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Conserved domains on  [gi|1377514796|gb|AVY97693|]
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autotransporter outer membrane beta-barrel domain-containing protein [Lelliottia sp. WB101]

Protein Classification

autotransporter outer membrane beta-barrel domain-containing protein( domain architecture ID 13409046)

autotransporter outer membrane beta-barrel domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 728-985 2.04e-48

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


:

Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 172.95  E-value: 2.04e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  728 VWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNlsGNTSTADNYGIIGYAGYTG- 806
Cdd:pfam03797    1 VWARGFGGRGKQDGDGGAAGYDADTGGLQVGADYRLGDNLRLGVAFGYSRSDADVDGR--GGSGDSDSYSLGLYGTYYGd 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  807 DPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETGGn 886
Cdd:pfam03797   79 GGWYLDGGLGYGWHDNDTRRSVDLGGFSETAKGDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFTESGG- 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  887 GMALDVGSTHSQSVVSDIGARIEKTFATGLGSLTPFAQVSWIHQYDNRQVSSHATYAADAvGETSFITKGASPVEDMAGV 966
Cdd:pfam03797  158 AAALSVDSQSYDSLTGRLGLRLSYTFDLGGGTLTPYARLGWRHEFGDDDPVTTAAFAGLS-GAGSFTVAGADLARDSLEL 236

                          250
                   ....*....|....*....
gi 1377514796  967 AIGSTLYDANDLSLDARYD 985
Cdd:pfam03797  237 GAGLSAQLSDNLSLYANYD 255
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 103-1005 3.89e-39

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


:

Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 157.63  E-value: 3.89e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  103 GAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTETGTITGYRG 182
Cdd:COG4625      7 GGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGG 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  183 INNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLISGSA 262
Cdd:COG4625     87 GGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGG 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  263 DAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGN---TA 339
Cdd:COG4625    167 GGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGgggGG 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  340 LYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLLNDNVNAATVQ 419
Cdd:COG4625    247 GAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  420 NRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGGTYQFAEGQRY 499
Cdd:COG4625    327 GGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAG 406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  500 VVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPP 579
Cdd:COG4625    407 GTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTG 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  580 VVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANYIGISSPQLLDLYNAS 659
Cdd:COG4625    487 TTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTILAVAAALDALAGNGDLSALYNA 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  660 LAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGtsgvatgDDYTSNWIVWGQPFGGYARQ 739
Cdd:COG4625    567 LAALDAAAARAALDQLSGEIHASAAAALLQASRALRDALSNRLRALRGAGAAG-------DAAAEGWGVWAQGFGSWGDQ 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  740 DSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNlsGNTSTADNYGIIGYAGYTGDPWYLNLSAGVNR 819
Cdd:COG4625    640 DGDGGAAGYDSSTGGLLVGADYRLGDNWRLGVALGYSRSDVDVDDR--GSSGDSDSYHLGLYGGYQFGALYLDGGLGYGW 717

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  820 QNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPaDVVVTPIASLTYGYQHVDDYKETGGnGMALDVGSTHSQS 899
Cdd:COG4625    718 NDYDTDRTIAFGGLSRTATADYDGDTASAFLEAGYRFDLG-GLTLTPFAGLAYVRLRTDGFTETGG-AAALSVDSQSTDS 795

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  900 VVSDIGARIEKTFATGLG-SLTPFAQVSWIHQYDNRQVSSHATYAADavGETSFITKGASPVEDMAGVAIGSTLYDANDL 978
Cdd:COG4625    796 LRSTLGLRASRTFSLGGGvTLTPSGRLGWRHEFGDDDPSTTASFAGA--PGAAFTVAGAPLARDALVLGAGLSARLSDGL 873

                          890       900
                   ....*....|....*....|....*..
gi 1377514796  979 SLDARYDLQAGERYQAHTFSLRLRKMF 1005
Cdd:COG4625    874 SLGLGYDGEFGSGYTDHGGSAGLRYRF 900
 
Name Accession Description Interval E-value
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 728-985 2.04e-48

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 172.95  E-value: 2.04e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  728 VWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNlsGNTSTADNYGIIGYAGYTG- 806
Cdd:pfam03797    1 VWARGFGGRGKQDGDGGAAGYDADTGGLQVGADYRLGDNLRLGVAFGYSRSDADVDGR--GGSGDSDSYSLGLYGTYYGd 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  807 DPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETGGn 886
Cdd:pfam03797   79 GGWYLDGGLGYGWHDNDTRRSVDLGGFSETAKGDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFTESGG- 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  887 GMALDVGSTHSQSVVSDIGARIEKTFATGLGSLTPFAQVSWIHQYDNRQVSSHATYAADAvGETSFITKGASPVEDMAGV 966
Cdd:pfam03797  158 AAALSVDSQSYDSLTGRLGLRLSYTFDLGGGTLTPYARLGWRHEFGDDDPVTTAAFAGLS-GAGSFTVAGADLARDSLEL 236

