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Conserved domains on  [gi|1370486055|ref|XP_024309641|]
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toll-like receptor 6 isoform X1 [Homo sapiens]

Protein Classification

toll-like receptor( domain architecture ID 17988233)

toll-like receptor (TLR) is involved in the recognition of microbial pathogens by the innate immune system, which recognize different pathogen-associated molecular patterns

CATH:  3.40.50.10140|3.80.10.10
Gene Ontology:  GO:0005515|GO:0002224|GO:0006955|GO:0004888|GO:0038187
PubMed:  18227810|16675322|34199501|16822173|11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TIR smart00255
Toll - interleukin 1 - resistance;
641-780 2.54e-38

Toll - interleukin 1 - resistance;


:

Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 139.38  E-value: 2.54e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  641 QFHAFISYSEHDsaWVKSELVPYLEK--EDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYF 718
Cdd:smart00255   1 EYDVFISYSGKE--DVRNEFLSHLLEklRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370486055  719 AHHNLFHEGSNNLILILLEPIPQNsIPNKYHKLKALMtQRTYLQWPKEKSKRglFWANIRAA 780
Cdd:smart00255  79 ALENALEEGGLRVIPIFYEVIPSD-VRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYA 136
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
249-531 4.41e-14

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.97  E-value: 4.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 249 STLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTVF 328
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 329 SEMNIMMLTISDTPFIHMLcphapSTFKFLNFTQNVFTDsIFEKCSTLVKLETLILQKNGLKDLFKVglmTKDMPSLEIL 408
Cdd:COG4886    94 DLTNLTELDLSGNEELSNL-----TNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDLPEP---LGNLTNLKSL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 409 DVSWNSLES-GRHKENCTwveSIVVLNLSSNMLTD--SVFRCLPpRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSL 485
Cdd:COG4886   165 DLSNNQLTDlPEELGNLT---NLKELDLSNNQITDlpEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1370486055 486 TDLPGCGSFSSLSVLIIDHNSVSHPSadFFQSCQKMRSIKAGDNPF 531
Cdd:COG4886   241 TDLPELGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQL 284
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
55-327 3.09e-10

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.03  E-value: 3.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  55 KVLDMSQNYIAELqVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQdLEYLDLSHNQLQKISCH--PIVSFRHLDLSFND 132
Cdd:COG4886   116 ESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTN-LKSLDLSNNQLTDLPEElgNLTNLKELDLSNNQ 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 133 FKALPicKEFGNLSQLNFLGLSAMKLQKLDlLPIAHL-HLSYILLD---------------LRNYYIKENE----TESLQ 192
Cdd:COG4886   194 ITDLP--EPLGNLTNLEELDLSGNQLTDLP-EPLANLtNLETLDLSnnqltdlpelgnltnLEELDLSNNQltdlPPLAN 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 193 ILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQF 272
Cdd:COG4886   271 LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALL 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370486055 273 LWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTV 327
Cdd:COG4886   351 TLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTL 405
LRRCT smart00082
Leucine rich repeat C-terminal domain;
529-582 1.63e-09

Leucine rich repeat C-terminal domain;


:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 53.97  E-value: 1.63e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370486055  529 NPFQCTCELREFVKNIDQvssEVLEGWPDSYKCDYPESYRGsPLKDFHMSELSC 582
Cdd:smart00082   1 NPFICDCELRWLLRWLQA---NEHLQDPVDLRCASPSSLRG-PLLELLHSEFKC 50
 
Name Accession Description Interval E-value
TIR smart00255
Toll - interleukin 1 - resistance;
641-780 2.54e-38

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 139.38  E-value: 2.54e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  641 QFHAFISYSEHDsaWVKSELVPYLEK--EDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYF 718
Cdd:smart00255   1 EYDVFISYSGKE--DVRNEFLSHLLEklRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370486055  719 AHHNLFHEGSNNLILILLEPIPQNsIPNKYHKLKALMtQRTYLQWPKEKSKRglFWANIRAA 780
Cdd:smart00255  79 ALENALEEGGLRVIPIFYEVIPSD-VRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYA 136
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 642-778 2.35e-21

