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Conserved domains on  [gi|1370511010|ref|XP_024302710|]
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caldesmon isoform X7 [Homo sapiens]

Protein Classification

Caldesmon domain-containing protein( domain architecture ID 12029883)

Caldesmon domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Caldesmon pfam02029
Caldesmon;
31-551 3.41e-159

Caldesmon;


:

Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 463.57  E-value: 3.41e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010  31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVpdEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 110
Cdd:pfam02029   1 IEDEEEAARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNSY--EEDSELKPSGQGGLDEEEAFLDRTAKREERRQKR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAeenkkedkek 190
Cdd:pfam02029  79 LQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTE---------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 191 eeeeeekpkrgsigENQGEEKGTKVQAKREKLQE-DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEF 269
Cdd:pfam02029 149 --------------VRQAEEEGEEEEDKSEEAEEvPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEE 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 270 MTHKLKHTENtfSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 349
Cdd:pfam02029 215 EVTKLKVTTK--RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELKKKREERRKL 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 350 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 429
Cdd:pfam02029 293 LEEEEQRRKQEEAERKLREEEEKRRMKEEIERRRAEAAEKRQKLPEDSSSEGKKPFKCFSPKGSSLKITERAEFLNKSLQ 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 430 KSSGVKSTHQAAIVSKIDSRLEQYTSAIE-GTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAG 508
Cdd:pfam02029 373 KSSSVKKTHPPAVVSKIDSRLEQYTSAIEsSTKEAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPGAKGTPNKETAG 452
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 1370511010 509 LKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 551
Cdd:pfam02029 453 LKVGVASRINEWLKKTPEGSKSPAPKPSDLRPGDVSGKRNLWE 495
 
Name Accession Description Interval E-value
Caldesmon pfam02029
Caldesmon;
31-551 3.41e-159

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 463.57  E-value: 3.41e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010  31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVpdEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 110
Cdd:pfam02029   1 IEDEEEAARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNSY--EEDSELKPSGQGGLDEEEAFLDRTAKREERRQKR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAeenkkedkek 190
Cdd:pfam02029  79 LQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTE---------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 191 eeeeeekpkrgsigENQGEEKGTKVQAKREKLQE-DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEF 269
Cdd:pfam02029 149 --------------VRQAEEEGEEEEDKSEEAEEvPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEE 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 270 MTHKLKHTENtfSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 349
Cdd:pfam02029 215 EVTKLKVTTK--RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELKKKREERRKL 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 350 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 429
Cdd:pfam02029 293 LEEEEQRRKQEEAERKLREEEEKRRMKEEIERRRAEAAEKRQKLPEDSSSEGKKPFKCFSPKGSSLKITERAEFLNKSLQ 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 430 KSSGVKSTHQAAIVSKIDSRLEQYTSAIE-GTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAG 508
Cdd:pfam02029 373 KSSSVKKTHPPAVVSKIDSRLEQYTSAIEsSTKEAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPGAKGTPNKETAG 452
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 1370511010 509 LKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 551
Cdd:pfam02029 453 LKVGVASRINEWLKKTPEGSKSPAPKPSDLRPGDVSGKRNLWE 495
 
Name Accession Description Interval E-value
Caldesmon pfam02029
Caldesmon;
31-551 3.41e-159

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 463.57  E-value: 3.41e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010  31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVpdEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 110
Cdd:pfam02029   1 IEDEEEAARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNSY--EEDSELKPSGQGGLDEEEAFLDRTAKREERRQKR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAeenkkedkek 190
Cdd:pfam02029  79 LQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTE---------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 191 eeeeeekpkrgsigENQGEEKGTKVQAKREKLQE-DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEF 269
Cdd:pfam02029 149 --------------VRQAEEEGEEEEDKSEEAEEvPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEE 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 270 MTHKLKHTENtfSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 349
Cdd:pfam02029 215 EVTKLKVTTK--RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELKKKREERRKL 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 350 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 429
Cdd:pfam02029 293 LEEEEQRRKQEEAERKLREEEEKRRMKEEIERRRAEAAEKRQKLPEDSSSEGKKPFKCFSPKGSSLKITERAEFLNKSLQ 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370511010 430 KSSGVKSTHQAAIVSKIDSRLEQYTSAIE-GTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAG 508
Cdd:pfam02029 373 KSSSVKKTHPPAVVSKIDSRLEQYTSAIEsSTKEAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPGAKGTPNKETAG 452
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 1370511010 509 LKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 551
Cdd:pfam02029 453 LKVGVASRINEWLKKTPEGSKSPAPKPSDLRPGDVSGKRNLWE 495
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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