                          250
                   ....*....|....*....
gi 1377514796  967 AIGSTLYDANDLSLDARYD 985
Cdd:pfam03797  237 GAGLSAQLSDNLSLYANYD 255
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 103-1005 3.89e-39

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 157.63  E-value: 3.89e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  103 GAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTETGTITGYRG 182
Cdd:COG4625      7 GGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGG 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  183 INNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLISGSA 262
Cdd:COG4625     87 GGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGG 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  263 DAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGN---TA 339
Cdd:COG4625    167 GGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGgggGG 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  340 LYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLLNDNVNAATVQ 419
Cdd:COG4625    247 GAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  420 NRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGGTYQFAEGQRY 499
Cdd:COG4625    327 GGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAG 406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  500 VVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPP 579
Cdd:COG4625    407 GTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTG 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  580 VVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANYIGISSPQLLDLYNAS 659
Cdd:COG4625    487 TTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTILAVAAALDALAGNGDLSALYNA 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  660 LAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGtsgvatgDDYTSNWIVWGQPFGGYARQ 739
Cdd:COG4625    567 LAALDAAAARAALDQLSGEIHASAAAALLQASRALRDALSNRLRALRGAGAAG-------DAAAEGWGVWAQGFGSWGDQ 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  740 DSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNlsGNTSTADNYGIIGYAGYTGDPWYLNLSAGVNR 819
Cdd:COG4625    640 DGDGGAAGYDSSTGGLLVGADYRLGDNWRLGVALGYSRSDVDVDDR--GSSGDSDSYHLGLYGGYQFGALYLDGGLGYGW 717

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  820 QNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPaDVVVTPIASLTYGYQHVDDYKETGGnGMALDVGSTHSQS 899
Cdd:COG4625    718 NDYDTDRTIAFGGLSRTATADYDGDTASAFLEAGYRFDLG-GLTLTPFAGLAYVRLRTDGFTETGG-AAALSVDSQSTDS 795

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  900 VVSDIGARIEKTFATGLG-SLTPFAQVSWIHQYDNRQVSSHATYAADavGETSFITKGASPVEDMAGVAIGSTLYDANDL 978
Cdd:COG4625    796 LRSTLGLRASRTFSLGGGvTLTPSGRLGWRHEFGDDDPSTTASFAGA--PGAAFTVAGAPLARDALVLGAGLSARLSDGL 873

                          890       900
                   ....*....|....*....|....*..
gi 1377514796  979 SLDARYDLQAGERYQAHTFSLRLRKMF 1005
Cdd:COG4625    874 SLGLGYDGEFGSGYTDHGGSAGLRYRF 900
Autotransporter smart00869
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 730-995 1.15e-35

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 136.55  E-value: 1.15e-35
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   730 GQPFGGYARQDSS--AEISGYTAKFGGLILGADRSLGDD--WRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGYT 805
Cdd:smart00869    1 GRGLGGFLRQDSSgsGGSAGFDYDSYGLQLGADYRLSDNgnLSLGFAAGYGNSKVDFSGNKGSGKGDVDSYGLGLYAGYS 80

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   806 -GDPWYLNLSAGVNRQNYSSVRRADFTGFsGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETG 884
Cdd:smart00869   81 lGNGLYLDAQLGYGRSDNDTKRKVTLGGA-GRAKGSYDGTGYGASLEAGYRFYLGGGLTLTPFAGLAYSRVRQDGFTESG 159

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   885 GNGMALDVGSTHSQSVVSDIGARIEKTFATGLGS-LTPFAQVSWIHQYDNRQVSSHATYAADAvgeTSFITKGASPVEDM 963
Cdd:smart00869  160 GGAFGLSVDSQSLDSLSLPLGLRLEYRLALGDGAtLTPYLRLAYVHDFYDDNPVVTASLLGSG---ASFTTSGTDLDRNA 236

                           250       260       270
                    ....*....|....*....|....*....|..
gi 1377514796   964 AGVAIGSTLYDANDLSLDARYDLQAGERYQAH 995
Cdd:smart00869  237 AELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
autotrans_barl TIGR01414
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
 728-933 3.31e-20

outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 273608 [Multi-domain]  Cd Length: 431  Bit Score: 94.76  E-value: 3.31e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  728 VWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLG----DDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAG 803
Cdd:TIGR01414  165 VWARIFGGDNHLDGDAGAAGYDQNTTGVQLGGDILLAgnadGDLHVGLMAGYAKADIKTRSYKYGGKGKVDGYGLGLYGT 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  804 YTGDP-WYLNLSAGVNRQNYSsvrrADFTGFSGAAQGKFNGQSVTLQTEFGYPVTL-PADVVVTPIASLTYGYQHVDDYK 881
Cdd:TIGR01414  245 WLQDSgAYVDGVLQYSRFRND----VSSTGSNGKVSGKYNSNGFTASLEAGYRYNLgGNGWYVEPQAQLSYFGVSGDDYK 320