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 91.66  E-value: 2.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 642 FHAFISYSEHDS-AWVKSELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAH 720
Cdd:pfam01582   1 YDVFLSFRGSDTrEWFVSHLLKELKQKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370486055 721 HNLFhEGSNNLILILLEPIPQ------NSIPNKYHKLKALMTQRTYLQWP------------KEKSKRGLFWANIR 778
Cdd:pfam01582  81 ECAL-DLGQKVIPIFYEVDPSdvrkqtGSFGKAFKKHKKVLTEEKVLKWRgalnevaniwhsKSVSDESKFWKKIA 155
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
249-531 4.41e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.97  E-value: 4.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 249 STLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTVF 328
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 329 SEMNIMMLTISDTPFIHMLcphapSTFKFLNFTQNVFTDsIFEKCSTLVKLETLILQKNGLKDLFKVglmTKDMPSLEIL 408
Cdd:COG4886    94 DLTNLTELDLSGNEELSNL-----TNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDLPEP---LGNLTNLKSL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 409 DVSWNSLES-GRHKENCTwveSIVVLNLSSNMLTD--SVFRCLPpRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSL 485
Cdd:COG4886   165 DLSNNQLTDlPEELGNLT---NLKELDLSNNQITDlpEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1370486055 486 TDLPGCGSFSSLSVLIIDHNSVSHPSadFFQSCQKMRSIKAGDNPF 531
Cdd:COG4886   241 TDLPELGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-327 3.09e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.03  E-value: 3.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  55 KVLDMSQNYIAELqVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQdLEYLDLSHNQLQKISCH--PIVSFRHLDLSFND 132
Cdd:COG4886   116 ESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTN-LKSLDLSNNQLTDLPEElgNLTNLKELDLSNNQ 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 133 FKALPicKEFGNLSQLNFLGLSAMKLQKLDlLPIAHL-HLSYILLD---------------LRNYYIKENE----TESLQ 192
Cdd:COG4886   194 ITDLP--EPLGNLTNLEELDLSGNQLTDLP-EPLANLtNLETLDLSnnqltdlpelgnltnLEELDLSNNQltdlPPLAN 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 193 ILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQF 272
Cdd:COG4886   271 LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALL 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370486055 273 LWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTV 327
Cdd:COG4886   351 TLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTL 405
LRRCT smart00082
Leucine rich repeat C-terminal domain;
529-582 1.63e-09

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 53.97  E-value: 1.63e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370486055  529 NPFQCTCELREFVKNIDQvssEVLEGWPDSYKCDYPESYRGsPLKDFHMSELSC 582
Cdd:smart00082   1 NPFICDCELRWLLRWLQA---NEHLQDPVDLRCASPSSLRG-PLLELLHSEFKC 50
LRR_8 pfam13855
Leucine rich repeat;
76-133 3.04e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 53.68  E-value: 3.04e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370486055  76 SELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKIS---CHPIVSFRHLDLSFNDF 133
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSpgaFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 353-565 1.50e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 58.32  E-value: 1.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 353 STFKFLNFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMtkDMPSLEILDVSWNSLeSGRHKENCTWVESIVV 432
Cdd:PLN00113  236 TSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIF--SLQKLISLDLSDNSL-SGEIPELVIQLQNLEI 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 433 LNLSSNMLTDSVFRCLP--PRIKVLDLHSNKIK-SVPKQVVKLEALQELNVAFNSLT-DLP-GCGSFSSLSVLIIDHNSV 507
Cdd:PLN00113  313 LHLFSNNFTGKIPVALTslPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTgEIPeGLCSSGNLFKLILFSNSL 392

