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Conserved domains on  [gi|1375632526|gb|AVW81367|]
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regulatory protein ICP22 [Felid alphaherpesvirus 1]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Herpes_IE68 super family cl03612
Herpesvirus immediate early protein; This regulatory protein is expressed from an immediate ...
 104-236 7.80e-32

Herpesvirus immediate early protein; This regulatory protein is expressed from an immediate early gene in the cell cycle of herpesvirus. The protein is known by various names including IE-68, US1, ICP22 and IR4.


The actual alignment was detected with superfamily member pfam02479:

Pssm-ID: 280616  Cd Length: 132  Bit Score: 115.81  E-value: 7.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375632526 104 HPEYGSvvaSRDLRAYLTHGPGAFCSPPWRCDLKRLMKDVNIMFRCIATSSVNVSSDSRALRRALLDFYIMGYTNQRPTR 183
Cdd:pfam02479   1 GPEYGS---DRSDRQAQLRSVGAFCPLPWTPDLARLRQDINQLFRCILRCALNPGGSANRLRRLLRDCYLMGRCRYRLKP 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1375632526 184 ACWETLLQLSSEQARPLRATLRHLN--TTEP-CDRRFLEPPtQVPPILFGQECDVS 236
Cdd:pfam02479  78 ATWERLLQLSPTQSLHLRNTLREVEarSAEPvCELPCIEAS-DSIFHRYAPECDVS 132
 
Name Accession Description Interval E-value
Herpes_IE68 pfam02479
Herpesvirus immediate early protein; This regulatory protein is expressed from an immediate ...
 104-236 7.80e-32

Herpesvirus immediate early protein; This regulatory protein is expressed from an immediate early gene in the cell cycle of herpesvirus. The protein is known by various names including IE-68, US1, ICP22 and IR4.


Pssm-ID: 280616  Cd Length: 132  Bit Score: 115.81  E-value: 7.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375632526 104 HPEYGSvvaSRDLRAYLTHGPGAFCSPPWRCDLKRLMKDVNIMFRCIATSSVNVSSDSRALRRALLDFYIMGYTNQRPTR 183
Cdd:pfam02479   1 GPEYGS---DRSDRQAQLRSVGAFCPLPWTPDLARLRQDINQLFRCILRCALNPGGSANRLRRLLRDCYLMGRCRYRLKP 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1375632526 184 ACWETLLQLSSEQARPLRATLRHLN--TTEP-CDRRFLEPPtQVPPILFGQECDVS 236
Cdd:pfam02479  78 ATWERLLQLSPTQSLHLRNTLREVEarSAEPvCELPCIEAS-DSIFHRYAPECDVS 132
 
Name Accession Description Interval E-value
Herpes_IE68 pfam02479
Herpesvirus immediate early protein; This regulatory protein is expressed from an immediate ...
 104-236 7.80e-32

Herpesvirus immediate early protein; This regulatory protein is expressed from an immediate early gene in the cell cycle of herpesvirus. The protein is known by various names including IE-68, US1, ICP22 and IR4.


Pssm-ID: 280616  Cd Length: 132  Bit Score: 115.81  E-value: 7.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375632526 104 HPEYGSvvaSRDLRAYLTHGPGAFCSPPWRCDLKRLMKDVNIMFRCIATSSVNVSSDSRALRRALLDFYIMGYTNQRPTR 183
Cdd:pfam02479   1 GPEYGS---DRSDRQAQLRSVGAFCPLPWTPDLARLRQDINQLFRCILRCALNPGGSANRLRRLLRDCYLMGRCRYRLKP 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1375632526 184 ACWETLLQLSSEQARPLRATLRHLN--TTEP-CDRRFLEPPtQVPPILFGQECDVS 236
Cdd:pfam02479  78 ATWERLLQLSPTQSLHLRNTLREVEarSAEPvCELPCIEAS-DSIFHRYAPECDVS 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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