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1377514796  882 ETggNGMALDVGSTHsqSVVSDIGARIEKTFATGLGS-LTPFAQVSWIHQYDN 933
Cdd:TIGR01414  321 ES--NGTRVLGGGGD--SLQGRLGLRVGYQFDLGTGRaVKPYLKANVLHEFKG 369
YhjY COG5571
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
 712-996 3.30e-15

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 80.31  E-value: 3.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  712 GTSGVATGDDYTSNWIVWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSntsvHGKGNLSGNTS 791
Cdd:COG5571    363 RSLAVAAGQGRGARGGQTRGGGGAGGTTGGGVGAGGGDGDGPNLTLGVDYRLSDNLLLGAALSYG----RQDLDFGDGGS 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  792 -TADNYGIIGYAGYTGDPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYpvTLPADVV-VTPIAS 869
Cdd:COG5571    439 yDARSTSLSLYAGYRAGGLWVDADLSYGDLDYDIRRHIRLGPATRTETGDTDGSQWGARLTAGY--DFTAGRLrTGPFAG 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  870 LTYGYQHVDDYKETGGNGMALDVGSTHSQSVVSDIGARIEKTFatgLGSLTPFAQVSWIHQYDNRQVSSHATYAADAVGe 949
Cdd:COG5571    517 LDYQKVKVDGYTETGAGSTALSFGDQDRDSLVGSLGWRADYQL---LGRFNPYAEVAYEHEFGDDDRDVTAGLASLPAG- 592

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1377514796  950 tSFITKGASPVEDMAGVAIGSTLYDANDLSLDARYDLQAGERYQAHT 996
Cdd:COG5571    593 -SFSLPAAAPDKNWGRATLGASAALTNGVSLFAGYSGTFGRDDGRQT 638
 
Name Accession Description Interval E-value
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 728-985 2.04e-48

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 172.95  E-value: 2.04e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  728 VWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNlsGNTSTADNYGIIGYAGYTG- 806
Cdd:pfam03797    1 VWARGFGGRGKQDGDGGAAGYDADTGGLQVGADYRLGDNLRLGVAFGYSRSDADVDGR--GGSGDSDSYSLGLYGTYYGd 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  807 DPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETGGn 886
Cdd:pfam03797   79 GGWYLDGGLGYGWHDNDTRRSVDLGGFSETAKGDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFTESGG- 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  887 GMALDVGSTHSQSVVSDIGARIEKTFATGLGSLTPFAQVSWIHQYDNRQVSSHATYAADAvGETSFITKGASPVEDMAGV 966
Cdd:pfam03797  158 AAALSVDSQSYDSLTGRLGLRLSYTFDLGGGTLTPYARLGWRHEFGDDDPVTTAAFAGLS-GAGSFTVAGADLARDSLEL 236

                          250
                   ....*....|....*....
gi 1377514796  967 AIGSTLYDANDLSLDARYD 985
Cdd:pfam03797  237 GAGLSAQLSDNLSLYANYD 255
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 103-1005 3.89e-39

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 157.63  E-value: 3.89e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  103 GAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTETGTITGYRG 182
Cdd:COG4625      7 GGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGG 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  183 INNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLISGSA 262
Cdd:COG4625     87 GGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGG 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  263 DAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGN---TA 339
Cdd:COG4625    167 GGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGgggGG 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  340 LYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLLNDNVNAATVQ 419
Cdd:COG4625    247 GAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  420 NRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGGTYQFAEGQRY 499
Cdd:COG4625    327 GGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAG 406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  500 VVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPP 579
Cdd:COG4625    407 GTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTG 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  580 VVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANYIGISSPQLLDLYNAS 659
Cdd:COG4625    487 TTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTILAVAAALDALAGNGDLSALYNA 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  660 LAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGtsgvatgDDYTSNWIVWGQPFGGYARQ 739
Cdd:COG4625    567 LAALDAAAARAALDQLSGEIHASAAAALLQASRALRDALSNRLRALRGAGAAG-------DAAAEGWGVWAQGFGSWGDQ 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  740 DSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNlsGNTSTADNYGIIGYAGYTGDPWYLNLSAGVNR 819
Cdd:COG4625    640 DGDGGAAGYDSSTGGLLVGADYRLGDNWRLGVALGYSRSDVDVDDR--GSSGDSDSYHLGLYGGYQFGALYLDGGLGYGW 717

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  820 QNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPaDVVVTPIASLTYGYQHVDDYKETGGnGMALDVGSTHSQS 899
Cdd:COG4625    718 NDYDTDRTIAFGGLSRTATADYDGDTASAFLEAGYRFDLG-GLTLTPFAGLAYVRLRTDGFTETGG-AAALSVDSQSTDS 795