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370486055 508 SHPSADFFQSCQKMRSIKAGDNPFqcTCEL-REFVK----NIDQVSSEVLEGWPDSYKCDYPE 565
Cdd:PLN00113  393 EGEIPKSLGACRSLRRVRLQDNSF--SGELpSEFTKlplvYFLDISNNNLQGRINSRKWDMPS 453
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
43-208 2.54e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 44.69  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  43 LIHVPKDLPLKTKVLDMSQNYIAELQvsdMSFLSELTVLRLSHNRIQLLDLSVfkfNQDLEYLDLSHNQLQKISCHPIVS 122
Cdd:PRK15370  232 LTSIPATLPDTIQEMELSINRITELP---ERLPSALQSLDLFHNKISCLPENL---PEELRYLSVYDNSIRTLPAHLPSG 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 123 FRHLDLSFNDFKALP-----------------ICKEFGNLSQLNFLGLSAMKLQKL-DLLP--IAHLHLSYILLdlrnYY 182
Cdd:PRK15370  306 ITHLNVQSNSLTALPetlppglktleagenalTSLPASLPPELQVLDVSKNQITVLpETLPptITTLDVSRNAL----TN 381

                         170       180
                  ....*....|....*....|....*.
gi 1370486055 183 IKENETESLQILNAKTLHLVFHPTSL 208
Cdd:PRK15370  382 LPENLPAALQIMQASRNNLVRLPESL 407
LRRCT pfam01463
Leucine rich repeat C-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 558-582 8.44e-04

Leucine rich repeat C-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the C-terminus of tandem leucine rich repeats.


Pssm-ID: 279765  Cd Length: 26  Bit Score: 37.42  E-value: 8.44e-04
                          10        20
                  ....*....|....*....|....*
gi 1370486055 558 SYKCDYPESYRGSPLKDFHMSELSC 582
Cdd:pfam01463   1 NARCASPPRLRGQPLLDLLPSDFSC 25
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 78-140 1.37e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.92  E-value: 1.37e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370486055  78 LTVLRLSHNRIQllDLSVFKFNQDLEYLDLSHNQLQKIS--CHPIVSFRHL---DLSFNdfkalPICK 140
Cdd:cd21340   122 LRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLrelDLTGN-----PVCK 182
LRR_8 pfam13855
Leucine rich repeat;
450-505 2.08e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 2.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 450 PRIKVLDLHSNKIKSVPKQV-VKLEALQELNVAFNSLTDLPGcGSFS---SLSVLIIDHN 505
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSP-GAFSglpSLRYLDLSGN 59
 
Name Accession Description Interval E-value
TIR smart00255
Toll - interleukin 1 - resistance;
641-780 2.54e-38

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 139.38  E-value: 2.54e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  641 QFHAFISYSEHDsaWVKSELVPYLEK--EDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYF 718
Cdd:smart00255   1 EYDVFISYSGKE--DVRNEFLSHLLEklRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370486055  719 AHHNLFHEGSNNLILILLEPIPQNsIPNKYHKLKALMtQRTYLQWPKEKSKRglFWANIRAA 780
Cdd:smart00255  79 ALENALEEGGLRVIPIFYEVIPSD-VRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYA 136
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 642-778 2.35e-21

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 91.66  E-value: 2.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 642 FHAFISYSEHDS-AWVKSELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAH 720
Cdd:pfam01582   1 YDVFLSFRGSDTrEWFVSHLLKELKQKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370486055 721 HNLFhEGSNNLILILLEPIPQ------NSIPNKYHKLKALMTQRTYLQWP------------KEKSKRGLFWANIR 778
Cdd:pfam01582  81 ECAL-DLGQKVIPIFYEVDPSdvrkqtGSFGKAFKKHKKVLTEEKVLKWRgalnevaniwhsKSVSDESKFWKKIA 155
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
 645-738 3.45e-18

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 80.82  E-value: 3.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 645 FISYSEHDSAWVKsELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHnlF 724
Cdd:pfam13676   2 FISYAGEDRAWAE-WLADALEAAGYRVWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALA--D 78

