARQREVRrleeERAREMERV--RLEEQERQQQV 462
|
170 180 190
....*....|....*....|....*....|....*...
gi 1378869096 1057 LQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1094
Cdd:pfam17380 463 ERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1035-1106 |
9.32e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 37.16 E-value: 9.32e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1378869096 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1106
Cdd:cd22887 1 ELESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
784-1144 |
9.91e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 40.71 E-value: 9.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 784 SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR-LRQQAEIKDTTLEENNVKIGNL 862
Cdd:COG5185 201 SGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKlVEQNTDLRLEKLGENAESSKRL 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 863 EKENKTLFKEIGIYKEsciRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDleKLTHELEKiglnkerl 942
Cdd:COG5185 281 NENANNLIKQFENTKE---KIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQ--NLTAEIEQ-------- 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 943 lhDEQSTDDRYKLLESKLESTLKKS-LEIKEEKIAALEARLEESTNYNQQLRQELKTVKKnyEALKQRQDEEKMV-QSSP 1020
Cdd:COG5185 348 --GQESLTENLEAIKEEIENIVGEVeLSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQ--EILATLEDTLKAAdRQIE 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1378869096 1021 PVSGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQlkqleTQNNNLQAQILALQRQTVSLQEQNTTLQ 1100
Cdd:COG5185 424 ELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYD-----EINRSVRSKKEDLNEELTQIESRVSTLK 498
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1378869096 1101 TQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE 1144
Cdd:COG5185 499 ATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542
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