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  900 VVSDIGARIEKTFATGLG-SLTPFAQVSWIHQYDNRQVSSHATYAADavGETSFITKGASPVEDMAGVAIGSTLYDANDL 978
Cdd:COG4625    796 LRSTLGLRASRTFSLGGGvTLTPSGRLGWRHEFGDDDPSTTASFAGA--PGAAFTVAGAPLARDALVLGAGLSARLSDGL 873

                          890       900
                   ....*....|....*....|....*..
gi 1377514796  979 SLDARYDLQAGERYQAHTFSLRLRKMF 1005
Cdd:COG4625    874 SLGLGYDGEFGSGYTDHGGSAGLRYRF 900
Autotransporter smart00869
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
 730-995 1.15e-35

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 136.55  E-value: 1.15e-35
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   730 GQPFGGYARQDSS--AEISGYTAKFGGLILGADRSLGDD--WRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGYT 805
Cdd:smart00869    1 GRGLGGFLRQDSSgsGGSAGFDYDSYGLQLGADYRLSDNgnLSLGFAAGYGNSKVDFSGNKGSGKGDVDSYGLGLYAGYS 80

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   806 -GDPWYLNLSAGVNRQNYSSVRRADFTGFsGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETG 884
Cdd:smart00869   81 lGNGLYLDAQLGYGRSDNDTKRKVTLGGA-GRAKGSYDGTGYGASLEAGYRFYLGGGLTLTPFAGLAYSRVRQDGFTESG 159

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   885 GNGMALDVGSTHSQSVVSDIGARIEKTFATGLGS-LTPFAQVSWIHQYDNRQVSSHATYAADAvgeTSFITKGASPVEDM 963
Cdd:smart00869  160 GGAFGLSVDSQSLDSLSLPLGLRLEYRLALGDGAtLTPYLRLAYVHDFYDDNPVVTASLLGSG---ASFTTSGTDLDRNA 236

                           250       260       270
                    ....*....|....*....|....*....|..
gi 1377514796   964 AGVAIGSTLYDANDLSLDARYDLQAGERYQAH 995
Cdd:smart00869  237 AELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
autotrans_barl TIGR01414
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
 728-933 3.31e-20

outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 273608 [Multi-domain]  Cd Length: 431  Bit Score: 94.76  E-value: 3.31e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  728 VWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLG----DDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAG 803
Cdd:TIGR01414  165 VWARIFGGDNHLDGDAGAAGYDQNTTGVQLGGDILLAgnadGDLHVGLMAGYAKADIKTRSYKYGGKGKVDGYGLGLYGT 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  804 YTGDP-WYLNLSAGVNRQNYSsvrrADFTGFSGAAQGKFNGQSVTLQTEFGYPVTL-PADVVVTPIASLTYGYQHVDDYK 881
Cdd:TIGR01414  245 WLQDSgAYVDGVLQYSRFRND----VSSTGSNGKVSGKYNSNGFTASLEAGYRYNLgGNGWYVEPQAQLSYFGVSGDDYK 320

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1377514796  882 ETggNGMALDVGSTHsqSVVSDIGARIEKTFATGLGS-LTPFAQVSWIHQYDN 933
Cdd:TIGR01414  321 ES--NGTRVLGGGGD--SLQGRLGLRVGYQFDLGTGRaVKPYLKANVLHEFKG 369
YhjY COG5571
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
 712-996 3.30e-15

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 80.31  E-value: 3.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  712 GTSGVATGDDYTSNWIVWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSntsvHGKGNLSGNTS 791
Cdd:COG5571    363 RSLAVAAGQGRGARGGQTRGGGGAGGTTGGGVGAGGGDGDGPNLTLGVDYRLSDNLLLGAALSYG----RQDLDFGDGGS 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  792 -TADNYGIIGYAGYTGDPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYpvTLPADVV-VTPIAS 869
Cdd:COG5571    439 yDARSTSLSLYAGYRAGGLWVDADLSYGDLDYDIRRHIRLGPATRTETGDTDGSQWGARLTAGY--DFTAGRLrTGPFAG 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  870 LTYGYQHVDDYKETGGNGMALDVGSTHSQSVVSDIGARIEKTFatgLGSLTPFAQVSWIHQYDNRQVSSHATYAADAVGe 949
Cdd:COG5571    517 LDYQKVKVDGYTETGAGSTALSFGDQDRDSLVGSLGWRADYQL---LGRFNPYAEVAYEHEFGDDDRDVTAGLASLPAG- 592

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1377514796  950 tSFITKGASPVEDMAGVAIGSTLYDANDLSLDARYDLQAGERYQAHT 996
Cdd:COG5571    593 -SFSLPAAAPDKNWGRATLGASAALTNGVSLFAGYSGTFGRDDGRQT 638
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 21-847 1.20e-09

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 62.86  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   21 GLLTTHSIAASEVIIDAPMSGLQVLGSN-DVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISDNNLPFSMNVV 99
Cdd:COG3210    791 GAEISIDITADGTITAAGTTAINVTGSGgTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSL 870