                          90
                  ....*....|....
gi 1370486055 725 HEGSNNLILILLEP 738
Cdd:pfam13676  79 PEGRKRLIPVRLEC 92
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
249-531 4.41e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.97  E-value: 4.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 249 STLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTVF 328
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 329 SEMNIMMLTISDTPFIHMLcphapSTFKFLNFTQNVFTDsIFEKCSTLVKLETLILQKNGLKDLFKVglmTKDMPSLEIL 408
Cdd:COG4886    94 DLTNLTELDLSGNEELSNL-----TNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDLPEP---LGNLTNLKSL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 409 DVSWNSLES-GRHKENCTwveSIVVLNLSSNMLTD--SVFRCLPpRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSL 485
Cdd:COG4886   165 DLSNNQLTDlPEELGNLT---NLKELDLSNNQITDlpEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1370486055 486 TDLPGCGSFSSLSVLIIDHNSVSHPSadFFQSCQKMRSIKAGDNPF 531
Cdd:COG4886   241 TDLPELGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
356-546 1.66e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.88  E-value: 1.66e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 356 KFLNFTQNVFTDsIFEKCSTLVKLETLILQKNGLKDLFKVglmTKDMPSLEILDVSWNSLESGRHK-ENCTwveSIVVLN 434
Cdd:COG4886   139 KELDLSNNQLTD-LPEPLGNLTNLKSLDLSNNQLTDLPEE---LGNLTNLKELDLSNNQITDLPEPlGNLT---NLEELD 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 435 LSSNMLTD---SVFRClpPRIKVLDLHSNKIKSVPkQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPS 511
Cdd:COG4886   212 LSGNQLTDlpePLANL--TNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLK 288

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1370486055 512 ADFFQSCQKMRSIKAGDNPFQCTCELREFVKNIDQ 546
Cdd:COG4886   289 LKELELLLGLNSLLLLLLLLNLLELLILLLLLTTL 323
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-327 3.09e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.03  E-value: 3.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  55 KVLDMSQNYIAELqVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQdLEYLDLSHNQLQKISCH--PIVSFRHLDLSFND 132
Cdd:COG4886   116 ESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTN-LKSLDLSNNQLTDLPEElgNLTNLKELDLSNNQ 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 133 FKALPicKEFGNLSQLNFLGLSAMKLQKLDlLPIAHL-HLSYILLD---------------LRNYYIKENE----TESLQ 192
Cdd:COG4886   194 ITDLP--EPLGNLTNLEELDLSGNQLTDLP-EPLANLtNLETLDLSnnqltdlpelgnltnLEELDLSNNQltdlPPLAN 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 193 ILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQF 272
Cdd:COG4886   271 LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALL 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370486055 273 LWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTV 327
Cdd:COG4886   351 TLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTL 405
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-283 5.06e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 62.26  E-value: 5.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  55 KVLDMSQNYIAELQVSdMSFLSELTVLRLSHNRIQLLDLSVFKFNQdLEYLDLSHNQLQKISC-HPIVSFRHLDLSFNDF 133
Cdd:COG4886   185 KELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPEPLANLTN-LETLDLSNNQLTDLPElGNLTNLEELDLSNNQL 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 134 KALPICKEFGNLSQLNFLG--LSAMKLQKLDLLPIAHLHLSYILLDLRNYYIKENETESLQILNAKTLHLVFHPTSLFAI 211
Cdd:COG4886   263 TDLPPLANLTNLKTLDLSNnqLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLAL 342

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370486055 212 QVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNI 283
Cdd:COG4886   343 SLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRRCT smart00082
Leucine rich repeat C-terminal domain;
529-582 1.63e-09