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  100 QIDGAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTETGTITG 179
Cdd:COG3210    871 AATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQG 950

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  180 YRGINNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLIS 259
Cdd:COG3210    951 NAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTAS 1030

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  260 GSADAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGNTA 339
Cdd:COG3210   1031 ATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTT 1110

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  340 LYIYTDTNASADITLTNNG--VVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLLNDNVNAAT 417
Cdd:COG3210   1111 TSTGGVTASKVGGTTTVGAtgTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAAT 1190

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  418 VQNRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGGTYQFAEGQ 497
Cdd:COG3210   1191 EGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGAT 1270

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  498 RYVVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPPVVTPPVVTPPVVT 577
Cdd:COG3210   1271 STVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANGATVGTGIGGTTATGTAVAAVNSGGVNAGGGTINTTAANT 1350

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  578 PPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANYIGISSPQLLDLYN 657
Cdd:COG3210   1351 GLNGGNGATDSAAGAGSGGAAGSLAATAGAGTVLTGAGNNTGAEGTNAGRDGGVTTSGTGVGNNGGVSGTTVAGTTGSSA 1430

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  658 ASLAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGTSGVATGDDYTSNWIVWGQPFGGYA 737
Cdd:COG3210   1431 TTGTGGTGNTTGTSVAGAGGGNADASAINTGNASSLGAGGSTAGNAVGGAVIGGTTTGGNGAGVAGATASNGGTSTGAGG 1510

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  738 RQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGYTGDPWYLNLSAGV 817
Cdd:COG3210   1511 TAGGTTAEVAKASLEGGEGTYGGSSVAEAGTGGGILGAVSGAGSEGGAAGGVTGSVGVGGTDGAGGDTGGADDTGAQAPT 1590

                          810       820       830
                   ....*....|....*....|....*....|
gi 1377514796  818 NRQNYSSVRRADFTGFSGAAQGKFNGQSVT 847
Cdd:COG3210   1591 AGNTATLTLSLAEGTNAEYGGTTNVTSGTA 1620
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 40-920 3.37e-09

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 61.32  E-value: 3.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   40 SGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQ--GATVTTFTNEGLITDISDNNLPFSMNVVQIDGAAGTFENNGIIQSV 117
Cdd:COG3210    785 ATLDNAGAEISIDITADGTITAAGTTAINVTGsgGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAG 864

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  118 NQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTETGTITGYRGINNLGTIDSLTNAGV 197
Cdd:COG3210    865 ANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTA 944

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  198 ITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLISGSADAITNYGTVGTLENN 277
Cdd:COG3210    945 LSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTG 1024

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  278 GRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGNTALYIYTDTNASADITLTNN 357
Cdd:COG3210   1025 TTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATG 1104

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  358 GVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLLNDNVNAATVQNRGASLQVNTDITIAGDY 437
Cdd:COG3210   1105 TSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGG 1184

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  438 HQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGGTYQFAEGQRYVVINAAGSGTDYNADKLN 517
Cdd:COG3210   1185 ADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGA 1264

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  518 YSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVT 597
Cdd:COG3210   1265 VSNGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANGATVGTGIGGTTATGTAVAAVNSGGVNAGGGTIN 1344

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  598 PPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANYIGISSPQLLDLYNASLAIQGKDEANRAGEKLSP 677
Cdd:COG3210   1345 TTAANTGLNGGNGATDSAAGAGSGGAAGSLAATAGAGTVLTGAGNNTGAEGTNAGRDGGVTTSGTGVGNNGGVSGTTVAG 1424

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  678 GQNINTSSAAAVATSTAQAVVGAHIDA-----VRNPHTSGTSGVATGDDYTSNWIVWGQPFGGYARQDSSAEISGYTAKF 752
Cdd:COG3210   1425 TTGSSATTGTGGTGNTTGTSVAGAGGGnadasAINTGNASSLGAGGSTAGNAVGGAVIGGTTTGGNGAGVAGATASNGGT 1504

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  753 GGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGYTGDPWYLNLSAGVNRQNYSSVRRADFTG 832
Cdd:COG3210   1505 STGAGGTAGGTTAEVAKASLEGGEGTYGGSSVAEAGTGGGILGAVSGAGSEGGAAGGVTGSVGVGGTDGAGGDTGGADDT 1584

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  833 FSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETGGNGMALDVGSTHSQSVVSDIGARIEKTF 912
Cdd:COG3210   1585 GAQAPTAGNTATLTLSLAEGTNAEYGGTTNVTSGTAGNAGATGANSNTVVTTNGGEGVLALVAGGNTTNGTTLSGAVNGA 1664


                   ....*...
gi 1377514796  913 ATGLGSLT 920
Cdd:COG3210   1665 GNGWAVDL 1672
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 15-982 2.15e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 58.62  E-value: 2.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   15 ASTAAQGLLTTHSIAASEVIIDAPMSGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISDNNLPF 94
Cdd:COG3210    568 GVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTG 647

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   95 SMNVVQIDGAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTET 174
Cdd:COG3210    648 SGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGALANANG 727

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  175 GTITGYRGINNLGTI----------DSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVI 244
Cdd:COG3210    728 DTVTFGNLGTGATLTlnagvtitsgNAGTLSIGLTANTTASGTTLTLANANGNTSAGATLDNAGAEISIDITADGTITAA 807

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  245 NWGTINTLINDNLISGSADAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPA 324
Cdd:COG3210    808 GTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATS 887

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  325 TQIINNGTLSGGNTALYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGT 404
Cdd:COG3210    888 TGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTG 967

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  405 GSLLLNDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINL 484
Cdd:COG3210    968 ASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVG 1047

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  485 VRTGGTYQFAEGQRYVVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPP 564
Cdd:COG3210   1048 VNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTV 1127

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  565 VVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANY 644
Cdd:COG3210   1128 GATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGS 1207

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  645 IGISSPQLLDLYNASLAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGTSGVATGDDYTS 724
Cdd:COG3210   1208 TTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVD 1287

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  725 NWIVWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGY 804
Cdd:COG3210   1288 IGSTSATSAGGSLDTTGNTAGANGATVGTGIGGTTATGTAVAAVNSGGVNAGGGTINTTAANTGLNGGNGATDSAAGAGS 1367

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  805 TGDPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETG 884
Cdd:COG3210   1368 GGAAGSLAATAGAGTVLTGAGNNTGAEGTNAGRDGGVTTSGTGVGNNGGVSGTTVAGTTGSSATTGTGGTGNTTGTSVAG 1447

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  885 GNGMALDVGSTHSQSVVSDIGARIEKTFATGLGSLTPFAQVSWIHQYDNRQVSSHATYAADAVGETSFITKGASPVEDMA 964
Cdd:COG3210   1448 AGGGNADASAINTGNASSLGAGGSTAGNAVGGAVIGGTTTGGNGAGVAGATASNGGTSTGAGGTAGGTTAEVAKASLEGG 1527

                          970
                   ....*....|....*...
gi 1377514796  965 GVAIGSTLYDANDLSLDA 982
Cdd:COG3210   1528 EGTYGGSSVAEAGTGGGI 1545
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-438 2.33e-08

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 58.03  E-value: 2.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   10 ISLLVASTAAQGLLTTHSIAASEVIIDAPMSGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISD 89
Cdd:COG3468      7 GGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGTGG 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   90 NNLPFSMNVVQIDGAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNL 169
Cdd:COG3468     87 NSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSGGG 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  170 TNTETGTITGYRGINNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTI 249
Cdd:COG3468    167 GSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGSAG 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  250 NTLINDNLISGSADAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIIN 329
Cdd:COG3468    247 GTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSNAGGGS 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  330 NGTLSGGNTALYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLL 409
Cdd:COG3468    327 GGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNGGG 406

                          410       420
                   ....*....|....*....|....*....
gi 1377514796  410 NDNVNAAtvqnrGASLQVNTDITIAGDYH 438
Cdd:COG3468    407 GVGGGGG-----GGLTLTGGTLTVNGNYT 430
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 46-509 8.69e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 56.70  E-value: 8.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   46 GSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISDNNLPFSMNVVQIDGAAGTFENNGIIQSVNQYHYGSI 125
Cdd:COG3210    280 TNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLGGGTAAGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNGTTGTGA 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  126 VELSASGVVDNFINRGTIQNSLNNFNMGMDNTGsveNNGHILNLTNTETGTITGYRGINNLGTIDSLTNAGVITAANNNF 205
Cdd:COG3210    360 GSGLTGTGNGGGLTTAGAGTVASTVGTATASTG---NASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGIT 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  206 MPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLISGSADAITNYGTVGTLENNGRIAAINN 285
Cdd:COG3210    437 GNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTG 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  286 GIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGNTALYIYTDTNASADITLTNNGVVKGDIY 365
Cdd:COG3210    517 ITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNS 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  366 SQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLLNDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAAL 445
Cdd:COG3210    597 GGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTG 676

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1377514796  446 ISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGGTYQFAEGQRYVVINAAGSGT 509
Cdd:COG3210    677 TVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGALANANGDTVTFGNLGTGAT 740
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 53-480 1.34e-07

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 55.72  E-value: 1.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   53 VTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISDNNLPFSMNVVQIDGAAGTFENNGIIQSVNQYHYGSIVELSASG 132
Cdd:COG3468      5 GGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGT 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  133 VVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTETGTITGYRGINNLGTIDSLTNAGVITAANNNFMPMPGQN 212
Cdd:COG3468     85 GGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSG 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  213 GAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINTLINDNLISGSADAITNYGTVGTLENNGRIAAINNGIFASSS 292
Cdd:COG3468    165 GGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGS 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  293 DGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNGTLSGGNTALYIYTDTNASADITLTNNGVVKGDIYSQSAAPL 372
Cdd:COG3468    245 AGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSNAGG 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  373 LINGGSTTTGTLTGQNGTGT---LTSQHSDVIFGTGSLLLNDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAALISGI 449
Cdd:COG3468    325 GSGGGGGGGGGGGGGGTTLNgagSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNG 404