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 53.97  E-value: 1.63e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370486055  529 NPFQCTCELREFVKNIDQvssEVLEGWPDSYKCDYPESYRGsPLKDFHMSELSC 582
Cdd:smart00082   1 NPFICDCELRWLLRWLQA---NEHLQDPVDLRCASPSSLRG-PLLELLHSEFKC 50
LRR_8 pfam13855
Leucine rich repeat;
76-133 3.04e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 53.68  E-value: 3.04e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370486055  76 SELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKIS---CHPIVSFRHLDLSFNDF 133
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSpgaFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 353-565 1.50e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 58.32  E-value: 1.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 353 STFKFLNFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMtkDMPSLEILDVSWNSLeSGRHKENCTWVESIVV 432
Cdd:PLN00113  236 TSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIF--SLQKLISLDLSDNSL-SGEIPELVIQLQNLEI 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 433 LNLSSNMLTDSVFRCLP--PRIKVLDLHSNKIK-SVPKQVVKLEALQELNVAFNSLT-DLP-GCGSFSSLSVLIIDHNSV 507
Cdd:PLN00113  313 LHLFSNNFTGKIPVALTslPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTgEIPeGLCSSGNLFKLILFSNSL 392

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370486055 508 SHPSADFFQSCQKMRSIKAGDNPFqcTCEL-REFVK----NIDQVSSEVLEGWPDSYKCDYPE 565
Cdd:PLN00113  393 EGEIPKSLGACRSLRRVRLQDNSF--SGELpSEFTKlplvYFLDISNNNLQGRINSRKWDMPS 453
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 353-529 2.31e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 47.92  E-value: 2.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 353 STFKFLNFTQNVFTDSIfeKCSTLVKLETLILQKNGLKdlfkvGLMTKDM---PSLEILDVSWNSLeSGRHKENCTWVES 429
Cdd:PLN00113  118 SSLRYLNLSNNNFTGSI--PRGSIPNLETLDLSNNMLS-----GEIPNDIgsfSSLKVLDLGGNVL-VGKIPNSLTNLTS 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 430 IVVLNLSSNMLTDSVFRCLpPRIKVLDL----HSNKIKSVPKQVVKLEALQELNVAFNSLTDL--PGCGSFSSLSVLIID 503
Cdd:PLN00113  190 LEFLTLASNQLVGQIPREL-GQMKSLKWiylgYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPipSSLGNLKNLQYLFLY 268

                         170       180
                  ....*....|....*....|....*.
gi 1370486055 504 HNSVSHPSADFFQSCQKMRSIKAGDN 529
Cdd:PLN00113  269 QNKLSGPIPPSIFSLQKLISLDLSDN 294
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
352-489 6.32e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 46.61  E-value: 6.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 352 PSTFKFLNFTQNVFTDsIFEKCSTlvKLETLILQKNglkdlfKVGLMTKDMPS-LEILDVSWNSLES-GRHKENctwveS 429
Cdd:PRK15370  240 PDTIQEMELSINRITE-LPERLPS--ALQSLDLFHN------KISCLPENLPEeLRYLSVYDNSIRTlPAHLPS-----G 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 430 IVVLNLSSNMLT----------------DSVFRCLP----PRIKVLDLHSNKIKSVPKQVVKleALQELNVAFNSLTDLP 489
Cdd:PRK15370  306 ITHLNVQSNSLTalpetlppglktleagENALTSLPaslpPELQVLDVSKNQITVLPETLPP--TITTLDVSRNALTNLP 383
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
47-180 1.18e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 45.31  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  47 PKDLPLKTKVLDMSQNYIAELQVSDMSFLSELTVLRLSHNRiQLLDLSvfkfnqDLEYLDLSHNQLQKI--SCHPIVSFR 124
Cdd:COG4886    67 LLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-ELSNLT------NLESLDLSGNQLTDLpeELANLTNLK 139

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370486055 125 HLDLSFNDFKALPicKEFGNLSQLNFLGLSAMKLQKLDlLPIAHL-HLSYilLDLRN 180
Cdd:COG4886   140 ELDLSNNQLTDLP--EPLGNLTNLKSLDLSNNQLTDLP-EELGNLtNLKE--LDLSN 191
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
378-545 1.42e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 45.46  E-value: 1.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 378 KLETLILQKNGLKDLFKvglmtKDMPSLEILDVSWNSLESGRHkencTWVESIVVLNLSSNMLTDSVFRcLPPRIKVLDL 457
Cdd:PRK15370  200 QITTLILDNNELKSLPE-----NLQGNIKTLYANSNQLTSIPA----TLPDTIQEMELSINRITELPER-LPSALQSLDL 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 458 HSNKIKSVPKQVVklEALQELNVAFNSLTDLPGCGSfSSLSVLIIDHNSVSHPSADFFQScqkMRSIKAGDNPFQCTCE- 536
Cdd:PRK15370  270 FHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLP-SGITHLNVQSNSLTALPETLPPG---LKTLEAGENALTSLPAs 343