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1377514796  450 SDLATQNGTLMADSGYGRLNVTGNATIEEGS 480
Cdd:COG3468    405 GGGVGGGGGGGLTLTGGTLTVNGNYTGNNGT 435
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 728-933 7.52e-07

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 53.41  E-value: 7.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  728 VWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDD----WRLGAAVNYSNTSVHGKGNLSGN-TSTADNYGIIGYA 802
Cdd:COG3468    579 AWLRVEGGHNRSRDSSGQLDYDSNRYGLQLGGDLLQWEDgggrLHVGVMAGYGNGDSDVRSRATGTgKGDVDGYSLGLYG 658

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  803 GYTGDP-WYLNLSAGVNRQNySSVRradfTGFSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYK 881
Cdd:COG3468    659 TWYGNNgFYVDGVLQYSWFD-NDVS----SDDLGGVTGSYDGNGYSASLEAGYPFKLGEGWSLEPQAQLIYQGVDFDDFT 733

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1377514796  882 ETGGngmaLDVGSTHSQSVVSDIGARIEKTFATGLGS-LTPFAQVSWIHQYDN 933
Cdd:COG3468    734 DSNG----TRVSGDDGDSLQGRLGLRLGYEFHWDDGRaLQPYLEANWLHEFLG 782
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 15-977 2.45e-06

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 51.69  E-value: 2.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   15 ASTAAQGLLTTHSIAASEVIIDAPMSGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISDNNLPF 94
Cdd:COG3210    476 AGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGT 555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   95 SMNVVQIDGAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTNTET 174
Cdd:COG3210    556 TAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLT 635

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  175 GTITGYRGINNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAG---VINWGTINT 251
Cdd:COG3210    636 GSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGntlTISTGSITV 715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  252 LINDNLISGSADAITNYGTVgtleNNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNG 331
Cdd:COG3210    716 TGQIGALANANGDTVTFGNL----GTGATLTLNAGVTITSGNAGTLSIGLTANTTASGTTLTLANANGNTSAGATLDNAG 791

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  332 TLSGG--NTALYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTGSLLL 409
Cdd:COG3210    792 AEISIdiTADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLA 871

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  410 NDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLVRTGG 489
Cdd:COG3210    872 ATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGN 951

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  490 TYQFAEGQRYVVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPPVVTPP 569
Cdd:COG3210    952 AGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASA 1031

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  570 VVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANYIGISS 649
Cdd:COG3210   1032 TGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTT 1111

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  650 PQLLDLYNASLAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGTSGVATGDDYTSNWIVW 729
Cdd:COG3210   1112 STGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATE 1191

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  730 GQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGYTGDPW 809
Cdd:COG3210   1192 GTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATS 1271

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  810 YLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTLQTEFGYPVTLPADVVVTPIASLTYGYQHVDDYKETGGNGMA 889
Cdd:COG3210   1272 TVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANGATVGTGIGGTTATGTAVAAVNSGGVNAGGGTINTTAANTG 1351

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  890 LDVGSTHSQSVVSDIGARIEKTFATGLGSLTPFAQVSWIHQYDNRQVSSHATYAADAVGETSFITKGASPVEDMAGVAIG 969
Cdd:COG3210   1352 LNGGNGATDSAAGAGSGGAAGSLAATAGAGTVLTGAGNNTGAEGTNAGRDGGVTTSGTGVGNNGGVSGTTVAGTTGSSAT 1431


                   ....*...
gi 1377514796  970 STLYDAND 977
Cdd:COG3210   1432 TGTGGTGN 1439
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 9-848 2.81e-06

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 51.69  E-value: 2.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796    9 LISLLVASTAAQGLLTTHSIAASEVIIDAPMSGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDIS 88
Cdd:COG3210    443 GGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGG 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   89 DNNLPFSMNVVQIDGAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILN 168
Cdd:COG3210    523 GGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLS 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  169 LTNTETGTITGYRGINNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGT 248
Cdd:COG3210    603 IGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGA 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  249 INTLINDNLISGSADAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQII 328
Cdd:COG3210    683 TGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGALANANGDTVTFGNLGTGATLTLNAGVTITSGNAGTLSIGLT 762

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  329 NNGTLSGGNTALYIYTDTNASADITLTNNGVVKGDIYS----QSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGT 404
Cdd:COG3210    763 ANTTASGTTLTLANANGNTSAGATLDNAGAEISIDITAdgtiTAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGG 842

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  405 GSLLLNDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINL 484
Cdd:COG3210    843 SNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTG 922

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  485 VRTGGTYQFAEGQRYVVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTDKALVLTVGAEPPVVTPPVVTPPVVTPP 564
Cdd:COG3210    923 GGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNS 1002

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  565 VVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPVVTPPTQPTPKPALATIPSASAALGGLANY 644
Cdd:COG3210   1003 GTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGT 1082

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  645 IGISSPQLLDLYNASLAIQGKDEANRAGEKLSPGQNINTSSAAAVATSTAQAVVGAHIDAVRNPHTSGTSGVATGDDYTS 724
Cdd:COG3210   1083 AQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSAS 1162

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  725 NWIVWGQPFGGYARQDSSAEISGYTAKFGGLILGADRSLGDDWRLGAAVNYSNTSVHGKGNLSGNTSTADNYGIIGYAGY 804
Cdd:COG3210   1163 AGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTG 1242

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1377514796  805 TGDPWYLNLSAGVNRQNYSSVRRADFTGFSGAAQGKFNGQSVTL 848
Cdd:COG3210   1243 SFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTV 1286
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 7-530 1.02e-05

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 49.76  E-value: 1.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796    7 SQLISLLVASTAAQGLLTTHSIAASEVIIDAPMSGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITD 86
Cdd:COG3210    199 GALINATAGVLANAGGGTAGGVASANSTLTGGVVAAGTGAGVISTGGTDISSLSVAAGAGTGGAGGTGNAGNTTIGTTVT 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   87 ISDNNLPFSMNVVQIDGAAGTFENNGIIQSVNQY---HYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENN 163
Cdd:COG3210    279 GTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLgggTAAGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNGTTGTG 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  164 GHILNLTNTETGTITGYRGINNLGTIDSLTNAGVITAANNNFMPMPGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGV 243
Cdd:COG3210    359 AGSGLTGTGNGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGN 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  244 INWGTINTLINDNLISGSADAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNP 323
Cdd:COG3210    439 GTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGIT 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  324 ATQIINNGTLSGGNTALYIYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFG 403
Cdd:COG3210    519 AGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGG 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  404 TGSLLLNDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSIN 483
Cdd:COG3210    599 TVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTV 678

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1377514796  484 LVRTGGTYQFAEGQRYVVINAAGSGTDYNADKLNYSAIGYRGAVSGS 530
Cdd:COG3210    679 TSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGALANA 725
Hia COG5295
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
 14-537 1.18e-03

Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444098 [Multi-domain]  Cd Length: 785  Bit Score: 42.84  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   14 VASTAAQGLLTTHSIAASEVIIDAPMSGLQVLGSNDVIRVTNTGSLSGAPTTALTLQQGATVTTFTNEGLITDISDNNLP 93
Cdd:COG5295     73 GGTSATAASSVASGGASAATAASTGTGNTAGTAATVAGAASSGSATNAGASAGASAAAAAGSTAAAGGAAASTGGSSAAG 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796   94 --FSMNVVQIDGAAGTFENNGIIQSVNQYHYGSIVELSASGVVDNFINRGTIQNSLNNFNMGMDNTGSVENNGHILNLTN 171
Cdd:COG5295    153 gsNTATATGSSTANAATAAAGATSTSASGSSSGASGAAAASAATGASAGGTASAAASASSSATGTSASVGVNAGAATGSA 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  172 TETGTITGYRGINNLGTIDSLTNAGVITAANNNfmpmpGQNGAIYNRGIIGTLHNTGTLQTGTLNYFGSAGVINWGTINT 251
Cdd:COG5295    233 ASAGGSASAGAASGNATTASASSVSGSAVAAGT-----ASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANAT 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  252 LINDNLISGSADAITNYGTVGTLENNGRIAAINNGIFASSSDGNAIAEIVNNGEISGGYYGIYLASYSNQNPATQIINNG 331
Cdd:COG5295    308 AGGGNAGSGGGGAAALGSAGGSSGVGTASGASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNA 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  332 TLSGGNTALY------IYTDTNASADITLTNNGVVKGDIYSQSAAPLLINGGSTTTGTLTGQNGTGTLTSQHSDVIFGTG 405
Cdd:COG5295    388 AGAAGAGSAGsggsstGASAGGGASAAGGAAAGSAAAGTSSNTSAVGASNGASGTSSSASSAGAAGGGTAGAGGAANVGA 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1377514796  406 SLLLNDNVNAATVQNRGASLQVNTDITIAGDYHQKAAAALISGISDLATQNGTLMADSGYGRLNVTGNATIEEGSSINLV 485
Cdd:COG5295    468 ATTAASAAATAAAATSSAAIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGST 547

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1377514796  486 --RTGGTYQFAEGQRYVVINAAGSGTDYNADKLNYSAIGYRGAVSGSVYETGTD 537
Cdd:COG5295    548 taATGTNSVAVGNNTATGANSVALGAGSVASGANSVSVGAAGAENVAAGATDTD 601
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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