                  ....*....
gi 1370486055 537 LREFVKNID 545
Cdd:PRK15370  344 LPPELQVLD 352
LRR_8 pfam13855
Leucine rich repeat;
55-112 1.81e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.20  E-value: 1.81e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370486055  55 KVLDMSQNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQL 112
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
43-208 2.54e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 44.69  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  43 LIHVPKDLPLKTKVLDMSQNYIAELQvsdMSFLSELTVLRLSHNRIQLLDLSVfkfNQDLEYLDLSHNQLQKISCHPIVS 122
Cdd:PRK15370  232 LTSIPATLPDTIQEMELSINRITELP---ERLPSALQSLDLFHNKISCLPENL---PEELRYLSVYDNSIRTLPAHLPSG 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 123 FRHLDLSFNDFKALP-----------------ICKEFGNLSQLNFLGLSAMKLQKL-DLLP--IAHLHLSYILLdlrnYY 182
Cdd:PRK15370  306 ITHLNVQSNSLTALPetlppglktleagenalTSLPASLPPELQVLDVSKNQITVLpETLPptITTLDVSRNAL----TN 381

                         170       180
                  ....*....|....*....|....*.
gi 1370486055 183 IKENETESLQILNAKTLHLVFHPTSL 208
Cdd:PRK15370  382 LPENLPAALQIMQASRNNLVRLPESL 407
LRRCT pfam01463
Leucine rich repeat C-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 558-582 8.44e-04

Leucine rich repeat C-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the C-terminus of tandem leucine rich repeats.


Pssm-ID: 279765  Cd Length: 26  Bit Score: 37.42  E-value: 8.44e-04
                          10        20
                  ....*....|....*....|....*
gi 1370486055 558 SYKCDYPESYRGSPLKDFHMSELSC 582
Cdd:pfam01463   1 NARCASPPRLRGQPLLDLLPSDFSC 25
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 78-140 1.37e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.92  E-value: 1.37e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370486055  78 LTVLRLSHNRIQllDLSVFKFNQDLEYLDLSHNQLQKIS--CHPIVSFRHL---DLSFNdfkalPICK 140
Cdd:cd21340   122 LRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLrelDLTGN-----PVCK 182
LRR_8 pfam13855
Leucine rich repeat;
450-505 2.08e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 2.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 450 PRIKVLDLHSNKIKSVPKQV-VKLEALQELNVAFNSLTDLPGcGSFS---SLSVLIIDHN 505
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSP-GAFSglpSLRYLDLSGN 59
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 358-450 5.98e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055 358 LNFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLmtKDMPSLEILDVSWNSLeSGRHKENCTWVESIVVLNLSS 437
Cdd:PLN00113  504 LKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASF--SEMPVLSQLDLSQNQL-SGEIPKNLGNVESLVQVNISH 580

                          90
                  ....*....|...
gi 1370486055 438 NMLTDSvfrcLPP 450
Cdd:PLN00113  581 NHLHGS----LPS 589
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 53-148 9.30e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.45  E-value: 9.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486055  53 KTKVLDMSQNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQ-----KISCHPIVSfrHLD 127
Cdd:PLN00113  476 RLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgqipaSFSEMPVLS--QLD 553

                          90       100
                  ....*....|....*....|.
gi 1370486055 128 LSFNDFKAlPICKEFGNLSQL 148
Cdd:PLN00113  554 LSQNQLSG-EIPKNLGNVESL 573
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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